研究者詳細 - 川口　章吾

論文 - 川口　章吾

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Ruxolitinib reverses systemic vasculitis driven by JAK2 V617F–mutated essential thrombocythemia: a case report

Yutaro Ashida, Shinji Ota, Nao Ishidoya, Yasuhisa Murai, Kyoko Amenomori, Keisuke Hasui, Shogo Kawaguchi, Satoko Yamaguchi, Hiroto Hiraga, Kosuke Kamata, Hiroaki Ichikawa, Hirofumi Tomita, Zaiqiang Yu, Masahito Minakawa, Hirotake Sakuraba

Frontiers in Immunology 2026年03月

Negative Regulator of Interferon Response Promotes Toll-like Receptor 3-induced Interleukin 6 in Rheumatoid Synoviocyte.

Wada K, Imaizumi T, Ishibashi HK, Nakamura Y, Saruga T, Kawaguchi S, Tachizaki M, Oishi K, Sasaki E, Wada K, Ishibashi Y

In vivo (Athens, Greece) 40 ( 2 ) 856 - 864 2026年03月

Tripartite motif 22 (TRIM22) downregulates TLR3-induced CCL5 expression in human renal proximal tubular epithelial cells.

Tachizaki M, Kobori Y, Kawaguchi S, Seya K, Tanaka H, Imaizumi T

Molecular biology reports 52 ( 1 ) 306 2025年12月

Tripartite Motif-containing 22 Is Involved in TLR3-mediated Inflammatory Pathway in Rheumatoid Fibroblast-like Synoviocytes.

Wada K, Ishibashi HK, Nakamura Y, Saruga T, Imaizumi T, Kurose A, Tachizaki M, Kawaguchi S, Seya K, Oishi K, Sasaki E, Wada K, Ishibashi Y

In vivo (Athens, Greece) 39 ( 6 ) 3236 - 3246 2025年11月

Heat-killed Lactococcus lactis subsp. lactis L8 ameliorates dextran sulfate sodium-induced colitis in mice

Kawaguchi Shogo, Chinda Daisuke, Ota Shinji, Tonouchi Akio, Maeda Hayato, Miura Kazuhide, Soma Go, Hiraga Hiroto, Ueno Kayo, Niioka Takenori, Tachizaki Mayuki, Seya Kazuhiko, Imaizumi Tadaatsu, Fukuda Shinsaku, Sakuraba Hirotake

Journal of Clinical Biochemistry and Nutrition advpub ( 0 ) 2025年02月

胃内視鏡検診における画像強調内視鏡検査と病変検出AIシステム導入の有効性評価

珍田大輔, 川口章吾, 安田耕平, 藤原沙映, 尾崎未紗, 佐々木聡, 下山克

日本消化器がん検診学会雑誌 63 ( 5 ) 652 - 660 2025年

Role of CD34 in calcification of human aortic valve interstitial cells from patients with aortic valve stenosis.

Men S, Yu Z, Liu X, Daitoku K, Tachizaki M, Kawaguchi S, Imaizumi T, Minakawa M, Seya K

Journal of pharmacological sciences 156 ( 3 ) 198 - 207 2024年11月

増大号炎症性腸疾患2024 主題炎症性腸疾患の長期経過潰瘍性大腸炎の長期予後

蓮井桂介, 平賀寛人, 太田真二, 浅利享, 澤田洋平, 立田哲也, 川口章吾, 菊池英純, 珍田大輔, 明本由衣, 坂本義之, 袴田健一, 福田眞作, 櫻庭裕丈

胃と腸 59 ( 10 ) 1521 - 1530 2024年10月

Cylindromatosis lysine 63 deubiquitinase (CYLD) suppress TLR3-mediated CCL5 expression in human renal proximal tubular epithelial cells.

Tachizaki M, Kobori Y, Kawaguchi S, Seya K, Tanaka H, Imaizumi T

Molecular biology reports 51 ( 1 ) 974 2024年09月

Expression of ISG60 is induced by TLR3 signaling in BEAS‑2B bronchial epithelial cells: Possible involvement in CXCL10 expression.

Tanaka Y, Imaizumi T, Kobori Y, Tachizaki M, Shiratori T, Dobashi M, Sato M, Kawaguchi S, Seya K, Tasaka S

Molecular medicine reports 30 ( 3 ) 2024年09月

Toll-Like Receptor 7-Expressed Macrophages Are Involved in the Pathogenesis of Esophageal Achalasia and Esophagogastric Junction Outflow Obstruction.

Kaizuka M, Tatsuta T, Kawaguchi S, Yoshizawa T, Yoshida S, Tateda T, Sawada Y, Ota S, Hayamizu S, Hasui K, Kikuchi H, Hiraga H, Chinda D, Muroya T, Hakamada K, Kijima H, Mikami T, Fukuda S, Sakuraba H

Digestion 1 - 12 2024年08月

Interferon-stimulated gene 56 positively regulates Toll-like receptor 3-mediated CXCL10 expression in human renal proximal tubular epithelial cells.

Tachizaki M, Sakamoto S, Kobori Y, Asano Y, Kawaguchi S, Seya K, Tanaka H, Morita E, Imaizumi T

FEBS open bio 14 ( 8 ) 1303 - 1319 2024年06月

Resiquimod Induces C-C Motif Chemokine Ligand 2 Via Nuclear Factor-Kappa B in SH-SY5Y Human Neuroblastoma Cells.

Kaizuka M, Kawaguchi S, Tatsuta T, Tachizaki M, Kobori Y, Tanaka Y, Seya K, Matsumiya T, Imaizumi T, Sakuraba H

Neuromolecular medicine 26 ( 1 ) 16 - 16 2024年04月

Diamidobenzimidazole, an agonist of STING, induces the expression of retinoic acid-inducible gene-I and interferon-induced transmembrane protein 1 in BEAS-2B cells

Sato Mami, Imaizumi Tadaatsu, Ding Jiangli, Seya Kazuhiko, Kawaguchi Shogo, Tanaka Yusuke, Matsuzaki Yasushi, Matsumiya Tomoh, Matsubara Atsushi

Hirosaki Medical Journal 74 ( 1-4 ) 117 - 127 2024年03月

TMEM2 suppresses TLR3-mediated IFN-β/ISG56/CXCL10 expression in BEAS-2B bronchial epithelial cells.

Kobori Y, Tachizaki M, Imaizumi T, Tanaka Y, Seya K, Miki Y, Kawaguchi S, Matsumiya T, Tobisawa Y, Ohyama C, Tasaka S

Molecular biology reports 51 ( 1 ) 417 - 417 2024年03月

The inhibitory effect of DIF-3 on polyinosinic-polycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells.

Araya R, Men S, Uekusa Y, Yu Z, Kikuchi H, Daitoku K, Minakawa M, Kawaguchi S, Furukawa KI, Oshima Y, Imaizumi T, Seya K

Journal of pharmacological sciences 154 ( 3 ) 157 - 165 2024年03月

Possible involvement of DExD/H box helicase 60 in synovial inflammation of rheumatoid arthritis: role of toll-like receptor 3 signaling.

Nakamura Y, Ishibashi HK, Saruga T, Imaizumi T, Kurose A, Tachizaki M, Kawaguchi S, Seya K, Sasaki E, Ishibashi Y

Molecular biology reports 51 ( 1 ) 131 - 131 2024年01月

TLR3 signaling-induced interferon-stimulated gene 56 plays a role in the pathogenesis of rheumatoid arthritis.

Ishibashi HK, Nakamura Y, Saruga T, Imaizumi T, Kurose A, Kawaguchi S, Seya K, Sasaki E, Ishibashi Y

Experimental biology and medicine (Maywood, N.J.) 249 10122 2024年

Expression of interferon-stimulated gene 20 (ISG20), an antiviral effector protein, in glomerular endothelial cells: possible involvement of ISG20 in lupus nephritis.

Karasawa T, Sato R, Imaizumi T, Fujita M, Aizawa T, Tsugawa K, Mattinzoli D, Kawaguchi S, Seya K, Terui K, Joh K, Tanaka H

Renal failure 45 ( 1 ) 2224890 - 2224890 2023年12月

Polygonum tinctorium leaf extract ameliorates high-fat diet-induced intestinal epithelial damage in mice.

Kawaguchi S, Sakuraba H, Kikuchi H, Matsuki K, Hayashi Y, Ding J, Tanaka Y, Seya K, Matsumiya T, Hiraga H, Fukuda S, Sasaki K, Imaizumi T

Experimental and therapeutic medicine 25 ( 3 ) 112 - 112 2023年03月

The double-stranded RNA-dependent protein kinase PKR negatively regulates the protein expression of IFN-β induced by RIG-I signaling.

Matsumiya T, Shiba Y, Ding J, Kawaguchi S, Seya K, Imaizumi T

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 37 ( 2 ) e22780 2023年02月

ER export signals mediate plasma membrane localization of transmembrane protein TMEM72.

Ding J, Matsumiya T, Miki Y, Hayakari R, Shiba Y, Kawaguchi S, Seya K, Imaizumi T

The FEBS journal 290 ( 10 ) 2636 - 2657 2022年12月

Glomerular endothelial expression of type I IFN-stimulated gene, DExD/H-Box helicase 60 via toll-like receptor 3 signaling: possible involvement in the pathogenesis of lupus nephritis.

Karasawa T, Sato R, Imaizumi T, Hashimoto S, Fujita M, Aizawa T, Tsugawa K, Kawaguchi S, Seya K, Terui K, Tanaka H

Renal failure 44 ( 1 ) 137 - 145 2022年12月

Toll-like receptor 3 signaling induces interferon-induced transmembrane protein 1 in BEAS-2B cells.

Dobashi M, Shiratori T, Imaizumi T, Hashimoto S, Kawaguchi S, Seya K, Tasaka S

Experimental biology and medicine (Maywood, N.J.) 247 ( 21 ) 1917 - 1922 2022年11月

Polygonum tinctorium leaves suppress sodium dextran sulfate-induced colitis through interleukin-10-related pathway.

Asari T, Kikuchi H, Kawaguchi S, Sakuraba H, Yoshida S, Akemoto Y, Maeda T, Shinji O, Murai Y, Higuchi N, Hoshi K, Fukutoku Y, Hiraga H, Sasaki K, Fukuda S

Biochemistry and biophysics reports 30 101272 - 101272 2022年07月

Tacrolimus Up-regulates Expression of TGFβ Receptor Type II via ERK, Providing Protection Against Intestinal Epithelial Injury.

Satake M, Sakuraba H, Hiraga H, Yoshida S, Akemoto Y, Ota S, Murai Y, Hasui K, Kawaguchi S, Kikuchi H, Fukuda S

In vivo (Athens, Greece) 36 ( 4 ) 1684 - 1693 2022年07月

Elucidation of the inhibitory effect of (+)-hopeaphenol on polyinosinic-polycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells.

Xu L, Yu Z, Uekusa Y, Kawaguchi S, Kikuchi H, Daitoku K, Minakawa M, Motomura S, Furukawa KI, Oshima Y, Seya K, Imaizumi T

Journal of pharmacological sciences 149 ( 3 ) 147 - 157 2022年07月

胃原発胎児消化管上皮類似癌に対して内視鏡的粘膜下層剥離術を施行し、術後経過を観察しえた1例

佐藤諭, 珍田大輔, 福徳友香理, 新井徹, 澤田洋平, 立田哲也, 川口章吾, 菊池英純, 櫻庭裕丈, 三上達也, 吉澤忠司, 鬼島宏, 福田眞作

日本消化器内視鏡学会誌 168回 100 - 100 2022年07月

Tryptanthrin attenuates TLR3-mediated STAT1 activation in THP-1 cells.

Numao N, Kawaguchi S, Ding J, Karasawa T, Seya K, Matsumiya T, Kikuchi H, Sakuraba H, Fukuda S, Imaizumi T

Immunologic research 70 ( 5 ) 688 - 697 2022年06月

TMEM72の細胞内局在に関する検討

丁江麗, 松宮朋穂, 川口章吾, 瀬谷和彦, 今泉忠淳

弘前医学 72 ( 1-4 ) 102 - 102 2022年03月

Long-term efficacy and tolerability of dose-adjusted thiopurine treatment in maintaining remission in inflammatory bowel disease patients with NUDT15 heterozygosity.

Maeda T, Sakuraba H, Hiraga H, Yoshida S, Kakuta Y, Kikuchi H, Kawaguchi S, Hasui K, Tatsuta T, Chinda D, Mikami T, Fukuda S

Intestinal research 20 ( 1 ) 90 - 100 2022年01月

Effect of sera from lupus patients on the glomerular endothelial fibrinolysis system.

Sato R, Aizawa T, Imaizumi T, Tsugawa K, Kawaguchi S, Seya K, Terui K, Tanaka H

Pediatrics international : official journal of the Japan Pediatric Society 64 ( 1 ) e15099 2022年01月

Evaluation of metabolic dysfunction-associated fatty liver disease using FibroScan, diet, and microbiota: A large cross-sectional study.

Tateda T, Iino C, Sasada T, Sato S, Igarashi G, Kawaguchi S, Mikami K, Endo T, Sawada K, Mikami T, Fukuda S, Nakaji S, Sakuraba H

PloS one 17 ( 11 ) e0277930 2022年

Expression of Zinc-Finger antiviral protein in hCMEC/D3 human cerebral microvascular cells: Effect of a toll-like receptor 3 agonist

Okudera M, Odawara M, Arakawa M, Kawaguchi S, Seya K, Matsumiya T, Sato R, Ding J, Morita E, Imaizumi T

Neuroimmunomodulation 29 ( 4 ) 1 - 10 2021年12月

Inhibitory effect of anti-malarial agents on the expression of proinflammatory chemokines via Toll-like receptor 3 signaling in human glomerular endothelial cells.

Sato R, Imaizumi T, Aizawa T, Watanabe S, Tsugawa K, Kawaguchi S, Seya K, Matsumiya T, Tanaka H

Renal failure 43 ( 1 ) 643 - 650 2021年12月

特集炎症性腸疾患の分子標的治療を総括する Ⅳ.接着分子阻害薬─ ベドリズマブの特性を生かしたIBD 治療

櫻庭裕丈, 平賀寛人, 蓮井桂介, 菊池英純, 村井康久, 川口章吾, 樋口直樹, 明本由衣, 福田眞作

INTESTINE 25 ( 3 ) 267 - 274 2021年09月

Hepatic macrophages express melanoma differentiation-associated gene 5 in nonalcoholic steatohepatitis

Kawaguchi S, Sakuraba H, Horiuchi M, Ding J, Matsumiya T, Seya K, Iino C, Endo T, Kikuchi H, Yoshida S, Hiraga H, Fukuda S, Imaizumi T

Inflammation 45 ( 1 ) 343 - 355 2021年09月

Expression of IFN-induced transmembrane protein 1 in glomerular endothelial cells.

Hashimoto S, Imaizumi T, Watanabe S, Aizawa T, Tsugawa K, Kawaguchi S, Seya K, Matsumiya T, Tanaka H

Pediatrics international : official journal of the Japan Pediatric Society 63 ( 9 ) 1075 - 1081 2021年09月

Daily Brazilian green propolis intake elevates blood artepillin C levels in humans.

Ding J, Matsumiya T, Hayakari R, Shiba Y, Kawaguchi S, Seya K, Ueno K, Imaizumi T

Journal of the science of food and agriculture 101 ( 11 ) 4855 - 4861 2021年08月

Porphyromonas gingivalis lipopolysaccharide induces interleukin-6 and c-c motif chemokine ligand 2 expression in cultured hCMEC/D3 human brain microvascular endothelial cells.

Sato N, Matsumoto T, Kawaguchi S, Seya K, Matsumiya T, Ding J, Aizawa T, Imaizumi T

Gerodontology 39 ( 2 ) 139 - 147 2021年02月

Tryptanthrin suppresses double-stranded RNA-induced CXCL10 expression via inhibiting the phosphorylation of STAT1 in human umbilical vein endothelial cells

Shogo Kawaguchi, Hirotake Sakuraba, Hidezumi Kikuchi, et al.

Molecular Immunology 2021年01月

Role of MDA5 in regulating CXCL10 expression induced by TLR3 signaling in human rheumatoid fibroblast-like synoviocytes.

Saruga T, Imaizumi T, Kawaguchi S, Seya K, Matsumiya T, Sasaki E, Sasaki N, Uesato R, Ishibashi Y

Molecular biology reports 48 ( 1 ) 425 - 433 2021年01月

Interleukin-6 via Toll-Like Receptor 3 Signaling Attenuates the Expression of Proinflammatory Chemokines in Human Podocytes.

Umetsu H, Watanabe S, Imaizumi T, Aizawa T, Tsugawa K, Kawaguchi S, Seya K, Matsumiya T, Tanaka H

Kidney & blood pressure research 46 ( 2 ) 207 - 218 2021年

IFIT Proteins Are Involved in CXCL10 Expression in Human Glomerular Endothelial Cells Treated with a Toll-Like Receptor 3 Agonist.

Imaizumi T, Hashimoto S, Sato R, Umetsu H, Aizawa T, Watanabe S, Kawaguchi S, Matsumiya T, Seya K, Ding J, Tanaka H

Kidney & blood pressure research 46 ( 1 ) 74 - 83 2021年

ISG56 is involved in CXCL10 expression induced by TLR3 signaling in BEAS-2B bronchial epithelial cells.

Shiratori T, Imaizumi T, Hirono K, Kawaguchi S, Matsumiya T, Seya K, Tasaka S

Experimental lung research 46 ( 6 ) 195 - 202 2020年05月

Polyinosinic-Polycytidylic Acid Induces CXCL1 Expression in Cultured hCMEC/D3 Human Cerebral Microvascular Endothelial Cells.

Li Y, Imaizumi T, Matsumiya T, Seya K, Kawaguchi S, Ding J, Ohkuma H

Neuroimmunomodulation 27 ( 1 ) 38 - 47 2020年

Interferon-induced transmembrane protein 1 and Myxovirus resistance protein 1 are induced by polyinosinic-polycytidylic acid in cultured hCMEC/D3 human cerebral microvascular endothelial cells.

Tadaatsu Imaizumi, Urara Satake, Ruri Miyashita, Shogo Kawaguchi, Tomoh Matsumiya, Kazuhiko Seya, Jiangli Ding, Hiroshi Tanaka

Journal of neuroimmunology 337 577047 - 577047 2019年12月

Melanoma Differentiation-Associated Gene 5 Positively Modulates TNF-α-Induced CXCL10 Expression in Cultured HuH-7 and HLE Cells.

Shogo Kawaguchi, Hirotake Sakuraba, Toshihiro Haga, Tomoh Matsumiya, Kazuhiko Seya, Tetsu Endo, Naoya Sawada, Chikara Iino, Hidezumi Kikuchi, Hiroto Hiraga, Shinsaku Fukuda, Tadaatsu Imaizumi

Inflammation 42 ( 6 ) 2095 - 2104 2019年12月

Endothelial expression of fractalkine (CX3CL1) is induced by Toll-like receptor 3 signaling in cultured human glomerular endothelial cells.

Koji Hirono, Tadaatsu Imaizumi, Tomomi Aizawa, Shojiro Watanabe, Koji Tsugawa, Toshihiro Shiratori, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Etsuro Ito, Hiroshi Tanaka

Modern rheumatology 1 - 8 2019年11月

〈一般演題抄録〉一本鎖RNA ウイルスのゲノムRNA 分解機構解明へ向けた基礎検討

木村紗也佳, 松宮朋穂, 吉田秀見, 瀬谷和彦, 川口章吾, 今泉忠淳

弘前医学 69 ( 1-4 ) 207 2019年03月

〈一般演題抄録〉胆道閉鎖症におけるウイルス感染の関与に関する分子生物学的検討

木村俊郎, 今泉忠淳, 吉田秀見, 松宮朋穂, 瀬谷和彦, 川口章吾, 早狩亮, 島田拓, 吉田達哉, 小林完, 平林健, 袴田健一

弘前医学 69 ( 1-4 ) 201 2019年03月

Cytosolic Sensors of Viral RNA Are Involved in the Production of Interleukin-6 via Toll-Like Receptor 3 Signaling in Human Glomerular Endothelial Cells.

Qiang Liu, Tadaatsu Imaizumi, Tomomi Aizawa, Koji Hirono, Shogo Kawaguchi, Shojiro Watanabe, Koji Tsugawa, Tomoh Matsumiya, Kazuhiko Seya, Hidemi Yoshida, Hiroshi Tanaka

Kidney & blood pressure research 44 ( 1 ) 62 - 71 2019年

Retinoic Acid-Inducible Gene-i and CXCL10 are Involved in Biliary Atresia

Kimura Toshiro, Imaizumi Tadaatsu, Yoshida Tatsuya, Shimada Taku, Hayakari Ryo, Kawaguchi Shogo, Yoshida Hidemi, Kobayashi Tamotsu, Hirabayashi Takeshi, Mizukami Hiroki, Kijima Hiroshi, Hakamada Kenichi

弘前医学 69 ( 1 ) 86 - 94 2019年

Gastric Focal Neutrophil Infiltration and Wide Duodenal Gastric Foveolar Metaplasia Are Histologic Discriminative Markers for Crohn's Disease and Behçet's Disease.

Akemoto Y, Sakuraba H, Tanaka M, Hiraga H, Kikuchi H, Morohashi S, Ota S, Hasui K, Satake M, Watanabe R, Tanaka N, Kawaguchi S, Tatsuta T, Sawaya M, Chinda D, Mikami T, Ishiguro Y, Kijima H, Fukuda S

Digestion 100 ( 3 ) 210 - 219 2019年

Effect of low-concentration amyloid-β 1–42 (Aβ42) on human neuroblastoma SH-SY5Y cell viability: neuroprotective potential of combination use with carnosic acid, rebamipide, edaravone, and resveratrol

Yoshida Hidemi, Hashimoto Yuko, Fukushima Takashi, Tanji Kunikazu, Matsumiya Tomoh, Seya Kazuhiko, Kawaguchi Shogo, Imaizumi Tadaatsu

弘前医学 70 ( 1 ) 24 - 38 2019年

Induction of C-C motif chemokine ligand 2 through Toll-like receptor 3 signaling in human cerebral microvascular endothelial cell/D3 cells: possible regulation by nuclear factor-κB

Naoko Sassa, Koji Hirono, Toshihiro Shiratori, Shogo Kawaguchi, Tomoh Matsumiya, Hidemi Yoshida, Kazuhiko Seya, Hiroshi Tanaka, Tadaatsu Imaizumi

Clinical and Experimental Neuroimmunology 10 ( 3 ) 197 - 203 2019年

Effect of low-concentration amyloid-p 1-42 (Ap42) on human neuroblastoma SH-SY5Y cell viability: Neuroprotective potential of combination use with carnosic acid, rebamipide, edaravone, and resveratrol

Hidemi Yoshida, Yuko Hashimoto, Takashi Fukushima, Kunikazu Tanji, Tomoh Matsumiya, Kazuhiko Seya, Shogo Kawaguchi, Tadaatsu Imaizumi

Hirosaki Medical Journal 70 ( 1 ) 24 - 38 2019年

Interferon-stimulated gene 60 (ISG60) constitutes a negative feedback loop in the downstream of TLR3 signaling in hCMEC/D3 cells

Imaizumi T, Sassa N, Kawaguchi S, et al.

Journal of Neuroimmunology 2018年09月

The Essential Role of Double-Stranded RNA-Dependent Antiviral Signaling in the Degradation of Nonself Single-Stranded RNA in Nonimmune Cells.

Kimura S, Matsumiya T, Shiba Y, Nakanishi M, Hayakari R, Kawaguchi S, Yoshida H, Imaizumi T

Journal of immunology (Baltimore, Md. : 1950) 201 ( 3 ) 1044 - 1052 2018年08月

Gnetin C suppress double-stranded RNA-induced C-C motif chemokine ligand 2 (CCL2) and CCL5 production by inhibiting Toll-like receptor 3 signaling pathway

Yoshida H, Imaizumi T, Matsumiya T, et al.

Biomedical Research 2018年07月

The essential role of double-stranded RNA-dependent antiviral signaling in the degeneration of nonself single-stranded RNA in nonimmune cells

Kimura S, Matsumiya T, Shiba Y, et al.

Journal of Immunology 2018年06月

Toll-like receptor 3 signaling contributes to regional neutrophil recruitment in cultured human glomerular endothelial cells

Liu Q, Imaizumi T, Kawaguchi S, et al.

Nephron 2018年05月

Gnetin C, a resveratol dimer, reduces amyloid-beta 1-42 production and ameliorates Abeta42-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells

Seino S, Kimoto T, Yoshida H, et al.

Biomedical Research 2018年03月

Vimentin-positive gastric adenocarcinoma arising in a hyperplastic polyp

Shogo Kawaguchi, Tetsuro Yoshimura, Hirotake Sakuraba, et al.

Clinical Journal of Gastroenterology 2018年02月

治療抵抗性水疱性類天疱瘡患者の早期胃癌ESD後にステロイド減量が可能となった１例

荒木康光, 吉村徹郎, 浅利享, 菊池公二, 川口章吾, 和田豊人, 楠美智巳, 福田眞作

日本消化器内視鏡学会雑誌 60 ( 1 ) 21 - 26 2018年

Estimation of perioperative invasiveness of colorectal endoscopic submucosal dissection evaluated by energy metabolism

Chinda Daisuke, Kawaguchi Shogo, Kikuchi Hidezumi, Hiraga Hiroto, Sawaya Manabu, Sakuraba Hirotake, Mikami Tatsuya, Fukuda Shinsaku, Shimoyama Tadashi, Miyazawa Kuniaki, Arai Tetsu, Hayamizu Shiro, Yanagimachi Miyuki, Tsukamoto Toshiaki, Akitaya Kazuki, Tatsuta Tetsuya

Ｊｏｕｒｎａｌ　ｏｆ　Ｃｌｉｎｉｃａｌ　Ｂｉｏｃｈｅｍｉｓｔｒｙ　ａｎｄ　Ｎｕｔｒｉｔｉｏｎ 63 ( 2 ) 164 - 167 2018年

Gnetin C, a resveratrol dimer, reduces amyloid-β 1–42 (Aβ42) production and ameliorates Aβ42-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells

SEINO Syota, TANAKA Hiroshi, IMAIZUMI Tadaatsu, KIMOTO Takeru, YOSHIDA Hidemi, TANJI Kunikazu, MATSUMIYA Tomoh, HAYAKARI Ryo, SEYA Kazuhiko, KAWAGUCHI Shogo, TSURUGA Kazushi

Biomedical Research 39 ( 3 ) 105 - 115 2018年

Gnetin C suppresses double-stranded RNA-induced C-C motif chemokine ligand 2 (CCL2) and CCL5 production by inhibiting Toll-like receptor 3 signaling pathway

YOSHIDA Hidemi, IMAIZUMI Tadaatsu, MATSUMIYA Tomoh, SEYA Kazuhiko, KAWAGUCHI Shogo, TANAKA Hiroshi

Biomedical Research 39 ( 5 ) 231 - 240 2018年

Expression of CCL5 is induced by polyinosinic : polycytidylic acid in cultured hCMEC/D3 human brain microvascular endothelial cells

Akine Arai, Hidemi Yoshida, Ryo Hayakari, Tomoh Matsumiya, Shogo Kawaguchi, Kazuhiko Seya, Hiroshi Tanaka, Tadaatsu Imaizumi

Clinical and Experimental Neuroimmunology 8 ( 4 ) 331 - 340 2017年11月

Chloroquine attenuates TLR3/IFN-β signaling in cultured normal human mesangial cells: A possible protective effect against renal damage in lupus nephritis.

Imaizumi T, Hayakari R, Matsumiya T, Yoshida H, Tsuruga K, Watanabe S, Kawaguchi S, Tanaka H

Modern rheumatology 27 ( 6 ) 1004 - 1009 2017年11月

Cylindromatosis (CYLD), a Deubiquitinase, Attenuates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells.

Imaizumi T, Hayakari R, Watanabe S, Aizawa T, Matsumiya T, Yoshida H, Tsuruga K, Kawaguchi S, Tanaka H

Kidney & blood pressure research 42 ( 5 ) 942 - 950 2017年

甲状腺原発悪性リンパ腫治療後に発症したEBウイルス陽性消化管リンパ腫の1例

渡邊里奈, 福田眞作, 川口章吾, 吉村徹郎, 浅利享, 澤田洋平, 荒木康光, 菊池公二, 和田豊人, 楠美智巳

日本消化器内視鏡学会雑誌 59 ( 2 ) 171 - 176 2017年

Interferon-stimulated gene (ISG) 60, as well as ISG56 and ISG54, positively regulates TLR3/IFN-β/STAT1 axis in U373MG human astrocytoma cells.

Imaizumi T, Yoshida H, Hayakari R, Xing F, Wang L, Matsumiya T, Tanji K, Kawaguchi S, Murakami M, Tanaka H

Neuroscience research 105 35 - 41 2016年04月

Interferon-Stimulated Gene 15, a Type I Interferon-Dependent Transcript, Is Involved in a Negative Feedback Loop in Innate Immune Reactions in Human Mesangial Cells.

Imaizumi T, Shimada T, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Kawaguchi S, Murakami M, Joh K, Tanaka H

Nephron 132 ( 2 ) 144 - 52 2016年

Interferon (IFN)-Induced Protein 35 (IFI35), a Type I Interferon-Dependent Transcript, Upregulates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells.

Imaizumi T, Yano C, Numata A, Tsugawa K, Hayakari R, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Kawaguchi S, Murakami M, Tanaka H

Kidney & blood pressure research 41 ( 5 ) 635 - 642 2016年

Desferrioxamine, An Iron Chelator, Induces CXCL8 Expression in U373MG Human Astrocytoma Cells

Onda Kaoru, Yoshida Hidemi, Hayakari Ryo, Xing Fei, Wang Lian, Matsumiya Tomoh, Kawaguchi Shogo, Murakami Manabu, Imaizumi Tadaatsu

弘前医学 66 ( 2 ) 127 - 134 2016年

Alteration of Antiviral Signalling by Single Nucleotide Polymorphisms (SNPs) of Mitochondrial Antiviral Signalling Protein (MAVS).

Xing F, Matsumiya T, Hayakari R, Yoshida H, Kawaguchi S, Takahashi I, Nakaji S, Imaizumi T

PloS one 11 ( 3 ) e0151173 2016年

Toll-like receptor 3 signaling contributes to the expression of a neutrophil chemoattractant, CXCL1 in human mesangial cells.

Imaizumi T, Aizawa T, Segawa C, Shimada M, Tsuruga K, Kawaguchi S, Matsumiya T, Yoshida H, Joh K, Tanaka H

Clinical and experimental nephrology 19 ( 5 ) 761 - 70 2015年10月

Carnosic acid attenuates apoptosis induced by amyloid-β 1-42 or 1-43 in SH-SY5Y human neuroblastoma cells.

Meng P, Yoshida H, Tanji K, Matsumiya T, Xing F, Hayakari R, Wang L, Tsuruga K, Tanaka H, Mimura J, Kosaka K, Itoh K, Takahashi I, Kawaguchi S, Imaizumi T

Neuroscience research 94 1 - 9 2015年05月

Desferrioxamine, an iron chelator, inhibits CXCL10 expression induced by polyinosinic-polycytidylic acid in U373MG human astrocytoma cells.

Imaizumi T, Sakashita N, Mushiga Y, Yoshida H, Hayakari R, Xing F, Wang L, Matsumiya T, Tanji K, Chiba Y, Furudate K, Kawaguchi S, Murakami M, Tanaka H

Neuroscience research 94 10 - 6 2015年05月

下血を契機に発見された小腸濾胞性リンパ腫の1例

川口章吾, 吉村徹郎, 千葉裕樹, 和田豊人, 速水史郎, 池永照史郎一期, 楠美智巳, 福田眞作

日本消化器内視鏡学会雑誌 56 ( 6 ) 1974 - 1979 2014年

von Recklinghausen 病に合併した Vater 乳頭部ソマトスタチノーマの1例

川口章吾, 山形亮, 高橋誠司, 齋藤太郎, 村田有志, 八木橋操六, 福田眞作

日本消化器内視鏡学会雑誌 = Gastroenterological endoscopy 53 ( 5 ) 1435 - 1440 2011年05月

Interferon-alpha2b induces p21cip1/waf1 degradation and cell proliferation in HeLa cells.

Ota K, Matsumiya T, Sakuraba H, Imaizumi T, Yoshida H, Kawaguchi S, Fukuda S, Satoh K

Cell cycle (Georgetown, Tex.) 9 ( 1 ) 131 - 9 2010年01月

Cyclosporine regulates intestinal epithelial apoptosis via TGF-beta-related signaling.

Satoh Y, Ishiguro Y, Sakuraba H, Kawaguchi S, Hiraga H, Fukuda S, Nakane A

American journal of physiology. Gastrointestinal and liver physiology 297 ( 3 ) G514 - 9 2009年09月

Retinoic acid-inducible gene-I is constitutively expressed and involved in IFN-gamma-stimulated CXCL9-11 production in intestinal epithelial cells.

Kawaguchi S, Ishiguro Y, Imaizumi T, Mori F, Matsumiya T, Yoshida H, Ota K, Sakuraba H, Yamagata K, Sato Y, Tanji K, Haga T, Wakabayashi K, Fukuda S, Satoh K

Immunology letters 123 ( 1 ) 9 - 13 2009年03月

治療抵抗性潰瘍性大腸炎におけるTransforming growth factor-β受容体の発現抑制

島谷孝司, 石黒陽, 川口章吾, 佐藤裕紀, 平賀寛人, 山口佐都子, 櫻庭裕丈, 藤田均, 山形和史, 福田眞作

弘前医学 59 ( 2 ) 90 - 97 2008年

[A case of pneumatosis cystoides intestinalis and intestinal pseudo-obstruction in overlap syndrome manifested by polymyositis and scleroderma].

Sawamura N, Ishiguro Y, Yamagata K, Kawaguchi S, Yoshimura T, Mikami T, Sasaki Y, Fukuda S, Munakata A

Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 102 ( 6 ) 706 - 11 2005年06月

偽性腸閉塞症および腸管嚢腫様気腫を合併した多発性筋炎と強皮症によるoverlap症候群の1例

澤村典子, 石黒陽, 山形和史, 川口章吾, 吉村徹郎, 三上達也, 佐々木賀広, 福田眞作, 棟方昭博

日本消化器病学会雑誌 102 ( 6 ) 706 - 711 2005年

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