Papers - SAKURABA Hirotake
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First-line biologics as a treatment for ulcerative colitis: a multicenter randomized control study
Matsumoto T, Hisamatsu T, Esaki M, et al
J Gastroenterol. 2025 Apr;60(4):430-441. 2025.4
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Peroral endoscopic myotomy in spastic esophageal disorders: Clinical outcomes and optimal approaches.
Tetsuya TATSUTA et al
Dig Endosc. 2025 Mar 17. ( 2025 Mar 17. ) 2025.4
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Peroral endoscopic myotomy in spastic esophageal disorders: Clinical outcomes and optimal approaches.
Tatsuta T, Inoue H, Shimamura Y, Iwasaki M, Ushikubo K, Yamamoto K, Nishikawa Y, Tanaka H, Tanaka I, Abiko S, Tanabe M, Sumi K, Onimaru M, Gantuya B, Sakuraba H, Fukuda S
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2025.3
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Guidelines for endoscopic diagnosis and treatment of inflammatory bowel diseases.
Matsumoto T, Hisamatsu T, Esaki M, Omori T, Sakuraba H, Shinzaki S, Sugimoto K, Takenaka K, Naganuma M, Bamba S, Hisabe T, Hiraoka S, Fujiya M, Matsuura M, Yanai S, Watanabe K, Ogata H, Andoh A, Nakase H, Ohtsuka K, Hirai F, Fujishiro M, Igarashi Y, Tanaka S
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2025.3
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Involvement of Mediterranean fever gene mutations in colchicine-responsive enterocolitis: a retrospective cohort study.
Nakase H, Wagatsuma K, Kobayashi T, Matsumoto T, Esaki M, Watanabe K, Kunisaki R, Takeda T, Arai K, Ibuka T, Ishikawa D, Matsuno Y, Sakuraba H, Ueno N, Yokoyama K, Saruta M, Hokari R, Yokoyama J, Tamano S, Nojima M, Hisamatsu T, MEFV-IBDU Group
EBioMedicine 110 105454 2024.12
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Anxiety and behavioral changes in Japanese patients with inflammatory bowel disease due to COVID-19 pandemic: a national survey.
Nakase H, Wagatsuma K, Nojima M, Matsumoto T, Matsuura M, Iijima H, Matsuoka K, Ohmiya N, Ishihara S, Hirai F, Takeuchi K, Tamura S, Kinjo F, Ueno N, Naganuma M, Watanabe K, Moroi R, Nishimata N, Motoya S, Kurahara K, Takahashi S, Maemoto A, Sakuraba H, Saruta M, Tominaga K, Hisabe T, Tanaka H, Terai S, Hiraoka S, Takedomi H, Narimatsu K, Endo K, Nakamura M, Hisamatsu T
Journal of gastroenterology 58 ( 3 ) 205 - 216 2023.3
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A case of isolated pancreatic sarcoidosis presenting with acute pancreatitis necessitating a differential diagnosis from pancreatic cancer.
Nao Ishidoya, Satoshi Sato, Masakazu Tobinai, Kaede Miyashiro, Kenta Yoshida, Chikara Iino, Hirotake Sakuraba
Clinical journal of gastroenterology 2026.1
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Medical treatment of intestinal Behçet's disease:molecular targeted agents
SAKURABA Hirotake, HIRAGA Hiroto, HASUI Keisuke
Nippon Shokakibyo Gakkai Zasshi 122 ( 11 ) 757 - 763 2025.11
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Targeting Overexpressed IDO in Stromal Cells as a Potential Therapeutic Strategy in Multiple Myeloma.
Ebina T, et al
Cancer Sci. 2025 Nov 26. ( 2025 Nov 26. ) 2025.9
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Who Needs Endoscopic Removal of Food Residue From the Esophagus Before Peroral Endoscopic Myotomy for Esophageal Achalasia and Esophagogastric Junction Outflow Obstruction?
Kaizuka M, et al
DEN Open. 2025 Sep 3;6(1):e701 ( 2025 Sep 3;6(1):e701 ) 2025 Sep 3;6(1):e701 - 2025 Sep 3;6(1):e701 2025.9
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Influence of transarterial chemoembolization on serum opsonic activity in hepatocellular carcinoma measured by chemiluminescence.
Satoshi SATO, et al
J Clin Biochem Nutr. 2025 Sep 1;77(2):195 ( 2025 Sep 1;77(2):195 ) 2025 Sep 1;77(2):195 - 2025 Sep 1;77(2):195 2025.9
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Post Hoc Analysis of Anxiety and Behavioral Changes in Japanese Patients With Inflammatory Bowel Disease due to the COVID-19 Pandemic: Relationship Between Municipal Population at the Place of Residence and Anxiety.
Wagatsuma K , et al
JGH Open. 2025.7
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Successful treatment with hyperbaric oxygen therapy for ulcerative esophageal stricture after chemoradiotherapy: A case report.
Tateda T, Kikuchi H, Furusawa K, Matsuoka Y, Asari T, Sawada Y, Nakagawa S, Tetsuya T, Chinda D, Sakuraba H
DEN open 5 ( 1 ) e70072 2025.4
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First-line biologics as a treatment for ulcerative colitis: a multicenter randomized control study.
Naganuma M, et al
J Gastroenterol. 2025 Apr;60(4):430-4 ( 2025 Apr;60(4):430-4 ) 2025 Apr;60(4):430-4 - 2025 Apr;60(4):430-4 2025.4
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Effect of Oral Microbiota Composition on Metabolic Dysfunction-Associated Steatotic Liver Disease in the General Population.
Satoshi SATO, et al
J Clin Med. 2025 Mar 16;14(6):20 ( 2025 Mar 16;14(6):20 ) 2025 Mar 16;14(6):20 - 2025 Mar 16;14(6):20 2025.4
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Solitary Peutz-Jeghers polyp harboring a focus of high-grade dysplasia in the colon: a case report and literature review.
Maeda T, Yoshizawa T, Oyama T, Nakagawa S, Murai Y, Machida R, Ishidoya N, Sakamoto J, Iwamura H, Sakuraba H
Clinical journal of gastroenterology 18 ( 1 ) 89 - 94 2025.2
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Successful treatment with hyperbaric oxygen therapy for ulcerative esophageal stricture after chemoradiotherapy: A case report.
DEN Open 2025 Jan 29;5(1):e70 ( 2025 Jan 29;5(1):e70 ) 2025.1
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A 4-year cohort study of the effects of PNPLA3 rs738409 genotypes on liver fat and fibrosis and gut microbiota in a non-fatty liver population
Sato Satoshi, Iino Chikara, Sasada Takafumi, Furusawa Keisuke, Yoshida Kenta, Sawada Kaori, Mikami Tatsuya, Fukuda Shinsaku, Nakaji Shigeyuki, Sakuraba Hirotake
Environmental Health and Preventive Medicine 30 ( 0 ) 17 - 17 2025
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Heat-killed <i>Lactococcus lactis</i> subsp. <i>lactis</i> L8 ameliorates dextran sulfate sodium-induced colitis in mice
Kawaguchi Shogo, Chinda Daisuke, Ota Shinji, Tonouchi Akio, Maeda Hayato, Miura Kazuhide, Soma Go, Hiraga Hiroto, Ueno Kayo, Niioka Takenori, Tachizaki Mayuki, Seya Kazuhiko, Imaizumi Tadaatsu, Fukuda Shinsaku, Sakuraba Hirotake
Journal of Clinical Biochemistry and Nutrition advpub ( 0 ) 2025
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Gut microbiota involvement in the effect of water-soluble dietary fiber on fatty liver and fibrosis
SATO Satoshi, IINO Chikara, CHINDA Daisuke, SASADA Takafumi, SOMA Go, TATEDA Tetsuyuki, FURUSAWA Keisuke, YOSHIDA Kenta, SAWADA Kaori, MIKAMI Tatsuya, NAKAJI Shigeyuki, SAKURABA Hirotake, FUKUDA Shinsaku
Bioscience of Microbiota, Food and Health 44 ( 1 ) 49 - 57 2025
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An epidemiological study on the factors including genetic polymorphism influencing ALT >30 U/L and liver fibrosis progression in metabolic dysfunction-associated steatotic liver disease among the general population.
Sato S, Iino C, Sasada T, Soma G, Furusawa K, Yoshida K, Sawada K, Mikami T, Fukuda S, Nakaji S, Sakuraba H
JGH open : an open access journal of gastroenterology and hepatology 8 ( 12 ) e70043 2024.12
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特集 大腸の炎症を内視鏡で診る [IBD以外の大腸の炎症性疾患の内視鏡診療] 薬剤起因性腸炎
菊池 英純, 櫻庭 裕丈, 明本 由衣, 野宮 洋樹, 松岡 祐介, 相馬 郷, 太田 真二, 蓮井 桂介, 平賀 寛人
消化器内視鏡 36 ( 11 ) 1545 - 1548 2024.11
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特集 炎症性腸疾患update [Chapter 1] IBDの病態・診断・病勢評価のupdate IBDとはどのような病気か
櫻庭 裕丈, 平賀 寛人, 菊池 英純, 蓮井 桂介, 太田 真二
内科 134 ( 5 ) 988 - 991 2024.11
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増大号 炎症性腸疾患2024 主題 炎症性腸疾患の長期経過 潰瘍性大腸炎の長期予後
蓮井 桂介, 平賀 寛人, 太田 真二, 浅利 享, 澤田 洋平, 立田 哲也, 川口 章吾, 菊池 英純, 珍田 大輔, 明本 由衣, 坂本 義之, 袴田 健一, 福田 眞作, 櫻庭 裕丈
胃と腸 59 ( 10 ) 1521 - 1530 2024.10
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Epidemiological Study on the Interaction between the PNPLA3 (rs738409) and Gut Microbiota in Metabolic Dysfunction-Associated Steatotic Liver Disease.
Sato S, Iino C, Sasada T, Soma G, Furusawa K, Yoshida K, Sawada K, Mikami T, Nakaji S, Sakuraba H, Fukuda S
Genes 15 ( 9 ) 2024.9
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The Impact of Japanese Dietary Patterns on Metabolic Dysfunction-Associated Steatotic Liver Disease and Liver Fibrosis.
Sasada T, Iino C, Sato S, Tateda T, Igarashi G, Yoshida K, Sawada K, Mikami T, Nakaji S, Sakuraba H, Fukuda S
Nutrients 16 ( 17 ) 2024.8
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A CASE OF ACUTE MYELOID LEUKEMIA WITH PLATELET TRANSFUSION IN A REFRACTORY STATE DUE TO ANTI-HPA-5a ANTIBODY BEFORE INITIAL REMISSION INDUCTION THERAPY
Yamaguchi Kohei, Mayama Ko, Ishiguro Yoh, Kamata Kosuke, Sakuraba Hirotake, Kubo Kohmei, Tamai Yoshiko
Japanese Journal of Transfusion and Cell Therapy 70 ( 4 ) 509 - 514 2024.8
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Colorectal Post-polypectomy Bleeding in Outpatient versus Inpatient Treatment: Propensity Score Matching Analysis
Maeda Takato, Sakuraba Hirotake, Oyama Takao, Nakagawa Satoru, Ota Shinji, Murai Yasuhisa, Machida Ryuma, Ishidoya Nao, Kikuchi Hidezumi, Chinda Daisuke, Sakamoto Juichi, Iwamura Hideki
Journal of the Anus, Rectum and Colon 8 ( 3 ) 204 - 211 2024.7
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Factors Predicting Effectiveness of Eradication Therapy for Helicobacter pylori-Associated Dyspepsia Symptoms.
Yasuda K, Chinda D, Shimoyama T, Arai T, Akitaya K, Fujiwara S, Nomiya H, Sasaki Y, Komai K, Sawada Y, Saito Y, Chiba H, Sakuraba H, Fukuda S, The Ringo Study Group
Life (Basel, Switzerland) 14 ( 8 ) 2024.7
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Resiquimod Induces C-C Motif Chemokine Ligand 2 Via Nuclear Factor-Kappa B in SH-SY5Y Human Neuroblastoma Cells.
Kaizuka M, Kawaguchi S, Tatsuta T, Tachizaki M, Kobori Y, Tanaka Y, Seya K, Matsumiya T, Imaizumi T, Sakuraba H
Neuromolecular medicine 26 ( 1 ) 16 2024.4
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The new 222-nm far ultraviolet-C lowers bacterial contamination to endoscopists during esophagogastroduodenoscopy.
Fukutoku Y, Kikuchi H, Hoshi K, Narita K, Asari T, Miyazawa K, Sawada Y, Hayamizu S, Tatsuta T, Oota S, Hasui K, Hiraga H, Chinda D, Mikami T, Subsomwong P, Asano K, Yamane K, Ogawa Y, Sasaki M, Koi T, Ohashi H, Nakane A, Sakuraba H
DEN open 4 ( 1 ) e292 2024.4
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Impact of the COVID-19 pandemic on the performance of endoscopy in the Tohoku region of Japan.
Iijima K, Matsuhashi T, Shimodaira Y, Mikami T, Yoshimura T, Yanai S, Kudara N, Tsuji T, Matsushita HO, Watanabe H, Koike T, Kato K, Abe Y, Shirahata N, Hikichi T, Katakura K, Kono K, Sakuraba H, Ueno Y, Ohira H, Masamune A, Matsumoto T, Fukuda S, Japan Gastroenterological Endoscopy Society‐Tohoku
DEN open 4 ( 1 ) e249 2024.4
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A Cohort Study of the Influence of the 12-Component Modified Japanese Diet Index on Oral and Gut Microbiota in the Japanese General Population.
Satoshi Sato, Daisuke Chinda, Chikara Iino, Kaori Sawada, Tatsuya Mikami, Shigeyuki Nakaji, Hirotake Sakuraba, Shinsaku Fukuda
Nutrients 16 ( 4 ) 2024.2
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A CASE OF GASTRIC ADENOCARCINOMA WITH ENTEROBLASTIC DIFFERENTIATION RESECTED BY ESD
SATO Satoshi, CHINDA Daisuke, TATSUTA Tetsuya, HIGUCHI Hiroyuki, KIKUCHI Hidezumi, SAKURABA Hirotake, MIKAMI Tatsuya, YOSHIZAWA Tadashi, KIJIMA Hiroshi, FUKUDA Shinsaku
GASTROENTEROLOGICAL ENDOSCOPY 66 ( 3 ) 273 - 278 2024
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Toll-Like Receptor 7-Expressed Macrophages Are Involved in the Pathogenesis of Esophageal Achalasia and Esophagogastric Junction Outflow Obstruction.
Kaizuka M, Tatsuta T, Kawaguchi S, Yoshizawa T, Yoshida S, Tateda T, Sawada Y, Ota S, Hayamizu S, Hasui K, Kikuchi H, Hiraga H, Chinda D, Muroya T, Hakamada K, Kijima H, Mikami T, Fukuda S, Sakuraba H
Digestion 105 ( 6 ) 436 - 447 2024
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A Logistic Regression Model for Predicting the Risk of Subsequent Surgery among Patients with Newly Diagnosed Crohn's Disease Using a Brute Force Method.
Ogasawara K, Hiraga H, Sasaki Y, Hiraga N, Higuchi N, Hasui K, Ota S, Maeda T, Murai Y, Tatsuta T, Kikuchi H, Chinda D, Mikami T, Matsuzaka M, Sakuraba H, Fukuda S
Diagnostics (Basel, Switzerland) 13 ( 23 ) 2023.12
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QUASAR Study Group. Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis: QUASAR Phase 2b Induction Study.
Peyrin-Biroulet L, et al.
Gastroenterology. 2023 Dec;165(6):1443-1457. 2023.12
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Influence of CYP3A5 and ABCB1 polymorphisms on the pharmacokinetics of vincristine in adult patients receiving CHOP therapy.
Nakagawa J, Takahata T, Chen Y, Saito K, Kamata K, Tachita T, Yamashita S, Saito K, Ueno K, Sato A, Sakuraba H, Niioka T
Cancer chemotherapy and pharmacology 92 ( 5 ) 391 - 398 2023.11
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Trajectory analyses to identify persistently low responders to COVID-19 vaccination in patients with inflammatory bowel disease: a prospective multicentre controlled study, J-COMBAT.
Watanabe K, Nojima M, Nakase H, Sato T, Matsuura M, Aoyama N, Kobayashi T, Sakuraba H, Nishishita M, Yokoyama K, Esaki M, Hirai F, Nagahori M, Nanjo S, Omori T, Tanida S, Yokoyama Y, Moriya K, Maemoto A, Handa O, Ohmiya N, Tsuchiya K, Shinzaki S, Kato S, Uraoka T, Tanaka H, Takatsu N, Nishida A, Umeno J, Nakamura M, Mishima Y, Fujiya M, Tsuchida K, Hiraoka S, Okabe M, Toyonaga T, Matsuoka K, Andoh A, Hirota Y, Hisamatsu T, J-COMBAT study group
Journal of gastroenterology 58 ( 10 ) 1015 - 1029 2023.10
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Effect of Liver Fibrosis on Oral and Gut Microbiota in the Japanese General Population Determined by Evaluating the FibroScan-Aspartate Aminotransferase Score.
Sato S, Iino C, Chinda D, Sasada T, Tateda T, Kaizuka M, Nomiya H, Igarashi G, Sawada K, Mikami T, Nakaji S, Sakuraba H, Fukuda S
International journal of molecular sciences 24 ( 17 ) 2023.8
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Assessment of the Physical Invasiveness of Peroral Endoscopic Myotomy during the Perioperative Period Based on Changes in Energy Metabolism.
Chinda D, Shimoyama T, Fujiwara S, Kaizuka M, Yasuda K, Akitaya K, Arai T, Sawada Y, Hayamizu S, Tatsuta T, Kikuchi H, Yanagimachi M, Mikami T, Sakuraba H, Fukuda S
Metabolites 13 ( 9 ) 2023.8
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Endoscopic drainage with a metallic stent for obstructive jaundice caused by bile duct metastasis of breast cancer: A case report.
Yoshida K, Yokoyama M, Hirao Y, Sato Y, Saito T, Soma Y, Mizukami H, Fukuda S, Sakuraba H
Clinical case reports 11 ( 6 ) e7543 2023.6
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Vitamin A Promotes the Fusion of Autophagolysosomes and Prevents Excessive Inflammasome Activation in Dextran Sulfate Sodium-Induced Colitis.
Hiraga H, Chinda D, Maeda T, Murai Y, Ogasawara K, Muramoto R, Ota S, Hasui K, Sakuraba H, Ishiguro Y, Yoshida S, Asano K, Nakane A, Fukuda S
International journal of molecular sciences 24 ( 10 ) 2023.5
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A trial deep learning-based model for four-class histologic classification of colonic tumor from narrow band imaging.
Shimizu T, Sasaki Y, Ito K, Matsuzaka M, Sakuraba H, Fukuda S
Scientific reports 13 ( 1 ) 7510 2023.5
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Bacterial exposure risk to the endoscopist's face while performing endoscopy.
Hoshi K, Kikuchi H, Narita K, Fukutoku Y, Asari T, Miyazawa K, Murai Y, Sawada Y, Tatsuta T, Hasui K, Hiraga H, Chinda D, Mikami T, Subsomwong P, Asano K, Nakane A, Fukuda S, Sakuraba H
DEN open 3 ( 1 ) e209 2023.4
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Polygonum tinctorium leaf extract ameliorates high-fat diet-induced intestinal epithelial damage in mice.
Kawaguchi S, Sakuraba H, Kikuchi H, Matsuki K, Hayashi Y, Ding J, Tanaka Y, Seya K, Matsumiya T, Hiraga H, Fukuda S, Sasaki K, Imaizumi T
Experimental and therapeutic medicine 25 ( 3 ) 112 2023.3
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Evaluation of Crohn's Disease Small-Bowel Mucosal Healing Using Capsule Endoscopy and Usefulness of Leucine-Rich α2-Glycoprotein.
Hiraga H, Chinda D, Hasui K, Murai Y, Maeda T, Higuchi N, Ogasawara K, Kudo S, Sawada Y, Tatsuta T, Kikuchi H, Ebina M, Hiraga N, Mikami T, Sakuraba H, Fukuda S
Diagnostics (Basel, Switzerland) 13 ( 4 ) 2023.2
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Association between reactive oxygen species production in neutrophils and liver fibrosis in the general population
Sato Satoshi, Nakaji Shigeyuki, Sawada Kaori, Akimoto Naoki, Tateda Tetsuyuki, Kaizuka Masatoshi, Sasada Takafumi, Nomiya Hiroki, Igarashi Go, Iino Chikara, Chinda Daisuke, Mikami Tatsuya, Sakuraba Hirotake, Fukuda Shinsaku
Journal of Clinical Biochemistry and Nutrition 73 ( 3 ) 214 - 220 2023
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Tryptanthrin attenuates TLR3-mediated STAT1 activation in THP-1 cells.
Numao N, Kawaguchi S, Ding J, Karasawa T, Seya K, Matsumiya T, Kikuchi H, Sakuraba H, Fukuda S, Imaizumi T
Immunologic research 70 ( 5 ) 688 - 697 2022.10
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A Cohort Study of the Effects of Daily-Diet Water-Soluble Dietary Fiber on Butyric Acid-Producing Gut Microbiota in Middle-Aged and Older Adults in a Rural Region.
Satoshi Sato, Daisuke Chinda, Tadashi Shimoyama, Chikara Iino, Sae Kudo, Kaori Sawada, Tatsuya Mikami, Shigeyuki Nakaji, Hirotake Sakuraba, Shinsaku Fukuda
Microorganisms 10 ( 9 ) 2022.9
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Clinical Features of Fecal Immunochemical Test-Negative Colorectal Lesions based on Colorectal Cancer Screening among Asymptomatic Participants in Their 50s.
Suto S, Matsuzaka M, Sawaya M, Sakuraba H, Mikami T, Matsuda T, Fujii T, Saito Y, Hotta K, Ikematsu H, Hanabata N, Saito H, Yoshida S, Fukuda S
Asian Pacific journal of cancer prevention : APJCP 23 ( 7 ) 2325 - 2332 2022.7
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Polygonum tinctorium leaves suppress sodium dextran sulfate-induced colitis through interleukin-10-related pathway.
Asari T, Kikuchi H, Kawaguchi S, Sakuraba H, Yoshida S, Akemoto Y, Maeda T, Shinji O, Murai Y, Higuchi N, Hoshi K, Fukutoku Y, Hiraga H, Sasaki K, Fukuda S
Biochemistry and biophysics reports 30 101272 2022.7
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Tacrolimus Up-regulates Expression of TGFβ Receptor Type II via ERK, Providing Protection Against Intestinal Epithelial Injury.
Satake M, Sakuraba H, Hiraga H, Yoshida S, Akemoto Y, Ota S, Murai Y, Hasui K, Kawaguchi S, Kikuchi H, Fukuda S
In vivo (Athens, Greece) 36 ( 4 ) 1684 - 1693 2022.7
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Reduced Equol Production and Gut Microbiota Features in Men With Lean Nonalcoholic Fatty Liver Disease.
Iino C, Endo T, Iino K, Tateda T, Sato S, Igarashi G, Mikami K, Sakuraba H, Yokoyama Y, Nakaji S, Fukuda S
American journal of men's health 16 ( 4 ) 15579883221115598 2022.7
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増刊号 図説「胃と腸」画像診断用語集2022 分類・定義 腸 潰瘍性大腸炎の内視鏡的重症度分類
櫻庭 裕丈, 福田 眞作
胃と腸 57 ( 5 ) 708 - 709 2022.5
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Influence of Esophageal Endoscopic Submucosal Dissection on the Changes of Energy Metabolism during the Perioperative Period.
Kudo S, Chinda D, Shimoyama T, Yasuda K, Akitaya K, Arai T, Miyazawa K, Hayamizu S, Yanagimachi M, Tsukamoto T, Kaizuka M, Sawada Y, Tatsuta T, Hasui K, Kikuchi H, Hiraga H, Sakuraba H, Mikami T, Fukuda S
Cancers 14 ( 8 ) 2022.4
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Endoscopic and histopathologic features of Anti-PD-1-related collagenous colitis.
Kikuchi H, Sakuraba H, Akemoto Y, Hosoi K, Murai Y, Hoshi K, Fukutoku Y, Asari T, Sawada Y, Hasui K, Tatsuta T, Hiraga H, Chinda D, Mikami T, Fukuda S
DEN open 2 ( 1 ) e92 2022.4
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Impact of polymorphisms of pharmacokinetics-related genes and the inflammatory response on the metabolism of voriconazole.
Aiuchi N, Nakagawa J, Sakuraba H, Takahata T, Kamata K, Saito N, Ueno K, Ishiyama M, Yamagata K, Kayaba H, Niioka T
Pharmacology research & perspectives 10 ( 2 ) e00935 2022.4
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Spatial distribution of live gut microbiota and bile acid metabolism in various parts of human large intestine
Chinda D, Takada T, Mikami T, Shimizu K, Oana K, Arai T, Akitaya K, Sakuraba H, Katto M, Nagara Y, Makino H, Fujii D, Oishi K, Fukuda S
Sci Rep 2022.3
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Impact of polymorphisms of pharmacokinetics-related genes and the inflammatory response on the metabolism of voriconazole
Aiuchi N, Nakagawa J, Sakuraba H, Takahata T, Kamata K, Saito N, Ueno K, Ishiyama M, Yamagata K, Kayaba H, Niioka T
Pharmacol Res Perspect 2022.1
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Automated evaluation of colon capsule endoscopic severity of ulcerative colitis using ResNet50.
Higuchi N, Hiraga H, Sasaki Y, Hiraga N, Igarashi S, Hasui K, Ogasawara K, Maeda T, Murai Y, Tatsuta T, Kikuchi H, Chinda D, Mikami T, Matsuzaka M, Sakuraba H, Fukuda S
PloS one 17 ( 6 ) e0269728 2022
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Evaluation of metabolic dysfunction-associated fatty liver disease using FibroScan, diet, and microbiota: A large cross-sectional study.
Tateda T, Iino C, Sasada T, Sato S, Igarashi G, Kawaguchi S, Mikami K, Endo T, Sawada K, Mikami T, Fukuda S, Nakaji S, Sakuraba H
PloS one 17 ( 11 ) e0277930 2022
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Association of serum creatinine-to-cystatin C ratio with skeletal muscle mass and strength in nonalcoholic fatty liver disease in the Iwaki Health Promotion Project
2. Mikami K, Endo T, Sawada N, Igarashi G, Kimura M, Hasegawa T, Iino C, Sawada K, Ando M, Nakaji S, Matsuzaka M, Sakuraba H, Fukuda S
J Clin Biochem Nutr 2021.12
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Active and passive smoking and risk of ulcerative colitis: A case-control study in Japan
1. Nishikawa A, Tanaka K, Miyake Y, Nagata C, Furukawa S, Andoh A, Yokoyama T, Yoshimura N, Mori K, Ninomiya T, Yamamoto Y, Takeshita E, Ikeda Y, Saito M, Ohashi K, Imaeda H, Kakimoto K, Higuchi K, Nunoi H, Mizukami Y, Suzuki S, Hiraoka S, Okada H, Kawasaki K, Higashiyama M, Hokari R, Miura H, Miyake T, Kumagi T, Kato H, Hato N, Sayama K, Hiasa Y and Japan Ulcerative Colitis Study Group (Sakuraba H)
J Gastroenterol Hepatol 2021.12
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Macrophages Express Melanoma Differentiation-Associated Gene 5 in Nonalcoholic Steatohepatitis
Kawaguchi S, Sakuraba H, Horiuchi M, Ding J, Matsumiya T, Seya K, Iino C, Endo T, Kikuchi H, Yoshida S, Hiraga H, Fukuda S, Imaizumi T
Inflammation 2021.12
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Leptomeningeal andintraventricular myelomatosis manifesting an aggressive form of communicating hydrocephalus
Miki Y, Kamata K, Akemoto Y, Tsushima F, Sakuraba H, Yamagata K, Fukuda S, Wakabayashi K
Neuropathology 2021.1
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Genetic background of mesalamine-induced fever and diarrhea in Japanese patients with inflammatory bowel disease
Suzuki K, Kakuta Y, Naito T, Takagawa T, Hanai H, Araki H, Sasaki Y, Sakuraba H, Sasaki M, Hisamatsu T, Motoya S, Matsumoto T, Onodera M, Ishiguro Y, Nakase H, Andoh A, Hiraoka S, Shinozaki M, Fujii T, Katsurada T, Kobayashi T, Fujiya M, Otsuka T, Oshima N, Suzuki Y, Sato Y, Hokari R, Noguchi M, Ohta Y, Matsuura M, Kawai Y, Tokunaga K, Nagasaki M, Kudo H, Minegishi N, Okamoto D, Shimoyama Y, Moroi R, Kuroha M, Shiga H, Li D, P.B McGovern D, Kinouchi Y, Masamune A
Inflamm Bowel Dis 2021.1
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Long-term efficacy and tolerability of dose-adjusted thiopurine treatment in maintaining remission in inflammatory bowel disease patients with NUDT15 heterozygosity
Maeda T, Sakuraba H, Hiraga H, Yoshida S, Kakuta Y, Kikuchi H, Kawaguchi S, Hasui K, Tatsuta T, Chinda D, Mikami T, Fukuda S
Intest Res 2021.1
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Tryptanthrin suppresses double-stranded RNA-induced CXCL10 expression via inhibiting the phosphorylation of STAT1 in human umbilical vein endothelial cells
Kawaguchi S, Sakuraba H, Kikuchi H, Numao N, Asari T, Hiraga H, Ding J, Matsumiya T, Seya K, Fukuda S, Imaizumi T
Mol Immunol 2021.1
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Dietary intake of vegetables, fruit, and antioxidants and risk of ulcerative colitis: a case-control study in Japan
Miyake Y, Tanaka K, Nagata C, Furukawa S, Andoh A, Yokoyama T, Yoshimura N, Mori K, Ninomiya T, YamamotoY, Takeshita E, Ikeda Y, Saito M, Ohashi K, Imaeda H, Kakimoto K, Higuchi K, Nunoi H, Mizukami Y, Suzuki S, Hiraoka S, Okada H, Kawasaki K, Higashiyama M, Hokari R, Miura H, Miyake T, Kumagi T, Kato H, Hato N, Sayama K, Hiasa Y, and Japan Ulcerative Colitis Study Group (Sakuraba H).
Nutrition 2021
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Cyclosporine protects from intestinal epithelial injury by modulating butyrate uptake via upregulation of membrane monocarboxylate transporter 1 levels
Ota S, Sakuraba H
Biochem Biophys Rep 2020.12
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5. Anatomical classification of upper gastrointestinal organs under various image capture conditions using AlexNet
Igarashi S, Sasaki Y, Mikami T, Sakuraba H, Fukuda S
Comput Biol Med 2020.10
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Anatomical classification of upper gastrointestinal organs under various image capture conditions using AlexNet.
Igarashi S, Sasaki Y, Mikami T, Sakuraba H, Fukuda S
Computers in biology and medicine 124 103950 2020.9
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A nationwide, multi-center, retrospective study of symptomatic small bowel stricture in patients with Crohn's disease.
Shigeki Bamba, Ryosuke Sakemi, Toshimitsu Fujii, Teruyuki Takeda, Shin Fujioka, Kento Takenaka, Hiroki Kitamoto, Shotaro Umezawa, Hirotake Sakuraba, Toshihiro Inokuchi, Norimasa Fukata, Shinta Mizuno, Masaki Yamashita, Shinichiro Shinzaki, Hiroki Tanaka, Hidetoshi Takedatsu, Ryo Ozaki, Kei Moriya, Manabu Ishii, Tetsu Kinjo, Keiji Ozeki, Makoto Ooi, Ryohei Hayashi, Kazuki Kakimoto, Yuichi Shimodate, Kazuya Kitamura, Akihiro Yamada, Akira Sonoda, Yu Nishida, Kyouko Yoshioka, Shinya Ashizuka, Fumiaki Takahashi, Toshio Shimokawa, Taku Kobayashi, Akira Andoh, Toshifumi Hibi
Journal of gastroenterology 2020.1
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Case report of lanthanum deposition in the esophagus.
Tetsuya Tatsuta, Tatsuya Mikami, Daisuke Chinda, Kazuki Akitaya, Shohei Igarashi, Keisuke Hasui, Hidezumi Kikuchi, Hiroto Hiraga, Manabu Sawaya, Hirotake Sakuraba, Tadashi Shimoyama, Tosihiro Haga, Hiroshi Kijima, Shinsaku Fukuda
Clinical journal of gastroenterology 2019.12
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Diagnostic approach for patients with unidentified fever according to the classical criteria of fever of unknown origin in the field of autoimmune disorders.
Rina Watanabe, Hirotake Sakuraba, Hiroto Hiraga, Dai Kishida, Shinji Ota, Keisuke Hasui, Hidezumi Kikuchi, Yui Akemoto, Nahoko Tanaka, Takato Maeda, Yasuhisa Murai, Shukuko Yoshida, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Yoh Ishiguro, Shinsaku Fukuda
Immunological medicine 42 ( 4 ) 176 - 184 2019.12
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Melanoma Differentiation-Associated Gene 5 Positively Modulates TNF-α-Induced CXCL10 Expression in Cultured HuH-7 and HLE Cells.
Shogo Kawaguchi, Hirotake Sakuraba, Toshihiro Haga, Tomoh Matsumiya, Kazuhiko Seya, Tetsu Endo, Naoya Sawada, Chikara Iino, Hidezumi Kikuchi, Hiroto Hiraga, Shinsaku Fukuda, Tadaatsu Imaizumi
Inflammation 42 ( 6 ) 2095 - 2104 2019.12
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Usefulness of serum opsonic activity measured by chemiluminescence method to assess the invasiveness of colorectal endoscopic mucosal dissection.
Daisuke Chinda, Tadashi Shimoyama, Tetsu Arai, Kaori Sawada, Kazuki Akitaya, Sae Kudo, Kohei Yasuda, Kuniaki Miyazawa, Naoki Akimoto, Satoshi Sato, Shiro Hayamizu, Tetsuya Tatsuta, Hidezumi Kikuchi, Hiroto Hiraga, Manabu Sawaya, Hirotake Sakuraba, Tatsuya Mikami, Shigeyuki Nakaji, Shinsaku Fukuda
Free radical research 1 - 8 2019.10
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Withdrawal of thiopurines in Crohn's disease treated with scheduled adalimumab maintenance: a prospective randomised clinical trial (DIAMOND2).
Tadakazu Hisamatsu, Shingo Kato, Reiko Kunisaki, Minoru Matsuura, Masakazu Nagahori, Satoshi Motoya, Motohiro Esaki, Norimasa Fukata, Satoko Inoue, Takeshi Sugaya, Hirotake Sakuraba, Fumihito Hirai, Kenji Watanabe, Takanori Kanai, Makoto Naganuma, Hiroshi Nakase, Yasuo Suzuki, Mamoru Watanabe, Toshifumi Hibi, Masanori Nojima, Takayuki Matsumoto,
Journal of gastroenterology 54 ( 10 ) 860 - 870 2019.10
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Long-term maintenance of the mucosal healing induced by azacitidine therapy in a patient with intestinal Behçet's-like disease accompanied with myelodysplastic syndrome involving trisomy 8.
Nahoko Tanaka, Hirotake Sakuraba, Hiroto Hiraga, Ko Mayama, Hidezumi Kikuchi, Dai Kishida, Yui Akemoto, Keisuke Hasui, Shinji Ota, Rina Watanabe, Yasuhisa Murai, Takato Maeda, Kosuke Kamata, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Kazufumi Yamagata, Yoh Ishiguro, Masanori Tanaka, Shinsaku Fukuda
Immunological medicine 42 ( 3 ) 135 - 141 2019.9
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A case of celiac disease with type I enteropathy-associated T-cell lymphoma in a Japanese male patient.
Hiroto Hiraga, Hirotake Sakuraba, Nahoko Tanaka, Rina Watanabe, Yui Akemoto, Shinji Ota, Hidezumi Kikuchi, Manabu Sawaya, Noriko Hiraga, Daisuke Chinda, Norihiro Hanabata, Tatsuya Mikami, Tadashi Shimoyama, Takenori Takahata, Masanori Tanaka, Shinsaku Fukuda
Immunological medicine 42 ( 3 ) 142 - 147 2019.9
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Influence of Helicobacter pylori Infection and Atrophic Gastritis on the Gut Microbiota in a Japanese Population.
Chikara Iino, Tadashi Shimoyama, Daisuke Chinda, Hirotake Sakuraba, Shinsaku Fukuda, Shigeyuki Nakaji
Digestion 1 - 11 2019.8
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Lifestyle Factors Rather Than Helicobacter pylori Infection or Estradiol Level are Associated With Osteopenia in Japanese Men.
Daisuke Chinda, Tadashi Shimoyama, Kaori Sawada, Chikara Iino, Hirotake Sakuraba, Shigeyuki Nakaji, Shinsaku Fukuda
American journal of men's health 13 ( 2 ) 1557988319848219 - 1557988319848219 2019.3
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Influence of gastric endoscopic submucosal dissection on serum opsonic activity measured by chemiluminescence.
Tetsu Arai, Daisuke Chinda, Tadashi Shimoyama, Kaori Sawada, Kazuki Akitaya, Kuniaki Miyazawa, Naoki Akimoto, Satoshi Sato, Shiro Hayamizu, Tetsuya Tatsuta, Hidezumi Kikuchi, Hiroto Hiraga, Manabu Sawaya, Hirotake Sakuraba, Tatsuya Mikami, Shigeyuki Nakaji, Shinsaku Fukuda
Journal of clinical biochemistry and nutrition 64 ( 2 ) 180 - 185 2019.3
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A case of nivolumab-associated colitis, which relapsed after mucosal healing and was then successfully treated with mesalazine.
Hidezumi Kikuchi, Hirotake Sakuraba, Yui Akemoto, Yasuhisa Murai, Yukari Fukutoku, Taka Asari, Tetsuya Tatsuta, Keisuke Hasui, Hiroto Hiraga, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Masanori Tanaka, Shinsaku Fukuda
Immunological medicine 42 ( 1 ) 39 - 44 2019.3
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Daidzein Intake Is Associated with Equol Producing Status through an Increase in the Intestinal Bacteria Responsible for Equol Production.
Iino C, Shimoyama T, Iino K, Yokoyama Y, Chinda D, Sakuraba H, Fukuda S, Nakaji S
Nutrients 2019.2
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Gastric Focal Neutrophil Infiltration and Wide Duodenal Gastric Foveolar Metaplasia Are Histologic Discriminative Markers for Crohn's Disease and Behçet's Disease
Akemoto Y, Sakuraba H, et al
Digestion 2018.12
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Successful treatment with tacrolimus of refractory Pyoderma Gangrenosum with pouchitis after restorative proctocolectomy for ulcerative colitis
Satake M, Sakuraba H, et al
Immunological Medicine 2018.11
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MENDEL study group. NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study
2. Kakuta Y, Kawai Y, Okamoto D, Takagawa T, Ikeya K, Sakuraba H, et al
J Gastroenterol 2018.6
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Clinical and Pharmacokinetic Factors Associated With Adalimumab-Induced Mucosal Healing in Patients With Crohn's Disease
6. Watanabe K, Matsumoto T, Hisamatsu T et al
Clin Gastroenterol Hepatol 2018.4
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5. Mikami K, Endo T, Sawada N, Igarashi G, Kimura M, Sakuraba H, Fukuda S. Inhibition of Systemic Hyaluronan Synthesis Exacerbates Murine Hepatic Carcinogenesis
Mikami K, Endo T, Sawada N, Igarashi G, Kimura M, Sakuraba H, Fukuda S
In Vivo 2018.4
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Vimentin-positive gastric adenocarcinoma arising in a hyperplastic polyp
Kawaguchi S, Yoshimura T, Sakuraba H et al
Clin J Gastroenterol 2018.2
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不明熱症例における心因性発熱の検討
櫻庭美耶子、佐藤研、櫻庭裕丈、平賀寛人、佐竹 立、福田眞作
日本心療内科学会誌 2018.2
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心不全, 呼吸不全, 急性腎障害を合併した高齢発症全身性硬化症の1例
櫻庭裕丈、金澤 洋、田坂定智、深掘耕平、宮崎真理子、鬼島 宏、玉井佳子、北川 泉、珍田大輔、大沢 弘
日本内科学会雑誌 2017.11
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Significance of measurement of serum trough level and anti-drug antibody of adalimumab as personalised pharmacokinetics in patients with Crohn's disease: a subanalysis of the DIAMOND trial
9. Nakase H, Motoya S, Matsumoto T et al
Aliment Pharmacol Ther 2017.9
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Successful adalimumab treatment and usefulness of capsule endoscopy for gut inflammation concomitant with ankylosing spondylitis
Shinji Ota, Hirotake Sakuraba, Hiroto Hiraga, Keisuke Hasui, Miwa Satake,Norihiro Hanabata, Yui Akemoto, Rina Watanabe, Nahoko Tanaka, Yoh Ishiguro, Masanori Tanaka, Shinsaku Fukuda
Mod Rheumatol 2017.2
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早期胃癌に対する内視鏡的粘膜下層剥離術の周術期におけるエネルギー代謝の検討
珍田大輔、速水史郎、柳町幸、塚本利昭、新井徹、宮澤邦昭、菊池英純、平賀寛人、澤谷学、櫻庭裕丈、三上達也、下山克、福田眞作
消化と吸収 2016.9
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Capsule Endoscopy for Differentiating Early Crohn's Disease from Behçet's
Miwa Satake, Hirotake Sakuraba, Hiroto Hiraga, Norihiro Hanabata, Noriko Hiraga, Keisuke Hasui, Shinji Ota, Yui Akemoto, Tatsuya Mikami, Yoh Ishiguro, Shinsaku Fukuda
Journal of Inflammatory Bowel Disease 2016.6
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Clinical and structural remission rates increased annually and radiographic progression was continuously inhibited during a 3-year administration of tocilizumab in patients with rheumatoid arthritis: A multi-center, prospective cohort study by the Michinoku Tocilizumab Study Group.
Hirabayashi Y, Munakata Y, Miyata M, Urata Y, Saito K, Okuno H, Yoshida M, Kodera T, Watanabe R, Miyamoto S, Ishii T, Nakazawa S, Takemori H, Ando T, Kanno T, Komagamine M, Kato I, Takahashi Y, Komatsuda A, Endo K, Murai C, Takakubo Y, Miura T, Sato Y, Ichikawa K, Konta T, Chiba N, Muryoi T, Kobayashi H, Fujii H, Sekiguchi Y, Hatakeyama A, Ogura K, Sakuraba H, Asano T, Kanazawa H, Suzuki E, Takasaki S, Asakura K, Sugisaki K, Suzuki Y, Takagi M, Nakayama T, Watanabe H, Miura K, Mori Y; Michinoku Tocilizumab Study Group.
Mod Rheumatol ( 2 ) 1 - 35 2016.3
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Prediction of maintained mucosal healing in patients with Crohn's disease under treatment with infliximab using diffusion-weighted magnetic resonance imaging.
Hirotake Sakuraba, Yoh Ishiguro, Keisuke Hasui, Hiroto Hiraga, Shinsaku Fukuda, Koichi Shibutani, Yoshihiro Takai
Digestion 89 ( 1 ) 49 - 54 2014.1
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Cyclosporine protects from apoptosis-mediated epithelial damage through epithelial STAT3 signaling pathway in DSS-induced colitis
Hirotake Sakuraba, Yoh Ishiguro, Hiroto Hiraga, Keisuke Hasui, Shinsaku Fukuda
Inflammatory Bowel Disease Suppl19 ( 13 ) S103 - S104 2013.12
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大動脈縮窄症術語２５年目に発症した人工血管十二指腸ろうの１例
岡田有史他
日本消化器病学会雑誌 109 2049 - 2057 2012.5
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[Characteristic future of intestinal Behçet's disease and simple ulcer].
Kazufumi Yamagata, Hirotake Sakuraba, Shinsaku Fukuda, Yoh Ishiguro, Masanori Tanaka
Nihon rinsho. Japanese journal of clinical medicine 70 Suppl 1 573 - 580 2012.2
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[Natural history and disease progression of Crohn's disease].
Yoh Ishiguro, Keisuke Hasui, Hirotake Sakuraba, Kazufumi Yamagata, Shinsaku Fukuda, Avako Ishiguiro
Nihon rinsho. Japanese journal of clinical medicine 70 Suppl 1 153 - 158 2012.2
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Interferon-a2b induced p21cipI/wafl degradation and cell proliferation in HeLa cells.
Ken Ota, Tomoh Matsumiya, Hirotake Sakuraba, Tadaatsu Imaizumi, Hidemi Yoshida, Shogo Kawaguchi, Shinsaku Fukuda and Kei Satoh
Cell Cycle 1 1 - 9 2010.1
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Cyclosporine Regulates Intestinal Epithelial Apoptosis via TGF-beta Related Signaling.
Satoh Y, Ishiguro Y, Sakuraba H, Kawaguchi S, Hiraga H, Fukuda S, Nakane A.
Am J Physiol Gastrointest Liver Physiol 2009.7
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Retinoic acid-inducible gene-I is constitutively expressed and involved in IFN-gamma-stimulated CXCL9-11 production in intestinal epithelial cells.
Kawaguchi S, Ishiguro Y, Imaizumi T, Mori F, Matsumiya T, Yoshida H, Ota K, Sakuraba H, Yamagata K, Sato Y, Tanji K, Haga T, Wakabayashi K, Fukuda S, Satoh K.
Immunology Letter 23 ( 123 ) 9 - 13 2009.2
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Blockade of TGF-beta accelerates mucosal destruction through epithelial cell apoptosis.
Sakuraba H, Ishiguro Y, Yamagata K, Munakata A, Nakane A.
Biochem Biophys Res Commun 359 ( 3 ) 406 - 412 2007.8
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The role of macrophage migration inhibitory factor in lethal Listeria monocytogenes infection in mice.
3. Sashinami H, Sakuraba H, Ishiguro Y, Munakata A, Nishihira J, Nakane A.
Micro Pathog 41 ( 2 ) 111 - 118 2006.12
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Combination chemotherapy with hepatic arterial infusion of 5-fluorouracil and systemic irinotecan in patients with unresectable liver metastases from colorectal cancer.
Shitara K, Munakata M, Kudo T, Kasai M, Muto O, Okada R, Mitobe S, Ishiguro A, Sakuraba H, Ikami I, Sakata Y
Gan To Kagaku Ryoho 33 ( 13 ) 2033 - 2037 2006.12
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Macrophage migration inhibitory factor has a proinflammatory activity via the p38 pathway in glucocorticoid-resistant ulcerative colitis.
4. Ishiguro Y, Ohkawara T, Sakuraba H, Yamagata K, Hiraga H, Yamaguchi S, Fukuda S, Munakata A, Nakane A,
Clin Immunol. 120 ( 3 ) 335 - 341 2006.11
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The presentation of haptenated proteins and activation of T cells in the mesenteric lymphnodes by dendritic cells in the TNBS colitis rat.
Ishiguro Y, Yamagata K, Sakuraba H, Munakata A,
Ann N Y Acad Sci. 1029 346 - 347 2004.4
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Macrophage migration inhibitory factor and activator protein-1 in ulcerative colitis.
Ishiguro Y, Yamagata K, Sakuraba H, Nakane A, Munakata A
Ann N Y Acad Sci. 1029 348 - 349 2004.4
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Transforming growth factor-beta regulates susceptibility of epithelial apoptosis in murine model ofcolitis
5. Sakuraba H, Ishiguro Y, Yamagata K, Tagawa Y, Iwakura Y, Sekikawa K, Munakata A, Nakane A.
Ann N Y Acad Sci 1029 382 - 384 2004.4
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Vaccination with nontoxic mutant toxic shock syndrome toxin 1 protects against Staphylococcus aureus infection.
Hu DL, Omoe K, Sasaki S, Sashinami H, Sakuraba H, Yokomizo Y, Shinagawa K, Nakane A.
J Infect Dis. 188 743 - 752 2003.4
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Colonic infiltration associated with myelodysplastic syndrome
9. Ishiguro A, Ishiguro Y, Uno Y, Yamagata K, Sakuraba H, Munakata A.
Gastrointest Endosc. 54 517 - 519 2001.4
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Existence of variant gammadelta T cells in Crohn's disease.
Ishiguro Y, Kanazawa H, Yamagata K, Sakuraba H, Munakata A.
Digestion 63 48 - 51 2001.4