論文 - 中島 晶
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SLC10A4 is a protease-activated transporter that transports bile acids.
Abe T, Kanemitu Y, Nakasone M, Kawahata I, Yamakuni T, Nakajima A, Suzuki N, Nishikawa M, Hishinuma T, Tomioka Y
J Biochem. 154 93 - 101 2013年
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Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice.
Ibi D, Nagai T, Nakajima A, Mizoguchi H, Kawase T, Tsuboi D, Kano SI, Sato Y, Hayakawa M, Lange UC, Adams DJ, Surani MA, Satoh T, Sawa A, Kaibuchi K, Nabeshima T, Yamada K
Glia. 61 679 - 693 2013年
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Potent activity of nobiletin-rich Citrus reticulata peel extract to facilitate cAMP/PKA/ERK/CREB signaling associated with learning and memory in cultured hippocampal neurons: identification of the substances responsible for the pharmacological action.
Kawahata I, Yoshida M, Sun W, Nakajima A, Lai Y, Osaka N, Matsuzaki K, Yokosuka A, Mimaki Y, Naganuma A, Tomioka Y, Yamakuni T
J Neural Transm. 120 1397 - 1409 2013年
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Nobiletin, a citrus flavonoid, ameliorates cognitive impairment, oxidative burden, and hyperphosphorylation of tau in senescence-accelerated mouse.
Nakajima A, Aoyama Y, Nguyen TY, Shin EJ, Kim HC, Yamada S, Nakai T, Nagai T, Yokosuka A, Mimaki Y, Ohizumi Y, Yamada K
Behav Brain Res. 250 351 - 360 2013年
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Repeated treatment with nicotine induces phosphorylation of NMDA receptor NR2B subunit in the brain regions involved in behavioral sensitization.
Nakajima A, Kinugasa Y, Torii J, Hishinuma T, Tomioka Y, Yamada K, Yamakuni T
Neurosci Lett. 524 133 - 138 2012年
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Post-training dephosphorylation of eEF-2 promotes protein synthesis for memory consolidation.
Im HI, Nakajima A, Gong B, Xiong X, Mamiya T, Gershon ES, Zhuo M, Tang YP
PLoS ONE. 13 e7424 2009年
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Nobiletin improves brain ischemia-induced learning and memory deficits through stimulation of CaMKII and CREB phosphorylation.
Yamamoto Y, Shioda N, Han F, Moriguchi S, Nakajima A, Yokosuka A, Mimaki Y, Sashida Y, Yamakuni T, Ohizumi Y, Fukunaga K
Brain Res. 1295 218 - 229 2009年
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4´-Demethylnobiletin, a bioactive metabolite of nobiletin enhancing PKA/ERK/CREB signaling, rescues learning impairment associated with NMDA receptor-antagonism via stimulation of ERK cascade.
Rahim Md Al, Nakajima A, Saigusa D, Tetsu N, Maruyama Y, Shibuya M, Yamakoshi H, Tomioka Y, Iwabuchi Y, Ohizumi Y, Yamakuni T
Biochemistry. 18 7713 - 7721 2009年
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Neurobehavioral effects of tetrabromobisphenol A, a brominated flame retardant, in mice.
Nakajima A, Saigusa D, Tetsu N, Yamakuni T, Tomioka Y, Hishinuma T
Toxicol Lett. 189 78 - 83 2009年
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A novel diol-derivative of chalcone produced by bioconversion, 3-(2,3-dihydroxyphenyl)-1-phenylpropan-1-one, activates PKA/MEK/ERK signaling and antagonizes Aβ-inhibition of the cascade in cultured rat CNS neurons.
Rahim Md Al, Nakajima A, Misawa N, Shindo K, Adachi K, Shizuri Y, Ohizumi Y, Yamakuni T
Eur J Pharmacol. 600 10 - 17 2008年
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Adult neurogenesis is functionally associated with AD-like neurodegeneration.
Chen Q, Nakajima A, Choi SH, Xiong X, Sisodia SS, Tang YP
Neurobiol Dis. 29 316 - 326 2008年
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Loss of presenilin function causes Alzheimer's disease-like neurodegeneration in the mouse.
Chen Q, Nakajima A, Choi SH, Xiong X, Tang YP
J Neurosci Res. 86 1615 - 1625 2008年
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Expression of NR2B in Cerebellar Granule Cells Specifically Facilitates Effect of Motor Training on Motor Learning.
Jiao J, Nakajima A, Janssen WG, Bindokas VP, Xiong X, Morrison JH, Brorson JR, Tang YP
PLoS ONE. 3 ( e1684 ) 1 - 11 2008年
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Nobiletin, a citrus flavonoid, improves memory impairment and Aβ pathology in a transgenic mouse model of Alzheimer’s disease.
Onozuka H, Nakajima A, Matsuzaki K, Shin RW, Ogino K, Saigusa D, Tetsu N, Yokosuka A, Sashida Y, Mimaki Y, Yamakuni T, Ohizumi Y
J Pharmacol Exp Ther. 326 739 - 744 2008年
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Nobiletin, a citrus flavonoid that improves memory impairment, rescues bulbectomy-induced cholinergic neurodegeneration in mice.
Nakajima A, Yamakuni T, Haraguchi M, Omae N, Song SY, Kato C, Tadano T, Yokosuka A, Mimaki Y, Sashida Y, Ohizumi Y
J Pharmacol Sci. 105 122 - 126 2007年
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An inducer for glial cell line-derived neurotrophic factor and tumor necrosis factor-alpha protects against methamphetamine-induced rewarding effects and sensitization.
Niwa M, Nitta A, Yamada Y, Nakajima A, Saito K, Seishima M, Shen L, Noda Y, Furukawa S, Nabeshima T
Biol Psychiatry. 61 890 - 901 2007年
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TNF-alpha and its inducer inhibit morphine-induced rewarding effects and sensitization.
Niwa M, Nitta A, Yamada Y, Nakajima A, Saito K, Seishima M, Noda Y, Nabeshima T
Biol Psychiatry. 62 658 - 668 2007年
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Nobiletin, a citrus flavonoid, reverses learning impairment associated with NMDA receptor antagonism by activation of ERK signaling.
Nakajima A, Yamakuni T, Matsuzaki K, Nakata N, Onozuka H, Yokosuka A, Sashida Y, Mimaki Y, Ohizumi Y
J Pharmacol Exp Ther. 321 784 - 790 2007年
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Discriminative-stimulus effects of methamphetamine and morphine in rats are attenuated by cAMP-related compounds.
Yan Y, Nitta A, Mizuno T, Nakajima A, Yamada K, Nabeshima T
Behav Brain Res. 173 39 - 46 2006年
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Elevated cholecystokininergic tone constitutes an important molecular/neuronal mechanism for the expression of anxiety in the mouse.
Chen Q, Nakajima A, Meacham C, Tang YP
Proc Natl Acad Sci USA. 103 3881 - 3886 2006年