Papers - KON Tomoya
-
SNCA and TPPP transcripts increase in oligodendroglial cytoplasmic inclusions in multiple system atrophy.
Tomoya Kon, Shelley L Forrest, Seojin Lee, Jun Li, Helen Chasiotis, Nasna Nassir, Mohammed J Uddin, Anthony E Lang, Gabor G Kovacs
Neurobiology of disease 198 106551 - 106551 2024.8
-
Multiple system atrophy with amyloid-β-predominant Alzheimer's disease neuropathologic change.
Tomoya Kon, Shojiro Ichimata, Daniel G Di Luca, Ivan Martinez-Valbuena, Ain Kim, Koji Yoshida, Abdullah A Alruwaita, Galit Kleiner, Antonio P Strafella, Shelley L Forrest, Christine Sato, Ekaterina Rogaeva, Susan H Fox, Anthony E Lang, Gabor G Kovacs
Brain communications 6 ( 3 ) fcae141 2024.5
-
Molecular Behavior of α-Synuclein Is Associated with Membrane Transport, Lipid Metabolism, and Ubiquitin-Proteasome Pathways in Lewy Body Disease.
Tomoya Kon, Seojin Lee, Ivan Martinez-Valbuena, Koji Yoshida, Satoshi Tanikawa, Anthony E Lang, Gabor G Kovacs
International journal of molecular sciences 25 ( 5 ) 2024.3
-
Neuronal SNCA transcription during Lewy body formation.
Tomoya Kon, Shelley L Forrest, Seojin Lee, Ivan Martinez-Valbuena, Jun Li, Nasna Nassir, Mohammed J Uddin, Anthony E Lang, Gabor G Kovacs
Acta neuropathologica communications 11 ( 1 ) 185 - 185 2023.11
-
Accumulation of Nonfibrillar TDP-43 in the Rough Endoplasmic Reticulum Is the Early-Stage Pathology in Amyotrophic Lateral Sclerosis.
Tomoya Kon, Fumiaki Mori, Kunikazu Tanji, Yasuo Miki, Haruo Nishijima, Takashi Nakamura, Iku Kinoshita, Chieko Suzuki, Hidekachi Kurotaki, Masahiko Tomiyama, Koichi Wakabayashi
Journal of neuropathology and experimental neurology 81 ( 4 ) 271 - 281 2022.3
-
Relationship between promyelocytic leukemia protein nuclear bodies and TAR DNA-binding protein-43 aggregation in spinal anterior horn cells in sporadic amyotrophic lateral sclerosis
Fumiaki Mori, Tomoya Kon, Riho Itazawa, Ami Akatsu, Yasuo Miki, Akira Arai, Hidekachi Kurotaki, Masahiko Tomiyama, Koichi Wakabayashi
Journal of Neuropathology & Experimental Neurology 2026.4
-
Efficacy of 42-month oral administration of glucoraphanin in preventing cognitive decline in individuals at elevated risk of dementia, including those with mild cognitive impairment: a randomized, double-blind, placebo-controlled pilot study.
Shimizu S, Kasai S, Suzuki C, Kon T, Suganuma H, Suzuki S, Murashita K, Nakaji S, Ihara K, Tomiyama M, Itoh K
Frontiers in nutrition 13 1740494 2026
-
Pathological and Molecular Insights into the Early Stage of Multiple System Atrophy
Makoto T. Tanaka, Yasuo Miki, Tomoya Kon, Fumiaki Mori, Koichi Wakabayashi
Cells 14 ( 24 ) 1740494 2025.12
-
Abnormal α-synuclein binds to synaptotagmin 13, impairing extracellular vesicle release in synucleinopathies
Miki, Y; Shimoyama, S; Tanaka, MT; Kushibiki, H; Nakahara, A; Wen, XP; Hijioka, M; Kon, T; Murthy, M; Furukawa, T; Bettencourt, C; Mori, F; Mizukami, H; Takahashi, S; Tada, M; Kitamura, Y; Kakita, A; Warner, TT; Wakabayashi, K
TRANSLATIONAL NEURODEGENERATION 14 ( 1 ) 32 2025.6
-
Progressive Respiratory Failure in an Autopsy Case of Amyotrophic Lateral Sclerosis With Cardiac and Pulmonary Amyloidosis
Nakamura, T; Kon, T; Goto, S; Nishijima, H; Suzuki, C; Mori, F; Wakabayashi, K; Tomiyama, M
NEUROLOGY AND CLINICAL NEUROSCIENCE 2025.4
-
Co-Expression of Tardive Dyskinesia and Drug-Induced Parkinsonism in Rats Chronically Treated With Haloperidol.
Kinoshita I, Nishijima H, Nakamura T, Kon T, Shimoyama S, Hikichi H, Suzuki C, Tomiyama M
Neuropsychopharmacology reports 45 ( 1 ) e12524 2025.3
-
Co-pathologies modify hippocampal protein accumulation patterns in neurodegenerative diseases
Yoshida, K; Forrest, SL; Ichimata, S; Tanaka, H; Kon, T; Kovacs, GG
ALZHEIMERS & DEMENTIA 2024.12
-
Biomarker-Based Approach to α-Synucleinopathies: Lessons from Neuropathology
Kovacs, GG; Grinberg, LT; Halliday, G; Alafuzoff, I; Dugger, BN; Murayama, S; Forrest, SL; Martinez-Valbuena, I; Tanaka, H; Kon, T; Yoshida, K; Jaunmuktane, Z; Spina, S; Nelson, PT; Gentleman, S; Alegre-Abarrategui, J; Serrano, GE; Paes, VR; Takao, M; Wakabayashi, K; Uchihara, T; Yoshida, M; Saito, Y; Kofler, J; Rodriguez, RD; Gelpi, E; Attems, J; Crary, JF; Seeley, WW; Duda, JE; Keene, CD; Woulfe, J; Munoz, D; Smith, C; Lee, EB; Neumann, M; White, CL; Mckee, AC; Thal, DR; Jellinger, K; Ghetti, B; Mackenzie, IRA; Dickson, DW; Beach, TG
MOVEMENT DISORDERS 2024.10
-
Intranasal administration of trehalose reduces α-synuclein oligomers and accelerates α-synuclein aggregation.
Makoto T Tanaka, Yasuo Miki, Fumiaki Mori, Tomoya Kon, Tomonori Furukawa, Shuji Shimoyama, Yota Tatara, Taku Ozaki, Conceição Bettencourt, Thomas T Warner, Koichi Wakabayashi
Brain communications 6 ( 4 ) fcae193 2024.8
-
Revisiting the relevance of Hirano bodies in neurodegenerative diseases.
Koji Yoshida, Shelley L Forrest, Shojiro Ichimata, Hidetomo Tanaka, Tomoya Kon, Maria Carmela Tartaglia, Charles H Tator, Anthony E Lang, Naoki Nishida, Gabor G Kovacs
Neuropathology and applied neurobiology 50 ( 2 ) e12978 2024.4
-
Colocalization of TDP-43 and stress granules at the early stage of TDP-43 aggregation in amyotrophic lateral sclerosis.
Fumiaki Mori, Hina Yasui, Yasuo Miki, Tomoya Kon, Akira Arai, Hidekachi Kurotaki, Masahiko Tomiyama, Koichi Wakabayashi
Brain pathology (Zurich, Switzerland) 34 ( 2 ) e13215 2024.3
-
Dynamic change of synuclein transcription during Lewy body formation
Kon, T; Forrest, S; Lee, S; Martinez-Valbuena, I; Li, J; Lang, AE; Kovacs, GG
BRAIN PATHOLOGY 33 2023.9
-
Axon terminal hypertrophy of striatal projection neurons with levodopa-induced dyskinesia priming.
Takashi Nakamura, Haruo Nishijima, Fumiaki Mori, Iku Kinoshita, Tomoya Kon, Chieko Suzuki, Koichi Wakabayashi, Masahiko Tomiyama
Frontiers in neuroscience 17 1169336 - 1169336 2023.6
-
Altered Amantadine Effects after Repetitive Treatment for l-dopa-induced Involuntary Movements in a Rat Model of Parkinson's Disease.
Yoshiki Murakami, Haruo Nishijima, Takashi Nakamura, Tomonori Furukawa, Iku Kinoshita, Tomoya Kon, Chieko Suzuki, Masahiko Tomiyama
Neuroscience letters 806 137248 - 137248 2023.5
-
‹一般演題抄録›パーキンソン病モデルラットにおけるアマンタジンの治療効果は反復投与により変動する
村上 佳生, 西嶌 春生, 中村 崇志, 木下 郁, 今 智矢, 鈴木 千恵子, 冨山 誠彦
弘前医学 73 ( 1-4 ) 106 2023.3