Papers - HORIE Kayo
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Stress-reducing effect of laughter in live comedy performance from salivary α-amylase and salivary oxytocin.
Horie K, Nanashima N, In N, Tomisawa T
BMC research notes 18 ( 1 ) 456 2025.10
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Total synthesis of quasi-symmetric dihydrofuran lignans (−)-ribesin A and B isolated from Ribes nigrum leaves
Kae Horio, Hayato Maeda, Kayo Horie, Naoki Nanashima, Ken-ichi Nihei
Tetrahedron 181 134675 2025.8
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Silencing of <i>ERRα</i> gene represses cell proliferation and induces apoptosis in human skin fibroblasts
Naoki Nanashima, Toshio Norikura, Manabu Nakano, Chie Hata, Kayo Horie
Molecular Medicine Reports 31 ( 1 ) 2025.1
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Unlocking optimism in everyday life: a short-term study on the power of live comedy to reduce stress and anxiety in general public.
Tomisawa T, Horie K, In N, Nanashima N, Takamagi S, Mikami K
Health psychology and behavioral medicine 13 ( 1 ) 2493141 2025
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Detecting Phytoestrogens and Mammalian Estrogens in Blackcurrants (Ribes nigrum)
Naoki Nanashima, Kayo Horie, Hayato Maeda, Yoji Kato
Revista Brasileira de Farmacognosia 34 ( 5 ) 1196 - 1199 2024.8
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Blackcurrant extract promotes differentiation of MC3T3‑E1 pre‑osteoblasts.
Naoki Nanashima, Kayo Horie, Indrawati Oey
Biomedical reports 21 ( 2 ) 121 - 121 2024.8
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Exosomal MicroRNA as Biomarkers for Diagnosing or Monitoring the Progression of Ovarian Clear Cell Carcinoma: A Pilot Study
Kayo Horie, Naoki Nanashima, Yoshihito Yokoyama, Haruhiko Yoshioka, Jun Watanabe
Molecules 27 ( 12 ) 3953 - 3953 2022.6
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Morphometrical Differences among Endometrial Endometrioid Carcinoma Grade 1, Grade 3, and Serous Carcinoma in Endometrial Liquid-Based Cytology Preparations.
Odashima H, Yoshioka H, Minami K, Miyakawa K, Horie K, Norimatsu Y, Yanoh K, Watanabe J
Acta cytologica 66 ( 6 ) 524 - 531 2022
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Usefulness of Fractal Analysis of Kirsch Edge Images for the Tissue Fragment Inner Structure in Breast FNAB
Haruhiko Yoshioka, Tsubasa Shimoda, Sota Oikawa, Satoko Morohashi, Yoshie Hasegawa, Kayo Horie, Jun Watanabe
Acta Cytologica 1 - 10 2021.10
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Potential Vasculoprotective Effects of Blackcurrant ( Ribes nigrum) Extract in Diabetic KK-A y Mice
Kayo Horie, Hayato Maeda, Naoki Nanashima and Indrawati Oey
Molecules 26 ( 21 ) 6459 - 6459 2021.10
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子宮内膜LBC法のEGBD間質細胞と類内膜癌G1の核くぼみクラスター分析による核形態解析
南 宏樹, 吉岡 治彦, 小田嶋 広和, 宮川 京大, 堀江 香代, 則松 良明, 矢納 研二, 渡邉 純
日本臨床細胞学会雑誌 60 ( Suppl.2 ) 552 - 552 2021.10
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Hypocholesterolemic Effect of Blackcurrant (Ribes nigrum) Extract in Healthy Female Subjects: A Pilot Study.
Naoki Nanashima, Kayo Horie, Maiko Kitajima, Shizuka Takamagi, Kasumi Mikami, Naoya In, Toshiko Tomisawa
Molecules (Basel, Switzerland) 26 ( 13 ) 2021.7
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Morphological Differences between Liquid-Based Cytology and Conventional Preparation in Endometrial Endometrioid Carcinoma Grade 1 and Grade 3, and the Differentiation of Grades in Each Method.
Hirokazu Odashima, Haruhiko Yoshioka, Kasumi Ota, Yuya Goto, Misuzu Noro, Kayo Horie, Jun Watanabe
Acta cytologica 1 - 8 2021.3
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Blackcurrant (Ribes nigrum L.) Extract Exerts Potential Vasculoprotective Effects in Ovariectomized Rats, Including Prevention of Elastin Degradation and Pathological Vascular Remodeling.
Kayo Horie, Naoki Nanashima, Hayato Maeda, Toshiko Tomisawa, Indrawati Oey
Nutrients 13 ( 2 ) 2021.2
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Exosomes including carbonyl reductase 1 DNA inhibit proliferation of ovarian cancer cells.
Anna Takabayashi-Ebina, Minako Yokoyama, Kayo Horie, and Yoshihito Yokoyama
Hirosaki medical journal 71 120 - 131 2021.1
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Carbonyl reductase 1-overexpressing exosomes inhibit proliferation of ovarian cancer cells
Takabayashi-Ebina Anna, Yokoyama Minako, Horie Kayo, Yokoyama Yoshihito
Hirosaki Medical Journal 71 ( 2 ) 120 - 130 2021
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Fractal Analysis Method for the Complexity of Cell Cluster Staining on Breast FNAB.
Haruhiko Yoshioka, Anna Herai, Sota Oikawa, Satoko Morohashi, Yoshie Hasegawa, Kayo Horie, Jun Watanabe
Acta cytologica 65 ( 1 ) 4 - 12 2021
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Carbonyl reductase 1-overexpressing exosomes inhibit proliferation of ovarian cancer cells
Anna Takabayashi-Ebina, Minako Yokoyama, Kayo Horie, Yoshihito Yokoyama
Hirosaki Medical Journal 71 ( 2-4 ) 120 - 130 2021
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Morphological Differences between Liquid-Based Cytology and Conventional Preparation in Endometrial Endometrioid Carcinoma Grade 1 and Grade 3, and the Differentiation of Grades in Each Method.
Hirokazu Odashima, Haruhiko Yoshioka, Kasumi Ota, Yuya Goto, Misuzu Noro, Kayo Horie, Jun Watanabe
Acta cytologica 65 ( 3 ) 227 - 234 2021
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Outer Cutoff Value for the Box-Counting Method for Fractal Analysis of the Nucleus Using Kirsch Edge Detection.
Haruhiko Yoshioka, Kouki Minami, Hirokazu Odashima, Keita Miyakawa, Kayo Horie, Jun Watanabe
Acta cytologica 65 ( 2 ) 186 - 193 2021
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Outer Cutoff Value for the Box-Counting Method for Fractal Analysis of the Nucleus Using Kirsch Edge Detection.
Haruhiko Yoshioka, Kouki Minami, Hirokazu Odashima, Keita Miyakawa, Kayo Horie, Jun Watanabe
Acta cytologica 65 ( 2 ) 186 - 193 2020.12
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Expression of CA2 and CA9 carbonic anhydrases in ulcerative colitis and ulcerative colitis-associated colorectal cancer.
Norihiro Nakada, Tetuo Mikami, Kayo Horie, Ryo Nagashio, Yasutaka Sakurai, Itaru Sanoyama, Tsutomu Yoshida, Miwa Sada, Kiyonori Kobayashi, Yuichi Sato, Isao Okayasu, Yoshiki Murakumo
Pathology international 70 ( 8 ) 523 - 532 2020.8
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Blackcurrant (Ribes nigrum) Extract Prevents Dyslipidemia and Hepatic Steatosis in Ovariectomized Rats.
*Naoki Nanashima, *Kayo Horie, Kanako Yamanouchi, Toshiko Tomisawa, Maiko Kitajima, Indrawati Oey, Hayato Maeda *equally contributed
Nutrients 12 ( 5 ) 2020.5
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Morphological analysis of peritoneal dissemination of ovarian cancer based on levels of carbonyl reductase 1 expression
Fumie Oyama, Yoshiya Asano, Hiroshi Shimoda, Kayo Horie, Jun Watanabe, Yoshihito Yokoayama
European Journal of Gynaecological Oncology 41 ( 3 ) 352 - 360 2020.3
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Bmi-1 Immunohistochemical Expression in Endometrial Carcinoma is Correlated with Prognostic Activity.
Kayo Horie, Chihiro Iseki, Moe Kikuchi, Keita Miyakawa, Mao Yoshizaki, Haruhiko Yoshioka, Jun Watanabe
Medicina (Kaunas, Lithuania) 56 ( 2 ) 2020.2
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Effects of Blackcurrant Anthocyanin on Endothelial Function and Peripheral Temperature in Young Smokers.
Toshiko Tomisawa, Naoki Nanashima, Maiko Kitajima, Kasumi Mikami, Shizuka Takamagi, Hayato Maeda, Kayo Horie, Fu-Chih Lai, Tomohiro Osanai
Molecules (Basel, Switzerland) 24 ( 23 ) 2019.11
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Establishment of nuclear grade evaluation method for endometrial endometrioid carcinoma, and the significance of separately evaluating nuclear atypia of the glandular and solid structure parts
Haruhiko Yoshioka,Miho Iwaya ,Kayo Horie,Yoshihito Yokoyama,Jun Watanabe
Archives of Cytology and Histopathology Research (ACHR) 4 ( 3 ) 220 - 227 2019.10
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Cyclin A is a reliable proliferation marker in endometrial cancer cell lines.
Kayo Horie, Hayate Yamamoto, Kouhei Karube, Kai Takebayashi, Hironori Yoshino, Haruhiko Yoshioka, Jun Watanabe
Oncology letters 17 ( 5 ) 4455 - 4462 2019.5
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Blackcurrant Extract with Phytoestrogen Activity Alleviates Hair Loss in Ovariectomized Rats.
*Naoki Nanashima, *Kayo Horie *equally contributed
Molecules (Basel, Switzerland) 24 ( 7 ) 2019.4
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Phytoestrogenic Effects of Blackcurrant Anthocyanins Increased Endothelial Nitric Oxide Synthase (eNOS) Expression in Human Endothelial Cells and Ovariectomized Rats.
Kayo Horie, Naoki Nanashima, Hayato Maeda
Molecules (Basel, Switzerland) 24 ( 7 ) 2019.3
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Usefulness of Cytological Scoring Method by Breast Fine Needle Aspiration Cytology on Breast Duct Dilatation and Cystic Lesions.
Haruhiko Yoshioka, Hiroki Ueno, Souta Oikawa, Masanori Tanaka, Yoshie Hasegawa, Kayo Horie, Jun Watanabe
Journal of cytology 36 ( 1 ) 53 - 58 2019.1
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子宮内膜癌細胞株（Ishikawa細胞)におけるestrogen receptor(ER)遺伝子導入及びエストロゲン作用の検討
堀江 香代, 藤田大貴, 三浦文仁, 金丸絋弓, 吉岡 治彦, 渡邉 純
青森県臨床細胞学会雑誌 ( 35 ) 35 - 41 2018.12
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Adobe Photoshopを用いた細胞診画像の半自動領域分割法の信頼性検証
吉岡 治彦, 吾妻優子, 佐々木宗矩, 田崎里奈, 津島愛, 野月雅実, 山本颯, 吉崎真央, 堀江香代, 渡邉 純
青森県臨床細胞学会雑誌 ( 第35号 ) 28 - 34 2018.12
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カシスの魅力と健康機能性
前多 隼人, 西山 広亮, 小舘 めい, 福田 覚, 七島 直樹, 堀江 香代, 冨澤 登志子, 藤田 俊文, 北島 麻衣子, 加藤 陽治
New food industry = ニューフードインダストリー : 食品加工および資材の新知識 60 ( 9 ) 11 - 18 2018.9
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Blackcurrant Anthocyanins Increase the Levels of Collagen, Elastin, and Hyaluronic Acid in Human Skin Fibroblasts and Ovariectomized Rats.
Naoki Nanashima, Kayo Horie, Hayato Maeda, Toshiko Tomisawa, Maiko Kitajima, Toshiya Nakamura
Nutrients 10 ( 4 ) 2018.4
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Peroxiredoxin 1 expression in active ulcerative colitis mucosa identified by proteome analysis and involvement of thioredoxin based on immunohistochemistry.
Kayo Horie, Tetuo Mikami, Tsutomu Yoshida, Yuichi Sato, Isao Okayasu
Oncology letters 15 ( 2 ) 2364 - 2372 2018.2
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WSI(バーチャルスライド）を併用した臨床検査技師教育
鷲谷清忠、吉岡治彦、堀江香代、渡邉純
medical technology 45 ( 12 ) 1255 - 1260 2018
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Phytoestrogenic Activity of Blackcurrant Anthocyanins Is Partially Mediated through Estrogen Receptor Beta.
Naoki Nanashima, Kayo Horie, Hayato Maeda
Molecules (Basel, Switzerland) 23 ( 1 ) 2017.12
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Anthocyanin‑rich blackcurrant extract inhibits proliferation of the MCF10A healthy human breast epithelial cell line through induction of G0/G1 arrest and apoptosis.
Naoki Nanashima, Kayo Horie, Mitsuru Chiba, Manabu Nakano, Hayato Maeda, Toshiya Nakamura
Molecular medicine reports 16 ( 5 ) 6134 - 6141 2017.11
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Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness.
Naoki Nanashima, Kayo Horie, Toshiyuki Yamada, Takeshi Shimizu, Shigeki Tsuchida
Oncology reports 37 ( 5 ) 2964 - 2970 2017.5
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子宮頸部LBC標本における核・クロマチンの粒子解析によるクラスター分類を用いた化生と中等度異形成の鑑別
林崎歩美、吉岡治彦、熊谷直哉、小島啓子、黒瀬 顕、二神真行、横山良仁 、堀江香代、渡邉 純
日本臨床検査学教育学会, 臨床検査学教育 10 ( 1 ) 132 - 133 2017.3
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Comparison of cell microscopy images and image analysis for the purpose of improving the accuracy of endometrial liquid-based cytology (LBC)
HORIE Kayo, GOTO Yuya, NORO Misuzu, YOSHIOKA Haruhiko, TONE Kiyoshi, KOJIMA Keiko, YOKOYAMA Yoshihito, WATANABE Jun
Japanese Journal of Medical Technology 66 ( 2 ) 103 - 109 2017
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FOXP1 forkhead transcription factor is associated with the pathogenesis of endometrial cancer.
Makito Mizunuma, Yoshihito Yokoyama, Masayuki Futagami, Kayo Horie, Jun Watanabe, Hideki Mizunuma
Heliyon 2 ( 5 ) e00116 - e00116 2016.5
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Phytoestrogenic activity of blackcurrant (Ribes nigrum) anthocyanins is mediated through estrogen receptor alpha.
Naoki Nanashima, Kayo Horie, Toshiko Tomisawa, Mitsuru Chiba, Manabu Nakano, Toshifumi Fujita, Hayato Maeda, Maiko Kitajima, Shizuka Takamagi, Daishi Uchiyama, Jun Watanabe, Toshiya Nakamura, Yoji Kato
Molecular nutrition & food research 59 ( 12 ) 2419 - 2431 2015.10
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Usefulness of Evaluation of Nuclear Color by Visible-Microscopic Spectroscopy for Objective Differentiation between Non-Cancer and Cancer Cells Prepared Using Liquid-Based Cytology
Yoshioka, H., Hoshiai, K., Nakamura, T., Horie, K., Washiya, k.,Watanabe, J.
J Cytol Histol 6 308 2015
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Evaluation of Endometrial Endometrioid Carcinoma Grade using Ultraviolet-Visible Light Microscopic Spectroscopy.
Yoshioka, H., Kondo, H., Horie, K., Washiya, k.,Watanabe, J.
J Cytol Histol 6 ( (6) ) 381 2015
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Total cellular glycomics allows characterizing cells and streamlining the discovery process for cellular biomarkers.
*Naoki Fujitani, *Jun-ichi Furukawa,* Kayo Araki(Horie), Tsuyoshi Fujioka, Yasuhiro Takegawa, Jinhua Piao, Taiki Nishioka, Tomohiro Tamura, Toshio Nikaido, Makoto Ito, Yukio Nakamura, Yasuro Shinohara *equally contributed
PNAS 110 ( 6 ) 2105 - 2110 2013.2
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Total cellular glycomics allows characterizing cells and streamlining the discovery process for cellular biomarkers.
Naoki Fujitani, Jun-ichi Furukawa, Kayo Horie(Araki),, Tsuyoshi Fujioka, Yasuhiro Takegawa, Jinhua Piao, Taiki Nishioka, Tomohiro Tamura, Toshio Nikaido, Makoto Ito, Yukio Nakamura, Yasuro Shinohara
Proceedings of the National Academy of Sciences of the United States of America 110 ( 6 ) 2105 - 10 2013.2
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Simultaneous analysis of heparan sulfate, chondroitin/dermatan sulfates, and hyaluronan disaccharides by glycoblotting-assisted sample preparation followed by single-step zwitter-ionic-hydrophilic interaction chromatography.
Yasuhiro Takegawa, Kayo Araki(Horie), Naoki Fujitani, Jun-ichi Furukawa, Hiroaki Sugiyama, Hideaki Sakai, Yasuro Shinohara
Analytical chemistry 83 ( 24 ) 9443 - 9449 2011.12
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Qualitative and quantitative cellular glycomics of glycosphingolipids based on rhodococcal endoglycosylceramidase-assisted glycan cleavage, glycoblotting-assisted sample preparation, and matrix-assisted laser desorption ionization tandem time-of-flight mass spectrometry analysis.
Naoki Fujitani, Yasuhiro Takegawa, Yohei Ishibashi, Kayo Araki(Horie), Jun-ichi Furukawa, Susumu Mitsutake, Yasuyuki Igarashi, Makoto Ito, Yasuro Shinohara
The Journal of biological chemistry 286 ( 48 ) 41669 - 41679 2011.12
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A versatile method for analysis of serine/threonine posttranslational modifications by β-elimination in the presence of pyrazolone analogues.
Jun-ichi Furukawa, Naoki Fujitani, Kayo Horie(Araki),Yasuhiro Takegawa, Kota Kodama, Yasuro Shinohara
Analytical chemistry 83 ( 23 ) 9060 - 7 2011.12
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Invasive behavior of ulcerative colitis-associated carcinoma is related to reduced expression of CD44 extracellular domain: comparison with sporadic colon carcinoma.
Tetuo Mikami, Tsutomu Yoshida, Yoshiko Numata, Masaomi Kikuchi, Kayo Araki(Horie), Norihiro Nakada, Isao Okayasu
Diagnostic pathology 6 30 - 30 2011.4
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Mucosal remodeling in long-standing ulcerative colitis with colorectal neoplasia: significant alterations of NCAM+ or alpha-SMA+ subepithelial myofibroblasts and interstitial cells.
Isao Okayasu, Tsutomu Yoshida, Tetuo Mikami, Kiyomi Hana, Masashi Yokozawa, Kayo Horie(Araki),Jun Mitsuhashi, Masaomi Kikuchi, Eijiro Adachi, Miwa Sada
Pathology international 59 ( 10 ) 701 - 11 2009.10
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High expression of HSP47 in ulcerative colitis-associated carcinomas: proteomic approach
K Horie(Araki), T Mikami, T Yoshida, M Kikuchi, Y Sato, M Oh-ishi, Y Kodera, T Maeda, I Okayasu
British Journal of Cancer 101 ( 3 ) 492 - 497 2009.8
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High Ki67, Bax, and thymidylate synthase expression well correlates with response to chemoradiation therapy in locally advanced rectal cancers: proposal of a logistic model for prediction.
M Kikuchi, T Mikami, T Sato, W Tokuyama, K Araki(Horie), M Watanabe, K Saigenji, I Okayasu
British journal of cancer 101 ( 1 ) 116 - 123 2009.7
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Appearance of epithelial and stromal genomic instability in background colorectal mucosa of sporadic colorectal cancer patients: relation to age and gender.
Harue Umeto, Tsutomu Yoshida, Kayo Horie(Araki), Hiroko Yagishita, Tetuo Mikami, Isao Okayasu
Journal of gastroenterology 44 ( 10 ) 1036 - 45 2009
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Low frequency of promoter methylation of O6-methylguanine DNA methyltransferase and hMLH1 in ulcerative colitis-associated tumors: comparison with sporadic colonic tumors.
Tetuo Mikami, Tsutomu Yoshida, Yoshiko Numata, Hiroaki Shiraishi, Kayo Horie(Araki), Marie-Christine Guiot, Jeremy R Jass, Isao Okayasu
American journal of clinical pathology 127 ( 3 ) 366 - 73 2007.3
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Fine-needle aspiration cytology of breast lesions: a review of cytological analysis using smooth muscle actin (SMA) immunostaining.
Sakiyo Sato, Hiroshi Kijima, Akihiko Suto, Hiromi Yoshida, Tadamitsu Sato, Masumi Shimbori, Yasuko Terasaki-Fukuzawa, Noboru Onoda, Kayo Araki(Horie), Kazunori Tsuruno, Toshio Takeshita
Anticancer research 23 ( 5b ) 4175 - 4179 2003.9