Updated on 2024/03/25

写真a

 
SAKURABA Hirotake
 
Affiliation
Graduate School of Medicine Medical Science Course F

Degree

  • 博士(医学)

Research Areas

  • Life Science / Connective tissue disease and allergy

  • Life Science / Gastroenterology

  • Life Science / Immunology

Professional Memberships

  • 日本消化管学会

  • 日本カプセル内視鏡学会

  • 日本大腸肛門病学会

  • 日本臨床免疫学会

  • 日本細菌学会

  • 消化器免疫学会

  • 日本内科学会

  • 日本消化器内視鏡学会

  • 日本リウマチ学会

  • 日本消化器病学会

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Papers

  • Cyclosporine protects from intestinal epithelial injury by modulating butyrate uptake via upregulation of membrane monocarboxylate transporter 1 levels

    Ota S, Sakuraba H

    Biochem Biophys Rep   2020.12

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  • Anxiety and behavioral changes in Japanese patients with inflammatory bowel disease due to COVID-19 pandemic: a national survey.

    Nakase H, Wagatsuma K, Nojima M, Matsumoto T, Matsuura M, Iijima H, Matsuoka K, Ohmiya N, Ishihara S, Hirai F, Takeuchi K, Tamura S, Kinjo F, Ueno N, Naganuma M, Watanabe K, Moroi R, Nishimata N, Motoya S, Kurahara K, Takahashi S, Maemoto A, Sakuraba H, Saruta M, Tominaga K, Hisabe T, Tanaka H, Terai S, Hiraoka S, Takedomi H, Narimatsu K, Endo K, Nakamura M, Hisamatsu T

    Journal of gastroenterology   58 ( 3 )   205 - 216   2023.3

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  • The new 222-nm far ultraviolet-C lowers bacterial contamination to endoscopists during esophagogastroduodenoscopy.

    Fukutoku Y, Kikuchi H, Hoshi K, Narita K, Asari T, Miyazawa K, Sawada Y, Hayamizu S, Tatsuta T, Oota S, Hasui K, Hiraga H, Chinda D, Mikami T, Subsomwong P, Asano K, Yamane K, Ogawa Y, Sasaki M, Koi T, Ohashi H, Nakane A, Sakuraba H

    DEN open   4 ( 1 )   e292   2024.4

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  • Impact of the COVID-19 pandemic on the performance of endoscopy in the Tohoku region of Japan.

    Iijima K, Matsuhashi T, Shimodaira Y, Mikami T, Yoshimura T, Yanai S, Kudara N, Tsuji T, Matsushita HO, Watanabe H, Koike T, Kato K, Abe Y, Shirahata N, Hikichi T, Katakura K, Kono K, Sakuraba H, Ueno Y, Ohira H, Masamune A, Matsumoto T, Fukuda S, Japan Gastroenterological Endoscopy Society‐Tohoku

    DEN open   4 ( 1 )   e249   2024.4

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  • A Cohort Study of the Influence of the 12-Component Modified Japanese Diet Index on Oral and Gut Microbiota in the Japanese General Population.

    Sato S, Chinda D, Iino C, Sawada K, Mikami T, Nakaji S, Sakuraba H, Fukuda S

    Nutrients   16 ( 4 )   2024.2

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  • A Logistic Regression Model for Predicting the Risk of Subsequent Surgery among Patients with Newly Diagnosed Crohn's Disease Using a Brute Force Method.

    Ogasawara K, Hiraga H, Sasaki Y, Hiraga N, Higuchi N, Hasui K, Ota S, Maeda T, Murai Y, Tatsuta T, Kikuchi H, Chinda D, Mikami T, Matsuzaka M, Sakuraba H, Fukuda S

    Diagnostics (Basel, Switzerland)   13 ( 23 )   2023.12

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  • Influence of CYP3A5 and ABCB1 polymorphisms on the pharmacokinetics of vincristine in adult patients receiving CHOP therapy.

    Nakagawa J, Takahata T, Chen Y, Saito K, Kamata K, Tachita T, Yamashita S, Saito K, Ueno K, Sato A, Sakuraba H, Niioka T

    Cancer chemotherapy and pharmacology   92 ( 5 )   391 - 398   2023.11

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  • Trajectory analyses to identify persistently low responders to COVID-19 vaccination in patients with inflammatory bowel disease: a prospective multicentre controlled study, J-COMBAT.

    Watanabe K, Nojima M, Nakase H, Sato T, Matsuura M, Aoyama N, Kobayashi T, Sakuraba H, Nishishita M, Yokoyama K, Esaki M, Hirai F, Nagahori M, Nanjo S, Omori T, Tanida S, Yokoyama Y, Moriya K, Maemoto A, Handa O, Ohmiya N, Tsuchiya K, Shinzaki S, Kato S, Uraoka T, Tanaka H, Takatsu N, Nishida A, Umeno J, Nakamura M, Mishima Y, Fujiya M, Tsuchida K, Hiraoka S, Okabe M, Toyonaga T, Matsuoka K, Andoh A, Hirota Y, Hisamatsu T, J-COMBAT study group

    Journal of gastroenterology   58 ( 10 )   1015 - 1029   2023.10

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  • Assessment of the Physical Invasiveness of Peroral Endoscopic Myotomy during the Perioperative Period Based on Changes in Energy Metabolism.

    Chinda D, Shimoyama T, Fujiwara S, Kaizuka M, Yasuda K, Akitaya K, Arai T, Sawada Y, Hayamizu S, Tatsuta T, Kikuchi H, Yanagimachi M, Mikami T, Sakuraba H, Fukuda S

    Metabolites   13 ( 9 )   2023.8

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  • Vitamin A Promotes the Fusion of Autophagolysosomes and Prevents Excessive Inflammasome Activation in Dextran Sulfate Sodium-Induced Colitis.

    Hiraga H, Chinda D, Maeda T, Murai Y, Ogasawara K, Muramoto R, Ota S, Hasui K, Sakuraba H, Ishiguro Y, Yoshida S, Asano K, Nakane A, Fukuda S

    International journal of molecular sciences   24 ( 10 )   2023.5

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  • A trial deep learning-based model for four-class histologic classification of colonic tumor from narrow band imaging.

    Shimizu T, Sasaki Y, Ito K, Matsuzaka M, Sakuraba H, Fukuda S

    Scientific reports   13 ( 1 )   7510   2023.5

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  • Bacterial exposure risk to the endoscopist's face while performing endoscopy.

    Hoshi K, Kikuchi H, Narita K, Fukutoku Y, Asari T, Miyazawa K, Murai Y, Sawada Y, Tatsuta T, Hasui K, Hiraga H, Chinda D, Mikami T, Subsomwong P, Asano K, Nakane A, Fukuda S, Sakuraba H

    DEN open   3 ( 1 )   e209   2023.4

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  • Polygonum tinctorium leaf extract ameliorates high-fat diet-induced intestinal epithelial damage in mice.

    Kawaguchi S, Sakuraba H, Kikuchi H, Matsuki K, Hayashi Y, Ding J, Tanaka Y, Seya K, Matsumiya T, Hiraga H, Fukuda S, Sasaki K, Imaizumi T

    Experimental and therapeutic medicine   25 ( 3 )   112   2023.3

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  • Evaluation of Crohn's Disease Small-Bowel Mucosal Healing Using Capsule Endoscopy and Usefulness of Leucine-Rich α2-Glycoprotein.

    Hiraga H, Chinda D, Hasui K, Murai Y, Maeda T, Higuchi N, Ogasawara K, Kudo S, Sawada Y, Tatsuta T, Kikuchi H, Ebina M, Hiraga N, Mikami T, Sakuraba H, Fukuda S

    Diagnostics (Basel, Switzerland)   13 ( 4 )   2023.2

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  • Association between reactive oxygen species production in neutrophils and liver fibrosis in the general population

    Sato Satoshi, Nakaji Shigeyuki, Sawada Kaori, Akimoto Naoki, Tateda Tetsuyuki, Kaizuka Masatoshi, Sasada Takafumi, Nomiya Hiroki, Igarashi Go, Iino Chikara, Chinda Daisuke, Mikami Tatsuya, Sakuraba Hirotake, Fukuda Shinsaku

    Journal of Clinical Biochemistry and Nutrition   73 ( 3 )   214 - 220   2023

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  • Tryptanthrin attenuates TLR3-mediated STAT1 activation in THP-1 cells.

    Numao N, Kawaguchi S, Ding J, Karasawa T, Seya K, Matsumiya T, Kikuchi H, Sakuraba H, Fukuda S, Imaizumi T

    Immunologic research   70 ( 5 )   688 - 697   2022.10

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  • A Cohort Study of the Effects of Daily-Diet Water-Soluble Dietary Fiber on Butyric Acid-Producing Gut Microbiota in Middle-Aged and Older Adults in a Rural Region.

    Sato S, Chinda D, Shimoyama T, Iino C, Kudo S, Sawada K, Mikami T, Nakaji S, Sakuraba H, Fukuda S

    Microorganisms   10 ( 9 )   2022.9

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  • Clinical Features of Fecal Immunochemical Test-Negative Colorectal Lesions based on Colorectal Cancer Screening among Asymptomatic Participants in Their 50s.

    Suto S, Matsuzaka M, Sawaya M, Sakuraba H, Mikami T, Matsuda T, Fujii T, Saito Y, Hotta K, Ikematsu H, Hanabata N, Saito H, Yoshida S, Fukuda S

    Asian Pacific journal of cancer prevention : APJCP   23 ( 7 )   2325 - 2332   2022.7

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  • Tacrolimus Up-regulates Expression of TGFβ Receptor Type II via ERK, Providing Protection Against Intestinal Epithelial Injury.

    Satake M, Sakuraba H, Hiraga H, Yoshida S, Akemoto Y, Ota S, Murai Y, Hasui K, Kawaguchi S, Kikuchi H, Fukuda S

    In vivo (Athens, Greece)   36 ( 4 )   1684 - 1693   2022.7

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  • Reduced Equol Production and Gut Microbiota Features in Men With Lean Nonalcoholic Fatty Liver Disease.

    Iino C, Endo T, Iino K, Tateda T, Sato S, Igarashi G, Mikami K, Sakuraba H, Yokoyama Y, Nakaji S, Fukuda S

    American journal of men's health   16 ( 4 )   15579883221115598   2022.7

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  • Polygonum tinctorium leaves suppress sodium dextran sulfate-induced colitis through interleukin-10-related pathway.

    Asari T, Kikuchi H, Kawaguchi S, Sakuraba H, Yoshida S, Akemoto Y, Maeda T, Shinji O, Murai Y, Higuchi N, Hoshi K, Fukutoku Y, Hiraga H, Sasaki K, Fukuda S

    Biochemistry and biophysics reports   30   101272   2022.7

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  • 増刊号 図説「胃と腸」画像診断用語集2022 分類・定義 腸 潰瘍性大腸炎の内視鏡的重症度分類

    櫻庭 裕丈, 福田 眞作

    胃と腸   57 ( 5 )   708 - 709   2022.5

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    CiNii Research

  • Influence of Esophageal Endoscopic Submucosal Dissection on the Changes of Energy Metabolism during the Perioperative Period.

    Kudo S, Chinda D, Shimoyama T, Yasuda K, Akitaya K, Arai T, Miyazawa K, Hayamizu S, Yanagimachi M, Tsukamoto T, Kaizuka M, Sawada Y, Tatsuta T, Hasui K, Kikuchi H, Hiraga H, Sakuraba H, Mikami T, Fukuda S

    Cancers   14 ( 8 )   2022.4

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  • Endoscopic and histopathologic features of Anti-PD-1-related collagenous colitis.

    Kikuchi H, Sakuraba H, Akemoto Y, Hosoi K, Murai Y, Hoshi K, Fukutoku Y, Asari T, Sawada Y, Hasui K, Tatsuta T, Hiraga H, Chinda D, Mikami T, Fukuda S

    DEN open   2 ( 1 )   e92   2022.4

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  • Impact of polymorphisms of pharmacokinetics-related genes and the inflammatory response on the metabolism of voriconazole.

    Aiuchi N, Nakagawa J, Sakuraba H, Takahata T, Kamata K, Saito N, Ueno K, Ishiyama M, Yamagata K, Kayaba H, Niioka T

    Pharmacology research & perspectives   10 ( 2 )   e00935   2022.4

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  • Spatial distribution of live gut microbiota and bile acid metabolism in various parts of human large intestine

    Chinda D, Takada T, Mikami T, Shimizu K, Oana K, Arai T, Akitaya K, Sakuraba H, Katto M, Nagara Y, Makino H, Fujii D, Oishi K, Fukuda S

    Sci Rep   2022.3

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  • Impact of polymorphisms of pharmacokinetics-related genes and the inflammatory response on the metabolism of voriconazole

    Aiuchi N, Nakagawa J, Sakuraba H, Takahata T, Kamata K, Saito N, Ueno K, Ishiyama M, Yamagata K, Kayaba H, Niioka T

    Pharmacol Res Perspect   2022.1

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  • Automated evaluation of colon capsule endoscopic severity of ulcerative colitis using ResNet50.

    Higuchi N, Hiraga H, Sasaki Y, Hiraga N, Igarashi S, Hasui K, Ogasawara K, Maeda T, Murai Y, Tatsuta T, Kikuchi H, Chinda D, Mikami T, Matsuzaka M, Sakuraba H, Fukuda S

    PloS one   17 ( 6 )   e0269728   2022

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  • Evaluation of metabolic dysfunction-associated fatty liver disease using FibroScan, diet, and microbiota: A large cross-sectional study.

    Tateda T, Iino C, Sasada T, Sato S, Igarashi G, Kawaguchi S, Mikami K, Endo T, Sawada K, Mikami T, Fukuda S, Nakaji S, Sakuraba H

    PloS one   17 ( 11 )   e0277930   2022

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  • Association of serum creatinine-to-cystatin C ratio with skeletal muscle mass and strength in nonalcoholic fatty liver disease in the Iwaki Health Promotion Project

    2. Mikami K, Endo T, Sawada N, Igarashi G, Kimura M, Hasegawa T, Iino C, Sawada K, Ando M, Nakaji S, Matsuzaka M, Sakuraba H, Fukuda S

    J Clin Biochem Nutr   2021.12

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  • Active and passive smoking and risk of ulcerative colitis: A case-control study in Japan

    1. Nishikawa A, Tanaka K, Miyake Y, Nagata C, Furukawa S, Andoh A, Yokoyama T, Yoshimura N, Mori K, Ninomiya T, Yamamoto Y, Takeshita E, Ikeda Y, Saito M, Ohashi K, Imaeda H, Kakimoto K, Higuchi K, Nunoi H, Mizukami Y, Suzuki S, Hiraoka S, Okada H, Kawasaki K, Higashiyama M, Hokari R, Miura H, Miyake T, Kumagi T, Kato H, Hato N, Sayama K, Hiasa Y and Japan Ulcerative Colitis Study Group (Sakuraba H)

    J Gastroenterol Hepatol   2021.12

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  • Macrophages Express Melanoma Differentiation-Associated Gene 5 in Nonalcoholic Steatohepatitis

    Kawaguchi S, Sakuraba H, Horiuchi M, Ding J, Matsumiya T, Seya K, Iino C, Endo T, Kikuchi H, Yoshida S, Hiraga H, Fukuda S, Imaizumi T

    Inflammation   2021.12

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  • Leptomeningeal andintraventricular myelomatosis manifesting an aggressive form of communicating hydrocephalus

    Miki Y, Kamata K, Akemoto Y, Tsushima F, Sakuraba H, Yamagata K, Fukuda S, Wakabayashi K

    Neuropathology   2021.1

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  • Genetic background of mesalamine-induced fever and diarrhea in Japanese patients with inflammatory bowel disease

    Suzuki K, Kakuta Y, Naito T, Takagawa T, Hanai H, Araki H, Sasaki Y, Sakuraba H, Sasaki M, Hisamatsu T, Motoya S, Matsumoto T, Onodera M, Ishiguro Y, Nakase H, Andoh A, Hiraoka S, Shinozaki M, Fujii T, Katsurada T, Kobayashi T, Fujiya M, Otsuka T, Oshima N, Suzuki Y, Sato Y, Hokari R, Noguchi M, Ohta Y, Matsuura M, Kawai Y, Tokunaga K, Nagasaki M, Kudo H, Minegishi N, Okamoto D, Shimoyama Y, Moroi R, Kuroha M, Shiga H, Li D, P.B McGovern D, Kinouchi Y, Masamune A

    Inflamm Bowel Dis   2021.1

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  • Long-term efficacy and tolerability of dose-adjusted thiopurine treatment in maintaining remission in inflammatory bowel disease patients with NUDT15 heterozygosity

    Maeda T, Sakuraba H, Hiraga H, Yoshida S, Kakuta Y, Kikuchi H, Kawaguchi S, Hasui K, Tatsuta T, Chinda D, Mikami T, Fukuda S

    Intest Res   2021.1

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  • Tryptanthrin suppresses double-stranded RNA-induced CXCL10 expression via inhibiting the phosphorylation of STAT1 in human umbilical vein endothelial cells

    Kawaguchi S, Sakuraba H, Kikuchi H, Numao N, Asari T, Hiraga H, Ding J, Matsumiya T, Seya K, Fukuda S, Imaizumi T

    Mol Immunol   2021.1

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  • Dietary intake of vegetables, fruit, and antioxidants and risk of ulcerative colitis: a case-control study in Japan

    Miyake Y, Tanaka K, Nagata C, Furukawa S, Andoh A, Yokoyama T, Yoshimura N, Mori K, Ninomiya T, YamamotoY, Takeshita E, Ikeda Y, Saito M, Ohashi K, Imaeda H, Kakimoto K, Higuchi K, Nunoi H, Mizukami Y, Suzuki S, Hiraoka S, Okada H, Kawasaki K, Higashiyama M, Hokari R, Miura H, Miyake T, Kumagi T, Kato H, Hato N, Sayama K, Hiasa Y, and Japan Ulcerative Colitis Study Group (Sakuraba H).

    Nutrition   2021

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  • 5. Anatomical classification of upper gastrointestinal organs under various image capture conditions using AlexNet

    Igarashi S, Sasaki Y, Mikami T, Sakuraba H, Fukuda S

    Comput Biol Med   2020.10

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  • Anatomical classification of upper gastrointestinal organs under various image capture conditions using AlexNet.

    Igarashi S, Sasaki Y, Mikami T, Sakuraba H, Fukuda S

    Computers in biology and medicine   124   103950   2020.9

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  • A nationwide, multi-center, retrospective study of symptomatic small bowel stricture in patients with Crohn's disease.

    Shigeki Bamba, Ryosuke Sakemi, Toshimitsu Fujii, Teruyuki Takeda, Shin Fujioka, Kento Takenaka, Hiroki Kitamoto, Shotaro Umezawa, Hirotake Sakuraba, Toshihiro Inokuchi, Norimasa Fukata, Shinta Mizuno, Masaki Yamashita, Shinichiro Shinzaki, Hiroki Tanaka, Hidetoshi Takedatsu, Ryo Ozaki, Kei Moriya, Manabu Ishii, Tetsu Kinjo, Keiji Ozeki, Makoto Ooi, Ryohei Hayashi, Kazuki Kakimoto, Yuichi Shimodate, Kazuya Kitamura, Akihiro Yamada, Akira Sonoda, Yu Nishida, Kyouko Yoshioka, Shinya Ashizuka, Fumiaki Takahashi, Toshio Shimokawa, Taku Kobayashi, Akira Andoh, Toshifumi Hibi

    Journal of gastroenterology   2020.1

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  • Case report of lanthanum deposition in the esophagus.

    Tetsuya Tatsuta, Tatsuya Mikami, Daisuke Chinda, Kazuki Akitaya, Shohei Igarashi, Keisuke Hasui, Hidezumi Kikuchi, Hiroto Hiraga, Manabu Sawaya, Hirotake Sakuraba, Tadashi Shimoyama, Tosihiro Haga, Hiroshi Kijima, Shinsaku Fukuda

    Clinical journal of gastroenterology   2019.12

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  • Diagnostic approach for patients with unidentified fever according to the classical criteria of fever of unknown origin in the field of autoimmune disorders.

    Rina Watanabe, Hirotake Sakuraba, Hiroto Hiraga, Dai Kishida, Shinji Ota, Keisuke Hasui, Hidezumi Kikuchi, Yui Akemoto, Nahoko Tanaka, Takato Maeda, Yasuhisa Murai, Shukuko Yoshida, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Yoh Ishiguro, Shinsaku Fukuda

    Immunological medicine   42 ( 4 )   176 - 184   2019.12

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  • Melanoma Differentiation-Associated Gene 5 Positively Modulates TNF-α-Induced CXCL10 Expression in Cultured HuH-7 and HLE Cells.

    Shogo Kawaguchi, Hirotake Sakuraba, Toshihiro Haga, Tomoh Matsumiya, Kazuhiko Seya, Tetsu Endo, Naoya Sawada, Chikara Iino, Hidezumi Kikuchi, Hiroto Hiraga, Shinsaku Fukuda, Tadaatsu Imaizumi

    Inflammation   42 ( 6 )   2095 - 2104   2019.12

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  • Usefulness of serum opsonic activity measured by chemiluminescence method to assess the invasiveness of colorectal endoscopic mucosal dissection.

    Daisuke Chinda, Tadashi Shimoyama, Tetsu Arai, Kaori Sawada, Kazuki Akitaya, Sae Kudo, Kohei Yasuda, Kuniaki Miyazawa, Naoki Akimoto, Satoshi Sato, Shiro Hayamizu, Tetsuya Tatsuta, Hidezumi Kikuchi, Hiroto Hiraga, Manabu Sawaya, Hirotake Sakuraba, Tatsuya Mikami, Shigeyuki Nakaji, Shinsaku Fukuda

    Free radical research   1 - 8   2019.10

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  • Withdrawal of thiopurines in Crohn's disease treated with scheduled adalimumab maintenance: a prospective randomised clinical trial (DIAMOND2).

    Tadakazu Hisamatsu, Shingo Kato, Reiko Kunisaki, Minoru Matsuura, Masakazu Nagahori, Satoshi Motoya, Motohiro Esaki, Norimasa Fukata, Satoko Inoue, Takeshi Sugaya, Hirotake Sakuraba, Fumihito Hirai, Kenji Watanabe, Takanori Kanai, Makoto Naganuma, Hiroshi Nakase, Yasuo Suzuki, Mamoru Watanabe, Toshifumi Hibi, Masanori Nojima, Takayuki Matsumoto,

    Journal of gastroenterology   54 ( 10 )   860 - 870   2019.10

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  • Long-term maintenance of the mucosal healing induced by azacitidine therapy in a patient with intestinal Behçet's-like disease accompanied with myelodysplastic syndrome involving trisomy 8.

    Nahoko Tanaka, Hirotake Sakuraba, Hiroto Hiraga, Ko Mayama, Hidezumi Kikuchi, Dai Kishida, Yui Akemoto, Keisuke Hasui, Shinji Ota, Rina Watanabe, Yasuhisa Murai, Takato Maeda, Kosuke Kamata, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Kazufumi Yamagata, Yoh Ishiguro, Masanori Tanaka, Shinsaku Fukuda

    Immunological medicine   42 ( 3 )   135 - 141   2019.9

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  • A case of celiac disease with type I enteropathy-associated T-cell lymphoma in a Japanese male patient.

    Hiroto Hiraga, Hirotake Sakuraba, Nahoko Tanaka, Rina Watanabe, Yui Akemoto, Shinji Ota, Hidezumi Kikuchi, Manabu Sawaya, Noriko Hiraga, Daisuke Chinda, Norihiro Hanabata, Tatsuya Mikami, Tadashi Shimoyama, Takenori Takahata, Masanori Tanaka, Shinsaku Fukuda

    Immunological medicine   42 ( 3 )   142 - 147   2019.9

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  • Influence of Helicobacter pylori Infection and Atrophic Gastritis on the Gut Microbiota in a Japanese Population.

    Chikara Iino, Tadashi Shimoyama, Daisuke Chinda, Hirotake Sakuraba, Shinsaku Fukuda, Shigeyuki Nakaji

    Digestion   1 - 11   2019.8

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  • Lifestyle Factors Rather Than Helicobacter pylori Infection or Estradiol Level are Associated With Osteopenia in Japanese Men.

    Daisuke Chinda, Tadashi Shimoyama, Kaori Sawada, Chikara Iino, Hirotake Sakuraba, Shigeyuki Nakaji, Shinsaku Fukuda

    American journal of men's health   13 ( 2 )   1557988319848219 - 1557988319848219   2019.3

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    Language:English   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Influence of gastric endoscopic submucosal dissection on serum opsonic activity measured by chemiluminescence.

    Tetsu Arai, Daisuke Chinda, Tadashi Shimoyama, Kaori Sawada, Kazuki Akitaya, Kuniaki Miyazawa, Naoki Akimoto, Satoshi Sato, Shiro Hayamizu, Tetsuya Tatsuta, Hidezumi Kikuchi, Hiroto Hiraga, Manabu Sawaya, Hirotake Sakuraba, Tatsuya Mikami, Shigeyuki Nakaji, Shinsaku Fukuda

    Journal of clinical biochemistry and nutrition   64 ( 2 )   180 - 185   2019.3

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  • A case of nivolumab-associated colitis, which relapsed after mucosal healing and was then successfully treated with mesalazine.

    Hidezumi Kikuchi, Hirotake Sakuraba, Yui Akemoto, Yasuhisa Murai, Yukari Fukutoku, Taka Asari, Tetsuya Tatsuta, Keisuke Hasui, Hiroto Hiraga, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Masanori Tanaka, Shinsaku Fukuda

    Immunological medicine   42 ( 1 )   39 - 44   2019.3

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  • Daidzein Intake Is Associated with Equol Producing Status through an Increase in the Intestinal Bacteria Responsible for Equol Production.

    Iino C, Shimoyama T, Iino K, Yokoyama Y, Chinda D, Sakuraba H, Fukuda S, Nakaji S

    Nutrients   2019.2

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  • Gastric Focal Neutrophil Infiltration and Wide Duodenal Gastric Foveolar Metaplasia Are Histologic Discriminative Markers for Crohn's Disease and Behçet's Disease

    Akemoto Y, Sakuraba H, et al

    Digestion   2018.12

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  • Successful treatment with tacrolimus of refractory Pyoderma Gangrenosum with pouchitis after restorative proctocolectomy for ulcerative colitis

    Satake M, Sakuraba H, et al

    Immunological Medicine   2018.11

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  • MENDEL study group. NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study

    2. Kakuta Y, Kawai Y, Okamoto D, Takagawa T, Ikeya K, Sakuraba H, et al

    J Gastroenterol   2018.6

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  • 5. Mikami K, Endo T, Sawada N, Igarashi G, Kimura M, Sakuraba H, Fukuda S. Inhibition of Systemic Hyaluronan Synthesis Exacerbates Murine Hepatic Carcinogenesis

    Mikami K, Endo T, Sawada N, Igarashi G, Kimura M, Sakuraba H, Fukuda S

    In Vivo   2018.4

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  • Clinical and Pharmacokinetic Factors Associated With Adalimumab-Induced Mucosal Healing in Patients With Crohn's Disease

    6. Watanabe K, Matsumoto T, Hisamatsu T et al

    Clin Gastroenterol Hepatol   2018.4

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  • Vimentin-positive gastric adenocarcinoma arising in a hyperplastic polyp

    Kawaguchi S, Yoshimura T, Sakuraba H et al

    Clin J Gastroenterol   2018.2

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  • 不明熱症例における心因性発熱の検討

    櫻庭美耶子、佐藤研、櫻庭裕丈、平賀寛人、佐竹 立、福田眞作

    日本心療内科学会誌   2018.2

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  • 心不全, 呼吸不全, 急性腎障害を合併した高齢発症全身性硬化症の1例

    櫻庭裕丈、金澤 洋、田坂定智、深掘耕平、宮崎真理子、鬼島 宏、玉井佳子、北川 泉、珍田大輔、大沢 弘

    日本内科学会雑誌   2017.11

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  • Significance of measurement of serum trough level and anti-drug antibody of adalimumab as personalised pharmacokinetics in patients with Crohn's disease: a subanalysis of the DIAMOND trial

    9. Nakase H, Motoya S, Matsumoto T et al

    Aliment Pharmacol Ther   2017.9

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  • Successful adalimumab treatment and usefulness of capsule endoscopy for gut inflammation concomitant with ankylosing spondylitis

    Shinji Ota, Hirotake Sakuraba, Hiroto Hiraga, Keisuke Hasui, Miwa Satake,Norihiro Hanabata, Yui Akemoto, Rina Watanabe, Nahoko Tanaka, Yoh Ishiguro, Masanori Tanaka, Shinsaku Fukuda

    Mod Rheumatol   2017.2

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  • 早期胃癌に対する内視鏡的粘膜下層剥離術の周術期におけるエネルギー代謝の検討

    珍田大輔、速水史郎、柳町幸、塚本利昭、新井徹、宮澤邦昭、菊池英純、平賀寛人、澤谷学、櫻庭裕丈、三上達也、下山克、福田眞作

    消化と吸収   2016.9

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  • Capsule Endoscopy for Differentiating Early Crohn's Disease from Behçet's

    Miwa Satake, Hirotake Sakuraba, Hiroto Hiraga, Norihiro Hanabata, Noriko Hiraga, Keisuke Hasui, Shinji Ota, Yui Akemoto, Tatsuya Mikami, Yoh Ishiguro, Shinsaku Fukuda

    Journal of Inflammatory Bowel Disease   2016.6

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  • Clinical and structural remission rates increased annually and radiographic progression was continuously inhibited during a 3-year administration of tocilizumab in patients with rheumatoid arthritis: A multi-center, prospective cohort study by the Michinoku Tocilizumab Study Group.

    Hirabayashi Y, Munakata Y, Miyata M, Urata Y, Saito K, Okuno H, Yoshida M, Kodera T, Watanabe R, Miyamoto S, Ishii T, Nakazawa S, Takemori H, Ando T, Kanno T, Komagamine M, Kato I, Takahashi Y, Komatsuda A, Endo K, Murai C, Takakubo Y, Miura T, Sato Y, Ichikawa K, Konta T, Chiba N, Muryoi T, Kobayashi H, Fujii H, Sekiguchi Y, Hatakeyama A, Ogura K, Sakuraba H, Asano T, Kanazawa H, Suzuki E, Takasaki S, Asakura K, Sugisaki K, Suzuki Y, Takagi M, Nakayama T, Watanabe H, Miura K, Mori Y; Michinoku Tocilizumab Study Group.

    Mod Rheumatol   ( 2 )   1 - 35   2016.3

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  • Prediction of maintained mucosal healing in patients with Crohn's disease under treatment with infliximab using diffusion-weighted magnetic resonance imaging.

    Hirotake Sakuraba, Yoh Ishiguro, Keisuke Hasui, Hiroto Hiraga, Shinsaku Fukuda, Koichi Shibutani, Yoshihiro Takai

    Digestion   89 ( 1 )   49 - 54   2014.1

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  • Cyclosporine protects from apoptosis-mediated epithelial damage through epithelial STAT3 signaling pathway in DSS-induced colitis

    Hirotake Sakuraba, Yoh Ishiguro, Hiroto Hiraga, Keisuke Hasui, Shinsaku Fukuda

    Inflammatory Bowel Disease   Suppl19 ( 13 )   S103 - S104   2013.12

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  • 大動脈縮窄症術語25年目に発症した人工血管十二指腸ろうの1例

    岡田有史他

    日本消化器病学会雑誌   109   2049 - 2057   2012.5

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  • [Characteristic future of intestinal Behçet's disease and simple ulcer].

    Kazufumi Yamagata, Hirotake Sakuraba, Shinsaku Fukuda, Yoh Ishiguro, Masanori Tanaka

    Nihon rinsho. Japanese journal of clinical medicine   70 Suppl 1   573 - 580   2012.2

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  • [Natural history and disease progression of Crohn's disease].

    Yoh Ishiguro, Keisuke Hasui, Hirotake Sakuraba, Kazufumi Yamagata, Shinsaku Fukuda, Avako Ishiguiro

    Nihon rinsho. Japanese journal of clinical medicine   70 Suppl 1   153 - 158   2012.2

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  • Interferon-a2b induced p21cipI/wafl degradation and cell proliferation in HeLa cells.

    Ken Ota, Tomoh Matsumiya, Hirotake Sakuraba, Tadaatsu Imaizumi, Hidemi Yoshida, Shogo Kawaguchi, Shinsaku Fukuda and Kei Satoh

    Cell Cycle   1   1 - 9   2010.1

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  • Cyclosporine Regulates Intestinal Epithelial Apoptosis via TGF-beta Related Signaling.

    Satoh Y, Ishiguro Y, Sakuraba H, Kawaguchi S, Hiraga H, Fukuda S, Nakane A.

    Am J Physiol Gastrointest Liver Physiol   2009.7

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  • Retinoic acid-inducible gene-I is constitutively expressed and involved in IFN-gamma-stimulated CXCL9-11 production in intestinal epithelial cells.

    Kawaguchi S, Ishiguro Y, Imaizumi T, Mori F, Matsumiya T, Yoshida H, Ota K, Sakuraba H, Yamagata K, Sato Y, Tanji K, Haga T, Wakabayashi K, Fukuda S, Satoh K.

    Immunology Letter   23 ( 123 )   9 - 13   2009.2

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  • Blockade of TGF-beta accelerates mucosal destruction through epithelial cell apoptosis.

    Sakuraba H, Ishiguro Y, Yamagata K, Munakata A, Nakane A.

    Biochem Biophys Res Commun   359 ( 3 )   406 - 412   2007.8

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  • The role of macrophage migration inhibitory factor in lethal Listeria monocytogenes infection in mice.

    3. Sashinami H, Sakuraba H, Ishiguro Y, Munakata A, Nishihira J, Nakane A.

    Micro Pathog   41 ( 2 )   111 - 118   2006.12

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  • Combination chemotherapy with hepatic arterial infusion of 5-fluorouracil and systemic irinotecan in patients with unresectable liver metastases from colorectal cancer.

    Shitara K, Munakata M, Kudo T, Kasai M, Muto O, Okada R, Mitobe S, Ishiguro A, Sakuraba H, Ikami I, Sakata Y

    Gan To Kagaku Ryoho   33 ( 13 )   2033 - 2037   2006.12

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  • Macrophage migration inhibitory factor has a proinflammatory activity via the p38 pathway in glucocorticoid-resistant ulcerative colitis.

    4. Ishiguro Y, Ohkawara T, Sakuraba H, Yamagata K, Hiraga H, Yamaguchi S, Fukuda S, Munakata A, Nakane A,

    Clin Immunol.   120 ( 3 )   335 - 341   2006.11

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  • The presentation of haptenated proteins and activation of T cells in the mesenteric lymphnodes by dendritic cells in the TNBS colitis rat.

    Ishiguro Y, Yamagata K, Sakuraba H, Munakata A,

    Ann N Y Acad Sci.   1029   346 - 347   2004.4

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  • Macrophage migration inhibitory factor and activator protein-1 in ulcerative colitis.

    Ishiguro Y, Yamagata K, Sakuraba H, Nakane A, Munakata A

    Ann N Y Acad Sci.   1029   348 - 349   2004.4

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  • Transforming growth factor-beta regulates susceptibility of epithelial apoptosis in murine model ofcolitis

    5. Sakuraba H, Ishiguro Y, Yamagata K, Tagawa Y, Iwakura Y, Sekikawa K, Munakata A, Nakane A.

    Ann N Y Acad Sci   1029   382 - 384   2004.4

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  • Vaccination with nontoxic mutant toxic shock syndrome toxin 1 protects against Staphylococcus aureus infection.

    Hu DL, Omoe K, Sasaki S, Sashinami H, Sakuraba H, Yokomizo Y, Shinagawa K, Nakane A.

    J Infect Dis.   188   743 - 752   2003.4

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  • Colonic infiltration associated with myelodysplastic syndrome

    9. Ishiguro A, Ishiguro Y, Uno Y, Yamagata K, Sakuraba H, Munakata A.

    Gastrointest Endosc.   54   517 - 519   2001.4

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  • Existence of variant gammadelta T cells in Crohn's disease.

    Ishiguro Y, Kanazawa H, Yamagata K, Sakuraba H, Munakata A.

    Digestion   63   48 - 51   2001.4

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Books

  • 消化器肝臓内科 潰瘍性大腸炎診療の診断から治療をマスターする

    櫻庭裕丈、福田眞作他( Role: Joint author)

    科学評論社  2021.1 

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    Language:Japanese Book type:Scholarly book

  • 炎症性腸疾患の分子標的治療を総括する「接着分子阻害薬―ベドリズマブの特性を生かしたIBD治療」

    1. 櫻庭裕丈,平賀寛人,蓮井桂介,菊池英純,村井康久,川口章吾,樋口直樹,明本由衣,福田眞作( Role: Contributor)

    日本メディカルセンター  2021 

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    Language:Japanese Book type:Scholarly book

  • 下部消化管内視鏡診断アトラス Behcet's病・単純性潰瘍

    櫻庭裕丈、福田眞作( Role: Joint author)

    医学書院  2020.10 

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    Language:Japanese Book type:Scholarly book

  • 消化器医のための重要論文240篇 炎症性腸疾患編

    櫻庭裕丈、福田眞作( Role: Joint author)

    株式会社シービーアール  2020.1 

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    Language:Japanese Book type:Scholarly book

  • 消化器疾患 最新の治療 消化管全般にわたるもの「膠原病の消化器病変」

    櫻庭裕丈、福田眞作( Role: Joint author)

    南江堂  2020.1 

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  • 腸管ベーチェット病のすべてがわかる

    田中正則、明本由衣、櫻庭裕丈( Role: Joint author)

    先端医学社  2019 

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  • 消化器疾患 最新の治療

    櫻庭裕丈、福田眞作( Role: Joint author)

    南江堂  2019 

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  • 高齢者の消化器疾患

    山形和史、櫻庭裕丈、佐竹美和、福田眞作 他( Role: Joint author)

    新興医学出版社  2016.11 

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  • 成人病と生活習慣病 ここまで来た炎症性腸疾患の新展開

    平賀寛人、山形和史、櫻庭裕丈、佐竹美和、福田眞作( Role: Joint author)

    東京医学社  2014.3 

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    Language:Japanese

  • 日本医師会雑誌 第141巻・特別号(2) 消化器疾患診療のすべて

    「櫻庭裕丈」「石黒 陽」「福田眞作」( Role: Joint author)

    日本医師会  2012.10 

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  • 日本臨床 増刊号 炎症性腸疾患

    山形和史 他( Role: Joint author)

    日本臨床社  2012.2 

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  • 日本臨床 増刊号 炎症性腸疾患

    石黒 陽 他( Role: Joint author)

    日本臨床社  2012.2 

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  • 症状からアプローチするプライマリケア

    櫻庭裕丈、蓮井桂介、福田眞作( Role: Joint author ,  下痢)

    日本医師会 医歯薬出版株式会社  2011.12 

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    Language:Japanese Book type:Scholarly book  Code for field of experts (e-Rad):Life Science / Gastroenterology

  • IBD炎症性腸疾患を究める

    石黒陽、櫻庭裕丈、福田眞作( Role: Joint author ,  炎症性腸疾患に伴う合併症)

    メジカルビュー  2011.11 

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Awards

  • The Best Presenter Award in International Session

    2019.11

  • 第21回弘前大学医学部国際化教育奨励賞

    2018.01

  • 弘前大学医学部学術特別賞

    2018.01

  • 第12回弘前大学医学部学術奨励賞

    2008.02

Social Activities

  • 日本消化器病学会東北支部 第25回教育講演会

    2023.10.15

  • 炎症性腸疾患 市民公開講座

    2012.06

  • 平成20年度難病患者医療相談

    2008.12