The Cell Line-Dependent Diversity in Initial Morphological Dynamics of Pancreatic Cancer Cell Peritoneal Metastasis Visualized by an Artificial Human Peritoneal Model

Odagiri T, Asano Y, Kagiya T, Matsusaki M, Akashi M, Shimoda H, Hakamada K.

journal of surgical research   261   351 - 360   2021.1

In Vitro Evaluation System of Pharmacokinetics and Irradiation Effect in Boron Neutron Capture Therapy (BNCT) Using Three-Dimensional Artificial Human Tumor Tissue Model

Shintaro Ishiyama, Yoshiya Asano, Minoru Suzuki, Mitsuru Akashi, Hiroshi Shimoda

Journal of Cancer Therapy   10   835 - 845   2019.10

Inhibitory effect of carbonyl reductase 1 against peritoneal progression of ovarian cancer: Evaluation by ex-vivo 3D-human peritoneal model

Hiroe Oikiri, Yoshiya Asano, Michiya Matsusaki, Mitsuru Akashi, Hiroshi Shimoda, Yoshihito Yokoyama

Molecular Biology Reports   in press   2019.3

〈一般演題抄録〉人工ヒト腹膜組織を用いた Carbonyl reductase 1 による卵巣癌腹膜播種抑制効果の形態学的解析

追切 裕江, 浅野 義哉, 下田 浩, 横山 良仁

弘前医学   69 ( 1-4 )   202   2019.3

Morphological analysis of peritoneal dissemination of ovarian cancer based on levels of carbonyl reductase 1 expression

Fumie Oyama, Yoshiya Asano, Hiroshi Shimoda, Kayo Horie, Jun Watanabe, Yoshihito Yokoyama

European Journal of Gynaecological Oncology   in press   144 - 155   2019.1

In vitro 3D blood/lymph-vascularized human stromal tissues for preclinical assays of cancer metastasis

Nishiguchi A, Matsusaki M, Kano MR, Nishihara H, Okano D, Asano Y, Shimoda H, Kishimoto S, Iwai S, Akashi M.

Biomaterials   179   144 - 155   2018.10

Transplantation of artificial human lymphatic vascular tissues fabricated using a cell-accumulation technique and their engraftment in mouse tissue with vascular remodelling

Asano Y, Shimoda H, Matsusaki M, Akashi M

J Tissue Eng Regen Med   12 ( 3 )   e1501 - e1510   2017.12

Construction of artificial human peritoneal tissue by cell-accumulation technique and its application for visualizing morphological dynamics of cancer peritoneal metastasis

Asano Y, Odagiri T, Oikiri H, Matsusaki M, Akashi M, Shimoda H

Biochem Biophys Res Commun   949 ( 1-2 )   213 - 219   2017.10

Transplantation of three-dimensional artificial human vascular tissues fabricated using an extracellular matrix nanofilm-based cell-accumulation technique

Asano Y, Shimoda H, Okano D, Matsusaki M, Akashi M

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE   11 ( 4 )   1303 - 1307   2017.1

Suppression of starvation-induced autophagy by recombinant toxic shock syndrome toxin-1 in epithelial cells

Asano K, Asano Y, Ono HK, Nakane A

PLoS One   9 ( 11 )   e113018   2014.11

Differentiation of mouse induced pluripotent stem cells into alveolar epithelial cells in vitro for use in vivo

Zhou Q, Ye X, Sun R, Matsumoto Y, Moriyama M, Asano Y, Ajioka Y, Saijo Y

Stem cells translational medicine   3 ( 6 )   675 - 685   2014.6

Effects of angiogenic factors and 3D-microenvironments on vascularization within sandwich cultures.

Akihiro Nishiguchi, Michiya Matsusaki, Yoshiya Asano, Hiroshi Shimoda, Mitsuru Akashi

Biomaterials   35 ( 17 )   4739 - 4748   2014.3

Ultrastructure of blood and lymphatic vascular networks in three-dimensional cultured tissues fabricated by extracellular matrix nanofilm-based cell accumulation technique.

Yoshiya Asano, Akihiro Nishiguchi, Michiya Matsusaki, Daisuke Okano, Erina Saito, Mitsuru Akashi, Hiroshi Shimoda

Microscopy (Oxford, England)   63 ( 3 )   219 - 226   2014.2

Three-dimensional multilayers of smooth muscle cells as a new experimental model for vascular elastic fiber formation studies

Ishiwata R, Yokoyama U, Matsusaki M, Asano Y, Kadowaki K, Ichikawa Y, Umemura M, Fujita T, Minamisawa S, Shimoda H, Akashi M, Ishikawa Y.

Atherosclerosis   233 ( 2 )   590 - 600   2014.1

Mice with Disrupted TGF beta Signaling Have Normal Cerebella Development, but Exhibit Facial Dysmorphogenesis and Strain-Dependent Deficits in Their Body Wall

Yoshiya Asano, Kyoko Koishi, Tony Frugier, Ian S. McLennan

CELLULAR AND MOLECULAR NEUROBIOLOGY   29 ( 5 )   621 - 633   2009.7

Mice with disrupted TGFbeta signaling have normal cerebella development, but exhibit facial dysmorphogenesis and strain-dependent deficits in their body wall (共著)

Asano Y, Koishi K, Frugier T, McLennan IS.

Cellular and molecular neurobiology   29 ( 5 )   621 - 33   2009.2

Nonheme-iron deposition in the hypothalamo-neurohypophyseal system of the rat brain

Li C, Odagiri S, Meguro R, Asano Y, Shoumura K

60   63 - 76   2009.1

Cellular and subcellular localizations of nonheme ferric and ferrous iron in the rat brain: a light and electron microscopic study by the perfusion-Perls and -Turnbull methods (共著)

Meguro R, Asano Y, Odagiri S, Li C, Shoumura K.

Archives of histology and cytology   71 ( 4 )   205 - 222   2008.12

Cellular and subcellular localizations of nonheme ferric and ferrous iron in the rat brain: a light and electron microscopic study by the perfusion-Perls and -Turnbull methods.

Reiko Meguro, Yoshiya Asano, Saori Odagiri, Chengtai Li, Kazuhiko Shoumura

Archives of histology and cytology   71 ( 4 )   205 - 22   2008.12

Chelatable Fe (II) is generated in the rat kidneys exposed to ischemia and reperfusion, and a divalent metal chelator, 2, 2'-dipyridyl, attenuates the acute ischemia/reperfusion-injury of the kidneys: a histochemical study by the perfusion-Perls and -Turnbull methods (共著)

Iwatsuki H, Meguro R, Asano Y, Odagiri S, Li C, Shoumura K.

Archives of histology and cytology   71 ( 2 )   101 - 114   2008.9

Chelatable Fe (II) is generated in the rat kidneys exposed to ischemia and reperfusion, and a divalent metal chelator, 2, 2'-dipyridyl, attenuates the acute ischemia/reperfusion-injury of the kidneys: a histochemical study by the perfusion-Perls and -Turnbull methods.

Hiroyasu Iwatsuki, Reiko Meguro, Yoshiya Asano, Saori Odagiri, Chengtai Li, Kazuhiko Shoumura

Archives of histology and cytology   71 ( 2 )   101 - 14   2008.9

Nonheme-iron histochemistry for light and electron microscopy: a historical, theoretical and technical review.

Reiko Meguro, Yoshiya Asano, Saori Odagiri, Chengtai Li, Hiroyasu Iwatsuki, Kazuhiko Shoumura

Archives of histology and cytology   70 ( 1 )   1 - 19   2007.4

Visualization of non-heme ferric and ferrous iron by highly sensitive non-heme iron histochemistry in the stress-induced acute gastric lesions in the rat.

Asano Y, Meguro R, Odagiri S, Li C, Iwatsuki H, Shoumura K.

Histochemistry and cell biology   125 ( 5 )   515 - 525   2006.4

The presence of ferric and ferrous iron in the nonheme iron store of resident macrophages in different tissues and organs: histochemical demonstrations by the perfusion-Perls and -Turnbull methods in the rat.(共著)

Meguro R, Asano Y, Odagiri S, Li C, Iwatsuki H, Shoumura K.

Archives of histology and cytology   68 ( 3 )   171 - 83   2005.11

The presence of ferric and ferrous iron in the nonheme iron store of resident macrophages in different tissues and organs: histochemical demonstrations by the perfusion-Perls and -Turnbull methods in the rat.

Reiko Meguro, Yoshiya Asano, Saori Odagiri, Chengtai Li, Hiroyasu Iwatsuki, Kazuhiko Shoumura

Archives of histology and cytology   68 ( 3 )   171 - 83   2005.9

Perfusion-Perls and -Turnbull methods supplemented by DAB intensification for nonheme iron histochemistry: demonstration of the superior sensitivity of the methods in the liver, spleen, and stomach of the rat. (共著)

Meguro R, Asano Y, Iwatsuki H, Shoumura K

Histochemistry and cell biology   120 ( 1 )   73 - 82   2003.7

Perfusion-Perls and -Turnbull methods supplemented by DAB intensification for nonheme iron histochemistry: demonstration of the superior sensitivity of the methods in the liver, spleen, and stomach of the rat.

Reiko Meguro, Yoshiya Asano, Hiroyasu Iwatsuki, Kazuhiko Shoumura

Histochemistry and cell biology   120 ( 1 )   73 - 82   2003.7

Changes in non-heme iron histochemistry in the ischemic brains of cats and Mongolian gerbils

H Iwatsuki, R Meguro, Y Asano, K Shoumura

ADVANCES IN BRAIN RESEARCH: CEREBROVASCULAR DISORDERS AND NEURODEGENERATION   1251   87 - 94   2003

Nonheme ferric and ferrous iron accumulation in macrophages of rats and cats

R Meguro, Y Asano, K Shoumura

ADVANCES IN BRAIN RESEARCH: CEREBROVASCULAR DISORDERS AND NEURODEGENERATION   1251   95 - 104   2003

Monoclonal antibody to stage-specific fetal brain 68-kDa glycoprotein (FGP68) revealed increased FGP68 expression in human primary brain tumors.

Shinsuke Kato, Takao Shinozawa, Hiroaki Nagashige, Miyuki Nakamura, Yoshiya Asano, Miki Takikawa, Masako Kato, Akira Awaya, Asao Hirano, Eisaku Ohama

Acta neuropathologica   104 ( 1 )   57 - 66   2002.7

Monoclonal antibody to stage-specific fetal brain 68-kDa glycoprotein (FGP68) revealed increased FGP68 expression in human primary brain tumors.(共著)

Kato S, Shinozawa T, Nagashige H, Nakamura M, Asano Y, Takikawa M, Kato M, Awaya A, Hirano A, Ohama E.

Acta neuropathologica   104 ( 1 )   57 - 66   2002.6

Changes in non-heme iron histochemistry in the ischemic brains of cat and Mongolian gerbiles (共著)

Iwatsuki H, Meguro R, Asano Y, Shoumura K

International Congress Series   1251   87 - 94   2002.2

Flagellin as a biomarker for Bacillus subtilis strains; application to the DB9011 strain and the study of interspecific diversity in amino-acid sequences.

Asano Y, Onishi H, Tajima K, Shinozawa T.

Bioscience, biotechnology, and biochemistry   65 ( 5 )   1218 - 1222   2001.5

Studies on the intestine of Tubellaria I. Production of intestine-specific monoclonal antibody and interspecific cross-reaction.

Asano, Y., Yoshida, A., Isozaki, N., and Ishida, S.

Belgian Journal of Zoology   131 ( suppl. 1 )   137 - 141   2001.4

Production of intestine-specific monoclonal antibody and interspecific cross-reaction in triclads and polyclads

Y Asano, A Yoshida, N Isozaki, S Ishida

BELGIAN JOURNAL OF ZOOLOGY   131 ( suppl.1 )   137 - 141   2001.4

Detection of truncated midkine in Wilms' tumor by a monoclonal antibody against human recombinant truncated midkine.(共著)

Paul S, Mitsumoto T, Asano Y, Kato S, Kato M, Shinozawa T.

Cancer letters   163 ( 2 )   245 - 251   2001.2

Detection of truncated midkine in Wilms' tumor by a monoclonal antibody against human recombinant truncated midkine

S Paul, T Mitsumoto, Y Asano, S Kato, M Kato, T Shinozawa

CANCER LETTERS   163 ( 2 )   245 - 251   2001.2

Establishment of monoclonal antibodies specific for Bacillus subtilis DB9011.

Asano Y, Akaishi E, Tajima K, Shinozawa T.

Bioscience, biotechnology, and biochemistry   64 ( 3 )   652 - 656   2000.3

Monoclonal antibody to human midkine reveals increased midkine expression in human brain tumors.(共著)

Kato S, Ishihara K, Shinozawa T, Yamaguchi H, Asano Y, Saito M, Kato M, Terada T, Awaya A, Hirano A, Dickson DW, Yen SH, Ohama E.

Journal of neuropathology and experimental neurology   58 ( 5 )   430 - 441   1999.5

Monoclonal antibody to human midkine reveals increased midkine expression in human brain tumors

S Kato, K Ishihara, T Shinozawa, H Yamaguchi, Y Asano, M Saito, M Kato, T Terada, A Awaya, A Hirano, DW Dickson, SH Yen, E Ohama

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY   58 ( 5 )   430 - 441   1999.5

Rhodopsin-like proteins in planarian eye and auricle: detection and functional analysis

Asano Y, et al

The Journal of experimental biology   201   1263 - 1271   1998.5

Rhodopsin-like proteins in planarian eye and auricle: detection and functional analysis

Yoshiya Asano, Satoshi Nakamura, Sachiko Ishida, Katsu Azuma, Takao Shinozawa

The Journal of experimental biology   201 (Pt 9)   1263 - 71   1998.5

ヒト肝十二指腸間膜におけるリンパ管システムの解明

鍵谷卓司, 小田切理, 三橋佑人, 渡邉誠二, 成田大一, 浅野義哉, 齊藤絵里奈, 岡野大輔, 袴田健一, 下田浩, 下田浩

日本解剖学会総会・全国学術集会講演プログラム・抄録集   123rd   2018

マイクロファイバーコラーゲンを用いた人工三次元リンパ管組織の構築と構造解析

高橋一人, 渡邉誠二, 成田大一, 浅野義哉, 齊藤絵里奈, 岡野大輔, 松崎典弥, 下田浩, 下田浩

リンパ学   41 ( Supplement )   2018

ヒトVater乳頭部におけるリンパ管システムの解明

鍵谷卓司, 小田切理, 渡邉誠二, 成田大一, 浅野義哉, 齊藤絵里奈, 岡野大輔, 袴田健一, 下田浩, 下田浩

リンパ学   40 ( Supplement )   2017

小型魚類がん転移モデルの作製

齊藤絵里奈, 渡辺誠二, 浅野義哉, 岡野大輔, 成田大一, 磯貝純夫, 下田浩, 下田浩

日本解剖学会総会・全国学術集会講演プログラム・抄録集   122nd   2017

三次元培養組織を用いたヒトリンパ管ネットワーク形成のライブイメージング

岡野大輔, 吉松康裕, 松崎典弥, 浅野義哉, 渡邉誠二, 齊藤絵里奈, 成田大一, 明石満, 渡部徹郎, 下田浩, 下田浩

日本解剖学会総会・全国学術集会講演プログラム・抄録集   122nd   2017

ヒト十二指腸乳頭部におけるリンパ管ネットワークの解明

鍵谷卓司, 小田切理, 渡邉誠二, 成田大一, 浅野義哉, 齊藤絵里奈, 岡野大輔, 袴田健一, 下田浩, 下田浩

日本解剖学会総会・全国学術集会講演プログラム・抄録集   122nd   2017

ヒト・ラットにおけるリンパ管壁細胞の特徴

千葉智博, 成田大一, 渡邉誠二, 浅野義哉, 齊藤絵里奈, 岡野大輔, 下田浩, 下田浩

リンパ学   40 ( Supplement )   2017

Engineering and transplantation of three-dimensional artificial human blood and lymphatic vascular tissues fabricated using cell-accumulation method

Yoshiya Asano, Michiya Matsusaki, Daisuke Okano, Akihiro Nishiguchi, Mitsuru Akashi, Hiroshi Shimoda

Japanese Journal of Lymphology   39 ( 1 )   18 - 20   2016.6

血管・リンパ管ネットワークを有する三次元人工腹膜組織

浅野義哉, 松崎典弥, 明石満, 下田浩

化学工業   66 ( 11 )   824 - 830   2015.11

個体・系統発生における肺血管の形態学的特徴

成田 大一, 齊藤 絵里奈, 磯貝 純夫, 岡野 大輔, 浅野 義哉, 下田 浩

日本組織細胞化学会総会・学術集会講演プログラム・予稿集   55回   98 - 98   2014.9

小型魚類の血管・リンパ管系の構築とがん移植モデルの確立

下田 浩, 齊藤 絵里奈, 渡邉 誠二, 浅野 義哉, 谷 利樹, 成田 大一, 岡野 大輔, 外崎 敬和

弘前医学   65 ( 1 )   116 - 116   2014.4

P-33 小型魚類リンパ管の機能形態学的解析((1)循環器・硬組織関連領域,第3グループ,ポスター発表,第55回日本組織細胞化学会総会・学術集会 第11回日中合同組織細胞化学セミナー)

齊藤 絵里奈, 出口 友則, 磯貝 純夫, 成田 大一, 岡野 大輔, 浅野 義哉, 下田 浩

日本組織細胞化学会総会プログラムおよび抄録集   ( 55 )   99 - 99   2014

小型魚類リンパ管の組織化学的解析

齊藤絵里奈, 出口友則, 磯貝純夫, 成田大一, 岡野大輔, 浅野義哉, 下田浩

日本解剖学会総会・全国学術集会講演プログラム・抄録集   119th   2014

小型魚類リンパ管の機能形態学的解析

齊藤絵里奈, 出口友則, 磯貝純夫, 成田大一, 岡野大輔, 浅野義哉, 下田浩, 下田浩

日本組織細胞化学会総会・学術集会講演プログラム・予稿集   55th   99 - 99   2014

三次元積層培養法で作製したヒト培養組織における脈管ネットワークの微細構造解析

浅野 義哉, 松崎 典弥, 西口 昭広, 齊藤 絵里奈, 岡野 大輔, 明石 満, 下田 浩

日本組織細胞化学会総会・学術集会講演プログラム・予稿集   54回   77 - 77   2013.9

マウスiPS細胞における肺上皮細胞への分化誘導

XHOU Qiliang, YE Xulu, SUN Ruowen, 松本吉史, 浅野義哉, 西條康夫

再生医療   12   2013

小型魚類におけるリンパ管の発生過程と機能形態

齊藤絵里奈, 磯貝純夫, 出口友則, 成田大一, 浅野義哉, 下田浩, 下田浩

日本組織細胞化学会総会・学術集会講演プログラム・予稿集   54th   76 - 76   2013

マウス辺縁新皮質の構造と発生 哺乳類大脳皮質の多層化機構解明への糸口

浅野 義哉, 目黒 玲子, 小田桐 紗織, 一戸 紀孝

解剖学雑誌   85 ( Suppl. )   164 - 164   2010.3

新世界ザル・コモンマーモセットの下側頭葉への入力

目黒 玲子, 小田桐 沙織, 西家 由里子, 星野 真理, 浅野 義哉, 谷 利樹, 一戸 紀孝

解剖学雑誌   85 ( Suppl. )   192 - 192   2010.3

視床前核からラット後部帯状回へ投射する単一軸索の解析

小田桐 紗織, 目黒 玲子, 浅野 義哉, 一戸 紀孝

解剖学雑誌   85 ( Suppl. )   167 - 167   2010.3

5月齢(young adult)と14月齢(middle aged)ラットの脳内非ヘム鉄局在と加齢変化

目黒玲子, 浅野義哉, 小田桐紗織, 李成泰, 正村和彦

解剖学雑誌   83 ( 1 )   18 - 18   2008

ラット中枢神経系における鉄陽性ニューロン及びグリアの光顕及び電顕的観察

目黒 玲子, 浅野 義哉, 小田桐 紗織, 李 成泰, 正村 和彦

解剖学雑誌   82 ( 2 )   75 - 75   2007.6

Nonheme-iron histochemistry for light and electron microscopy: a historical, theoretical and technical review.(共著)

Meguro R, Asano Y, Odagiri S, Li C, Iwatsuki H, Shoumura K.

Archives of histology and cytology   70 ( 1 )   1 - 19   2007.4

In situ非ヘム鉄組織化学により可視化した、マウス脳室上衣及び上衣下における非ヘム鉄の分布

浅野 義哉, 目黒 玲子, 小田桐 紗織, 李 成泰, 正村 和彦

解剖学雑誌   82 ( Suppl. )   215 - 215   2007.3

ラット腎の虚血/再灌流における非ヘム2価鉄の組織化学

岩月 宏泰, 目黒 玲子, 浅野 義哉, 正村 和彦

解剖学雑誌   81 ( 2 )   71 - 71   2006.6

広範囲の組織におけるマクロファージの非ヘム鉄の貯蔵についての組織化学的証明

目黒玲子, 浅野義哉, 小田桐紗織, 李成康, 正村和彦

弘前医学   56 ( 2/4 )   94 - 94   2005

ラット壁細胞の非ヘム鉄とストレス性胃粘膜傷害の関わり

浅野 義哉, 目黒 玲子, 正村 和彦

弘前医学   55 ( 3〜4 )   125 - 125   2004.3

灌流パールス法・灌流タンブル法及びDAB増感によるラット肝・脾・胃の非ヘム鉄組織化学

目黒 玲子, 浅野 義哉, 正村 和彦

弘前医学   55 ( 2 )   80 - 80   2004.1

ラットのマクロファージにおける非ヘム二価鉄及び非ヘム三価鉄蓄積の機能的意義

目黒 玲子, 浅野 義哉, 正村 和彦

解剖学雑誌   78 ( Suppl. )   254 - 254   2003.4

ラットのマクロファージにおける非ヘムニ価鉄及び非ヘム三価鉄蓄積の機能的意義

目黒玲子, 浅野義哉, 正村和彦

解剖学雑誌   78 ( Supplement )   2003