論文 - 古川 智範
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Effects of voluntary and forced exercise on brain health in adult rats.
Sato C, Chiba M, Furukawa T, Koeda S, Mikami M, Hatakenaka K, Nunomura T, Umamichi K, Miura H, Yamada J.
Journal of Brain Science 2024年03月
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Altered amantadine effects after repetitive treatment for l-dopa-induced involuntary movements in a rat model of Parkinson's disease.
Murakami Y, Nishijima H, Nakamura T, Furukawa T, Kinoshita I, Kon T, Suzuki C, Tomiyama M
Neuroscience letters 806 137248 - 137248 2023年05月
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Effect of Ionizing Radiation on the Intercellular Network of Murine Cerebral Cortical Neurons
Yamaguchi Masaru, Tsujiguchi Takakiyo, Furukawa Tomonori, Shimoyama Shuji, Nakamura Toshiya, Mariya Yasushi, Yamada Junko
Radiation Environment and Medicine 12 ( 1 ) 65 - 73 2023年02月
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Pathological substrate of memory impairment in multiple system atrophy.
Miki Y, Tanji K, Shinnai K, Tanaka MT, Altay F, Foti SC, Strand C, Sasaki T, Kon T, Shimoyama S, Furukawa T, Nishijima H, Yamazaki H, Asi YT, Bettencourt C, Jaunmuktane Z, Tada M, Mori F, Mizukami H, Tomiyama M, Lashuel HA, Lashley T, Kakita A, Ling H, Lees AJ, Holton JL, Warner TT, Wakabayashi K
Neuropathology and applied neurobiology 48 ( 7 ) e12844 2022年12月
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The role of neutrophil gelatinase-associated lipocalin and iron homeostasis in object recognition impairment in aged sepsis-survivor rats.
Nikaido Y, Midorikawa Y, Furukawa T, Shimoyama S, Takekawa D, Kitayama M, Ueno S, Kushikata T, Hirota K
Scientific reports 12 ( 1 ) 249 - 249 2022年01月
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Impaired Cognitive Function and Hippocampal Changes Following Chronic Diazepam Treatment in Middle-Aged Mice.
Furukawa T, Nikaido Y, Shimoyama S, Masuyama N, Notoya A, Ueno S
Frontiers in aging neuroscience 13 777404 - 777404 2021年11月
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Copy number variations in Japanese children with autism spectrum disorder.
Yui Sakamoto, Shuji Shimoyama, Tomonori Furukawa, Masaki Adachi, Michio Takahashi, Tamaki Mikami, Michito Kuribayashi, Ayako Osato, Daiki Tsushima, Manabu Saito, Shinya Ueno, Kazuhiko Nakamura
Psychiatric genetics 31 ( 3 ) 79 - 87 2021年06月
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GABAA Receptors and Maternally Derived Taurine Regulate the Temporal Specification of Progenitors of Excitatory Glutamatergic Neurons in the Mouse Developing Cortex.
Shiro Tochitani, Tomonori Furukawa, Ryo Bando, Shigeaki Kondo, Takashi Ito, Yoshitaka Matsushima, Toshio Kojima, Hideo Matsuzaki, Atsuo Fukuda
Cerebral cortex (New York, N.Y. : 1991) 2021年05月
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GABAA Receptors and Maternally Derived Taurine Regulate the Temporal Specification of Progenitors of Excitatory Glutamatergic Neurons in the Mouse Developing Cortex.
Tochitani S, Furukawa T, Bando R, Kondo S, Ito T, Matsushima Y, Kojima T, Matsuzaki H, Fukuda A
Cerebral cortex (New York, N.Y. : 1991) 31 ( 10 ) 4554 - 4575 2021年05月
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Lipopolysaccharide induces mouse translocator protein (18 kDa) expression via the AP-1 complex in the microglial cell line, BV-2.
Shuji Shimoyama, Tomonori Furukawa, Yoshiki Ogata, Yoshikazu Nikaido, Kohei Koga, Yui Sakamoto, Shinya Ueno, Kazuhiko Nakamura
PloS one 14 ( 9 ) e0222861 - e0222861 2019年09月
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Phospholipase C-related inactive protein type-1 deficiency affects anesthetic electroencephalogram activity induced by propofol and etomidate in mice.
Furukawa T, Nikaido Y, Shimoyama S, Ogata Y, Kushikata T, Hirota K, Kanematsu T, Hirata M, Ueno S
Journal of anesthesia 33 ( 4 ) 531 - 542 2019年08月
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Phospholipase C-related inactive protein type-1 deficiency affects anesthetic electroencephalogram activity induced by propofol and etomidate in mice.
Tomonori Furukawa, Yoshikazu Nikaido, Shuji Shimoyama, Yoshiki Ogata, Tetsuya Kushikata, Kazuyoshi Hirota, Takashi Kanematsu, Masato Hirata, Shinya Ueno
Journal of anesthesia 33 ( 4 ) 531 - 542 2019年07月
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遺伝子Tspoの発現制御メカニズムの解明
下山 修司, 古川 智範, 小潟 佳輝, 中村 和彦, 上野 伸哉
弘前医学 69 ( 1-4 ) 207 - 207 2019年03月
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Lipopolysaccharide induces mouse translocator protein (18 kDa) expression via the AP-1 complex in the microglial cell line, BV-2.
Shimoyama S, Furukawa T, Ogata Y, Nikaido Y, Koga K, Sakamoto Y, Ueno S, Nakamura K
PloS one 14 ( 9 ) e0222861 2019年
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〈一般演題抄録〉遺伝子<i>Tspo</i> の発現制御メカニズムの解明
下山 修司, 古川 智範, 小潟 佳輝, 中村 和彦, 上野 伸哉
弘前医学 69 ( 1 ) 207 2019年
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Anti‐hypersensitive effect of angiotensin (1‐7) on streptozotocin‐induced diabetic neuropathic pain in mice
Ogata Yoshiki, Nemoto Wataru, Yamagata Ryota, Nakagawasai Osamu, Shimoyama Shuji, Furukawa Tomonori, Ueno Shinya, Tan-No Koichi
European Journal of Pain 23 ( 4 ) 739 - 749 2018年11月
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Chronic inflammatory pain induced GABAergic synaptic plasticity in the adult mouse anterior cingulate cortex.
Koga Kohei, Shimoyama Shuji, Yamada Akihiro, Furukawa Tomonori, Nikaido Yoshikazu, Furue Hidemasa, Nakamura Kazuhiko, Ueno Shinya.
Molecular Pain 14 ( 14 ) 1 - 14 2018年06月
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MHC Class I in Dopaminergic Neurons Suppresses Relapse to Reward Seeking
Murakami Gen, Edamura Mitsuhiro, Furukawa Tomonori, Kawasaki Hideya, Kosugi Isao, Fukuda Atsuo, Iwashita Toshihide and Nakahara Daiichiro
Science Advances 2018年03月
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MHC class I in dopaminergic neurons suppresses relapse to reward seeking.
Murakami G, Edamura M, Furukawa T, Kawasaki H, Kosugi I, Fukuda A, Iwashita T, Nakahara D
Science advances 4 ( 3 ) eaap7388 2018年03月
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Propofol Anesthesia Is Reduced in Phospholipase C-Related Inactive Protein Type-1 Knockout Mice.
Nikaido Y, Furukawa T, Shimoyama S, Yamada J, Migita K, Koga K, Kushikata T, Hirota K, Kanematsu T, Hirata M, Ueno S
The Journal of pharmacology and experimental therapeutics 361 ( 3 ) 367 - 374 2017年06月
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Propofol Anesthesia Is Reduced in Phospholipase C-Related Inactive Protein Type-1 Knockout Mice.
Nikaido Y, Furukawa T, Shimoyama S, Yamada J, Migita K, Koga K, Kushikata T, Hirota K, Kanematsu T, Hirata M, Ueno S.
J Pharmacol Exp Ther 361 ( 3 ) 367 - 374 2017年04月
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Activations of muscarinic M1 receptors in the anterior cingulate cortex contribute to the antinociceptive effect via GABAergic transmission
Kohei Koga, Yu Matsuzaki, Kenji Honda, Fumihiro Eto, Tomonori Furukawa, Keisuke Migita, Keiichi Irie, Kenichi Mishima, Shinya Ueno
Molecular Pain 13 1 - 11 2017年02月
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Chronic diazepam administration increases the expression of Lcn2 in the CNS
Tomonori Furukawa, Shuji Shimoyama, Yasuo Miki, Yoshikazu Nikaido, Kohei Koga, Kazuhiko Nakamura, Koichi Wakabayashi, Shinya Ueno
Pharmacology Research & Perspectives 5 ( 1 ) e00283 2017年01月
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〈一般演題抄録〉ジアゼパム長期投与マウス脳組織のトランスクリプトーム解析
古川 智範, 下山 修司, 二階堂 義和, 古賀 浩平, 中村 和彦, 上野 伸哉
弘前医学 67 ( 2 ) 186 2017年
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〈一般演題抄録〉ジアゼパム長期投与マウスにおける脳内 Lcn2 発現および認知機能の解析
古川 智範, 二階堂 義和, 下山 修司, 三木 康生, 古賀 浩平, 中村 和彦, 若林 孝一, 上野 伸哉
弘前医学 68 ( 1 ) 88 2017年
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〈一般演題抄録〉うつ病モデルラットは内側前頭前野機能異常を起こす
二階堂 義和, 古川 智範, 下山 修司, 古賀 浩平, 上野 伸哉
弘前医学 67 ( 2 ) 185 2017年
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HSP90 Regulation of P2X7 Receptor Function Requires an Intact Cytoplasmic C-Terminus.
Keisuke Migita, Taku Ozaki, Shuji Shimoyama, Junko Yamada, Yoshikazu Nikaido, Tomonori Furukawa, Yuko Shiba, Terrance M Egan, Shinya Ueno
Molecular pharmacology 90 ( 2 ) 116 - 126 2016年08月
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HSP90 Regulation of P2X7 Receptor Function Requires an Intact Cytoplasmic C-Terminus.
Migita K, Ozaki T, Shimoyama S, Yamada J, Nikaido Y, Furukawa T, Shiba Y, Egan TM, Ueno S
Molecular pharmacology 90 ( 2 ) 116 - 26 2016年08月
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cis-3-Hexenol and trans-2-hexenal mixture prevents development of PTSD-like phenotype in rats.
Yoshikazu Nikaido, Junko Yamada, Keisuke Migita, Yuko Shiba, Tomonori Furukawa, Toshihiro Nakashima, Shinya Ueno
Behavioural brain research 297 251 - 258 2016年01月
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cis-3-Hexenol and trans-2-hexenal mixture prevents development of PTSD-like phenotype in rats.
Nikaido Y, Yamada J, Migita K, Shiba Y, Furukawa T, Nakashima T, Ueno S
Behavioural brain research 297 251 - 8 2016年01月
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GABA<sub>A</sub> 受容体応答の制御機構
上野 伸哉, 古川 智範, 二階堂 義和, 下山 修司, 柴 祐子, 山田 順子
弘前医学 66 ( 2 ) 105 - 109 2016年
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Roles of taurine-mediated tonic GABAA receptor activation in the radial migration of neurons in the fetal mouse cerebral cortex.
Furukawa T, Yamada J, Akita T, Matsushima Y, Yanagawa Y, Fukuda A
Frontiers in cellular neuroscience 8 88 2014年
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Activity-dependent endogenous taurine release facilitates excitatory neurotransmission in the neocortical marginal zone of neonatal rats.
Qian T, Chen R, Nakamura M, Furukawa T, Kumada T, Akita T, Kilb W, Luhmann HJ, Nakahara D, Fukuda A
Frontiers in cellular neuroscience 8 33 2014年
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De Novo mutations in GNAO1, encoding a Gαo subunit of heterotrimeric G proteins, cause epileptic encephalopathy.
Nakamura K, Kodera H, Akita T, Shiina M, Kato M, Hoshino H, Terashima H, Osaka H, Nakamura S, Tohyama J, Kumada T, Furukawa T, Iwata S, Shiihara T, Kubota M, Miyatake S, Koshimizu E, Nishiyama K, Nakashima M, Tsurusaki Y, Miyake N, Hayasaka K, Ogata K, Fukuda A, Matsumoto N, Saitsu H
American journal of human genetics 93 ( 3 ) 496 - 505 2013年09月
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Cl⁻ homeodynamics in gap junction-coupled astrocytic networks on activation of GABAergic synapses.
Egawa K, Yamada J, Furukawa T, Yanagawa Y, Fukuda A
The Journal of physiology 591 ( 16 ) 3901 - 17 2013年08月
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Guidepost neurons for the lateral olfactory tract: expression of metabotropic glutamate receptor 1 and innervation by glutamatergic olfactory bulb axons.
Tatsumi Hirata, Tatsuro Kumada, Takahiko Kawasaki, Tomonori Furukawa, Atsu Aiba, François Conquet, Yumiko Saga, Atsuo Fukuda
Developmental neurobiology 72 ( 12 ) 1559 - 1576 2012年12月
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Guidepost neurons for the lateral olfactory tract: expression of metabotropic glutamate receptor 1 and innervation by glutamatergic olfactory bulb axons.
Hirata T, Kumada T, Kawasaki T, Furukawa T, Aiba A, Conquet F, Saga Y, Fukuda A
Developmental neurobiology 72 ( 12 ) 1559 - 76 2012年12月
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Taurine inhibits K+-Cl- cotransporter KCC2 to regulate embryonic Cl- homeostasis via with-no-lysine (WNK) protein kinase signaling pathway.
Inoue K, Furukawa T, Kumada T, Yamada J, Wang T, Inoue R, Fukuda A
The Journal of biological chemistry 287 ( 25 ) 20839 - 50 2012年06月
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The physiological roles of vesicular GABA transporter during embryonic development: a study using knockout mice.
Saito K, Kakizaki T, Hayashi R, Nishimaru H, Furukawa T, Nakazato Y, Takamori S, Ebihara S, Uematsu M, Mishina M, Miyazaki J, Yokoyama M, Konishi S, Inoue K, Fukuda A, Fukumoto M, Nakamura K, Obata K, Yanagawa Y
Molecular brain 3 40 2010年12月
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Low-concentration tributyltin perturbs inhibitory synaptogenesis and induces neuronal death in immature but not mature neurons.
Yamada J, Inoue K, Furukawa T, Fukuda A
Toxicology letters 198 ( 2 ) 282 - 8 2010年10月
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GABA imaging in brain slices using immobilized enzyme-linked photoanalysis.
Morishima T, Uematsu M, Furukawa T, Yanagawa Y, Fukuda A, Yoshida S
Neuroscience research 67 ( 4 ) 347 - 53 2010年08月
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Dominant-negative mutations in alpha-II spectrin cause West syndrome with severe cerebral hypomyelination, spastic quadriplegia, and developmental delay.
Saitsu H, Tohyama J, Kumada T, Egawa K, Hamada K, Okada I, Mizuguchi T, Osaka H, Miyata R, Furukawa T, Haginoya K, Hoshino H, Goto T, Hachiya Y, Yamagata T, Saitoh S, Nagai T, Nishiyama K, Nishimura A, Miyake N, Komada M, Hayashi K, Hirai S, Ogata K, Kato M, Fukuda A, Matsumoto N
American journal of human genetics 86 ( 6 ) 881 - 91 2010年06月
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Molecular basis for the GABAA receptor-mediated tonic inhibition in rat somatosensory cortex.
Yamada J, Furukawa T, Ueno S, Yamamoto S, Fukuda A
Cerebral cortex (New York, N.Y. : 1991) 17 ( 8 ) 1782 - 7 2007年08月
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Insertion of alpha7 nicotinic receptors at neocortical layer V GABAergic synapses is induced by a benzodiazepine, midazolam.
Yamamoto S, Yamada J, Ueno S, Kubota H, Furukawa T, Yamamoto S, Fukuda A
Cerebral cortex (New York, N.Y. : 1991) 17 ( 3 ) 653 - 60 2007年03月
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GABA-A receptors regulate neocortical neuronal migration in vitro and in vivo.
Heck N, Kilb W, Reiprich P, Kubota H, Furukawa T, Fukuda A, Luhmann HJ
Cerebral cortex (New York, N.Y. : 1991) 17 ( 1 ) 138 - 48 2007年01月
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Differential expression of KCC2 accounts for the differential GABA responses between relay and intrinsic neurons in the early postnatal rat olfactory bulb.
Wang C, Ohno K, Furukawa T, Ueki T, Ikeda M, Fukuda A, Sato K
The European journal of neuroscience 21 ( 5 ) 1449 - 55 2005年03月
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Brain oxytocin augments stress-induced long-lasting plasma adrenocorticotropic hormone elevation in rats.
Nakashima T, Noguchi T, Furukawa T, Yamasaki M, Makino S, Miyata S, Kiyohara T
Neuroscience letters 321 ( 3 ) 161 - 4 2002年03月