服薬に対するネガティブな意識が服薬アドヒアランスに及ぼす影響 岩木健康増進プロジェクト健診調査報告

工藤 正純, 今 良仁, 横山 智士, 金澤 佐知子, 小原 信一, 細井 一広, 照井 一史, 中川 潤一, 阿保 成慶, 津山 博匡, 兵藤 塁, 相内 尚也, 世永 早紀, 畑山 昂大, 川口 聖也, 伊藤 梢, 島田 美智子, 金城 育代[成田], 井原 一成, 中路 重之, 新岡 丈典

医薬品相互作用研究   47 ( 1 )   10 - 18   2023年03月

Impact of solute carrier transporter gene polymorphisms on serum creatinine concentrations in healthy volunteers

Yokoyama Satoshi, Nakagawa Junichi, Kudo Masakiyo, Aiuchi Naoya, Seito Tatsuya, Isida Mizuri, Mikami Tatsuya, Ihara Kazushige, Nakaji Shigeyuki, Niioka Takenori

PHARMACOLOGY RESEARCH & PERSPECTIVES   11 ( 1 )   e01048   2023年02月

Impacts of pregnane X receptor and cytochrome P450 oxidoreductase gene polymorphisms on trough concentrations of apixaban in patients with non-valvular atrial fibrillation

Nakagawa Junichi, Kinjo Takahiko, Aiuchi Naoya, Ueno Kayo, Tomita Hirofumi, Niioka Takenori

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY   79 ( 1 )   127 - 135   2023年01月

Impact of trimethoprim on serum creatinine, sodium, and potassium concentrations in patients taking trimethoprim-sulfamethoxazole without changes in glomerular filtration rate

Yokoyama Satoshi, Nakagawa Junichi, Aiuchi Naoya, Seito Tatsuya, Niioka Takenori

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS   47 ( 9 )   1409 - 1417   2022年09月

Impact of polymorphisms of pharmacokinetics-related genes and the inflammatory response on the metabolism of voriconazole

Aiuchi Naoya, Nakagawa Junichi, Sakuraba Hirotake, Takahata Takenori, Kamata Kosuke, Saito Norihiro, Ueno Kayo, Ishiyama Masahiro, Yamagata Kazufumi, Kayaba Hiroyuki, Niioka Takenori

PHARMACOLOGY RESEARCH & PERSPECTIVES   10 ( 2 )   e00935   2022年04月

免疫抑制剤TDM実施において考慮すべき点

三浦 昌朋, 見野 靖晃, 本間 真人, 新岡 丈典, 竹内 裕紀

日本臨床腎移植学会雑誌   9 ( 2 )   149 - 156   2021年12月

Impact of gene polymorphisms in drug-metabolizing enzymes and transporters on trough concentrations of rivaroxaban in patients with atrial fibrillation

Nakagawa Junichi, Kinjo Takahiko, Iizuka Mei, Ueno Kayo, Tomita Hirofumi, Niioka Takenori

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY   128 ( 2 )   297 - 304   2021年02月

Evaluation for pharmacokinetic exposure of cytotoxic anticancer drugs in elderly patients receiving (R-)CHOP therapy

Nakagawa Junichi, Takahata Takenori, Hyodo Rui, Chen Yu, Hasui Kengo, Sasaki Kota, Saito Kensuke, Ueno Kayo, Hosoi Kazuhiro, Terui Kazufumi, Sato Atsushi, Niioka Takenori

SCIENTIFIC REPORTS   11 ( 1 )   785 - 785   2021年01月

Activity and bioavailability of tepotinib for leptomeningeal metastasis of NSCLC with MET exon 14 skipping mutation

Tanaka Hisashi, Taima Kageaki, Makiguchi Tomonori, Nakagawa Junichi, Niioka Takenori, Tasaka Sadatomo

CANCER COMMUNICATIONS   41 ( 1 )   83 - 87   2021年01月

注射用抗がん薬使用状況調査に基づく医療費削減のためのdrug vial optimization実施方法に関する検討

照井 一史, 兵藤 塁, 中川 潤一, 細井 一広, 小原 信一, 本間 聖明, 明石 真弓, 佐藤 和洋, 矢田 康司, 宮崎 晃臣, 田中 南美英, 神 雅昭, 中村 一成, 山本 章二, 田村 健悦, 新岡 丈典

日本病院薬剤師会雑誌 = Journal of Japanese Society of Hospital Pharmacists   56 ( 12 )   1445 - 1451   2020年12月

Cyclosporine protects from intestinal epithelial injury by modulating butyrate uptake via upregulation of membrane monocarboxylate transporter 1 levels

Ota Shinji, Sakuraba Hirotake, Hiraga Hiroto, Yoshida Shukuko, Satake Miwa, Akemoto Yui, Tanaka Nahoko, Watanabe Rina, Takato Maeda, Murai Yasuhisa, Ueno Kayo, Niioka Takenori, Hayakari Makoto, Ishiguro Yoh, Fukuda Shinsaku

BIOCHEMISTRY AND BIOPHYSICS REPORTS   24   100811 - 100811   2020年12月

注射用抗がん薬使用状況調査に基づく医療費削減のためのdrug vial optimization実施方法に関する検討

照井 一史, 兵藤 塁, 中川 潤一, 細井 一広, 小原 信一, 本間 聖明, 明石 真弓, 佐藤 和洋, 矢田 康司, 宮崎 晃臣, 田中 南美英, 神 雅昭, 中村 一成, 山本 章二, 田村 健悦, 新岡 丈典

日本病院薬剤師会雑誌   56 ( 12 )   1445 - 1451   2020年12月

Relationship Between Change Rate of Tacrolimus Clearance During Continuous Intravenous Infusion and Recipient Recovery at an Early Stage After Living Donor Liver Transplantation

Nakagawa Junichi, Ishido Keinosuke, Tono Yuka, Kimura Norihisa, Wakiya Taiichi, Okamura Yuji, Hakamada Kenichi, Niioka Takenori

EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS   45 ( 5 )   619 - 626   2020年10月

3系統以上の抗菌薬に耐性を示す緑膿菌サーベイランスにおけるAntibiotic Heterogeneity Indexの有用性に関する検討

東野 優花, 岡村 祐嗣, 津山 博匡, 井上 文緒, 齋藤 紀先, 萱場 広之, 新岡 丈典

日本病院薬剤師会雑誌 = Journal of Japanese Society of Hospital Pharmacists   56 ( 7 )   791 - 796   2020年07月

3系統以上の抗菌薬に耐性を示す緑膿菌サーベイランスにおけるAntibiotic Heterogeneity Indexの有用性に関する検討

東野 優花, 岡村 祐嗣, 津山 博匡, 井上 文緒, 齋藤 紀先, 萱場 広之, 新岡 丈典

日本病院薬剤師会雑誌   56 ( 7 )   791 - 796   2020年07月

Association of lenvatinib trough plasma concentrations with lenvatinib-induced toxicities in Japanese patients with thyroid cancer.

Mitsuji Nagahama, Tomoko Ozeki, Akifumi Suzuki, Kiminori Sugino, Takenori Niioka, Koichi Ito, Masatomo Miura

Medical oncology (Northwood, London, England)   36 ( 5 )   39 - 39   2019年03月

Phase II Clinical Trial of Lenalidomide and Dexamethasone Therapy in Japanese Elderly Patients With Newly Diagnosed Multiple Myeloma to Determine Optimal Plasma Concentration of Lenalidomide.

Kobayashi Takahiro, Miura Masatomo, Niioka Takenori, Abumiya Maiko, Ito Fumiko, Kobayashi Isuzu, Ikeda Sho, Yoshioka Tomoko, Kameoka Yoshihiro, Takahashi Naoto

Ther Drug Monit   40 ( 3 )   301 - 309   2018年06月

The potential role of clarithromycin addition to lenalidomide and dexamethasone therapy (BiRd) in multiple myeloma.

Kobayashi Takahiro, Miura Masatomo, Abumiya Maiko, Niioka Takenori, Kanno Shuichi, Takahashi Naoto

Ann Hematol   97 ( 6 )   1097 - 1099   2018年06月

Clinical implications of pharmacokinetics of sunitinib malate and N-desethyl-sunitinib plasma concentrations for treatment outcome in metastatic renal cell carcinoma patients.

Numakura Kazuyuki, Fujiyama Nobuhiro, Takahashi Makoto, Igarashi Ryoma, Tsuruta Hiroshi, Maeno Atsushi, Huang Mingguo, Saito Mitsuru, Narita Shintaro, Inoue Takamitsu, Satoh Shigeru, Tsuchiya Norihiko, Niioka Takenori, Miura Masatomo, Habuchi Tomonori

Oncotarget   9 ( 38 )   25277 - 25284   2018年05月

Influence of CYP3A5 genetic differences in tacrolimus on quantitative interstitial fibrosis and long-term graft function in kidney transplant recipients.

Komine Naoki, Satoh Shigeru, Saito Mitsuru, Numakura Kazuyuki, Inoue Takamitsu, Tsuruta Hiroshi, Narita Shintaro, Komatsuda Atsushi, Nanjo Hiroshi, Kagaya Hideaki, Niioka Takenori, Miura Masatomo, Mitobe Yoko, Habuchi Tomonori

Int Immunopharmacol   58   57 - 63   2018年05月

Prediction of Tacrolimus Exposure by CYP3A5 Genotype and Exposure of Co-Administered Everolimus in Japanese Renal Transplant Recipients.

Kagaya Hideaki, Niioka Takenori, Saito Mitsuru, Inoue Takamitsu, Numakura Kazuyuki, Yamamoto Ryohei, Akamine Yumiko, Habuchi Tomonori, Satoh Shigeru, Miura Masatomo

Int J Mol Sci   19 ( 3 )   2018年03月

Contribution of UGT1A1 genetic polymorphisms related to axitinib pharmacokinetics to safety and efficacy in patients with renal cell carcinoma.

Igarashi Ryoma, Inoue Takamitsu, Fujiyama Nobuhiro, Tsuchiya Norihiko, Numakura Kazuyuki, Kagaya Hideaki, Saito Mitsuru, Narita Shintaro, Satoh Shigeru, Niioka Takenori, Miura Masatomo, Habuchi Tomonori

Med Oncol   35 ( 4 )   51 - 51   2018年03月

Correlation of plasma concentration and adverse effects of bosutinib: standard dose or dose-escalation regimens of bosutinib treatment for patients with chronic myeloid leukemia.

Mita Akiko, Abumiya Maiko, Miura Masatomo, Niioka Takenori, Takahashi Saori, Yoshioka Tomoko, Kameoka Yoshihiro, Takahashi Naoto

Exp Hematol Oncol   7   9 - 9   2018年

Relationship Between the CYP2C19 Phenotype Using the Voriconazole-to-Voriconazole N-Oxide Plasma Concentration Ratio and Demographic and Clinical Characteristics of Japanese Patients With Different CYP2C19 Genotypes.

Niioka Takenori, Fujishima Naohito, Abumiya Maiko, Yamashita Takaya, Ubukawa Kumi, Nara Miho, Fujishima Masumi, Takahashi Naoto, Miura Masatomo

Ther Drug Monit   39 ( 5 )   514 - 521   2017年10月

Effect of hepatic drug transporter polymorphisms on the pharmacokinetics of mycophenolic acid in patients with severe renal dysfunction before renal transplantation.

Kagaya Hideaki, Niioka Takenori, Saito Mitsuru, Inoue Takamitsu, Numakura Kazuyuki, Habuchi Tomonori, Satoh Shigeru, Miura Masatomo

Xenobiotica   47 ( 10 )   916 - 922   2017年10月

Impact of the CYP3A5 genotype on the distributions of dose-adjusted trough concentrations and incidence of rejection in Japanese renal transplant recipients receiving different tacrolimus formulations.

Niioka Takenori, Kagaya Hideaki, Saito Mitsuru, Inoue Takamitsu, Numakura Kazuyuki, Yamamoto Ryohei, Habuchi Tomonori, Satoh Shigeru, Miura Masatomo

Clin Exp Nephrol   21 ( 5 )   787 - 796   2017年10月

Low plasma concentration of gefitinib in patients with EGFR exon 21 L858R point mutations shortens progression-free survival.

Okuda Yuji, Sato Kazuhiro, Sudo Kazuhisa, Hasegawa Yukiyasu, Asano Mariko, Miura Hajime, Takeda Masahide, Sano Masaaki, Watanabe Hiroyuki, Kobayashi Hiroyuki, Niioka Takenori, Miura Masatomo, Ito Hiroshi

Cancer Chemother Pharmacol   79 ( 5 )   1013 - 1020   2017年05月

Clinical effects of single nucleotide polymorphisms on drug-related genes in Japanese metastatic renal cell carcinoma patients treated with sunitinib.

Numakura Kazuyuki, Tsuchiya Norihiko, Kagaya Hideaki, Takahashi Makoto, Tsuruta Hiroshi, Inoue Takamitsu, Narita Shintaro, Huang Mingguo, Satoh Shigeru, Niioka Takenori, Miura Masatomo, Habuchi Tomonori

Anticancer Drugs   28 ( 1 )   97 - 103   2017年01月

Quantification of Interstitial Fibrosis in Renal Allografts and Clinical Correlates of Long-Term Graft Function.

Nara Mizuho, Komatsuda Atsushi, Numakura Kazuyuki, Saito Mitsuru, Inoue Takamitsu, Niioka Takenori, Miura Masatomo, Mitobe Yoko, Okuyama Shin, Takahashi Naoto, Habuchi Tomonori, Satoh Shigeru

Am J Nephrol   46 ( 3 )   187 - 194   2017年

Therapeutic drug monitoring enables safe and effective lenalidomide therapy in patients with multiple myeloma on hemodialysis.

Kobayashi Takahiro, Niioka Takenori, Miura Masatomo, Takahashi Naoto

Ann Hematol   95 ( 12 )   2087 - 2088   2016年12月

Effects of CYP3A5 polymorphism on the pharmacokinetics of a once-daily modified-release tacrolimus formulation and acute kidney injury in hematopoietic stem cell transplantation.

Yamashita Takaya, Fujishima Naohito, Miura Masatomo, Niioka Takenori, Abumiya Maiko, Shinohara Yoshinori, Ubukawa Kumi, Nara Miho, Fujishima Masumi, Kameoka Yoshihiro, Tagawa Hiroyuki, Hirokawa Makoto, Takahashi Naoto

Cancer Chemother Pharmacol   78 ( 1 )   111 - 118   2016年07月

Effects of polymorphisms in CYP2D6 and ABC transporters and side effects induced by gefitinib on the pharmacokinetics of the gefitinib metabolite, O-desmethyl gefitinib.

Kobayashi Hiroyuki, Sato Kazuhiro, Niioka Takenori, Takeda Masahide, Okuda Yuji, Asano Mariko, Ito Hiroshi, Miura Masatomo

Med Oncol   33 ( 6 )   57 - 57   2016年06月

Influence of everolimus on the pharmacokinetics of tacrolimus in Japanese renal transplant patients.

Niioka Takenori, Kagaya Hideaki, Saito Mitsuru, Inoue Takamitsu, Numakura Kazuyuki, Yamamoto Ryohei, Akamine Yumiko, Habuchi Tomonori, Satoh Shigeru, Miura Masatomo

Int J Urol   23 ( 6 )   484 - 490   2016年06月

Effect of CYP3A5 and ABCB1 polymorphisms on the interaction between tacrolimus and itraconazole in patients with connective tissue disease.

Togashi Masaru, Niioka Takenori, Komatsuda Atsushi, Nara Mizuho, Okuyama Shin, Omokawa Ayumi, Abumiya Maiko, Wakui Hideki, Takahashi Naoto, Miura Masatomo

Eur J Clin Pharmacol   71 ( 9 )   1091 - 1097   2015年09月

Relationship Among Gefitinib Exposure, Polymorphisms of Its Metabolizing Enzymes and Transporters, and Side Effects in Japanese Patients With Non-Small-Cell Lung Cancer.

Kobayashi Hiroyuki, Sato Kazuhiro, Niioka Takenori, Miura Hajime, Ito Hiroshi, Miura Masatomo

Clin Lung Cancer   16 ( 4 )   274 - 281   2015年07月

Capability of utilizing CYP3A5 polymorphisms to predict therapeutic dosage of tacrolimus at early stage post-renal transplantation.

Niioka Takenori, Kagaya Hideaki, Saito Mitsuru, Inoue Takamitsu, Numakura Kazuyuki, Habuchi Tomonori, Satoh Shigeru, Miura Masatomo

Int J Mol Sci   16 ( 1 )   1840 - 1854   2015年01月

Effects of CYP3A5 polymorphism and the tacrolimus 12 h concentration on tacrolimus-induced acute renal dysfunction in patients with lupus nephritis.

Niioka Takenori, Komatsuda Atsushi, Kato Shotaro, Togashi Masaru, Okuyama Shin, Omokawa Ayumi, Nara Mizuho, Wakui Hideki, Takahashi Naoto, Miura Masatomo

Xenobiotica   45 ( 12 )   1147 - 1153   2015年

Characterization of clinical and genetic risk factors associated with dyslipidemia after kidney transplantation.

Numakura Kazuyuki, Kagaya Hideaki, Yamamoto Ryohei, Komine Naoki, Saito Mitsuru, Hiroshi Tsuruta, Akihama Susumu, Inoue Takamitsu, Narita Shintaro, Tsuchiya Norihiko, Habuchi Tomonori, Niioka Takenori, Miura Masatomo, Satoh Shigeru

Dis Markers   2015   179434 - 179434   2015年

Pharmacokinetic and CYP3A5 pharmacogenetic differences between once- and twice-daily tacrolimus from the first dosing day to 1 year after renal transplantation.

Satoh Shigeru, Niioka Takenori, Kagaya Hideaki, Numakura Kazuyuki, Inoue Takamitsu, Saito Mitsuru, Komine Naoki, Narita Shintaro, Tsuchiya Norihiko, Habuchi Tomonori, Miura Masatomo

Pharmacogenomics   15 ( 11 )   1495 - 1506   2014年08月

A limited sampling model to estimate exposure to lenalidomide in multiple myeloma patients.

Shida Seiji, Takahashi Naoto, Miura Masatomo, Niioka Takenori, Matsumoto Morio, Hagihara Masao, Kobayashi Takahiro, Abumiya Maiko, Kameoka Yoshihiro, Fujishima Naohito, Tagawa Hiroyuki, Hirokawa Makoto, Sawada Kenichi

Ther Drug Monit   36 ( 4 )   505 - 509   2014年08月

Multicenter phase II clinical trial of nilotinib for patients with imatinib-resistant or -intolerant chronic myeloid leukemia from the East Japan CML study group evaluation of molecular response and the efficacy and safety of nilotinib.

Takahashi Naoto, Miura Masatomo, Kuroki Jun, Mitani Kinuko, Kitabayashi Atsushi, Sasaki Osamu, Kimura Hideo, Imai Kiyotoshi, Tsukamoto Norifumi, Noji Hideyoshi, Kondo Takeshi, Motegi Mutsuhito, Kato Yuichi, Mita Masayuki, Saito Hajime, Yoshida Chikashi, Torimoto Yoshihiro, Kimura Tomofumi, Wano Yuji, Nomura Jun, Yamamoto Satoshi, Mayama Ko, Honma Riko, Sugawara Tomohiro, Sato Shinji, Shinagawa Atsushi, Abumiya Maiko, Niioka Takenori, Harigae Hideo, Sawada Kenichi

Biomark Res   2 ( 1 )   6 - 6   2014年03月

A limited sampling strategy for estimation of the area under the plasma concentration-time curve of gefitinib.

Miura Masatomo, Sato Kazuhiro, Miura Hajime, Niioka Takenori, Kobayashi Hiroyuki, Narita Chihiro, Ito Hiroshi

Ther Drug Monit   36 ( 1 )   24 - 29   2014年02月

Absence of effect of SLC22A2 genotype on cisplatin-induced nephrotoxicity in oesophageal cancer patients receiving cisplatin and 5-fluorouracil: report of results discordant with those of earlier studies.

Hinai Y, Motoyama S, Niioka T, Miura M

J Clin Pharm Ther   38 ( 6 )   498 - 503   2013年12月

Pharmaceutical and genetic determinants for interindividual differences of tacrolimus bioavailability in renal transplant recipients.

Niioka Takenori, Kagaya Hideaki, Miura Masatomo, Numakura Kazuyuki, Saito Mitsuru, Inoue Takamitsu, Habuchi Tomonori, Satoh Shigeru

Eur J Clin Pharmacol   69 ( 9 )   1659 - 1665   2013年09月

A multicenter clinical study evaluating the confirmed complete molecular response rate in imatinib-treated patients with chronic phase chronic myeloid leukemia by using the international scale of real-time quantitative polymerase chain reaction.

Shinohara Yoshinori, Takahashi Naoto, Nishiwaki Kaichi, Hino Masayuki, Kashimura Makoto, Wakita Hisashi, Hatano Yoshiaki, Hirasawa Akira, Nakagawa Yasuaki, Itoh Kuniaki, Masuoka Hidekazu, Aotsuka Nobuyuki, Matsuura Yasuhiro, Takahara Sinobu, Sano Koji, Kuroki Jun, Hata Tomoko, Nakamae Hirohisa, Mugitani Atsuko, Nakane Takahiko, Miyazaki Yasushi, Niioka Takenori, Miura Masatomo, Sawada Kenichi

Haematologica   98 ( 9 )   1407 - 1413   2013年09月

Effect of itraconazole on the concentrations of tacrolimus and cyclosporine in the blood of patients receiving allogeneic hematopoietic stem cell transplants.

Nara Miho, Takahashi Naoto, Miura Masatomo, Niioka Takenori, Kagaya Hideaki, Fujishima Naohito, Saitoh Hirobumi, Kameoka Yoshihiro, Tagawa Hiroyuki, Hirokawa Makoto, Sawada Kenichi

Eur J Clin Pharmacol   69 ( 6 )   1321 - 1329   2013年06月

A limited sampling strategy to estimate the area under the concentration-time curve of tacrolimus modified-release once-daily preparation in renal transplant recipients.

Niioka Takenori, Miura Masatomo, Kagaya Hideaki, Saito Mitsuru, Numakura Kazuyuki, Habuchi Tomonori, Satoh Shigeru

Ther Drug Monit   35 ( 2 )   228 - 232   2013年04月

小児バンコマイシン投与設計支援時に用いられる血中濃度予測系の正確度精度向上に関する検討

板垣 史郎, 早狩 誠, 工藤 正純, 新岡 丈典, 内山 道子, 金澤 佐知子, 細井 一広, 照井 一史, 小島 佳也, 保嶋 実

弘前医学   64 ( 1 )   58 - 64   2013年

Comparison of pharmacokinetics and pharmacogenetics of once- and twice-daily tacrolimus in the early stage after renal transplantation.

Niioka Takenori, Satoh Shigeru, Kagaya Hideaki, Numakura Kazuyuki, Inoue Takamitsu, Saito Mitsuru, Narita Shintaro, Tsuchiya Norihiko, Habuchi Tomonori, Miura Masatomo

Transplantation   94 ( 10 )   1013 - 1019   2012年11月

H2-receptor antagonist influences dasatinib pharmacokinetics in a patient with Philadelphia-positive acute lymphoblastic leukemia.

Matsuoka Akihito, Takahashi Naoto, Miura Masatomo, Niioka Takenori, Kawakami Kimihiro, Matsunaga Takuya, Sawada Kenichi

Cancer Chemother Pharmacol   70 ( 2 )   351 - 352   2012年08月

Pharmacokinetics of dasatinib for Philadelphia-positive acute lymphocytic leukemia with acquired T315I mutation.

Takahashi Naoto, Miura Masatomo, Scott Stuart A, Niioka Takenori, Sawada Kenichi

J Hematol Oncol   5   23 - 23   2012年05月

Different effects of the selective serotonin reuptake inhibitors fluvoxamine, paroxetine, and sertraline on the pharmacokinetics of fexofenadine in healthy volunteers.

Saruwatari Junji, Yasui-Furukori Norio, Niioka Takenori, Akamine Yumiko, Takashima Ayaka, Kaneko Sunao, Uno Tsukasa

J Clin Psychopharmacol   32 ( 2 )   195 - 199   2012年04月

Influence of H2-receptor antagonists and proton pump inhibitors on dasatinib pharmacokinetics in Japanese leukemia patients.

Takahashi Naoto, Miura Masatomo, Niioka Takenori, Sawada Kenichi

Cancer Chemother Pharmacol   69 ( 4 )   999 - 1004   2012年04月

Influence of NAT2 polymorphisms on sulfamethoxazole pharmacokinetics in renal transplant recipients.

Kagaya Hideaki, Miura Masatomo, Niioka Takenori, Saito Mitsuru, Numakura Kazuyuki, Habuchi Tomonori, Satoh Shigeru

Antimicrob Agents Chemother   56 ( 2 )   825 - 829   2012年02月

Monitoring of mycophenolic acid predose concentrations in the maintenance phase more than one year after renal transplantation.

Miura Masatomo, Niioka Takenori, Kato Shoutaro, Kagaya Hideaki, Saito Mitsuru, Habuchi Tomonori, Satoh Shigeru

Ther Drug Monit   33 ( 3 )   295 - 302   2011年06月

Pharmacogenetic determinants for interindividual difference of tacrolimus pharmacokinetics 1 year after renal transplantation.

Miura M, Niioka T, Kagaya H, Saito M, Hayakari M, Habuchi T, Satoh S

J Clin Pharm Ther   36 ( 2 )   208 - 216   2011年04月

Clinical usefulness of limited sampling strategies for estimating AUC of proton pump inhibitors.

Niioka Takenori

Yakugaku Zasshi   131 ( 3 )   407 - 413   2011年03月

Influence of CYP2C19 and ABCB1 polymorphisms on plasma concentrations of lansoprazole enantiomers after enteral administration.

Miura Masatomo, Motoyama Satoru, Hinai Yudai, Niioka Takenori, Endo Masahiro, Hayakari Makoto, Ogawa Jun-ichi

Xenobiotica   40 ( 9 )   630 - 636   2010年09月

Correlation between R/S enantiomer ratio of lansoprazole and CYP2C19 activity after single oral and enteral administration.

Miura Masatomo, Motoyama Satoru, Hinai Yudai, Niioka Takenori, Hayakari Makoto, Ogawa Jun-ichi, Suzuki Toshio

Chirality   22 ( 7 )   635 - 640   2010年07月

モンテカルロシミュレーションを用いた肺炎球菌感染が疑われる高齢者におけるレボフロキサシン適正用量の検討

岡村 祐嗣, 新岡 丈典, 木村 正彦, 保嶋 実, 早狩 誠

医療薬学   36 ( 8 )   592 - 598   2010年

CYP2C19 genotype-based (R)-warfarin disposition assessment: some views on data analysis.

Niioka Takenori, Uno Tsukasa

J Clin Pharm Ther   34 ( 5 )   611 - 612   2009年10月

Early phase limited sampling strategy characterizing tacrolimus and mycophenolic acid pharmacokinetics adapted to the maintenance phase of renal transplant patients.

Miura Masatomo, Satoh Shigeru, Niioka Takenori, Kagaya Hideaki, Saito Mitsuru, Hayakari Makoto, Habuchi Tomonori, Suzuki Toshio

Ther Drug Monit   31 ( 4 )   467 - 474   2009年08月

Comparative in vivo bioequivalence and in vitro dissolution of two valproic acid sustained-release formulations.

Fujii Akira, Yasui-Furukori Norio, Nakagami Taku, Niioka Takenori, Saito Manabu, Sato Yasushi, Kaneko Sunao

Drug Des Devel Ther   2   139 - 144   2009年02月

Estimation of the area under the concentration-time curve of racemic lansoprazole by using limited plasma concentration of lansoprazole enantiomers.

Niioka Takenori, Miura Masatomo, Uno Tsukasa, Yasui-Furukori Norio, Hayakari Makoto, Tateishi Tomonori, Suzuki Toshio

Eur J Clin Pharmacol   64 ( 5 )   503 - 509   2008年05月

Limited sampling strategy for simultaneous estimation of the area under the concentration-time curve of tacrolimus and mycophenolic acid in adult renal transplant recipients.

Miura Masatomo, Satoh Shigeru, Niioka Takenori, Kagaya Hideaki, Saito Mitsuru, Hayakari Makoto, Habuchi Tomonori, Suzuki Toshio

Ther Drug Monit   30 ( 1 )   52 - 59   2008年02月

Estimation of CYP2C19 activity by the omeprazole hydroxylation index at a single point in time after intravenous and oral administration.

Niioka Takenori, Uno Tsukasa, Sugimoto Katsuyoshi, Sugawara Kazunobu, Hayakari Makoto, Tateishi Tomonori

Eur J Clin Pharmacol   63 ( 11 )   1031 - 1038   2007年11月

Simultaneous determination of warfarin enantiomers and its metabolite in human plasma by column-switching high-performance liquid chromatography with chiral separation.

Uno Tsukasa, Niioka Takenori, Hayakari Makoto, Sugawara Kazunobu, Tateishi Tomonori

Ther Drug Monit   29 ( 3 )   333 - 339   2007年06月

Different serum concentrations of steady-state valproic acid in two sustained-release formulations.

Yasui-Furukori Norio, Saito Manabu, Nakagami Taku, Niioka Takenori, Sato Yasushi, Fujii Akira, Kaneko Sunao

Psychiatry Clin Neurosci   61 ( 3 )   308 - 312   2007年06月

Pharmacokinetics of low-dose nedaplatin and validation of AUC prediction in patients with non-small-cell lung carcinoma.

Niioka Takenori, Uno Tsukasa, Yasui-Furukori Norio, Takahata Takenori, Shimizu Mikiko, Sugawara Kazunobu, Tateishi Tomonori

Cancer Chemother Pharmacol   59 ( 5 )   575 - 580   2007年04月

Effect of itraconazole on pharmacokinetics of paroxetine: the role of gut transporters.

Yasui-Furukori Norio, Saito Manabu, Niioka Takenori, Inoue Yoshimasa, Sato Yasushi, Kaneko Sunao

Ther Drug Monit   29 ( 1 )   45 - 48   2007年02月

Absolute bioavailability and metabolism of omeprazole in relation to CYP2C19 genotypes following single intravenous and oral administrations.

Uno Tsukasa, Niioka Takenori, Hayakari Makoto, Yasui-Furukori Norio, Sugawara Kazunobu, Tateishi Tomonori

Eur J Clin Pharmacol   63 ( 2 )   143 - 149   2007年02月

Terbinafine increases the plasma concentration of paroxetine after a single oral administration of paroxetine in healthy subjects.

Yasui-Furukori Norio, Saito Manabu, Inoue Yoshimasa, Niioka Takenori, Sato Yasushi, Tsuchimine Shoko, Kaneko Sunao

Eur J Clin Pharmacol   63 ( 1 )   51 - 56   2007年01月

Identification of the time-point which gives a plasma rabeprazole concentration that adequately reflects the area under the concentration-time curve.

Niioka Takenori, Uno Tsukasa, Yasui-Furukori Norio, Shimizu Mikiko, Sugawara Kazunobu, Tateishi Tomonori

Eur J Clin Pharmacol   62 ( 10 )   855 - 861   2006年10月

Identification of a single time-point for plasma lansoprazole measurement that adequately reflects area under the concentration-time curve.

Niioka Takenori, Yasui-Furukori Norio, Uno Tsukasa, Sugawara Kazunobu, Kaneko Sunao, Tateishi Tomonori

Ther Drug Monit   28 ( 3 )   321 - 325   2006年06月

Sensitive determination of omeprazole and its two main metabolites in human plasma by column-switching high-performance liquid chromatography: application to pharmacokinetic study in relation to CYP2C19 genotypes.

Shimizu Mikiko, Uno Tsukasa, Niioka Takenori, Yaui-Furukori Norio, Takahata Takenori, Sugawara Kazunobu, Tateishi Tomonori

J Chromatogr B Analyt Technol Biomed Life Sci   832 ( 2 )   241 - 248   2006年03月

Hepatic clearance improves after angioplasty of the hepatic vein.

Narumi S, Hakamada K, Toyoki Y, Totsuka E, Niioka T, Umehara Y, Ono H, Nishimura A, Yoshihara S, Sasaki M

Transplant Proc   36 ( 10 )   3091 - 3092   2004年12月

消化器外科領域における至適抗菌剤使用に関する検討

鳴海 俊治, 新岡 丈典, 袴田 健一, 吉原 秀一, 小田桐 弘毅, 川崎 仁司, 十束 英志, 豊木 嘉一, 森田 隆幸, 佐々木 睦男

日本消化器外科学会雑誌   36 ( 7 )   2003年07月

当院消化器外科における入院患者の腎機能と腎排泄型薬剤の使用動向との関係

新岡 丈典, 竹内 博行, 鳴海 俊治, 川崎 仁司, 袴田 健一, 小田桐 弘毅, 森田 隆幸, 佐々木 睦男, 佐藤 淳也, 菅原 和信

医療薬学 = Japanese journal of pharmaceutical health care and sciences   27 ( 4 )   399 - 405   2001年08月

臨床への薬物動態学

猪爪信夫，岩川精吾，上野和行，加藤美紀，黒沢菜穗子，齊藤嘉津彦，菅原和信，戸田貴大，豊口禎子，灘井雅行，新岡丈典，長谷川高明，平田純生，福島昭二，和田育男，渡邊真知子，渡辺善照．（ 担当： 共著）

廣川書店  2009年4月 

2022年度，臨床薬理・和漢薬学，専門教育科目（学部）

2022年度，臨床薬理学演習，博士一貫課程・博士後期課程

2022年度，臨床薬理学講義，博士一貫課程・博士後期課程

2021年度，臨床薬理・和漢薬学，専門教育科目（学部）

2021年度，臨床薬理学演習，博士一貫課程・博士後期課程

2021年度，臨床薬理学講義，博士一貫課程・博士後期課程

2020年度，医療安全学，専門教育科目（学部）

2020年度，臨床薬理・和漢薬学，専門教育科目（学部）

2020年度，臨床薬理学演習，博士一貫課程・博士後期課程

2020年度，臨床薬理学講義，博士一貫課程・博士後期課程

2019年度，医療安全学，専門教育科目（学部）

2019年度，臨床薬理・和漢薬学，専門教育科目（学部）

2019年度，臨床薬理学演習，博士一貫課程・博士後期課程

2019年度，臨床薬理学講義，博士一貫課程・博士後期課程