Updated on 2022/01/21

写真a

 
FURUKAWA Tomonori
 
Affiliation
Division of Medical Science Basic Medicine Section
Full-time staff
Graduate School of Medicine Institute for Brain Science Neurophysiology
Laboratory Phone number
+81-172-39-5138
Laboratory Fax number
+81-172-39-5138

Degree

  • Philosophiae Doctor

  • 修士(農学)

Research Interests

  • 生体情報

  • 組織

  • 分子生物

  • 薬理

  • 電気生理

  • 神経

Research Areas

  • Life Science / Cell biology

  • Life Science / Biophysics

  • Life Science / Anesthesiology

Papers

  • The role of neutrophil gelatinase-associated lipocalin and iron homeostasis in object recognition impairment in aged sepsis-survivor rats.

    Nikaido Y, Midorikawa Y, Furukawa T, Shimoyama S, Takekawa D, Kitayama M, Ueno S, Kushikata T, Hirota K

    Scientific reports   12 ( 1 )   249   2022.1

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  • Impaired Cognitive Function and Hippocampal Changes Following Chronic Diazepam Treatment in Middle-Aged Mice.

    Furukawa T, Nikaido Y, Shimoyama S, Masuyama N, Notoya A, Ueno S

    Frontiers in aging neuroscience   13   777404   2021.11

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  • Copy number variations in Japanese children with autism spectrum disorder.

    Yui Sakamoto, Shuji Shimoyama, Tomonori Furukawa, Masaki Adachi, Michio Takahashi, Tamaki Mikami, Michito Kuribayashi, Ayako Osato, Daiki Tsushima, Manabu Saito, Shinya Ueno, Kazuhiko Nakamura

    Psychiatric genetics   31 ( 3 )   79 - 87   2021.6

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  • GABAA Receptors and Maternally Derived Taurine Regulate the Temporal Specification of Progenitors of Excitatory Glutamatergic Neurons in the Mouse Developing Cortex.

    Shiro Tochitani, Tomonori Furukawa, Ryo Bando, Shigeaki Kondo, Takashi Ito, Yoshitaka Matsushima, Toshio Kojima, Hideo Matsuzaki, Atsuo Fukuda

    Cerebral cortex (New York, N.Y. : 1991)   2021.5

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  • Lipopolysaccharide induces mouse translocator protein (18 kDa) expression via the AP-1 complex in the microglial cell line, BV-2.

    Shuji Shimoyama, Tomonori Furukawa, Yoshiki Ogata, Yoshikazu Nikaido, Kohei Koga, Yui Sakamoto, Shinya Ueno, Kazuhiko Nakamura

    PloS one   14 ( 9 )   e0222861 - e0222861   2019.9

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  • Phospholipase C-related inactive protein type-1 deficiency affects anesthetic electroencephalogram activity induced by propofol and etomidate in mice.

    Tomonori Furukawa, Yoshikazu Nikaido, Shuji Shimoyama, Yoshiki Ogata, Tetsuya Kushikata, Kazuyoshi Hirota, Takashi Kanematsu, Masato Hirata, Shinya Ueno

    Journal of anesthesia   33 ( 4 )   531 - 542   2019.7

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  • Lipopolysaccharide induces mouse translocator protein (18 kDa) expression via the AP-1 complex in the microglial cell line, BV-2.

    Shimoyama S, Furukawa T, Ogata Y, Nikaido Y, Koga K, Sakamoto Y, Ueno S, Nakamura K

    PloS one   14 ( 9 )   e0222861   2019

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  • 〈一般演題抄録〉遺伝子<i>Tspo</i> の発現制御メカニズムの解明

    下山 修司, 古川 智範, 小潟 佳輝, 中村 和彦, 上野 伸哉

    弘前医学   69 ( 1 )   207   2019

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  • Anti-hypersensitive effect of angiotensin 1-7 on streptozotocin-induced diabetic neuropathic pain in mice

    Ogata Yoshiki, Nemoto Wataru, Yamagata Ryota, Nakagawasai Osamu, Shimoyama Shuji, Furukawa Tomonori, Ueno Shinya, Tan-No Koichi

    European Journal of Pain   23 ( 4 )   739 - 749   2018.11

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  • Chronic inflammatory pain induced GABAergic synaptic plasticity in the adult mouse anterior cingulate cortex.

    Molecular Pain   14 ( 14 )   1 - 14   2018.6

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  • MHC Class I in Dopaminergic Neurons Suppresses Relapse to Reward Seeking

    Murakami Gen, Edamura Mitsuhiro, Furukawa Tomonori, Kawasaki Hideya, Kosugi Isao, Fukuda Atsuo, Iwashita Toshihide and Nakahara Daiichiro

    Science Advances   2018.3

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  • MHC class I in dopaminergic neurons suppresses relapse to reward seeking.

    Murakami G, Edamura M, Furukawa T, Kawasaki H, Kosugi I, Fukuda A, Iwashita T, Nakahara D

    Science advances   4 ( 3 )   eaap7388   2018.3

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  • Propofol Anesthesia Is Reduced in Phospholipase C-Related Inactive Protein Type-1 Knockout Mice.

    Nikaido Y, Furukawa T, Shimoyama S, Yamada J, Migita K, Koga K, Kushikata T, Hirota K, Kanematsu T, Hirata M, Ueno S

    The Journal of pharmacology and experimental therapeutics   361 ( 3 )   367 - 374   2017.6

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  • Propofol Anesthesia Is Reduced in Phospholipase C-Related Inactive Protein Type-1 Knockout Mice.

    Nikaido Y, Furukawa T, Shimoyama S, Yamada J, Migita K, Koga K, Kushikata T, Hirota K, Kanematsu T, Hirata M, Ueno S.

    J Pharmacol Exp Ther   361 ( 3 )   367 - 374   2017.4

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  • Activations of muscarinic M1 receptors in the anterior cingulate cortex contribute to the antinociceptive effect via GABAergic transmission

    Kohei Koga, Yu Matsuzaki, Kenji Honda, Fumihiro Eto, Tomonori Furukawa, Keisuke Migita, Keiichi Irie, Kenichi Mishima, Shinya Ueno

    Molecular Pain   13   1 - 11   2017.2

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  • Chronic diazepam administration increases the expression of Lcn2 in the CNS

    Tomonori Furukawa, Shuji Shimoyama, Yasuo Miki, Yoshikazu Nikaido, Kohei Koga, Kazuhiko Nakamura, Koichi Wakabayashi, Shinya Ueno

    Pharmacology Research & Perspectives   5 ( 1 )   e00283   2017.1

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  • 〈一般演題抄録〉うつ病モデルラットは内側前頭前野機能異常を起こす

    二階堂 義和, 古川 智範, 下山 修司, 古賀 浩平, 上野 伸哉

    弘前医学   67 ( 2 )   185   2017

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  • 〈一般演題抄録〉ジアゼパム長期投与マウス脳組織のトランスクリプトーム解析

    古川 智範, 下山 修司, 二階堂 義和, 古賀 浩平, 中村 和彦, 上野 伸哉

    弘前医学   67 ( 2 )   186   2017

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  • 〈一般演題抄録〉ジアゼパム長期投与マウスにおける脳内 Lcn2 発現および認知機能の解析

    古川 智範, 二階堂 義和, 下山 修司, 三木 康生, 古賀 浩平, 中村 和彦, 若林 孝一, 上野 伸哉

    弘前医学   68 ( 1 )   88   2017

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  • HSP90 Regulation of P2X7 Receptor Function Requires an Intact Cytoplasmic C-Terminus.

    Keisuke Migita, Taku Ozaki, Shuji Shimoyama, Junko Yamada, Yoshikazu Nikaido, Tomonori Furukawa, Yuko Shiba, Terrance M Egan, Shinya Ueno

    Molecular pharmacology   90 ( 2 )   116 - 126   2016.8

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  • HSP90 Regulation of P2X7 Receptor Function Requires an Intact Cytoplasmic C-Terminus.

    Migita K, Ozaki T, Shimoyama S, Yamada J, Nikaido Y, Furukawa T, Shiba Y, Egan TM, Ueno S

    Molecular pharmacology   90 ( 2 )   116 - 26   2016.8

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  • cis-3-Hexenol and trans-2-hexenal mixture prevents development of PTSD-like phenotype in rats.

    Yoshikazu Nikaido, Junko Yamada, Keisuke Migita, Yuko Shiba, Tomonori Furukawa, Toshihiro Nakashima, Shinya Ueno

    Behavioural brain research   297   251 - 258   2016.1

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  • cis-3-Hexenol and trans-2-hexenal mixture prevents development of PTSD-like phenotype in rats.

    Nikaido Y, Yamada J, Migita K, Shiba Y, Furukawa T, Nakashima T, Ueno S

    Behavioural brain research   297   251 - 8   2016.1

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  • GABA<sub>A</sub> 受容体応答の制御機構

    上野 伸哉, 古川 智範, 二階堂 義和, 下山 修司, 柴 祐子, 山田 順子

    弘前医学   66 ( 2 )   105 - 109   2016

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  • Activity-dependent endogenous taurine release facilitates excitatory neurotransmission in the neocortical marginal zone of neonatal rats.

    Qian T, Chen R, Nakamura M, Furukawa T, Kumada T, Akita T, Kilb W, Luhmann HJ, Nakahara D, Fukuda A

    Frontiers in cellular neuroscience   8   33   2014

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  • Roles of taurine-mediated tonic GABAA receptor activation in the radial migration of neurons in the fetal mouse cerebral cortex.

    Furukawa T, Yamada J, Akita T, Matsushima Y, Yanagawa Y, Fukuda A

    Frontiers in cellular neuroscience   8   88   2014

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  • De Novo mutations in GNAO1, encoding a Gαo subunit of heterotrimeric G proteins, cause epileptic encephalopathy.

    Nakamura K, Kodera H, Akita T, Shiina M, Kato M, Hoshino H, Terashima H, Osaka H, Nakamura S, Tohyama J, Kumada T, Furukawa T, Iwata S, Shiihara T, Kubota M, Miyatake S, Koshimizu E, Nishiyama K, Nakashima M, Tsurusaki Y, Miyake N, Hayasaka K, Ogata K, Fukuda A, Matsumoto N, Saitsu H

    American journal of human genetics   93 ( 3 )   496 - 505   2013.9

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  • Cl⁻ homeodynamics in gap junction-coupled astrocytic networks on activation of GABAergic synapses.

    Egawa K, Yamada J, Furukawa T, Yanagawa Y, Fukuda A

    The Journal of physiology   591 ( 16 )   3901 - 17   2013.8

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  • Guidepost neurons for the lateral olfactory tract: expression of metabotropic glutamate receptor 1 and innervation by glutamatergic olfactory bulb axons.

    Tatsumi Hirata, Tatsuro Kumada, Takahiko Kawasaki, Tomonori Furukawa, Atsu Aiba, François Conquet, Yumiko Saga, Atsuo Fukuda

    Developmental neurobiology   72 ( 12 )   1559 - 1576   2012.12

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  • Guidepost neurons for the lateral olfactory tract: expression of metabotropic glutamate receptor 1 and innervation by glutamatergic olfactory bulb axons.

    Hirata T, Kumada T, Kawasaki T, Furukawa T, Aiba A, Conquet F, Saga Y, Fukuda A

    Developmental neurobiology   72 ( 12 )   1559 - 76   2012.12

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  • Taurine inhibits K+-Cl- cotransporter KCC2 to regulate embryonic Cl- homeostasis via with-no-lysine (WNK) protein kinase signaling pathway.

    Inoue K, Furukawa T, Kumada T, Yamada J, Wang T, Inoue R, Fukuda A

    The Journal of biological chemistry   287 ( 25 )   20839 - 50   2012.6

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  • The physiological roles of vesicular GABA transporter during embryonic development: a study using knockout mice.

    Saito K, Kakizaki T, Hayashi R, Nishimaru H, Furukawa T, Nakazato Y, Takamori S, Ebihara S, Uematsu M, Mishina M, Miyazaki J, Yokoyama M, Konishi S, Inoue K, Fukuda A, Fukumoto M, Nakamura K, Obata K, Yanagawa Y

    Molecular brain   3   40   2010.12

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  • Low-concentration tributyltin perturbs inhibitory synaptogenesis and induces neuronal death in immature but not mature neurons.

    Yamada J, Inoue K, Furukawa T, Fukuda A

    Toxicology letters   198 ( 2 )   282 - 8   2010.10

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  • GABA imaging in brain slices using immobilized enzyme-linked photoanalysis.

    Morishima T, Uematsu M, Furukawa T, Yanagawa Y, Fukuda A, Yoshida S

    Neuroscience research   67 ( 4 )   347 - 53   2010.8

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  • Dominant-negative mutations in alpha-II spectrin cause West syndrome with severe cerebral hypomyelination, spastic quadriplegia, and developmental delay.

    Saitsu H, Tohyama J, Kumada T, Egawa K, Hamada K, Okada I, Mizuguchi T, Osaka H, Miyata R, Furukawa T, Haginoya K, Hoshino H, Goto T, Hachiya Y, Yamagata T, Saitoh S, Nagai T, Nishiyama K, Nishimura A, Miyake N, Komada M, Hayashi K, Hirai S, Ogata K, Kato M, Fukuda A, Matsumoto N

    American journal of human genetics   86 ( 6 )   881 - 91   2010.6

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  • Molecular basis for the GABAA receptor-mediated tonic inhibition in rat somatosensory cortex.

    Yamada J, Furukawa T, Ueno S, Yamamoto S, Fukuda A

    Cerebral cortex (New York, N.Y. : 1991)   17 ( 8 )   1782 - 7   2007.8

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  • Insertion of alpha7 nicotinic receptors at neocortical layer V GABAergic synapses is induced by a benzodiazepine, midazolam.

    Yamamoto S, Yamada J, Ueno S, Kubota H, Furukawa T, Yamamoto S, Fukuda A

    Cerebral cortex (New York, N.Y. : 1991)   17 ( 3 )   653 - 60   2007.3

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  • GABA-A receptors regulate neocortical neuronal migration in vitro and in vivo.

    Heck N, Kilb W, Reiprich P, Kubota H, Furukawa T, Fukuda A, Luhmann HJ

    Cerebral cortex (New York, N.Y. : 1991)   17 ( 1 )   138 - 48   2007.1

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  • Differential expression of KCC2 accounts for the differential GABA responses between relay and intrinsic neurons in the early postnatal rat olfactory bulb.

    Wang C, Ohno K, Furukawa T, Ueki T, Ikeda M, Fukuda A, Sato K

    The European journal of neuroscience   21 ( 5 )   1449 - 55   2005.3

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  • Brain oxytocin augments stress-induced long-lasting plasma adrenocorticotropic hormone elevation in rats.

    Nakashima T, Noguchi T, Furukawa T, Yamasaki M, Makino S, Miyata S, Kiyohara T

    Neuroscience letters   321 ( 3 )   161 - 4   2002.3

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Review Papers

  • GABAA受容体応答の制御機構

    上野伸哉,古川智範,二階堂義和,下山修司,柴祐子,山田, 順子

    弘前医学   2016.3

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Awards

  • 弘前医学会例会優秀発表賞

    2017.01