論文 - 下山 修司
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Co-Expression of Tardive Dyskinesia and Drug-Induced Parkinsonism in Rats Chronically Treated With Haloperidol
Kinoshita, I; Nishijima, H; Nakamura, T; Kon, T; Shimoyama, S; Hikichi, H; Suzuki, C; Tomiyama, M
NEUROPSYCHOPHARMACOLOGY REPORTS 45 ( 1 ) e12524 2025年03月
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Prepartum bumetanide treatment reverses altered neonatal social communication but nonspecifically reduces postpubertal social behavior in a mouse model of fragile X syndrome
Yui Sakamoto, Takeshi Takano, Shuji Shimoyama, Takeshi Hiramoto, Noboru Hiroi, Kazuhiko Nakamura
Genomic Psychiatry 1 - 12 2024年12月
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Intranasal administration of trehalose reduces α-synuclein oligomers and accelerates α-synuclein aggregation.
Makoto T Tanaka, Yasuo Miki, Fumiaki Mori, Tomoya Kon, Tomonori Furukawa, Shuji Shimoyama, Yota Tatara, Taku Ozaki, Conceição Bettencourt, Thomas T Warner, Koichi Wakabayashi
Brain communications 6 ( 4 ) fcae193 2024年08月
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Benzodiazepine-induced cell growth inhibition via GABAA receptor- and TSPO-independent pathways
Shuji Shimoyama, Tomonori Furukawa, Shinya Ueno
Hirosaki Medical Journal 74 52 - 60 2024年03月
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Sex-related differences in the effect of exercise on protein profiles of serum
Tomonori Furukawa, Shuji Shimoyama, Aogi Kobayashi, Yota Tatara, Yoshikazu Nikaido, Shinya Ueno
Hirosaki Medical Journal 74 40 - 51 2024年03月
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Attempt to Develop Therapeutic Drug for Autism by Targeting IGF-1: Exploration of Small Compounds for IGF-1 Gene Expression
Nakamura, K; Shimoyama, S; Sakamoto, Y; Furukawa, T; Hasegawa, A; Shimizu, R; Kojima, H; Ueno, S
NEUROPSYCHOPHARMACOLOGY 48 128 - 128 2023年12月
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Qualitative and quantitative alterations of synaptotagmin 13 in synucleinopathies
Miki, Y; Tanaka, M; Shimoyama, S; Nakahara, A; Kakita, A; Wakabayashi, K
BRAIN PATHOLOGY 33 2023年09月
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Intranasal administration of trehalose reduces α-synuclein oligomers by accelerating aggregate formation in a mouse model of multiple system atrophy
Tanaka, M; Miki, Y; Mori, F; Furukawa, T; Shimoyama, S; Tatara, Y; Wakabayashi, K
BRAIN PATHOLOGY 33 2023年09月
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Effect of Ionizing Radiation on the Intercellular Network of Murine Cerebral Cortical Neurons
Masaru Yamaguchi, Takakiyo Tsujiguchi, Tomonori Furukawa, Shuji Shimoyama, Toshiya Nakamura, Yasushi Mariya and Junko Yamada
Radiation Environment and Medicine 12 ( 1 ) 2023年02月
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Intraperitoneal Administration of Etizolam Improves Locomotor Function in Mice After Spinal Cord Injury
Kenya Saruta, Tatsuhiro Fukutoku, Gentaro Kumagai, Toshihide Nagaoki, Manami Tsukuda, Yohshiro Nitobe, Kanichiro Wada, Toru Asari, Taku Fujita, Isamu Sasaki, Yoshikazu Nikaido, Shuji Shimoyama, Shinya Ueno, Yasuyuki Ishibashi
Neurotrauma Reports 4 ( 1 ) 2023年02月
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TRPA1 as a O2 sensor detects microenvironmental hypoxia in the mice anterior cingulate cortex.
Ryo Kawabata, Shuji Shimoyama, Shinya Ueno, Ikuko Yao, Akiko Arata, Kohei Koga
Scientific reports 13 ( 1 ) 2960 - 2960 2023年02月
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Pathological substrate of memory impairment in multiple system atrophy.
Yasuo Miki, Kunikazu Tanji, Kana Shinnai, Makoto T Tanaka, Firat Altay, Sandrine C Foti, Catherine Strand, Takanori Sasaki, Tomoya Kon, Shuji Shimoyama, Tomonori Furukawa, Haruo Nishijima, Hiromi Yamazaki, Yasmine T Asi, Conceição Bettencourt, Zane Jaunmuktane, Mari Tada, Fumiaki Mori, Hiroki Mizukami, Masahiko Tomiyama, Hilal A Lashuel, Tammaryn Lashley, Akiyoshi Kakita, Helen Ling, Andrew J Lees, Janice L Holton, Thomas T Warner, Koichi Wakabayashi
Neuropathology and applied neurobiology 48 ( 7 ) e12844 2022年07月
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The role of neutrophil gelatinase-associated lipocalin and iron homeostasis in object recognition impairment in aged sepsis-survivor rats.
Nikaido Y, Midorikawa Y, Furukawa T, Shimoyama S, Takekawa D, Kitayama M, Ueno S, Kushikata T, Hirota K
Scientific reports 12 ( 1 ) 249 - 249 2022年01月
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Impaired Cognitive Function and Hippocampal Changes Following Chronic Diazepam Treatment in Middle-Aged Mice.
13 777404 - 777404 2021年11月
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Copy number variations in Japanese children with autism spectrum disorder.
Yui Sakamoto, Shuji Shimoyama, Tomonori Furukawa, Masaki Adachi, Michio Takahashi, Tamaki Mikami, Michito Kuribayashi, Ayako Osato, Daiki Tsushima, Manabu Saito, Shinya Ueno, Kazuhiko Nakamura
Psychiatric genetics 31 ( 3 ) 79 - 87 2021年02月
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Effects of voluntary and forced exercises on motor function recovery in intracerebral hemorrhage rats.
Chihiro Sato, Kunikazu Tanji, Shuji Shimoyama, Mitsuru Chiba, Misaki Mikami, Shuhei Koeda, Koshi Sumigawa, Kazuki Akahira, Junko Yamada
NeuroReport 31 ( 2 ) 189 - 196 2020年01月
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Lipopolysaccharide induces mouse translocator protein (18 kDa) expression via the AP-1 complex in the microglial cell line, BV-2.
Shimoyama S, Furukawa T, Ogata Y, Nikaido Y, Koga K, Sakamoto Y, Ueno S, Nakamura K
PloS one 14 ( 9 ) e0222861 - e0222861 2019年09月
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Phospholipase C-related inactive protein type-1 deficiency affects anesthetic electroencephalogram activity induced by propofol and etomidate in mice.
Tomonori Furukawa, Yoshikazu Nikaido, Shuji Shimoyama, Yoshiki Ogata, Tetsuya Kushikata, Kazuyoshi Hirota, Takashi Kanematsu, Masato Hirata, Shinya Ueno
Journal of Anesthesia 33 ( 4 ) 531 - 542 2019年08月
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Anti-hypersensitive effect of angiotensin (1-7) on streptozotocin-induced diabetic neuropathic pain in mice.
Yoshiki Ogata, Wataru Nemoto, Ryota Yamagata, Osamu Nakagawasai, Shuji Shimoyama, Tomonori Furukawa, Shinya Ueno, Koichi Tan-No
European journal of pain (London, England) 23 ( 4 ) 739 - 749 2019年04月
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遺伝子Tspoの発現制御メカニズムの解明
下山 修司, 古川 智範, 小潟 佳輝, 中村 和彦, 上野 伸哉
弘前医学 69 ( 1-4 ) 207 - 207 2019年03月
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Stimulating muscarinic M<sub>1</sub> receptors in the anterior cingulate cortex reduces mechanical hypersensitivity via GABAergic transmission in nerve injury rats.
Koga K, Matsuzaki Y, Migita K, Shimoyama S, Eto F, Nakagawa T, Matsumoto T, Terada K, Mishima K, Furue H, Honda K
Brain research 1704 187 - 195 2019年02月
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Alteration of autophagy-related proteins in peripheral blood mononuclear cells of patients with Parkinson's disease.
Yasuo Miki, Shuji Shimoyama, Tomoya Kon, Tatsuya Ueno, Ryo Hayakari, Kunikazu Tanji, Tomoh Matsumiya, Eiki Tsushima, Fumiaki Mori, Koichi Wakabayashi, Masahiko Tomiyama
Neurobiology of aging 63 33 - 43 2018年03月
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Chronic inflammatory pain induced GABAergic synaptic plasticity in the adult mouse anterior cingulate cortex
Kohei Koga, Shuji Shimoyama, Akihiro Yamada, Tomonori Furukawa, Yoshikazu Nikaido, Hidemasa Furue, Kazuhiko Nakamura, Shinya Ueno
Molecular Pain 14 174480691878347 2018年01月
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Propofol Anesthesia Is Reduced in Phospholipase C-Related Inactive Protein Type-1 Knockout Mice.
Nikaido Y, Furukawa T, Shimoyama S, Yamada J, Migita K, Koga K, Kushikata T, Hirota K, Kanematsu T, Hirata M, Ueno S
The Journal of pharmacology and experimental therapeutics 361 ( 3 ) 367 - 374 2017年06月
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Chronic diazepam administration increases the expression of Lcn2 in the CNS.
Furukawa T, Shimoyama S, Miki Y, Nikaido Y, Koga K, Nakamura K, Wakabayashi K, Ueno S
Pharmacology research & perspectives 5 ( 1 ) e00283 2017年02月
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HSP90 Regulation of P2X7 Receptor Function Requires an Intact Cytoplasmic C-Terminus.
Migita K, Ozaki T, Shimoyama S, Yamada J, Nikaido Y, Furukawa T, Shiba Y, Egan TM, Ueno S
90 ( 2 ) 116 - 126 2016年08月
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GABA<sub>A</sub> 受容体応答の制御機構
上野 伸哉, 古川 智範, 二階堂 義和, 下山 修司, 柴 祐子, 山田 順子
弘前医学 66 ( 2-4 ) 105 - 109 2016年
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Dephosphorylation of Sp1 at Ser-59 by Protein Phosphatase 2A (PP2A) is required for induction of CYP1A1 transcription after treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin or omeprazole
Shuji Shimoyama, Shuya Kasai, Brigitte Kahn-Perles, Hideaki Kikuchi
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS 1839 ( 2 ) 107 - 115 2014年03月
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The mycotoxin patulin decreases expression of density-enhanced phosphatase-1 by down-regulating PPARγ in human colon cancer cells.
Katsuyama A, Konno T, Shimoyama S, Kikuchi H
The Tohoku journal of experimental medicine 233 ( 4 ) 265 - 274 2014年
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Involvement of CREM in CYP1A1 induction through ligand-independent activation pathway of aryl hydrocarbon receptor in HepG2 cells
Eriko Sasamori, Shuji Shimoyama, Shinichi Fukushige, Hideaki Kikuchi
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 478 ( 1 ) 26 - 35 2008年10月