日本内科学会

Predictors for all-cause mortality in men after transcatheter aortic valve replacement: A report from the LAPLACE-TAVI registry.

Kota Nishida, Mike Saji, Ryosuke Higuchi, Itaru Takamisawa, Mamoru Nanasato, Harutoshi Tamura, Kei Sato, Hiroaki Yokoyama, Shinichiro Doi, Shinya Okazaki, Takayuki Onishi, Tetsuya Tobaru, Shuichiro Takanashi, Kazuyuki Ozaki, Takayuki Inomata, Mitsuaki Isobe.

IJC Heart and Vascurature   2023年08月

Impact of periprocedural bleeding on mid-term outcome in nonagenarians who underwent transcatheter aortic valve implantation: insights from LAPLACE registry

Fukutomi M, Onishi T, Ando T, Higuchi R, Hagiya K, Saji M, Takamisawa I, Iguchi N, Takayama M, Shimizu A, Shimizu J, Doi S, Okazaki S, Sato K, Tamura H, Yokoyama H, Takanashi S, Tobaru T.

J Thromb Thrombolysis .   2023年07月

Mid-term Outcome of the Underweight Undergoing Transcatheter Aortic Valve Implantation: an Insight from the LAPLACE-TAVI Registry

Tezuka T, Higuchi R, Hagiya K, Saji M, Takamisawa I, Nanasato M, Iguchi N, Shimizu A, Shimizu J, Doi S, Okazaki S, Sato K, Tamura H, Yokoyama H, Onishi T, Tobaru T, Takanash S, Takayama M.

JACC Asia   2023年

Favorable prognosis in patients with recovered pulmonary hypertension by TAVI: an analysis of the LAPLACE-TAVI registry

Takuma Koike, Hiroshi Iwata, Yuichi Chikata, Shinichiro Doi, Ryo Naito, Hidetoshi Yasuda, Takehiro Funamizu, Hirohisa Endo, Sakiko Miyazaki, Shinya Okazaki, Ryosuke Higuchi, Itaru Takamisawa, Kei Sato, Harutoshi Tamura, Hiroaki Yokoyama, Tetsuya Tobaru, Shuichiro Takanashi, Minoru Tabata, Tohru Minamino.

J Clin Med   2023年

Comparison of procedural and clinical outcomes between optical coherence tomography and intravascular ultrasound guided percutaneous coronary intervention for patients with acute coronary syndrome.

Shun Shikanai, Takashi Yokota, Hiroaki Yokoyama, Takanobu Soma, Shuntaro Sakai, Yuya Sorimachi, Shogo Hamaura, Ken Yamazaki, Michiko Tsushima, Maiko Senoo, Hiroaki Ichikawa, Fumie Nishizaki, Shuji Shibutani, Kenji Hanada, and Hirofumi Tomita.

2023年

Successful Bailout from the Entrapment of Self-Expanding Transcatheter Aortic Valve System caused by the Under-Expanded Deployed Valve.

Yokoyama H, Saito Y, Senoo M, Yokota T, Tobaru T, and Tomita H.

Cardiovasc Interv Ther.   2022年02月

Reduced Left Ventricular Ejection Fraction Is a Risk for Sudden Cardiac Death in the Early Period After Hospital Discharge in Patients With Acute Myocardial Infarction.

Hanada K, Sasaki S, Seno M, Kimura Y, Ichikawa H, Nishizaki F, Yokoyama H, Yokota T, Okumura K, Tomita H.

Circ J   2022年

Prognostic Impact of Diabetes Mellitus on Clinical Outcomes in Lean Patients With Acute Myocardial Infarction.

Hamadate M, Yokoyama H, Sakai S, Shikanai S, Sorimachi Y, Yamazaki K, Kitayama K, Miura N, Yokota T, Tomita H.

In Vivo   2022年

Clinical impact of complete atrioventricular block in patients with ST-segment elevation myocardial infarction.

Yosuke Kawamura, Hiroaki Yokoyama, Kazutaka Kitayama, Naotake Miura, Misato Hamadate, Daiki Nagawa, Masashi Nozaka, Masamichi Nakata, Fumie Nishizaki, Kenji Hanada, Takashi Yokota, Masahiro Yamada, Takumi Higuma, Hirofumi Tomita

Clinical cardiology   44 ( 1 )   91 - 99   2021年01月

Clinical impact of complete atrioventricular block in patients with ST-segment elevation myocardial infarction.

Kawamura Y, Yokoyama H, Kitayama K, Miura N, Hamadate M, Nagawa D, Nozaka M, Nakata M, Nishizaki F, Hanada K, Yokota T, Yamada M, Higuma T, Tomita H

Clinical cardiology   44 ( 1 )   91 - 99   2021年01月

Clinical Outcomes of Acute Myocardial Infarction Patients With a History of Malignant Tumor.

Masashi Nozaka, Hiroaki Yokoyama, Kazutaka Kitayama, Daiki Nagawa, Misato Hamadate, Naotake Miura, Yosuke Kawamura, Masamichi Nakata, Fumie Nishizaki, Kenji Hanada, Takashi Yokota, Masahiro Yamada, Hirofumi Tomita

In vivo (Athens, Greece)   34 ( 6 )   3589 - 3595   2020年11月

Clinical Outcomes of Acute Myocardial Infarction Patients With a History of Malignant Tumor.

Nozaka M, Yokoyama H, Kitayama K, Nagawa D, Hamadate M, Miura N, Kawamura Y, Nakata M, Nishizaki F, Hanada K, Yokota T, Yamada M, Tomita H

In vivo (Athens, Greece)   34 ( 6 )   3589 - 3595   2020年11月

What Is the Optimal Dual Antiplatelet Therapy Strategy After Percutaneous Coronary Intervention in the Era of New-Generation Drug-Eluting Stent?

Hiroaki Yokoyama

Circulation journal : official journal of the Japanese Circulation Society   84 ( 9 )   1459 - 1460   2020年08月

What Is the Optimal Dual Antiplatelet Therapy Strategy After Percutaneous Coronary Intervention in the Era of New-Generation Drug-Eluting Stent?

Yokoyama Hiroaki

Circulation Journal   84 ( 9 )   1459 - 1460   2020年

Incidence and clinical impact of thrombus after stent implantation in patients with ST-segment elevation myocardial infarction: an optical coherence tomography study

Kato Tomo, Yokota Takashi, Kitayama Kazutaka, Miura Naotake, Nozaka Masashi, Tsushima Michiko, Kudo Natsumi, Yokono Yoshikazu, Toyama Yuichi, Endo Tomohide, Nishizaki Fumie, Hanada Kenji, Yokoyama Hiroaki, Yamada Masahiro, Tomita Hirofumi

弘前医学   70 ( 2 )   139 - 147   2020年

Prognostic impact of body mass index and culprit lesion calcification in patients with acute myocardial infarction.

Hiroaki Yokoyama, Takumi Higuma, Tomohide Endo, Fumie Nishizaki, Kenji Hanada, Takashi Yokota, Masahiro Yamada, Ken Okumura, Hirofumi Tomita

Heart and vessels   34 ( 12 )   1909 - 1916   2019年12月

Prognostic impact of body mass index and culprit lesion calcification in patients with acute myocardial infarction.

Yokoyama H, Higuma T, Endo T, Nishizaki F, Hanada K, Yokota T, Yamada M, Okumura K, Tomita H

Heart and vessels   34 ( 12 )   1909 - 1916   2019年12月

Bailout from Guideplus entrapment by coronary stent.

Ryosuke Higuchi, Hiroaki Yokoyama, Kenichi Hagiya, Itaru Takamisawa, Tetsuya Tobaru

Cardiovascular intervention and therapeutics   34 ( 4 )   375 - 376   2019年10月

Bailout from Guideplus entrapment by coronary stent.

Higuchi R, Yokoyama H, Hagiya K, Takamisawa I, Tobaru T

Cardiovascular intervention and therapeutics   34 ( 4 )   375 - 376   2019年10月

Long-term outcomes in Japanese nonagenarians undergoing transcatheter aortic valve implantation: A multi-center analysis.

Hiroaki Yokoyama, Tetsuya Tobaru, Yuki Muto, Kenichi Hagiya, Ryosuke Higuchi, Mike Saji, Itaru Takamisawa, Jun Shimizu, Shuichiro Takanashi, Morimasa Takayama, Hirofumi Tomita, Harutoshi Tamura, Shinichiro Doi, Shinya Okazaki, Mitsuaki Isobe

Clinical cardiology   42 ( 6 )   605 - 611   2019年06月

Long-term outcomes in Japanese nonagenarians undergoing transcatheter aortic valve implantation: A multi-center analysis.

Yokoyama H, Tobaru T, Muto Y, Hagiya K, Higuchi R, Saji M, Takamisawa I, Shimizu J, Takanashi S, Takayama M, Tomita H, Tamura H, Doi S, Okazaki S, Isobe M

Clinical cardiology   42 ( 6 )   605 - 611   2019年06月

Prognostic Impact of Snow Shoveling for Patients with Acute Myocardial Infarction

Senoo Maiko, Yokoyama Hiroaki, Kato Tomo, Kudo Natsumi, Yokono Yoshikazu, Tsushima Michiko, Toyama Yuichi, Narita Noritomo, Narita Masato, Tomita Hirofumi

弘前医学   69 ( 1 )   136 - 145   2019年

海野論文に対するEditorial Comment:─ハートチームの重要性

横山 公章

心臓   51 ( 8 )   815 - 815   2019年

Reply to the Letter to the Editor "'30-minute-delta' and biological variation of high-sensitivity cardiac troponin I".

Hiroaki Yokoyama, Hirofumi Tomita

Journal of cardiology   72 ( 6 )   506 - 507   2018年12月

Prasugrel versus clopidogrel for residual thrombus burden in patients with ST-segment elevation myocardial infarction: an optical coherence tomography study.

Takashi Yokota, Takumi Higuma, Tomohide Endo, Fumie Nishizaki, Kenji Hanada, Hiroaki Yokoyama, Masahiro Yamada, Ken Okumura, Hirofumi Tomita

Coronary artery disease   29 ( 8 )   663 - 669   2018年12月

Prasugrel versus clopidogrel for residual thrombus burden in patients with ST-segment elevation myocardial infarction: an optical coherence tomography study.

Yokota T, Higuma T, Endo T, Nishizaki F, Hanada K, Yokoyama H, Yamada M, Okumura K, Tomita H

Coronary artery disease   29 ( 8 )   663 - 669   2018年12月

Reply to the Letter to the Editor "'30-minute-delta' and biological variation of high-sensitivity cardiac troponin I".

Yokoyama H, Tomita H

Journal of cardiology   72 ( 6 )   506 - 507   2018年12月

Neoatherosclerosis 5 Years After Bioresorbable Vascular Scaffold Implantation.

Noriaki Moriyama, Koki Shishido, Yutaka Tanaka, Shohei Yokota, Takahiro Hayashi, Hirokazu Miyashita, Tatsuya Koike, Hiroaki Yokoyama, Takuma Takada, Takashi Nishimoto, Tomoki Ochiai, Kazuki Tobita, Futoshi Yamanaka, Shingo Mizuno, Masato Murakami, Saeko Takahashi, Shigeru Saito

Journal of the American College of Cardiology   71 ( 17 )   1882 - 1893   2018年05月

"30-minute-delta" of high-sensitivity troponin I improves diagnostic performance in acute myocardial infarction.

Hiroaki Yokoyama, Takumi Higuma, Tomohide Endo, Fumie Nishizaki, Kenji Hanada, Takashi Yokota, Masahiro Yamada, Ken Okumura, Hirofumi Tomita

Journal of cardiology   71 ( 2 )   144 - 148   2018年02月

"30-minute-delta" of high-sensitivity troponin I improves diagnostic performance in acute myocardial infarction.

Yokoyama H, Higuma T, Endo T, Nishizaki F, Hanada K, Yokota T, Yamada M, Okumura K, Tomita H

Journal of cardiology   71 ( 2 )   144 - 148   2018年02月

Use of Wearable Cardioverter Defibrillator Shortens the ICU Stay and Enables Safe Management in a General Ward

Shoji Yoshihiro, Sasaki Shingo, Toyama Yuichi, Nishizaki Kimitaka, Kinjo Takahiko, Ishida Yuji, Endo Tomohide, Nishizaki Fumie, Itoh Taihei, Yokota Takashi, Yokoyama Hiroaki, Yamada Masahiro, Horiuchi Daisuke, Kimura Masaomi, Higuma Takumi, Okumura Ken, Tomita Hirofumi

弘前医学   68 ( 2 )   135 - 141   2018年

Morphological predictors for no reflow phenomenon after primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction caused by plaque rupture.

Tsunenari Soeda, Takumi Higuma, Naoki Abe, Masahiro Yamada, Hiroaki Yokoyama, Shuji Shibutani, Daniel S Ong, Rocco Vergallo, Yoshiyasu Minami, Hang Lee, Ken Okumura, Ik-Kyung Jang

European heart journal cardiovascular Imaging   18 ( 1 )   103 - 110   2017年01月

Potential roles of the wearable cardioverter-defibrillator in acute phase care of patients at high risk of sudden cardiac death: A single-center Japanese experience.

Shingo Sasaki, Yoshihiro Shoji, Yuji Ishida, Takahiko Kinjo, Yuichi Tsushima, Maiko Seno, Fumie Nishizaki, Taihei Itoh, Kei Izumiyama, Takashi Yokota, Hiroaki Yokoyama, Masahiro Yamada, Daisuke Horiuchi, Masaomi Kimura, Takumi Higuma, Hirofumi Tomita, Ken Okumura

Journal of cardiology   69 ( 1 )   359 - 363   2017年01月

Morphological predictors for no reflow phenomenon after primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction caused by plaque rupture.

Soeda T, Higuma T, Abe N, Yamada M, Yokoyama H, Shibutani S, Ong DS, Vergallo R, Minami Y, Lee H, Okumura K, Jang IK

European heart journal. Cardiovascular Imaging   18 ( 1 )   103 - 110   2017年01月

Potential roles of the wearable cardioverter-defibrillator in acute phase care of patients at high risk of sudden cardiac death: A single-center Japanese experience.

Sasaki S, Shoji Y, Ishida Y, Kinjo T, Tsushima Y, Seno M, Nishizaki F, Itoh T, Izumiyama K, Yokota T, Yokoyama H, Yamada M, Horiuchi D, Kimura M, Higuma T, Tomita H, Okumura K

Journal of cardiology   69 ( 1 )   359 - 363   2017年01月

Does Residual Thrombus After Aspiration Thrombectomy Affect the Outcome of Primary PCI in Patients With ST-Segment Elevation Myocardial Infarction?: An Optical Coherence Tomography Study.

Takumi Higuma, Tsunenari Soeda, Masahiro Yamada, Takashi Yokota, Hiroaki Yokoyama, Kei Izumiyama, Fumie Nishizaki, Yoshiyasu Minami, Lei Xing, Erika Yamamoto, Hang Lee, Ken Okumura, Ik-Kyung Jang

JACC. Cardiovascular interventions   9 ( 19 )   2002 - 2011   2016年10月

Does Residual Thrombus After Aspiration Thrombectomy Affect the Outcome of Primary PCI in Patients With ST-Segment Elevation Myocardial Infarction?: An Optical Coherence Tomography Study.

Higuma T, Soeda T, Yamada M, Yokota T, Yokoyama H, Izumiyama K, Nishizaki F, Minami Y, Xing L, Yamamoto E, Lee H, Okumura K, Jang IK

JACC. Cardiovascular interventions   9 ( 19 )   2002 - 2011   2016年10月

Coronary Plaque Characteristics Associated With Reduced TIMI (Thrombolysis in Myocardial Infarction) Flow Grade in Patients With ST-Segment-Elevation Myocardial Infarction: A Combined Optical Coherence Tomography and Intravascular Ultrasound Study.

Takumi Higuma, Tsunenari Soeda, Masahiro Yamada, Takashi Yokota, Hiroaki Yokoyama, Fumie Nishizaki, Lei Xing, Erika Yamamoto, Krzysztof Bryniarski, Jiannan Dai, Hang Lee, Ken Okumura, Ik-Kyung Jang

Circulation. Cardiovascular interventions   9 ( 9 )   2016年09月

Coronary Plaque Characteristics Associated With Reduced TIMI (Thrombolysis in Myocardial Infarction) Flow Grade in Patients With ST-Segment-Elevation Myocardial Infarction: A Combined Optical Coherence Tomography and Intravascular Ultrasound Study.

Higuma T, Soeda T, Yamada M, Yokota T, Yokoyama H, Nishizaki F, Xing L, Yamamoto E, Bryniarski K, Dai J, Lee H, Okumura K, Jang IK

Circulation. Cardiovascular interventions   9 ( 9 )   2016年09月

Coronary Calcification and Plaque Vulnerability: An Optical Coherence Tomographic Study.

Daniel S Ong, Jay S Lee, Tsunenari Soeda, Takumi Higuma, Yoshiyasu Minami, Zhao Wang, Hang Lee, Hiroaki Yokoyama, Takashi Yokota, Ken Okumura, Ik-Kyung Jang

Circulation. Cardiovascular imaging   9 ( 1 )   2016年01月

Coronary Calcification and Plaque Vulnerability: An Optical Coherence Tomographic Study.

Ong DS, Lee JS, Soeda T, Higuma T, Minami Y, Wang Z, Lee H, Yokoyama H, Yokota T, Okumura K, Jang IK

Circulation. Cardiovascular imaging   9 ( 1 )   2016年01月

A Combined Optical Coherence Tomography and Intravascular Ultrasound Study on Plaque Rupture, Plaque Erosion, and Calcified Nodule in Patients With ST-Segment Elevation Myocardial Infarction: Incidence, Morphologic Characteristics, and Outcomes After Percutaneous Coronary Intervention.

Takumi Higuma, Tsunenari Soeda, Naoki Abe, Masahiro Yamada, Hiroaki Yokoyama, Shuji Shibutani, Rocco Vergallo, Yoshiyasu Minami, Daniel S Ong, Hang Lee, Ken Okumura, Ik-Kyung Jang

JACC. Cardiovascular interventions   8 ( 9 )   1166 - 1176   2015年08月

A Combined Optical Coherence Tomography and Intravascular Ultrasound Study on Plaque Rupture, Plaque Erosion, and Calcified Nodule in Patients With ST-Segment Elevation Myocardial Infarction: Incidence, Morphologic Characteristics, and Outcomes After Percutaneous Coronary Intervention.

Higuma T, Soeda T, Abe N, Yamada M, Yokoyama H, Shibutani S, Vergallo R, Minami Y, Ong DS, Lee H, Okumura K, Jang IK

JACC. Cardiovascular interventions   8 ( 9 )   1166 - 1176   2015年08月

Deeply reinverted T wave at 14 days after the onset of first anterior acute myocardial infarction predicts improved left ventricular function at 6 months.

Hiroaki Yokoyama, Hirofumi Tomita, Fumie Nishizaki, Kenji Hanada, Shuji Shibutani, Masahiro Yamada, Naoki Abe, Takumi Higuma, Tomohiro Osanai, Ken Okumura

Clinical cardiology   38 ( 3 )   157 - 163   2015年03月

Deeply reinverted T wave at 14 days after the onset of first anterior acute myocardial infarction predicts improved left ventricular function at 6 months.

Yokoyama H, Tomita H, Nishizaki F, Hanada K, Shibutani S, Yamada M, Abe N, Higuma T, Osanai T, Okumura K

Clinical cardiology   38 ( 3 )   157 - 63   2015年03月

Plasma soluble lectin-like oxidized low-density lipoprotein receptor-1 as a novel prognostic biomarker in patients with ST-segment elevation acute myocardial infarction.

Takumi Higuma, Naoki Abe, Syunta Tateyama, Tomohide Endo, Shuji Shibutani, Hiroaki Yokoyama, Kenji Hanada, Masahiro Yamada, Hirofumi Tomita, Hiroyuki Hanada, Tomohiro Osanai, Noriaki Kume, Ken Okumura

Circulation journal : official journal of the Japanese Circulation Society   79 ( 3 )   641 - 648   2015年

Plasma Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 as a Novel Prognostic Biomarker in Patients With ST-Segment Elevation Acute Myocardial Infarction

Higuma Takumi, Abe Naoki, Tateyama Syunta, Kume Noriaki, Okumura Ken, Abe Naoki, Tateyama Syunta, Endo Tomohide, Shibutani Shuji, Yokoyama Hiroaki, Hanada Kenji, Yamada Masahiro, Tomita Hirofumi

日本循環器學誌   79 ( 3 )   641 - 648   2015年

Low serum eicosapentaenoic acid level is a risk for ventricular arrhythmia in patients with acute myocardial infarction: a possible link to J-waves.

Endo T, Tomita H, Higuma T, Abe N, Kushibiki M, Saitoh S, Yamada M, Yokota T, Echizen T, Yokoyama H, Tateyama S, Suzuki A, Ishida Y, Murakami K, Osanai T, Okumura K

Heart and vessels   29 ( 6 )   847 - 54   2014年11月

Stent malapposition, as a potential mechanism of very late stent thrombosis after bare-metal stent implantation: a case report.

Takumi Higuma, Naoki Abe, Kenji Hanada, Hiroaki Yokoyama, Hirofumi Tomita, Ken Okumura

Cardiovascular revascularization medicine : including molecular interventions   15 ( 3 )   178 - 181   2014年04月

Stent malapposition, as a potential mechanism of very late stent thrombosis after bare-metal stent implantation: a case report.

Higuma T, Abe N, Hanada K, Yokoyama H, Tomita H, Okumura K

Cardiovascular revascularization medicine : including molecular interventions   15 ( 3 )   178 - 81   2014年04月

Low serum eicosapentaenoic acid level is a risk for ventricular arrhythmia in patients with acute myocardial infarction: a possible link to J-waves.

Tomohide Endo, Hirofumi Tomita, Takumi Higuma, Naoki Abe, Motoi Kushibiki, Shin Saitoh, Masahiro Yamada, Takashi Yokota, Takashi Echizen, Hiroaki Yokoyama, Shunta Tateyama, Akiko Suzuki, Yuji Ishida, Kazuo Murakami, Tomohiro Osanai, Ken Okumura

Heart and vessels   2013年11月

Re-elevation of T-wave from day 2 to day 4 after successful percutaneous coronary intervention predicts chronic cardiac systolic dysfunction in patients with first anterior acute myocardial infarction.

Nishizaki F, Tomita H, Yokoyama H, Higuma T, Abe N, Suzuki A, Endo T, Tateyama S, Ishida Y, Osanai T, Okumura K

Heart and vessels   28 ( 6 )   704 - 13   2013年11月

Re-elevation of T-wave from day 2 to day 4 after successful percutaneous coronary intervention predicts chronic cardiac systolic dysfunction in patients with first anterior acute myocardial infarction.

Fumie Nishizaki, Hirofumi Tomita, Hiroaki Yokoyama, Takumi Higuma, Naoki Abe, Akiko Suzuki, Tomohide Endo, Shunta Tateyama, Yuji Ishida, Tomohiro Osanai, Ken Okumura

Heart and vessels   2012年12月

Overexpression of coupling factor 6 attenuates exercise-induced physiological cardiac hypertrophy by inhibiting PI3K/Akt signaling in mice.

Shigeki Sagara, Tomohiro Osanai, Taihei Itoh, Kei Izumiyama, Shuji Shibutani, Kenji Hanada, Hiroaki Yokoyama, Yuko Yamamoto, Takashi Yokota, Hirofumi Tomita, Koji Magota, Ken Okumura

Journal of hypertension   30 ( 4 )   778 - 786   2012年04月

Overexpression of coupling factor 6 attenuates exercise-induced physiological cardiac hypertrophy by inhibiting PI3K/Akt signaling in mice.

Sagara S, Osanai T, Itoh T, Izumiyama K, Shibutani S, Hanada K, Yokoyama H, Yamamoto Y, Yokota T, Tomita H, Magota K, Okumura K

Journal of hypertension   30 ( 4 )   778 - 86   2012年04月

Effects of pravastatin and rosuvastatin on the generation of adiponectin in the visceral adipose tissue in patients with coronary artery disease.

Yokoyama H, Saito S, Daitoku K, Fukuda I, Higuma T, Hanada H, Osanai T, Okumura K

Fundamental & clinical pharmacology   25 ( 3 )   378 - 87   2011年06月

Effects of pravastatin and rosuvastatin on the generation of adiponectin in the visceral adipose tissue in patients with coronary artery disease.

Yokoyama H, Saito S, Daitoku K, Fukuda I, Higuma T, Hanada H, Osanai T, Okumura K.

Fundam Clin Pharmacol   2011年01月

Effects of telmisartan on markers of ventricular remodeling in patients with acute myocardial infarction: comparison with enalapril.

Takashi Yokota, Tomohiro Osanai, Kenji Hanada, Motoi Kushibiki, Naoki Abe, Koichi Oikawa, Hirofumi Tomita, Takumi Higuma, Jin Yokoyama, Hiroyuki Hanada, Ken Okumura

Heart and vessels   25 ( 6 )   460 - 468   2010年11月

Overexpression of coupling factor 6 causes cardiac dysfunction under high-salt diet in mice.

Toshihiro Ashitate, Tomohiro Osanai, Makoto Tanaka, Koji Magota, Takashi Echizen, Kei Izumiyama, Hiroaki Yokoyama, Shuji Shibutani, Kenji Hanada, Hirofumi Tomita, Ken Okumura

Journal of hypertension   28 ( 11 )   2243 - 2251   2010年11月

Overexpression of coupling factor 6 causes cardiac dysfunction under high-salt diet in mice.

Ashitate T, Osanai T, Tanaka M, Magota K, Echizen T, Izumiyama K, Yokoyama H, Shibutani S, Hanada K, Tomita H, Okumura K

Journal of hypertension   28 ( 11 )   2243 - 51   2010年11月

Plasma apelin level is decreased in patients with coronary artery disease.

Yokoyama H, Saito S, Higuma T, Hanada H, Osanai T, Okumura K.

Hirosaki Med J   2010年03月

Novel pro-atherogenic molecule coupling factor 6 is elevated in patients with stroke: a possible linkage to homocysteine.

Osanai T, Fujiwara N, Sasaki S, Metoki N, Saitoh G, Tomita H, Nishimura T, Shibutani S, Yokoyama H, Konta Y, Magota K, Okumura K.

Ann Med   2010年02月

Novel pro-atherogenic molecule coupling factor 6 is elevated in patients with stroke: a possible linkage to homocysteine.

Osanai T, Fujiwara N, Sasaki S, Metoki N, Saitoh G, Tomita H, Nishimura T, Shibutani S, Yokoyama H, Konta Y, Magota K, Okumura K

Annals of medicine   42 ( 1 )   79 - 86   2010年

冠動脈疾患における血中アペリン濃度の減少

横山 公章, 齋藤 新, 樋熊 拓未, 花田 裕之, 長内 智宏, 大徳 和之, 福田 幾夫, 奥村 謙

弘前医学   61 ( 1 )   58 - 64   2010年

アミオダロンのマトリックスメタロプロテイナーゼ-2活性に対する作用--ラット心筋梗塞モデルでの検討

堀内 大輔, 長内 智宏, 越前 崇, Ashitate Toshihiro, Kato Chisato, Yokoyama Hiroaki, Hanada Kenji, Shibutani Shuji, Itoh Taihei, Okumura Ken

弘前醫學   60 ( 1 )   45 - 53   2009年04月

PJ-528 Pravastatin but not Rosuvastatin Increases the Adiponectin Level by Suppressing Oxidative Stress in the Visceral Adipose Tissue in CAD Patients(PJ089,Atherosclerosis (Clinical/Pathophysiology) 1 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Yokoyama Hiroaki, Saitoh Shin, Osanai Tomohiro, Okumura Ken

Circulation journal : official journal of the Japanese Circulation Society   73 ( 0 )   2009年03月

Upregulation of soluble vascular endothelial growth factor receptor type 1 by endogenous prostacyclin inhibitor coupling factor 6 in vascular endothelial cells : a role of acidosis-induced c-Src activation

ECHIZEN Takashi, OSANAI Tomohiro, ASHITATE Toshihiro, YOKOYAMA Hiroaki, SHIBUTANI Shuji, TANAKA Makoto, TOMITA Hirofumi, MAGOTA Koji, OKUMURA Ken

Hypertension research : clinical and experimental : official journal of the Japanese Society of Hypertension   32 ( 3 )   182 - 187   2009年03月

Upregulation of soluble vascular endothelial growth factor receptor type 1 by endogenous prostacyclin inhibitor coupling factor 6 in vascular endothelial cells: a role of acidosis-induced c-Src activation.

Takashi Echizen, Tomohiro Osanai, Toshihiro Ashitate, Hiroaki Yokoyama, Shuji Shibutani, Makoto Tanaka, Hirofumi Tomita, Koji Magota, Ken Okumura

Hypertension research : official journal of the Japanese Society of Hypertension   32 ( 3 )   182 - 187   2009年03月

Upregulation of soluble vascular endothelial growth factor receptor type 1 by endogenous prostacyclin inhibitor coupling factor 6 in vascular endothelial cells: a role of acidosis-induced c-Src activation.

Echizen T, Osanai T, Ashitate T, Yokoyama H, Shibutani S, Tanaka M, Tomita H, Magota K, Okumura K

Hypertension research : official journal of the Japanese Society of Hypertension   32 ( 3 )   182 - 7   2009年03月

Impact of telmisartan on coronary stenting in patients with acute myocardial infarction compared with enalapril.

Jin Yokoyama, Takumi Higuma, Hirofumi Tomita, Naoki Abe, Koichi Oikawa, Takayuki Fujiwara, Takashi Yokota, Hiroaki Yokoyama, Masaomi Kimura, Shingo Sasaki, Hiroyuki Hanada, Tomohiro Osanai, Ken Okumura

International journal of cardiology   132 ( 1 )   114 - 120   2009年02月

Impact of telmisartan on coronary stenting in patients with acute myocardial infarction compared with enalapril.

Yokoyama J, Higuma T, Tomita H, Abe N, Oikawa K, Fujiwara T, Yokota T, Yokoyama H, Kimura M, Sasaki S, Hanada H, Osanai T, Okumura K

International journal of cardiology   132 ( 1 )   114 - 20   2009年02月

アミオダロンのマトリックスメタロプロテイナーゼ-2 活性に対する作用：ラット心筋梗塞モデルでの検討

堀内 大輔, 奥村 謙, 長内 智宏, 越前 崇, 芦立 俊宗, 加藤 千里, 横山 公章, 花田 賢二, 澁谷 修司, 伊藤 太平

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2022年度，循環器内科学・外科学Ⅰ，専門教育科目（学部）

2021年度， 6年　クリニカルクラークシップ ，専門教育科目（学部）

2021年度，5年　臨床実習 ，専門教育科目（学部）

2021年度，循環器内科学・外科学Ⅰ，専門教育科目（学部）

2020年度， 6年　クリニカルクラークシップ ，専門教育科目（学部）

2020年度，5年　臨床実習 ，専門教育科目（学部）

2019年度，循環器内科学・外科学I 医学科3年次，専門教育科目（学部）

2016年度，5年　カテーテルシミュレーター，専門教育科目（学部）

2016年度，5年　臨床実習，専門教育科目（学部）

2016年度，6年　クリニカルクラークシップ，専門教育科目（学部）

2015年度，5年　カテーテルシミュレーター，専門教育科目（学部）

2015年度，5年　臨床実習，専門教育科目（学部）

2014年度，クリニカルクラークシップ，専門教育科目（学部）

2014年度，チュートリアル教育，専門教育科目（学部）

2014年度，臨床実習，専門教育科目（学部）

2013年度，クリニカルクラークシップ，専門教育科目（学部）

2013年度，チュートリアル教育，専門教育科目（学部）

2013年度，臨床実習，専門教育科目（学部）

2012年度，クリニカルクラークシップ，専門教育科目（学部）

2012年度，チュートリアル教育，専門教育科目（学部）

2012年度，臨床実習，専門教育科目（学部）

2011年度，PBL，専門教育科目（学部）

2011年度，クリニカルクラークシップ，専門教育科目（学部）

2011年度，臨床実習，専門教育科目（学部）