Papers - KAWAGUCHI Shogo
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Ruxolitinib reverses systemic vasculitis driven by JAK2 V617F–mutated essential thrombocythemia: a case report
Yutaro Ashida, Shinji Ota, Nao Ishidoya, Yasuhisa Murai, Kyoko Amenomori, Keisuke Hasui, Shogo Kawaguchi, Satoko Yamaguchi, Hiroto Hiraga, Kosuke Kamata, Hiroaki Ichikawa, Hirofumi Tomita, Zaiqiang Yu, Masahito Minakawa, Hirotake Sakuraba
Frontiers in Immunology 2026.3
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Negative Regulator of Interferon Response Promotes Toll-like Receptor 3-induced Interleukin 6 in Rheumatoid Synoviocyte.
Wada K, Imaizumi T, Ishibashi HK, Nakamura Y, Saruga T, Kawaguchi S, Tachizaki M, Oishi K, Sasaki E, Wada K, Ishibashi Y
In vivo (Athens, Greece) 40 ( 2 ) 856 - 864 2026.3
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Tripartite motif 22 (TRIM22) downregulates TLR3-induced CCL5 expression in human renal proximal tubular epithelial cells
Mayuki Tachizaki, Yuri Kobori, Shogo Kawaguchi, Kazuhiko Seya, Hiroshi Tanaka, Tadaatsu Imaizumi
Molecular Biology Reports 52 ( 1 ) 306 2025.12
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Tripartite Motif-containing 22 Is Involved in TLR3-mediated Inflammatory Pathway in Rheumatoid Fibroblast-like Synoviocytes
KAIRO WADA, HIKARU KRISTI ISHIBASHI, YUZURU NAKAMURA, TATSURO SARUGA, TADAATSU IMAIZUMI, AKIRA KUROSE, MAYUKI TACHIZAKI, SHOGO KAWAGUCHI, KAZUHIKO SEYA, KAZUKI OISHI, EIJI SASAKI, KANICHIRO WADA, YASUYUKI ISHIBASHI
In Vivo 39 ( 6 ) 3236 - 3246 2025.11
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Heat-killed <i>Lactococcus lactis</i> subsp. <i>lactis</i> L8 ameliorates dextran sulfate sodium-induced colitis in mice
Kawaguchi Shogo, Chinda Daisuke, Ota Shinji, Tonouchi Akio, Maeda Hayato, Miura Kazuhide, Soma Go, Hiraga Hiroto, Ueno Kayo, Niioka Takenori, Tachizaki Mayuki, Seya Kazuhiko, Imaizumi Tadaatsu, Fukuda Shinsaku, Sakuraba Hirotake
Journal of Clinical Biochemistry and Nutrition advpub ( 0 ) 2025.2
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Evaluation of the introduction effects of image-enhanced endoscopic observation and lesion detection AI systems in endoscopic gastric cancer screening
CHINDA Daisuke, KAWAGUCHI Shogo, YASUDA Kohei, FUJIWARA Sae, OZAKI Misa, SASAKI Satoshi, SHIMOYAMA Tadashi
Nihon Shoukaki Gan Kenshin Gakkai zasshi 63 ( 5 ) 652 - 660 2025
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Role of CD34 in calcification of human aortic valve interstitial cells from patients with aortic valve stenosis.
Men S, Yu Z, Liu X, Daitoku K, Tachizaki M, Kawaguchi S, Imaizumi T, Minakawa M, Seya K
Journal of pharmacological sciences 156 ( 3 ) 198 - 207 2024.11
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増大号 炎症性腸疾患2024 主題 炎症性腸疾患の長期経過 潰瘍性大腸炎の長期予後
蓮井 桂介, 平賀 寛人, 太田 真二, 浅利 享, 澤田 洋平, 立田 哲也, 川口 章吾, 菊池 英純, 珍田 大輔, 明本 由衣, 坂本 義之, 袴田 健一, 福田 眞作, 櫻庭 裕丈
胃と腸 59 ( 10 ) 1521 - 1530 2024.10
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Cylindromatosis lysine 63 deubiquitinase (CYLD) suppress TLR3-mediated CCL5 expression in human renal proximal tubular epithelial cells.
Tachizaki M, Kobori Y, Kawaguchi S, Seya K, Tanaka H, Imaizumi T
Molecular biology reports 51 ( 1 ) 974 2024.9
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Expression of ISG60 is induced by TLR3 signaling in BEAS‑2B bronchial epithelial cells: Possible involvement in CXCL10 expression.
Tanaka Y, Imaizumi T, Kobori Y, Tachizaki M, Shiratori T, Dobashi M, Sato M, Kawaguchi S, Seya K, Tasaka S
Molecular medicine reports 30 ( 3 ) 2024.9
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Toll-Like Receptor 7-Expressed Macrophages Are Involved in the Pathogenesis of Esophageal Achalasia and Esophagogastric Junction Outflow Obstruction.
Kaizuka M, Tatsuta T, Kawaguchi S, Yoshizawa T, Yoshida S, Tateda T, Sawada Y, Ota S, Hayamizu S, Hasui K, Kikuchi H, Hiraga H, Chinda D, Muroya T, Hakamada K, Kijima H, Mikami T, Fukuda S, Sakuraba H
Digestion 1 - 12 2024.8
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Interferon‐stimulated gene 56 positively regulates Toll‐like receptor 3‐mediated <scp>CXCL</scp>10 expression in human renal proximal tubular epithelial cells
Mayuki Tachizaki, Sho Sakamoto, Yuri Kobori, Yoshiya Asano, Shogo Kawaguchi, Kazuhiko Seya, Hiroshi Tanaka, Eiji Morita, Tadaatsu Imaizumi
FEBS Open Bio 14 ( 8 ) 1303 - 1319 2024.6
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Resiquimod Induces C-C Motif Chemokine Ligand 2 Via Nuclear Factor-Kappa B in SH-SY5Y Human Neuroblastoma Cells.
Masatoshi Kaizuka, Shogo Kawaguchi, Tetsuya Tatsuta, Mayuki Tachizaki, Yuri Kobori, Yusuke Tanaka, Kazuhiko Seya, Tomoh Matsumiya, Tadaatsu Imaizumi, Hirotake Sakuraba
Neuromolecular medicine 26 ( 1 ) 16 - 16 2024.4
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Diamidobenzimidazole, an agonist of STING, induces the expression of retinoic acid-inducible gene-I and interferon-induced transmembrane protein 1 in BEAS-2B cells
Sato Mami, Imaizumi Tadaatsu, Ding Jiangli, Seya Kazuhiko, Kawaguchi Shogo, Tanaka Yusuke, Matsuzaki Yasushi, Matsumiya Tomoh, Matsubara Atsushi
Hirosaki Medical Journal 74 ( 1-4 ) 117 - 127 2024.3
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TMEM2 suppresses TLR3-mediated IFN-β/ISG56/CXCL10 expression in BEAS-2B bronchial epithelial cells.
Yuri Kobori, Mayuki Tachizaki, Tadaatsu Imaizumi, Yusuke Tanaka, Kazuhiko Seya, Yasuo Miki, Shogo Kawaguchi, Tomoh Matsumiya, Yuki Tobisawa, Chikara Ohyama, Sadatomo Tasaka
Molecular biology reports 51 ( 1 ) 417 - 417 2024.3
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The inhibitory effect of DIF-3 on polyinosinic-polycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells.
Ryusei Araya, Shihu Men, Yoshinori Uekusa, Zaiqiang Yu, Haruhisa Kikuchi, Kazuyuki Daitoku, Masahito Minakawa, Shogo Kawaguchi, Ken-Ichi Furukawa, Yoshiteru Oshima, Tadaatsu Imaizumi, Kazuhiko Seya
Journal of pharmacological sciences 154 ( 3 ) 157 - 165 2024.3
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Possible involvement of DExD/H box helicase 60 in synovial inflammation of rheumatoid arthritis: role of toll-like receptor 3 signaling.
Yuzuru Nakamura, Hikaru Kristi Ishibashi, Tatsuro Saruga, Tadaatsu Imaizumi, Akira Kurose, Mayuki Tachizaki, Shogo Kawaguchi, Kazuhiko Seya, Eiji Sasaki, Yasuyuki Ishibashi
Molecular biology reports 51 ( 1 ) 131 - 131 2024.1
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TLR3 signaling-induced interferon-stimulated gene 56 plays a role in the pathogenesis of rheumatoid arthritis.
Ishibashi HK, Nakamura Y, Saruga T, Imaizumi T, Kurose A, Kawaguchi S, Seya K, Sasaki E, Ishibashi Y
Experimental biology and medicine (Maywood, N.J.) 249 10122 2024
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Expression of interferon-stimulated gene 20 (ISG20), an antiviral effector protein, in glomerular endothelial cells: possible involvement of ISG20 in lupus nephritis.
Takao Karasawa, Riko Sato, Tadaatsu Imaizumi, Masashi Fujita, Tomomi Aizawa, Koji Tsugawa, Deborah Mattinzoli, Shogo Kawaguchi, Kazuhiko Seya, Kiminori Terui, Kensuke Joh, Hiroshi Tanaka
Renal failure 45 ( 1 ) 2224890 - 2224890 2023.12
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Polygonum tinctorium leaf extract ameliorates high-fat diet-induced intestinal epithelial damage in mice.
Shogo Kawaguchi, Hirotake Sakuraba, Hidezumi Kikuchi, Kota Matsuki, Yudai Hayashi, Jiangli Ding, Yusuke Tanaka, Kazuhiko Seya, Tomoh Matsumiya, Hiroto Hiraga, Shinsaku Fukuda, Kenroh Sasaki, Tadaatsu Imaizumi
Experimental and therapeutic medicine 25 ( 3 ) 112 - 112 2023.3
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The double-stranded RNA-dependent protein kinase PKR negatively regulates the protein expression of IFN-β induced by RIG-I signaling.
Tomoh Matsumiya, Yuko Shiba, Jiangli Ding, Shogo Kawaguchi, Kazuhiko Seya, Tadaatsu Imaizumi
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 37 ( 2 ) e22780 2023.2
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ER export signals mediate plasma membrane localization of transmembrane protein TMEM72.
Jiangli Ding, Tomoh Matsumiya, Yasuo Miki, Ryo Hayakari, Yuko Shiba, Shogo Kawaguchi, Kazuhiko Seya, Tadaatsu Imaizumi
The FEBS journal 290 ( 10 ) 2636 - 2657 2022.12
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Glomerular endothelial expression of type I IFN-stimulated gene, DExD/H-Box helicase 60 via toll-like receptor 3 signaling: possible involvement in the pathogenesis of lupus nephritis.
Takao Karasawa, Riko Sato, Tadaatsu Imaizumi, Shun Hashimoto, Masashi Fujita, Tomomi Aizawa, Koji Tsugawa, Shogo Kawaguchi, Kazuhiko Seya, Kiminori Terui, Hiroshi Tanaka
Renal failure 44 ( 1 ) 137 - 145 2022.12
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Toll-like receptor 3 signaling induces interferon-induced transmembrane protein 1 in BEAS-2B cells.
Dobashi M, Shiratori T, Imaizumi T, Hashimoto S, Kawaguchi S, Seya K, Tasaka S
Experimental biology and medicine (Maywood, N.J.) 247 ( 21 ) 1917 - 1922 2022.11
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Polygonum tinctorium leaves suppress sodium dextran sulfate-induced colitis through interleukin-10-related pathway.
Taka Asari, Hidezumi Kikuchi, Shogo Kawaguchi, Hirotake Sakuraba, Shukuko Yoshida, Yui Akemoto, Takato Maeda, Ota Shinji, Yasuhisa Murai, Naoki Higuchi, Kentaro Hoshi, Yukari Fukutoku, Hiroto Hiraga, Kenroh Sasaki, Shinsaku Fukuda
Biochemistry and biophysics reports 30 101272 - 101272 2022.7
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Tacrolimus Up-regulates Expression of TGFβ Receptor Type II via ERK, Providing Protection Against Intestinal Epithelial Injury.
Miwa Satake, Hirotake Sakuraba, Hiroto Hiraga, Shukuko Yoshida, Yui Akemoto, Shinji Ota, Yasuhisa Murai, Keisuke Hasui, Shogo Kawaguchi, Hidezumi Kikuchi, Shinsaku Fukuda
In vivo (Athens, Greece) 36 ( 4 ) 1684 - 1693 2022.7
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Elucidation of the inhibitory effect of (+)-hopeaphenol on polyinosinic-polycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells.
Liu Xu, Zaiqiang Yu, Yoshinori Uekusa, Shogo Kawaguchi, Haruhisa Kikuchi, Kazuyuki Daitoku, Masahito Minakawa, Shigeru Motomura, Ken-Ichi Furukawa, Yoshiteru Oshima, Kazuhiko Seya, Tadaatsu Imaizumi
Journal of pharmacological sciences 149 ( 3 ) 147 - 157 2022.7
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胃原発胎児消化管上皮類似癌に対して内視鏡的粘膜下層剥離術を施行し、術後経過を観察しえた1例
佐藤 諭, 珍田 大輔, 福徳 友香理, 新井 徹, 澤田 洋平, 立田 哲也, 川口 章吾, 菊池 英純, 櫻庭 裕丈, 三上 達也, 吉澤 忠司, 鬼島 宏, 福田 眞作
日本消化器内視鏡学会誌 168回 100 - 100 2022.7
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Tryptanthrin attenuates TLR3-mediated STAT1 activation in THP-1 cells
Noriyuki Numao, Shogo Kawaguchi, Jiangli Ding, Takao Karasawa, Kazuhiko Seya, Tomoh Matsumiya, Hidezumi Kikuchi, Hirotake Sakuraba, Shinsaku Fukuda, Tadaatsu Imaizumi
Immunologic Research 70 ( 5 ) 688 - 697 2022.6
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TMEM72の細胞内局在に関する検討
丁 江麗, 松宮 朋穂, 川口 章吾, 瀬谷 和彦, 今泉 忠淳
弘前医学 72 ( 1-4 ) 102 - 102 2022.3
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Long-term efficacy and tolerability of dose-adjusted thiopurine treatment in maintaining remission in inflammatory bowel disease patients with NUDT15 heterozygosity
Takato Maeda, Hirotake Sakuraba, Hiroto Hiraga, Shukuko Yoshida, Yoichi Kakuta, Hidezumi Kikuchi, Shogo Kawaguchi, Keisuke Hasui, Tetsuya Tatsuta, Daisuke Chinda, Tatsuya Mikami, Shinsaku Fukuda
Intestinal Research 20 ( 1 ) 90 - 100 2022.1
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Effect of sera from lupus patients on the glomerular endothelial fibrinolysis system.
Riko Sato, Tomomi Aizawa, Tadaatsu Imaizumi, Koji Tsugawa, Shogo Kawaguchi, Kazuhiko Seya, Kiminori Terui, Hiroshi Tanaka
Pediatrics international : official journal of the Japan Pediatric Society 64 ( 1 ) e15099 2022.1
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Evaluation of metabolic dysfunction-associated fatty liver disease using FibroScan, diet, and microbiota: A large cross-sectional study
Tetsuyuki Tateda, Chikara Iino, Takafumi Sasada, Satoshi Sato, Go Igarashi, Shogo Kawaguchi, Kenichiro Mikami, Tetsu Endo, Kaori Sawada, Tatsuya Mikami, Shinsaku Fukuda, Shigeyuki Nakaji, Hirotake Sakuraba
PLOS ONE 17 ( 11 ) e0277930 2022
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Expression of Zinc-Finger Antiviral Protein in hCMEC/D3 Human Cerebral Microvascular Endothelial Cells: Effect of a Toll-Like Receptor 3 Agonist
M Okudera, M Odawara, M Arakawa, S Kawaguchi, K Seya, T Matsumiya, R Sato, J Ding, E Morita, T Imaizumi
Neuroimmunomodulation 29 ( 4 ) 1 - 10 2021.12
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Inhibitory effect of anti-malarial agents on the expression of proinflammatory chemokines via Toll-like receptor 3 signaling in human glomerular endothelial cells.
Riko Sato, Tadaatsu Imaizumi, Tomomi Aizawa, Shojiro Watanabe, Koji Tsugawa, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Hiroshi Tanaka
Renal failure 43 ( 1 ) 643 - 650 2021.12
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特集 炎症性腸疾患の分子標的治療を総括する Ⅳ.接着分子阻害薬─ ベドリズマブの特性を生かしたIBD 治療
INTESTINE 25 ( 3 ) 267 - 274 2021.9
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Hepatic Macrophages Express Melanoma Differentiation-Associated Gene 5 in Nonalcoholic Steatohepatitis
S Kawaguchi, H Sakuraba, M Horiuchi, J Ding, T Matsumiya, K Seya, C Iino, T Endo, H Kikuchi, S Yoshida, H Hiraga, S Fukuda, T Imaizumi
Inflammation 45 ( 1 ) 343 - 355 2021.9
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Expression of IFN-induced transmembrane protein 1 in glomerular endothelial cells.
Shun Hashimoto, Tadaatsu Imaizumi, Shojiro Watanabe, Tomomi Aizawa, Koji Tsugawa, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Hiroshi Tanaka
Pediatrics international : official journal of the Japan Pediatric Society 63 ( 9 ) 1075 - 1081 2021.9
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Daily Brazilian green propolis intake elevates blood artepillin C levels in humans.
Jiangli Ding, Tomoh Matsumiya, Ryo Hayakari, Yuko Shiba, Shogo Kawaguchi, Kazuhiko Seya, Kayo Ueno, Tadaatsu Imaizumi
Journal of the science of food and agriculture 101 ( 11 ) 4855 - 4861 2021.8
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Porphyromonas gingivalis lipopolysaccharide induces interleukin-6 and c-c motif chemokine ligand 2 expression in cultured hCMEC/D3 human brain microvascular endothelial cells.
Natsu Sato, Takeshi Matsumoto, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Jiangli Ding, Tomomi Aizawa, Tadaatsu Imaizumi
Gerodontology 39 ( 2 ) 139 - 147 2021.2
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Tryptanthrin suppresses double-stranded RNA-induced CXCL10 expression via inhibiting the phosphorylation of STAT1 in human umbilical vein endothelial cells
Shogo Kawaguchi, Hirotake Sakuraba, Hidezumi Kikuchi, et al.
Molecular Immunology 2021.1
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Role of MDA5 in regulating CXCL10 expression induced by TLR3 signaling in human rheumatoid fibroblast-like synoviocytes.
Tatsuro Saruga, Tadaatsu Imaizumi, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Eiji Sasaki, Norihiro Sasaki, Ryoko Uesato, Yasuyuki Ishibashi
Molecular biology reports 48 ( 1 ) 425 - 433 2021.1
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Interleukin-6 via Toll-Like Receptor 3 Signaling Attenuates the Expression of Proinflammatory Chemokines in Human Podocytes.
Hidenori Umetsu, Shojiro Watanabe, Tadaatsu Imaizumi, Tomomi Aizawa, Koji Tsugawa, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Hiroshi Tanaka
Kidney & blood pressure research 46 ( 2 ) 207 - 218 2021
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IFIT Proteins Are Involved in CXCL10 Expression in Human Glomerular Endothelial Cells Treated with a Toll-Like Receptor 3 Agonist.
Tadaatsu Imaizumi, Shun Hashimoto, Riko Sato, Hidenori Umetsu, Tomomi Aizawa, Shojiro Watanabe, Shogo Kawaguchi, Tomoh Matsumiya, Kazuhiko Seya, Jiangli Ding, Hiroshi Tanaka
Kidney & blood pressure research 46 ( 1 ) 74 - 83 2021
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ISG56 is involved in CXCL10 expression induced by TLR3 signaling in BEAS-2B bronchial epithelial cells.
Toshihiro Shiratori, Tadaatsu Imaizumi, Koji Hirono, Shogo Kawaguchi, Tomoh Matsumiya, Kazuhiko Seya, Sadatomo Tasaka
Experimental lung research 46 ( 6 ) 195 - 202 2020.5
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Polyinosinic-Polycytidylic Acid Induces CXCL1 Expression in Cultured hCMEC/D3 Human Cerebral Microvascular Endothelial Cells.
Yuchen Li, Tadaatsu Imaizumi, Tomoh Matsumiya, Kazuhiko Seya, Shogo Kawaguchi, Jiangli Ding, Hiroki Ohkuma
Neuroimmunomodulation 27 ( 1 ) 38 - 47 2020
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Interferon-induced transmembrane protein 1 and Myxovirus resistance protein 1 are induced by polyinosinic-polycytidylic acid in cultured hCMEC/D3 human cerebral microvascular endothelial cells.
Tadaatsu Imaizumi, Urara Satake, Ruri Miyashita, Shogo Kawaguchi, Tomoh Matsumiya, Kazuhiko Seya, Jiangli Ding, Hiroshi Tanaka
Journal of neuroimmunology 337 577047 - 577047 2019.12
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Melanoma Differentiation-Associated Gene 5 Positively Modulates TNF-α-Induced CXCL10 Expression in Cultured HuH-7 and HLE Cells.
Shogo Kawaguchi, Hirotake Sakuraba, Toshihiro Haga, Tomoh Matsumiya, Kazuhiko Seya, Tetsu Endo, Naoya Sawada, Chikara Iino, Hidezumi Kikuchi, Hiroto Hiraga, Shinsaku Fukuda, Tadaatsu Imaizumi
Inflammation 42 ( 6 ) 2095 - 2104 2019.12
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Endothelial expression of fractalkine (CX3CL1) is induced by Toll-like receptor 3 signaling in cultured human glomerular endothelial cells.
Koji Hirono, Tadaatsu Imaizumi, Tomomi Aizawa, Shojiro Watanabe, Koji Tsugawa, Toshihiro Shiratori, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Etsuro Ito, Hiroshi Tanaka
Modern rheumatology 1 - 8 2019.11
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〈一般演題抄録〉一本鎖RNA ウイルスのゲノムRNA 分解機構解明へ向けた基礎検討
木村 紗也佳, 松宮 朋穂, 吉田 秀見, 瀬谷 和彦, 川口 章吾, 今泉 忠淳
弘前医学 69 ( 1-4 ) 207 2019.3
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〈一般演題抄録〉胆道閉鎖症におけるウイルス感染の関与に関する分子生物学的検討
木村 俊郎, 今泉 忠淳, 吉田 秀見, 松宮 朋穂, 瀬谷 和彦, 川口 章吾, 早狩 亮, 島田 拓, 吉田 達哉, 小林 完, 平林 健, 袴田 健一
弘前医学 69 ( 1-4 ) 201 2019.3
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Cytosolic Sensors of Viral RNA Are Involved in the Production of Interleukin-6 via Toll-Like Receptor 3 Signaling in Human Glomerular Endothelial Cells.
Qiang Liu, Tadaatsu Imaizumi, Tomomi Aizawa, Koji Hirono, Shogo Kawaguchi, Shojiro Watanabe, Koji Tsugawa, Tomoh Matsumiya, Kazuhiko Seya, Hidemi Yoshida, Hiroshi Tanaka
Kidney & blood pressure research 44 ( 1 ) 62 - 71 2019
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Retinoic Acid‐inducible Gene‐I and CXCL10 are Involved in Biliary Atresia
Kimura Toshiro, Imaizumi Tadaatsu, Yoshida Tatsuya, Shimada Taku, Hayakari Ryo, Kawaguchi Shogo, Yoshida Hidemi, Kobayashi Tamotsu, Hirabayashi Takeshi, Mizukami Hiroki, Kijima Hiroshi, Hakamada Kenichi
Hirosaki Medical Journal 69 ( 1 ) 86 - 94 2019
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Gastric Focal Neutrophil Infiltration and Wide Duodenal Gastric Foveolar Metaplasia Are Histologic Discriminative Markers for Crohn's Disease and Behçet's Disease.
Yui Akemoto, Hirotake Sakuraba, Masanori Tanaka, Hiroto Hiraga, Hidezumi Kikuchi, Satoko Morohashi, Shinji Ota, Keisuke Hasui, Miwa Satake, Rina Watanabe, Nahoko Tanaka, Shogo Kawaguchi, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Yoh Ishiguro, Hiroshi Kijima, Shinsaku Fukuda
Digestion 100 ( 3 ) 210 - 219 2019
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Effect of low-concentration amyloid-β 1–42 (Aβ42) on human neuroblastoma SH-SY5Y cell viability: neuroprotective potential of combination use with carnosic acid, rebamipide, edaravone, and resveratrol
Yoshida Hidemi, Hashimoto Yuko, Fukushima Takashi, Tanji Kunikazu, Matsumiya Tomoh, Seya Kazuhiko, Kawaguchi Shogo, Imaizumi Tadaatsu
Hirosaki Medical Journal 70 ( 1 ) 24 - 38 2019
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Induction of C-C motif chemokine ligand 2 through Toll-like receptor 3 signaling in human cerebral microvascular endothelial cell/D3 cells: possible regulation by nuclear factor-κB
Naoko Sassa, Koji Hirono, Toshihiro Shiratori, Shogo Kawaguchi, Tomoh Matsumiya, Hidemi Yoshida, Kazuhiko Seya, Hiroshi Tanaka, Tadaatsu Imaizumi
Clinical and Experimental Neuroimmunology 10 ( 3 ) 197 - 203 2019
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Effect of low-concentration amyloid-p 1-42 (Ap42) on human neuroblastoma SH-SY5Y cell viability: Neuroprotective potential of combination use with carnosic acid, rebamipide, edaravone, and resveratrol
Hidemi Yoshida, Yuko Hashimoto, Takashi Fukushima, Kunikazu Tanji, Tomoh Matsumiya, Kazuhiko Seya, Shogo Kawaguchi, Tadaatsu Imaizumi
Hirosaki Medical Journal 70 ( 1 ) 24 - 38 2019
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Interferon-stimulated gene 60 (ISG60) constitutes a negative feedback loop in the downstream of TLR3 signaling in hCMEC/D3 cells
Imaizumi T, Sassa N, Kawaguchi S, et al.
Journal of Neuroimmunology 2018.9
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The Essential Role of Double-Stranded RNA-Dependent Antiviral Signaling in the Degradation of Nonself Single-Stranded RNA in Nonimmune Cells.
Kimura S, Matsumiya T, Shiba Y, Nakanishi M, Hayakari R, Kawaguchi S, Yoshida H, Imaizumi T
Journal of immunology (Baltimore, Md. : 1950) 201 ( 3 ) 1044 - 1052 2018.8
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Gnetin C suppress double-stranded RNA-induced C-C motif chemokine ligand 2 (CCL2) and CCL5 production by inhibiting Toll-like receptor 3 signaling pathway
Yoshida H, Imaizumi T, Matsumiya T, et al.
Biomedical Research 2018.7
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The essential role of double-stranded RNA-dependent antiviral signaling in the degeneration of nonself single-stranded RNA in nonimmune cells
Kimura S, Matsumiya T, Shiba Y, et al.
Journal of Immunology 2018.6
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Toll-like receptor 3 signaling contributes to regional neutrophil recruitment in cultured human glomerular endothelial cells
Liu Q, Imaizumi T, Kawaguchi S, et al.
Nephron 2018.5
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Gnetin C, a resveratol dimer, reduces amyloid-beta 1-42 production and ameliorates Abeta42-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells
Seino S, Kimoto T, Yoshida H, et al.
Biomedical Research 2018.3
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Vimentin-positive gastric adenocarcinoma arising in a hyperplastic polyp
Shogo Kawaguchi, Tetsuro Yoshimura, Hirotake Sakuraba, et al.
Clinical Journal of Gastroenterology 2018.2
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A CASE OF REFRACTORY BULLOUS PEMPHIGOID IN WHICH THE DOSE OF STEROID COULD BE TAPERED AFTER ENDOSCOPIC SUBMUCOSAL DISSECTION OF EARLY GASTRIC CANCER
ARAKI Yasumitsu, YOSHIMURA Tetsuro, ASARI Taka, KIKUCHI Koji, KAWAGUCHI Shogo, WADA Toyohito, KUSUMI Tomomi, FUKUDA Shinsaku
GASTROENTEROLOGICAL ENDOSCOPY 60 ( 1 ) 21 - 26 2018
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Estimation of perioperative invasiveness of colorectal endoscopic submucosal dissection evaluated by energy metabolism
Chinda Daisuke, Kawaguchi Shogo, Kikuchi Hidezumi, Hiraga Hiroto, Sawaya Manabu, Sakuraba Hirotake, Mikami Tatsuya, Fukuda Shinsaku, Shimoyama Tadashi, Miyazawa Kuniaki, Arai Tetsu, Hayamizu Shiro, Yanagimachi Miyuki, Tsukamoto Toshiaki, Akitaya Kazuki, Tatsuta Tetsuya
Ｊｏｕｒｎａｌ ｏｆ Ｃｌｉｎｉｃａｌ Ｂｉｏｃｈｅｍｉｓｔｒｙ ａｎｄ Ｎｕｔｒｉｔｉｏｎ 63 ( 2 ) 164 - 167 2018
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<b>Gnetin C, a resveratrol dimer, reduces amyloid-β 1–42 (Aβ42) production and ameliorates Aβ42-lowered cell viability in cultured SH-SY5Y human neuroblastoma </b><b>cells </b>
SEINO Syota, TANAKA Hiroshi, IMAIZUMI Tadaatsu, KIMOTO Takeru, YOSHIDA Hidemi, TANJI Kunikazu, MATSUMIYA Tomoh, HAYAKARI Ryo, SEYA Kazuhiko, KAWAGUCHI Shogo, TSURUGA Kazushi
Biomedical Research 39 ( 3 ) 105 - 115 2018
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<b>Gnetin C suppresses double-stranded RNA-induced C-C motif chemokine ligand 2 (CCL2) and CCL5 production by inhibiting Toll-like receptor 3 signaling </b><b>pathway </b>
YOSHIDA Hidemi, IMAIZUMI Tadaatsu, MATSUMIYA Tomoh, SEYA Kazuhiko, KAWAGUCHI Shogo, TANAKA Hiroshi
Biomedical Research 39 ( 5 ) 231 - 240 2018
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Expression of CCL5 is induced by polyinosinic : polycytidylic acid in cultured hCMEC/D3 human brain microvascular endothelial cells
Akine Arai, Hidemi Yoshida, Ryo Hayakari, Tomoh Matsumiya, Shogo Kawaguchi, Kazuhiko Seya, Hiroshi Tanaka, Tadaatsu Imaizumi
Clinical and Experimental Neuroimmunology 8 ( 4 ) 331 - 340 2017.11
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Chloroquine attenuates TLR3/IFN-β signaling in cultured normal human mesangial cells: A possible protective effect against renal damage in lupus nephritis.
Imaizumi T, Hayakari R, Matsumiya T, Yoshida H, Tsuruga K, Watanabe S, Kawaguchi S, Tanaka H
Modern rheumatology 27 ( 6 ) 1004 - 1009 2017.11
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Cylindromatosis (CYLD), a Deubiquitinase, Attenuates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells.
Imaizumi T, Hayakari R, Watanabe S, Aizawa T, Matsumiya T, Yoshida H, Tsuruga K, Kawaguchi S, Tanaka H
Kidney & blood pressure research 42 ( 5 ) 942 - 950 2017
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A CASE OF EPSTEIN-BARR VIRUS-POSITIVE INTESTINAL LYMPHOMA AFTER CHEMORADIATION THERAPY FOR PRIMARY THYROID LYMPHOMA
WATANABE Rina, FUKUDA Shinsaku, KAWAGUCHI Shogo, YOSHIMURA Tetsuro, ASARI Taka, SAWADA Yohei, ARAKI Yasumitsu, KIKUCHI Koji, WADA Toyohito, KUSUMI Tomomi
GASTROENTEROLOGICAL ENDOSCOPY 59 ( 2 ) 171 - 176 2017
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Interferon-stimulated gene (ISG) 60, as well as ISG56 and ISG54, positively regulates TLR3/IFN-β/STAT1 axis in U373MG human astrocytoma cells.
Imaizumi T, Yoshida H, Hayakari R, Xing F, Wang L, Matsumiya T, Tanji K, Kawaguchi S, Murakami M, Tanaka H
Neuroscience research 105 35 - 41 2016.4
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Interferon-Stimulated Gene 15, a Type I Interferon-Dependent Transcript, Is Involved in a Negative Feedback Loop in Innate Immune Reactions in Human Mesangial Cells.
Imaizumi T, Shimada T, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Kawaguchi S, Murakami M, Joh K, Tanaka H
Nephron 132 ( 2 ) 144 - 52 2016
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Interferon (IFN)-Induced Protein 35 (IFI35), a Type I Interferon-Dependent Transcript, Upregulates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells.
Imaizumi T, Yano C, Numata A, Tsugawa K, Hayakari R, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Kawaguchi S, Murakami M, Tanaka H
Kidney & blood pressure research 41 ( 5 ) 635 - 642 2016
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Desferrioxamine, An Iron Chelator, Induces CXCL8 Expression in U373MG Human Astrocytoma Cells
Onda Kaoru, Yoshida Hidemi, Hayakari Ryo, Xing Fei, Wang Lian, Matsumiya Tomoh, Kawaguchi Shogo, Murakami Manabu, Imaizumi Tadaatsu
弘前医学 66 ( 2 ) 127 - 134 2016
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Alteration of Antiviral Signalling by Single Nucleotide Polymorphisms (SNPs) of Mitochondrial Antiviral Signalling Protein (MAVS).
Xing F, Matsumiya T, Hayakari R, Yoshida H, Kawaguchi S, Takahashi I, Nakaji S, Imaizumi T
PloS one 11 ( 3 ) e0151173 2016
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Toll-like receptor 3 signaling contributes to the expression of a neutrophil chemoattractant, CXCL1 in human mesangial cells.
Imaizumi T, Aizawa T, Segawa C, Shimada M, Tsuruga K, Kawaguchi S, Matsumiya T, Yoshida H, Joh K, Tanaka H
Clinical and experimental nephrology 19 ( 5 ) 761 - 70 2015.10
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Carnosic acid attenuates apoptosis induced by amyloid-β 1-42 or 1-43 in SH-SY5Y human neuroblastoma cells.
Meng P, Yoshida H, Tanji K, Matsumiya T, Xing F, Hayakari R, Wang L, Tsuruga K, Tanaka H, Mimura J, Kosaka K, Itoh K, Takahashi I, Kawaguchi S, Imaizumi T
Neuroscience research 94 1 - 9 2015.5
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Desferrioxamine, an iron chelator, inhibits CXCL10 expression induced by polyinosinic-polycytidylic acid in U373MG human astrocytoma cells.
Imaizumi T, Sakashita N, Mushiga Y, Yoshida H, Hayakari R, Xing F, Wang L, Matsumiya T, Tanji K, Chiba Y, Furudate K, Kawaguchi S, Murakami M, Tanaka H
Neuroscience research 94 10 - 6 2015.5
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A CASE OF FOLLICULAR LYMPHOMA OF THE JEJUNUM WITH INTESTINAL BLEEDING
KAWAGUCHI Shogo, YOSHIMURA Tetsuro, CHIBA Hiroki, WADA Toyohito, HAYAMIZU Shiro, IKENAGA Shojiro-Kazunori, KUSUMI Tomomi, FUKUDA Shinsaku
GASTROENTEROLOGICAL ENDOSCOPY 56 ( 6 ) 1974 - 1979 2014
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A CASE OF A DUODENAL SOMATOSTATINOMA ASSOCIATED WITH VON RECKLINGHAUSEN'S DISEASE
KAWAGUCHI Shogo, YAMAGATA Ryo, TAKAHASHI Seiji, SAITO Taro, MURATA Yuhji, YAGIHASHI Soroku, FUKUDA Shinsaku
GASTROENTEROLOGICAL ENDOSCOPY 53 ( 5 ) 1435 - 1440 2011.5
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Interferon-alpha2b induces p21cip1/waf1 degradation and cell proliferation in HeLa cells.
Ota K, Matsumiya T, Sakuraba H, Imaizumi T, Yoshida H, Kawaguchi S, Fukuda S, Satoh K
Cell cycle (Georgetown, Tex.) 9 ( 1 ) 131 - 9 2010.1
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Cyclosporine regulates intestinal epithelial apoptosis via TGF-beta-related signaling.
Satoh Y, Ishiguro Y, Sakuraba H, Kawaguchi S, Hiraga H, Fukuda S, Nakane A
American journal of physiology. Gastrointestinal and liver physiology 297 ( 3 ) G514 - 9 2009.9
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Retinoic acid-inducible gene-I is constitutively expressed and involved in IFN-gamma-stimulated CXCL9-11 production in intestinal epithelial cells.
Kawaguchi S, Ishiguro Y, Imaizumi T, Mori F, Matsumiya T, Yoshida H, Ota K, Sakuraba H, Yamagata K, Sato Y, Tanji K, Haga T, Wakabayashi K, Fukuda S, Satoh K
Immunology letters 123 ( 1 ) 9 - 13 2009.3
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Transforming growth factor (TGF)-β receptors are suppressed in the refractory cases with ulcerative colitis
Shimaya Koji, Ishiguro Yoh, Kawaguchi Shogo, Sato Yuki, Hiraga Hiroto, Yamaguchi Satoko, Sakuraba Hirotake, Fujita Hitoshi, Yamagata Kazufumi, Fukuda Shinsaku
Hirosaki medical journal 59 ( 2 ) 90 - 97 2008
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[A case of pneumatosis cystoides intestinalis and intestinal pseudo-obstruction in overlap syndrome manifested by polymyositis and scleroderma].
Sawamura N, Ishiguro Y, Yamagata K, Kawaguchi S, Yoshimura T, Mikami T, Sasaki Y, Fukuda S, Munakata A
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 102 ( 6 ) 706 - 11 2005.6
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A case of Pneumatosis cystoides intestinalis and intestinal pseudo-obstruction in overlap syndrome manifested by polymyositis and scleroderma
SAWAMURA Noriko, ISHIGURO Yoh, YAMAGATA Kazufumi, KAWAGUCHI Shogo, YOSHIMURA Tetsuro, MIKAMI Tatsuya, SASAKI Yoshihiro, FUKUDA Shinsaku, MUNAKATA Akihiro
Nippon Shokakibyo Gakkai Zasshi 102 ( 6 ) 706 - 711 2005