Affiliation
University Hospital Pediatrics
SATO TOMOHIKO
Degree
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博士（医学）
Education
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Hirosaki University 医学研究科
2004.04 ～ 2008.03
Country： Japan
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Hirosaki University 医学部 医学科
1996.04 ～ 2002.03
Country： Japan
Campus Career
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Hirosaki University University Hospital Pediatrics Assistant Professor
2016.01 ～ Now
Research History
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Kyoto University Researcher
2015.04 ～ 2015.10
Research Interests
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myeloid leukemia-associated with Down syndrome (ML-DS)
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Transient abnormal myelopoiesis (TAM)
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Diamond-Blackfan anemia
Papers
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Landscape of driver mutations and their clinical effects on Down syndrome-related myeloid neoplasms.
Sato T, Yoshida K, Toki T, Kanezaki R, Terui K, Saiki R, Ojima M, Ochi Y, Mizuno S, Yoshihara M, Uechi T, Kenmochi N, Tanaka S, Matsubayashi J, Kisai K, Kudo K, Yuzawa K, Takahashi Y, Tanaka T, Yamamoto Y, Kobayashi A, Kamio T, Sasaki S, Shiraishi Y, Chiba K, Tanaka H, Muramatsu H, Hama A, Hasegawa D, Sato A, Koh K, Karakawa S, Kobayashi M, Hara J, Taneyama Y, Imai C, Hasegawa D, Fujita N, Yoshitomi M, Iwamoto S, Yamato G, Saida S, Kiyokawa N, Deguchi T, Ito M, Matsuo H, Adachi S, Hayashi Y, Taga T, Saito AM, Horibe K, Watanabe K, Tomizawa D, Miyano S, Takahashi S, Ogawa S, Ito E
143 ( 25 ) 2627 - 2643 2024.6
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De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome
Toki T, Yoshida K, Wang R, Nakamura S, Maekawa T, Goi K, Katoh MC, Mizuno S, Sugiyama F, Kanezaki R, Uechi T, Nakajima Y, Sato Y, Okuno Y, Sato-Otsubo A, Shiozawa Y, Kataoka K, Shiraishi Y, Sanada M, Chiba K, Tanaka H, Terui K, Sato T, Kamio T, Sakaguchi H, Ohga S, Kuramitsu M, Hamaguchi I, Ohara A, Kanno H, Miyano S, Kojima S, Ishiguro A, Sugita K, Kenmochi N, Takahashi S, Eto K, Ogawa S, Ito E
American Journal of Human Genetics 2018.9
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Antileukemic effect of azacitidine, a DNA methyltransferase inhibitor, on cell lines of myeloid leukemia associated with Down syndrome.
Tanaka T, Kudo K, Kanezaki R, Yuzawa K, Toki T, Okuse R, Kobayashi A, Sato T, Kamio T, Terui K, Ito E
Experimental hematology 132 104179 2024.4
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Early-onset Marfan syndrome with a novel missense mutation: A case report.
Soma K, Kitagawa Y, Toki T, Miura F, Shimada J, Sato T, Kudo K, Otani K, Takahashi T, Terui K
27 ( 6 ) 283 - 286 2023.6
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Mechanism of KIT gene regulation by GATA1 lacking the N-terminal domain in Down syndrome-related myeloid disorders.
Kanezaki R, Toki T, Terui K, Sato T, Kobayashi A, Kudo K, Kamio T, Sasaki S, Kawaguchi K, Watanabe K, Ito E
12 ( 1 ) 20587 2022.11
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BRAF V600E-positive cells as molecular markers of bone marrow disease in pediatric Langerhans cell histiocytosis.
Kudo K, Toki T, Kanezaki R, Tanaka T, Kamio T, Sato T, Sasaki S, Imamura M, Imai C, Ando K, Kakuda H, Doi T, Kawaguchi H, Irie M, Sasahara Y, Tamura A, Hasegawa D, Itakura Y, Watanabe K, Sakamoto K, Shioda Y, Kato M, Kudo K, Fukano R, Sato A, Yagasaki H, Kanegane H, Kato I, Umeda K, Adachi S, Kataoka T, Kurose A, Nakazawa A, Terui K, Ito E
107 ( 7 ) 1719 - 1725 2022.7
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Childhood acute myeloid leukemia with 5q deletion and HNRNPH1-MLLT10 fusion: the first case report.
Kudo K, Kubota Y, Toki T, Kanezaki R, Kobayashi A, Sato T, Kamio T, Sasaki S, Shiba N, Tomizawa D, Adachi S, Yoshida K, Ogawa S, Seki M, Takita J, Ito E, Terui K
6 ( 10 ) 3162 - 3166 2022.5
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Isolated Bone Recurrence of Medulloblastoma With MYCN Amplification and TP53 Loss: A Case Report.
Takahashi Y, Kudo K, Ogawa K, Sato T, Kamio T, Sasaki S, Kobayashi A, Ito T, Yamamoto T, Asano K, Ohkuma H, Kurose A, Ito E, Terui K
Journal of pediatric hematology/oncology 44 ( 2 ) e593 - e596 2022.3
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Erythromelalgia presenting as recurrent purpura and hypogammaglobulinemia: A case report
Karasawa Takao, Hashimoto Shun, Sato Riko, Fujita Masashi, Aizawa Tomomi, Tsugawa Koji, Toki Tsutomu, Kanezaki Rika, Sato Tomohiko, Kudo Ko, Terui Kiminori, Tanaka Hiroshi
Hirosaki Medical Journal 72 ( 1-4 ) 80 - 83 2022
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Association of Multiple Gene Polymorphisms Including Homozygous NUDT15 R139C With Thiopurine Intolerance During the Treatment of Acute Lymphoblastic Leukemia.
Kudo K, Sato T, Takahashi Y, Yuzawa K, Kobayashi A, Kamio T, Sasaki S, Shimada J, Otani K, Tusjimoto S, Kato M, Toki T, Terui K, Ito E
Journal of pediatric hematology/oncology 43 ( 8 ) e1173 - e1176 2021.11
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Correction: Reduced-intensity conditioning is effective for hematopoietic stem cell transplantation in young pediatric patients with Diamond-Blackfan anemia.
Koyamaishi S, Kamio T, Kobayashi A, Sato T, Kudo K, Sasaki S, Kanezaki R, Hasegawa D, Muramatsu H, Takahashi Y, Sasahara Y, Hiramatsu H, Kakuda H, Tanaka M, Ishimura M, Nishi M, Ishiguro A, Yabe H, Sarashina T, Yamamoto M, Yuza Y, Hyakuna N, Yoshida K, Kanno H, Ohga S, Ohara A, Kojima S, Miyano S, Ogawa S, Toki T, Terui K, Ito E
Bone marrow transplantation 56 ( 5 ) 1218 - 1219 2021.5
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A Rapid Cytologic Double Staining of Epstein-Barr Virus-encoded Small RNA and Cell Surface Markers for Diagnosis of Epstein-Barr Virus-associated Hemophagocytic Lymphohistiocytosis
Natsuki Takahashi, Ko Kudo, Miyuki Tanaka, Naoya Kumagai, Tomohiko Sato, Takuya Kamio, Shinya Sasaki, Kiminori Terui, Akira Kurose, Ryu Yanagisawa, Yozo Nakazawa, Etsuro Ito
Journal of Pediatric Hematology/Oncology 2020.11
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Reduced-intensity conditioning is effective for hematopoietic stem cell transplantation in young pediatric patients with Diamond-Blackfan anemia
Shun Koyamaishi, Takuya Kamio, Akie Kobayashi, Tomohiko Sato, Ko Kudo, Shinya Sasaki, Rika Kanezaki, Diichiro Hasegawa, Hideki Muramatsu, Yoshiyuki Takahashi, Yoji Sasahara, Hidefumi Hiramatsu, Harumi Kakuda, Miyuki Tanaka, Masataka Ishimura, Masanori Nishi, Akira Ishiguro, Hiromasa Yabe, Takeo Sarashina, Masaki Yamamoto, Yuki Yuza, Nobuyuki Hyakuna, Kenichi Yoshida, Hitoshi Kanno, Shouichi Ohga, Akira Ohara, Seiji Kojima, Satoru Miyano, Seishi Ogawa, Tsutomu Toki, Kiminori Terui, Etsuro Ito
Bone Marrow Transplantation 2020.9
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Clinical, cytogenetic, and molecular analyses of 17 neonates with transient abnormal myelopoiesis and nonconstitutional trisomy 21.
Yuzawa K, Terui K, Toki T, Kanezaki R, Kobayashi A, Sato T, Kamio T, Kudo K, Sasaki S, Endo M, Ozono S, Nomura K, Ito E
Pediatric blood & cancer 67 ( 4 ) e28188 2020.4
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MYH7 mutation identified by next-generation sequencing in three infant siblings with bi-ventricular noncompaction presenting with restrictive hemodynamics: A report of three siblings with a severe phenotype and poor prognosis.
Miura F, Shimada J, Kitagawa Y, Otani K, Sato T, Toki T, Takahashi T, Yonesaka S, Mizukami H, Ito E
Journal of cardiology cases 19 ( 4 ) 140 - 143 2019.4
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Comprehensive genetic analyses of relapsed B-cell precursor acute lymphoblastic leukemia in children
Kubo Kaori, Kudo Ko, Toki Tsutomu, Kanezaki Rika, Ikeda Fumika, Ito Tatsuya, Kobayashi Akie, Sato Tomohiko, Kamio Takuya, Sasaki Shinya, Terui Kiminori, Ito Etsuro
Hirosaki Medical Journal 70 ( 1 ) 13 - 23 2019
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Two siblings with familial neuroblastoma with distinct clinical phenotypes harboring an ALK germline mutation
Kudo K, Ueno H, Sato T, Kubo K, Kanezaki R, Kobayashi A, Kamio T, Sasaki S, Terui K, Kurose A, Yoshida K, Shiozawa Y, Toki T, Ogawa S, Ito E.
Genes Chromosomes & Cancer 2018.10
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Adipsic Hypernatremia Without Hypothalamic Lesions Accompanied by Autoantibodies to Subfornical Organ
Hiyama TY, Utsunomiya AN, Matsumoto M, Fujikawa A, Lin CH, Hara K, Kagawa R, Okada S, Kobayashi M, Ishikawa M, Anzo M, Cho H, Takayasu S, Nigawara T, Daimon M, Sato T, Terui K, Ito E, Noda M
Brain Pathology 2017.5
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ダイアモンド・ブラックファン貧血
「佐藤知彦」「伊藤悦朗」
内科 2012.6
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Down症候群関連骨髄増殖症の発症機構
「佐藤知彦」「伊藤悦朗」
血液・腫瘍科 2010.2
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Mizoribine oral pulse therapy for a patient with severe lupus nephritis
Hiroshi Tanaka, Koichi Suzuki, Tohru Nakahata, Tomohiko Sato, Etsuro Ito
Pediatric International 2003.8
Review Papers
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Down症候群に関連した骨髄性白血病
佐藤知彦、照井君典
日本臨床 2024.2
Awards
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小児血液学会賞
2009.08