Updated on 2024/07/03

写真a

 
KAWAGUCHI Shogo
 
Affiliation
Graduate School of Medicine F F
External link

Degree

  • 博士(医学)

Research Interests

  • 血管内皮細胞

  • 自然免疫

  • 腸血管バリア

  • 脂肪性肝炎

  • 粘膜免疫

  • 粘膜バリア機能

  • 炎症性腸疾患

  • マクロファージ

  • RIG-I

  • MDA5

Research Areas

  • Life Science / Cell biology

  • Life Science / Gastroenterology

  • Life Science / Immunology

Professional Memberships

  • 日本消化器免疫学会

  • 日本神経消化器病学会

  • 日本肝臓学会

  • 日本消化管学会

  • 日本消化器内視鏡学会

  • 日本消化器病学会

  • 日本内科学会

  • 日本神経消化器病学会

  • 日本消化器内視鏡学会

  • 日本消化器免疫学会

  • 日本内科学会

  • 弘前医学会

  • 日本消化器がん検診学会

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Papers

  • Interferon-stimulated gene 56 positively regulates Toll-like receptor 3-mediated CXCL10 expression in human renal proximal tubular epithelial cells.

    Tachizaki M, Sakamoto S, Kobori Y, Asano Y, Kawaguchi S, Seya K, Tanaka H, Morita E, Imaizumi T

    FEBS open bio   2024.6

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  • Resiquimod Induces C-C Motif Chemokine Ligand 2 Via Nuclear Factor-Kappa B in SH-SY5Y Human Neuroblastoma Cells.

    Masatoshi Kaizuka, Shogo Kawaguchi, Tetsuya Tatsuta, Mayuki Tachizaki, Yuri Kobori, Yusuke Tanaka, Kazuhiko Seya, Tomoh Matsumiya, Tadaatsu Imaizumi, Hirotake Sakuraba

    Neuromolecular medicine   26 ( 1 )   16 - 16   2024.4

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  • TMEM2 suppresses TLR3-mediated IFN-β/ISG56/CXCL10 expression in BEAS-2B bronchial epithelial cells.

    Kobori Y, Tachizaki M, Imaizumi T, Tanaka Y, Seya K, Miki Y, Kawaguchi S, Matsumiya T, Tobisawa Y, Ohyama C, Tasaka S

    Molecular biology reports   51 ( 1 )   417   2024.3

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  • The inhibitory effect of DIF-3 on polyinosinic-polycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells.

    Araya R, Men S, Uekusa Y, Yu Z, Kikuchi H, Daitoku K, Minakawa M, Kawaguchi S, Furukawa KI, Oshima Y, Imaizumi T, Seya K

    Journal of pharmacological sciences   154 ( 3 )   157 - 165   2024.3

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  • Possible involvement of DExD/H box helicase 60 in synovial inflammation of rheumatoid arthritis: role of toll-like receptor 3 signaling.

    Nakamura Y, Ishibashi HK, Saruga T, Imaizumi T, Kurose A, Tachizaki M, Kawaguchi S, Seya K, Sasaki E, Ishibashi Y

    Molecular biology reports   51 ( 1 )   131   2024.1

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  • TLR3 signaling-induced interferon-stimulated gene 56 plays a role in the pathogenesis of rheumatoid arthritis.

    Ishibashi HK, Nakamura Y, Saruga T, Imaizumi T, Kurose A, Kawaguchi S, Seya K, Sasaki E, Ishibashi Y

    Experimental biology and medicine (Maywood, N.J.)   249   10122   2024

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  • Expression of interferon-stimulated gene 20 (ISG20), an antiviral effector protein, in glomerular endothelial cells: possible involvement of ISG20 in lupus nephritis.

    Takao Karasawa, Riko Sato, Tadaatsu Imaizumi, Masashi Fujita, Tomomi Aizawa, Koji Tsugawa, Deborah Mattinzoli, Shogo Kawaguchi, Kazuhiko Seya, Kiminori Terui, Kensuke Joh, Hiroshi Tanaka

    Renal failure   45 ( 1 )   2224890 - 2224890   2023.12

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  • Polygonum tinctorium leaf extract ameliorates high-fat diet-induced intestinal epithelial damage in mice.

    Shogo Kawaguchi, Hirotake Sakuraba, Hidezumi Kikuchi, Kota Matsuki, Yudai Hayashi, Jiangli Ding, Yusuke Tanaka, Kazuhiko Seya, Tomoh Matsumiya, Hiroto Hiraga, Shinsaku Fukuda, Kenroh Sasaki, Tadaatsu Imaizumi

    Experimental and therapeutic medicine   25 ( 3 )   112 - 112   2023.3

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  • The double-stranded RNA-dependent protein kinase PKR negatively regulates the protein expression of IFN-β induced by RIG-I signaling.

    Tomoh Matsumiya, Yuko Shiba, Jiangli Ding, Shogo Kawaguchi, Kazuhiko Seya, Tadaatsu Imaizumi

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology   37 ( 2 )   e22780   2023.2

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  • ER export signals mediate plasma membrane localization of transmembrane protein TMEM72.

    Jiangli Ding, Tomoh Matsumiya, Yasuo Miki, Ryo Hayakari, Yuko Shiba, Shogo Kawaguchi, Kazuhiko Seya, Tadaatsu Imaizumi

    The FEBS journal   290 ( 10 )   2636 - 2657   2022.12

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  • Glomerular endothelial expression of type I IFN-stimulated gene, DExD/H-Box helicase 60 via toll-like receptor 3 signaling: possible involvement in the pathogenesis of lupus nephritis.

    Takao Karasawa, Riko Sato, Tadaatsu Imaizumi, Shun Hashimoto, Masashi Fujita, Tomomi Aizawa, Koji Tsugawa, Shogo Kawaguchi, Kazuhiko Seya, Kiminori Terui, Hiroshi Tanaka

    Renal failure   44 ( 1 )   137 - 145   2022.12

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  • Toll-like receptor 3 signaling induces interferon-induced transmembrane protein 1 in BEAS-2B cells.

    Dobashi M, Shiratori T, Imaizumi T, Hashimoto S, Kawaguchi S, Seya K, Tasaka S

    Experimental biology and medicine (Maywood, N.J.)   247 ( 21 )   1917 - 1922   2022.11

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  • Polygonum tinctorium leaves suppress sodium dextran sulfate-induced colitis through interleukin-10-related pathway.

    Taka Asari, Hidezumi Kikuchi, Shogo Kawaguchi, Hirotake Sakuraba, Shukuko Yoshida, Yui Akemoto, Takato Maeda, Ota Shinji, Yasuhisa Murai, Naoki Higuchi, Kentaro Hoshi, Yukari Fukutoku, Hiroto Hiraga, Kenroh Sasaki, Shinsaku Fukuda

    Biochemistry and biophysics reports   30   101272 - 101272   2022.7

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  • Elucidation of the inhibitory effect of (+)-hopeaphenol on polyinosinic-polycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells.

    Liu Xu, Zaiqiang Yu, Yoshinori Uekusa, Shogo Kawaguchi, Haruhisa Kikuchi, Kazuyuki Daitoku, Masahito Minakawa, Shigeru Motomura, Ken-Ichi Furukawa, Yoshiteru Oshima, Kazuhiko Seya, Tadaatsu Imaizumi

    Journal of pharmacological sciences   149 ( 3 )   147 - 157   2022.7

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  • Tacrolimus Up-regulates Expression of TGFβ Receptor Type II via ERK, Providing Protection Against Intestinal Epithelial Injury.

    Miwa Satake, Hirotake Sakuraba, Hiroto Hiraga, Shukuko Yoshida, Yui Akemoto, Shinji Ota, Yasuhisa Murai, Keisuke Hasui, Shogo Kawaguchi, Hidezumi Kikuchi, Shinsaku Fukuda

    In vivo (Athens, Greece)   36 ( 4 )   1684 - 1693   2022.7

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  • Tryptanthrin attenuates TLR3-mediated STAT1 activation in THP-1 cells

    Noriyuki Numao, Shogo Kawaguchi, Jiangli Ding, Takao Karasawa, Kazuhiko Seya, Tomoh Matsumiya, Hidezumi Kikuchi, Hirotake Sakuraba, Shinsaku Fukuda, Tadaatsu Imaizumi

    Immunologic Research   70 ( 5 )   688 - 697   2022.6

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  • Long-term efficacy and tolerability of dose-adjusted thiopurine treatment in maintaining remission in inflammatory bowel disease patients with NUDT15 heterozygosity

    Takato Maeda, Hirotake Sakuraba, Hiroto Hiraga, Shukuko Yoshida, Yoichi Kakuta, Hidezumi Kikuchi, Shogo Kawaguchi, Keisuke Hasui, Tetsuya Tatsuta, Daisuke Chinda, Tatsuya Mikami, Shinsaku Fukuda

    Intestinal Research   20 ( 1 )   90 - 100   2022.1

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  • Effect of sera from lupus patients on the glomerular endothelial fibrinolysis system.

    Riko Sato, Tomomi Aizawa, Tadaatsu Imaizumi, Koji Tsugawa, Shogo Kawaguchi, Kazuhiko Seya, Kiminori Terui, Hiroshi Tanaka

    Pediatrics international : official journal of the Japan Pediatric Society   64 ( 1 )   e15099   2022.1

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  • Evaluation of metabolic dysfunction-associated fatty liver disease using FibroScan, diet, and microbiota: A large cross-sectional study.

    Tateda T, Iino C, Sasada T, Sato S, Igarashi G, Kawaguchi S, Mikami K, Endo T, Sawada K, Mikami T, Fukuda S, Nakaji S, Sakuraba H

    PloS one   17 ( 11 )   e0277930   2022

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  • Expression of Zinc-Finger Antiviral Protein in hCMEC/D3 Human Cerebral Microvascular Endothelial Cells: Effect of a Toll-Like Receptor 3 Agonist

    M Okudera, M Odawara, M Arakawa, S Kawaguchi, K Seya, T Matsumiya, R Sato, J Ding, E Morita, T Imaizumi

    Neuroimmunomodulation   29 ( 4 )   1 - 10   2021.12

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  • Inhibitory effect of anti-malarial agents on the expression of proinflammatory chemokines via Toll-like receptor 3 signaling in human glomerular endothelial cells.

    Riko Sato, Tadaatsu Imaizumi, Tomomi Aizawa, Shojiro Watanabe, Koji Tsugawa, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Hiroshi Tanaka

    Renal failure   43 ( 1 )   643 - 650   2021.12

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  • 特集 炎症性腸疾患の分子標的治療を総括する Ⅳ.接着分子阻害薬─ ベドリズマブの特性を生かしたIBD 治療

    INTESTINE   25 ( 3 )   267 - 274   2021.9

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  • Hepatic Macrophages Express Melanoma Differentiation-Associated Gene 5 in Nonalcoholic Steatohepatitis

    S Kawaguchi, H Sakuraba, M Horiuchi, J Ding, T Matsumiya, K Seya, C Iino, T Endo, H Kikuchi, S Yoshida, H Hiraga, S Fukuda, T Imaizumi

    Inflammation   45 ( 1 )   343 - 355   2021.9

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  • Expression of IFN-induced transmembrane protein 1 in glomerular endothelial cells.

    Shun Hashimoto, Tadaatsu Imaizumi, Shojiro Watanabe, Tomomi Aizawa, Koji Tsugawa, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Hiroshi Tanaka

    Pediatrics international : official journal of the Japan Pediatric Society   63 ( 9 )   1075 - 1081   2021.9

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  • Daily Brazilian green propolis intake elevates blood artepillin C levels in humans.

    Jiangli Ding, Tomoh Matsumiya, Ryo Hayakari, Yuko Shiba, Shogo Kawaguchi, Kazuhiko Seya, Kayo Ueno, Tadaatsu Imaizumi

    Journal of the science of food and agriculture   101 ( 11 )   4855 - 4861   2021.8

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  • Porphyromonas gingivalis lipopolysaccharide induces interleukin-6 and c-c motif chemokine ligand 2 expression in cultured hCMEC/D3 human brain microvascular endothelial cells.

    Natsu Sato, Takeshi Matsumoto, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Jiangli Ding, Tomomi Aizawa, Tadaatsu Imaizumi

    Gerodontology   39 ( 2 )   139 - 147   2021.2

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  • Tryptanthrin suppresses double-stranded RNA-induced CXCL10 expression via inhibiting the phosphorylation of STAT1 in human umbilical vein endothelial cells

    Shogo Kawaguchi, Hirotake Sakuraba, Hidezumi Kikuchi, et al.

    Molecular Immunology   2021.1

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  • Role of MDA5 in regulating CXCL10 expression induced by TLR3 signaling in human rheumatoid fibroblast-like synoviocytes.

    Tatsuro Saruga, Tadaatsu Imaizumi, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Eiji Sasaki, Norihiro Sasaki, Ryoko Uesato, Yasuyuki Ishibashi

    Molecular biology reports   48 ( 1 )   425 - 433   2021.1

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  • Interleukin-6 via Toll-Like Receptor 3 Signaling Attenuates the Expression of Proinflammatory Chemokines in Human Podocytes.

    Hidenori Umetsu, Shojiro Watanabe, Tadaatsu Imaizumi, Tomomi Aizawa, Koji Tsugawa, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Hiroshi Tanaka

    Kidney & blood pressure research   46 ( 2 )   207 - 218   2021

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  • IFIT Proteins Are Involved in CXCL10 Expression in Human Glomerular Endothelial Cells Treated with a Toll-Like Receptor 3 Agonist.

    Tadaatsu Imaizumi, Shun Hashimoto, Riko Sato, Hidenori Umetsu, Tomomi Aizawa, Shojiro Watanabe, Shogo Kawaguchi, Tomoh Matsumiya, Kazuhiko Seya, Jiangli Ding, Hiroshi Tanaka

    Kidney & blood pressure research   46 ( 1 )   74 - 83   2021

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  • ISG56 is involved in CXCL10 expression induced by TLR3 signaling in BEAS-2B bronchial epithelial cells.

    Toshihiro Shiratori, Tadaatsu Imaizumi, Koji Hirono, Shogo Kawaguchi, Tomoh Matsumiya, Kazuhiko Seya, Sadatomo Tasaka

    Experimental lung research   46 ( 6 )   195 - 202   2020.5

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  • Polyinosinic-Polycytidylic Acid Induces CXCL1 Expression in Cultured hCMEC/D3 Human Cerebral Microvascular Endothelial Cells.

    Yuchen Li, Tadaatsu Imaizumi, Tomoh Matsumiya, Kazuhiko Seya, Shogo Kawaguchi, Jiangli Ding, Hiroki Ohkuma

    Neuroimmunomodulation   27 ( 1 )   38 - 47   2020

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  • Interferon-induced transmembrane protein 1 and Myxovirus resistance protein 1 are induced by polyinosinic-polycytidylic acid in cultured hCMEC/D3 human cerebral microvascular endothelial cells.

    Tadaatsu Imaizumi, Urara Satake, Ruri Miyashita, Shogo Kawaguchi, Tomoh Matsumiya, Kazuhiko Seya, Jiangli Ding, Hiroshi Tanaka

    Journal of neuroimmunology   337   577047 - 577047   2019.12

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  • Melanoma Differentiation-Associated Gene 5 Positively Modulates TNF-α-Induced CXCL10 Expression in Cultured HuH-7 and HLE Cells.

    Shogo Kawaguchi, Hirotake Sakuraba, Toshihiro Haga, Tomoh Matsumiya, Kazuhiko Seya, Tetsu Endo, Naoya Sawada, Chikara Iino, Hidezumi Kikuchi, Hiroto Hiraga, Shinsaku Fukuda, Tadaatsu Imaizumi

    Inflammation   42 ( 6 )   2095 - 2104   2019.12

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  • Endothelial expression of fractalkine (CX3CL1) is induced by Toll-like receptor 3 signaling in cultured human glomerular endothelial cells.

    Koji Hirono, Tadaatsu Imaizumi, Tomomi Aizawa, Shojiro Watanabe, Koji Tsugawa, Toshihiro Shiratori, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Etsuro Ito, Hiroshi Tanaka

    Modern rheumatology   1 - 8   2019.11

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  • 〈一般演題抄録〉一本鎖RNA ウイルスのゲノムRNA 分解機構解明へ向けた基礎検討

    木村 紗也佳, 松宮 朋穂, 吉田 秀見, 瀬谷 和彦, 川口 章吾, 今泉 忠淳

    弘前医学   69 ( 1-4 )   207   2019.3

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  • 〈一般演題抄録〉胆道閉鎖症におけるウイルス感染の関与に関する分子生物学的検討

    木村 俊郎, 今泉 忠淳, 吉田 秀見, 松宮 朋穂, 瀬谷 和彦, 川口 章吾, 早狩 亮, 島田 拓, 吉田 達哉, 小林 完, 平林 健, 袴田 健一

    弘前医学   69 ( 1-4 )   201   2019.3

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  • Cytosolic Sensors of Viral RNA Are Involved in the Production of Interleukin-6 via Toll-Like Receptor 3 Signaling in Human Glomerular Endothelial Cells.

    Qiang Liu, Tadaatsu Imaizumi, Tomomi Aizawa, Koji Hirono, Shogo Kawaguchi, Shojiro Watanabe, Koji Tsugawa, Tomoh Matsumiya, Kazuhiko Seya, Hidemi Yoshida, Hiroshi Tanaka

    Kidney & blood pressure research   44 ( 1 )   62 - 71   2019

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  • Effect of low-concentration amyloid-β 1–42 (Aβ42) on human neuroblastoma SH-SY5Y cell viability: neuroprotective potential of combination use with carnosic acid, rebamipide, edaravone, and resveratrol

    Yoshida Hidemi, Hashimoto Yuko, Fukushima Takashi, Tanji Kunikazu, Matsumiya Tomoh, Seya Kazuhiko, Kawaguchi Shogo, Imaizumi Tadaatsu

    Hirosaki Medical Journal   70 ( 1 )   24 - 38   2019

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  • Retinoic Acid‐inducible Gene‐I and CXCL10 are Involved in Biliary Atresia

    Kimura Toshiro, Imaizumi Tadaatsu, Yoshida Tatsuya, Shimada Taku, Hayakari Ryo, Kawaguchi Shogo, Yoshida Hidemi, Kobayashi Tamotsu, Hirabayashi Takeshi, Mizukami Hiroki, Kijima Hiroshi, Hakamada Kenichi

    Hirosaki Medical Journal   69 ( 1 )   86 - 94   2019

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  • Gastric Focal Neutrophil Infiltration and Wide Duodenal Gastric Foveolar Metaplasia Are Histologic Discriminative Markers for Crohn's Disease and Behçet's Disease.

    Yui Akemoto, Hirotake Sakuraba, Masanori Tanaka, Hiroto Hiraga, Hidezumi Kikuchi, Satoko Morohashi, Shinji Ota, Keisuke Hasui, Miwa Satake, Rina Watanabe, Nahoko Tanaka, Shogo Kawaguchi, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Yoh Ishiguro, Hiroshi Kijima, Shinsaku Fukuda

    Digestion   100 ( 3 )   210 - 219   2019

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  • Interferon-stimulated gene 60 (ISG60) constitutes a negative feedback loop in the downstream of TLR3 signaling in hCMEC/D3 cells

    Imaizumi T, Sassa N, Kawaguchi S, et al.

    Journal of Neuroimmunology   2018.9

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  • The Essential Role of Double-Stranded RNA-Dependent Antiviral Signaling in the Degradation of Nonself Single-Stranded RNA in Nonimmune Cells.

    Kimura S, Matsumiya T, Shiba Y, Nakanishi M, Hayakari R, Kawaguchi S, Yoshida H, Imaizumi T

    Journal of immunology (Baltimore, Md. : 1950)   201 ( 3 )   1044 - 1052   2018.8

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  • Gnetin C suppress double-stranded RNA-induced C-C motif chemokine ligand 2 (CCL2) and CCL5 production by inhibiting Toll-like receptor 3 signaling pathway

    Yoshida H, Imaizumi T, Matsumiya T, et al.

    Biomedical Research   2018.7

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  • The essential role of double-stranded RNA-dependent antiviral signaling in the degeneration of nonself single-stranded RNA in nonimmune cells

    Kimura S, Matsumiya T, Shiba Y, et al.

    Journal of Immunology   2018.6

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  • Toll-like receptor 3 signaling contributes to regional neutrophil recruitment in cultured human glomerular endothelial cells

    Liu Q, Imaizumi T, Kawaguchi S, et al.

    Nephron   2018.5

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  • Gnetin C, a resveratol dimer, reduces amyloid-beta 1-42 production and ameliorates Abeta42-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells

    Seino S, Kimoto T, Yoshida H, et al.

    Biomedical Research   2018.3

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  • Vimentin-positive gastric adenocarcinoma arising in a hyperplastic polyp

    Shogo Kawaguchi, Tetsuro Yoshimura, Hirotake Sakuraba, et al.

    Clinical Journal of Gastroenterology   2018.2

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  • <b>Gnetin C suppresses double-stranded RNA-induced C-C motif chemokine ligand 2 (CCL2) and CCL5 production by inhibiting Toll-like receptor 3 signaling </b><b>pathway </b>

    YOSHIDA Hidemi, IMAIZUMI Tadaatsu, MATSUMIYA Tomoh, SEYA Kazuhiko, KAWAGUCHI Shogo, TANAKA Hiroshi

    Biomedical Research   39 ( 5 )   231 - 240   2018

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  • A CASE OF REFRACTORY BULLOUS PEMPHIGOID IN WHICH THE DOSE OF STEROID COULD BE TAPERED AFTER ENDOSCOPIC SUBMUCOSAL DISSECTION OF EARLY GASTRIC CANCER

    ARAKI Yasumitsu, YOSHIMURA Tetsuro, ASARI Taka, KIKUCHI Koji, KAWAGUCHI Shogo, WADA Toyohito, KUSUMI Tomomi, FUKUDA Shinsaku

    GASTROENTEROLOGICAL ENDOSCOPY   60 ( 1 )   21 - 26   2018

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  • Estimation of perioperative invasiveness of colorectal endoscopic submucosal dissection evaluated by energy metabolism

    Chinda Daisuke, Kawaguchi Shogo, Kikuchi Hidezumi, Hiraga Hiroto, Sawaya Manabu, Sakuraba Hirotake, Mikami Tatsuya, Fukuda Shinsaku, Shimoyama Tadashi, Miyazawa Kuniaki, Arai Tetsu, Hayamizu Shiro, Yanagimachi Miyuki, Tsukamoto Toshiaki, Akitaya Kazuki, Tatsuta Tetsuya

    Journal of Clinical Biochemistry and Nutrition   63 ( 2 )   164 - 167   2018

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  • <b>Gnetin C, a resveratrol dimer, reduces amyloid-β 1–42 (Aβ42) production and ameliorates Aβ42-lowered cell viability in cultured SH-SY5Y human neuroblastoma </b><b>cells </b>

    SEINO Syota, TANAKA Hiroshi, IMAIZUMI Tadaatsu, KIMOTO Takeru, YOSHIDA Hidemi, TANJI Kunikazu, MATSUMIYA Tomoh, HAYAKARI Ryo, SEYA Kazuhiko, KAWAGUCHI Shogo, TSURUGA Kazushi

    Biomedical Research   39 ( 3 )   105 - 115   2018

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  • Expression of CCL5 is induced by polyinosinic : polycytidylic acid in cultured hCMEC/D3 human brain microvascular endothelial cells

    Akine Arai, Hidemi Yoshida, Ryo Hayakari, Tomoh Matsumiya, Shogo Kawaguchi, Kazuhiko Seya, Hiroshi Tanaka, Tadaatsu Imaizumi

    Clinical and Experimental Neuroimmunology   8 ( 4 )   331 - 340   2017.11

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  • Chloroquine attenuates TLR3/IFN-β signaling in cultured normal human mesangial cells: A possible protective effect against renal damage in lupus nephritis.

    Imaizumi T, Hayakari R, Matsumiya T, Yoshida H, Tsuruga K, Watanabe S, Kawaguchi S, Tanaka H

    Modern rheumatology   27 ( 6 )   1004 - 1009   2017.11

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  • Cylindromatosis (CYLD), a Deubiquitinase, Attenuates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells.

    Imaizumi T, Hayakari R, Watanabe S, Aizawa T, Matsumiya T, Yoshida H, Tsuruga K, Kawaguchi S, Tanaka H

    Kidney & blood pressure research   42 ( 5 )   942 - 950   2017

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  • A CASE OF EPSTEIN-BARR VIRUS-POSITIVE INTESTINAL LYMPHOMA AFTER CHEMORADIATION THERAPY FOR PRIMARY THYROID LYMPHOMA

    WATANABE Rina, FUKUDA Shinsaku, KAWAGUCHI Shogo, YOSHIMURA Tetsuro, ASARI Taka, SAWADA Yohei, ARAKI Yasumitsu, KIKUCHI Koji, WADA Toyohito, KUSUMI Tomomi

    GASTROENTEROLOGICAL ENDOSCOPY   59 ( 2 )   171 - 176   2017

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  • Interferon-stimulated gene (ISG) 60, as well as ISG56 and ISG54, positively regulates TLR3/IFN-β/STAT1 axis in U373MG human astrocytoma cells.

    Imaizumi T, Yoshida H, Hayakari R, Xing F, Wang L, Matsumiya T, Tanji K, Kawaguchi S, Murakami M, Tanaka H

    Neuroscience research   105   35 - 41   2016.4

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  • Alteration of Antiviral Signalling by Single Nucleotide Polymorphisms (SNPs) of Mitochondrial Antiviral Signalling Protein (MAVS).

    Xing F, Matsumiya T, Hayakari R, Yoshida H, Kawaguchi S, Takahashi I, Nakaji S, Imaizumi T

    PloS one   11 ( 3 )   e0151173   2016

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  • Interferon-Stimulated Gene 15, a Type I Interferon-Dependent Transcript, Is Involved in a Negative Feedback Loop in Innate Immune Reactions in Human Mesangial Cells.

    Imaizumi T, Shimada T, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Kawaguchi S, Murakami M, Joh K, Tanaka H

    Nephron   132 ( 2 )   144 - 52   2016

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  • Interferon (IFN)-Induced Protein 35 (IFI35), a Type I Interferon-Dependent Transcript, Upregulates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells.

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    Kidney & blood pressure research   41 ( 5 )   635 - 642   2016

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  • Desferrioxamine, An Iron Chelator, Induces CXCL8 Expression in U373MG Human Astrocytoma Cells

    Onda Kaoru, Yoshida Hidemi, Hayakari Ryo, Xing Fei, Wang Lian, Matsumiya Tomoh, Kawaguchi Shogo, Murakami Manabu, Imaizumi Tadaatsu

    弘前医学   66 ( 2 )   127 - 134   2016

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  • Toll-like receptor 3 signaling contributes to the expression of a neutrophil chemoattractant, CXCL1 in human mesangial cells.

    Imaizumi T, Aizawa T, Segawa C, Shimada M, Tsuruga K, Kawaguchi S, Matsumiya T, Yoshida H, Joh K, Tanaka H

    Clinical and experimental nephrology   19 ( 5 )   761 - 70   2015.10

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  • Carnosic acid attenuates apoptosis induced by amyloid-β 1-42 or 1-43 in SH-SY5Y human neuroblastoma cells.

    Meng P, Yoshida H, Tanji K, Matsumiya T, Xing F, Hayakari R, Wang L, Tsuruga K, Tanaka H, Mimura J, Kosaka K, Itoh K, Takahashi I, Kawaguchi S, Imaizumi T

    Neuroscience research   94   1 - 9   2015.5

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  • Desferrioxamine, an iron chelator, inhibits CXCL10 expression induced by polyinosinic-polycytidylic acid in U373MG human astrocytoma cells.

    Imaizumi T, Sakashita N, Mushiga Y, Yoshida H, Hayakari R, Xing F, Wang L, Matsumiya T, Tanji K, Chiba Y, Furudate K, Kawaguchi S, Murakami M, Tanaka H

    Neuroscience research   94   10 - 6   2015.5

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  • A CASE OF FOLLICULAR LYMPHOMA OF THE JEJUNUM WITH INTESTINAL BLEEDING

    KAWAGUCHI Shogo, YOSHIMURA Tetsuro, CHIBA Hiroki, WADA Toyohito, HAYAMIZU Shiro, IKENAGA Shojiro-Kazunori, KUSUMI Tomomi, FUKUDA Shinsaku

    GASTROENTEROLOGICAL ENDOSCOPY   56 ( 6 )   1974 - 1979   2014

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  • A CASE OF A DUODENAL SOMATOSTATINOMA ASSOCIATED WITH VON RECKLINGHAUSEN'S DISEASE

    KAWAGUCHI Shogo, YAMAGATA Ryo, TAKAHASHI Seiji, SAITO Taro, MURATA Yuhji, YAGIHASHI Soroku, FUKUDA Shinsaku

    GASTROENTEROLOGICAL ENDOSCOPY   53 ( 5 )   1435 - 1440   2011.5

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  • Interferon-alpha2b induces p21cip1/waf1 degradation and cell proliferation in HeLa cells.

    Ota K, Matsumiya T, Sakuraba H, Imaizumi T, Yoshida H, Kawaguchi S, Fukuda S, Satoh K

    Cell cycle (Georgetown, Tex.)   9 ( 1 )   131 - 9   2010.1

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  • Cyclosporine regulates intestinal epithelial apoptosis via TGF-beta-related signaling.

    Satoh Y, Ishiguro Y, Sakuraba H, Kawaguchi S, Hiraga H, Fukuda S, Nakane A

    American journal of physiology. Gastrointestinal and liver physiology   297 ( 3 )   G514 - 9   2009.9

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  • Retinoic acid-inducible gene-I is constitutively expressed and involved in IFN-gamma-stimulated CXCL9-11 production in intestinal epithelial cells.

    Kawaguchi S, Ishiguro Y, Imaizumi T, Mori F, Matsumiya T, Yoshida H, Ota K, Sakuraba H, Yamagata K, Sato Y, Tanji K, Haga T, Wakabayashi K, Fukuda S, Satoh K

    Immunology letters   123 ( 1 )   9 - 13   2009.3

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  • Transforming growth factor (TGF)-β receptors are suppressed in the refractory cases with ulcerative colitis

    Shimaya Koji, Ishiguro Yoh, Kawaguchi Shogo, Sato Yuki, Hiraga Hiroto, Yamaguchi Satoko, Sakuraba Hirotake, Fujita Hitoshi, Yamagata Kazufumi, Fukuda Shinsaku

    Hirosaki medical journal   59 ( 2 )   90 - 97   2008

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  • [A case of pneumatosis cystoides intestinalis and intestinal pseudo-obstruction in overlap syndrome manifested by polymyositis and scleroderma].

    Sawamura N, Ishiguro Y, Yamagata K, Kawaguchi S, Yoshimura T, Mikami T, Sasaki Y, Fukuda S, Munakata A

    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology   102 ( 6 )   706 - 11   2005.6

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  • A case of Pneumatosis cystoides intestinalis and intestinal pseudo-obstruction in overlap syndrome manifested by polymyositis and scleroderma

    SAWAMURA Noriko, ISHIGURO Yoh, YAMAGATA Kazufumi, KAWAGUCHI Shogo, YOSHIMURA Tetsuro, MIKAMI Tatsuya, SASAKI Yoshihiro, FUKUDA Shinsaku, MUNAKATA Akihiro

    Nippon Shokakibyo Gakkai Zasshi   102 ( 6 )   706 - 711   2005

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Review Papers

  • 【炎症性腸疾患の分子標的治療を総括する】接着分子阻害薬 ベドリズマブの特性を生かしたIBD治療

    櫻庭 裕丈, 平賀 寛人, 蓮井 桂介, 菊池 英純, 村井 康久, 川口 章吾, 樋口 直樹, 明本 由衣, 福田 眞作

    Intestine   25 ( 3 )   267 - 274   2021.9

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  • 【肺高血圧症の臨床における最新薬物治療】膠原病専門医が診る肺高血圧症 多発性筋炎にともなう間質性肺炎に併存した肺高血圧症の1例

    櫻庭 裕丈, 石黒 陽, 川口 章吾, 佐藤 裕紀, 五十嵐 崇徳, 飯野 勢, 蓮井 桂介, 木村 正臣, 奥村 謙, 福田 眞作

    Modern Physician   30 ( 臨時増刊号 )   42 - 45   2010.10

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  • 消化管上皮細胞の機能分子とその解析法(第13回) 腸管上皮細胞におけるRIG-Iの発現とその解析法

    川口 章吾, 今泉 忠淳, 櫻庭 裕丈, 石黒 陽, 福田 眞作

    分子消化器病   7 ( 1 )   61 - 64   2010.3

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  • 【他領域疾患と消化管疾患】膠原病・アレルギー疾患領域と消化管疾患 皮膚筋炎、全身性硬化症、MCTDにおける消化管障害

    石黒 陽, 櫻庭 裕丈, 樋口 博之, 川口 章吾, 福田 眞作

    臨床消化器内科   24 ( 7 )   887 - 898   2009.5

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  • Trousseau症候群を来した胃癌の1例

    川口 章吾, 石黒 敦, 鈴木 一広, 花田 直之, 高畑 武功, 伊東 重豪, 谷口 啓, 福田 眞作

    癌と化学療法   36 ( 2 )   317 - 320   2009.2

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  • 【炎症性腸疾患の治療をどう行うか QOLからみた治療法の選び方】潰瘍性大腸炎 薬物療法を選択する時(5-ASA/ステロイド/免疫抑制剤など)

    山形 和史, 石黒 陽, 櫻庭 裕丈, 川口 章吾, 佐藤 裕紀, 福田 眞作, 棟方 昭博

    消化器の臨床   10 ( 6 )   565 - 572   2007.12

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  • 【潰瘍性大腸炎・クローン病へのアプローチ 診断と治療の最前線】治療の進歩 潰瘍性大腸炎、クローン病の治療指針

    山形 和史, 石黒 陽, 川口 章吾, 棟方 昭博

    Modern Physician   26 ( 9 )   1454 - 1459   2006.9

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