Updated on 2024/03/28

写真a

 
MIYAZAKI WATARU
 
Affiliation
Health Sciences Health Sciences(Doctoral Course) Department of Bioscience and Laboratory Medicine

Degree

  • 博士(医学)

Research Interests

  • 脳発達

  • 環境化学物質

  • 毒性学

  • 内分泌撹乱化学物質

Research Areas

  • Life Science / Hygiene and public health (laboratory)

  • Life Science / Hygiene and public health (laboratory)

  • Life Science / Hygiene and public health (laboratory)

  • Life Science / Hygiene and public health (non-laboratory)

  • Life Science / Hygiene and public health (non-laboratory)

  • Life Science / Physiology

  • Environmental Science/Agriculture Science / Radiation influence

  • Life Science / Clinical pharmacy

  • Environmental Science/Agriculture Science / Chemical substance influence on environment

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Professional Memberships

  • 日本衛生学会

  • 日本生理学会

  • 日本内分泌撹乱化学物質学会

  • Endocrine Society

  • Japan Society of Endocrine Disrupter Research

  • THE JAPANESE SOCIETY FOR HYGIENE

  • THE PHYSIOLOGICAL SOCIETY OF JAPAN

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Papers

  • Motor coordination is partially impaired in neonatal mice with moderate hypothyroidism but not with mild hypothyroidism

    Michifumi Kokubo, Izuki Amano, Hiroyuki Yajima, Wataru Miyazaki, Yusuke Takatsuru, Asahi Haijima, Shogo Haraguchi, Noriyuki Koibuchi

    Thyroid Science   1 ( 1 )   100005 - 100005   2024.2

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    Language:English   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Effects of Perfluorooctane Sulfonate on Cerebellar Cells via Inhibition of Type 2 Iodothyronine Deiodinase Activity

    Yuki Fujiwara, Yuhei Miyasaka, Ayane Ninomiya, Wataru Miyazaki, Toshiharu Iwasaki, Winda Ariyani, Izuki Amano, Noriyuki Koibuchi

    International Journal of Molecular Sciences   24 ( 16 )   2023.8

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    PubMed

  • Effects of cadmium-metallothionein complex exposure on bone tissue through kidney injury

    YAMANAKA Tomoki, YAMAMOTO Katsuya, ISHIDA Keishi, MATSUMARU Daisuke, MIYAZAKI Wataru, NAKANISHI Tsuyoshi

    Annual Meeting of the Japanese Society of Toxicology   50.1 ( 0 )   P1-052S   2023

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    CiNii Research

  • Gadolinium-based contrast agent accelerates the migration of astrocyte via integrin αvβ3 signaling pathway

    Winda Ariyani, Wataru Miyazaki, Yoshito Tsushima, Noriyuki Koibuchi

    Scientific Reports   12 ( 1 )   5850   2022.12

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    PubMed

  • Involvement of integrin αvβ3 in thyroid hormone-induced dendritogenesis

    Winda Ariyani, Wataru Miyazaki, Izuki Amano, Noriyuki Koibuchi

    Frontiers in Endocrinology   13   938596   2022.8

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    PubMed

  • A Novel Role of Nuclear and Membrane Receptor on Isoflavone-Induced Neuritogenesis and Synaptogenesis

    Winda Ariyani, Wataru Miyazaki, Noriyuki Koibuchi

    Journal of the Endocrine Society   5 ( Supplement_1 )   A802 - A803   2021.5

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  • Absence of Thyroid Hormone Induced Delayed Dendritic Arborization in Mouse Primary Hippocampal Neurons Through Insufficient Expression of Brain-Derived Neurotrophic Factor

    Hiroyuki Yajima, Izuki Amano, Sumiyasu Ishii, Tetsushi Sadakata, Wataru Miyazaki, Yusuke Takatsuru, Noriyuki Koibuchi

    Frontiers in Endocrinology   12   629100   2021.2

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    PubMed

  • Soy Isoflavones Accelerate Glial Cell Migration via GPER-Mediated Signal Transduction Pathway.

    Winda Ariyani, Wataru Miyazaki, Izuki Amano, Kenji Hanamura, Tomoaki Shirao, Noriyuki Koibuchi

    Frontiers in endocrinology   11   554941 - 554941   2020.11

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    PubMed

  • Neurotoxic effects of lactational exposure to perfluorooctane sulfonate on learning and memory in adult male mouse

    Abdallah Mshaty, Asahi Haijima, Yusuke Takatsuru, Ayane Ninomiya, Hiroyuki Yajima, Michifumi Kokubo, Miski Aghnia Khairinisa, Wataru Miyazaki, Izuki Amano, Noriyuki Koibuchi

    Food and Chemical Toxicology   145   111710 - 111710   2020.11

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    PubMed

  • Neurotoxic effects of lactational exposure to perfluorooctane sulfonate on learning and memory in adult male mouse

    Abdallah Mshaty, Asahi Haijima, Yusuke Takatsuru, Ayane Ninomiya, Hiroyuki Yajima, Michifumi Kokubo, Miski Aghnia Khairinisa, Wataru Miyazaki, Izuki Amano, Noriyuki Koibuchi

    Food and Chemical Toxicology   2020.8

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    Language:English   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • SAT-708 The Effect of Soybean Isoflavones in Developing Cerebellum

    Winda Ariyani, Wataru Miyazaki, Izuki Amano, Noriyuki Koibuchi

    Journal of the Endocrine Society   4 ( Supplement_1 )   2020.5

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  • 甲状腺ホルモン受容体による小脳プルキンエ細胞におけるシナプス可塑性の調節機構

    二ノ宮 彩音, 細井 延武, 小久保 倫文, 天野 出月, はい島 旭, 宮崎 航, 平井 宏和, 鯉淵 典之

    日本内分泌学会雑誌   95 ( 4 )   1342 - 1342   2020.2

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • 周産期中等度甲状腺機能低下が協調運動機能に与える影響

    小久保 倫文, 天野 出月, 宮崎 航, 高鶴 裕介, 配島 旭, 原口 省吾, 鯉淵 典之

    日本内分泌学会雑誌   95 ( 4 )   1342 - 1342   2020.2

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  • A Novel Mechanism of S-equol Action in Neurons and Astrocytes: The Possible Involvement of GPR30/GPER1.

    Ariyani W, Miyazaki W, Koibuchi N.

    International Journal of Molecular Sciences   2019.10

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  • A Novel Mechanism of S-equol Action in Neurons and Astrocytes: The Possible Involvement of GPR30/GPER1.

    Ariyani W, Miyazaki W, Koibuchi N

    International journal of molecular sciences   20 ( 20 )   5178 - 5178   2019.10

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    PubMed

  • Gadolinium-based contrast agents toxicity in animal studies.

    Khairinisa MA, Amano I, Miyazaki W, Koibuchi N, Tsushima Y

    Magnetic resonance imaging   62   57 - 58   2019.10

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    PubMed

  • Gadolinium-based contrast agents toxicity in animal studies.

    Miski A Khairinisa, Izuki Amano, Wataru Miyazaki, Noriyuki Koibuchi, Yoshito Tsushima

    Magnetic resonance imaging   2019.5

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  • A Possible Novel Mechanism of Action of Genistein and Daidzein for Activating Thyroid Hormone Receptor-Mediated Transcription.

    Winda Ariyani, Toshiharu Iwasaki, Wataru Miyazaki, Lu Yu, Shigeki Takeda, Noriyuki Koibuchi

    Toxicological sciences : an official journal of the Society of Toxicology   164 ( 2 )   417 - 427   2018.8

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    Language:English   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • In Utero and Postnatal Propylthiouracil-Induced Mild Hypothyroidism Impairs Maternal Behavior in Mice.

    Miski Aghnia Khairinisa, Yusuke Takatsuru, Izuki Amano, Michifumi Kokubo, Asahi Haijima, Wataru Miyazaki, Noriyuki Koibuchi

    Frontiers in endocrinology   9   228 - 228   2018.5

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  • The Effects of Low-Dose Bisphenol A and Bisphenol F on Neural Differentiation of a Fetal Brain-Derived Neural Progenitor Cell Line.

    Yuki Fujiwara, Wataru Miyazaki, Noriyuki Koibuchi, Takahiko Katoh

    Frontiers in endocrinology   9   24 - 24   2018.2

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  • Effects of Gadolinium-Based Contrast Agents on Thyroid Hormone Receptor Action and Thyroid Hormone-Induced Cerebellar Purkinje Cell Morphogenesis.

    Winda Ariyani, Toshiharu Iwasaki, Wataru Miyazaki, Erdene Khongorzul, Takahito Nakajima, Satomi Kameo, Hiroshi Koyama, Yoshito Tsushima, Noriyuki Koibuchi

    Frontiers in endocrinology   7   115 - 115   2016.8

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  • Prenatal exposure to bisphenol A impacts neuronal morphology in the hippocampal CA1 region in developing and aged mice.

    Eiki Kimura, Chieri Matsuyoshi, Wataru Miyazaki, Seico Benner, Mayuko Hosokawa, Kazuhito Yokoyama, Masaki Kakeyama, Chiharu Tohyama

    Archives of toxicology   90 ( 3 )   691 - 700   2016.3

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  • The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the development and function of the blood-brain barrier.

    Wataru Miyazaki, Yuki Fujiwara, Takahiko Katoh

    Neurotoxicology   52   64 - 71   2016.1

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  • [Application of Metabolomics to Multiple Chemical Sensitivity Research].

    Takahiko Katoh, Yuki Fujiwara, Chihiro Nakashita, Xi Lu, Aya Hisada, Wataru Miyazaki, Kenichi Azuma, Mari Tanigawa, Iwao Uchiyama, Naoki Kunugita

    Nihon eiseigaku zasshi. Japanese journal of hygiene   71 ( 1 )   94 - 99   2016

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Survey on the Awareness of Genetic Testing in Japanese Workers: The Effect of Participant Characteristics on Awareness.

    Chihiro Nakashita, Yuki Fujiwara, Xi Lu, Aya Hisada, Wataru Miyazaki, Takahiko Katoh

    Nihon eiseigaku zasshi. Japanese journal of hygiene   71 ( 2 )   133 - 137   2016

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  • Genetic and Environmental Risk Factors, Sleeping Environment, for Allergic Diseases in Infant: Analysis of a Data Subset from the South Kyushu and Okinawa Study Area of Japan Environment and Children's Study.

    Wataru Miyazaki, Xi Lu, Masako Oda, Yoshiki Kuroda, Kazuo Aoki, Hiroshi Mitsubuchi, Takashi Ohba, Takahiko Katoh

    Nihon eiseigaku zasshi. Japanese journal of hygiene   71 ( 2 )   138 - 148   2016

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  • Associations between estrogen receptor genetic polymorphisms, smoking status, and prostate cancer risk: a case-control study in Japanese men.

    Xi Lu, Yuko Yamano, Hiroyuki Takahashi, Masahide Koda, Yuki Fujiwara, Aya Hisada, Wataru Miyazaki, Takahiko Katoh

    Environmental health and preventive medicine   20 ( 5 )   332 - 337   2015.9

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  • Association between airflow limitation severity and arterial stiffness as determined by the brachial-ankle pulse wave velocity: a cross-sectional study.

    Masako Oda, Hisamitsu Omori, Ayumi Onoue, Xiaoyi Cui, Xi Lu, Hironori Yada, Aya Hisada, Wataru Miyazaki, Noritaka Higashi, Yasuhiro Ogata, Takahiko Katoh

    Internal medicine (Tokyo, Japan)   54 ( 20 )   2569 - 2575   2015

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  • Prevalence and interannual changes in multiple chemical sensitivity in Japanese workers.

    Xiaoyi Cui, Xi Lu, Mizue Hiura, Masako Oda, Aya Hisada, Wataru Miyazaki, Hisamitsu Omori, Takahiko Katoh

    Environmental health and preventive medicine   19 ( 3 )   215 - 219   2014.5

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  • Disruption of paired-associate learning in rat offspring perinatally exposed to dioxins.

    Masaki Kakeyama, Toshihiro Endo, Yan Zhang, Wataru Miyazaki, Chiharu Tohyama

    Archives of toxicology   88 ( 3 )   789 - 798   2014.3

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  • Association of genotypes of carcinogen-metabolizing enzymes and smoking status with bladder cancer in a Japanese population.

    Xiaoyi Cui, Xi Lu, Mizue Hiura, Hisamitsu Omori, Wataru Miyazaki, Takahiko Katoh

    Environmental health and preventive medicine   18 ( 2 )   136 - 142   2013.3

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  • Evaluation of genetic polymorphisms in patients with multiple chemical sensitivity.

    Xiaoyi Cui, Xi Lu, Mizue Hiura, Masako Oda, Wataru Miyazaki, Takahiko Katoh

    PloS one   8 ( 8 )   e73708 - e73708   2013

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  • Effects of temperament and character profiles on state and trait depression and anxiety: a prospective study of a Japanese youth population.

    Xi Lu, Zi Chen, Xiaoyi Cui, Masayo Uji, Wataru Miyazaki, Masako Oda, Toshiaki Nagata, Toshinori Kitamura, Takahiko Katoh

    Depression research and treatment   2012   604684 - 604684   2012

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  • Automated test of behavioral flexibility in mice using a behavioral sequencing task in IntelliCage.

    Toshihiro Endo, Fumihiko Maekawa, Vootele Võikar, Asahi Haijima, Yukari Uemura, Yan Zhang, Wataru Miyazaki, Shigetomo Suyama, Kuniko Shimazaki, David P Wolfer, Toshihiko Yada, Chiharu Tohyama, Hans-Peter Lipp, Masaki Kakeyama

    Behavioural brain research   221 ( 1 )   172 - 181   2011.8

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  • Disruption of thyroid hormone receptor-mediated transcription and thyroid hormone-induced Purkinje cell dendrite arborization by polybrominated diphenyl ethers.

    Kingsley Ibhazehiebo, Toshiharu Iwasaki, Junko Kimura-Kuroda, Wataru Miyazaki, Noriaki Shimokawa, Noriyuki Koibuchi

    Environmental health perspectives   119 ( 2 )   168 - 175   2011.2

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  • In utero and lactational exposure to low doses of chlorinated and brominated dioxins induces deficits in the fear memory of male mice.

    Asahi Haijima, Toshihiro Endo, Yan Zhang, Wataru Miyazaki, Masaki Kakeyama, Chiharu Tohyama

    Neurotoxicology   31 ( 4 )   385 - 390   2010.8

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  • Hydroxylated PCB induces Ca2+ oscillations and alterations of membrane potential in cultured cortical cells.

    Marina Londoño, Noriaki Shimokawa, Wataru Miyazaki, Toshiharu Iwasaki, Noriyuki Koibuchi

    Journal of applied toxicology : JAT   30 ( 4 )   334 - 342   2010.5

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  • The effect of hydroxylated polychlorinated biphenyl (OH-PCB) on thyroid hormone receptor (TR)-mediated transcription through native-thyroid hormone response element (TRE).

    Izuki Amano, Wataru Miyazaki, Toshiharu Iwasaki, Noriaki Shimokawa, Noriyuki Koibuchi

    Industrial health   48 ( 1 )   115 - 118   2010

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  • Retinoic Acid receptor-related orphan receptor alpha-enhanced thyroid hormone receptor-mediated transcription requires its ligand binding domain which is not, by itself, sufficient: possible direct interaction of two receptors.

    Chun-Hong Qiu, Wataru Miyazaki, Toshiharu Iwasaki, Marina Londoño, Kingsley Ibhazehiebo, Noriaki Shimokawa, Noriyuki Koibuchi

    Thyroid : official journal of the American Thyroid Association   19 ( 8 )   893 - 898   2009.8

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  • Activation of aromatase expression by retinoic acid receptor-related orphan receptor (ROR) alpha in breast cancer cells: identification of a novel ROR response element.

    Hiroki Odawara, Toshiharu Iwasaki, Jun Horiguchi, Nana Rokutanda, Kazumi Hirooka, Wataru Miyazaki, Yukio Koibuchi, Noriaki Shimokawa, Yuichi Iino, Izumi Takeyoshi, Noriyuki Koibuchi

    The Journal of biological chemistry   284 ( 26 )   17711 - 17719   2009.6

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  • Liquid chemiluminescent DNA pull-down assay to measure nuclear receptor-DNA binding in solution.

    Toshiharu Iwasaki, Wataru Miyazaki, Nana Rokutanda, Noriyuki Koibuchi

    BioTechniques   45 ( 4 )   445 - 448   2008.10

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  • Identification of the functional domain of thyroid hormone receptor responsible for polychlorinated biphenyl-mediated suppression of its action in vitro.

    Wataru Miyazaki, Toshiharu Iwasaki, Akira Takeshita, Chiharu Tohyama, Noriyuki Koibuchi

    Environmental health perspectives   116 ( 9 )   1231 - 1236   2008.9

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  • Augmentation of estrogen receptor-mediated transcription by steroid and xenobiotic receptor.

    Nana Rokutanda, Toshiharu Iwasaki, Hiroki Odawara, Rin Nagaoka, Wataru Miyazaki, Akira Takeshita, Yukio Koibuchi, Jun Horiguchi, Noriaki Shimokawa, Yuichi Iino, Yasuo Morishita, Noriyuki Koibuchi

    Endocrine   33 ( 3 )   305 - 316   2008.6

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  • The role of thyroid hormone in developing cerebellum.

    Noriyuki Koibuchi, Chun-Hong Qiu, Wataru Miyazaki, Toshiharu Iwasaki, Noriaki Shimokawa

    Cerebellum (London, England)   7 ( 3 )   499 - 500   2008

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  • Low dose hydroxylated PCB induces c-Jun expression in PC12 cells.

    Noriaki Shimokawa, Wataru Miyazaki, Toshiharu Iwasaki, Noriyuki Koibuchi

    Neurotoxicology   27 ( 2 )   176 - 183   2006.3

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  • The interaction of TRbeta1-N terminus with steroid receptor coactivator-1 (SRC-1) serves a full transcriptional activation function of SRC-1.

    Toshiharu Iwasaki, Akira Takeshita, Wataru Miyazaki, William W Chin, Noriyuki Koibuchi

    Endocrinology   147 ( 3 )   1452 - 1457   2006.3

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  • Polychlorinated biphenyls suppress thyroid hormone receptor-mediated transcription through a novel mechanism.

    Wataru Miyazaki, Toshiharu Iwasaki, Akira Takeshita, Yoichiro Kuroda, Noriyuki Koibuchi

    The Journal of biological chemistry   279 ( 18 )   18195 - 18202   2004.4

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  • Polychlorinated biphenyls suppress thyroid hormone-induced transactivation.

    Toshiharu Iwasaki, Wataru Miyazaki, Akira Takeshita, Yoichiro Kuroda, Noriyuki Koibuchi

    Biochemical and biophysical research communications   299 ( 3 )   384 - 388   2002.12

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Books

  • ガイトン生理学第13版

    宮崎航、鯉淵典之( Role: Joint translator)

    エルゼビア・ジャパン社  2018.3 

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    Language:Japanese Book type:Scholarly book

  • Possible mechanism of PCB actions, which are not Mediated by AhR.

    Miyazaki W, Londono MB, Iwasaki T, Shimokawa N, Koibuchi N.( Role: Joint author)

    Persistent Organic Pollutants (POPs) Research in Asia.  2007.9 

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Review Papers

  • 甲状腺ホルモンの中枢作用に及ぼす内分泌かく乱物質の影響

    鯉淵典之、岩崎俊晴、宮崎航、岡田淳一、下川哲昭、竹下彰、黒田洋一郎

    ホルモンと臨床   2005

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Kind of work:Joint Work  

  • 甲状腺ホルモンによる遺伝子発現とPCB類によるかく乱

    鯉淵典之、岩崎俊晴、宮崎航、Yousefi Behnaz、梅津元昭、黒田洋一郎

    Brain Medical   2004

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Kind of work:Joint Work