Papers - FURUKAWA Tomonori
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Intranasal administration of trehalose reduces α-synuclein oligomers and accelerates α-synuclein aggregation.
Makoto T Tanaka, Yasuo Miki, Fumiaki Mori, Tomoya Kon, Tomonori Furukawa, Shuji Shimoyama, Yota Tatara, Taku Ozaki, Conceição Bettencourt, Thomas T Warner, Koichi Wakabayashi
Brain communications 6 ( 4 ) fcae193 2024.8
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Effects of voluntary and forced exercise on brain health in adult rats.
Sato C, Chiba M, Furukawa T, Koeda S, Mikami M, Hatakenaka K, Nunomura T, Umamichi K, Miura H, Yamada J.
Journal of Brain Science 2024.3
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Sex-related differences in the effect of exercise on protein profiles of serum in mice.
Furukawa T, Shimoyama S, Kobayashi A, Tatara Y, Nikaido Y, Ueno S
Hirosaki Medical Journal 74 2024.3
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Benzodiazepine-induced cell growth inhibition via GABAA receptor- and TSPO- independent pathways
Shimoyama S, Furukawa T, Ueno S
Hirosaki Medical Journal 74 2024.3
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Attempt to Develop Therapeutic Drug for Autism by Targeting IGF-1: Exploration of Small Compounds for IGF-1 Gene Expression
Nakamura, K; Shimoyama, S; Sakamoto, Y; Furukawa, T; Hasegawa, A; Shimizu, R; Kojima, H; Ueno, S
NEUROPSYCHOPHARMACOLOGY 48 128 - 128 2023.12
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Intranasal administration of trehalose reduces α-synuclein oligomers by accelerating aggregate formation in a mouse model of multiple system atrophy
Tanaka, M; Miki, Y; Mori, F; Furukawa, T; Shimoyama, S; Tatara, Y; Wakabayashi, K
BRAIN PATHOLOGY 33 2023.9
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Maternal taurine as a modulator of Cl- homeostasis as well as of glycine/GABAA receptors for neocortical development.
Tomonori Furukawa, Atsuo Fukuda
Frontiers in cellular neuroscience 17 1221441 - 1221441 2023.8
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Altered Amantadine Effects after Repetitive Treatment for l-dopa-induced Involuntary Movements in a Rat Model of Parkinson's Disease.
Yoshiki Murakami, Haruo Nishijima, Takashi Nakamura, Tomonori Furukawa, Iku Kinoshita, Tomoya Kon, Chieko Suzuki, Masahiko Tomiyama
Neuroscience letters 806 137248 - 137248 2023.5
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Effect of Ionizing Radiation on the Intercellular Network of Murine Cerebral Cortical Neurons
Yamaguchi Masaru, Tsujiguchi Takakiyo, Furukawa Tomonori, Shimoyama Shuji, Nakamura Toshiya, Mariya Yasushi, Yamada Junko
Radiation Environment and Medicine 12 ( 1 ) 65 - 73 2023.2
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Pathological substrate of memory impairment in multiple system atrophy.
Yasuo Miki, Kunikazu Tanji, Kana Shinnai, Makoto T Tanaka, Firat Altay, Sandrine C Foti, Catherine Strand, Takanori Sasaki, Tomoya Kon, Shuji Shimoyama, Tomonori Furukawa, Haruo Nishijima, Hiromi Yamazaki, Yasmine T Asi, Conceição Bettencourt, Zane Jaunmuktane, Mari Tada, Fumiaki Mori, Hiroki Mizukami, Masahiko Tomiyama, Hilal A Lashuel, Tammaryn Lashley, Akiyoshi Kakita, Helen Ling, Andrew J Lees, Janice L Holton, Thomas T Warner, Koichi Wakabayashi
Neuropathology and applied neurobiology 48 ( 7 ) e12844 2022.12
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IGF-1を標的とした自閉スペクトラム症治療薬の探索
下山 修司, 古川 智範, 坂本 由唯, 長谷川 敦史, 清水 律子, 小島 宏建, 上野 伸哉, 中村 和彦
日本脳科学会プログラム・抄録集 49回 35 - 35 2022.12
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GABAA受容体の細胞内分布におけるβ3サブユニットのリン酸化の影響
藤井 萌加, 下山 修司, 古川 智範, 上野 伸哉
日本生理学雑誌 84 ( 2 ) 35 - 35 2022.5
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ジアゼパム長期使用による海馬神経機能への影響
増山 望, 古川 智範, 二階堂 義和, 下山 修司, 能登谷 綾香, 上野 伸哉
日本生理学雑誌 84 ( 2 ) 36 - 36 2022.5
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The role of neutrophil gelatinase-associated lipocalin and iron homeostasis in object recognition impairment in aged sepsis-survivor rats.
Yoshikazu Nikaido, Yoko Midorikawa, Tomonori Furukawa, Shuji Shimoyama, Daiki Takekawa, Masato Kitayama, Shinya Ueno, Tetsuya Kushikata, Kazuyoshi Hirota
Scientific reports 12 ( 1 ) 249 - 249 2022.1
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Impaired Cognitive Function and Hippocampal Changes Following Chronic Diazepam Treatment in Middle-Aged Mice.
Tomonori Furukawa, Yoshikazu Nikaido, Shuji Shimoyama, Nozomu Masuyama, Ayaka Notoya, Shinya Ueno
Frontiers in aging neuroscience 13 777404 - 777404 2021.11
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Copy number variations in Japanese children with autism spectrum disorder.
Yui Sakamoto, Shuji Shimoyama, Tomonori Furukawa, Masaki Adachi, Michio Takahashi, Tamaki Mikami, Michito Kuribayashi, Ayako Osato, Daiki Tsushima, Manabu Saito, Shinya Ueno, Kazuhiko Nakamura
Psychiatric genetics 31 ( 3 ) 79 - 87 2021.6
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GABAA Receptors and Maternally Derived Taurine Regulate the Temporal Specification of Progenitors of Excitatory Glutamatergic Neurons in the Mouse Developing Cortex.
Shiro Tochitani, Tomonori Furukawa, Ryo Bando, Shigeaki Kondo, Takashi Ito, Yoshitaka Matsushima, Toshio Kojima, Hideo Matsuzaki, Atsuo Fukuda
Cerebral cortex (New York, N.Y. : 1991) 2021.5
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GABAA Receptors and Maternally Derived Taurine Regulate the Temporal Specification of Progenitors of Excitatory Glutamatergic Neurons in the Mouse Developing Cortex.
Shiro Tochitani, Tomonori Furukawa, Ryo Bando, Shigeaki Kondo, Takashi Ito, Yoshitaka Matsushima, Toshio Kojima, Hideo Matsuzaki, Atsuo Fukuda
Cerebral cortex (New York, N.Y. : 1991) 31 ( 10 ) 4554 - 4575 2021.5
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Lipopolysaccharide induces mouse translocator protein (18 kDa) expression via the AP-1 complex in the microglial cell line, BV-2.
Shuji Shimoyama, Tomonori Furukawa, Yoshiki Ogata, Yoshikazu Nikaido, Kohei Koga, Yui Sakamoto, Shinya Ueno, Kazuhiko Nakamura
PloS one 14 ( 9 ) e0222861 - e0222861 2019.9
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Phospholipase C-related inactive protein type-1 deficiency affects anesthetic electroencephalogram activity induced by propofol and etomidate in mice.
Tomonori Furukawa, Yoshikazu Nikaido, Shuji Shimoyama, Yoshiki Ogata, Tetsuya Kushikata, Kazuyoshi Hirota, Takashi Kanematsu, Masato Hirata, Shinya Ueno
Journal of anesthesia 33 ( 4 ) 531 - 542 2019.8
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Phospholipase C-related inactive protein type-1 deficiency affects anesthetic electroencephalogram activity induced by propofol and etomidate in mice.
Tomonori Furukawa, Yoshikazu Nikaido, Shuji Shimoyama, Yoshiki Ogata, Tetsuya Kushikata, Kazuyoshi Hirota, Takashi Kanematsu, Masato Hirata, Shinya Ueno
Journal of anesthesia 33 ( 4 ) 531 - 542 2019.7
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遺伝子Tspoの発現制御メカニズムの解明
下山 修司, 古川 智範, 小潟 佳輝, 中村 和彦, 上野 伸哉
弘前医学 69 ( 1-4 ) 207 - 207 2019.3
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Lipopolysaccharide induces mouse translocator protein (18 kDa) expression via the AP-1 complex in the microglial cell line, BV-2.
Shuji Shimoyama, Tomonori Furukawa, Yoshiki Ogata, Yoshikazu Nikaido, Kohei Koga, Yui Sakamoto, Shinya Ueno, Kazuhiko Nakamura
PloS one 14 ( 9 ) e0222861 2019
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〈一般演題抄録〉遺伝子<i>Tspo</i> の発現制御メカニズムの解明
下山 修司, 古川 智範, 小潟 佳輝, 中村 和彦, 上野 伸哉
弘前医学 69 ( 1 ) 207 2019
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Anti-hypersensitive effect of angiotensin 1-7 on streptozotocin-induced diabetic neuropathic pain in mice
Ogata Yoshiki, Nemoto Wataru, Yamagata Ryota, Nakagawasai Osamu, Shimoyama Shuji, Furukawa Tomonori, Ueno Shinya, Tan-No Koichi
European Journal of Pain 23 ( 4 ) 739 - 749 2018.11
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Chronic inflammatory pain induced GABAergic synaptic plasticity in the adult mouse anterior cingulate cortex.
Molecular Pain 14 ( 14 ) 1 - 14 2018.6
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MHC Class I in Dopaminergic Neurons Suppresses Relapse to Reward Seeking
Murakami Gen, Edamura Mitsuhiro, Furukawa Tomonori, Kawasaki Hideya, Kosugi Isao, Fukuda Atsuo, Iwashita Toshihide and Nakahara Daiichiro
Science Advances 2018.3
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MHC class I in dopaminergic neurons suppresses relapse to reward seeking.
Murakami G, Edamura M, Furukawa T, Kawasaki H, Kosugi I, Fukuda A, Iwashita T, Nakahara D
Science advances 4 ( 3 ) eaap7388 2018.3
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Propofol Anesthesia Is Reduced in Phospholipase C-Related Inactive Protein Type-1 Knockout Mice.
Nikaido Y, Furukawa T, Shimoyama S, Yamada J, Migita K, Koga K, Kushikata T, Hirota K, Kanematsu T, Hirata M, Ueno S
The Journal of pharmacology and experimental therapeutics 361 ( 3 ) 367 - 374 2017.6
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Propofol Anesthesia Is Reduced in Phospholipase C-Related Inactive Protein Type-1 Knockout Mice.
Nikaido Y, Furukawa T, Shimoyama S, Yamada J, Migita K, Koga K, Kushikata T, Hirota K, Kanematsu T, Hirata M, Ueno S.
J Pharmacol Exp Ther 361 ( 3 ) 367 - 374 2017.4
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Activations of muscarinic M1 receptors in the anterior cingulate cortex contribute to the antinociceptive effect via GABAergic transmission
Kohei Koga, Yu Matsuzaki, Kenji Honda, Fumihiro Eto, Tomonori Furukawa, Keisuke Migita, Keiichi Irie, Kenichi Mishima, Shinya Ueno
Molecular Pain 13 1 - 11 2017.2
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Chronic diazepam administration increases the expression of Lcn2 in the CNS
Tomonori Furukawa, Shuji Shimoyama, Yasuo Miki, Yoshikazu Nikaido, Kohei Koga, Kazuhiko Nakamura, Koichi Wakabayashi, Shinya Ueno
Pharmacology Research & Perspectives 5 ( 1 ) e00283 2017.1
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〈一般演題抄録〉うつ病モデルラットは内側前頭前野機能異常を起こす
二階堂 義和, 古川 智範, 下山 修司, 古賀 浩平, 上野 伸哉
弘前医学 67 ( 2 ) 185 2017
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〈一般演題抄録〉ジアゼパム長期投与マウス脳組織のトランスクリプトーム解析
古川 智範, 下山 修司, 二階堂 義和, 古賀 浩平, 中村 和彦, 上野 伸哉
弘前医学 67 ( 2 ) 186 2017
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〈一般演題抄録〉ジアゼパム長期投与マウスにおける脳内 Lcn2 発現および認知機能の解析
古川 智範, 二階堂 義和, 下山 修司, 三木 康生, 古賀 浩平, 中村 和彦, 若林 孝一, 上野 伸哉
弘前医学 68 ( 1 ) 88 2017
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HSP90 Regulation of P2X7 Receptor Function Requires an Intact Cytoplasmic C-Terminus.
Keisuke Migita, Taku Ozaki, Shuji Shimoyama, Junko Yamada, Yoshikazu Nikaido, Tomonori Furukawa, Yuko Shiba, Terrance M Egan, Shinya Ueno
Molecular pharmacology 90 ( 2 ) 116 - 126 2016.8
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HSP90 Regulation of P2X7 Receptor Function Requires an Intact Cytoplasmic C-Terminus.
Migita K, Ozaki T, Shimoyama S, Yamada J, Nikaido Y, Furukawa T, Shiba Y, Egan TM, Ueno S
Molecular pharmacology 90 ( 2 ) 116 - 26 2016.8
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cis-3-Hexenol and trans-2-hexenal mixture prevents development of PTSD-like phenotype in rats.
Yoshikazu Nikaido, Junko Yamada, Keisuke Migita, Yuko Shiba, Tomonori Furukawa, Toshihiro Nakashima, Shinya Ueno
Behavioural brain research 297 251 - 258 2016.1
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cis-3-Hexenol and trans-2-hexenal mixture prevents development of PTSD-like phenotype in rats.
Nikaido Y, Yamada J, Migita K, Shiba Y, Furukawa T, Nakashima T, Ueno S
Behavioural brain research 297 251 - 8 2016.1
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GABA<sub>A</sub> 受容体応答の制御機構
上野 伸哉, 古川 智範, 二階堂 義和, 下山 修司, 柴 祐子, 山田 順子
弘前医学 66 ( 2 ) 105 - 109 2016
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Activity-dependent endogenous taurine release facilitates excitatory neurotransmission in the neocortical marginal zone of neonatal rats.
Qian T, Chen R, Nakamura M, Furukawa T, Kumada T, Akita T, Kilb W, Luhmann HJ, Nakahara D, Fukuda A
Frontiers in cellular neuroscience 8 33 2014
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Roles of taurine-mediated tonic GABAA receptor activation in the radial migration of neurons in the fetal mouse cerebral cortex.
Furukawa T, Yamada J, Akita T, Matsushima Y, Yanagawa Y, Fukuda A
Frontiers in cellular neuroscience 8 88 2014
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De Novo mutations in GNAO1, encoding a Gαo subunit of heterotrimeric G proteins, cause epileptic encephalopathy.
Nakamura K, Kodera H, Akita T, Shiina M, Kato M, Hoshino H, Terashima H, Osaka H, Nakamura S, Tohyama J, Kumada T, Furukawa T, Iwata S, Shiihara T, Kubota M, Miyatake S, Koshimizu E, Nishiyama K, Nakashima M, Tsurusaki Y, Miyake N, Hayasaka K, Ogata K, Fukuda A, Matsumoto N, Saitsu H
American journal of human genetics 93 ( 3 ) 496 - 505 2013.9
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Cl⁻ homeodynamics in gap junction-coupled astrocytic networks on activation of GABAergic synapses.
Egawa K, Yamada J, Furukawa T, Yanagawa Y, Fukuda A
The Journal of physiology 591 ( 16 ) 3901 - 17 2013.8
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Guidepost neurons for the lateral olfactory tract: expression of metabotropic glutamate receptor 1 and innervation by glutamatergic olfactory bulb axons.
Tatsumi Hirata, Tatsuro Kumada, Takahiko Kawasaki, Tomonori Furukawa, Atsu Aiba, François Conquet, Yumiko Saga, Atsuo Fukuda
Developmental neurobiology 72 ( 12 ) 1559 - 1576 2012.12
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Guidepost neurons for the lateral olfactory tract: expression of metabotropic glutamate receptor 1 and innervation by glutamatergic olfactory bulb axons.
Hirata T, Kumada T, Kawasaki T, Furukawa T, Aiba A, Conquet F, Saga Y, Fukuda A
Developmental neurobiology 72 ( 12 ) 1559 - 76 2012.12
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Taurine inhibits K+-Cl- cotransporter KCC2 to regulate embryonic Cl- homeostasis via with-no-lysine (WNK) protein kinase signaling pathway.
Inoue K, Furukawa T, Kumada T, Yamada J, Wang T, Inoue R, Fukuda A
The Journal of biological chemistry 287 ( 25 ) 20839 - 50 2012.6
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The physiological roles of vesicular GABA transporter during embryonic development: a study using knockout mice.
Saito K, Kakizaki T, Hayashi R, Nishimaru H, Furukawa T, Nakazato Y, Takamori S, Ebihara S, Uematsu M, Mishina M, Miyazaki J, Yokoyama M, Konishi S, Inoue K, Fukuda A, Fukumoto M, Nakamura K, Obata K, Yanagawa Y
Molecular brain 3 40 2010.12
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Low-concentration tributyltin perturbs inhibitory synaptogenesis and induces neuronal death in immature but not mature neurons.
Yamada J, Inoue K, Furukawa T, Fukuda A
Toxicology letters 198 ( 2 ) 282 - 8 2010.10
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GABA imaging in brain slices using immobilized enzyme-linked photoanalysis.
Morishima T, Uematsu M, Furukawa T, Yanagawa Y, Fukuda A, Yoshida S
Neuroscience research 67 ( 4 ) 347 - 53 2010.8
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Dominant-negative mutations in alpha-II spectrin cause West syndrome with severe cerebral hypomyelination, spastic quadriplegia, and developmental delay.
Saitsu H, Tohyama J, Kumada T, Egawa K, Hamada K, Okada I, Mizuguchi T, Osaka H, Miyata R, Furukawa T, Haginoya K, Hoshino H, Goto T, Hachiya Y, Yamagata T, Saitoh S, Nagai T, Nishiyama K, Nishimura A, Miyake N, Komada M, Hayashi K, Hirai S, Ogata K, Kato M, Fukuda A, Matsumoto N
American journal of human genetics 86 ( 6 ) 881 - 91 2010.6
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Molecular basis for the GABAA receptor-mediated tonic inhibition in rat somatosensory cortex.
Yamada J, Furukawa T, Ueno S, Yamamoto S, Fukuda A
Cerebral cortex (New York, N.Y. : 1991) 17 ( 8 ) 1782 - 7 2007.8
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Insertion of alpha7 nicotinic receptors at neocortical layer V GABAergic synapses is induced by a benzodiazepine, midazolam.
Yamamoto S, Yamada J, Ueno S, Kubota H, Furukawa T, Yamamoto S, Fukuda A
Cerebral cortex (New York, N.Y. : 1991) 17 ( 3 ) 653 - 60 2007.3
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GABA-A receptors regulate neocortical neuronal migration in vitro and in vivo.
Heck N, Kilb W, Reiprich P, Kubota H, Furukawa T, Fukuda A, Luhmann HJ
Cerebral cortex (New York, N.Y. : 1991) 17 ( 1 ) 138 - 48 2007.1
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Differential expression of KCC2 accounts for the differential GABA responses between relay and intrinsic neurons in the early postnatal rat olfactory bulb.
Wang C, Ohno K, Furukawa T, Ueki T, Ikeda M, Fukuda A, Sato K
The European journal of neuroscience 21 ( 5 ) 1449 - 55 2005.3
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Brain oxytocin augments stress-induced long-lasting plasma adrenocorticotropic hormone elevation in rats.
Nakashima T, Noguchi T, Furukawa T, Yamasaki M, Makino S, Miyata S, Kiyohara T
Neuroscience letters 321 ( 3 ) 161 - 4 2002.3