Affiliation
Graduate School of Medicine Medical Science Course Endocorinology and Metabolism
Date of Birth
1989
OSONOI Sho
Degree
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Doctor (Medicine)
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医学士
Papers
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A diabetic patient with finger gangrene.
Osonoi S, Hamaura K, Murakami H
European journal of internal medicine 2022.5
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Islet microangiopathy and augmented beta-cell loss in Japanese non-obese type 2 diabetes patients who died of acute myocardial infarction
Takahashi Kazuhisa, Mizukami Hiroki, Osonoi Sho, Takeuchi Yuki, Kudoh Kazuhiro, Sasaki Takanori, Daimon Makoto, Yagihashi Soroku
JOURNAL OF DIABETES INVESTIGATION 12 ( 12 ) 2149 - 2161 2021.12
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Diabetes in Humans Activates Pancreatic Stellate Cells via RAGE in Pancreatic Ductal Adenocarcinoma
Uchida Chiaki, Mizukami Hiroki, Hara Yutaro, Saito Takeshi, Umetsu Satoko, Igawa Akiko, Osonoi Sho, Kudoh Kazuhiro, Yamamoto Yasuhiko, Yamamoto Hiroshi, Yagihashi Soroku, Hakamada Kenichi
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 ( 21 ) 2021.11
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MEK/ERK Signaling in beta-Cells Bifunctionally Regulates beta-Cell Mass and Glucose-Stimulated Insulin Secretion Response to Maintain Glucose Homeostasis
Ikushima Yoshiko Matsumoto, Awazawa Motoharu, Kobayashi Naoki, Osonoi Sho, Takemiya Seiichi, Kobayashi Hiroshi, Suwanai Hirotsugu, Morimoto Yuichi, Soeda Kotaro, Adachi Jun, Muratani Masafumi, Charron Jean, Mizukami Hiroki, Takahashi Noriko, Ueki Kohjiro
DIABETES 70 ( 7 ) 1519 - 1535 2021.7
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Inhibitory effects of xanthine oxidase inhibitor, topiroxostat, on development of neuropathy in db/db mice
Takahashi Kazuhisa, Mizukami Hiroki, Osonoi Sho, Ogasawara Saori, Hara Yutaro, Kudoh Kazuhiro, Takeuchi Yuki, Sasaki Takanori, Daimon Makoto, Yagihashi Soroku
NEUROBIOLOGY OF DISEASE 155 105392 2021.7
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Collateral Glucose-Utlizing Pathwaya in Diabetic Polyneuropathy
Mizukami Hiroki, Osonoi Sho
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 ( 1 ) 2021.1
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Increased Oxidative Stress Underlies Abnormal Pain Threshold in a Normoglycemic Japanese Population
Osonoi Sho, Mizukami Hiroki, Itabashi Chieko, Wada Kanichiro, Kudoh Kazuhiro, Igawa Akiko, Ogasawara Saori, Ishibashi Yasuyuki, Daimon Makoto, Yagihashi Soroku, Nakaji Shigeyuki
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 21 ( 21 ) 2020.11
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Beneficial effects of combination therapy of canagliflozin and teneligliptin on diabetic polyneuropathy and ?-cell volume density in spontaneously type 2 diabetic Goto-Kakizaki rats
Guo Danyang, Mizukami Hiroki, Osonoi Sho, Takahashi Kazuhisa, Ogasawara Saori, Kudo Kazuhiro, Sasaki Takanori, Yagihashi Soroku
METABOLISM-CLINICAL AND EXPERIMENTAL 107 154232 2020.6
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Biphasic changes in beta-cell mass around parturition are accompanied by increased serotonin production
Takahashi Masaya, Miyatsuka Takeshi, Suzuki Luka, Osonoi Sho, Himuro Miwa, Miura Masaki, Katahira Takehiro, Wakabayashi Yuka, Fukunaka Ayako, Nishida Yuya, Fujitani Yoshio, Takeda Satoru, Mizukami Hiroki, Itakura Atsuo, Watada Hirotaka
SCIENTIFIC REPORTS 10 ( 1 ) 4962 2020.3
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Normal High HbA1c a Risk Factor for Abnormal Pain Threshold in the Japanese Population (vol 10, 651, 2019)
Itabashi Chieko, Mizukami Hiroki, Osonoi Sho, Takahashi Kazuhisa, Kudo Kazuhiro, Wada Kanichiro, Inaba Wataru, Guo Danyang, Uchida Chiaki, Umetsu Satoko, Igawa Akiko, Ogasawara Saori, Ryuzaki Masaki, Komeda Kouji, Ishibashi Yasuyuki, Yagihashi Soroku, Nakaji Shigeyuki
FRONTIERS IN ENDOCRINOLOGY 11 130 2020.3
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Serotonin Regulates Adult β-Cell Mass by Stimulating Perinatal β-Cell Proliferation.
Joon Ho Moon, Yeong Gi Kim, Kyuho Kim, Sho Osonoi, Shuang Wang, Diane C Saunders, Juehu Wang, Katherine Yang, Hyeongseok Kim, Junguee Lee, Ji-Seon Jeong, Ronadip R Banerjee, Seung K Kim, Yingjie Wu, Hiroki Mizukami, Alvin C Powers, Michael S German, Hail Kim
Diabetes 69 ( 2 ) 205 - 214 2020.2
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Diabetes, an independent poor prognostic factor of non-B non-C hepatocellular carcinoma, correlates with dihydropyrimidinase-like 3 promoter methylation
Umetsu Satoko, Mizukami Hiroki, Saito Takeshi, Uchida Chiaki, Igawa Akiko, Kudo Kazuhiro, Itabashi Chieko, Osonoi Sho, Guo Danyang, Sasaki Takanori, Yagihashi Soroku, Hakamada Kenichi
SCIENTIFIC REPORTS 10 ( 1 ) 1156 2020.1
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Lipopolysaccharide-binding protein is a distinctive biomarker of abnormal pain threshold in the general Japanese population
Kudoh Kazuhiro, Mizukami Hiroki, Itabashi Chieko, Fuke Nobuo, Osonoi Sho, Takeuchi Yuki, Wada Kanichiro, Igawa Akiko, Ogasawara Saori, Ishibashi Yasuyuki, Hakamada Kenichi, Yagihashi Soroku, Nakaji Shigeyuki
BMJ OPEN DIABETES RESEARCH & CARE 8 ( 1 ) 2020
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Role of glucosamine in development of diabetic neuropathy independent of the aldose reductase pathway
Hiroki Mizukami, Sho Osonoi, Shizuka Takaku, Shin-Ichiro Yamagishi, Saori Ogasawara, Kazunori Sango, Sookja Chung, Soroku Yagihashi
Brain Communications 2 ( 2 ) fcaa168 2020
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Normal High HbA1c a Risk Factor for Abnormal Pain Threshold in the Japanese Population.
Chieko Itabashi, Hiroki Mizukami, Sho Osonoi, Kazuhisa Takahashi, Kazuhiro Kudo, Kanichiro Wada, Wataru Inaba, Guo Danyang, Chiaki Uchida, Satoko Umetsu, Akiko Igawa, Saori Ogasawara, Masaki Ryuzaki, Kouji Komeda, Yasuyuki Ishibashi, Soroku Yagihashi, Shigeyuki Nakaji
Frontiers in endocrinology 10 651 - 651 2019
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Lower serum calcium levels are a risk factor fora decrease in eGFR in a general non-chronic kidney disease population
Mizushiri Satoru, Daimon Makoto, Murakami Hiroshi, Kamba Aya, Osonoi Sho, Yamaichi Masato, Matsumura Koki, Tanabe Jutaro, Matsuhashi Yuki, Yanagimachi Miyuki, Tokuda Itoy, Kurauchi Shizuka, Sawada Kaori
SCIENTIFIC REPORTS 8 ( 1 ) 14213 2018.9
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Dominance of the hypothalamus-pituitary-adrenal axis over the renin-angiotensin-aldosterone system is a risk factor for decreased insulin secretion
Daimon Makoto, Kamba Aya, Murakami Hiroshi, Mizushiri Satoru, Osonoi Sho, Matsuki Kota, Sato Eri, Tanabe Jutaro, Takayasu Shinobu, Matsuhashi Yuki, Yanagimachi Miyuki, Terui Ken, Kageyama Kazunori, Tokuda Itoyo, Kurauchi Shizuka, Nakaji Shigeyuki
SCIENTIFIC REPORTS 7 ( 1 ) 11360 2017.9
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Association between serum prolactin levels and insulin resistance in non-diabetic men
Daimon Makoto, Kamba Aya, Murakami Hiroshi, Mizushiri Satoru, Osonoi Sho, Yamaichi Masato, Matsuki Kota, Sato Eri, Tanabe Jutaro, Takayasu Shinobu, Matsuhashi Yuki, Yanagimachi Miyuki, Terui Ken, Kageyama Kazunori, Tokuda Itoyo, Takahashi Ippei, Nakaji Shigeyuki
PLOS ONE 12 ( 4 ) e0175204 2017.4
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Involvement of Oxidative Stress-Induced DNA Damage, Endoplasmic Reticulum Stress, and Autophagy Deficits in the Decline of beta-Cell Mass in Japanese Type 2 Diabetic Patients
Mizukami Hiroki, Takahashi Kazunori, Inaba Wataru, Tsuboi Kentaro, Osonoi Sho, Yoshida Taro, Yagihashi Soroku
DIABETES CARE 37 ( 7 ) 1966 - 1974 2014.7
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Age-associated changes of islet endocrine cells and the effects of body mass index in Japanese
Hiroki Mizukami, Kazunori Takahashi, Wataru Inaba, Sho Osonoi, Kosuke Kamata, Kentaro Tsuboi, Soroku Yagihashi
Journal of Diabetes Investigation 5 ( 1 ) 38 - 47 2013.8
Awards
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第1回弘前メディカルサイエンスフォーラム最優秀賞
2019.11
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令和元年度糖尿病性神経障害を考える会学術講演会優秀演題賞
2019.08