日本農芸化学会

Sex-inducing effects toward planarians widely present among parasitic flatworms.

Kiyono Sekii, Soichiro Miyashita, Kentaro Yamaguchi, Ikuma Saito, Yuria Saito, Sayaka Manta, Masaki Ishikawa, Miyu Narita, Taro Watanabe, Riku Ito, Mizuki Taguchi, Ryohei Furukawa, Aoi Ikeuchi, Kayoko Matsuo, Goro Kurita, Takashi Kumagai, Sho Shirakashi, Kazuo Ogawa, Kimitoshi Sakamoto, Ryo Koyanagi, Noriyuki Satoh, Mizuki Sasaki, Takanobu Maezawa, Madoka Ichikawa-Seki, Kazuya Kobayashi

iScience   26 ( 1 )   105776 - 105776   2023.1

Pseudomonas sp. NGC7 as a microbial chassis for glucose-free muconate production from a variety of lignin-derived aromatics and its application to the production from sugar cane bagasse alkaline extract.

Miho Akutsu, Nanase Abe, Chiho Sakamoto, Yuki Kurimoto, Haruka Sugita, Makoto Tanaka, Yudai Higuchi, Kimitoshi Sakamoto, Naofumi Kamimura, Hiroyuki Kurihara, Eiji Masai, Tomonori Sonoki

Bioresource technology   359   127479 - 127479   2022.6

Identification of novel yolk ferritins unique to planarians: planarians supply aluminum rather than iron to vitellaria in egg capsules.

Osamu Kawase, Hisashi Iwaya, Yoshiya Asano, Hiromoto Inoue, Seiya Kudo, Motoki Sasahira, Nobuyuki Azuma, Daisuke Kondoh, Madoka Ichikawa-Seki, Xuenan Xuan, Kimitoshi Sakamoto, Hikaru Okamoto, Hinaki Nakadate, Wataru Inoue, Ikuma Saito, Miyu Narita, Kiyono Sekii, Kazuya Kobayashi

Cell and tissue research   386 ( 2 )   391 - 413   2021.11

Presence of ES1 homolog in the mitochondrial intermembrane space of porcine retinal cells.

Shinto Utsumi, Kimitoshi Sakamoto, Tetsuro Yamashita, Hiroshi Tomita, Eriko Sugano, Kinji Ishida, Eri Ishiyama, Taku Ozaki

Biochemical and biophysical research communications   524 ( 3 )   542 - 548   2020.4

Novel Characteristics of Mitochondrial Electron Transport Chain from Eimeria tenella.

Makoto Matsubayashi, Daniel Ken Inaoka, Keisuke Komatsuya, Takeshi Hatta, Fumiya Kawahara, Kimitoshi Sakamoto, Kenji Hikosaka, Junya Yamagishi, Kazumi Sasai, Tomoo Shiba, Shigeharu Harada, Naotoshi Tsuji, Kiyoshi Kita

Genes   10 ( 1 )   2019.1

Anaerobic respiration coupled with mitochondrial fatty acid synthesis in wax ester fermentation by Euglena gracilis.

Nakazawa M, Ando H, Nishimoto A, Ohta T, Sakamoto K, Ishikawa T, Ueda M, Sakamoto T, Nakano Y, Miyatake K, Inui H

FEBS letters   592 ( 24 )   4020 - 4027   2018.12

Glycerol kinase of African trypanosomes possesses an intrinsic phosphatase activity.

Emmanuel Oluwadare Balogun, Daniel Ken Inaoka, Tomoo Shiba, Suzumi M Tokuoka, Fuyuki Tokumasu, Kimitoshi Sakamoto, Yasutoshi Kido, Paul A M Michels, Yoh-Ichi Watanabe, Shigeharu Harada, Kiyoshi Kita

Biochimica et biophysica acta   1861 ( 11 Pt A )   2830 - 2842   2017.11

The Open Form Inducer Approach for Structure-Based Drug Design.

Daniel Ken Inaoka, Maiko Iida, Toshiyuki Tabuchi, Teruki Honma, Nayoung Lee, Satoshi Hashimoto, Shigeru Matsuoka, Takefumi Kuranaga, Kazuhito Sato, Tomoo Shiba, Kimitoshi Sakamoto, Emmanuel Oluwadare Balogun, Shigeo Suzuki, Takeshi Nara, Josmar Rodrigues da Rocha, Carlos Alberto Montanari, Akiko Tanaka, Masayuki Inoue, Kiyoshi Kita, Shigeharu Harada

PloS one   11 ( 11 )   e0167078 - e0167078   2016.11

Knockdown of the coenzyme Q synthesis gene Smed-dlp1 affects planarian regeneration and tissue homeostasis.

Yumiko Shiobara, Chiaki Harada, Takeshi Shiota, Kimitoshi Sakamoto, Kiyoshi Kita, Saeko Tanaka, Kenta Tabata, Kiyoteru Sekie, Yorihiro Yamamoto, Tomoyasu Sugiyama

Redox biology   6   599 - 606   2015.12

Direct evidence for the atovaquone action on the Plasmodium cytochrome bc1 complex.

Josephine E Siregar, Genji Kurisu, Tamaki Kobayashi, Motomichi Matsuzaki, Kimitoshi Sakamoto, Fumika Mi-ichi, Yoh-ichi Watanabe, Makoto Hirai, Hiroyuki Matsuoka, Din Syafruddin, Sangkot Marzuki, Kiyoshi Kita

Parasitology international   64 ( 3 )   295 - 300   2015.6

Enhancement of protocatechuate decarboxylase activity for the effective production of muconate from lignin-related aromatic compounds.

Tomonori Sonoki, Miyuki Morooka, Kimitoshi Sakamoto, Yuichiro Otsuka, Masaya Nakamura, Jody Jellison, Barry Goodell

Journal of biotechnology   192 Pt A   71 - 77   2014.12

Marked phenotypic differences of endurance performance and exercise-induced oxygen consumption between AMPK and LKB1 deficiency in mouse skeletal muscle: changes occurring in the diaphragm.

Shinji Miura, Yuko Kai, Miki Tadaishi, Yuka Tokutake, Kimitoshi Sakamoto, Clinton R Bruce, Mark A Febbraio, Kiyoshi Kita, Shigeru Chohnan, Osamu Ezaki

American journal of physiology. Endocrinology and metabolism   305 ( 2 )   E213 - E229   2013.7

Structure of the trypanosome cyanide-insensitive alternative oxidase.

Tomoo Shiba, Yasutoshi Kido, Kimitoshi Sakamoto, Daniel Ken Inaoka, Chiaki Tsuge, Ryoko Tatsumi, Gen Takahashi, Emmanuel Oluwadare Balogun, Takeshi Nara, Takashi Aoki, Teruki Honma, Akiko Tanaka, Masayuki Inoue, Shigeru Matsuoka, Hiroyuki Saimoto, Anthony L Moore, Shigeharu Harada, Kiyoshi Kita

Proceedings of the National Academy of Sciences of the United States of America   110 ( 12 )   4580 - 4585   2013.3

Cloning and characterization of hypoxia-inducible factor-1 subunits from Ascaris suum - a parasitic nematode highly adapted to changes of oxygen conditions during its life cycle.

Miho Goto, Hisako Amino, Mikage Nakajima, Naotoshi Tsuji, Kimitoshi Sakamoto, Kiyoshi Kita

Gene   516 ( 1 )   39 - 47   2013.3

Pharmacophore identification of ascofuranone, potent inhibitor of cyanide-insensitive alternative oxidase of Trypanosoma brucei.

Hiroyuki Saimoto, Yasutoshi Kido, Yasushi Haga, Kimitoshi Sakamoto, Kiyoshi Kita

Journal of biochemistry   153 ( 3 )   267 - 273   2013.3

Crystal structure of mitochondrial quinol-fumarate reductase from the parasitic nematode Ascaris suum.

Hironari Shimizu, Arihiro Osanai, Kimitoshi Sakamoto, Daniel Ken Inaoka, Tomoo Shiba, Shigeharu Harada, Kiyoshi Kita

Journal of biochemistry   151 ( 6 )   589 - 592   2012.6

Age-related changes in the activities of respiratory chain complexes and mitochondrial morphology in Drosophila.

Yukiko Oda, Ryoko Yui, Kimitoshi Sakamoto, Kiyoshi Kita, Etsuko T Matsuura

Mitochondrion   12 ( 2 )   345 - 351   2012.3

Ukulactones A and B, new NADH-fumarate reductase inhibitors produced by Penicillium sp. FKI-3389

Mihoko Mori, Hiromi Morimoto, Yong-Pil Kim, Hideaki Ui, Kenichi Nonaka, Rokuro Masuma, Kimitoshi Sakamoto, Kiyoshi Kita, Hiroshi Tomoda, Kazuro Shiomi, Satoshi Omura

Tetrahedron   67 ( 35 )   6582 - 6586   2011.9

Differential Kinetics Activities of Glycerol Kinase among African Trypanosome Species: Phylogenetic and Therapeutic Implications

Mitsuko Ohashi-Suzuki, Yoshisada Yabu, Shigeru Ohshima, Kosuke Nakamura, Yasutoshi Kido, Kimitoshi Sakamoto, Kiyoshi Kita, Nobuo Ohta, Takashi Suzuki

Journal of Veterinary Medical Science   73 ( 5 )   615 - 621   2011.5

Differential Kinetic Activities of Glycerol Kinase among African Trypanosome Species: Phylogenetic and Therapeutic Implications

Mitsuko Ohashi-Suzuki, Yoshisada Yabu, Shigeru Ohshima, Kosuke Nakamura, Yasutoshi Kido, Kimitoshi Sakamoto, Kiyoshi Kita, Nobuo Ohta, Takashi Suzuki

JOURNAL OF VETERINARY MEDICAL SCIENCE   73 ( 5 )   615 - 621   2011.5

Trypanosome alternative oxidase, a potential therapeutic target for sleeping sickness, is conserved among Trypanosoma brucei subspecies

Kosuke Nakamura, Sunao Fujioka, Shinya Fukumoto, Noboru Inoue, Kimitoshi Sakamoto, Haruyuki Hirata, Yasutoshi Kido, Yoshisada Yabu, Takashi Suzuki, Yo-ichi Watanabe, Hiroyuki Saimoto, Hiroshi Akiyama, Kiyoshi Kita

Parasitology International   59 ( 4 )   560 - 564   2010.12

Purification and kinetic characterization of recombinant alternative oxidase from Trypanosoma brucei brucei

Yasutoshi Kido, Kimitoshi Sakamoto, Kosuke Nakamura, Michiyo Harada, Takashi Suzuki, Yoshisada Yabu,Hiroyuki Saimoto, Fumiyuki Yamakura, Daijiro Ohmori, Anthony Moore, Shigeharu Harada, Kiyoshi Kita

Biochimica et Biophysica Acta -Bioenergetics   1797 ( 4 )   443 - 450   2010.4

Contribution of the FAD and quinone binding sites to the production of reactive oxygen species (ROS) from Ascaris suum mitochondrial complex II

Madhavi P Paranagama, Kimitoshi Sakamoto, Hisako Amino, Mutsumi Awano, Hideto Miyoshi, Kiyoshi Kit

Mitochondrion   10 ( 2 )   158 - 165   2010.3

Crystallization and preliminary crystallographic analysis of cyanide-insensitive alternative oxidases from Trypanosoma brucei brucei

Yasutoshi Kido, Tomoo Shiba, Daniel Ken Inaoka, Kimitoshi Sakamoto, Takeshi Nara, Takashi Aoki, Teruki Honma, Akiko Tanaka, Masayuki Inoue, Sigeru Matsuoka, Anthony Moore, Sigeharu Harada, Kiyoshi Kita

Acta Crystallographica Section F   66 ( 3 )   275 - 278   2010.3

Contribution of the FAD and quinone binding sites to the production of reactive oxygen species from Ascaris suum mitochondrial complex II

Madhavi P. Paranagama, Kimitoshi Sakamoto, Hisako Amino, Mutsumi Awano, Hideto Miyoshi, Kiyoshi Kita

MITOCHONDRION   10 ( 2 )   158 - 165   2010.3

Crystallization and preliminary crystallographic analysis of cyanide-insensitive alternative oxidase from Trypanosoma brucei brucei

Yasutoshi Kido, Tomoo Shiba, Daniel Ken Inaoka, Kimitoshi Sakamoto, Takeshi Nara, Takashi Aoki, Teruki Honma, Akiko Tanaka, Masayuki Inoue, Shigeru Matsuoka, Anthony Moore, Shigeharu Harada, Kiyoshi Kita

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS   66 ( Pt 3 )   275 - 278   2010.3

Crystallization of mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode Ascaris suum with specific inhibitor, flutolanil

Arihiro Osanai, Shigeharu Harada, Kimitoshi Sakamoto, Hironari Shimizu, Daniel Ken Inaoka, Kiyoshi Kita

Acta Crystallographica Section F   65 ( 9 )   941 - 944   2009.9

Crystallization of mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode Ascaris suum with the specific inhibitor flutolanil

Arihiro Osanai, Shigeharu Harada, Kimitoshi Sakamoto, Hironari Shimizu, Daniel Ken Inaoka, Kiyoshi Kita

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS   65 ( Pt 9 )   941 - 944   2009.9

Novel Mitochondrial Complex II Isolated from Trypanosoma cruzi is Composed of Twelve Peptides Including a Heterodimeric Ip Subunit

Jorge Morales, Tatsushi Mogi, Shigeru Mineki, Eizo Takashima, Reiko Mineki, Hiroko Hirawake, Kimitoshi Sakamoto. Satoshi Omura, Kiyoshi Kita

The Journal of Biological Chemistry   284 ( 11 )   7255 - 7263   2009.3

Novel Mitochondrial Complex II Isolated from Trypanosoma cruzi Is Composed of 12 Peptides Including a Heterodimeric Ip Subunit

Jorge Morales, Tatsushi Mogi, Shigeru Mineki, Eizo Takashima, Reiko Mineki, Hiroko Hirawake, Kimitoshi Sakamoto, Satoshi Omura, Kiyoshi Kita

JOURNAL OF BIOLOGICAL CHEMISTRY   284 ( 11 )   7255 - 7263   2009.3

A Tightly Bound Quinone Functions in the Ubiquinone Reaction Sites of Quinoprotein Alcohol Dehydrogenase of an Acetic Acid Bacterium, Gluconobacter suboxydans

Kazunobu Matsushita, Yoshiki Kobayashi, Mitsuhiro Mizuguchi, Hirohide Toyama, Osao Adachi, Kimitoshi Sakamoto, Hideto Miyoshi

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   72 ( 10 )   2723 - 2731   2008.10

Structures of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with substrates and products: Atomic resolution insights into mechanisms of dihydroorotate oxidation and fumarate reduction

Daniel Ken Inaoka, Kimitoshi Sakamoto, Hironari Shimizu, Tomoo Shiba, Genji Kurisu, Takeshi Nara, Takashi Aoki, Kiyoshi Kita, Shigeharu Harada

BIOCHEMISTRY   47 ( 41 )   10881 - 10891   2008.10

Change of subunit composition of mitochondrial complex II (succinate-ubiquinone reductase/quinol-fumarate reductase) in Ascaris suum during the migration in the experimental host

Fumiko Iwata, Noniko Shinjyo, Hisako Amino, Kimitoshi Sakamoto, M. Khyrul Islam, Naotoshi Tsuji, Kiyoshi Kita

PARASITOLOGY INTERNATIONAL   57 ( 1 )   54 - 61   2008.3

Anaerobic NADH-fumarate reductase system is predominant in the respiratory chain of Echinococcus multilocularis, providing a novel target for the chemotherapy of alveolar echinococcosis

Jun Matsumoto, Kimitoshi Sakamoto, Noriko Shinjyo, Yasutoshi Kido, Nao Yamamoto, Kinpei Yagi, Hideto Miyoshi, Nariaki Nonaka, Ken Katakura, Kiyoshi Kita, Yuzaburo Oku

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY   52 ( 1 )   164 - 170   2008.1

Trypanosomu cruzi DHOD structure-based design of 5-halogen and 5-alkyl orotate derivatives

Inaoka Daniel K, Nayoung Lee, Sakamoto Kimitoshi, Shimizu Hironari, Shiba Tomoo, Kurisu Genji, Nara Takeshi, Aoki Takashi, Inoue Masayuki, Kita Kiyoshi, Harada Shigeharu

ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES   64   C222   2008

Decursin and decursinol angelate selectively inhibit NADH-fumarate reductase of Ascaris suum

Kazuro Shiomi, Hiroko Hatano, Hiromi Morimoto, Hideaki Ui, Kimitoshi Sakamoto, Kiyoshi Kita, Hiroshi Tomoda, Eun Woo Lee, Tae Ryeon Heo, Hirokazu Kawagishi, Satoshi Omura

PLANTA MEDICA   73 ( 14 )   1478 - 1481   2007.11

Verticipyrone, a new NADH-fumarate reductase inhibitor, produced by Verticillium sp FKI-1083

Hideaki Ui, Kazuro Shiomi, Hideaki Suzuki, Hiroko Hatano, Hiromi Morimoto, Yuichi Yamaguchi, Rokuro Masuma, Toshiaki Sunazuka, Hiroyuki Shimamura, Kimitoshi Sakamoto, Kiyoshi Kita, Hideto Miyoshi, Hiroshi Tomoda, Satoshi Omura

JOURNAL OF ANTIBIOTICS   59 ( 12 )   785 - 790   2006.12

Paecilaminol, a new NADH-fumarate reductase inhibitor, produced by Paecilomyces sp. FKI-0550

Hideaki Ui, Kazuro Shiomi, Hideaki Suzuki, Hiroko Hatano, Hiromi Morimoto, Yuichi Yamaguchi, Rokuro Masuma, Kimitoshi Sakamoto, Kiyoshi Kita, Hideto Miyoshi, Hiroshi Tomoda, Haruo Tanaka, Satoshi Omura

JOURNAL OF ANTIBIOTICS   59 ( 9 )   591 - 596   2006.9

Kinetic mechanism of quinol oxidation by cytochrome bd studied with ubiquinone-2 analogs

Y Matsumoto, E Muneyuki, D Fujita, K Sakamoto, H Miyoshi, M Yoshida, T Mogi

JOURNAL OF BIOCHEMISTRY   139 ( 4 )   779 - 788   2006.4

Identification and characterization of amino acid residues essential for the active site of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Staphylococcus aureus

S Nishida, K Kurokawa, M Matsuo, K Sakamoto, K Ueno, K Kita, K Sekimizu

JOURNAL OF BIOLOGICAL CHEMISTRY   281 ( 3 )   1714 - 1724   2006.1

Mass spectrometric analysis of the ubiquinol-binding site in cytochrome bd from Escherichia coli

Y Matsumoto, M Murai, D Fujita, K Sakamoto, H Miyoshi, M Yoshida, T Mogi

JOURNAL OF BIOLOGICAL CHEMISTRY   281 ( 4 )   1905 - 1912   2006.1

Mutational analysis of the Trypanosoma vivax alternative oxidase: The E(X)(6)Y Motif is conserved in both mitochondrial alternative oxidase and plastid terminal oxidase and is indispensable for enzyme activity

K Nakamura, K Sakamoto, Y Kido, Y Fujimoto, T Suzuki, M Suzuki, Y Yabu, N Ohta, A Tsuda, M Onuma, K Kita

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   334 ( 2 )   593 - 600   2005.8

Alternative oxidase (AOX) genes of African trypanosomes: Phylogeny and evolution of AOX and plastid terminal oxidase families

T Suzuki, T Hashimoto, Y Yabu, PAO Majiwa, S Ohshima, M Suzuki, SH Lu, M Hato, Y Kido, K Sakamoto, K Nakamura, K Kita, N Ohta

JOURNAL OF EUKARYOTIC MICROBIOLOGY   52 ( 4 )   374 - 381   2005.7

Rhodoquinone reaction site of mitochondrial complex I, in parasitic helminth, Ascaris suum

T Yamashita, T Ino, H Miyoshi, K Sakamoto, A Osanai, E Nakamaru-Ogiso, K Kita

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS   1608 ( 2-3 )   97 - 103   2004.2

Direct evidence for cyanide-insensitive quinol oxidase (alternative oxidase) in apicomplexan parasite Cryptosporidium parvum: phylogenetic and therapeutic implications

T Suzuki, T Hashimoto, Y Yabu, Y Kido, K Sakamoto, C Nihei, M Hato, S Suzuki, Y Amano, K Nagai, T Hosokawa, N Minagawa, N Ohta, K Kita

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   313 ( 4 )   1044 - 1052   2004.1

Isolation and characterization of the stage-specific cytochrome b small subunit (CybS) of Ascaris suum complex II from the aerobic respiratory chain of larval mitochondria

H Amino, A Osanai, H Miyadera, N Shinjyo, E Tomitsuka, H Taka, R Mineki, K Murayama, S Takamiya, T Aoki, H Miyoshi, K Sakamoto, S Kojima, K Kita

MOLECULAR AND BIOCHEMICAL PARASITOLOGY   128 ( 2 )   175 - 186   2003.5

Complex II from phototrophic purple bacterium Rhodoferax fermentans displays rhodoquinol-fumarate reductase activity

H Miyadera, A Hiraishi, H Miyoshi, K Sakamoto, R Mineki, K Murayama, KVP Nagashima, K Matsuura, S Kojima, K Kita

EUROPEAN JOURNAL OF BIOCHEMISTRY   270 ( 8 )   1863 - 1874   2003.4

The ND5 subunit was labeled by a photoaffinity analogue of fenpyroximate in bovine mitochondrial complex I

E Nakamaru-Ogiso, K Sakamoto, A Matsuno-Yagi, H Miyoshi, T Yagi

BIOCHEMISTRY   42 ( 3 )   746 - 754   2003.1

Hybrid ubiquinone: novel inhibitor of mitochondrial complex I.

Yabunaka H, Kenmochi A, Nakatogawa Y, Sakamoto K, Miyoshi H

Biochimica et biophysica acta   1556 ( 2-3 )   106 - 112   2002.12

Synthesis of mucin-type glycopeptide (beta hCG 130-145) by on-resin fragment condensation of the glycopeptide segments carrying unmasked oligosaccharides

T Ichiyanagi, M Takatani, K Sakamoto, Y Nakahara, Y Ito, H Hojo, Y Nakahara

TETRAHEDRON LETTERS   43 ( 18 )   3297 - 3300   2002.4

Preparation of glycosylated amino acid derivatives for glycoprotein synthesis by in vitro translation system

S Manabe, K Sakamoto, Y Nakahara, M Sisido, T Hohsaka, Y Ito

BIOORGANIC & MEDICINAL CHEMISTRY   10 ( 3 )   573 - 581   2002.3

Combination of silyl carbamate and amino acid fluoride for solid-phase peptide synthesis

K Sakamoto, Y Nakahara, Y Ito

TETRAHEDRON LETTERS   43 ( 8 )   1515 - 1518   2002.2

Synthesis and electron-transfer activity of azido ubiquinone-2

K Sakamoto, K Nomura, H Miyoshi

JOURNAL OF PESTICIDE SCIENCE   27 ( 2 )   147 - 149   2002

Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans

H Miyadera, H Amino, A Hiraishi, H Taka, K Murayama, H Miyoshi, K Sakamoto, N Ishii, S Hekimi, K Kita

JOURNAL OF BIOLOGICAL CHEMISTRY   276 ( 11 )   7713 - 7716   2001.3

An anthelmintic compound, nafuredin, shows selective inhibition of complex I in helminth mitochondria

S Omura, H Miyadera, H Ui, K Shiomi, Y Yamaguchi, R Masuma, T Nagamitsu, D Takano, T Sunazuka, A Harder, H Kolbl, M Namikoshi, H Miyoshi, K Sakamoto, K Kita

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA   98 ( 1 )   60 - 62   2001.1

Design syntheses and mitochondrial complex I inhibitory activity of novel acetogenin mimics

K Kuwabara, M Takada, J Iwata, K Tatsumoto, K Sakamoto, H Iwamura, H Miyoshi

EUROPEAN JOURNAL OF BIOCHEMISTRY   267 ( 9 )   2538 - 2546   2000.5

Defining the structural domain of subunit II of the heme-copper terminal oxidase using chimeric enzymes constructed from the Escherichia coli bo-type ubiquinol oxidase and the thermophilic Bacillus caa(3)-type cytochrome c oxidase

K Sakamoto, T Mogi, S Noguchi, N Sone

JOURNAL OF BIOCHEMISTRY   126 ( 5 )   934 - 939   1999.11

Characterization of the ubiquinol oxidation sites in cytochromes bo and bd from Escherichia coli using aurachin C analogues

H Miyoshi, K Takegami, K Sakamoto, T Mogi, H Iwamura

JOURNAL OF BIOCHEMISTRY   125 ( 1 )   138 - 142   1999.1

The quinohemoprotein alcohol dehydrogenase of Gluconobacter suboxydans has ubiquinol oxidation activity at a site different from the ubiquinone reduction site

K Matsushita, T Yakushi, H Toyama, O Adachi, H Miyoshi, E Tagami, K Sakamoto

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS   1409 ( 3 )   154 - 164   1999.1

Role of the isoprenyl tail of ubiquinone in reaction with respiratory enzymes: Studies with bovine heart mitochondrial complex I and Escherichia coli bo-type ubiquinol oxidase

K Sakamoto, H Miyoshi, M Ohshima, K Kuwabara, K Kano, T Akagi, T Mogi, H Iwamura

BIOCHEMISTRY   37 ( 43 )   15106 - 15113   1998.10

Isolation and characterizations of quinone analogue-resistant mutants of bo-type ubiquinol oxidase from Escherichia coli

M Sato-Watanabe, T Mogi, K Sakamoto, H Miyoshi, Y Anraku

BIOCHEMISTRY   37 ( 37 )   12744 - 12752   1998.9

Specificity of pyridinium inhibitors of the ubiquinone reduction sites in mitochondrial complex I

H Miyoshi, J Iwata, K Sakamoto, H Furukawa, M Takada, H Iwamura, T Watanabe, Y Kodama

JOURNAL OF BIOLOGICAL CHEMISTRY   273 ( 28 )   17368 - 17374   1998.7

Characterization of the ubiquinone reduction site of mitochondrial complex I using bulky synthetic ubiquinones

M Ohshima, H Miyoshi, K Sakamoto, K Takegami, J Iwata, K Kuwabara, H Iwamura, T Yagi

BIOCHEMISTRY   37 ( 18 )   6436 - 6445   1998.5

Probing the ubiquinone reduction site of mitochondrial complex I using novel cationic inhibitors

H Miyoshi, M Inoue, S Okamoto, M Ohshima, K Sakamoto, H Iwamura

JOURNAL OF BIOLOGICAL CHEMISTRY   272 ( 26 )   16176 - 16183   1997.6

Probing substrate binding site of the Escherichia coli quinol oxidases using synthetic ubiquinol analogues

K Sakamoto, H Miyoshi, K Takegami, T Mogi, Y Anraku, H Iwamura

JOURNAL OF BIOLOGICAL CHEMISTRY   271 ( 47 )   29897 - 29902   1996.11

Comparison of the inhibitory action of synthetic capsaicin analogues with various NADH-ubiquinone oxidoreductases

T Satoh, H Miyoshi, K Sakamoto, H Iwamura

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS   1273 ( 1 )   21 - 30   1996.1

Comparison of the structural features of ubiquinone reduction sites between glucose dehydrogenase in Escherichia coli and bovine heart mitochondrial complex I

Kimitoshi Sakamoto, Hideto Miyoshi, Kazunobu Matsushita, Masato Nakagawa, Junko Ikeda, Michiyo Ohshima, Osao Adachi, Toshio Akagi, Hajime Iwamura

European Journal of Biochemistry   237 ( 1 )   128 - 135   1996