Papers - NAKAJIMA Akira
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Apple Pomace Extract Improves MK-801-Induced Memory Impairment in Mice.
Watanabe A, Shimada M, Maeda H, Narumi T, Ichita J, Itoku K, Nakajima A.
Nutrients. 2024.1
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A polysaccharide from Inula japonica showing in vivo antitumor activity by interacting with TLR-4, PD-1, and VEGF.
Wang X, Li Y, Liu W, Shen Y, Lin Z, Nakajima A, Xu J, Guo Y.
Int J Biol Macromol. 2023.8
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Iridoids from Patrinia heterophylla and their anti-inflammatory activity.
Liu W, Wu P, Song Z, Nie F, Zhang L, Lee D, Nakajima A, Xu J, Guo Y.
Phytochemistry. 2023.8
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Tetrabromobisphenol A and hexabromocyclododecane, brominated flame retardants, trigger endoplasmic reticulum stress and activate necroptosis signaling in PC12 cells.
Abe N, Sasaki M, Nakajima A.
Environ Toxicol Pharmacol. 2023.3
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Structure, anti-tumor activity, and potential anti-tumor mechanism of a fungus polysaccharide from Fomes officinalis.
Zhang S, Li Y, Li Z, Liu W, Zhang H, Ohizumi Y, Nakajima A, Xu J, Guo Y.
Carbohydr Polym. 2022.11
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Anthocyanin-rich blackcurrant extract improves long-term memory impairment and emotional abnormality in senescence-accelerated mice.
Shimada M, Maeda H, Nanashima N, Yamada K, Nakajima A.
J Food Biochem. 2022.10
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A Narrative Review of the Effects of Citrus Peels and Extracts on Human Brain Health and Metabolism.
Matsuzaki K, Nakajima A, Guo Y, Ohizumi Y.
Nutrients. 2022.4
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Isolation of adenosine and cordysinin B from Anredera cordifolia that stimulates CRE-mediated transcription in PC12 cells
Ohizumi Y, Kawada M, Kamada M, Nakajima A, Kajima K, Uozumi N, Hara Y, Guo Y, Ishibashi M
Planta Medica International Open 2021.3
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An evaluation of the genotoxicity and subchronic toxicity of the peel extract of Ponkan cultivar 'Ohta ponkan' (Citrus reticulata Blanco) that is rich in nobiletin and tangeretin with anti-dementia activity
Nakajima A, Nemoto K, Ohizumi Y
Regul Toxicol Pharmacol. 114 104670 2020.7
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Potential benefits of nobiletin, a citrus flavonoid, against Alzheimer’s disease and Parkinson’s disease.
Nakajima A, Ohizumi Y
Int J Mol Sci. E3380 2019.7
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Innate immune activation of astrocytes impairs neurodevelopment via upregulation of follistatin-like 1 and interferon-induced transmembrane protein 3.
Yamada S, Itoh N, Nagai T, Nakai T, Ibi D, Nakajima A, Nabeshima T, Yamada K
J Neuroinflammation. 15 295 2018.10
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Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes.
Sobue A, Ito N, Nagai T, Shan W, Hada K, Nakajima A, Murakami Y, Mouri A, Yamamoto Y, Nabeshima T, Saito K, Yamada K
Glia. 66 1034 - 1052 2018.5
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Fluoroquinolones and propionic acid derivatives induce inflammatory responses in vitro.
Nakajima A, Sato H, Oda S, Yokoi T
Cell Biol Toxicol. 34 65 - 77 2018
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A novel cell-based assay for the evaluation of immune- and inflammatory-related gene expression as biomarkers for the risk assessment of drug-induced liver injury.
Oda S, Matsuo K, Nakajima A, Yokoi T
Toxicol Lett. 241 60 - 70 2016
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Allopurinol induces innate immune responses through mitogen-activated protein kinase signaling pathways in HL-60 cells.
Nakajima A, Oda S, Yokoi T
J Appl Toxicol. 36 1120 - 1128 2016
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Toxicological role of an acyl glucuronide metabolite in diclofenac-induced acute liver injury in mice.
Oda S, Shirai Y, Akai S, Nakajima A, Tsuneyama K, Yokoi T
J Appl Toxicol. 37 545 - 553 2016
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Nobiletin, a citrus flavonoid, improves cognitive impairment and reduces soluble Aβ levels in a triple transgenic mouse model of Alzheimer’s disease (3XTg-AD).
Nakajima A, Aoyama Y, Shin EJ, Nam Y, Kim HC, Nagai T, Yokosuka A, Mimaki Y, Yokoi T, Ohizumi Y, Yamada K
Behav Brain Res. 269 69 - 77 2015
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Induction of interferon-induced transmembrane protein 3 gene expression by lipopolysaccharide in astrocytes.
Nakajima A, Ibi D, Nagai T, Yamada S, Nabeshima T, Yamada K
Eur J Pharmacol. 2014
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Expression of the G72/G30 gene in transgenic mice induces behavioral changes.
Cheng L, Hattori E, Nakajima A, Woehrle NS, Opal MD, Zhang C, Grennan K, Dulawa SC, Tang YP, Gershon ES, Liu C
Mol Psychiatry. 19 175 - 183 2014
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Matrix metalloproteinase-3 is a possible mediator of neurodevelopmental impairment due to polyI:C-induced innate immune activation of astrocytes.
Yamada S, Nagai T, Nakai T, Ibi D, Nakajima A, Yamada K
Brain Behav Immun. 38 272 - 282 2014