Updated on 2024/05/30

写真a

 
CHIBA MITSURU
 
Affiliation
Health Sciences Health Sciences(Doctoral Course) Department of Bioscience and Laboratory Medicine
Laboratory Phone number
+81-172-39-5965
Laboratory Fax number
+81-172-39-5965

Degree

  • Ph.D. in Medicine, Doctor of Medical Science

  • 修士(保健学),弘前大学

  • 学士(保健学),弘前大学

Research Interests

  • cell to cell communication

  • Extracellular vesicles

  • biomarker

  • Exosome

  • microRNA

  • gene expression

Research Areas

  • Life Science / Genome biology

  • Life Science / Molecular biology

  • Others / Others

  • Life Science / Cell biology

  • Life Science / Pathological biochemistry

  • Life Science / Molecular biology

  • Life Science / Genome biology

  • Life Science / Tumor biology

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Professional Memberships

  • Japanese Association of Medical Technologists (JAMT)

  • Japanese Association of Medical Technology Education (JAMTE)

  • Japan Society of Clinical Chemistry (JSCC)

  • Japanese Society of Laboratory Medicine (JSLM)

  • The Molecular Biology Socirty of Japan (MBSJ)

  • Japanese Cancer Association (JCA)

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Papers

  • Serum miR‑29 is increased in mice with early liver fibrosis.

    Kana Matsumoto, Yuhei Ohsugi, Chisa Tayama, Momone Hayashi, Yumiko Kato, Mizuho Ohashi, Mitsuru Chiba

    Experimental and therapeutic medicine   28 ( 1 )   285 - 285   2024.7

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  • The report of training course for biological effect by ionizing radiation-CELET course 2023-

    Keisuke Yamamoto, Mitsuru Chiba, Satoru Monzen

    Journal of Health Sciences Research   14 ( 2 )   65 - 71   2024.3

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  • Extracellular miRNAs in the serum and feces of mice exposed to high‑dose radiation

    Mitsuru Chiba, Haruka Uehara, Haruka Kuwata, Ikumi Niiyama

    Biomedical Reports   20 ( 3 )   55   2024.2

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  • Examination and comparison of the RNA extraction methods using mouse serum

    Keisuke Yamamoto, Mitsuru Chiba

    Biomedical Reports   20 ( 3 )   51   2024.1

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  • Changes in cognitive ability and serum microRNA levels during aging in mice

    Keisuke Yamamoto, Kohta Miyano, Minami Fujita, Wakana Kurata, Hiroya Ohta, Kana Matsumoto, Mitsuru Chiba

    Experimental and Therapeutic Medicine   27 ( 3 )   120   2024.1

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  • Analysis of gene expression changes during lipid droplet formation in HepG2 human liver cancer cells

    Mitsuru Chiba, Yuhei Ohsugi, Kana Matsumoto, Chisa Tayama

    Medicine International   4 ( 1 )   7   2024.1

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  • 技術講座 一般 尿比重-その測定原理,臨床的意義を徹底解説

    千葉 満

    検査と技術   51 ( 11 )   1246 - 1250   2023.11

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  • 大腸がん細胞株HCT-116にて発見された放射線損傷特異マイクロRNA遺伝子発現の特徴

    佐藤 亮介, 門前 暁, 上野 達也, 千葉 満, 真里谷 靖, ヴォイチク・アンドレイ

    日本放射線技術学会総会学術大会予稿集   79回   222 - 222   2023.3

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  • Multiomics and artificial intelligence enabled peripheral blood-based prediction of amnestic mild cognitive impairment

    Yota Tatara, Hiromi Yamazaki, Fumiki Katsuoka, Mitsuru Chiba, Daisuke Saigusa, Shuya Kasai, Tomohiro Nakamura, Jin Inoue, Yuichi Aoki, Miho Shoji, Ikuko Motoike, Yoshinori Tamada, Katsuhito Hashizume, Mikio Shoji, Kengo Kinoshita, Koichi Murashita, Shigeyuki Nakaji, Masayuki Yamamoto, Ken Itoh

    Current Research in Translational Medicine   71 ( 1 )   103367 - 103367   2022.10

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  • 放射線治療抵抗性を示すHER2陽性乳癌のスフィンゴミエリン代謝の特徴

    門前 暁, 千葉 満, 真里谷 靖

    日本臨床検査医学会誌   70 ( 補冊 )   144 - 144   2022.10

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  • 子ども期の放射線被ばくに特徴的な血清中microRNA解析

    千葉 満, 松本 佳菜, 門前 暁, 真里谷 靖

    日本臨床検査医学会誌   70 ( 補冊 )   261 - 261   2022.10

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  • Dose-dependent expression of extracellular microRNAs in HCT116 colorectal cancer cells exposed to high-dose-rate ionising radiation.

    Satoru Monzen, Tatsuya Ueno, Mitsuru Chiba, Yuki Morino, Yasushi Mariya, Andrzej Wojcik, Lovisa Lundholm

    Molecular and clinical oncology   16 ( 1 )   19 - 19   2022.1

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  • Hepatic gene expression and functional changes associated with nonalcoholic steatohepatitis

    Kana Matsumoto, Yumiko Kato, Momone Hayashi, Risa MiuraI, Satoru Monzen, Mitsuru Chiba

    Molecular Medicine Reports   in press ( 5 )   2022

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  • 研究者の最新動向 メタボローム解析を用いたHER2陽性乳がん術後補助療法期間における予後予測バイオマーカー

    門前 暁, 多田羅 洋太, 千葉 満, 真里谷 靖

    Precision Medicine   4 ( 13 )   1238 - 1241   2021.12

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  • 多層オミックスと機械学習による軽度認知障害の予測モデルの構築

    多田羅 洋太, 中村 智洋, 千葉 満, 三枝 大輔, 山嵜 博未, 勝岡 史城, 葛西 秋宅, 川瀬 倫子, 本間 リナ, 松田 りら, 藤本 哲太, 荘司 美穂, 元池 育子, 玉田 嘉紀, 橋爪 克仁, 東海林 幹夫, 木下 賢吾, 伊東 健

    Dementia Japan   35 ( 4 )   660 - 660   2021.10

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  • HER2-positive breast cancer that resists therapeutic drugs and ionizing radiation releases sphingomyelin-based molecules to circulating blood serum.

    Satoru Monzen, Yota Tatara, Yasushi Mariya, Mitsuru Chiba, Andrzej Wojcik, Lovisa Lundholm

    Molecular and clinical oncology   13 ( 6 )   70 - 70   2020.12

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  • HER2-positive breast cancer that resists therapeutic drugs and ionizing radiation releases sphingomyelin-based molecules to circulating blood serum.

    Satoru Monzen, Yota Tatara, Yasushi Mariya, Mitsuru Chiba, Andrzej Wojcik, Lovisa Lundholm

    Molecular and clinical oncology   13 ( 6 )   70 - 70   2020.12

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  • 肝細胞癌体幹部定位放射線療法におけるradiation-induced liver disease

    真里谷 靖, 門前 暁, 千葉 満

    臨床病理   68 ( 補冊 )   252 - 252   2020.10

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  • 多層オミックス解析による認知症の早期発見のためのバイオマーカー探索

    多田羅 洋太, 中村 智洋, 山嵜 博未, 勝岡 史城, 千葉 満, 三枝 大輔, 葛西 秋宅, 伊東 健

    JSBMS Letters   45 ( Suppl. )   32 - 32   2020.8

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  • Changes in miRNA expressions in the injured small intestine of mice following high‑dose radiation exposure.

    Mitsuru Chiba, Haruka Uehara, Ikumi Niiyama, Haruka Kuwata, Satoru Monzen

    Molecular medicine reports   21 ( 6 )   2452 - 2458   2020.6

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  • Changes in miRNA expressions in the injured small intestine of mice following high‑dose radiation exposure.

    Mitsuru Chiba, Haruka Uehara, Ikumi Niiyama, Haruka Kuwata, Satoru Monzen

    Molecular medicine reports   21 ( 6 )   2452 - 2458   2020.4

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  • 4-methylumbelliferone inhibits clonogenic potency by suppressing high molecular weight-hyaluronan in fibrosarcoma cells.

    Kazuki Hasegawa, Ryo Saga, Rei Takahashi, Roman Fukui, Mitsuru Chiba, Kazuhiko Okumura, Eichi Tsuruga, Yoichiro Hosokawa

    Oncology letters   19 ( 4 )   2801 - 2808   2020.4

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  • 地方における保健医療技術職へ外国人就労者が増大した際の医療環境変化の考察~多民族国家スウェーデンを参考に~

    門前 暁、森野 友貴、千葉 満、Wojcik Andrzej

    保健科学研究   10 ( 2 )   35 - 40   2020.3

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  • Effects of voluntary and forced exercises on motor function recovery in intracerebral hemorrhage rats.

    Chihiro Sato, Kunikazu Tanji, Shuji Shimoyama, Mitsuru Chiba, Misaki Mikami, Shuhei Koeda, Koshi Sumigawa, Kazuki Akahira, Junko Yamada

    Neuroreport   31 ( 2 )   189 - 196   2020.1

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  • Effects of voluntary and forced exercises on motor function recovery in intracerebral hemorrhage rats.

    Chihiro Sato, Kunikazu Tanji, Shuji Shimoyama, Mitsuru Chiba, Misaki Mikami, Shuhei Koeda, Koshi Sumigawa, Kazuki Akahira, Junko Yamada

    Neuroreport   31 ( 2 )   189 - 196   2020.1

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  • バングラデシュにおける蔓延感染症と教育・医療現場を体験して

    山内可南子,吉岡翔,坂本倭,吉田仁美,田澤一紘,千葉満, Chowdhury Ahsan, 藤岡美幸

    青臨技会誌   44   60 - 63   2019.12

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  • 弘前大学検査技術科学専攻における過去11年の求人情報

    山内可南子、千葉満、吉岡治彦、武尾照子、渡邉純、丹藤雄介、伊藤巧一

    臨床検査学教育   12 ( 1 )   1 - 6   2019.11

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  • 少数個転移性肝腫瘍に対する体幹部定位放射線療法に伴うradiation-induced liver diseaseの検討

    真里谷 靖, 山田 恭吾, 門前 暁, 千葉 満

    臨床病理   67 ( 補冊 )   256 - 256   2019.10

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  • Predictive Biomarker for the Detection of Ionizing Radiation Toxicity

    Satoru Monzen, Tatsuya Ueno, Mitsuru Chiba, Yasushi Mariya

    Nihon Hoshasen Gijutsu Gakkai zasshi   75 ( 5 )   480 - 485   2019.5

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  • Injured pancreatic β cells enhance the release of miR-375-3p into the extracellular space.

    Mitsuru Chiba, Ikumi Niiyama, Haruka Uehara, Haruka Kuwata

    Experimental and therapeutic medicine   17 ( 4 )   2815 - 2820   2019.4

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  • Injured pancreatic β cells enhance the release of miR-375-3p into the extracellular space.

    Mitsuru Chiba, Ikumi Niiyama, Haruka Uehara, Haruka Kuwata

    Experimental and therapeutic medicine   17 ( 4 )   2815 - 2820   2019.4

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  • Malondialdehyde: a urinary toxic biomarker for unexpected exposure to high-dose ionizing radiation

    Satoru Monzen, Mitsuru Chiba, Yasushi Mariya

    Rinsho Byori   67 ( 3 )   212 - 215   2019.3

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  • Regulation of radiosensitivity by 4-methylumbelliferone via the suppression of interleukin-1 in fibrosarcoma cells.

    Ryo Saga, Kazuki Hasegawa, Kosho Murata, Mitsuru Chiba, Toshiya Nakamura, Kazuhiko Okumura, Eichi Tsuruga, Yoichiro Hosokawa

    Oncology letters   17 ( 3 )   3555 - 3561   2019.3

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  • Regulation of radiosensitivity by 4-methylumbelliferone via the suppression of interleukin-1 in fibrosarcoma cells.

    Ryo Saga, Kazuki Hasegawa, Kosho Murata, Mitsuru Chiba, Toshiya Nakamura, Kazuhiko Okumura, Eichi Tsuruga, Yoichiro Hosokawa

    Oncology letters   17 ( 3 )   3555 - 3561   2019.3

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  • 15. Predictive Biomarker for the Detection of Ionizing Radiation Toxicity

    Monzen Satoru, Ueno Tatsuya, Chiba Mitsuru, Mariya Yasushi

    Japanese Journal of Radiological Technology   75 ( 5 )   480 - 485   2019

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  • Malondialdehyde: a urinary toxic biomarker for unexpected exposure to high-dose ionizing radiation

    門前 暁, 千葉 満

    Rinsho Byori   67   212 - 215   2019

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  • Cell‑to‑cell communication via extracellular vesicles among human pancreatic cancer cells derived from the same patient.

    Mitsuru Chiba, Shiori Kubota, Ayaka Sakai, Satoru Monzen

    Molecular medicine reports   18 ( 4 )   3989 - 3996   2018.10

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  • Exosomes released from pancreatic cancer cells enhance angiogenic activities via dynamin-dependent endocytosis in endothelial cells in vitro.

    8 ( 1 )   11972 - 11972   2018.8

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  • A radioresistant fraction of acute promyelocytic leukemia cells exhibit CD38 cell-surface antigen and mRNA expression.

    Satoru Monzen, Mitsuru Chiba, Tatsuya Ueno, Yuki Morino, Kenji Terada, Hiroki Yamaya, Yoichiro Hosokawa

    Oncology letters   15 ( 5 )   6709 - 6714   2018.5

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  • Screening for Biological Marker of Dose-optimization in Cancer Radiotherapy

    Tatsuya Ueno, Satoru Monzen, Mitsuru Chiba, Yuki Morino, Yoichiro Hosokawa

    Nihon Hoshasen Gijutsu Gakkai zasshi   74 ( 5 )   459 - 464   2018.5

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  • Screening for Biological Marker of Dose-optimization in Cancer Radiotherapy

    Ueno Tatsuya, Monzen Satoru, Chiba Mitsuru, Morino Yuki, Hosokawa Yoichiro

    Japanese Journal of Radiological Technology   74 ( 5 )   459 - 464   2018.5

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  • Urinal biomarker, 8-Hydroxy-2'-Deoxyguanosine, for unexpected exposure dose of ionizing radiation

    Monzen Satoru, Terada Kenji, Morino Yuki, Chiba Mitsuru

    Cytometry Research   28 ( 1 )   41 - 45   2018.5

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  • Serum miR-375-3p increase in mice exposed to a high dose of ionizing radiation.

    Mitsuru Chiba, Satoru Monzen, Chihiro Iwaya, Yuri Kashiwagi, Sunao Yamada, Yoichiro Hosokawa, Yasushi Mariya, Toshiya Nakamura, Andrzej Wojcik

    Scientific Reports   8 ( 1 )   1302   2018.1

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  • Anthocyanin‑rich blackcurrant extract inhibits proliferation of the MCF10A healthy human breast epithelial cell line through induction of G0/G1 arrest and apoptosis.

    Naoki Nanashima, Kayo Horie, Mitsuru Chiba, Manabu Nakano, Hayato Maeda, Toshiya Nakamura

    Molecular Medicine Reports   16 ( 5 )   6134 - 6141   2017.11

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  • Antisense RNA transcripts in the blood may be novel diagnostic markers for colorectal cancer.

    Tomohiro Kurokawa, Keisuke Kohno, Kentaro Nagai, Mitsuru Chiba, Sugiru Pak, Soichiro Murata, Kiyoshi Fukunaga, Hiroshi Yasue, Nobuhiro Ohkohchi

    Oncology Letters   14 ( 3 )   3487 - 3493   2017.9

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  • Anti-tumor and anti-invasion effects of a combination of 4-methylumbelliferone and ionizing radiation in human fibrosarcoma cells.

    Ryo Saga, Satoru Monzen, Mitsuru Chiba, Hironori Yoshino, Toshiya Nakamura, Yoichiro Hosokawa

    Oncology Letters   13 ( 1 )   410 - 416   2017.1

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  • Report on the 2nd Educational Symposium on RADIATION AND HEALTH by Young Scientists (ESRAH2015)

    Radiation environment and medicine : covering a broad scope of topics relevant to environmental and medical radiation research   5 ( 1 )   65 - 71   2016.3

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  • Genetic network profiles associated with established resistance to ionizing radiation in acute promyelocytic leukemia cells and their extracellular vesicles.

    Satoru Monzen, Mitsuru Chiba, Yoichiro Hosokawa

    Oncology Reports   35 ( 2 )   749 - 756   2016.2

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  • Exosomes derived from SW480 colorectal cancer cells promote cell migration in HepG2 hepatocellular cancer cells via the mitogen-activated protein kinase pathway.

    Mitsuru Chiba, Narumi Watanabe, Miki Watanabe, Maki Sakamoto, Akika Sato, Mizuki Fujisaki, Shiori Kubota, Satoru Monzen, Atsushi Maruyama, Naoki Nanashima, Ikuo Kashiwakura, Toshiya Nakamura

    International journal of oncology   48 ( 1 )   305 - 312   2016.1

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  • Phytoestrogenic activity of blackcurrant (Ribes nigrum) anthocyanins is mediated through estrogen receptor alpha.

    Naoki Nanashima, Kayo Horie, Toshiko Tomisawa, Mitsuru Chiba, Manabu Nakano, Toshifumi Fujita, Hayato Maeda, Maiko Kitajima, Shizuka Takamagi, Daishi Uchiyama, Jun Watanabe, Toshiya Nakamura, Yoji Kato

    Molecular nutrition & food research   59 ( 12 )   2419 - 2431   2015.12

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  • Cytogenetic dosimetry by micronucleus assay using peripheral blood cells is modified by thyroid hormones.

    S Monzen, Y Mariya, A Nakamura, C Kawamura, K Taira, M Chiba, Y Takai

    Radiation protection dosimetry   167 ( 1-3 )   321 - 325   2015.11

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  • Detection of natural antisense non-coding RNAs transcribed from Ncam1 in mice tissues at several developmental stages.

    Mitsuru Chiba

    Biomedical reports   3 ( 5 )   663 - 667   2015.9

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  • mRNA Expression Profiles in Human Lymphoid Progenitor Cell are Modified by High-dose Ionizing Radiation

    Radiation emergency medicine   4 ( 2 )   35 - 39   2015.8

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  • Report on the 1st Educational Symposium on RADIATION AND HEALTH by Young Scientists (ESRAH2014)

    Radiation emergency medicine   4 ( 2 )   58 - 62   2015.8

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  • Predictive factors of cytotoxic damage in radioactive iodine treatment of differentiated thyroid cancer patients.

    Satoru Monzen, Yasushi Mariya, Andrzej Wojcik, Chika Kawamura, Ayumi Nakamura, Mitsuru Chiba, Masahiro Hosoda, Yoshihiro Takai

    Molecular and Clinical Oncology   3 ( 3 )   692 - 698   2015.5

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  • 1,8-Cineole Ameliorates Steatosis of Pten Liver Specific KO Mice via Akt Inactivation.

    Soichiro Murata, Koichi Ogawa, Takashi Matsuzaka, Mitsuru Chiba, Ken Nakayama, Kenichi Iwasaki, Tomohiro Kurokawa, Naoki Sano, Tomohito Tanoi, Nobuhiro Ohkohchi

    International Journal of Molecular Sciences   16 ( 6 )   12051 - 12063   2015.3

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  • Discovery, primary, and crystal structures and capacitation-related properties of a prostate-derived heparin-binding protein WGA16 from boar sperm.

    Estelle Garénaux, Mayumi Kanagawa, Tomoyuki Tsuchiyama, Kazuki Hori, Takeru Kanazawa, Ami Goshima, Mitsuru Chiba, Hiroshi Yasue, Akemi Ikeda, Yoshiki Yamaguchi, Chihiro Sato, Ken Kitajima

    The Journal of Biological Chemistry   290 ( 9 )   5484 - 5501   2015.2

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  • Secretion of small/microRNAs including miR-638 into extracellular spaces by sphingomyelin phosphodiesterase 3.

    Shiori Kubota, Mitsuru Chiba, Miki Watanabe, Maki Sakamoto, Narumi Watanabe

    Oncology Reports   33 ( 1 )   67 - 73   2015.1

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  • Demonstration of Epidermal Growth Factor-like Activity in Salmon Cartilage Proteoglycan

    5   93 - 104   2015

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  • Mitigative Effects of a Combination of Multiple Pharmaceutical Drugs on the Survival of Mice Exposed to Lethal Ionizing Radiation.

    Tokuhisa Hirouchi, Koichi Ito, Manabu Nakano, Satoru Monzen, Hironori Yoshino, Mitsuru Chiba, Masaharu Hazawa, Akira Nakano, Junya Ishikawa, Masaru Yamaguchi, Kimio Tanaka, Ikuo Kashiwakura

    Current pharmaceutical biotechnology   17 ( 2 )   190 - 199   2015

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  • Mode of swine hepatitis E virus infection and replication in primary human hepatocytes.

    Yukio Oshiro, Hiroshi Yasue, Kazuhiro Takahashi, Shinji Hattori, Shoji Ideno, Takeru Urayama, Mitsuru Chiba, Suguru Osari, Tadasuke Naito, Kaoru Takeuchi, Kyosuke Nagata, Nobuhiro Ohkohchi

    The Journal of General Virology   95 ( Pt 12 )   2677 - 2682   2014.12

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  • Differential expression of natural antisense transcripts during liver development in embryonic mice.

    Mitsuru Chiba

    Biomedical Reports   2 ( 6 )   918 - 922   2014.11

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  • Long-lasting Radioprotective Effects of a Combination of Pharmaceutical Drugs on the Survival of Mice Exposed to Lethal Ionizing Radiation

    Radiation emergency medicine   3 ( 1 )   50 - 55   2014.2

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  • Gene expression profiling of sense and antisense transcripts in liver regeneration by microarray analysis.

    Mitsuru Chiba, Hiroshi Yasue, Nobuhiro Ohkohchi

    Biomedical Reports   1 ( 3 )   383 - 388   2013.5

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  • 4-Methylumbelliferone inhibits the phosphorylation of hyaluronan synthase 2 induced by 12-O-tetradecanoyl-phorbol-13-acetate.

    Yoshiyuki Kuroda, Kosuke Kasai, Naoki Nanashima, Hiroyuki Nozaka, Manabu Nakano, Mitsuru Chiba, Masahiko Yoneda, Toshiya Nakamura

    Biomedical Research   34 ( 2 )   97 - 103   2013.4

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  • Gene expression analyses of messenger RNA and non-coding RNA in X-ray irradiated human lymphoblastic cells.

    Mitsuru Chiba, Tomisato Miura, Kosuke Kasai, Satoru Monzen, Naoki Nanashima, Takashi Ishikawa, Teruko Takeo, Ikuo Kashiwakura, Toshiya Nakamura

    The 5th International Symposium on Radiation Emergency Medicine at Hirosaki University   5 ( 1 )   1 - 3   2013.3

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  • Effect of X-ray Irradiation on Extracellular Matrix Components of Rat Osteoblasts and Femurs

    Radiation emergency medicine   2 ( 1 )   43 - 49   2013.2

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  • Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.

    Bhavesh V Mistry, Yaqi Zhao, Ti-Cheng Chang, Hiroshi Yasue, Mitsuru Chiba, Jon Oatley, Francisco Diaz, Wan-Sheng Liu

    PLoS One   8 ( 4 )   e60611 - e60611   2013

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  • The synthesis of cytosolic ascorbate peroxidases in germinating seeds and seedlings of soybean and their behavior under flooding stress.

    Keito Nishizawa, Susumu Hiraga, Hiroshi Yasue, Mitsuru Chiba, Makoto Tougou, Yohei Nanjo, Setsuko Komatsu

    Bioscience, Biotechnology, Biochemistry   77 ( 11 )   2205 - 2209   2013

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  • Exosomes secreted from human colorectal cancer cell lines contain mRNAs, microRNAs and natural antisense RNAs, that can transfer into the human hepatoma HepG2 and lung cancer A549 cell lines.

    Mitsuru Chiba, Misako Kimura, Saya Asari

    Oncology Reports   28 ( 5 )   1551 - 1558   2012.11

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  • Radiation-responsive transcriptome analysis in human lymphoid cells.

    M Chiba

    Radiation protection dosimetry   152 ( 1-3 )   164 - 167   2012.11

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  • An efficient method for high-fidelity messenger RNA amplification from a small amount of total RNA.

    Mitsuru Chiba, Saya Asari, Misako Kimura, Toshiya Nakamura

    Biomedical Reports   1 ( 1 )   105 - 110   2012.10

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  • Differential expression profiles of sense and antisense transcripts between HCV-associated hepatocellular carcinoma and corresponding non-cancerous liver tissue.

    Kentaro Nagai, Keisuke Kohno, Mitsuru Chiba, Sugiru Pak, Soichiro Murata, Kiyoshi Fukunaga, Akihiko Kobayashi, Hiroshi Yasue, Nobuhiro Ohkohchi

    International journal of oncology   40 ( 6 )   1813 - 1820   2012.6

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  • Identification of up-regulated and down-regulated cis-natural antisense transcripts in the human B lymphoblastic cell line IM-9 after X-ray irradiation.

    Mitsuru Chiba, Tomisato Miura, Kosuke Kasai, Satoru Monzen, Ikuo Kashiwakura, Hiroshi Yasue, Toshiya Nakamura

    Molecular medicine reports   5 ( 5 )   1151 - 1157   2012.5

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  • Anti-inflammatory effect of proteoglycan and progesterone on human uterine cervical fibroblasts.

    Asami Fukuyama, Kanji Tanaka, Ikuko Kakizaki, Kosuke Kasai, Mitsuru Chiba, Toshiya Nakamura, Hideki Mizunuma

    Life sciences   90 ( 13-14 )   484 - 488   2012.4

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  • Characterization of a novel flooding stress-responsive alcohol dehydrogenase expressed in soybean roots.

    Setsuko Komatsu, Thibaut Deschamps, Deschamps Thibaut, Susumu Hiraga, Mikio Kato, Mitsuru Chiba, Akiko Hashiguchi, Makoto Tougou, Satoshi Shimamura, Hiroshi Yasue

    Plant molecular biology   77 ( 3 )   309 - 322   2011.10

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  • Elevation and characteristics of Rab30 and S100a8/S100a9 expression in an early phase of liver regeneration in the mouse.

    Mitsuru Chiba, Soichiro Murata, Andriy Myronovych, Keisuke Kohno, Noriko Hiraiwa, Masahide Nishibori, Hiroshi Yasue, Nobuhiro Ohkohchi

    International journal of molecular medicine   27 ( 4 )   567 - 574   2011.4

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  • Identification of natural antisense transcripts involved in human colorectal cancer development.

    Keisuke Kohno, Mitsuru Chiba, Soichiro Murata, Sugiru Pak, Kentaro Nagai, Masayoshi Yamamoto, Kazuhiko Yanagisawa, Akihiko Kobayashi, Hiroshi Yasue, Nobuhiro Ohkohchi

    International journal of oncology   37 ( 6 )   1425 - 1432   2010.12

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  • Existence of Pink1 antisense RNAs in mouse and their localization

    126 ( 3 )   2010.11

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  • Novel L-amino acid oxidase with antibacterial activity against methicillin-resistant Staphylococcus aureus isolated from epidermal mucus of the flounder Platichthys stellatus.

    Kosuke Kasai, Takashi Ishikawa, Takafumi Komata, Kaori Fukuchi, Mitsuru Chiba, Hiroyuki Nozaka, Toshiya Nakamura, Tatsusuke Sato, Tomisato Miura

    The FEBS journal   277 ( 2 )   453 - 465   2010.1

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  • alphaCGRP and betaCGRP transcript amount in mouse tissues of various developmental stages and their tissue expression sites.

    Abdol Hossein Rezaeian, Taeko Isokane, Masahide Nishibori, Mitsuru Chiba, Noriko Hiraiwa, Midori Yoshizawa, Hiroshi Yasue

    Brain & development   31 ( 9 )   682 - 693   2009.10

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  • Hepatoid carcinoma of the skin: spontaneous rat skin hepatoid carcinoma with eosinophilic globules and crystals immunoreactive to alpha-1-antitrypsin.

    Mihoko Sutoh, Mitsuru Chiba, Kosuke Kasai, Tomisato Miura, Hiroyuki Nozaka, Kiyotada Washiya, Etsuko Okusawa, Naoto Oyama, Chikako Tsutaya, Megumi Tsushima, Yuriko Terayama, Tomihisa Funyu, Tatsusuke Sato

    Medical molecular morphology   42 ( 2 )   118 - 122   2009.6

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  • Existence of Pink1 antisense RNAs in mouse and their localization.

    M Chiba, H Kiyosawa, N Hiraiwa, N Ohkohchi, H Yasue

    Cytogenetic and genome research   126 ( 3 )   259 - 270   2009

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  • Role of platelets on liver regeneration after 90% hepatectomy in mice.

    Andriy Myronovych, Soichiro Murata, Mitsuru Chiba, Ryota Matsuo, Osamu Ikeda, Motonobu Watanabe, Katsuji Hisakura, Yoritaka Nakano, Keisuke Kohno, Takuya Kawasaki, Ikuka Hashimoto, Yuki Shibasaki, Hiroshi Yasue, Nobuhiro Ohkohchi

    Journal of hepatology   49 ( 3 )   363 - 372   2008.9

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  • Apple procyanidins induce tumor cell apoptosis through mitochondrial pathway activation of caspase-3.

    Tomisato Miura, Mitsuru Chiba, Kosuke Kasai, Hiroyuki Nozaka, Toshiya Nakamura, Toshihiko Shoji, Tomomasa Kanda, Yasuyuki Ohtake, Tatsusuke Sato

    Carcinogenesis   29 ( 3 )   585 - 593   2008.3

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  • Localization of sense and antisense transcripts of Prdx2 gene in mouse tissues.

    M Chiba, M Kubo, T Miura, T Sato, A H Rezaeian, H Kiyosawa, N Ohkohchi, H Yasue

    Cytogenetic and genome research   121 ( 3-4 )   222 - 231   2008

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  • 相補性を有するPrdx2/JunBセンス/アンチセンス転写産物は独立して機能する

    千葉 満

    弘前大学大学院医学系研究科保健学専攻 修士論文   2007.3

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  • Ultraviolet light absorption of melanin through ultraviolet microscope analysis

    Muramatsu Atsushi, Kondo Jun, Suto Mihoko, Chiba Mitsuru, Nozaka Hiroyuki, Miura Tomisato, Takamatsu Terumasa, Sato Tatsusuke

    Bulletin of Health Sciences Hirosaki   6   141 - 150   2007

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  • リンゴポリフェノールはミトコンドリアを介して腫瘍細胞にアポトーシスを誘導する

    千葉 満

    弘前大学医学部保健学科検査技術科学専攻 卒業論文集   1   148 - 155   2005.3

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  • Simultaneous determination of haloperidol and bromperidol and their reduced metabolites by liquid-liquid extraction and automated column-switching high-performance liquid chromatography.

    Norio Yasui-Furukori, Yoshimasa Inoue, Misturu Chiba, Tomonori Tateishi

    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences   805 ( 1 )   175 - 180   2004.6

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  • プロシアニジンの抗腫瘍効果における重合度依存性

    千葉 満

    弘前大学医療技術短期大学部衛生技術学科 卒業特別研究論文集   25   176 - 183   2003.3

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Books

  • 大腸癌バイオマーカーとして有用なエキソソーム内在性アンチセンスRNAの同定.

    千葉満( Role: Sole author)

    公益財団法人鈴木謙三記念医科学応用研究財団研究報告.  2012.4 

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    Language:Japanese Book type:Report

  • 血清中エキソソーム内アンチセンスRNAによる新たな大腸癌スクリーニング法の開発.

    千葉満( Role: Sole author)

    科学研究費助成事業 若手研究(B)研究成果報告書. 課題番号23790613, 研究期間2011-2012年度  2013.4 

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    Language:Japanese Book type:Report

  • 体液中エキソソーム内在性RNAによる新たな迅速内部被ばく線量評価法の開発.

    千葉満( Role: Sole author)

    科学研究費助成事業 挑戦的萌芽研究 研究成果報告書. 課題番号25670264, 研究期間2013-2014年度  2015.3 

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  • 放射線被ばく線量評価に有用な血清・尿中エキソソーム内在性non-coding RNAバイオマーカーの同定.

    千葉満( Role: Sole author)

    公益財団法人 武田科学振興財団 2012年度 医学系研究奨励助成 研究成果報告書. 研究期間2013-2014年度  2015.3 

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    Language:Japanese Book type:Report

  • 弘前大学で見つけた 一〇七の言の葉ノート ―勉学・人生・世界観―

    千葉 満, 他( Role: Joint author)

    弘前大学出版会  2014.6 

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  • リンゴ果汁中ナノベシクル内microRNAによる大腸癌抑制効果の検討

    千葉 満( Role: Sole author)

    科学研究費助成事業 挑戦的萌芽研究 研究成果報告書. 課題番号15K12332, 研究期間2015-2017年度  2018.7 

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Review Papers

  • 尿比重 その測定原理, 臨床的意義を徹底解説

    千葉 満

    検査と技術   51 ( 11 )   1246 - 1250   2023.11

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  • Extracellular Vesiclesの細胞内取り込みメカニズム

    松本佳菜, 千葉満

    細胞   53 ( 10 )   650 - 653   2021.9

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  • 非アルコール性脂肪性肝炎における血清中マイクロRNAバイオマーカーの探索

    松本 佳菜, 千葉 満

    臨床病理   68 ( 補冊 )   231 - 231   2020.10

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  • 大腸がんの放射線治療時における照射線量制御バイオマーカーの探索

    門前 暁, 真里谷 靖, 千葉 満

    臨床病理   68 ( 補冊 )   186 - 186   2020.10

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  • 東北地区における臨床検査技師の人材確保と問題点 弘前大学における臨床検査技師育成と就職支援について

    千葉 満

    臨床病理   68 ( 補冊 )   083 - 083   2020.10

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  • 放射線被ばくした子ども期と大人期のマウスにおける血算成分と血清中microRNAの変化

    千葉 満, 松本 佳菜, 門前 暁, 真里谷 靖

    臨床病理   68 ( 補冊 )   230 - 230   2020.10

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  • 非アルコール性脂肪性肝炎の新規バイオマーカーとしての血清中マイクロRNAの探索

    松本 佳菜, 加藤 弓子, 林 百音, 大杉 悠平, 田山 千紗, 千葉 満

    医療検査と自動化   45 ( 4 )   448 - 448   2020.8

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  • 多層オミックス解析による認知症の早期発見のためのバイオマーカー探索

    多田羅 洋太, 中村 智洋, 山嵜 博未, 勝岡 史城, 千葉 満, 三枝 大輔, 葛西 秋宅, 伊東 健

    JSBMS Letters   45 ( Suppl. )   32 - 32   2020.8

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  • 青森県内に生息するマダニの病原体保有状況継続調査

    成田 美那, 吉岡 翔, 山口 平, 辻口 貴清, 千葉 満, 山内 可南子

    保健科学研究   10 ( 2 )   64 - 64   2020.3

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  • 地方における保健医療技術職へ外国人就労者が増大した際の医療環境変化の考察 多民族国家スウェーデンを参考に

    門前 暁, 森野 友貴, 千葉 満, Andrzej Wojcik

    保健科学研究   10 ( 2 )   35 - 40   2020.3

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  • 弘前大学検査技術科学専攻における過去11年の求人情報

    山内 可南子, 千葉 満, 吉岡 治彦, 武尾 照子, 渡邉 純, 丹藤 雄介, 伊藤 巧一

    臨床検査学教育   12 ( 1 )   1 - 6   2020.3

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    CiNii Books

  • 肝細胞癌体幹部定位放射線療法におけるradiation-induced liver disease

    真里谷靖, 門前暁, 千葉満

    臨床病理   68   2020

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    J-GLOBAL

  • 放射線抵抗性を示すHER2陽性乳癌患者の血清中Sphingomyelin関連代謝物の濃度変化の特徴

    門前 暁, 多田羅 洋太, 千葉 満, 真里谷 靖

    臨床病理   67 ( 補冊 )   167 - 167   2019.10

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  • バングラデシュにおける感染症を学ぶー教育・医療機関、環境調査を通してー

    山内 可南子,坂本 倭,吉岡 翔,千葉 満,藤岡 美幸

    第68回日本医学検査学会プログラム集   - 口頭発表(418)   2019.5

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  • バングラデシュにおける感染症を学ぶ 教育・医療機関、環境調査を通して

    山内 可南子, 坂本 倭, 吉岡 翔, 千葉 満, 藤岡 美幸

    日本医学検査学会抄録集   68回   418 - 418   2019.5

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  • 放射線技術学を用いた先端生命科学研究 放射線被ばく有害事象に対するバイオマーカの探索研究

    門前 暁, 上野 達也, 千葉 満, 真里谷 靖

    日本放射線技術学会雑誌   75 ( 5 )   480 - 485   2019.5

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  • HER-2陽性乳がんが放射線抵抗性を示す分子メカニズムの解明

    門前暁、多田羅洋太、千葉満

    平成30年度弘前大学異分野連携型若手研究支援事業・弘前大学グロウカル(Grow×Local)ファンド・弘前大学期間研究 研究成果集   - 口頭発表(5)   2019.3

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  • 学生市民等協働プログラム事業「バングラデシュにおける感染症ガバナンスー教育・医療機関、環境調査を通してー」

    山内可南子、坂本倭、吉岡翔、田澤一絋、吉田仁美、千葉満、藤岡美幸

    平成30年度グローカル人材育成事業概要   - 口頭発表(3)   2019.3

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  • 学生海外PBLプログラム事業「多様な民族が生活する環境下での地域保健医療者の育成」

    寺田賢司、森野友貴、山屋大樹、佐藤孝徳、千葉満、門前暁

    平成30年度グローカル人材育成事業 実績報告書   1 - 67   2019.3

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  • 学生市民等協働プログラム事業「バングラデシュにおける感染症ガバナンスー教育・医療機関、環境調査を通してー」

    山内可南子、坂本倭、吉岡翔、田澤一絋、吉田仁美、千葉満、藤岡美幸

    平成30年度グローカル人材育成事業 実績報告書   1 - 50   2019.3

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  • 学生海外PBLプログラム事業「多様な民族が生活する環境下での地域保健医療者の育成」

    寺田賢司、森野友貴、山屋大樹、佐藤孝徳、千葉満、門前暁

    平成30年度グローカル人材育成事業概要   - 口頭発表(9)   2019.3

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  • Malondialdehyde : A Urinary Toxic Biomarker for Unexpected Exposure to High-Dose Ionizing Radiation

    67 ( 3 )   212 - 215   2019.3

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    CiNii Books

  • 少数個転移性肝腫瘍に対する体幹部定位放射線療法に伴うradiation-induced liver diseaseの検討

    真里谷靖, 山田恭吾, 門前暁, 千葉満

    臨床病理   67   2019

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    J-GLOBAL

  • 非アルコール性脂肪性肝炎の新規バイオマーカーとしての血清中マイクロRNAの探索

    千葉 満, 門前 暁

    臨床病理, 第65回日本臨床検査医学会学術集会抄録集   66 ( Suppl. )   - 口頭発表(249)   2018.11

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  • 放射線被ばく時の急性骨髄障害における治療法の検討

    門前 暁、千葉 満、真里谷 靖

    臨床病理, 第65回日本臨床検査医学会学術集会抄録集   66 ( Suppl. )   - 口頭発表(139)   2018.11

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  • 非アルコール性脂肪性肝炎を発症した肝臓構成細胞における遺伝子発現の特徴

    加藤弓子、林百音、千葉満

    平成30年度日本臨床衛生検査技師会北日本支部医学検査学会(第7回)抄録集   - 口頭発表(66)   2018.11

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  • 非アルコール性脂肪性肝炎の新規バイオマーカーとしての血清中マイクロ RNA の探索

    林百音、加藤弓子、千葉満

    平成30年度日本臨床衛生検査技師会北日本支部医学検査学会(第7回)抄録集   - 口頭発表(67)   2018.11

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  • 尿中代謝産物を利用したバイオドシメトリ―の検討

    門前暁、寺田賢司、森野友貴、佐藤孝徳、千葉満

    日本放射線影響学会第61回大会抄録集   P2-24   2018.11

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  • 膵β細胞傷害はmiR-375-3pの細胞外への放出を増加させる

    千葉満、門前暁

    日本放射線影響学会第61回大会抄録集   P3-30   2018.11

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  • 高線量率被ばくマウスの骨髄中造血前駆細胞の損傷の特徴

    森野友貴、寺田賢司、佐藤孝徳、千葉満、WOJCIK Andrzej、門前暁

    日本放射線影響学会第61回大会抄録集   - 口頭発表(OA-4)   2018.11

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  • 去勢抵抗性前立腺癌骨転移患者に対するRa-223内照射の初期治療経験と予後不良例の 存在

    真里谷靖、吉川和暁、門前暁、千葉満

    日本放射線腫瘍学会第31回学術大会抄録集   - 口頭発表(O1-4)   2018.10

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  • 急性放射線障害に対する医療技術の検討 ~骨髄障害の重症化軽減を目指して~

    森野 友貴, 千葉 満, Andrzej Wojcik, 真里谷 靖, 門前 暁

    平成30年度放射線安全取扱部会年次大会抄録集   - ポスター発表(D-05)   2018.10

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  • ANTI-TUMOR AND ANTI-INVASION EFFECTS OF A COMBINATION OF 4-METHYLUMBELLIFERONE AND IONIZING RADIATION IN HUMAN FIBROSARCOMA CELLS

    Satoru Monzen, Mitsuru Chiba, Yoichiro Hosokawa

    The 33rd World Congress of the International Federation of Biomedical Laboratory Science (IFBLS2018) 抄録集   - PIN:158   2018.9

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  • EXOSOMES RELEASED FROM PANCREATIC CELLS ARE HETEROGENEOUS PARTICLE POPULATIONS

    Mitsuru Chiba, Satoru Monzen

    The 33rd World Congress of the International Federation of Biomedical Laboratory Science (IFBLS2018) 抄録集   - PIN:153   2018.9

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  • CHARACTERISTICS OF BONE MARROW SUBPOPULATION IN A MOUSE MODEL UNDER HIGH DOSE RATE IONIZING RADIATION EXPOSURE

    Yuki Morino, Satoru Monzen, Mitsuru Chiba, Misato Kamatsuka, Asami Fukui, Yasushi Mariya, Andrzej Wojcik

    The 33rd World Congress of the International Federation of Biomedical Laboratory Science (IFBLS2018) 抄録集   - PIN:157   2018.9

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  • URINARY BIOMARKERS OF LETHAL/SUBLETHAL IONIZING RADIATION DOSES

    Kenji Terada, Satoru Monzen, Mitsuru Chiba, Andrzej Wojcik, Yasushi Mariya

    The 33rd World Congress of the International Federation of Biomedical Laboratory Science (IFBLS2018) 抄録集   - PIN:208   2018.9

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  • EXOSOMES RELEASED FROM PANCREATIC CANCER CELLS INDUCE ACTIVATION AND ANGIOGENIC ACTIVITIES IN ENDOTHELIAL CELLS

    Mitsuru Chiba, Satoru Monzen

    The 33rd World Congress of the International Federation of Biomedical Laboratory Science (IFBLS2018) 抄録集   - PIN:152   2018.9

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  • SERUM MIR-375-3P INCREASE IN MICE EXPOSED TO A HIGH DOSE OF IONIZING RADIATION

    Mitsuru Chiba, Satoru Monzen

    The 33rd World Congress of the International Federation of Biomedical Laboratory Science (IFBLS2018) 抄録集   - PIN:188   2018.9

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  • A RADIORESISTANT FRACTION OF ACUTE PROMYELOCYTIC LEUKEMIA CELLS EXHIBIT CD38 CELL-SURFACE ANTIGEN AND MRNA EXPRESSION

    Satoru Monzen, Mitsuru Chiba, Yuki Morino, Kenji Terada, Hiroki Yamaya, Yoichiro Hosokawa

    The 33rd World Congress of the International Federation of Biomedical Laboratory Science (IFBLS2018) 抄録集   - PIN:189   2018.9

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  • SCREENING FOR BIOLOGICAL MARKER OF DOSE-OPTIMIZATION IN CANCER RADIOTHERAPY

    Satoru Monzen, Tatsuya Ueno, Mitsuru Chiba, Yoichiro Hosokawa

    The 33rd World Congress of the International Federation of Biomedical Laboratory Science (IFBLS2018) 抄録集   - PIN:196   2018.9

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  • EXOSOMES DERIVED FROM SW480 COLORECTAL CANCER CELLS PROMOTE CELL MIGRATION IN HEPG2 HEPATOCELLULAR CANCER CELLS VIA THE MITOGEN-ACTIVATED PROTEIN KINASE PATHWAY

    Mitsuru Chiba, Satoru Monzen

    The 33rd World Congress of the International Federation of Biomedical Laboratory Science (IFBLS2018) 抄録集   - PIN:150   2018.9

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  • EXOSOMES SECRETED FROM HUMAN COLORECTAL CANCER CELL LINES CONTAIN MRNAS, MICRORNAS AND NATURAL ANTISENSE RNAS, THAT CAN TRANSFER INTO THE HUMAN HEPATOMA HEPG2 AND LUNG CANCER A549 CELL LINES

    Mitsuru Chiba, Satoru Monzen

    The 33rd World Congress of the International Federation of Biomedical Laboratory Science (IFBLS2018) 抄録集   - PIN:151   2018.9

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  • 膵β細胞傷害は細胞外miR-375-3pを増加させる

    千葉 満

    第58回日本臨床化学会年次学術集会抄録集   P105   2018.8

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  • 放射線抵抗性を獲得させたHL-60細胞モデルの特徴とCD38発現との関連

    門前 暁,千葉 満

    第28回日本サイトメトリー学会学術集会抄録集   - ポスター(P-15)   2018.5

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  • 膵β細胞傷害は細胞外miR-375-3pを増加させる

    千葉 満,門前 暁

    第28回日本サイトメトリー学会学術集会抄録集   - ポスター(P-19)   2018.5

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  • 放射線被ばくマウスにおける造血細胞の変化と損傷

    森野友貴、千葉満、Wojcik Andrzej、門前暁

    第28回日本サイトメトリー学会学術集会抄録集   - ポスター発表(P-09)   2018.5

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  • The uptake mechanisms of extracellular vesicles into cells

    Mitsuru Chiba, Shiori Kubota, Satoru Monzen

    The Cell   50 ( 5 )   267 - 270   2018.4

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  • Investigation of Urinary Metabolic Molecules for Radiation Biodosimetry and Its Functional Analysis

    Kenji Terada,Yusuke Tawata,Mitsuru Chiba, Yasushi Mariya,Satoru Monzen

    第74回日本放射線技術学会総会学術大会抄録集   - 口頭発表(281)   2018.4

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  • 血液検体による放射線応答性マイクロRNAの探索

    千葉 満、門前 暁

    Cytometry Research   28 ( 1 )   1 - 6   2018.3

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  • 膵β細胞障害は細胞外miR-375-3pを増加させる

    新井山 育未,上原 悠花,桑田 遥,千葉 満

    Journal of Health Sciences Research   8 ( 2 )   2018.3

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  • 生物学的評価による放射線治療線量の最適化のための基礎的検討

    上野達也、門前暁、千葉満、細川洋一郎

    Cytometry Research   28 ( 1 )   7 - 11   2018.3

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  • 疾患バイオマーカーとしての体液中マイクロRNAの探索研究

    千葉 満

    臨床化学   47 ( 2 )   155 - 160   2018.3

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  • Serum microRNAs for early diagnosis of acute radiation syndrome

    - ポスター発表(2P-1115)   2017.12

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  • 尿中代謝物に着目した放射線被ばくの線量評価マーカーの探索

    門前 暁、寺田 賢司、多和田 侑介、真里谷 靖、千葉 満、Andrzej Wojcik

    2017年度生命科学系学会合同年次大会(ConBio2017)   - ポスター発表(1LBA-116)   2017.12

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  • 去勢抵抗性前立腺癌骨転移患者に対するRa-223内照射と腫瘍・骨代謝・酸化ストレスマーカーの経時的推移

    真里谷 靖、門前 暁、千葉 満

    第64回日本臨床検査医学会学術集会抄録集   - 口頭発表143   2017.11

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  • 尿中代謝産物をバイオマーカーとした放射線被ばく影響の評価

    門前 暁、千葉 満、真里谷 靖

    第64回日本臨床検査医学会学術集会抄録集   - 口頭発表185   2017.11

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  • 被ばくバイオマーカーとしての血中循環microRNAの検討

    千葉 満、門前 暁、真里谷 靖

    第64回日本臨床検査医学会学術集会抄録集   - 口頭発表141   2017.11

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  • A biomarker of acute radiation syndrome: miR-375-3p increases in mouse serum by exposure to lethal/sublethal dose

    Mitsuru Chiba, Satoru Monzen, Yasushi Mariya

    第29回世界病理臨床検査医学会連合会議(WASPaLM2017)   - Poster (P3-16)   2017.11

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  • Urinary biomarkers of lethal/sublethal ionizing radiation doses

    Satoru Monzen, Mitsuru Chiba, Yasushi Mariya

    第29回世界病理臨床検査医学会連合会議(WASPaLM2017)   2017.11

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  • Serum miR-375-3p as potential biomarkers of acute radiation syndrome in mice exposed to lethal dose

    千葉 満、門前 暁

    日本放射線影響学会第60回大会抄録集   - Poster (P-005)   2017.10

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  • 尿中代謝産物に着目した放射線被ばくマーカーの探索

    寺田 賢司、多和田 侑介、千葉 満、真里谷 靖、門前 暁

    日本放射線影響学会第60回大会抄録集   - 口頭発表(YA01-4)   2017.10

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  • 放射線治療の線量最適化のための細胞外microRNA発現の利用検討

    上野達也、門前 暁、千葉 満、細川洋一郎

    日本放射線影響学会第60回大会抄録集   - 口頭発表(YA05-3)   2017.10

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  • 子ども期の低線量放射線被ばくによる血中成分変化

    桑田 遥、上原 悠花、新井山 育未、千葉 満

    第6回日臨技北日本支部医学検査学会抄録集   - 口頭発表(演題114)   2017.10

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  • 膵β細胞障害は細胞外miR-375-3pを増加させる

    新井山 育未、上原 悠花、桑田 遥、千葉 満

    第6回日臨技北日本支部医学検査学会抄録集   - 口頭発表(演題112)   2017.10

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  • 急性被ばく腸管障害を予測できる血液・糞便中microRNAバイオマーカーの探索

    上原 悠花、桑田 遥、新井山 育未、千葉 満

    第6回日臨技北日本支部医学検査学会抄録集   - 口頭発表(演題110)   2017.10

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  • Serum miR-375-3p as potential biomarkers of acute radiation syndrome in mice exposed to lethal dose

    千葉 満

    第57回日本臨床化学会年次学術集会抄録集   - ポスター発表(P-100)   2017.10

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  • Serum miR-375-3p as potential biomarkers of acute radiation syndrome in mice exposed to lethal dose

    Mitsuru Chiba

    第76回日本癌学会学術総会抄録集   - Poster (P-3005)   2017.9

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  • Serum microRNAs for early diagnosis of acute radiation syndrome

    Mitsuru Chiba, Satoru Monzen, Chihiro Iwaya, Yuri Kashiwagi, Sunao Yamada, Yoichiro Hosokawa, Yasushi Mariya, Toshiya Nakamura, and Andrzej Wojcik

    4th Educational Symposium on RADIATION AND HEALTH by young scientists (ESRAH2017)   20 - Poster (P2)   2017.9

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  • Radiosensitivity regulation in fibrosarcoma cells by anti-inflammatory agents

    Ryo Saga, Kosho Murata, Mitsuru Chiba, Natsu Shibata, Toshiya Nakamura, Yoichiro Hosokawa

    4th Educational Symposium on RADIATION AND HEALTH by young scientists (ESRAH2017)   28 - Poster (P10)   2017.9

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  • Optimization of radiotherapy using extracellular microRNA expression

    Tatsuya Ueno, Satoru Monzen, Mitsuru Chiba, Yoichiro Hosokawa

    4th Educational Symposium on RADIATION AND HEALTH by young scientists (ESRAH2017)   26 - Poster (P8)   2017.9

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  • Investigation of urinary metabolic molecules for radiation biodosimetry

    Kenji Terada, Yusuke Tawada, Mitsuru Chiba, Yasushi Mariya, Satoru Monzen

    4th Educational Symposium on RADIATION AND HEALTH by young scientists (ESRAH2017)   21 - Poster (P3)   2017.9

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  • 放射線被ばくバイオマーカーとしての核酸代謝物の検討

    千葉 満

    日本臨床検査自動化学会第49回大会抄録集   2017.9

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  • 膵β細胞障害は細胞外miR-375-3pを増加させる

    新井山 育未、上原 悠花、桑田 遥、千葉 満

    第4回保健科学研究発表会   - 口頭発表(演題番号004)   2017.9

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  • Serum microRNAs for early diagnosis of acute radiation syndrome

    Mitsuru Chiba, Satoru Monzen

    第9回日本RNAi研究会・第4回日本細胞外小胞学会抄録集   - ポスター発表(P35)   2017.8

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  • 子ども期の低線量放射線被ばくによる血中成分変化

    桑田 遥、上原 悠花、新井山 育未、千葉 満

    第12回日本臨床検査学教育学会学術大会抄録集   9 ( Supp )   111 - 口頭発表105   2017.8

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  • 急性被ばく腸管障害を予測できる血液・糞便中microRNAバイオマーカーの探索

    上原 悠花、桑田 遥、新井山 育未、千葉 満

    第12回日本臨床検査学教育学会学術大会抄録集   9 ( Supp )   110 - 口頭発表104   2017.8

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  • がん細胞由来エキソソームの間質細胞への影響

    千葉満、門前暁

    細胞   49 ( 8 )   40 - 43   2017.8

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  • Serum miR-375-3p as potential biomarkers of acute radiation syndrome in mice exposed to lethal dose

    Mitsuru Chiba, Satoru Monzen, Chihiro Iwaya, Yuri Kashiwagi, Sunao Yamada, Yoichiro Hosokawa, Yasushi Mariya, Toshiya Nakamura, Andrzej Wojcik

    Chiang Mai – Hirosaki Joint Workshop on Health Sciences 2017   2017.7

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  • 放射線被ばくバイオマーカーとしての尿中8-OHdGの検討

    千葉満

    第66回日本医学検査学会 抄録集   2017.6

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  • 致死線量放射線被ばくバイオマーカーとしての血中循環microRNA

    千葉満、門前暁

    Cytometry Research(第27回日本サイトメトリー学会学術集会抄録集)   27 ( Suppl )   56   2017.6

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  • 放射線被ばく線量推定のための尿中バイオマーカーの探索

    門前暁、多和田侑介、千葉満、高坂望美、森野友貴、山屋大樹、上野達也、Andrzej Wojcik

    Cytometry Research(第27回日本サイトメトリー学会学術集会抄録集)   27 ( Suupl )   56   2017.6

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  • 生物学的評価による放射線治療線量の最適化のための基礎的検討

    上野達也、門前暁、千葉満、細川洋一郎

    Cytometry Research(第27回日本サイトメトリー学会学術集会抄録集)   27 ( Suppl )   57   2017.6

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  • Basic investigation to optimize radiation dose using biological information in radiotherapy

    203   2017.4

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  • ゲノム編集技術CRISPR/Cas9によるエキソソーム分泌関連遺伝子の探索

    千葉満

    平成28年度 弘前大学若手・新任研究者支援事業 成果発表会   2017.3

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  • 地域医療・ケア連携に基づく医療保健ネットワーク構築と生体ストレス低減プログラム

    【代表者】真里谷靖、【地域保健医療教育研究センター】丹藤雄介、渡邊純、井瀧千恵子、佐藤真由美、工藤幸清、北嶋結、【生体応答科学研究センター】中村敏也、細川洋一郎、三浦富智、七島直樹、千葉満、門前暁、山田正俊、吉田光明、床次眞司

    平成28年度 青森ブランド価値創造研究 成果発表会   2017.3

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  • 学生優秀発表賞:柏木悠里「急性放射線症候群バイオマーカーとしての血清中循環microRNA」

    柏木悠里、山田直、千葉満

    臨床検査学教育   9 ( 1 )   2017.3

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  • 学生優秀発表賞:山田直「細胞外へ分泌される膜小胞エキソソームは不均一な集団である」

    山田直、柏木悠里、千葉満

    臨床検査学教育   9 ( 1 )   2017.3

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  • Circulating microRNAs in blood for early diagnosis of acute radiation syndrome

    Mitsuru Chiba

    45 ( 補刷1 )   185 - 一般演題22(口頭発表)   2016.12

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  • 研究室紹介「大学院保健学研究科 放射線生体影響研究グループ」

    千葉満、門前暁、細川洋一郎

    学園だより   188   2016.12

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  • 放射線被ばくに対する生物学的線量評価の有効性の確認と新たな取組み

    門前暁, 千葉満, Lovisa Lundholm, Andrzej Wojcik

    平成28年度放射線安全取扱部会年次大会(第57回放射線管理研修会)   - ポスター発表(D-9)   2016.11

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  • 高線量放射線ばく露マウス血清中の microRNA 発現変化の被ばくマーカーと しての可能性の検討

    三浦 柊太、伊藤 優樹、山口 平、千葉 満、柏倉 幾郎

    日本放射線影響学会第59回大会   - P078(ポスター発表)   2016.10

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  • 致死線量放射線ばく露マウスに対するトロンボポエチン受容体作動薬の放射線緩和効果

    山口 平、廣内 篤久、横山 昂生、千葉 満、小村 潤一郎、柏倉 幾郎

    日本放射線影響学会第59回大会   - P076(ポスター発表)   2016.10

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  • ヒト白血病細胞における放射線抵抗性獲得後の細胞外小胞mRNA発現の特徴

    門前 暁、千葉 満、Andrzej Wojcik、真里谷 靖、細川 洋一郎

    日本放射線影響学会第59回大会   - P030(ポスター発表)   2016.10

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  • ヒト線維肉腫細胞に対する4-methylumbelliferone投与と放射線併用による放射線増感効果

    嵯峨 涼、門前 暁、千葉 満、上野 達也、村田 晃祥、中村 敏也、細川 洋一郎

    日本放射線影響学会第59回大会   - OA3-08(口頭発表)   2016.10

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  • Circulating microRNAs in serum for early diagnosis of acute radiation syndrome

    - OA1-09(口頭発表)   2016.10

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  • Radiation sensitizing effects of 4-methylumbelliferone targeting IL-6 signaling pathway

    R. Saga, S. Monzen, M. Chiba, T. Nakamura, T. Ueno, K. Murata, Y. Hosokawa

    40 - P14(ポスター発表)   2016.10

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  • The mitigative effects of romiplostim, a recombinant c-mpl agonist on the survival of mice exposed to lethal ionizing radiation

    M. Yamaguchi, K. Yokoyama, Y. Ito, S. Miura, M. Chiba, I. Kashiwakura

    The 3rd Educational Symposium on RADIATION AND HAELTH by Young Scientists (ESRAH2016)   28 - P2(ポスター発表)   2016.10

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  • 血清中循環microRNAに着目した新たな生物学的被ばく線量評価法の検討

    千葉満、門前暁、真里谷靖

    第63回日本臨床検査医学会学術集会プログラム集   86 - 17-2(口頭発表)   2016.9

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  • Predictive biomarkers for detecting adverse effects using radioisotope ablation in patients with papillary thyroid carcinoma

    Satoru Monzen, Mitsuru Chiba, Yoichiro Hosokawa, Yasushi Mariya

    IFBLS2016 Abstract Book (The 32nd World Congress of Biomedical Laboratory Science)   183 - PO-12(ポスター発表)   2016.9

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  • Serum microRNAs for early diagnosis of acute radiation syndrome

    Mitsuru Chiba, Satoru Monzen

    IFBLS2016 Abstract Book (The 32nd World Congress of Biomedical Laboratory Science)   161 - PL-03(ポスター発表)   2016.9

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  • 分化型甲状腺癌患者における放射性ヨウ素内用療法の効果及び有害事象を予測する因子の探索

    門前暁、千葉満、真里谷靖

    第63回日本臨床検査医学会学術集会プログラム集   86 - 16-3(ポスター発表)   2016.9

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  • 血清中循環microRNAに着目した新たな生物学的被ばく線量評価法の検討

    千葉満、門前暁、真里谷靖

    第63回日本臨床検査医学会学術集会プログラム集   86 - 17-2(ポスター発表)   2016.9

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  • 分化型甲状腺癌患者における放射性ヨウ素内用療法の効果及び有害事象を予測する因子の探索

    門前暁、千葉満、真里谷靖

    第63回日本臨床検査医学会学術集会プログラム集   86 - 16-3(口頭発表)   2016.9

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  • 急性放射線症候群バイオマーカーとしての血清中循環microRNA

    柏木悠里、山田直、千葉満

    臨床検査学教育「第11回日本臨床検査学教育学会学術大会抄録集」   8 ( 補刷 )   87 - 049(口頭発表)   2016.8

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  • 細胞外へ分泌される膜小胞エキソソームは不均一な集団である

    山田直、柏木悠里、千葉満

    臨床検査学教育「第11回日本臨床検査学教育学会学術大会抄録集」   8 ( 補刷 )   90 - 055(口頭発表)   2016.8

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  • 癌細胞由来エキソソームの間質細胞への影響

    千葉満、門前暁

    細胞   48 ( 9 )   30 - 33   2016.8

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  • 体液中エキソソームによる被ばく診断法

    千葉 満

    平成27年度 弘前大学若手・新任研究者支援事業 成果発表会   2016.3

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  • Report on the 2nd Educational Symposium on RADIATION AND HEALTH by Young Scientists (ESRAH2015)

    Tsujiguchi Takakiyo, Nanashima Naoki, Chiba Mitsuru, Terashima Shingo, Fujishima Yohei, Matsuya Yusuke, Kwon Jihun, Nakamura Toshiya

    Radiation Environment and Medicine   5 ( 1 )   65 - 71   2016.3

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  • 若手機関研究(平成25~27年度)「疾患エキソソームエンサイクロペディア~新規疾患マーカー探索戦略と総合的機能解析~」

    千葉 満

    平成27年度 弘前大学機関研究成果発表会   2016.2

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  • 急性放射線障害の予測バイオマーカーとして有用な血清中循環microRNAの探索

    千葉満, 岩谷千寿, 門前暁

    Biochemistry and Molecular Biology 2015 (BMB2015)   369 - 1P1334   2015.12

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  • Thrombopoietin-mimetic romiplostim confers the complete survival rate to mice exposed to lethal ionizing radiation

    Masaru Yamaguchi, Tokuhisa Hirouchi, Mitsuru Chiba, Satoru Monzen, Hironori Yoshino, Junya Ishikawa, Takakiyo Tsujiguchi, Ayaka Nishiyama, Sho Murakami, Junichiro Komura, Ikuo Kashiwakura

    Blood, 57th American Society of Hematology (ASH) Annual Meeting and Exposition   126 ( 23 )   2390   2015.12

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  • 甲状腺癌患者の血清代謝産物に着目した治療予後予測マーカーの探索

    門前暁, 新岡優, 高杉勇輝, Andrzej Wojcik, 千葉満, 高井良尋, 真里谷靖

    Biochemistry and Molecular Biology 2015 (BMB2015)   468 - 2P1226   2015.12

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  • 放射性ヨード内用療法施行甲状腺癌患者における身体影響評価法としての酸化ストレス関連マーカーの有用性

    真里谷靖, 門前暁, 對馬惠, 千葉満

    臨床病理, 第62回日本臨床検査医学会学術集会   63 ( 補冊 )   213 - O-247   2015.11

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  • 急性放射線障害の予測バイオマーカーとして有用な血清中microRNAの探索

    千葉満, 門前暁, 真里谷靖

    臨床病理, 第62回日本臨床検査医学会学術集会   63 ( 補刷 )   212 - O-246   2015.11

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  • 末梢血細胞を用いたCytokinesis-block micronucleus assayによる放射線医療被ばくの線量評価ツールの検討

    門前暁, 千葉満, 真里谷靖

    臨床病理, 第62回日本臨床検査医学会学術集会   63 ( 補刷 )   212 - O-245   2015.11

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  • Extracellular vesicles released from pancreatic cancer cells promote the vascularization of endothelial cells

    Mitsuru Chiba

    The 74th Annual Meeting of the Japanese Cancer Association   258 - P-3105   2015.10

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  • 血清エキソソームの回収法とmicroRNA解析法

    千葉満, 久保田栞, 門前暁, 丸山敦史

    検査と技術   43 ( 9 )   774 - 779   2015.9

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  • 放射線被ばくバイオマーカーとして有用な血清中microRNAの探索

    千葉満

    臨床検査学教育   7 ( 補冊 )   83 - 020   2015.8

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  • Extracellular vesicles released from pancreatic cancer cells promote cell migration and tube formation in endotherial cells

    Mitsuru Chiba, Shiori Kubota, Konomi Sato, Ayaka Sakai, Chihiro Kawamura, Satoru Monzen

    The 7th JARI & 2nd JSEV Annual Meeting   71 - PB-3   2015.8

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  • Predictive biomarker as acute radiation syndrome using serum microRNAs in mice exposed to sublethal dose of ionizing radiation

    Satoru Monzen, Mitsuru Chiba, Chihiro Iwaya, Toshiya Nakamura, Yasushi Mariya, Ikuo Kashiwakura

    The 7th JARI & 2nd JSEV Annual Meeting   61 - PA-11   2015.8

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  • Report on the 1st Educational Symposium on RADIATION AND HEALTH by Young Scientists (ESRAH2014)

    Toshiya Nakamura, Hironori Yoshino, Masaru Yamaguchi, Takakiyo Tsujiguchi, Mitsuru Chiba, Masahiro Hosoda

    4 ( 2 )   58 - 62   2015.8

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  • 4-メチルウンベリフェロンを併用したがん放射線療法の基礎的検討

    門前暁, 細川洋一郎, 嵯峨涼, 千葉満, 中村敏也, 真里谷靖

    Cytometry Research, 第25回日本サイトメトリー学会学術集会   25 ( 補冊 )   54 - O-24   2015.7

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  • Extracellular vesicles released from pancreatic cancer cells promote the vascularization of endothelial cells

    Mitsuru Chiba

    24th Annual Meeting of the Japanese Association for Metastasis Research   94 - P8-7   2015.7

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  • エキソソームはダイナミン依存的なエンドサイトーシス機構によって細胞内へ取り込まれる

    千葉満, 久保田栞, 門前暁

    Cytometry Research, 第25回日本サイトメトリー学会学術集会   25 ( 補冊 )   45 - O-5   2015.7

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  • 癌細胞から放出された分泌小胞エキソソームはレシピエント細胞の細胞遊走を亢進させる

    千葉満

    第1回細胞生物若手の会プログラム集   22   2015.6

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  • 分子細胞生物学講座 癌細胞由来エキソソームの癌微小環境における役割

    千葉 満, 門前 暁

    細胞   47 ( 6 )   302 - 305   2015.6

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  • 膵癌細胞から放出される細胞外小胞エキソソームは血管新生を亢進させる

    千葉満、久保田栞、佐藤このみ、酒井彩花、川村稚尋、門前暁

    The 67th Annual Meeting of the Japan Society for Cell Biology   195 - 2P-127   2015.6

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  • 膵癌細胞から放出される細胞外小胞エキソソームは血管新生を亢進させる

    千葉満、久保田栞、佐藤このみ、酒井彩花、川村稚尋、門前暁

    日本生化学会東北支部第81回例会・シンポジウム要旨集   83 - P-48   2015.5

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  • Effects of a c-Mpl agonist on mice exposed to lethal ionizing radiation

    Masaru Yamaguchi, Tokuhisa Hirouchi, Mitsuru Chiba, Satoru Monzen, Hironori Yoshino, Junya Ishikawa, Takakiyo Tsujiguchi, Ayaka Nishiyama, Sho Murakami, Jun-ichiro Komura, Ikuo Kashiwakura

    2nd Educational Symposium on Radiation and Health by young scientists (ESRAH2015)   P16   2015.5

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  • Effect of 4-methylumbelliferone and irradiation combination on factors related to a variety of invasion and metastasis

    Ryo Saga, Satoru Monzen, Hironori Yoshino, Mitsuru Chiba, Toshiya Nakamura, Yoichiro Hosokawa

    2nd Educational Symposium on Radiation and Health by young scientists (ESRAH2015)   P06   2015.5

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  • Serum microRNAs as potential biomarkers in mice exposed to ionizing radiation

    Mitsuru Chiba, Satoru Monzen, Ikuo Kashiwakura, Toshiya Nakamura

    2nd Educational Symposium on Radiation and Health by young scientists (ESRAH2015)   P04   2015.5

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  • Up-regulated and down-regulated cis-natural antisense transcripts in the human B lymphoblastic cells after X-ray irradiation

    Mitsuru Chiba, Satoru Monzen, Ikuo Kashiwakura, Toshiya Nakamura

    15th International Congress of Radiation Research (ICRR2015)   4-PS3G-07   2015.5

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  • Serum microRNAs as potential biomarkers in mice exposed to ionizing radiation

    Mitsuru Chiba, Satoru Monzen, Ikuo Kashiwakura, Toshiya Nakamura

    15th International Congress of Radiation Research (ICRR2015)   3-PS-LB-58   2015.5

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  • Effect of 4-methylumbelliferone and irradiation combination on factors related to a variety of invasion and metastasis

    Ryo Saga, Satoru Monzen, Hironori Yoshino, Mitsuru Chiba, Toshiya Nakamura, Yoichiro Hosokawa

    15th International Congress of Radiation Research (ICRR2015)   2-PS7N-01   2015.5

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  • Effects of a c-Mpl Agonist on Mice Exposed to Lethal Ionizing Radiation

    Masaru Yamaguchi, Tokuhisa Hirouchi, Mitsuru Chiba, Satoru Monzen, Hironori Yoshino, Junya Ishikawa, Takakiyo Tsujiguchi, Ayaka Nishiyama, Sho Murakami, Jun-ichiro Komura, Ikuo Kashiwakura

    15th International Congress of Radiation Research (ICRR2015)   3-PS5G-08   2015.5

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  • Effect of X-irradiation on the Components of Extracellular Matrix in Cultured Fetal Rat Osteoblasts and Rat Femora

    Toshiya Nakamura, Komei Tanaka, Mitsuru Chiba, Naoki Nanashima, Hiroyuki Nozaka, Takashi Ishikawa

    15th International Congress of Radiation Research (ICRR2015)   4-PS3H-13   2015.5

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  • 第2回若手研究者のための放射線と健康に関する教育シンポジウム(ESRAH2015)開催報告

    辻口 貴清, 山口 平, 七島 直樹, 千葉 満, 寺島 真悟, 藤嶋 洋平, 松谷 悠佑, 権 池勲, 中村 敏也

    日本放射線技術学会雑誌   71 ( 11 )   1132 - 1137   2015

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  • 第1回若手研究者のための放射線と健康に関する教育シンポジウム (ESRAH2014) の開催報告

    細田 正洋, 吉野 浩教, 山口 平, 辻口 貴清, 千葉 満, 中村 敏也

    保健物理   50 ( 1 )   20 - 24   2015

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  • RESEARCH HIGHLIGHTS 6, 疾患エキソソームエンサイクロペディア~新規疾患マーカー探索戦略と総合的機能解析~

    千葉 満

    2014 HIROSAKI UNIVERSITY RESEARCH HIGHLIGHTS   2015

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  • RESEARCH HIGHLIGHTS 6, Exosome research: Novel diagnostic and therapeutic tools for diseases

    Mitsuru Chiba

    2014 HIROSAKI UNIVERSITY RESEARCH HIGHLIGHTS   2015

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  • Inhibition of malignant tumor metastasis by 4-methylumbelliferone on X-irradiation

    Satoru Monzen, Yasushi Mariya, Andrzej Wojcik, Chika Kawamura, Ayumi Nakamura, Mitsuru Chiba, Yoshihiro Hosokawa, Yoshihiro Takai

    International Journal of Molecular Medicine   2014.10

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  • Acquisition of resistance to ionizing radiation in acute promyelocytic leukemia cells occurs via modifications of several mRNA expression networks

    Satoru Monzen, Ryo Saga, Mitsuru Chiba, Yoichiro Hosokawa

    International Journal of Molecular Medicine   2014.10

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  • Effects of a c-mpl receptor agonist on mice exposed to lethal ionizing radiation

    Masaru Yamaguchi, Tokuhisa Hirouchi, Mitsuru Chiba, Satoru Monzen, Hironori Yoshino, Junya Ishikawa, Takakiyo Tsujiguchi, Ayaka Nishiyama, Sho Murakami, Jun-ichiro Komura, Ikuo Kashiwakura

    The 9th International Symposium on the Natural Radiation Environment (NRE9)   2014.10

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  • 分化型甲状腺癌患者の放射性ヨウ素内用療法時に生じる末梢血応答機構の解明

    門前暁, 真里谷靖, Wojcik Andrzej, 川村千香, 中村歩美, 千葉満, 高井良尋

    第87回日本生化学会大会   2014.10

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  • 膵管癌微小環境における細胞外小胞エキソソームの役割

    千葉満, 酒井彩花, 久保田栞, 佐藤このみ, 川村稚尋, 門前暁, 七島直樹, 中村敏也

    第87回日本生化学会大会   2014.10

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  • I-131内服がん治療患者の生体内cytotoxic responseの評価

    門前暁, 真里谷靖, 千葉満, 細川洋一郎, 丸山敦史, 高井良尋

    日本放射線影響学会第57回大会   2014.10

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  • 膵管癌微小環境における細胞外小胞エキソソームの役割

    久保田栞, 千葉満, 酒井彩花, 川村稚尋, 佐藤このみ, 門前暁、七島直樹, 中村敏也

    第6回日本RNAi研究会/第1回日本細胞外小胞学会   2014.8

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  • 放射線抵抗性を獲得したヒト前骨髄性白血病細胞の情報伝達機構の特徴

    門前暁, 真里谷靖, 千葉満, 高井良尋

    第6回日本RNAi研究会/第1回日本細胞外小胞学会   2014.8

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  • 分化型甲状腺癌患者の131I 内用療法が末梢血液に与えるcytotoxic response の解析

    門前暁, 真里谷靖, 千葉満, 高井良尋

    日本放射線腫瘍学会第52回生物部会学術大会   2014.7

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  • 細胞外小胞エキソソームが介在する癌細胞間の細胞間コミュニケーション機構

    千葉満, 渡邊愛深, 渡邊美妃, 坂本茉生, 佐藤秋香, 藤崎瑞紀, 七島直樹, 中村敏也

    第66回日本細胞生物学会大会   2014.6

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  • Gene expression profiling of sense and antisense transcripts in liver regeneration by microarray analysis

    Mitsuru Chiba, Hiroshi Yasue, Nobuhiro Ohkohchi

    第61回日本実験動物学会総会   2014.5

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  • 肝臓癌細胞から放出される細胞外RNAの解析

    千葉 満

    第20回日本肝臓医生物学研究会(プロメテウスの会)   2014.2

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  • エキソソームが介在する消化器癌細胞の細胞間コミュニケーション

    千葉満, 渡邊愛深, 渡邊美妃, 坂本茉生, 佐藤秋香, 藤崎瑞紀, 浅利沙耶, 木村美紗子, 門前暁, 七島直樹, 金崎里香, 丸山敦史, 中村敏也

    第36回日本分子生物学会年会   2013.12

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  • Gene expression analyses of messenger RNA and non-coding RNA in human B lymphoblastic cells exposed to X-ray

    Chiba M, Miura T, Kasai K, Monzen S, Nanashima M, Ishikawa T, Takeo T, Kashiwakura I, Nakamura T

    The 5th International Symposium on Radiation Emergency Medicine in Hiroskai University   2013.10

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  • 致死線量放射線ばく露マウスに対するc-Mpl作動薬の作用

    石川純也, 廣内篤久, 伊藤巧一, 千葉 満, 中野 学, 門前 暁, 吉野浩教, 羽澤勝治, 中野 光, 山口 平, 田中公夫, 柏倉幾郎

    日本放射線影響学会第56回大会   2013.10

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  • 分泌小胞エキソソームに内在するRNAの種類と機能解析

    千葉満, 坂本茉生, 渡邊愛深, 渡邊美妃, 佐藤秋香, 藤崎瑞紀, 浅利沙耶, 木村美紗子, 中村敏也

    第86回日本生化学会大会   2013.9

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  • Radiation-responsive transcriptome analysis in human hematopoietic cells

    Mitsuru Chiba, Satoru Monzen, Kosuke Kasai, Tomisato Miura, Ikuo Kashiwakura, Toshiya Nakamura

    International Symposium on Natural Radiation Exposures and Low Dose Radiation Epidemiological Studies   2012.3

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  • 血液中センス/アンチセンスRNAを用いた大腸癌の新規診断法の開発

    高野 恵輔, 朴 秀吉, 永井 健太郎, 千葉 満, 村田 聡一郎, 久倉 勝治, 稲川 智, 安江 博, 大河内 信弘

    日本外科学会雑誌「第112回日本外科学会定期学術集会」   113 ( 2 )   SF-090-5   2012.3

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  • Radiation-responsive transcriptome analysis in human hematopoietic cells

    Mitsuru Chiba, Satoru Monzen, Kosuke Kasai, Tomisato Miura, Ikuo Kashiwakura, Toshiya Nakamura

    The 3rd International Symposium on Radiation Emergency Medicine at Hirosaki University   2011.9

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  • IN VITRO INFECTION AND REPLICATION OF HEPATITIS E VIRUS IN HUMAN HEPATOCYTES

    Y. Oshiro, H. Yasue, S. Hattori, M. Chiba, T. Naito, K. Takeuchi, K. Nagata, N. Ohkohchi

    Journal of Hepatology   54 ( Suppl. )   S535   2011.3

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  • NATURAL ANTISENSE TRANSCRIPTS ANALYSIS IS EFFECTIVE FOR DIAGNOSIS AND CARCINOGENESIS OF HEPATOCELLULAR CARCINOMA

    K. Nagai, S. Pak, K. Kohno, M. Chiba, S. Murata, H. Yasue, N. Ohkohchi

    Journal of Hepatology   54 ( Suppl. )   S394 - S395   2011.3

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  • 大腸癌の発癌・転移に関わるセンス/アンチセンスRNAの網羅的発現解析

    高野 恵輔, 千葉 満, 朴 秀吉, 永井 健太郎, 村田 聡一郎, 安江 博, 大河内 信弘

    日本外科学会雑誌「第110回日本外科学会定期学術集会」   111 ( 2 )   OP-059-2   2010.3

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  • カスタムマイクロアレイを用いた肝細胞癌における癌関連アンチセンスRNAの同定

    永井 健太郎, 高野 恵輔, 千葉 満, 朴 秀吉, 村田 聡一郎, 安江 博, 大河内 信弘

    日本外科学会雑誌「第110回日本外科学会定期学術集会」   111 ( 2 )   OP-059-6   2010.3

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  • 肝臓におけるナチュラル・アンチセンスRNAの網羅的遺伝子発現解析

    千葉満, 村田聡一郎, 永井健太郎, 高野恵輔, 朴秀吉, 安江博, 大河内信弘

    第5回広島肝臓プロジェクト研究センターシンポジウム   13   2009.7

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  • 肝再生に関与する新規遺伝子とアンチセンスRNAの網羅的解析

    千葉満, 村田聡一郎, ミロノビッチ・アンドリー, 高野恵輔, 朴秀吉, 安江博, 大河内信弘

    第45回日本肝臓学会総会   O-103   2009.6

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  • センス/アンチセンスカスタムマイクロアレイを用いた大腸癌における転写産物の解析

    高野 恵輔, 千葉 満, 朴 秀吉, 村田 総一郎, 鏡 良弘, 安江 博, 大河内 信弘

    日本外科学会雑誌「第109回日本外科学会定期学術集会」   110 ( 2 )   HP-033-3   2009.2

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  • 肝再生に関与する新規遺伝子とアンチセンスRNAの同定

    千葉満, 高野恵輔, 朴秀吉, アンドリー・ミロノビッチ, 村田聡一郎, 大河内信弘, 安江博

    第31回日本分子生物学会年会   1P-0891   2008.12

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  • ダイズにおける湿害応答因子アルコールデヒドロゲナーゼの発現解析

    橋口晶子, 千葉満, 加藤幹男, 湯川聖士, 島村聡, 山本亮, 中村卓司, 安江博, 小松節子

    第31回日本分子生物学会年会   4P-1248   2008.12

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  • ダイズにおける湿害応答因子アスコルビン酸ペルオキシダーゼの発現解析

    湯川聖士, 千葉満, 加藤幹男, 南條洋平, 島村聡, 山本亮, 中村卓司, 安江博, 小松節子

    第31回日本分子生物学会年会   3P-1267   2008.12

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  • センス/アンチセンスカスタムマイクロアレイを用いた大腸癌における転写産物の解析

    高野恵輔, 千葉満, 朴秀吉, 村田聡一郎, 安江博, 大河内信弘

    第31回日本分子生物学会年会   1P-0890   2008.12

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  • Transcript analysis on colorectal cancers using sense/antisense oligo microarray

    Keisuke Kohno, Mitsuru Chiba, Sugiru Pak, Soichiro Murata, Hidenori Kiyosawa Hiroshi Yasue, Nobuhiro Ohkohchi

    第67回日本癌学会年会   P-5093   2008.10

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  • Expression of HER-2/neu splice variants in the human breast cancer cells

    Chie Arai, Tomisato Miura, Kosuke Kasai, Mitsuru Chiba, Hiroyuki Nozaka, Rie Kazama, Atsushi Muramatsu, Tatsusuke Sato

    USCAP2008   2008.1

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  • cis-antisense RNAの検出と組織間における発現パターンの比較

    千葉満, 三浦富智, 佐藤達資, 安江博

    見てみて、聞いてみて、触ってみて弘前大学   P-23   2006.9

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  • Detection of sense and anti-sense transcripts from Ncam1 and Prdx2 genes in mouse tissues by in situ hybridization

    Mitsuru Chiba, Tomisato Miura, Tatsusuke Sato, Hiroshi Yasue

    30th International Conference on Animal Genetics   2006.8

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  • The analysis of apoptosis mechanism by the apple procyanidin in the mouse mammary tumor cells

    Tomisato Miura, Mitsuru Chiba, Kosuke Kasai, Hiroyuki Nozaka, Toshihiko Shoji, Tmomasa Kanda, Yasuyuki Ohtake, Tatsusuke Sato

    XXIIIth International Conference on Polyphenols   2006.8

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  • マウスの脳を含め各組織でのNcam1及びPrdx2センス/アンチセンス転写産物の発現部位の解析

    千葉満, 三浦富智, 清澤秀孔, 安江博

    第28回日本分子生物学会年会   2P-0725   2005.12

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  • リンゴプロシアニジンによるミトコンドリア障害とアポトーシスの誘導

    千葉満, 三浦富智, 葛西宏介, 佐藤達資, 庄司俊彦, 神田智正, 大竹康之

    第64回日本癌学会年会   PP1-0318   2005.9

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  • cRNAプローブを用いたin situ hybridization法の標準化

    千葉満, 三浦富智, 佐藤達資, 平岩秀樹, 安江博

    見てみて、聞いてみて、触ってみて弘前大学   P-35   2005.9

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  • 酵素処理米糠ヘミセルロースの免疫賦活活性

    三浦富智, 千葉満, 工藤潤, 加藤陽治

    見てみて、聞いてみて、触ってみて弘前大学   P-34   2005.9

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  • リンゴプロシアニジンによるアポトーシスの誘導

    三浦富智, 千葉満, 葛西宏介

    見てみて、聞いてみて、触ってみて弘前大学   P-33   2005.9

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  • リンゴポリフェノールの抗腫瘍活性に関する研究

    三浦富智, 千葉満, 佐藤達資, 庄司俊彦, 神田智正

    見てみて、聞いてみて、触ってみて弘前大学   P-54   2004.9

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  • リンゴポリフェノールにおけるアポトーシス誘導機序の解析

    千葉満, 三浦富智, 佐藤達資, 庄司俊彦, 神田智正

    第63回日本癌学会年会   P-1284   2004.9

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  • 米糠由来免疫調節物質の化学構造

    三浦富智, 千葉満, 加藤陽治

    第53回日本応用糖質科学会平成16年度大会   2004.9

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  • 腫瘍細胞に対するリンゴポリフェノールの細胞死誘導機序

    千葉満, 三浦富智, 佐藤達資, 庄司俊彦, 神田智正

    見てみて、聞いてみて、触ってみて弘前大学   P-55   2004.9

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  • Examination of the anti-tumor effect by the apple polyphenol and analysis of the anti-tumor coponent

    Tomisato Miura, Mitsuru Chiba, Hiroyuki Nozaka, Toshihiko Shoji, Tmomasa Kanda, Tatsusuke Sato

    XXⅡInternational congress on poly-phenols   2004.8

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  • The chemical structure of the component which is related to the immunomodulation

    Tomisato Miura, Mitsuru Chiba, Yuko Miyazaki, Yoji Kato, Hiroaki Maeda

    Presented at the 2004 General Meeting of the BioBran Study   2004.3

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Awards

  • 第18回インテリジェント・コスモス奨励賞(代表)

    2019.05

  • 平成30年度弘前大学学術特別賞 若手優秀論文賞(代表)

    2018.12

  • 日本臨床検査医学会 2017年度国際学会奨励賞(代表)

    2017.11

  • 平成29年度日本臨床化学会奨励賞(代表)

    2017.10

  • 平成28年度弘前大学学生表彰(指導教員、学生:柏木悠里)

    2017.03

  • 平成28年度弘前大学学生表彰(指導教員、学生:山田直)

    2017.03

  • 第56回日本臨床化学会年次学術集会 学術集会長賞(代表)

    2016.12

  • 第11回日本臨床検査学教育学会学術大会 優秀発表賞(分担、代表:山田直)

    2016.09

  • 第11回日本臨床検査学教育学会学術大会 優秀発表賞(分担、代表:柏木悠里)

    2016.09

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Social Activities

  • 全国 検査と健康展 in 秋田 進学相談

    2019.11

  • 大学進学説明会2015(東北七県新聞社主催)

    2015.06

  • 平成26年度校内進路ガイダンス(滝川高校主催)

    2014.11

  • 平成26年度弘前大学総合文化祭「知の創造」市民公開講座

    2014.10

  • 弘前大学オープンキャンパス

    2010.08

  • 全国 検査と健康展 in 秋田 進学相談

    2019.11

  • Editorial Board of Spandidos Publications (Experimental and Therapeutic Medicine)

    2019.06

  • 日本臨床検査学教育協議会 調査研究委員

    2019.06 - 2021.05

  • Editorial Board of Spandidos Publications (Molecular Medicine Reports)

    2019.04

  • 平成30年度日臨技北日本支部医学検査学会「学生フォーラム」準備委員

    2018.05 - 2018.11

  • 第12回日本臨床検査学教育学会 科目別分科会第5回例会(一般検査)

    2017.08

  • 八戸高校研究発表会

    2017.08

  • 平成29年度日臨技北日本支部医学検査学会「学生フォーラム」準備委員

    2017.05 - 2017.10

  • 第11回日本臨床検査学教育学会 科目別分科会第4回例会(一般検査)

    2016.09

  • 八戸高校研究発表会

    2016.08

  • 大学進学説明会2015(東北七県新聞社主催)

    2015.06

  • The 2nd Educational Symposium on Radiation and Health by Young Scientists (ESRAH2015) 準備委員

    2014.12 - 2015.05

  • 平成26年度校内進路ガイダンス(滝川高校主催)

    2014.11

  • 平成26年度弘前大学総合文化祭「知の創造」市民公開講座

    2014.10

  • 弘前大学同窓会理事

    2014.04

  • 弘前大学同窓会理事

    2014.04

  • 弘前大学同窓会報第15号編集委員

    2014.04 - 2015.03

  • The 9th International Symposium on the Natural Radiation Environment (NRE9)大会準備委員

    2013.12 - 2014.09

  • The 1st Educational Symposium on Radiation and Health by Young Scientists (ESRAH2014) 準備委員

    2013.12 - 2014.09

  • 弘前大学医学部保健学科さくら会副会長

    2013.04

  • 弘前大学医学部保健学科さくら会副会長

    2013.04

  • 生体応答科学研究センター市民講演会

    2012.11

  • 日本放射線影響学会第56回大会準備委員

    2012.10 - 2013.12

  • 生体応答科学研究センター市民講演会

    2011.01

  • 弘前大学オープンキャンパス

    2010.08

  • 産学官連携フェア「見てみて、聞いてみて、触ってみて、弘前大学」

    2004.09 - 2006.09

  • サイエンス・パートナーシップ・プログラム事業 教員研修「食中毒予防と細菌の遺伝子的鑑別」技術指導

    2003.12

  • サイエンス・パートナーシップ・プログラム事業 教員研修「食中毒予防と細菌の遺伝子的鑑別」技術指導

    2003.12

  • 子どもゆめ基金「高校生体験学習」技術指導

    2001.11 - 2003.08

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Media Coverage

  • 若手研究者11人表彰 インコス財団

    2019.05.22