論文 - 西塚 誠
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Knockdown of RhoQ, a member of Rho GTPase, accelerates TGF-β-induced EMT in human lung adenocarcinoma.
Satoh K, Sakai S, Nishizuka M.
Biochem Biophys Rep. 32 101346 2022年09月
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Repression of RhoJ expression promotes TGF-β-mediated EMT in human non-small-cell lung cancer A549 cells.
Misa Nozaki, Makoto Nishizuka
Biochemical and biophysical research communications 566 94 - 100 2021年08月
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Knockdown of RhoE Expression Enhances TGF-β-Induced EMT (epithelial-to-mesenchymal transition) in Cervical Cancer HeLa Cells.
Makoto Nishizuka, Rina Komada, Masayoshi Imagawa
International journal of molecular sciences 20 ( 19 ) 2019年09月
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FAD104, a regulator of adipogenesis, is a novel suppressor of TGF-β-mediated EMT in cervical cancer cells.
Motoharu Goto, Shigehiro Osada, Masayoshi Imagawa, Makoto Nishizuka
Scientific reports 7 ( 1 ) 16365 - 16365 2017年11月
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Luteolin enhances oxidative stress tolerance via the daf-16 pathway in the nematode Caenorhabditis elegans
Yamamoto R., Takahashi E., Harada M., Sawahata I., Nishizuka M.
Food Science and Technology Research 2024年03月
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脂肪細胞分化制御因子fad104によるメラニン生成抑制機構の解明
西塚 誠
小柳財団報告書 2022年04月
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KCNMA1, a pore-forming α-subunit of BK channels, regulates insulin signalling in mature adipocytes.
Makoto Nishizuka, Wataru Horinouchi, Eri Yamada, Natsuki Ochiai, Shigehiro Osada, Masayoshi Imagawa
FEBS letters 590 ( 23 ) 4372 - 4380 2016年12月
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Fad24, a Positive Regulator of Adipogenesis, Is Required for S Phase Re-entry of C2C12 Myoblasts Arrested in G0 Phase and Involved in p27(Kip1) Expression at the Protein Level.
Natsuki Ochiai, Makoto Nishizuka, Shigehiro Osada, Masayoshi Imagawa
Biological & pharmaceutical bulletin 39 ( 5 ) 807 - 814 2016年05月
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FAD104, a Regulator of Adipogenesis and Osteogenesis, Interacts with the C-Terminal Region of STAT3 and Represses Malignant Transformation of Melanoma Cells.
Daiki Katoh, Makoto Nishizuka, Shigehiro Osada, Masayoshi Imagawa
Biological & pharmaceutical bulletin 39 ( 5 ) 849 - 855 2016年05月
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Fad104, a positive regulator of adipocyte differentiation, suppresses invasion and metastasis of melanoma cells by inhibition of STAT3 activity.
Daiki Katoh, Makoto Nishizuka, Shigehiro Osada, Masayoshi Imagawa
PloS one 10 ( 2 ) e0117197 - e0117197 2015年
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KCNK10, a tandem pore domain potassium channel, is a regulator of mitotic clonal expansion during the early stage of adipocyte differentiation.
Makoto Nishizuka, Takahiro Hayashi, Mami Asano, Shigehiro Osada, Masayoshi Imagawa
International journal of molecular sciences 15 ( 12 ) 22743 - 22756 2014年12月
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FAD104, a regulatory factor of adipogenesis, acts as a novel regulator of calvarial bone formation.
Keishi Kishimoto, Makoto Nishizuka, Daiki Katoh, Ayumi Kato, Shigehiro Osada, Masayoshi Imagawa
The Journal of biological chemistry 288 ( 44 ) 31772 - 31783 2013年11月
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Targeted disruption of fad24, a regulator of adipogenesis, causes pre-implantation embryonic lethality due to the growth defect at the blastocyst stage.
Natsuki Ochiai, Makoto Nishizuka, Tomomi Miyamoto, Ichiro Miyoshi, Masahito Ikawa, Shigehiro Osada, Masayoshi Imagawa
Biochemical and biophysical research communications 438 ( 2 ) 301 - 305 2013年08月
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Interactions of thyroid hormone receptor with Ku proteins and interleukin enhancer binding factor 3 modulate the promoter activity of thyroid-stimulating hormone alpha.
Masae Ohno, Mayu Fujita, Makoto Nishizuka, Shigehiro Osada, Masayoshi Imagawa
Biological & pharmaceutical bulletin 35 ( 3 ) 380 - 384 2012年
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Indispensable role of factor for adipocyte differentiation 104 (fad104) in lung maturation.
Keishi Kishimoto, Makoto Nishizuka, Takashi Ueda, Kenji Kajita, Shinya Ugawa, Shoichi Shimada, Shigehiro Osada, Masayoshi Imagawa
Experimental cell research 317 ( 15 ) 2110 - 2123 2011年09月
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Interleukin enhancer-binding factor 3 functions as a liver receptor homologue-1 co-activator in synergy with the nuclear receptor co-activators PRMT1 and PGC-1α.
Masae Ohno, Jun Komakine, Eiko Suzuki, Makoto Nishizuka, Shigehiro Osada, Masayoshi Imagawa
The Biochemical journal 437 ( 3 ) 531 - 540 2011年08月
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Factor for adipocyte differentiation 158 gene disruption prevents the body weight gain and insulin resistance induced by a high-fat diet.
Takahiro Hayashi, Yuriko Nozaki, Makoto Nishizuka, Masahito Ikawa, Shigehiro Osada, Masayoshi Imagawa
Biological & pharmaceutical bulletin 34 ( 8 ) 1257 - 1263 2011年
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RNA interference-mediated knockdown of the mouse gene encoding potassium channel subfamily K member 10 inhibits hormone-induced differentiation of 3T3-L1 preadipocytes.
Shuji Sato, Makoto Nishizuka, Mami Asano, Tsuyoshi Ohtake, Masayoshi Imagawa, Eiji Kobayashi
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 157 ( 1 ) 46 - 53 2010年09月
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Fad104, a positive regulator of adipogenesis, negatively regulates osteoblast differentiation.
Keishi Kishimoto, Ayumi Kato, Shigehiro Osada, Makoto Nishizuka, Masayoshi Imagawa
Biochemical and biophysical research communications 397 ( 2 ) 187 - 191 2010年06月
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TC10-like/TC10betaLong regulates adipogenesis by controlling mitotic clonal expansion.
Atsuko Kawaji, Makoto Nishizuka, Shigehiro Osada, Masayoshi Imagawa
Biological & pharmaceutical bulletin 33 ( 3 ) 404 - 409 2010年
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Repression of the promoter activity mediated by liver receptor homolog-1 through interaction with ku proteins.
Masae Ohno, Jun Komakine, Eiko Suzuki, Makoto Nishizuka, Shigehiro Osada, Masayoshi Imagawa
Biological & pharmaceutical bulletin 33 ( 5 ) 784 - 791 2010年
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Gelsolin, an actin regulatory protein, is required for differentiation of mouse 3T3-L1 cells into adipocytes.
Atsuko Kawaji, Yuki Ohnaka, Shigehiro Osada, Makoto Nishizuka, Masayoshi Imagawa
Biological & pharmaceutical bulletin 33 ( 5 ) 773 - 779 2010年
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Ku proteins function as corepressors to regulate farnesoid X receptor-mediated gene expression.
Masae Ohno, Masaaki Kunimoto, Makoto Nishizuka, Shigehiro Osada, Masayoshi Imagawa
Biochemical and biophysical research communications 390 ( 3 ) 738 - 742 2009年12月
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Fad24 causes hyperplasia in adipose tissue and improves glucose metabolism.
Yoshikazu Johmura, Kayoko Watanabe, Keishi Kishimoto, Takashi Ueda, Shoichi Shimada, Shigehiro Osada, Makoto Nishizuka, Masayoshi Imagawa
Biological & pharmaceutical bulletin 32 ( 10 ) 1656 - 1664 2009年10月
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The role of C/EBPdelta in the early stages of adipogenesis.
Tomoaki Hishida, Makoto Nishizuka, Shigehiro Osada, Masayoshi Imagawa
Biochimie 91 ( 5 ) 654 - 657 2009年05月
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Disruption of the novel gene fad104 causes rapid postnatal death and attenuation of cell proliferation, adhesion, spreading and migration.
Makoto Nishizuka, Keishi Kishimoto, Ayumi Kato, Masahito Ikawa, Masaru Okabe, Ryuichiro Sato, Hiroyuki Niida, Makoto Nakanishi, Shigehiro Osada, Masayoshi Imagawa
Experimental cell research 315 ( 5 ) 809 - 819 2009年03月
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A novel gene, fad49, plays a crucial role in the immediate early stage of adipocyte differentiation via involvement in mitotic clonal expansion.
Tomoaki Hishida, Tsuyoshi Eguchi, Shigehiro Osada, Makoto Nishizuka, Masayoshi Imagawa
The FEBS journal 275 ( 22 ) 5576 - 5588 2008年11月
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Wnt4 and Wnt5a promote adipocyte differentiation.
Makoto Nishizuka, Akiko Koyanagi, Shigehiro Osada, Masayoshi Imagawa
FEBS letters 582 ( 21-22 ) 3201 - 3205 2008年09月
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FAD24, a regulator of adipogenesis, is required for the regulation of DNA replication in cell proliferation.
Yoshikazu Johmura, Shigehiro Osada, Makoto Nishizuka, Masayoshi Imagawa
Biological & pharmaceutical bulletin 31 ( 6 ) 1092 - 1095 2008年06月
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Crucial roles of D-type cyclins in the early stage of adipocyte differentiation.
Tomoaki Hishida, Kumiko Naito, Shigehiro Osada, Makoto Nishizuka, Masayoshi Imagawa
Biochemical and biophysical research communications 370 ( 2 ) 289 - 294 2008年05月
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FAD24, a regulator of adipogenesis and DNA replication, inhibits H-RAS-mediated transformation by repressing NF-kappaB activity.
Yoshikazu Johmura, Masanori Suzuki, Shigehiro Osada, Makoto Nishizuka, Masayoshi Imagawa
Biochemical and biophysical research communications 369 ( 2 ) 464 - 470 2008年05月
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FAD24 acts in concert with histone acetyltransferase HBO1 to promote adipogenesis by controlling DNA replication.
Yoshikazu Johmura, Shigehiro Osada, Makoto Nishizuka, Masayoshi Imagawa
The Journal of biological chemistry 283 ( 4 ) 2265 - 2274 2008年01月
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peg10, an imprinted gene, plays a crucial role in adipocyte differentiation.
Tomoaki Hishida, Kumiko Naito, Shigehiro Osada, Makoto Nishizuka, Masayoshi Imagawa
FEBS letters 581 ( 22 ) 4272 - 4278 2007年09月
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SLC39A14, a LZT protein, is induced in adipogenesis and transports zinc.
Kei Tominaga, Takeshi Kagata, Yoshikazu Johmura, Tomoaki Hishida, Makoto Nishizuka, Masayoshi Imagawa
The FEBS journal 272 ( 7 ) 1590 - 1599 2005年04月
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Design, synthesis, and biological activity of novel PPARgamma ligands based on rosiglitazone and 15d-PGJ2.
Shinya Usui, Takayoshi Suzuki, Yoshifumi Hattori, Kazuma Etoh, Hiroki Fujieda, Makoto Nishizuka, Masayoshi Imagawa, Hidehiko Nakagawa, Kohfuku Kohda, Naoki Miyata
Bioorganic & medicinal chemistry letters 15 ( 6 ) 1547 - 1551 2005年03月
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Fad24, a mammalian homolog of Noc3p, is a positive regulator in adipocyte differentiation.
Kei Tominaga, Yoshikazu Johmura, Makoto Nishizuka, Masayoshi Imagawa
Journal of cell science 117 ( Pt 25 ) 6217 - 6226 2004年12月
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The novel gene fad104, containing a fibronectin type III domain, has a significant role in adipogenesis.
Kei Tominaga, Chiharu Kondo, Yoshikazu Johmura, Makoto Nishizuka, Masayoshi Imagawa
FEBS letters 577 ( 1-2 ) 49 - 54 2004年11月
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Development of a Competitive Enzyme Immunoassay for Detection of Capacity of Chemicals to Bind Quail Estrogen Receptor alpha and beta
Maekawa S., Nishizuka M., Heitaku S., Kunimoto M., Nishikawa J., Ichikawa K., Shimada K., Imagawa M
Journal of Health Science 50 ( 1 ) 25 - 32 2004年10月
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Evaluation of Ability of Chemicals to Bind Frog (Xenopus laevis) Estrogen Receptor by in Vitro Binding Assay
Suzuki E., Kunimoto M., Nishizuka M., Imagawa M.
Journal of Health Science 50 ( 6 ) 685 - 688 2004年08月
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The novel gene fad158, having a transmembrane domain and leucine-rich repeat, stimulates adipocyte differentiation.
Kei Tominaga, Chiharu Kondo, Takeshi Kagata, Tomoaki Hishida, Makoto Nishizuka, Masayoshi Imagawa
The Journal of biological chemistry 279 ( 33 ) 34840 - 34848 2004年08月
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Development of Standardized in Vitro Assay System for Estrogen Receptors and Species Specificity of Binding Ability of 4-Nonylphenol and p-Octylphenol.
Nishizuka M., Heitaku S., Maekawa S., Nishikawa J., Imagawa M.
Journal of Health Science 50 ( 5 ) 511 - 517 2004年07月
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Isolation of Genes Regulated by Peroxisome Proliferator-Activated Receptor gamma (PPARgamma) by Two-Dimensional Electrophoresis and Mass Spectrometer
Tsuchiya S., Arimoto E., Nishizuka M., Taguchi R., Imagawa M.
Journal of Health Science 50 ( 3 ) 257 - 263 2004年02月
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Crucial role of TCL/TC10beta L, a subfamily of Rho GTPase, in adipocyte differentiation.
Makoto Nishizuka, Emi Arimoto, Tomoko Tsuchiya, Tsutomu Nishihara, Masayoshi Imagawa
The Journal of biological chemistry 278 ( 17 ) 15279 - 15284 2003年04月
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脂肪細胞分化初期に発現が変動する遺伝子群の単離および機能解析
西塚 誠
2003年03月
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Isolation of up- or down-regulated genes in PPARgamma-expressing NIH-3T3 cells during differentiation into adipocytes.
Masaaki Okuno, Emi Arimoto, Makoto Nishizuka, Tsutomu Nishihara, Masayoshi Imagawa
FEBS letters 519 ( 1-3 ) 108 - 112 2002年05月
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Induction of Bach1 and ARA70 gene expression at an early stage of adipocyte differentiation of mouse 3T3-L1 cells.
Makoto Nishizuka, Tomoko Tsuchiya, Tsutomu Nishihara, Masayoshi Imagawa
The Biochemical journal 361 ( Pt 3 ) 629 - 633 2002年02月
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Expression of p68 RNA helicase is closely related to the early stage of adipocyte differentiation of mouse 3T3-L1 cells.
A Kitamura, M Nishizuka, K Tominaga, T Tsuchiya, T Nishihara, M Imagawa
Biochemical and biophysical research communications 287 ( 2 ) 435 - 439 2001年09月
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RGS2 promotes adipocyte differentiation in the presence of ligand for peroxisome proliferator-activated receptor gamma.
M Nishizuka, K Honda, T Tsuchiya, T Nishihara, M Imagawa
The Journal of biological chemistry 276 ( 32 ) 29625 - 29627 2001年08月