Papers - YOSHINO HIRONORI
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Role of the Super-Enhancer Component Bromodomain Protein 4 in the Radiation Response of Human Head and Neck Squamous Cell Carcinoma Cells.
Munakata N, Yoshino H, Hazawa M, Tsuruga E
Current issues in molecular biology 48 ( 1 ) 2026.1
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Anticancer Effects of Combined Blue Light and Ionizing Irradiation.
Kitano K, Yoshino H, Kawanami K, Kajimoto R, Tsuruga E
Current issues in molecular biology 48 ( 1 ) 2025.12
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Impact of the ATM/Chk2 pathway and cell cycle phase on radiation-induced senescence in A549 human lung cancer cells.
Kota Sato, Hironori Yoshino, Yoshiaki Sato, Fuki Sasaki, Nanami Munakata, Eichi Tsuruga
Biomedical reports 23 ( 5 ) 169 - 169 2025.11
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Ionizing Radiation Combined with Gold Complex Compounds Causes Apoptosis in Colorectal Cancer Cells by Increasing the Level of Caspase-3.
Sano N, Yoshino H, Sato Y, Honma H, Cordonier CEJ, Kashiwakura I
Current molecular medicine 2025.1
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Involvement of cellular senescence in the effect of X-irradiated human lung fibroblast WI-38 cells on human lung cancer A549 cell clonogenic potential.
Hironori Yoshino, Katsuki Tadano, Chinatsu Omiya, Kae Ishii, Nanami Munakata
Radiation protection dosimetry 200 ( 16-18 ) 1608 - 1614 2024.11
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Radiation research trends by young scientists and the future tasks in Northern Japan: report on 'the 10th educational symposium on radiation and health (ESRAH) by young scientists in 2023'.
Ryosuke Seino, Hiroki Hashimoto, Haruka Kuwata, Worawat Poltabtim, Khemruthai Kheamsiri, Radhia Pradana, Saowarak Musikawan, Yuki Abe, Manaya Taoka, Rui Kudo, Chutima Kranrod, Hironori Yoshino, Masahiro Hosoda, Yusuke Matsuya
International journal of radiation biology 100 ( 12 ) 1731 - 1736 2024.10
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Phase-separated super-enhancers confer an innate radioresistance on genomic DNA.
Matsumoto K, Ikliptikawati DK, Makiyama K, Mochizuki K, Tobita M, Kobayashi I, Voon DC, Lim K, Ogawa K, Kashiwakura I, Suzuki HI, Yoshino H, Wong RW, Hazawa M
Journal of radiation research 2024.6
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Involvement of retinoic acid‑inducible gene‑I in radiation‑induced senescence of human umbilical vein endothelial cells
Fuki Sasaki, Hironori Yoshino, Ayumu Kusuhara, Kota Sato, Eichi Tsuruga
Biomedical Reports 20 ( 4 ) 2024.3
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Generality assessment of a model considering heterogeneous cancer cells for predicting tumor control probability for stereotactic body radiotherapy against non-small cell lung cancer
Ryo Saga, Yusuke Matsuya, Hideki Obara, Fumio Komai, Hironori Yoshino, Masahiko Aoki, Yoichiro Hosokawa
Advances in Radiation Oncology 101437 - 101437 2024.1
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Super-enhancer trapping by the nuclear pore via intrinsically disordered regions of proteins in squamous cell carcinoma cells.
Hazawa M, Ikliptikawati DK, Iwashima Y, Lin DC, Jiang Y, Qiu Y, Makiyama K, Matsumoto K, Kobayashi A, Nishide G, Keesiang L, Yoshino H, Minamoto T, Suzuki T, Kobayashi I, Meguro-Horike M, Jiang YY, Nishiuchi T, Konno H, Koeffler HP, Hosomichi K, Tajima A, Horike SI, Wong RW.
Cell Chemical Biology 2023.12
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Prediction of hub genes and key pathways associated with the radiation response of human hematopoietic stem/progenitor cells using integrated bioinformatics methods.
Sato Y, Yoshino H, Ishikawa J, Monzen S, Yamaguchi M, Kashiwakura I.
13 ( 1 ) 10762 2023.7
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ΔNp63 Regulates Radioresistance in Human Head and Neck Squamous Carcinoma Cells
Sato K, Yoshino H, Sato Y, Nakano M, Tsuruga E.
Current issues in molecular biology 45 ( 8 ) 6262 - 6271 2023.7
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DAP3-mediated cell cycle regulation and its association with radioresistance in human lung adenocarcinoma cell lines
Yoshiaki Sato, Hironori Yoshino, Kota Sato, Ikuo Kashiwakura, Eichi Tsuruga
2023.5
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Cytotoxic activity of unique synthesized five-membered heterocyclic compounds coordinated with tiopronin monovalent
Naoyuki Sanoa, Hironori Yoshinob, Yoshiaki Sato, Hideo Honma, Christopher E. J. Cordonierc, Ikuo Kashiwakura
2023.5
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Translational study for stereotactic body radiotherapy against non-small cell lung cancer, including oligometastases, considering cancer stem-like cells enable predicting clinical outcome from in vitro data
Ryo Saga, Yusuke Matsuya, Hikari Sato, Kazuki Hasegawa, Hideki Obara, Fumio Komai, Hironori Yoshino, Masahiko Aoki, Yoichiro Hosokawa
2023.4
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cGAS Regulates the Radioresistance of Human Head and Neck Squamous Cell Carcinoma Cells.
Taichi Nyui, Hironori Yoshino, Tetsuya Nunota, Yoshiaki Sato, Eichi Tsuruga
Cells 11 ( 9 ) 2022.4
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Effects and Related Mechanisms of the Senolytic Agent ABT-263 on the Survival of Irradiated A549 and Ca9-22 Cancer Cells.
Kota Sato, Soichiro Iwasaki, Hironori Yoshino
International journal of molecular sciences 22 ( 24 ) 2021.12
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The Effect of High-Dose-Rate Pulsed Radiation on the Survival of Clinically Relevant Radioresistant Cells.
Shingo Terashima, Hironori Yoshino, Yoshikazu Kuwahara, Hiro Sakuraba, Yoichiro Hosokawa
Life (Basel, Switzerland) 11 ( 12 ) 2021.11
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Discovery of a Novel Small-Molecule Interleukin-6 Inhibitor through Virtual Screening Using Artificial Intelligence.
Yoshiaki Sato, Ikuo Kashiwakura, Masaru Yamaguchi, Hironori Yoshino, Takeshi Tanaka, Ken Ikeda, Zhengmao Ye, Hirotsugu Komatsu, Takao Matsuzaki, Masato Hosoda
Medicinal chemistry (Shariqah (United Arab Emirates)) 2021.11
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Cytotoxic activity of a unique monomeric heterogeneous two-coordinate ligand monovalent gold complex with tiopronin and a heterocyclic mercapto-tetrazole compound.
Naoyuki Sano, Hironori Yoshino, Yoshiaki Sato, Hideo Honma, Christopher E J Cordonier, Ikuo Kashiwakura
Current medicinal chemistry 2021.10
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Not Only Hypoxia- but Radiation-Induced Epithelial-Mesenchymal Transition Is Modulated by Hypoxia-Inducible Factor 1 in A549 Lung Cancer Cells.
Sato M, Hirose K, Ichise K, Yoshino H, Harada T, Hatayama Y, Kawaguchi H, Tanaka M, Fujioka I, Takai Y, Aoki M
Folia biologica 67 ( 2 ) 62 - 69 2021.10
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KPNB1 Inhibitor Importazole Reduces Ionizing Radiation-Increased Cell Surface PD-L1 Expression by Modulating Expression and Nuclear Import of IRF1.
Hironori Yoshino, Yoshiaki Sato, Manabu Nakano
Current issues in molecular biology 43 ( 1 ) 153 - 162 2021.5
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Matrix Metalloproteinase-2 Activated by Ultraviolet-B Degrades Human Ciliary Zonules In Vitro
Yuki Shiroto, Ryo Saga, Hironori Yoshino, Yoichiro Hosokawa, Keitaro Isokawa, Eichi Tsuruga
Acta histochemica et cytochemica 54 ( 1 ) 1 - 9 2021.2
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DAP3 Is Involved in Modulation of Cellular Radiation Response by RIG-I-Like Receptor Agonist in Human Lung Adenocarcinoma Cells.
Yoshiaki Sato, Hironori Yoshino, Ikuo Kashiwakura, Eichi Tsuruga
International journal of molecular sciences 22 ( 1 ) 2021.1
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Karyopherin-β1 Regulates Radioresistance and Radiation-Increased Programmed Death-Ligand 1 Expression in Human Head and Neck Squamous Cell Carcinoma Cell Lines.
Masaharu Hazawa, Hironori Yoshino, Yuta Nakagawa, Reina Shimizume, Keisuke Nitta, Yoshiaki Sato, Mariko Sato, Richard W Wong, Ikuo Kashiwakura
Cancers 12 ( 4 ) 2020.4
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Disease-specific alteration of karyopherin-α subtype establishes feed-forward oncogenic signaling in head and neck squamous cell carcinoma.
Masaharu Hazawa, Kie Sakai, Akiko Kobayashi, Hironori Yoshino, Yoshihiro Iga, Yuki Iwashima, Kee Sing Lim, Dominic Chih-Cheng Voon, Yan-Yi Jiang, Shin-Ichi Horike, De-Chen Lin, Richard W Wong
Oncogene 39 ( 10 ) 2212 - 2223 2020.3
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GM管式サーベイメータのイメージと実用化に向けた工夫の検証
北宮千秋，吉野浩教，多喜代健吾，會津桂子，西沢義子，野戸結花，細川洋一郎
日本放射線看護学会誌 8 ( 1 ) 22 - 31 2020.3
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Fas Ligand Enhances Apoptosis of Human Lung Cancer Cells Cotreated with RIG-I-Like Receptor Agonist and Radiation.
Yoshiaki Sato, Hironori Yoshino, Eichi Tsuruga, Ikuo Kashiwakura
Current cancer drug targets 2020.1
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Cyclin A is a reliable proliferation marker in endometrial cancer cell lines.
Kayo Horie, Hayate Yamamoto, Kouhei Karube, Kai Takebayashi, Hironori Yoshino, Haruhiko Yoshioka, Jun Watanabe
Oncology letters 17 ( 5 ) 4455 - 4462 2019.5
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Effects of irradiated cell conditioned medium on the response of human lung cancer cells to anticancer treatment in vitro
Hironori Yoshino, Mikoto Nawamaki, Kanna Murakami, Ikuo Kashiwakura
World Academy of Sciences Journal 1 ( 2 ) 92 - 97 2019.4
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Dose-Dependent Increase of Nrf2 Target Gene Expression in Mice Exposed to Ionizing Radiation.
Shuta Miura, Masaru Yamaguchi, Hironori Yoshino, Yuji Nakai, Ikuo Kashiwakura
Radiation research 191 ( 2 ) 176 - 188 2019.2
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Involvement of caspase‑8 in apoptosis enhancement by cotreatment with retinoic acid‑inducible gene‑I‑like receptor agonist and ionizing radiation in human non‑small cell lung cancer.
Yoshiaki Sato, Hironori Yoshino, Yuka Kazama, Ikuo Kashiwakura
Molecular medicine reports 18 ( 6 ) 5286 - 5294 2018.12
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Relationship between the Regulation of Caspase-8-Mediated Apoptosis and Radioresistance in Human THP-1-Derived Macrophages.
Hironori Yoshino, Haruka Konno, Koya Ogura, Yoshiaki Sato, Ikuo Kashiwakura
International journal of molecular sciences 19 ( 10 ) 2018.10
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Effects of Nrf2 knockdown on the properties of irradiated cell conditioned medium from A549 human lung cancer cells.
Hironori Yoshino, Kanna Murakami, Mikoto Nawamaki, Ikuo Kashiwakura
Biomedical reports 8 ( 5 ) 461 - 465 2018.5
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Effects of retinoic acid-inducible gene-I-like receptors activations and ionizing radiation cotreatment on cytotoxicity against human non-small cell lung cancer in vitro.
Hironori Yoshino, Miyu Iwabuchi, Yuka Kazama, Maho Furukawa, Ikuo Kashiwakura
Oncology letters 15 ( 4 ) 4697 - 4705 2018.4
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Involvement of reactive oxygen species in ionizing radiation-induced upregulation of cell surface Toll-like receptor 2 and 4 expression in human monocytic cells.
Hironori Yoshino, Ikuo Kashiwakura
Journal of radiation research 58 ( 5 ) 626 - 635 2017.9
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Effects of endoplasmic reticulum stress on apoptosis induction in radioresistant macrophages.
Hironori Yoshino, Yu Kumai, Ikuo Kashiwakura
Molecular medicine reports 15 ( 5 ) 2867 - 2872 2017.5
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Anti-tumor and anti-invasion effects of a combination of 4-methylumbelliferone and ionizing radiation in human fibrosarcoma cells.
Ryo Saga, Satoru Monzen, Mitsuru Chiba, Hironori Yoshino, Toshiya Nakamura, Yoichiro Hosokawa
Oncology letters 13 ( 1 ) 410 - 416 2017.1
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p53-independent structure-activity relationships of 3-ring mesogenic compounds' activity as cytotoxic effects against human non-small cell lung cancer lines.
Saori Fukushi, Hironori Yoshino, Atsushi Yoshizawa, Ikuo Kashiwakura
BMC cancer 16 521 - 521 2016.7
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Effects of ionizing radiation on differentiation of murine bone marrow cells into mast cells.
Sho Murakami, Hironori Yoshino, Junya Ishikawa, Masaru Yamaguchi, Takakiyo Tsujiguchi, Ayaka Nishiyama, Kouki Yokoyama, Ikuo Kashiwakura
Journal of radiation research 56 ( 6 ) 865 - 871 2015.11
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Effects of X‑ray irradiation in combination with ascorbic acid on tumor control.
Yoichiro Hosokawa, Satoru Monzen, Hironori Yoshino, Shingo Terashima, Manabu Nakano, Keisuke Toshima, Ryo Saga, Ikuo Kashiwakura
Molecular medicine reports 12 ( 4 ) 5449 - 5454 2015.10
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Effects of ionizing radiation on retinoic acid-inducible gene-I-like receptors.
Hironori Yoshino, Takahiro Saitoh, Masataka Kozakai, Ikuo Kashiwakura
Biomedical reports 3 ( 1 ) 59 - 62 2015.1
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Mitigative Effects of a Combination of Multiple Pharmaceutical Drugs on the Survival of Mice Exposed to Lethal Ionizing Radiation.
Tokuhisa Hirouchi, Koichi Ito, Manabu Nakano, Satoru Monzen, Hironori Yoshino, Mitsuru Chiba, Masaharu Hazawa, Akira Nakano, Junya Ishikawa, Masaru Yamaguchi, Kimio Tanaka, Ikuo Kashiwakura
Current pharmaceutical biotechnology 17 ( 2 ) 190 - 199 2015
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Effects of liquid crystallinity on anticancer activity of benzoate derivatives possessing a terminal hydroxyl group.
2. Fukushi Y, Yoshino H, Ishikawa J, Sagisaka M, Yoshizawa A, Kashiwakura I.
Liquid Crystals 41 ( 12 ) 1873 - 1878 2014.11
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Ionizing radiation affects the expression of Toll-like receptors 2 and 4 in human monocytic cells through c-Jun N-terminal kinase activation.
Hironori Yoshino, Kanae Chiba, Takahiro Saitoh, Ikuo Kashiwakura
Journal of radiation research 2014.6
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Long-lasting Radioprotective Effects of a Combination of Pharmaceutical Drugs on the Survival of Mice Exposed to Lethal Ionizing Radiation.（共著）
Yamaguchi M, Hirouchi T, Nakano M, Monzen S, Yoshino H, Chiba M, Ishikawa J, Nishiyama A, Murakami S, Ito K, Kashiwakura I.
Radiation Emergency Medicine 3 ( 1 ) 50 - 55 2014.2
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Effect of ascorbic acid and X-irradiation on HL-60 human leukemia cells: the kinetics of reactive oxygen species.
Shingo Terashima, Yoichiro Hosokawa, Hironori Yoshino, Masaru Yamaguchi, Toshiya Nakamura
Oncology reports 30 ( 6 ) 2653 - 2658 2013.12
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Synthesis and anticancer properties of phenyl benzoate derivatives possessing a terminal hydroxyl group.（共著）
Fukushi Y, Yoshino H, Ishikawa J, Sagisaka M, Kashiwakura I, Yoshizawa A.
Journal of Materials Chemistry B 2 1335 - 1343 2013.12
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Mitochondrial Superoxide Production and Redox Status in Human Monocytic Cells after Ionizing Irradiation.（共著）
Yoshino H, Kiminarita T, Matsushita Y, Kashiwakura I.
Radiation Emergency Medicine 2 ( 2 ) 43 - 48 2013.9
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An Investigation of Gamma-ray Dose Rate in the Central Area of Hirosaki City, Japan.（共著）
Yoshino H, Obara H, Maeda T, Yamada A, Watanabe K, Hosoda M, Sorimachi A, Ishikawa T, Tokonami S.
Radiation Emergency Medicine 2 ( 2 ) 72 - 76 2013.9
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Effects of radiation on the maturation of megakaryocytes.
Katsumi Hirose, Satoru Monzen, Hironori Yoshino, Haruka Sato, Masahiko Aoki, Yoshiomi Hatayama, Hideo Kawaguchi, Mariko Sato, Yuichiro Narita, Yoshihiro Takai, Ikuo Kashiwakura
Journal of radiation research 54 ( 3 ) 447 - 452 2013.5
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A liquid crystal-related compound induces cell cycle arrest at the G2/M phase and apoptosis in the A549 human non-small cell lung cancer cell line.
Takuya Wakasaya, Hironori Yoshino, Yukako Fukushi, Atsushi Yoshizawa, Ikuo Kashiwakura
International journal of oncology 42 ( 4 ) 1205 - 1211 2013.4
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Characteristics of myeloid differentiation and maturation pathway derived from human hematopoietic stem cells exposed to different linear energy transfer radiation types.
Satoru Monzen, Hironori Yoshino, Kiyomi Kasai-Eguchi, Ikuo Kashiwakura
PloS one 8 ( 3 ) e59385 - e59385 2013
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Activity concentrations of environmental samples collected in Fukushima Prefecture immediately after the Fukushima nuclear accident.
Masahiro Hosoda, Shinji Tokonami, Hirofumi Tazoe, Atsuyuki Sorimachi, Satoru Monzen, Minoru Osanai, Naofumi Akata, Hideki Kakiuchi, Yasutaka Omori, Tetsuo Ishikawa, Sarata K Sahoo, Tibor Kovács, Masatoshi Yamada, Akifumi Nakata, Mitsuaki Yoshida, Hironori Yoshino, Yasushi Mariya, Ikuo Kashiwakura
Scientific reports 3 2283 - 2283 2013
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Response of the Nrf2 protection system in human monocytic cells after ionising irradiation.
H Yoshino, T Kiminarita, Y Matsushita, I Kashiwakura
Radiation protection dosimetry 152 ( 1-3 ) 104 - 108 2012.11
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Impairment of mature dendritic cells derived from X-irradiated human monocytes depends on the type of maturation stimulus used.
Hironori Yoshino, Ikuo Kashiwakura
Radiation research 178 ( 4 ) 280 - 288 2012.10
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Regulation of DNA damage response and cell cycle in radiation-resistant HL60 myeloid leukemia cells.
Masaharu Hazawa, Yoichiro Hosokawa, Satoru Monzen, Hironori Yoshino, Ikuo Kashiwakura
Oncology reports 28 ( 1 ) 55 - 61 2012.7
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アンケート調査による放射線技術科学専攻学生の臨床実習に対する意識調査報告
2. 對馬 惠，齋藤陽子，西澤一治，細川洋一郎，石戸俊雄，小山内 暢，門前 暁，寺島真悟，吉野浩教
保健科学研究 2 ( 2 ) 155 - 160 2012.3
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Involvement of intracellular reactive oxygen species and mitochondria in the radiosensitivity of human hematopoietic stem cells.
Yukiko Kaneyuki, Hironori Yoshino, Ikuo Kashiwakura
Journal of radiation research 53 ( 1 ) 145 - 150 2012
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The potential of patients' peripheral blood mononuclear cells to differentiate into dendritic cells after hematopoietic stem cell transplantation.
Hironori Yoshino, Naoki Watanabe, Kenji Takahashi, Kazuto Ogura, Tomoaki Akagi, Kohmei Kubo, Ikuo Kashiwakura
Life sciences 89 ( 25-26 ) 946 - 955 2011.12
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Terminal maturation of megakaryocytes and platelet production by hematopoietic stem cells irradiated with heavy-ion beams.
Monzen S, Takahashi K, Yoshino H, Kasai-Eguchi K, Kashiwakura I.
Radiation Research 176 ( 1 ) 8 - 16 2011.7
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Individual radiation exposure dose due to support activities at safe shelters in Fukushima Prefecture.
Satoru Monzen, Masahiro Hosoda, Shinji Tokonami, Minoru Osanai, Hironori Yoshino, Yoichiro Hosokawa, Mitsuaki A Yoshida, Masatoshi Yamada, Yasushi Asari, Kei Satoh, Ikuo Kashiwakura
PloS one 6 ( 11 ) e27761 - e27761 2011
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Effects of proteoglycan extracted from nasal cartilage of salmon heads on maturation of dendritic cells derived from human peripheral blood monocytes.
Hironori Yoshino, Kenji Takahashi, Satoru Monzen, Ikuo Kashiwakura
Biological & pharmaceutical bulletin 33 ( 2 ) 311 - 315 2010
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Proteoglycans regulate the chemotaxis of dendritic cells derived from human peripheral blood monocytes.
Hironori Yoshino, Kenji Takahashi, Satoru Monzen, Ikuo Kashiwakura
Biological & pharmaceutical bulletin 33 ( 6 ) 938 - 944 2010
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Inductive potential of recombinant human granulocyte colony-stimulating factor to mature neutrophils from x-irradiated human peripheral blood hematopoietic progenitor cells.
Takeo Katsumori, Hironori Yoshino, Masako Hayashi, Kenji Takahashi, Ikuo Kashiwakura
Biological & pharmaceutical bulletin 32 ( 11 ) 1849 - 1853 2009.11
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Heavy ion beam irradiation regulates the mRNA expression in megakaryocytopoiesis from human hematopoietic stem/progenitor cells.
Satoru Monzen, Kenji Takahashi, Hironori Yoshino, Kiyomi Kasai-Eguchi, Yoshinao Abe, Atsushi Maruyama, Ken Itoh, Ikuo Kashiwakura
Journal of radiation research 50 ( 5 ) 477 - 486 2009.9
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Effects of a 2-step culture with cytokine combinations on megakaryocytopoiesis and thrombopoiesis from carbon-ion beam-irradiated human hematopoietic stem/progenitor cells.
Kenji Takahashi, Satoru Monzen, Hironori Yoshino, Yoshinao Abe, Kiyomi Eguchi-Kasai, Ikuo Kashiwakura
Journal of radiation research 49 ( 4 ) 417 - 424 2008.7
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Differential induction from X-irradiated human peripheral blood monocytes to dendritic cells.
Hironori Yoshino, Kenji Takahashi, Satoru Monzen, Ikuo Kashiwakura
Journal of radiation research 49 ( 3 ) 293 - 303 2008.5