日本移植学会

Polygonum tinctorium leaf extract ameliorates high-fat diet-induced intestinal epithelial damage in mice.

Kawaguchi S, Sakuraba H, Kikuchi H, Matsuki K, Hayashi Y, Ding J, Tanaka Y, Seya K, Matsumiya T, Hiraga H, Fukuda S, Sasaki K, Imaizumi T

Experimental and therapeutic medicine   25 ( 3 )   112   2023.3

The double-stranded RNA-dependent protein kinase PKR negatively regulates the protein expression of IFN-β induced by RIG-I signaling.

Matsumiya T, Shiba Y, Ding J, Kawaguchi S, Seya K, Imaizumi T

FASEB journal : official publication of the Federation of American Societies for Experimental Biology   37 ( 2 )   e22780   2023.2

Corrigendum to "Elucidation of the inhibitory effect of (+)-hopeaphenol on polyinosinicepolycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells" [Journal of Pharmacological Sciences 149 (2022) 147-157].

Xu L, Yu Z, Uekusa Y, Kawaguchi S, Kikuchi H, Daitoku K, Minakawa M, Motomura S, Furukawa KI, Oshima Y, Seya K, Imaizumi T

Journal of pharmacological sciences   151 ( 1 )   63 - 64   2023.1

ER export signals mediate plasma membrane localization of transmembrane protein TMEM72.

Ding J, Matsumiya T, Miki Y, Hayakari R, Shiba Y, Kawaguchi S, Seya K, Imaizumi T

The FEBS journal   2022.12

Glomerular endothelial expression of type I IFN-stimulated gene, DExD/H-Box helicase 60 via toll-like receptor 3 signaling: possible involvement in the pathogenesis of lupus nephritis.

Karasawa T, Sato R, Imaizumi T, Hashimoto S, Fujita M, Aizawa T, Tsugawa K, Kawaguchi S, Seya K, Terui K, Tanaka H

Renal failure   44 ( 1 )   137 - 145   2022.12

Toll-like receptor 3 signaling induces interferon-induced transmembrane protein 1 in BEAS-2B cells.

Dobashi M, Shiratori T, Imaizumi T, Hashimoto S, Kawaguchi S, Seya K, Tasaka S

Experimental biology and medicine (Maywood, N.J.)   247 ( 21 )   1917 - 1922   2022.11

Tryptanthrin attenuates TLR3-mediated STAT1 activation in THP-1 cells.

Numao N, Kawaguchi S, Ding J, Karasawa T, Seya K, Matsumiya T, Kikuchi H, Sakuraba H, Fukuda S, Imaizumi T

Immunologic research   70 ( 5 )   688 - 697   2022.10

Elucidation of the inhibitory effect of (+)-hopeaphenol on polyinosinic-polycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells.

Xu L, Yu Z, Uekusa Y, Kawaguchi S, Kikuchi H, Daitoku K, Minakawa M, Motomura S, Furukawa KI, Oshima Y, Seya K, Imaizumi T

Journal of pharmacological sciences   149 ( 3 )   147 - 157   2022.7

Porphyromonas gingivalis lipopolysaccharide induces interleukin-6 and c-c motif chemokine ligand 2 expression in cultured hCMEC/D3 human brain microvascular endothelial cells.

Sato N, Matsumoto T, Kawaguchi S, Seya K, Matsumiya T, Ding J, Aizawa T, Imaizumi T

Gerodontology   39 ( 2 )   139 - 147   2022.6

Hepatic Macrophages Express Melanoma Differentiation-Associated Gene 5 in Nonalcoholic Steatohepatitis.

Kawaguchi S, Sakuraba H, Horiuchi M, Ding J, Matsumiya T, Seya K, Iino C, Endo T, Kikuchi H, Yoshida S, Hiraga H, Fukuda S, Imaizumi T

Inflammation   45 ( 1 )   343 - 355   2022.2

Effect of sera from lupus patients on the glomerular endothelial fibrinolysis system.

Sato R, Aizawa T, Imaizumi T, Tsugawa K, Kawaguchi S, Seya K, Terui K, Tanaka H

Pediatrics international : official journal of the Japan Pediatric Society   64 ( 1 )   e15099   2022.1

Ketamine Does Not Change Natural Killer Cell Cytotoxicity in Patients Undergoing Cancer Surgery: Basic Experiment and Clinical Trial.

Kubota M, Niwa H, Seya K, Kawaguchi J, Kushikata T, Hirota K

Journal of oncology   2022   8946269   2022

Expression of Zinc-Finger Antiviral Protein in hCMEC/D3 Human Cerebral Microvascular Endothelial Cells: Effect of a Toll-Like Receptor 3 Agonist.

Okudera M, Odawara M, Arakawa M, Kawaguchi S, Seya K, Matsumiya T, Sato R, Ding J, Morita E, Imaizumi T

Neuroimmunomodulation   29 ( 4 )   1 - 10   2021.12

Inhibitory effect of anti-malarial agents on the expression of proinflammatory chemokines via Toll-like receptor 3 signaling in human glomerular endothelial cells.

Sato R, Imaizumi T, Aizawa T, Watanabe S, Tsugawa K, Kawaguchi S, Seya K, Matsumiya T, Tanaka H

Renal failure   43 ( 1 )   643 - 650   2021.12

Expression of IFN-induced transmembrane protein 1 in glomerular endothelial cells.

Hashimoto S, Imaizumi T, Watanabe S, Aizawa T, Tsugawa K, Kawaguchi S, Seya K, Matsumiya T, Tanaka H

Pediatrics international : official journal of the Japan Pediatric Society   63 ( 9 )   1075 - 1081   2021.9

Daily Brazilian green propolis intake elevates blood artepillin C levels in humans.

Ding J, Matsumiya T, Hayakari R, Shiba Y, Kawaguchi S, Seya K, Ueno K, Imaizumi T

Journal of the science of food and agriculture   101 ( 11 )   4855 - 4861   2021.8

Interleukin-6 via Toll-Like Receptor 3 Signaling Attenuates the Expression of Proinflammatory Chemokines in Human Podocytes.

Umetsu H, Watanabe S, Imaizumi T, Aizawa T, Tsugawa K, Kawaguchi S, Seya K, Matsumiya T, Tanaka H

Kidney & blood pressure research   46 ( 2 )   207 - 218   2021

Preliminary study on local medical treatment of aortic valve calcification: Drug delivery to aortic valve in rat

Yu Zaiqiang, Liu Xu, Daitoku Kazuyuki, Furukawa Ken-Ichi, Fukuda Ikuo, Motomura Shigeru, Seya Kazuhiko

Hirosaki Medical Journal   71 ( 2-4 )   101 - 107   2021

Expression of IFN-induced Transmembrane Protein 1 in Glomerular Endothelial Cells.

Shun Hashimoto, Tadaatsu Imaizumi, Shojiro Watanabe, Tomomi Aizawa, Koji Tsugawa, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Hiroshi Tanaka

Pediatrics international : official journal of the Japan Pediatric Society   2020.12

Endothelial expression of fractalkine (CX3CL1) is induced by Toll-like receptor 3 signaling in cultured human glomerular endothelial cells.

Hirono K, Imaizumi T, Aizawa T, Watanabe S, Tsugawa K, Shiratori T, Kawaguchi S, Seya K, Matsumiya T, Ito E, Tanaka H

Modern rheumatology   30 ( 6 )   1074 - 1081   2020.11

Correction to: Warfarin calcifies human aortic valve interstitial cells at high-phosphate conditions via pregnane X receptor.

Yu Z, Seya K, Chiyoya M, Daitoku K, Motomura S, Imaizumi T, Fukuda I, Furukawa KI

Journal of bone and mineral metabolism   38 ( 3 )   418 - 419   2020.5

ISG56 is involved in CXCL10 expression induced by TLR3 signaling in BEAS-2B bronchial epithelial cells.

Shiratori T, Imaizumi T, Hirono K, Kawaguchi S, Matsumiya T, Seya K, Tasaka S

Experimental lung research   46 ( 6 )   195 - 202   2020.5

Menaquinone-4 Accelerates Calcification of Human Aortic Valve Interstitial Cells in High-Phosphate Medium through PXR.

Yang W, Yu Z, Chiyoya M, Liu X, Daitoku K, Motomura S, Imaizumi T, Fukuda I, Furukawa KI, Tsuji M, Seya K

The Journal of pharmacology and experimental therapeutics   372 ( 3 )   277 - 284   2020.3

Interferon-induced transmembrane protein 1 and Myxovirus resistance protein 1 are induced by polyinosinic-polycytidylic acid in cultured hCMEC/D3 human cerebral microvascular endothelial cells.

Imaizumi T, Satake U, Miyashita R, Kawaguchi S, Matsumiya T, Seya K, Ding J, Tanaka H

Journal of neuroimmunology   337   577047   2019.12

Melanoma Differentiation-Associated Gene 5 Positively Modulates TNF-α-Induced CXCL10 Expression in Cultured HuH-7 and HLE Cells.

Kawaguchi, Sakuraba H, Haga T, Matsumiya T, Seya K, Endo T, Sawada N, Iino C, Kikuchi H, Hiraga H, Fukuda S, Imaizumi

Inflammation   2019.12

Endothelial expression of fractalkine (CX3CL1) is induced by Toll-like receptor 3 signaling in cultured human glomerular endothelial cells.

Hirono K, Imaizumi T, Aizawa T, Watanabe S, Tsugawa K, Shiratori T, Kawaguchi S, Seya K, Matsumiya T, Ito E, Tanaka H.

Modern Rheumatology   2019.11

Warfarin calcifies human aortic valve interstitial cells at high-phosphate conditions via pregnane X receptor.

Yu Z, Seya K, Chiyoya M, Daitoku K, Motomura S, Imaizumi T, Fukuda I, Furukawa KI

Journal of bone and mineral metabolism   37 ( 6 )   944 - 956   2019.11

Cytosolic Sensors of Viral RNA Are Involved in the Production of Interleukin-6 via Toll-Like Receptor 3 Signaling in Human Glomerular Endothelial Cells.

Qiang Liu, Tadaatsu Imaizumi, Tomomi Aizawa, Koji Hirono, Shogo Kawaguchi, Shojiro Watanabe, Koji Tsugawa, Tomoh Matsumiya, Kazuhiko Seya, Hidemi Yoshida, Hiroshi Tanaka

Kidney & blood pressure research   44 ( 1 )   62 - 71   2019.1

Effect of low-concentration amyloid-β 1–42 (Aβ42) on human neuroblastoma SH-SY5Y cell viability: neuroprotective potential of combination use with carnosic acid, rebamipide, edaravone, and resveratrol

Yoshida Hidemi, Hashimoto Yuko, Fukushima Takashi, Tanji Kunikazu, Matsumiya Tomoh, Seya Kazuhiko, Kawaguchi Shogo, Imaizumi Tadaatsu

Hirosaki Medical Journal   70 ( 1 )   24 - 38   2019

Interferon-stimulated gene 60 (ISG60) constitutes a negative feedback loop in the downstream of TLR3 signaling in hCMEC/D3 cells.

Tadaatsu Imaizumi, Naoko Sassa, Shogo Kawaguchi, Tomoh Matsumiya, Hidemi Yoshida, Kazuhiko Seya, Toshihiro Shiratori, Koji Hirono, Hiroshi Tanaka

Journal of neuroimmunology   324   16 - 21   2018.11

Interferon-stimulated gene 60 (ISG60) constitutes a negative feedback loop in the downstream of TLR3 signaling in hCMEC/D3 cells.

Imaizumi T, Sassa N, Kawaguchi S, Matsumiya T, Yoshida H, Seya K, Shiratori T, Hirono K, Tanaka H

Journal of neuroimmunology   324   16 - 21   2018.11

<b>Gnetin C suppresses double-stranded RNA-induced C-C motif chemokine ligand 2 (CCL2) and CCL5 production by inhibiting Toll-like receptor 3 signaling </b><b>pathway </b>

YOSHIDA Hidemi, IMAIZUMI Tadaatsu, MATSUMIYA Tomoh, SEYA Kazuhiko, KAWAGUCHI Shogo, TANAKA Hiroshi

Biomedical Research   39 ( 5 )   231 - 240   2018.10

<b>Gnetin C, a resveratrol dimer, reduces amyloid-β 1–42 (Aβ42) production and ameliorates Aβ42-lowered cell viability in cultured SH-SY5Y human neuroblastoma </b><b>cells </b>

SEINO Syota, KIMOTO Takeru, YOSHIDA Hidemi, TANJI Kunikazu, MATSUMIYA Tomoh, HAYAKARI Ryo, SEYA Kazuhiko, KAWAGUCHI Shogo, TSURUGA Kazushi, TANAKA Hiroshi, IMAIZUMI Tadaatsu

Biomedical Research   39 ( 3 )   105 - 115   2018.6

Gnetin C suppresses double-stranded RNA-induced C-C motif chemokine ligand 2 (CCL2) and CCL5 production by inhibiting Toll-like receptor 3 signaling pathway.

Hidemi Yoshida, Tadaatsu Imaizumi, Tomoh Matsumiya, Kazuhiko Seya, Shogo Kawaguchi, Hiroshi Tanaka

Biomedical research (Tokyo, Japan)   39 ( 5 )   231 - 240   2018.5

Matrix Gla protein negatively regulates calcification of human aortic valve interstitial cells isolated from calcified aortic valves.

Mari Chiyoya, Kazuhiko Seya, Zaiqiang Yu, Kazuyuki Daitoku, Shigeru Motomura, Tadaatsu Imaizumi, Ikuo Fukuda, Ken-Ichi Furukawa

Journal of pharmacological sciences   136 ( 4 )   257 - 265   2018.4

Matrix Gla protein negatively regulates calcification of human aortic valve interstitial cells isolated from calcified aortic valves.

Chiyoya M, Seya K, Yu Z, Daitoku K, Motomura S, Imaizumi T, Fukuda I, Furukawa KI

Journal of pharmacological sciences   136 ( 4 )   257 - 265   2018.4

Gnetin C, a resveratrol dimer, reduces amyloid-β 1-42 (Aβ42) production and ameliorates Aβ42-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells.

Syota Seino, Takeru Kimoto, Hidemi Yoshida, Kunikazu Tanji, Tomoh Matsumiya, Ryo Hayakari, Kazuhiko Seya, Shogo Kawaguchi, Kazushi Tsuruga, Hiroshi Tanaka, Tadaatsu Imaizumi

Biomedical research (Tokyo, Japan)   39 ( 3 )   105 - 115   2018.3

ネパールにおける文字情報サービスに関する支援

瀬谷和彦

ノーマライゼーション: 障害者の福祉   2018.2

〈一般演題抄録〉ワルファリンによる大動脈弁異所性石灰化促進作用

于 在強, 千代谷 真理, 大徳 和之, 瀬谷 和彦, 古川 賢一, 福田 幾夫

弘前医学   68 ( 2-4 )   188   2018

TNF-α induces calcification of cultured human aortic valve interstitial cells obtained from patients with calcific aortic stenosis: involvement of BMP2

Seya Kazuhiko, Yu Zaiqiang, Chiyoya Mari, Daitoku Kazuyuki, Motomura Shigeru, Imaizumi Tadaatsu, Fukuda Ikuo, Furukawa Ken-Ichi

Proceedings for Annual Meeting of The Japanese Pharmacological Society   WCP2018 ( 0 )   PO2-3-12   2018

Ketamine suppresses the proliferation of rat C6 glioma cells.

Hideyuki Niwa, Ken-Ichi Furukawa, Kazuhiko Seya, Kazuki Hirota

ONCOLOGY LETTERS   2017.10

Simultaneous Measurement of Adenosine 3’,5’-Cyclic Monophosphate and Guanosine 3’,5’-Cyclic Monophosphate in Biological Samples.

Kazuhiko Seya, Shigeru Motomura, Tadaatsu Imaizumi, Ken-Ichi Furukawa

Hirosaki Medical Journal   2017.10

Ketamine suppresses the proliferation of rat C6 glioma cells.

Niwa H, Furukawa KI, Seya K, Hirota K

Oncology letters   14 ( 4 )   4911 - 4917   2017.10

Expression of CCL5 is induced by polyinosinic : polycytidylic acid in cultured hCMEC/D3 human brain microvascular endothelial cells.

Akine Arai, Hidemi Yoshida, Ryo Hayakari, Tomoh Matsumiya, Shogo Kawaguchi, Kazuhiko Seya, Hiroshi Tanak, Tadaatsu Imaizumi

CLINICAL AND EXPERIMENTAL NEUROIMMUNOLOGY   2017.9

Effects of Enflurane on Cardiac Autonomic Nervous Activity in Mice.

Yoshiki Ogata, Manabu Yonekura, Rouichi Yamaki, Chong Han, Tomonori Fujiwara, Kazuhiko Seya, Hidetoshi Niwa, Tetsuya Kushikata, Tadaatsu Imaizumi, Kazuyoshi Hirota, Hirofumi Tomita, Manabu Murakami

Hirosaki Medical Journal   2017.2

新生仔マウス初代培養心筋細胞の単離培養法

韓沖, 瀬谷和彦, 小潟佳輝, 野崎修平, 米倉学, 村上 学

Hirosaki Medical Journal   2017.2

Effects of enflurane on cardiac autonomic nervous activity in mice

Ogata Yoshiki, Hirota Kazuyoshi, Yamaki Rouichi, Han Chong, Fujiwara Tomonori, Seya Kazuhiko, Niwa Hidetoshi, Kushikata Tetsuya, Imaizumi Tadaatsu

Hirosaki Medical Journal   67 ( 2-4 )   153 - 157   2017

新生仔マウス初代培養心筋細胞の単離培養法

韓 沖, 瀬谷 和彦, 小潟 佳輝, 野崎 修平, 米倉 学, 村上 学

弘前医学   67 ( 2-4 )   147 - 152   2017

〈一般演題抄録〉大動脈弁異所性石灰化のキーレギュレーター： マトリックスグラタンパク質

于 在強, 千代谷 真理, 大徳 和之, 瀬谷 和彦, 古川 賢一, 福田 幾夫

弘前医学   67 ( 2-4 )   186   2017

Simultaneous measurement of adenosine 3’,5’-cyclic monophosphate and guanosine 3’,5’-cyclic monophosphate in biological samples.

瀬谷 和彦

Hirosaki Med J   68   52 - 61   2017

Simultaneous measurement of adenosine 3’,5’-cyclic monophosphate and guanosine 3’,5’-cyclic monophosphate in biological samples

Seya Kazuhiko, Motomura Shigeru, Imaizumi Tadaatsu, Furukawa Ken-Ichi

Hirosaki Medical Journal   68 ( 1 )   52 - 61   2017

1-Methyl-2-undecyl-4(1H)-quinolone, a derivative of quinolone alkaloid evocarpine, attenuates high phosphate-induced calcification of human aortic valve interstitial cells by inhibiting phosphate cotransporter PiT-1.

Seya K, Furukawa K, Chiyoya M, Yu Z, Kikuchi H, Daitoku K, Motomura S, Murakami M, Oshima Y, Fukuda I

Journal of pharmacological sciences   131 ( 1 )   51 - 7   2016.5

8-Methyltryptanthrin-induced differentiation of P19CL6 embryonal carcinoma cells into spontaneously beating cardiomyocyte-like cells.

Seya K, Yamaya A, Kamachi S, Murakami M, Kitahara H, Kawakami J, Okumura K, Murakami M, Motomura S, Furukawa K

Journal of natural products   77 ( 6 )   1413 - 9   2014.6

8‑Methyltryptanthrin-Induced Differentiation of P19CL6 Embryonal Carcinoma Cells into Spontaneously Beating Cardiomyocyte-like Cells

Kazuhiko Seya, Asako Yamaya, Sayuri Kamachi, Mana Murakami, Haruo Kitahara, Jun Kawakami, Ken Okumura, Manabu Murakami, Shigeru Motomura, and Ken-Ichi Furukawa

Journal of Natural Products   77   1413 - 1419   2014.6

CD34-negative mesenchymal stem-like cells may act as the cellular origin of human aortic valve calcification.

Nomura A, Seya K, Yu Z, Daitoku K, Motomura S, Murakami M, Fukuda I, Furukawa K

Biochemical and biophysical research communications   440 ( 4 )   780 - 5   2013.11

CD34-negative mesenchymal stem-like cells may act as the cellular origin of human aortic valve calcification

Anan Nomura, Kazuhiko Seya, Zaiqiang Yu, Kazuyuki Daitoku, Shigeru Motomura,Manabu Murakami, Ikuo Fukuda, Ken-Ichi Furukawa

Biochemical and Biophysical Research Communications   440 ( 780 )   785   2013.11

Cytosolic Ca2+-induced apoptosis in rat cardiomyocytes via mitochondrial NO-cGMP-protein kinase G pathway.

Kazuhiko Seya, Kyoichi Ono, Susumu Fujisawa, Ken Okumura, Shigeru Motomura, and Ken-Ichi Furukawa

Journal of Pharmacological and Experimental Therapy   2013.4

Cytosolic Ca2+-induced apoptosis in rat cardiomyocytes via mitochondrial NO-cGMP-protein kinase G pathway.

Seya K, Ono K, Fujisawa S, Okumura K, Motomura S, Furukawa K

The Journal of pharmacology and experimental therapeutics   344 ( 1 )   77 - 84   2013.1

Br-DIF-1 accelerates 1% dimethyl sulfoxide-induced cardiomyocyte differentiation from P19CL6 embryonic carcinoma cells

Kazuhiko Seya他

British Journal of Pharmacology   2012.4

Tumor Necrosis Factor-{alpha} Accelerates the Calcification of Human Aortic Valve Interstitial Cells Obtained from Patients with Calcific Aortic Valve Stenosis via the BMP2-Dlx5 Pathway.

「Zaiqiang Yu」「Kazuhiko Seya他」

Journal of Pharmacological and Experimental Therapy   2011.4

Tumor necrosis factor-α accelerates the calcification of human aortic valve interstitial cells obtained from patients with calcific aortic valve stenosis via the BMP2-Dlx5 pathway.

Yu Z, Seya K, Daitoku K, Motomura S, Fukuda I, Furukawa K

The Journal of pharmacology and experimental therapeutics   337 ( 1 )   16 - 23   2011.4

Contribution of bone morphogenetic protein-2 to aortic valve calcification in aged rat.

Kazuhiko Seya他

Journal of Pharmacological Sciences   2011.1

Contribution of Bone Morphogenetic Protein-2 to Aortic Valve Calcification in Aged Rat

Seya Kazuhiko, Yu Zaiqiang, Kanemaru Kouta, Daitoku Kazuyuki, Akemoto Yui, Shibuya Hiroyuki, Fukuda Ikuo, Okumura Ken, Motomura Shigeru, Furukawa Ken-Ichi

Journal of Pharmacological Sciences   115 ( 1 )   8 - 14   2011

Opposite effects of two resveratrol (trans-3,5,4'-trihydroxystilbene) tetramers, vitisin A and hopeaphenol, on apoptosis of myocytes isolated from adult rat heart.

Kazuhiko Seya, Kouta Kanemaru, Chiharu Sugimoto, Megumi Suzuki, Teruko Takeo, Shigeru Motomura, Haruo Kitahara, Masatake Niwa, Yoshiteru Oshima, Ken-Ichi Furukawa

Journal of Pharmacology and Experimental Therapy   328   90 - 98   2009.1

Opposite effects of two resveratrol (trans-3,5,4'-trihydroxystilbene) tetramers, vitisin A and hopeaphenol, on apoptosis of myocytes isolated from adult rat heart.

Seya K, Kanemaru K, Sugimoto C, Suzuki M, Takeo T, Motomura S, Kitahara H, Niwa M, Oshima Y, Furukawa K

The Journal of pharmacology and experimental therapeutics   328 ( 1 )   90 - 8   2009.1

Intracellular calcium ion regulates myocardial apoptosis induced by mitochondrial NO-cGMP pathway.

Kazuhiko Seya, Kyoichi Ono, Susumu Fujisawa, Shigeru Motomura, Ken-Ichi Furukawa

Journal of Molecular and Cellular Cardiology   45   S30 - S31   2008.12

高齢者にはどう聞こえる? (薬局のための 高齢者ケアガイドブック) -- (高齢者の特徴を知ろう)

瀬谷和彦

調剤と情報   14 ( 10 )   1183 - 1188   2008.9

Calcification of aortic smooth muscle cells isolated from spontaneously hypertensive rats.

Kouta Kanemaru, Kazuhiko Seya, Izumi Miki, Shigeru Motomura, Ken-Ichi Furukawa

Journal of Pharmacological Sciences   106   280 - 286   2008.2

Possible role of extracellular nucleotides in ectopic ossification of human spinal ligaments.

Toshikazu Sawada, Masaki Kishiya, Kouta Kanemaru, Kazuhiko Seya, Toru Yokoyama, Kazumasa Ueyama, Shigeru Motomura, Satoshi Toh, Ken-Ichi Furukawa

Journal of Pharmacological Sciences   106   152 - 161   2008.1

Calcification of Aortic Smooth Muscle Cells Isolated From Spontaneously Hypertensive Rats

Kanemaru Kouta, Seya Kazuhiko, Miki Izumi, Motomura Shigeru, Furukawa Ken-Ichi

Journal of Pharmacological Sciences   106 ( 2 )   280 - 286   2008

Possible Role of Extracellular Nucleotides in Ectopic Ossification of Human Spinal Ligaments

Sawada Toshitada, Kishiya Masaki, Kanemaru Kouta, Seya Kazuhiko, Yokoyama Toru, Ueyama Kazumasa, Motomura Shigeru, Toh Satoshi, Furukawa Ken-Ichi

Journal of Pharmacological Sciences   106 ( 1 )   152 - 161   2008

Assessment of the effects of L- and N-Type Ca²⁺ channel blocking drugs using canine isolated blood-perfused papillary muscle preparation.

Kazuyuki Daitoku, Kazuhiko Seya, Ken-Ichi Furukawa, Shigeru Motomura

The Tohoku Journal of Experimental Medicine   212   415 - 422   2007.8

Cardiac mitochondrial cGMP stimulates cytochrome c release.

Kazuhiko Seya, Shigeru Motomura, Ken-Ichi Furukawa

Clinical Science   112   113 - 121   2007.1

Cardiac mitochondrial cGMP stimulates cytochrome c release.

Seya K, Motomura S, Furukawa K

Clinical science (London, England : 1979)   112 ( 2 )   113 - 21   2007.1

Assessment of the Effects of L- and N-Type Ca2+ Channel Blocking Drugs Using Canine Blood-Perfused Papillary Muscle Preparations

Daitoku Kazuyuki, Seya Kazuhiko, Furukawa Ken-Ichi, Motomura Shigeru

The Tohoku Journal of Experimental Medicine   212 ( 4 )   415 - 422   2007

P-28 Scale and Peel of a Garlic as Functional Materials

Kitahara Haruo, Sugimoto Chiharu, Sasaki Narutoshi, Kanemaru Kouta, Togawa Kazuhiro, Handa Tomokazu, Harada Yukio, Sano Teruo, Seya Kazuhiko, Furukawa Ken-ichi, Motomura Shigeru, Ouchi Akihiko

Symposium on the Chemistry of Natural Products, symposium papers   48 ( 0 )   529 - 534   2006

Cardiac mitochondrial nitric oxide-cGMP pathway regulates myocardial apoptosis.

Kazuhiko Seya, Ken-Ichi Furukawa, Shigeru Motomura

Mitochondria and Life 2005   110 - 110   2005.12

Nifedipine enhances cGMP production through the activation of soluble guanylyl cyclase in rat ventricular papillary muscle.

Kazuhiko Seya, Ken-Ichi Furukawa, Kazuhiko Yoshida, Reina Narita, Shigeru Motomura

Journal of Pharmacy and Pharmacology   57   511 - 514   2005.4

Nifedipine enhances cGMP production through the activation of soluble guanylyl cyclase in rat ventricular papillary muscle.

Seya K, Furukawa K, Yoshida K, Narita R, Motomura S

The Journal of pharmacy and pharmacology   57 ( 4 )   511 - 4   2005.4

心筋ミトコンドリア一酸化窒素-cGMP経路によるアポトーシス誘導機構の解明と創薬

瀬谷 和彦, 古川 賢一, 元村 成

日本薬理学雑誌 : FOLIA PHARMACOLOGICA JAPONICA   124   83P - 84P   2004.11

Role of Corticotropin-Releasing Factor Receptor Type 2βin Urocortin-Induced Vasodilation of Rat Aortas

MIKI Izumi, SEYA Kazuhiko, MOTOMURA Shigeru, FURUKAWA Ken-Ichi

Journal of pharmacological sciences   96 ( 2 )   170 - 176   2004.10

Role of Corticotropin Releasing Factor Receptor Type 2beta in Urocortin-Induced Vasodilation of Rat Aortas.

Izumi Miki, Kazuhiko Seya, Shigeru Motomura, Ken-Ichi Furukawa

Journal of Pharmacological Sciences   96   170 - 176   2004.10

Regulation of cytochrome c release via mitochondrial NO-cGMP pathway in rat cardiac myocytes.

Kazuhiko Seya, Ken-Ichi Furukawa, Shigeru Motomura

Biochimica et Biophysica Acta, Euromit6 Abstract book   69 - 69   2004.7

For the realization of comfortable medical treatments for hard of hearing and late-deafened people in Japan

Kazuhiko Seya, Tadashi Takaoka

THE PAPERS AND PRESENTATIONS OF THE 7TH IFHOH WORLD CONGRES   2004.7

Gene expression and functional activity of sodium/calcium exchanger enhanced in vascular smooth muscle cells of spontaneously hypertensive rats.

Satoshi Taniguchi S, Ken-Ichi Furukawa, Satoshi Sasamura, Yasushi Ohizumi, Kazuhiko Seya, Shigeru Motomura

Journal of Cardiovascular Pharmacology   43   629 - 637   2004.5

Gene expression and functional activity of sodium/calcium exchanger enhanced in vascular smooth muscle cells of spontaneously hypertensive rats.

Taniguchi S, Furukawa K, Sasamura S, Ohizumi Y, Seya K, Motomura S

Journal of cardiovascular pharmacology   43 ( 5 )   629 - 37   2004.5

Role of Corticotropin-Releasing Factor Receptor Type 2.BETA. in Urocortin-Induced Vasodilation of Rat Aortas

Miki Izumi, Seya Kazuhiko, Motomura Shigeru, Furukawa Ken-Ichi

Journal of Pharmacological Sciences   96 ( 2 )   170 - 176   2004

Endothelium-dependent vasodilatory effect of vitisin C, a novel plant oligostilbene from Vitis Plants (Vitaceae) in rabbit aorta

Kazuhiko Seya, Ken-Ichi Furukawa, Satoshi Taniguchi, Genji Kodzuka, Yoshiteru Oshima, Masatake Niwa, and Shigeru Motomura

Clinical Science   105   73 - 79   2003.7

Endothelium-dependent vasodilatory effect of vitisin C, a novel plant oligostilbene from Vitis plants (Vitaceae), in rabbit aorta.

Seya K, Furukawa K, Taniguchi S, Kodzuka G, Oshima Y, Niwa M, Motomura S

Clinical science (London, England : 1979)   105 ( 1 )   73 - 9   2003.7

Chemiluminescent Assay for Phosphatidylcholine Hydroperoxide.

SEYA Kazuhiko, OHKOHCHI Nobuhiro, SHIBUYA Hiroshi, SATOMI Susumu, MOTOMURA Shigeru

Analytical Sciences   13 ( 2 )   311 - 314   1997

Pharmacological properties of pteleprenine, a quinoline alkaloid from <I>Orixa japonica</I> (Rutaceae), in guinea pig ileum and canine left atrium

MURATA Kiyoshi, SEYA Kazuhiko, MIKI Izumi, JUNKE Hisae, MOTOMURA Shigeru, OSHIMA Yoshiteru

Folia Pharmacologica Japonica   110 ( supplement )   148 - 152   1997

A chemiluminescent assay for hydroperoxide level of phosphatidylcholine hydroperoxide fraction purified by two Sep-Pak cartridges in biological samples

K Seya, N Ohkohchi, H Shibuya, M Satoh, K Oikawa, T Fukumori, S Satomi, S Motomura

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS   23 ( 2-3 )   515 - 520   2000.8

Novel acyl alpha-pyronoids, dictyopyrone A, B, and C, from Dictyostelium cellular slime molds

Y Takaya, H Kikuchi, Y Terui, J Komiya, KI Furukawa, K Seya, S Motomura, A Ito, Y Oshima

JOURNAL OF ORGANIC CHEMISTRY   65 ( 4 )   985 - 989   2000.2

Norepinephrine measurement in the isolated, blood-perfused papillary muscle of the dog by using ex vivo microdialysis

K Seya, K Daitoku, S Motomura

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS   42 ( 3 )   149 - 155   1999.11

A fluorometric assay for cyclic guanosine 3 ',5 '-monophosphate incorporating a Sep-Pak cartridge and enzymatic cycling

K Seya, KI Furukawa, S Motomura

ANALYTICAL BIOCHEMISTRY   272 ( 2 )   243 - 249   1999.8

Fragility of the electron transport chain and superoxide generation in mitochondria of the liver graft after cold ischemia

N Ohkohchi, T Endoh, K Oikawa, K Seya, S Satomi

TRANSPLANTATION   67 ( 8 )   1173 - 1177   1999.4

Kupffer cells generate superoxide anions and modulate lipid peroxidation and mitochondrial proton ATP-ASE activity in the perfused rat liver after cold preservation

H Shibuya, N Ohkohchi, K Seya, S Satomi

TRANSPLANTATION PROCEEDINGS   29 ( 1-2 )   1328 - 1330   1997.2

PHOTO-OXIDATION OF L-TYROSINE, AN EFFICIENT 1,4-CHIRALITY TRANSFER-REACTION

K ENDO, K SEYA, H HIKINO

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS   ( 14 )   934 - 935   1988.7