Updated on 2024/03/12

写真a

 
TATARA Yota
 
Affiliation
Graduate School of Medicine F F

Degree

  • 博士(工学)

Professional Memberships

  • 日本結合組織学会

  • 日本糖質学会

  • 日本農芸化学会

  • 日本生化学会

Papers

  • Multiomics and artificial intelligence enabled peripheral blood-based prediction of amnestic mild cognitive impairment

    Yota Tatara, Hiromi Yamazaki, Fumiki Katsuoka, Mitsuru Chiba, Daisuke Saigusa, Shuya Kasai, Tomohiro Nakamura, Jin Inoue, Yuichi Aoki, Miho Shoji, Ikuko Motoike, Yoshinori Tamada, Katsuhito Hashizume, Mikio Shoji, Kengo Kinoshita, Koichi Murashita, Shigeyuki Nakaji, Masayuki Yamamoto, Ken Itoh

    Current Research in Translational Medicine   71 ( 1 )   103367 - 103367   2023

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  • Exploration of Malignant Characteristics in Neoadjuvant Chemotherapy-Resistant Rectal Cancer, Focusing on Extramural Lesions

    Kubota Shunsuke, Miura Takuya, Wakiya Taiichi, Yoshizawa Tadashi, Goto Shintaro, Morohashi Hajime, Sakamoto Yoshiyuki, Tatara Yota, Kijima Hiroshi, Hakamada Kenichi

    ANNALS OF SURGICAL ONCOLOGY   30 ( 12 )   7612 - 7623   2023.11

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  • ASO Visual Abstract: Exploration of Malignant Characteristics in Neoadjuvant Chemotherapy-Resistant Rectal Cancer, Focusing on Extramural Lesions

    Kubota Shunsuke, Miura Takuya, Wakiya Taiichi, Yoshizawa Tadashi, Goto Shintaro, Morohashi Hajime, Sakamoto Yoshiyuki, Tatara Yota, Kijima Hiroshi, Hakamada Kenichi

    ANNALS OF SURGICAL ONCOLOGY   30 ( 12 )   7639 - 7640   2023.11

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  • Intranasal administration of trehalose reduces α-synuclein oligomers by accelerating aggregate formation in a mouse model of multiple system atrophy

    Tanaka M., Miki Y., Mori F., Furukawa T., Shimoyama S., Tatara Y., Wakabayashi K.

    BRAIN PATHOLOGY   33   2023.9

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  • Proteomics and secreted lipidomics of mouse-derived bone marrow cells exposed to a lethal level of ionizing radiation.

    Yota Tatara, Satoru Monzen

    Scientific reports   13 ( 1 )   8802 - 8802   2023.5

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  • Purification and Characterization of Hyaluronate Lyases Produced by Two Types of Bacteria

    12 ( 4 )   99 - 104   2023.4

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  • Development of transgenic mice overexpressing mouse carbonyl reductase 1

    Minako Yokoyama, Toshitsugu Fujita, Yuka Kadonosawa, Yota Tatara, Daisuke Motooka, Masahito Ikawa, Hodaka Fujii, Yoshihito Yokoayama

    Molecular Biology Reports   50 ( 1 )   531 - 540   2023.1

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  • Novel dicarbonyl metabolic pathway via mitochondrial ES1 possessing glyoxalase III activity.

    Ito G, Tatara Y, Itoh K, Yamada M, Yamashita T, Sakamoto K, Nozaki T, Ishida K, Wake Y, Kaneko T, Fukuda T, Sugano E, Tomita H, Ozaki T

    BBA advances   3   100092   2023

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  • Oxidative Modification Status of Human Serum Albumin Caused by Chronic Low-Dose Radiation Exposure in Mamuju, Sulawesi, Indonesia

    Masaru Yamaguchi, Yota Tatara, Eka Djatnika Nugraha, Yuki Tamakuma, Yoshiaki Sato, Tomisato Miura, Masahiro Hosoda, Shinji Yoshinaga, Mukh Syaifudin, Shinji Tokonami, Ikuo Kashiwakura

    Antioxidants   11 ( 12 )   2384 - 2384   2022.12

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  • Heterogeneity of metabolic adaptive capacity affects the prognosis among pancreatic ductal adenocarcinomas

    Kanda Taishu, Wakiya Taiichi, Ishido Keinosuke, Kimura Norihisa, Fujita Hiroaki, Yoshizawa Tadashi, Goto Shintaro, Tatara Yota, Kijima Hiroshi, Hakamada Kenichi

    JOURNAL OF GASTROENTEROLOGY   57 ( 10 )   798 - 811   2022.10

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  • Serum Proteomic and Oxidative Modification Profiling in Mice Exposed to Total Body X-Irradiation

    Yamaguchi Masaru, Tatara Yota, Nugraha Eka Djatnika, Sato Yoshiaki, Miura Tomisato, Hosoda Masahiro, Syaifudin Mukh, Tokonami Shinji, Kashiwakura Ikuo

    ANTIOXIDANTS   11 ( 9 )   2022.9

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  • Sulforaphane Increase Mitochondrial Biogenesis-Related Gene Expression in the Hippocampus and Suppresses Age-Related Cognitive Decline in Mice

    Shimizu Sunao, Kasai Shuya, Yamazaki Hiromi, Tatara Yota, Mimura Junsei, Engler Mate Janos, Tanji Kunikazu, Nikaido Yoshikazu, Inoue Takuro, Suganuma Hiroyuki, Wakabayashi Koichi, Itoh Ken

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   23 ( 15 )   2022.8

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  • Detection of biological responses to low-dose radiation in humans

    Yamaguchi Masaru, Tatara Yota, Nugraha Eka Djatnika, Ramadhani Dwi, Tamakuma Yuki, Sato Yoshiaki, Miura Tomisato, Hosoda Masahiro, Yoshinaga Shinji, Syaifudin Mukh, Kashiwakura Ikuo, Tokonami Shinji

    FREE RADICAL BIOLOGY AND MEDICINE   184   196 - 207   2022.5

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  • Inducible Systemic <i>Gcn1</i> Deletion in Mice Leads to Transient Body Weight Loss upon Tamoxifen Treatment Associated with Decrease of Fat and Liver Glycogen Storage

    Jun Liu, Shuya Kasai, Yota Tatara, Hiromi Yamazaki, Junsei Mimura, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, Sato Tsubasa, Taku Ozaki, Kunikazu Tanji, Koichi Wakabayashi, Hayato Maeda, Hiroki Mizukami, Yasuhiro Shinkai, Yoshito Kumagai, Hirofumi Tomita, Ken Itoh

    International Journal of Molecular Sciences   23 ( 6 )   2022.3

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  • Eukaryotic initiation factor 2 signaling behind neural invasion linked with lymphatic and vascular invasion in pancreatic cancer.

    Wakiya Taiichi, Ishido Keinosuke, Kimura Norihisa, Nagase Hayato, Yoshizawa Tadashi, Morohashi Satoko, Fujita Hiroaki, Kanda Taishu, Tatara Yota, Saruwatari Junji, Kijima Hiroshi, Hakamada Kenichi

    Scientific reports   11 ( 1 )   21197   2021.10

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  • Capillary Electrophoresis Mass Spectrometry-Based Metabolomics of Plasma Samples from Healthy Subjects in a Cross-Sectional Japanese Population Study

    Hiroyuki Yamamoto, Makoto Suzuki, Rira Matsuta, Kazunori Sasaki, Moon-Il Kang, Kenjiro Kami, Yota Tatara, Ken Itoh, Shigeyuki Nakaji

    Metabolites   11 ( 5 )   2021.5

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  • HER2-positive breast cancer that resists therapeutic drugs and ionizing radiation releases sphingomyelin-based molecules to circulating blood serum.

    Satoru Monzen, Yota Tatara, Yasushi Mariya, Mitsuru Chiba, Andrzej Wojcik, Lovisa Lundholm

    Molecular and clinical oncology   13 ( 6 )   70 - 70   2020.12

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  • Essential hyaluronan structure for binding with hyaluronan-binding protein (HABP) determined by glycotechnological approach.

    Suto S, Kakizaki I, Tatara Y, Endo M

    Carbohydrate polymers   251   116989 - 116989   2020.8

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  • Proteomic changes by radio-mitigative thrombopoietin receptor agonist romiplostim in the blood of mice exposed to lethal total-body irradiation.

    Teruki Nishida, Masaru Yamaguchi, Yota Tatara, Ikuo Kashiwakura

    International journal of radiation biology   96 ( 9 )   1125 - 1134   2020.7

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  • Blockade of PAR-1 Signaling Attenuates Cardiac Hypertrophy and Fibrosis in Renin-Overexpressing Hypertensive Mice.

    Yoshikazu Yokono, Kenji Hanada, Masato Narita, Yota Tatara, Yousuke Kawamura, Naotake Miura, Kazutaka Kitayama, Masamichi Nakata, Masashi Nozaka, Tomo Kato, Natsumi Kudo, Michiko Tsushima, Yuichi Toyama, Ken Itoh, Hirofumi Tomita

    Journal of the American Heart Association   9 ( 12 )   e015616   2020.6

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  • Regulation of Nrf2 by Mitochondrial Reactive Oxygen Species in Physiology and Pathology.

    Yota Tatara

    Biomolecules   10 ( 2 )   2020.2

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  • 放射線抵抗性を示すHER2陽性乳癌患者の血清中Sphingomyelin関連代謝物の濃度変化の特徴

    門前 暁, 多田羅 洋太, 千葉 満, 真里谷 靖

    臨床病理   67 ( 補冊 )   167 - 167   2019.10

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  • Novel roles of glycosaminoglycans in the degradation of type I collagen by cathepsin K.

    Tatara Y, Suto S, Itoh K

    Glycobiology   27 ( 12 )   1089 - 1098   2017.12

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  • A mechanism for evasion of CTL immunity by altered O-glycosylation of HLA class I.

    Yoneyama Mihoko Sutoh, Tobisawa Yuki, Hatakeyama Shingo, Sato Misaki, Tone Kiyoshi, Tatara Yota, Kakizaki Ikuko, Funyu Tomihisa, Fukuda Minoru, Hoshi Senji, Ohyama Chikara, Tsuboi Shigeru

    Journal of Biochemistry   161 ( 6 )   479 - 492   2017.6

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  • Chondroitin sulfate cluster involves in the binding specificity to collagen

    Tatara Yota

    89 ( 2 )   290 - 292   2017.4

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  • AMBRA1, a novel α-synuclein-binding protein, is implicated in the pathogenesis of multiple system atrophy

    Miki Yasuo, Tanji Kunikazu, Mori Fumiaki, Tatara Yota, Utsumi Jun, Sasaki Hidenao, Kakita Akiyoshi, Takahashi Hitoshi, Fimia Gian Maria, Wakabayashi Koichi

    Brain Pathology   28 ( 1 )   28 - 42   2017.3

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  • クラスター効果による糖鎖の相互作用

    多田羅 洋太

    化学と生物   54 ( 11 )   789 - 790   2016

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  • Preparation of proteoglycan from salmon nasal cartilage under nondenaturing conditions.

    Tatara Y, Suto S, Sasaki Y, Endo M

    79 ( 10 )   1615 - 1618   2015.10

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  • Preparation of proteoglycan from salmon nasal cartilage under nondenaturing conditions.

    Bioscience, Biotechnology, and Biochemistry   79 ( 10 )   1615 - 1618   2015.5

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  • Biochemical and atomic force microscopic characterization of salmon nasal cartilage proteoglycan (vol 103, pg 538, 2014)

    Kakizaki Ikuko, Mineta Takashi, Sasaki Mana, Tatara Yota, Makino Eiji, Kato Yoji

    CARBOHYDRATE POLYMERS   115   805 - 805   2015.1

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  • Chondroitin sulfate cluster of epiphycan from salmon nasal cartilage defines binding specificity to collagens.

    Tatara Y, Kakizaki I, Suto S, Ishioka H, Negishi M, Endo M

    Glycobiology   25 ( 5 )   557 - 69   2014.12

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  • Biochemical and atomic force microscopic characterization of salmon nasal cartilage proteoglycan.

    Carbohydrate polymers   103   538 - 549   2014.3

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  • Biochemical and atomic force microscopic characterization of salmon nasal cartilage proteoglycan.

    Yota Tatara

    Carbohydrate polymers   103   538 - 549   2014.3

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  • Synthesis of N-acetyl Glucosamine Analogs as Inhibitors for Hyaluronan Biosynthesis

    Journal of Carbohydrate Chemistry   32 ( 5-6 )   392 - 409   2013.9

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  • Epiphycan from salmon nasal cartilage is a novel type of large leucine-rich proteoglycan.

    Glycobiology   23 ( 8 )   993 - 1003   2013.8

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  • Epiphycan from salmon nasal cartilage is a novel type of large leucine-rich proteoglycan.

    Tatara Y, Kakizaki I, Kuroda Y, Suto S, Ishioka H, Endo M

    23 ( 8 )   993 - 1003   2013.8

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  • Synthesis of N-acetyl Glucosamine Analogs as Inhibitors for Hyaluronan Biosynthesis

    Wasonga Gilbert, Tatara Yota, Kakizaki Ikuko, Huang Xuefei

    JOURNAL OF CARBOHYDRATE CHEMISTRY   32 ( 5-6 )   392 - 409   2013.7

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  • Hyaluronan-chondroitin hybrid oligosaccharides as new life science research tools

    Biochemical and Biophysical Research Communications   423 ( 2 )   344 - 349   2012.6

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  • Hyaluronan-chondroitin hybrid oligosaccharides as new life science research tools.

    Kakizaki I, Suto S, Tatara Y, Nakamura T, Endo M

    423 ( 2 )   344 - 349   2012.6

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  • Identification of proteoglycan from salmon nasal cartilage.

    Archives of Biochemistry and Biophysics   506 ( 1 )   58 - 65   2011.2

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  • Identification of proteoglycan from salmon nasal cartilage.

    Kakizaki I, Tatara Y, Majima M, Kato Y, Endo M

    506 ( 1 )   58 - 65   2011.2

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  • [Review: Symposium on Amylases and Related Enzymes] Catalytic Structure of GH47 α-Mannosidase

    Yoshida Takashi, Tatara Yohta, Lobsanov Yuri D., Howell Lynne P.

    Bulletin of Applied Glycoscience   1 ( 2 )   168 - 173   2011

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  • Identification of Pin1-binding Phosphorylated Proteins in Mouse Brain.

    Bioscience, Biotechnology, and Biochemistry   74 ( 12 )   2480 - 2483   2010.12

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  • Identification of Pin1-Binding Phosphorylated Proteins in the Mouse Brain

    TATARA Yota, TERAKAWA Takahiro, UCHIDA Takafumi

    Bioscience, Biotechnology, and Biochemistry   74 ( 12 )   2480 - 2483   2010

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  • Catalytic structure of GH47 α-mannosidases

    Yoshida Takashi, Tatara Youta, D. Robsanov Yuri, Howell Lynne

    Journal of Applied Glycoscience Supplement   2010 ( 0 )   129 - 129   2010

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  • Dipentamethylene thiuram monosulfide is a novel inhibitor of Pin1.

    Yota Tatara, Yi-Chin Lin, Yoshimasa Bamba, Tadashi Mori, and Takafumi Uchida

    Biochemical and Biophysical Research Communications   384 ( 3 )   394 - 398   2009.7

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  • Dipentamethylene thiuram monosulfide is a novel inhibitor of Pin1.

    Tatara Y, Lin YC, Bamba Y, Mori T, Uchida T

    384 ( 3 )   394 - 398   2009.7

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  • Use of a Real-time Fluorescence Monitoring System for High-Throughput Screening for Prolyl Isomerase Inhibitors.

    Tadashi Mori, Seima Itami, Tomotaka Yanagi, Yota Tatara, Mari Takamiya, and Takafumi Uchida

    Journal of Biomolecular Screening   14   419 - 424   2009.4

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  • Use of a real-time fluorescence monitoring system for high-throughput screening for prolyl isomerase inhibitors.

    Mori T, Itami S, Yanagi T, Tatara Y, Takamiya M, Uchida T

    14 ( 4 )   419 - 424   2009.4

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  • Pseudomonas fluorescens proliferates in a mouse organ homogenate at low temperature.

    Yota Tatara, Takahiro Terakawa, Youhei Yamagata, and Takafumi Uchida

    International Journal of Molecular Medicine   21   621 - 626   2008.5

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  • Pseudomonas fluorescens proliferates in a mouse organ homogenate at low temperature.

    Tatara Y, Terakawa T, Yamagata Y, Uchida T

    International journal of molecular medicine   21 ( 5 )   621 - 6   2008.5

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  • Pseudomonas fluorescens proliferates in a mouse organ homogenate at low temperature

    Tatara Yota, Terakawa Takahiro, Yamagata Youhei, Uchida Takafumi

    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE   21 ( 5 )   621 - 626   2008.5

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  • Pseudomonas fluorescens proliferates in a mouse organ homogenate at low temperature.

    Tatara Y, Terakawa T, Yamagata Y, Uchida T

    International journal of molecular medicine   21 ( 5 )   621 - 6   2008.5

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  • Novel Functions of prolyl isomerase Pin1.

    Hirotada Akiyama, Yota Tatara, and Takafumi Uchida

    Tohoku journal of agricultural research   58 ( 4 )   147 - 156   2008.3

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  • Acid activation of protyrosinase from Aspergillus oryzae: homo-tetrameric protyrosinase is converted to active dimers with an essential intersubunit disulfide bond at acidic pH.

    Yota Tatara, Takeshi Namba, Youhei Yamagata, Takashi Yoshida, Takafumi Uchida, and Eiji Ichishima

    Pigment Cell & Melanoma Research   21 ( 1 )   89 - 96   2008.2

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  • Acid activation of protyrosinase from Aspergillus oryzae: homo-tetrameric protyrosinase is converted to active dimers with an essential intersubunit disulfide bond at acidic pH.

    Tatara Y, Namba T, Yamagata Y, Yoshida T, Uchida T, Ichishima E

    PIGMENT CELL & MELANOMA RESEARCH   21 ( 1 )   89 - 96   2008.2

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  • A single free cysteine residue and disulfide bond contribute to the thermostability of Aspergillus saitoi 1,2-alpha-mannosidase.

    Yota Tatara, Takashi Yoshida, and Eiji Ichishima

    Bioscience Biotechnology and Biochemistry   69 ( 11 )   2101 - 2108   2005.11

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  • A single free cysteine residue and disulfide bond contribute to the thermostability of Aspergillus saitoi 1,2-alpha-mannosidase

    Tatara Y, Yoshida T, Ichishima E

    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   69 ( 11 )   2101 - 2108   2005.11

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  • Grifolisin, a member of the sedolisin family produced by the fungus Grifola frondosa.

    Suzuki N, Nishibori K, Oodaira Y, Kitamura S, Michigami K, Nagata K, Tatara Y, Lee BR, Ichishima E

    66 ( 9 )   983 - 990   2005.5

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  • Grifolisin, a member of the sedolisin family produced by the fungus Grifola frondosa.

    Norio Suzuki, Kohzoh Nishibori, Yasuo Oodaira, Shin-ichi Kitamura, Kenji Michigami, Keiko Nagata, Yota Tatara, Byung Rho Lee, and Eiji Ichishima

    Phytochemistry   66 ( 9 )   983 - 990   2005.4

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  • A Single Free Cysteine Residue and Disulfide Bond Contribute to the Thermostability of Aspergillus saitoi 1,2-.ALPHA.-Mannosidase

    TATARA Yota, YOSHIDA Takashi, ICHISHIMA Eiji

    Bioscience, Biotechnology, and Biochemistry   69 ( 11 )   2101 - 2108   2005

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  • Cysteine residues of Aspergillus saitoi 1,2-alpha-mannosidase contribute to thermostability

    Tatara Y, Lee BR, Yoshida T, Ichishima E

    GLYCOBIOLOGY   14 ( 11 )   1111 - 1112   2004.11

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  • Identification of catalytic residues of Ca2+-independent 1,2-alpha-D-mannosidase from Aspergillus saitoi by site-directed mutagenesis.

    Tatara Y, Lee BR, Yoshida T, Takahashi K, Ichishima E

    278 ( 28 )   25289 - 25294   2003.7

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  • Identification of catalytic residues of Ca2+-independent 1,2-alpha-D-mannosidase from Aspergillus saitoi by site-directed mutagenesis.

    Yota Tatara, Byung Rho Lee, Takashi Yoshida, Koji Takahashi, and Eiji Ichishima

    The Journal of Biological Chemistry   278 ( 28 )   25289 - 25294   2003.4

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Review Papers

  • Emerging role of GCN1 in disease and homeostasis

    Yota Tatara, Shuya Kasai, Daichi Kokubu, Tadayuki Tsujita, Junsei Mimura, Ken Itoh

    International Journal of Molecular Sciences   25 ( 5 )   2998   2024.3

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  • Regulation of Nrf2 by Mitochondrial Reactive Oxygen Species in Physiology and Pathology.

    Kasai S, Shimizu S, Tatara Y, Mimura J, Itoh K

    Biomolecules   10 ( 2 )   E320 - E320   2020.2

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  • コラーゲンとの結合特異性にも関与する糖鎖のクラスター効果

    多田羅 洋太

    生化学会誌   89 ( 2 )   290 - 292   2017.4

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (bulletin of university, research institution)   Publisher:日本生化学会   Kind of work:Single Work  

  • Interaction of sugar chains through cluster effect

    TATARA Yota

    KAGAKU TO SEIBUTSU   54 ( 11 )   789 - 790   2016.10

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:INTERNATIONAL ACADEMIC PUBLISHING CO., LTD.   Kind of work:Single Work  

  • GH 47 α-マンノシダーゼの触媒構造について

    吉田 孝, 多田羅 洋太, Yuri D. Lobsanov, and Lynne P. Howell

    日本応用糖質科学会誌   1 ( 2 )   168 - 173   2011.2

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (bulletin of university, research institution)   Publisher:日本応用糖質科学会   Kind of work:Joint Work  

  • 麹菌チロシナーゼの酸活性化機構

    多田羅洋太, 多田羅洋太, 難波剛, 山形洋平, 吉田孝, 内田隆史, 一島英治, 一島英治

    日本醸造協会誌   103 ( 10 )   2008

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Kind of work:Joint Work  

    J-GLOBAL

  • 麹菌チロシナーゼの酸活性化機構

    多田羅洋太, 多田羅洋太, 難波剛, 山形洋平, 吉田孝, 内田隆史, 一島英治, 一島英治

    日本醸造学会大会講演要旨集   2008   2008

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    Language:English   Publishing type:Rapid communication, short report, research note, etc. (scientific journal)   Kind of work:Joint Work  

    J-GLOBAL

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Awards

  • Excellent Article Award of The Japanese Biochemical Society, Tohoku Branch

    2016.05

Social Activities

  • プレスリリース

    2017.11