TMEM2 suppresses TLR3-mediated IFN-β/ISG56/CXCL10 expression in BEAS-2B bronchial epithelial cells.

Kobori Y, Tachizaki M, Imaizumi T, Tanaka Y, Seya K, Miki Y, Kawaguchi S, Matsumiya T, Tobisawa Y, Ohyama C, Tasaka S

Molecular biology reports   51 ( 1 )   417   2024.3

TMEM2 suppresses TLR3-mediated IFN-β/ISG56/CXCL10 expression in BEAS-2B bronchial epithelial cells.

Kobori Y, Tachizaki M, Imaizumi T, Tanaka T, Seya K, Miki Y, Kawaguchi S, Matsumiya T, Tobisawa Y, Ohyama C, Tasaka S.

Mol Biol Rep.   2024.3

Distinction of ALK fusion gene- and EGFR mutation-positive lung cancer with tumor markers.

Akita T, Ariyasu R, Kakuto S, Miyadera K, Kiritani A, Tsugitomi R, Amino Y, Uchibori K, Kitazono S, Yanagitani N, Tasaka S, Nishio M.

Thorac Cancer   2024.2

Distinction of ALK fusion gene- and EGFR mutation-positive lung cancer with tumor markers.

Akita T, Ariyasu R, Kakuto S, Miyadera K, Kiritani A, Tsugitomi R, Amino Y, Uchibori K, Kitazono S, Yanagitani N, Tasaka S, Nishio M

Thoracic cancer   15 ( 10 )   788 - 796   2024.2

Role of G-protein-coupled estrogen receptor in the pathogenesis of chronic asthma.

Itoga M, Ishioka Y, Makiguchi T, Tanaka H, Taima K, Saito N, Tomita H, Tasaka S.

Immunol Lett   2024.2

Role of G-protein-coupled estrogen receptor in the pathogenesis of chronic asthma.

Itoga M, Ishioka Y, Makiguchi T, Tanaka H, Taima K, Saito N, Tomita H, Tasaka S

Immunology letters   265   16 - 22   2024.2

Predictors of efficacy of anamorelin in patients with non‑small cell lung cancer and cachexia: A retrospective study.

Ishioka Y, Tanaka H, Makiguchi T, Fujishima S, Nunomura Y, Sakamoto H, Shiratori T, Taima K, Tasaka S

Oncology letters   27 ( 1 )   22   2024.1

急性呼吸窮迫症候群（ARDS）．

田坂定智

門脇 孝，小室一成，宮地良樹 監修．日常診療に活かす診療ガイドラインUP-TO-DATE 2024-2025   2024

A Case of Disseminated Non-tuberculous Mycobacteriosis with a Skull Lesion Controlled by Resection after Exacerbation during Antimicrobial Chemotherapy in a Patient Positive for Anti-IFN-γ-neutralizing Autoantibodies

Chubachi Kei, Taima Kageaki, ishidoya Mina, Tanaka Yusuke, Kurose Akira, Tasaka Sadatomo

Internal Medicine   advpub ( 0 )   2024

Clinical efficacy and safety of multipotent adult progenitor cells (invimestrocel) for acute respiratory distress syndrome (ARDS) caused by pneumonia: a randomized, open-label, standard therapy-controlled, phase 2 multicenter study (ONE-BRIDGE).

Ichikado K, Kotani T, Kondoh Y, Imanaka H, Johkoh T, Fujimoto K, Nunomiya S, Kawayama T, Sawada M, Jenkins E, Tasaka S, Hashimoto S.

Stem Cell Res Ther.   2023.8

Clinical efficacy and safety of multipotent adult progenitor cells (invimestrocel) for acute respiratory distress syndrome (ARDS) caused by pneumonia: a randomized, open-label, standard therapy-controlled, phase 2 multicenter study (ONE-BRIDGE).

Ichikado K, Kotani T, Kondoh Y, Imanaka H, Johkoh T, Fujimoto K, Nunomiya S, Kawayama T, Sawada M, Jenkins E, Tasaka S, Hashimoto S

Stem cell research & therapy   14 ( 1 )   217   2023.8

第1土曜特集 ARDSの治療戦略--個別化診療への道筋 その他の治療 ARDSに対する間葉系幹細胞治療

田坂 定智

医学のあゆみ   286 ( 1 )   98 - 102   2023.7

Safety and effectiveness of sarilumab in Japanese patients with rheumatoid arthritis refractory to previous treatments: An interim analysis of a post-marketing surveillance.

Kameda H, Tasaka S, Takahashi T, Suzuki K, Soeda N, Tanaka Y.

Modern Rheumatol   2023.6

Safety and effectiveness of sarilumab in Japanese patients with rheumatoid arthritis refractory to previous treatments: An interim analysis of a post-marketing surveillance.

Kameda H, Tasaka S, Takahashi T, Suzuki K, Soeda N, Tanaka Y

Modern rheumatology   34 ( 3 )   444 - 452   2023.6

Differential proteomic analysis and pathogenic effects of outer membrane vesicles derived from Acinetobacter baumannii under normoxia and hypoxia.

Suzuki S, Subsomwong P, Narita K, Kawai N, Ishiai T, Teng W, Sukchawalit R, Nakane A, Tasaka S, Asano K.

PLoS One   2023.5

特集 喘嗚がある患者に出会ったら-病態をカテゴライズして診断する [Chapter 2]　喘鳴をカテゴライズする 呼吸器疾患を疑う喘鳴

糸賀 正道, 田坂 定智

内科   131 ( 5 )   1075 - 1079   2023.5

特集 COPD-実地診療にガイドラインをどう活かすか Ⅲ.トピックス 加熱式タバコによる呼吸機能障害とCOPD

田坂 定智

呼吸器ジャーナル   71 ( 2 )   286 - 291   2023.5

Safety and feasibility of carboplatin and paclitaxel in combination with nintedanib for non-small cell lung cancer patients with idiopathic pulmonary fibrosis: A prospective pilot study.

Makiguchi T, Tanaka H, Okudera K, Taima K, Tasaka S.

Transl Lung Cancer Res.   2023.4

Safety and feasibility of carboplatin and paclitaxel in combination with nintedanib for non-small cell lung cancer patients with idiopathic pulmonary fibrosis: a prospective pilot study.

Makiguchi T, Tanaka H, Okudera K, Taima K, Tasaka S

Translational lung cancer research   12 ( 4 )   719 - 726   2023.4

Granulomatosis with Polyangiitis following COVID-19 in an Adolescent.

Nakamura Y, Okumura F, Nihei M, Chubachi K, Sakamoto H, Ishioka Y, Makiguchi T, Tanaka H, Taima K, Yajima N, Kurose A, Tasaka S.

Intern Med.   62 ( 4 )   589 - 593   2023.2

Granulomatosis with Polyangiitis following COVID-19 in an Adolescent

Nakamura Yume, Okumura Fumihiko, Nihei Mayumi, Chubachi Kei, Sakamoto Hiroaki, Ishioka Yoshiko, Makiguchi Tomonori, Tanaka Hisashi, Taima Kageaki, Yajima Nobuhisa, Kurose Akira, Tasaka Sadatomo

Internal Medicine   62 ( 4 )   589 - 593   2023.2

Differential proteomic analysis and pathogenic effects of outer membrane vesicles derived from Acinetobacter baumannii under normoxia and hypoxia.

Suzuki S, Phawinee S, Narita K, Kawai N, Ishiai T, Teng W, Sukchawalit R, Nakane A, Tasaka S, Asano K.

PLoS One.   18 ( 3 )   2023.2

Differential proteomic analysis and pathogenic effects of outer membrane vesicles derived from Acinetobacter baumannii under normoxia and hypoxia.

Suzuki S, Subsomwong P, Narita K, Kawai N, Ishiai T, Teng W, Sukchawalit R, Nakane A, Tasaka S, Asano K

PloS one   18 ( 3 )   e0283109   2023

呼吸器疾患を疑う喘鳴

糸賀正道，田坂定智．

内科   2023

加熱式タバコによる呼吸機能障害とCOPD

田坂定智

呼吸器ジャーナル   2023

ARDSの病態と疾患フェノタイプ．

田坂定智

呼吸器内科   43(5)   2023

ARDSに対する間葉系幹細胞治療

田坂定智

医学のあゆみ   2023

Acute Exacerbation of Interstitial Lung Disease After SARS-CoV-2 Vaccination: A Case Series.

Ishioka Y, Makiguchi T, Itoga M, Tanaka H, Taima K, Goto S, Tasaka S

162 ( 6 )   e311 - e316   2022.12

Long-term safety of Prolastin®-C, an alpha1-proteinase inhibitor, in Japanese patients with alpha1-antitrypsin deficiency.

Seyama K, Suzuki M, Tasaka S, Nukiwa T, Sato T, Konno S, Sorrells S, Chen J, Aragonés ME, Minamino H

Respiratory investigation   60 ( 6 )   831 - 839   2022.11

Toll-like receptor 3 signaling induces interferon-induced transmembrane protein 1 in BEAS-2B cells.

Dobashi M, Shiratori T, Imaizumi T, Hashimoto S, Kawaguchi S, Seya K, Tasaka S

Experimental biology and medicine (Maywood, N.J.)   247 ( 21 )   1917 - 1922   2022.11

Feasibility and safety of platinum-doublet therapy in patients with small-cell lung cancer in the third-line setting: A multi-institutional retrospective study.

Fukushima T, Makiguchi T, Tanaka Y, Chubachi K, Ishidoya M, Suzuki S, Tanaka H, Taima K, Hasegawa Y, Okudera K, Tasaka S

Oncology letters   24 ( 4 )   368   2022.10

クライオバイオプシーで診断した肺クリプトコックス症の1例．

小田切 遥, 牧口 友紀, 福島 高志, 石岡 佳子, 糸賀 正道, 田中 寿志, 當麻 景章, 田坂 定智．

気管支学（日本呼吸器内視鏡学会雑誌)   44 ( 5 )   325 - 330   2022.9

A Case of Pulmonary Cryptococcosis Diagnosed with a Cryobiopsy

Odagiri Haruka, Makiguchi Tomonori, Fukushima Takashi, Ishioka Yoshiko, Itoga Masamichi, Tanaka Hisashi, Taima Kageaki, Tasaka Sadatomo

The Journal of the Japan Society for Respiratory Endoscopy   44 ( 5 )   325 - 330   2022.9

Toll-like receptor 3 signaling induces interferon-induced transmembrane protein 1 in BEAS-2B cells.

Dobashi M, Shiratori T, Imaizumi T, Hashimoto S, Kawaguchi S, Seya K, Tasaka S.

Exp Biol Med   247   1917 - 1922   2022.9

Feasibility and safety of platinum-doublet therapy in patients with small-cell lung cancer in the third-line setting: A multi-institutional retrospective study.

Fukushima T, Makiguchi T, Tanaka Y, Chubachi K, Ishidoya M, Suzuki S, Tanaka H, Taima K, Hasegawa Y, Okudera K, Tasaka S.

Oncol Lett.   24 ( 4 )   368   2022.9

特集 エキスパートがお答えします! 日常臨床のあるあるの疑問 第2章:呼吸器 健診異常で肺野に単発の結節影を指摘された患者が受診されました.どうすればよいでしょうか?

牧口 友紀, 田坂 定智

内科   130 ( 3 )   370 - 372   2022.9

HER2遺伝子変異陽性肺癌に対して化学放射線療法後にデュルバルマブを投与した1例．

佐々木悠子，田中寿志，牧口友紀，小堀由璃，小田切遥，田坂定智．

日本呼吸器学会誌   11(5)   310 - 314   2022.9

Long-term safety of Prolastin®-C, an alpha1-proteinase inhibitor, in Japanese patients with alpha1-antitrypsin deficiency.

Seyama K, Suzuki M, Tasaka S, Nukiwa T, Sato T, Konno S, Sorrells S, Chen J, Aragonés ME, Minamino H.

Respir Investig   60   831 - 839   2022.8

Prospective analysis of factors precluding the initiation of durvalumab from an interim analysis of a phase II trial of S-1 and cisplatin with concurrent thoracic radiotherapy followed by durvalumab for unresectable, locally advanced non-small-cell lung cancer in Japan (SAMURAI study).

Tanzawa S, Makiguchi T, Tasaka S, Inaba M, Ochiai R, Nakamura J, Inoue K, Kishikawa T, Nakashima M, Fujiwara K, Kohyama T, Ishida H, Kuyama S, Miyazawa N, Nakamura T, Miyawaki H, Oda N, Ishikawa N, Morinaga R, Kusaka K, Miyamoto Y, Yokoyama T, Matsumoto C, Tsuda T, Ushijima S, Shibata K, Shibayama T, Bessho A, Kaira K, Misumi T, Shiraishi K, Matsutani N, Seki N.

Ther Adv Med Oncol   14   2022.7

Morphological features of bronchiectasis in patients with non-tuberculous mycobacteriosis and interstitial pneumonia.

Tabe C, Dobashi M, Ishioka Y, Itoga M, Tanaka H, Taima K, Tasaka S.

BMC Res Notes   15   263   2022.7

Morphological features of bronchiectasis in patients with non-tuberculous mycobacteriosis and interstitial pneumonia.

Tabe C, Dobashi M, Ishioka Y, Itoga M, Tanaka H, Taima K, Tasaka S

BMC research notes   15 ( 1 )   263   2022.7

ARDS Clinical Practice Guideline Committee 2021 from the Japanese Respiratory Society, the Japanese Society of Intensive Care Medicine, and the Japanese Society of Respiratory Care Medicine. ARDS clinical practice guideline 2021.

Tasaka S, Ohshimo S, Takeuchi M, Yasuda H, Ichikado K, Tsushima K, Egi M, Hashimoto S, Shime N, Saito O, Matsumoto S, Nango E, Okada Y, Hayashi K, Sakuraya M, Nakajima M, Okamori S, Miura S, Fukuda T, Ishihara T, Kamo T, Yatabe T, Norisue Y, Aoki Y, Iizuka Y, Kondo Y, Narita C, Kawakami D, Okano H, Takeshita J, Anan K, Okazaki SR, Taito S, Hayashi T, Mayumi T, Terayama T, Kubota Y, Abe Y, Iwasaki Y, Kishihara Y, Kataoka J, Nishimura T, Yonekura H, Ando K, Yoshida T, Masuyama T, Sanui M

Respir Investig   60   446 - 495   2022.7

ARDS Clinical Practice Guideline Committee 2021 from the Japanese Respiratory Society, the Japanese Society of Intensive Care Medicine, and the Japanese Society of Respiratory Care Medicine. ARDS clinical practice guideline 2021.

Tasaka S, Ohshimo S, Takeuchi M, Yasuda H, Ichikado K, Tsushima K, Egi M, Hashimoto S, Shime N, Saito O, Matsumoto S, Nango E, Okada Y, Hayashi K, Sakuraya M, Nakajima M, Okamori S, Miura S, Fukuda T, Ishihara T, Kamo T, Yatabe T, Norisue Y, Aoki Y, Iizuka Y, Kondo Y, Narita C, Kawakami D, Okano H, Takeshita J, Anan K, Okazaki SR, Taito S, Hayashi T, Mayumi T, Terayama T, Kubota Y, Abe Y, Iwasaki Y, Kishihara Y, Kataoka J, Nishimura T, Yonekura H, Ando K, Yoshida T, Masuyama T, Sanui M

J Intensive Care.   10 ( 32 )   2022.7

ARDS Clinical Practice Guideline 2021.

Tasaka S, Ohshimo S, Takeuchi M, Yasuda H, Ichikado K, Tsushima K, Egi M, Hashimoto S, Shime N, Saito O, Matsumoto S, Nango E, Okada Y, Hayashi K, Sakuraya M, Nakajima M, Okamori S, Miura S, Fukuda T, Ishihara T, Kamo T, Yatabe T, Norisue Y, Aoki Y, Iizuka Y, Kondo Y, Narita C, Kawakami D, Okano H, Takeshita J, Anan K, Okazaki SR, Taito S, Hayashi T, Mayumi T, Terayama T, Kubota Y, Abe Y, Iwasaki Y, Kishihara Y, Kataoka J, Nishimura T, Yonekura H, Ando K, Yoshida T, Masuyama T, Sanui M, ARDS Clinical Practice Guideline 2021 committee from the Japanese Society of Intensive Care Medicine, the Japanese Respiratory Society, and the Japanese Society of Respiratory Care Medicine

Journal of intensive care   10 ( 1 )   32   2022.7

特集 1ページでわかる内科疾患の診療ノート-"あたりまえ" のなかにある大事な視点 第1章:呼吸器 気管支喘息

糸賀 正道, 田坂 定智

内科   129 ( 4 )   539 - 542   2022.4

Diabetic ketoacidosis shortly after COVID-19 vaccination in a non–small-cell lung cancer patient receiving combination of PD-1 and CTLA-4 inhibitors: A case report.

Makiguchi T, Tanaka H, Taima K, Takayasu S, Tasaka S

Thorac Cancer   13 ( 8 )   1220 - 1223   2022.4

Diabetic ketoacidosis shortly after COVID-19 vaccination in a non-small-cell lung cancer patient receiving combination of PD-1 and CTLA-4 inhibitors: A case report.

Makiguchi T, Fukushima T, Tanaka H, Taima K, Takayasu S, Tasaka S

Thoracic cancer   13 ( 8 )   1220 - 1223   2022.4

Epidemiological investigation of the factors affecting the COVID-19 case fatality rate.

Tsuchiya J, Saito N, Itoga M, Tasaka S, Kayaba H.

Hirosaki Med J   2022.3

Granulomatosis with polyangiitis following COVID-19 in an adolescent.

Nakamura Y, Okumura F, Nihei M, Chubachi K, Sakamoto H, Ishioka Y, Makiguchi T, Tanaka H, Taima K, Yajima N, Kurose A, Tasaka S.

Intern Med   2022.2

Diabetic ketoacidosis shortly after COVID-19 vaccination in a non–small-cell lung cancer patient receiving combination of PD-1 and CTLA-4 inhibitors: A case report

2022.2

クライオバイオプシーで診断した肺クリプトコッカス症の一例．

小田切 遥，牧口友紀，福島高志，石岡佳子，糸賀正道，田中寿志，當麻景章，黒瀬 顕，田坂定智．

気管支学   44 ( 5 )   325 - 350   2022

急性呼吸促迫症候群（ARDS）．

田坂定智

門脇 孝，小室一成，宮地良樹 監修．日常診療に活かす診療ガイドラインUP-TO-DATE 2022-2023メディカルレビュー社   143 - 145   2022

生物学的製剤使用時に注意すべき肺真菌症

田坂定智

呼吸器内科   41   288 - 294   2022

１ページでわかる内科疾患の診療ノート：気管支喘息．

糸賀正道，田坂定智．

内科   129   539 - 542   2022

健診異常で肺野に単発の結節影を指摘された患者が受診されました．どうすればよいでしょうか？

牧口友紀，田坂定智

内科   130   370 - 371   2022

細菌性肺炎

當麻景章，田坂定智

カレントテラピー   40   1048 - 1053   2022

急性呼吸窮迫症候群（ARDS）

田坂定智

日本医事新報   5141   38 - 38   2022

呼吸数，測ってますか？

田坂定智

Medical Practice   39 ( 12 )   1903 - 1903   2022

急性間質性肺炎．

田坂定智

弦間昭彦 編．最新ガイドラインに基づく呼吸器疾患診療指針2023-2024   149 - 154   2022

多様化するタバコ問題の現状

田坂定智

モダンメディア   68 ( 12 )   509 - 514   2022

Pathophysiology of ARDS: What is the current understanding of pathophysiology of ARDS? ed., Tasaka S. Acute Respiratory Distress Syndrome. Advances in Diagnostic Tools and Disease Management.

Tasaka S.

Springer Nature   33 - 52   2022

Prospective analysis of factors precluding the initiation of durvalumab from an interim analysis of a phase II trial of S-1 and cisplatin with concurrent thoracic radiotherapy followed by durvalumab for unresectable, locally advanced non-small cell lung cancer in Japan (SAMURAI study).

Tanzawa S, Makiguchi T, Tasaka S, Inaba M, Ochiai R, Nakamura J, Inoue K, Kishikawa T, Nakashima M, Fujiwara K, Kohyama T, Ishida H, Kuyama S, Miyazawa N, Nakamura T, Miyawaki H, Oda N, Ishikawa N, Morinaga R, Kusaka K, Miyamoto Y, Yokoyama T, Matsumoto C, Tsuda T, Ushijima S, Shibata K, Shibayama T, Bessho A, Kaira K, Misumi T, Shiraishi K, Matsutani N, Seki N

Therapeutic advances in medical oncology   14   17588359221116603   2022

Epidemiological investigation of the factors affecting the COVID-19 case fatality rate

Tsuchiya Junichiro, Saito Norihiro, Itoga Masamichi, Tasaka Sadatomo, Kayaba Hiroyuki

Hirosaki Medical Journal   72 ( 1-4 )   34 - 42   2022

How to improve lung auscultation in daily practice

Cho Sumito, Tasaka Sadatomo

The Journal of the Japan Society for Respiratory Care and Rehabilitation   30 ( 1 )   23 - 23   2021.12

Characteristics of central nervous system progression in non-small cell lung cancer treated with crizotinib or alectinib.

Sakamoto H, Yanagitani N, Manabe R, Tsugitomi R, Ogusu S, Tozuka T, Yoshida H, Amino Y, Ariyasu R, Uchibori K, Kitazono S, Tasaka S, Nishio M

Cancer reports (Hoboken, N.J.)   4 ( 6 )   e1414   2021.12

Immune-mediated thrombocytopenia induced with durvalumab after chemoradiotherapy in a non-small cell lung cancer patient: A case report.

Makiguchi T, Tanaka H, Kamata K, Taima K, Kurose A, Tasaka S

Thoracic cancer   12 ( 20 )   2811 - 2814   2021.10

Immune-mediated thrombocytopenia induced with durvalumab after chemoradiotherapy in a non-small cell lung cancer patient: A case report.

Tomonori Makiguchi, Hisashi Tanaka, Kosuke Kamata, Kageaki Taima, Akira Kurose, Sadatomo Tasaka

Thoracic cancer   12 ( 20 )   2811 - 2814   2021.8

本邦で検証が進む新型たばこ関連肺障害

田坂　定智

週刊医学界新聞   ( 第3429号 )   2021.7

The relationship between evolving sarcopenia and efficacy of immune checkpoint inhibitor in non-small cell lung cancer patients.

Makiguchi T, Tanaka H, Taima K, Tatsuo S, Iida S, Kakeda S, Tasaka S.

JCSM Clin Rep   2021.7

The relationship between evolving sarcopenia and efficacy of immune checkpoint inhibitor in non-small cell lung cancer patients

2021.7

特集 内科疾患の診断基準・病型分類・重症度 第1章　呼吸器 急性呼吸窮迫症候群(ARDS)

田坂 定智

内科   127 ( 4 )   524 - 526   2021.4

疾患と検査値の推移 急性呼吸窮迫症候群(ARDS)

田坂 定智

検査と技術   49 ( 4 )   508 - 514   2021.4

6. Diagnosis and Treatment of ARDS

Tasaka Sadatomo

Nihon Naika Gakkai Zasshi   110 ( Suppl )   107b - 108a   2021.2

Procalcitonin expression in patients with large cell neuroendocrine carcinoma of the lung.

Masamichi Itoga, Hisashi Tanaka, Kageaki Taima, Yoshiko Ishioka, Hiroaki Sakamoto, Shingo Takanashi, Akira Kurose, Sadatomo Tasaka

BMC research notes   14 ( 1 )   25 - 25   2021.1

Activity and bioavailability of tepotinib for leptomeningeal metastasis of NSCLC with MET exon 14 skipping mutation.

Hisashi Tanaka, Kageaki Taima, Tomonori Makiguchi, Junichi Nakagawa, Takenori Niioka, Sadatomo Tasaka

Cancer communications (London, England)   41 ( 1 )   83 - 87   2021.1

Activity and bioavailability of tepotinib for leptomeningeal metastasis of NSCLC with MET exon 14 skipping mutation

6. Tanaka H, Taima K, Makiguchi T, Nakagawa J, Niioka T, Tasaka S.

Cancer Commun (Lond)   2021.1

Procalcitonin expression in patients with large cell neuroendocrine carcinoma of the lung.

5. Itoga M, Tanaka H, Taima K, Ishioka Y, Sakamoto H, Takanashi S, Kurose A, Tasaka S.

BMC Res Notes   14 ( 25 )   2021

A Phase I/II study of biweekly carboplatin and nab-paclitaxel with concurrent radiotherapy for patients with locally advanced unresectable stage III non-small cell lung cancer.

Tanaka H, Hasegawa Y, Makiguchi T, Okumura F, Tabe C, Shiratori T, Ishioka Y, Itoga M, Taima K, Yokouchi J, Hatayama Y, Aoki M, Tasaka S.

Clin Lung Cancer   22(1)   42 - 48   2021

易感染宿主の肺炎

田坂　定智

臨牀と研究   98   1363 - 1367   2021

リウマチ性疾患患者における間質性肺疾患の診断

田坂　定智

リウマチ科   65(1)   20 - 27   2021

ARDSの疾患フェノタイプと治療

田坂　定智

ICUとCCU   45(3)   149 - 153   2021

加熱式たばこ・電子たばこの肺障害

田坂　定智

臨床リハ   30(10)   1051 - 1055   2021

The efficacy of nintedanib in 158 patients with idiopathic pulmonary fibrosis in real-world settings: A multicenter retrospective study.

Dobashi M, Tanaka H, Taima K, Itoga M, Ishioka Y, Shiratori T, Okumura F, Tabe C, Tanaka Y, Morimoto T, Hasegawa Y, Yasugahira H, Okudera K, Takanashi S, Tasaka S

SAGE open medicine   9   20503121211023357   2021

日本臨床　領域別症候群シリーズ　腫瘍性疾患　「Pancoast症候群」

田中　寿志、田坂　定智

肺癌診療ガイドライン　2021年度版   2021

The efficacy of nintedanib in 158 patients with idiopathic pulmonary fibrosis in real-world settings: A multicenter retrospective study.

Masaki Dobashi, Hisashi Tanaka, Kageaki Taima, Masamichi Itoga, Yoshiko Ishioka, Toshihiro Shiratori, Fumihiko Okumura, Chiori Tabe, Yoshihito Tanaka, Takeshi Morimoto, Yukihiro Hasegawa, Hideo Yasugahira, Koichi Okudera, Shingo Takanashi, Sadatomo Tasaka

SAGE open medicine   9   20503121211023357 - 20503121211023357   2021

Hypothesis generative head-to-head study comparing efficacy of afatinib and osimertinib based on immunological biomarkers in Japanese NSCLC patients with EGFR mutations (Heat on Beat study).

Kei Morikawa, Hisashi Tanaka, Hidetoshi Itani, Saori Takata, Satoshi Watanabe, Kazuma Kishi, Kenzo Soejima, Kyoichi Kaira, Hiroshi Kagamu, Kenichi Yoshimura, Noriyuki Matsutani, Nobuhiko Seki

Therapeutic advances in medical oncology   12   1758835920967254 - 1758835920967254   2020.10

A Phase I/II Study of Biweekly Carboplatin and Nab-paclitaxel With Concurrent Radiotherapy for Patients With Locally Advanced Unresectable Stage III Non-small-cell Lung Cancer.

Hisashi Tanaka, Yukihiro Hasegawa, Tomonori Makiguchi, Fumihiko Okumura, Chiori Tabe, Toshihiro Shiratori, Yoshiko Ishioka, Masamichi Itoga, Kageaki Taima, Junichi Yokouchi, Yoshiomi Hatayama, Masahiko Aoki, Sadatomo Tasaka

Clinical lung cancer   22 ( 1 )   42 - 48   2020.10

Effect of nintedanib on non-small cell lung cancer in a patient with idiopathic pulmonary fibrosis: A case report and literature review.

Toshihiro Shiratori, Hisashi Tanaka, Chiori Tabe, Junichiro Tsuchiya, Yoshiko Ishioka, Masamichi Itoga, Kageaki Taima, Shingo Takanashi, Sadatomo Tasaka

Thoracic cancer   11 ( 6 )   1720 - 1723   2020.6

Destroyed lung due to sustained inflammation after chemoradiotherapy followed by durvalumab.

Kageaki Taima, Hisashi Tanaka, Masamichi Itoga, Yoshiko Ishioka, Akira Kurose, Sadatomo Tasaka

Respirology case reports   8 ( 5 )   e00580 - e00580   2020.5

ISG56 is involved in CXCL10 expression induced by TLR3 signaling in BEAS-2B bronchial epithelial cells.

Toshihiro Shiratori, Tadaatsu Imaizumi, Koji Hirono, Shogo Kawaguchi, Tomoh Matsumiya, Kazuhiko Seya, Sadatomo Tasaka

Experimental lung research   46 ( 6 )   195 - 202   2020.5

A pilot study of adjuvant chemotherapy with carboplatin and oral S-1 for patients with completely resected stage II to IIIA non-small cell lung cancer

Tanaka H, Tabe C, Okumura F, Shiratori T, Ishioka Y, Itoga M, Taima K, Morimoto T, Kimura D, Tsushima T, Tasaka S.

Thorac Cancer   11   1633 - 1638   2020.4

Recent Advances in the Diagnosis and Management of Pneumocystis Pneumonia.

Tasaka S

Tuberculosis and respiratory diseases   83 ( 2 )   132 - 140   2020.4

繰り返す血胸・気胸を契機に診断された血管型Ehlers-Danlos症候群

石岡佳子，白鳥俊博，當麻景章，糸賀正道，林 周次郎，田坂定智

日呼吸誌   9 ( 6 )   473 - 476   2020

A Case of Large Cell Neuroendocrine Carcinoma Successfully Treated with Nivolumab

Tabe Chiori, Tanaka Hisashi, Taima Kageaki, Itoga Masamichi, Shiratori Toshihiro, Tasaka Sadatomo

Haigan   59 ( 7 )   1156 - 1161   2019.12

特集 高齢者の呼吸器感染症治療-症例が示すマネジメントの最前線 ◉肺真菌症 ③ニューモシスチス

田坂 定智

感染と抗菌薬   22 ( 4 )   280 - 284   2019.12

Simultaneous Detection of the T790M and L858R Mutations in the EGFR Gene by Oligoribonucleotide Interference-PCR

Keisuke Baba, Toshitsugu Fujita, Sadatomo Tasaka, Hodaka Fujii

International Journal of Molecular Sciences   20 ( 16 )   2019.8

特集 今日の呼吸器診療と今後の展望 知っておきたい呼吸器疾患 急性呼吸窮迫症候群(ARDS)

田坂 定智

内科   124 ( 1 )   1459 - 1461   2019.7

Obesity worsens the outcome of influenza virus infection associated with impaired type I interferon induction in mice.

Ho Namkoong, Makoto Ishii, Hideki Fujii, Takahiro Asami, Kazuma Yagi, Shoji Suzuki, Shuhei Azekawa, Sadatomo Tasaka, Naoki Hasegawa, Tomoko Betsuyaku

Biochemical and Biophysical Research Communications   513 ( 2 )   405 - 411   2019.5

Real-world study of afatinib in first-line or re-challenge settings for patients with EGFR mutant non-small cell lung cancer.

Hisashi Tanaka, Kageaki Taima, Masamichi Itoga, Yoshiko Ishioka, Keisuke Baba, Toshihiro Shiratori, Hiroaki Sakamoto, Junichiro Tsuchiya, Hideyuki Nakagawa, Yukihiro Hasegawa, Hideo Yasugahira, Koichi Okudera, Shingo Takanashi, Sadatomo Tasaka

Medical oncology   36 ( 6 )   57 - 57   2019.5

The efficacy of immune checkpoint inhibitors in advanced non-small cell lung cancer harboring driver mutations.

Sakamoto H, Tanaka H, Shiratori T, Baba K, Ishioka Y, Itoga M, Taima K, Hasegawa Y, Takanashi S, Tasaka S.

Molecular and Clinical Oncology   10 ( 6 )   610 - 614   2019.4

Prognostic values of the Berlin definition criteria, blood lactate level, and fibroproliferative changes on high-resolution computed tomography in ARDS patients.

Tetsuro Kamo, Sadatomo Tasaka, Takeshi Suzuki, Takanori Asakura, Shoji Suzuki, Kazuma Yagi, Ho Namkoong, Makoto Ishii, Hiroshi Morisaki, Tomoko Betsuyaku

BMC Pulmonary Medicine   19 ( 1 )   37 - 37   2019.2

Efficacy of pembrolizumab for patients with both high PD-L1 expression and an MET exon 14 skipping mutation: A case report.

Keisuke Baba, Hisashi Tanaka, Hiroaki Sakamoto, Toshihiro Shiratori, Junichiro Tsuchiya, Yoshiko Ishioka, Masamichi Itoga, Kageaki Taima, Sadatomo Tasaka

Thoracic Cancer   10 ( 2 )   369 - 372   2019.2

肺動脈と交通しmosaic attenuationを呈した縦隔型気管支動脈瘤

石岡佳子，當麻景章，糸賀正道，坂本博昭，掛端伸也，田坂定智

日本呼吸器学会誌   8 ( 1 )   72 - 75   2019.1

cell expansion and inhibits lymphocyte infiltration in the lungs to ameliorate murine pulmonary emphysema.

Takanori Asakura, Makoto Ishii, Ho Namkoong, Shoji Suzuki, Shizuko Kagawa, Kazuma Yagi, Takaki Komiya, Takafumi Hashimoto, Satoshi Okamori, Hirofumi Kamata, Sadatomo Tasaka, Akio Kihara, Ahmed E Hegab, Naoki Hasegawa, Tomoko Betsuyaku

Mucosal immunology   11 ( 6 )   1606 - 1620   2018.11

脊髄炎，感覚性軸索型ニューロパチーを呈した傍腫瘍性神経症候群の1例

土屋純一郎，田中寿志，當麻景章，中村琢洋，髙梨信吾，田坂定智．

日本呼吸器学会誌   7 ( 4 )   212 - 215   2018.7

Emergency Radiotherapy for Spinal Cord Compression due to Bone Sarcoidosis.

Tanaka Y, Taima K, Tanaka H, Itoga M, Ishioka Y, Shiratori T, Tsuchiya J, Sakamoto H, Takanashi S, Tasaka S.

Internal Medicine   2018.3

Anti-inflammatory roles of mesenchymal stromal cells during acute Streptococcus pneumoniae pulmonary infection in mice.

Asami T, Ishii M, Namkoong H, Yagi K, Tasaka S, Asakura T, Suzuki S, Kamo T, Okamori S, Kamata H, Zhang H, Hegab AE, Hasegawa N, Betsuyaku T.

Cytotherapy   2018.3

Clarithromycin expands CD11b+Gr-1+ cells via the STAT3/Bv8 axis to ameliorate lethal endotoxic shock and post-influenza bacterial pneumonia.

Namkoong H, Ishii M, Fujii H, Yagi K, Asami T, Asakura T, Suzuki S, Kamata H, Tasaka S, Hasegawa N, Koyasu S, Betsuyaku T.

PLoS Pathogens   2018.3

A phase I study of afatinib for patients aged 75 or older with advanced non-small cell lung cancer harboring EGFR mutations.

Tanaka H, Taima K, Tanaka Y, Itoga M, Ishioka Y, Nakagawa H, Baba K, Hasegawa Y, Takanashi S, Tasaka S.

Medical Oncology   2018.2

Clarithromycin expands CD11b+Gr-1+ cells via the STAT3/Bv8 axis to ameliorate lethal endotoxic shock and post-influenza bacterial pneumonia.

Ho Namkoong, Makoto Ishii, Hideki Fujii, Kazuma Yagi, Takahiro Asami, Takanori Asakura, Shoji Suzuki, Ahmed E Hegab, Hirofumi Kamata, Sadatomo Tasaka, Koji Atarashi, Nobuhiro Nakamoto, Satoshi Iwata, Kenya Honda, Takanori Kanai, Naoki Hasegawa, Shigeo Koyasu, Tomoko Betsuyaku

PLoS pathogens   14 ( 4 )   e1006955 - e1006955   2018

上気道における粒子付着の数値シュミレーション

藤井 沙弥佳、城田 農、笠松 裕貴、田辺 つばさ、稲村 隆夫、岡部 孝裕、田坂 定智

混相流   32 ( 1 )   132 - 139   2018

A single-arm phase II study of nab-paclitaxel for patients with chemorefractory non-small cell lung cancer.

Tanaka H, Taima K, Morimoto T, Tanaka Y, Itoga M, Nakamura K, Hayashi A, Kumagai M, Yasugahira H, Mikuniya M, Okudera K, Takanashi S, Tasaka S

BMC Cancer   2017.10

Clinical and radiological characteristics of patients with late-onset severe restrictive lung defect after hematopoietic stem cell transplantation.

Namkoong H, Ishii M, Mori T, Sugiura H, Tasaka S, Sakurai M, Koda Y, Kato J, Hasegawa N, Okamoto S, Betsuyaku T.

BMC Pulmonary Medicine   2017.9

Regression of Crizotinib-Associated Complex Cystic Lesions after Switching to Alectinib.

Taima K, Tanaka H, Tanaka Y, Itoga M, Takanashi S, Tasaka S.

Internal Medicine   2017.9

The efficacy, safety, and feasibility of inhaled amikacin for the treatment of difficult-to-treat non-tuberculous mycobacterial lung diseases.

Yagi K, Ishii M, Namkoong H, Asami T, Iketani O, Asakura T, Suzuki S, Sugiura H, Yamada Y, Nishimura T, Fujiwara H, Funatsu Y, Uwamino Y, Kamo T, Tasaka S, Betsuyaku T, Hasegawa N.

BMC Infectious Diseases   2017.8

Clinical practice of acute respiratory distress syndrome in Japan: A nationwide survey and scientific evidences.

Tasaka S, Tatsumi K

Respiratory Investigation   2017.7

The Japanese Respiratory Society Noninvasive Positive Pressure Ventilation (NPPV) Guidelines (second revised edition).

Tsuneto Akashiba, Yuka Ishikawa, Hideki Ishihara, Hideaki Imanaka, Motoharu Ohi, Ryoichi Ochiai, Takatoshi Kasai, Kentaro Kimura, Yasuhiro Kondoh, Shigeru Sakurai, Nobuaki Shime, Masayuki Suzukawa, Misa Takegami, Shinhiro Takeda, Sadatomo Tasaka, Hiroyuki Taniguchi, Naohiko Chohnabayashi, Kazuo Chin, Tomomasa Tsuboi, Keisuke Tomii, Koji Narui, Nobuyuki Hasegawa, Ryuichi Hasegawa, Yoshihito Ujike, Keishi Kubo, Yoshinori Hasegawa, Shin-Ichi Momomura, Yoshitsugu Yamada, Masahiro Yoshida, Yukie Takekawa, Ryo Tachikawa, Satoshi Hamada, Kimihiko Murase

Respiratory investigation   55 ( 1 )   83 - 92   2017.1

市中肺炎に対するステロイド療法および非抗菌薬療法の意義

1. 糸賀正道，田坂定智

呼吸器内科   2017

急性呼吸窮迫症候群の病態・治療の最前線

田坂定智

日内会誌   2017

急性呼吸窮迫症候群（ARDS）

田坂定智

呼吸器内科   2017

Histone Deacetylase Inhibition Protects Mice Against Lethal Postinfluenza Pneumococcal Infection.

Kazuma Yagi, Makoto Ishii, Ho Namkoong, Hideki Fujii, Takahiro Asami, Shoji Suzuki, Takanori Asakura, Kosuke Mizoguchi, Tetsuro Kamo, Sadatomo Tasaka, Satoshi Iwata, Steven L Kunkel, Naoki Hasegawa, Tomoko Betsuyaku

Critical care medicine   44 ( 10 )   e980 - e987   2016.10

Clinical characteristics of pulmonary Mycobacterium scrofulaceum disease in 2001-2011: A case series and literature review.

Shoji Suzuki, Eriko Morino, Makoto Ishii, Ho Namkoong, Kazuma Yagi, Takanori Asakura, Takahiro Asami, Hiroshi Fujiwara, Yoshifumi Uwamino, Tomoyasu Nishimura, Sadatomo Tasaka, Tomoko Betsuyaku, Jin Takasaki, Satoshi Iwata, Naoki Hasegawa

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy   22 ( 9 )   611 - 616   2016.9

Clinical efficacy and safety of multidrug therapy including thrice weekly intravenous amikacin administration for Mycobacterium abscessus pulmonary disease in outpatient settings: a case series.

Ho Namkoong, Kozo Morimoto, Tomoyasu Nishimura, Hiromu Tanaka, Hiroaki Sugiura, Yoshitake Yamada, Atsuko Kurosaki, Takanori Asakura, Shoji Suzuki, Hiroshi Fujiwara, Kazuma Yagi, Makoto Ishii, Sadatomo Tasaka, Tomoko Betsuyaku, Yoshihiko Hoshino, Atsuyuki Kurashima, Naoki Hasegawa

BMC infectious diseases   16   396 - 396   2016.8

Consistency of interpretation of lung sounds between experienced physicians and automatic analysis using a newly developed algorithm based on the acoustic characteristics

Tasaka S, Saraya T, Kuraishi H, Simbara H, Oda K, Takizawa H.

Pulm Res Respir Med Open J   2016.6

Multiple nodular lesions following Pneumocystis pneumonia in a non-HIV immunocompromised patient.

Takanori Asakura, Naofumi Kameyama, Makoto Ishii, Ichiro Kawada, Sadatomo Tasaka, Kenzo Soejima, Tomoko Betsuyaku

Clinical case reports   4 ( 5 )   528 - 530   2016.5

Disseminated Mycobacterium marinum Infection With a Destructive Nasal Lesion Mimicking Extranodal NK/T Cell Lymphoma: A Case Report.

Takanori Asakura, Makoto Ishii, Taku Kikuchi, Kaori Kameyama, Ho Namkoong, Noboru Nakata, Kayoko Sugita, Sadatomo Tasaka, Takayuki Shimizu, Yoshihiko Hoshino, Shinichiro Okamoto, Tomoko Betsuyaku, Naoki Hasegawa

Medicine   95 ( 11 )   e3131 - e3131   2016.3

血液ガス分析検査でわかること

當麻景章，田坂定智

呼吸器内科   2016

ニューモシスチス肺炎の病態，診断と治療

田坂定智

呼吸器内科   2016

急性呼吸窮迫症候群の病態解明と治療の試み

田坂定智

弘前市医師会報   2016

ARDSや重症肺炎などの急性呼吸不全に対するNPPV

田坂定智

日胸   2016

Pharmacokinetics of intravenous peramivir in the airway epithelial lining fluid of healthy volunteers.

Yohei Funatsu, Sadatomo Tasaka, Takahiro Asami, Ho Namkoong, Hiroshi Fujiwara, Osamu Iketani, Kazuma Yagi, Yoshifumi Kimizuka, Makoto Ishii, Tomoyasu Nishimura, Haruhiko Ogata, Satoshi Iwata, Tomoko Betsuyaku, Naoki Hasegawa

Antiviral therapy   21 ( 7 )   621 - 625   2016

Diaphragm ultrasonography as a tool to assess paradoxical breathing in a patient with asthma attack

5. Mikura S, Saraya T, Minami T, Satoh T, Oda K, Shimbara H, Tasaka S, Kuraishi H, Takizawa H.

Pulm Res Respir Med Open J   2016

Blue-black trachea as a result of minocycline-induced hyperpigmentation

Asakura T, Nukaga S, Namkoong H, Yagi K, Suzuki S, Ishii M, Tasaka S, Betsuyaku T, Hasegawa N.

Am J Respir Crit Care Med   193   e5 - e6   2016

Multiple nodular lesions following Pneumocystis pneumonia in a non-HIV immunocompromised patient

Asakura T, Kameyama N, Ishii M, Kawada I, Tasaka S, Soejima K, Betsuyaku T.

Clin Case Rep   4   528 - 530   2016

Theory and strategy for Pneumococcal vaccines in the elderly.

Ho Namkoong, Makoto Ishii, Yohei Funatsu, Yoshifumi Kimizuka, Kazuma Yagi, Takahiro Asami, Takanori Asakura, Shoji Suzuki, Testuro Kamo, Hiroshi Fujiwara, Sadatomo Tasaka, Tomoko Betsuyaku, Naoki Hasegawa

Human vaccines & immunotherapeutics   12 ( 2 )   336 - 343   2016

Levels of Soluble Receptor for Advanced Glycation End Products in Bronchoalveolar Lavage Fluid in Patients with Various Inflammatory Lung Diseases.

Tetsuro Kamo, Sadatomo Tasaka, Yuriko Tokuda, Shoji Suzuki, Takanori Asakura, Kazuma Yagi, Ho Namkoong, Makoto Ishii, Naoki Hasegawa, Tomoko Betsuyaku

Clinical medicine insights. Circulatory, respiratory and pulmonary medicine   9 ( Suppl 1 )   147 - 154   2015

臨牀と研究

田坂定智（ Role： Joint author）

大道学館  2018.11 

THE LUNG perspectives 26

田坂定智（ Role： Joint author）

メディカルレビュー社  2018.6 

呼吸器疾患の薬物療法を極める

田坂定智（ Role： Joint author）

文光堂  2018.4 

Shock 32

田坂定智（ Role： Joint author）

日本Shock学会  2018 

呼吸器内科 34〔Suppl. 1〕呼吸器内科診療マニュアル

田坂定智（ Role： Joint author）

科学評論社  2018 

Lung disease associated with rheumatoid arthritis

Tasaka S（ Role： Joint author）

Springer Singapore  2018 

気管支肺胞洗浄（BAL）法の手引き 改訂第3版

田坂定智（ Role： Sole author ,  ニューモシスチス肺炎）

日本呼吸器学会びまん性肺疾患学術部会  2017.10 

肺水腫

田坂定智

矢崎義雄 監修．新臨床内科学 第10版   173 - 177   2020

急性呼吸促迫症候群（ARDS）

田坂定智

門脇 孝，小室一成，宮地良樹 監修．日常診療に活かす診療ガイドライン   UP-TO-DATE 2020-2021   148 - 150   2020

薬剤性間質性肺疾患 生物学的製剤

田坂定智

久保惠嗣 監修．間質性肺疾患診療マニュアル 改訂第3版   394 - 396   2020

急性間質性肺炎

田坂定智

弦間昭彦 編．最新ガイドラインに基づく呼吸器疾患診療指針   2021-2022   144 - 149   2020

重症肺炎の治療・管理（ARDSも含めて）

田坂定智

Medical Practice   37 ( 10 )   1498 - 1503   2020

急性呼吸窮迫症候群

田坂定智

日本呼吸器学会 編．新 呼吸器専門医テキスト改訂第2版   439 - 443   2020

ニューモシスチス

田坂　定智

感染と抗菌薬   22 ( 4 )   280 - 284   2019.12

知っておきたい呼吸器疾患 急性呼吸窮迫症候群（ARDS）

田坂　定智

内科   124 ( 1 )   1459 - 1461   2019.7

呼吸器疾患の遠隔診療

田坂　定智

日本小児呼吸器学会雑誌   30   67 - 70   2019

成人期間質性肺疾患－その特徴と移行期医療－

田坂　定智

日本小児呼吸器学会雑誌   30   113 - 116   2019

ARDSの病態と疾患フェノタイプ

田坂定智

呼吸器内科   33 ( 1 )   1 - 8   2018.1

重症肺炎とその治療

田坂定智

最新医学 別冊 診断と治療のABC 129 呼吸器感染症   2017.12

Consensus statements for medical practice: Biological agents and lung disease

Tokuda H, Harigai M, Kameda H, Tomono K, Takayanagi N, Watanabe A, Tasaka S, Suda T, Tateda K, Kadota J.

Respiratory Investigation   55 ( 3 )   229 - 251   2017.5