Updated on 2025/03/27

写真a

 
FUJISHIMA Yohei
 
Affiliation
Institute of Radiation Emergency Medicine

Degree

  • Doctor of Health Sciences

  • Master of Health Sciences

Education

  • Hirosaki University   Graduate School of Health Sciences   Health Sciences   Doctor's Course   Completed

    2016.04 2019.03

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    Country: Japan

  • Hirosaki University   Graduate School of Health Sciences   Health Sciences   Master's Course   Completed

    2014.04 2016.03

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    Country: Japan

  • Hirosaki University   Faculty of Medicine   Department of Medical Technology, School of Health Sciences   Graduated

    2010.04 2014.03

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    Country: Japan

Campus Career

  • Hirosaki University   Institute of Radiation Emergency Medicine   Assistant Professor  

    2023.09 Now

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  • Hirosaki University   Institute of Radiation Emergency Medicine   Assistant Professor  

    2021.01 202108

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Research History

  • Hirosaki University   Department of Risk Analysis and Biodosimetry, Institute of Radiation Emergency Medicine   Assistant Professor

    2023.09 Now

  • Hirosaki University   Department of Risk Analysis and Biodosimetry, Institute of Radiation Emergency Medicine   Assistant Professor

    2021.01 2021.08

  • Tohoku University   Department of Radiation Biology, School of Medicine   Assistant Professor

    2019.04 2020.12

Research Areas

  • Life Science / Radiological sciences

Professional Memberships

  • International Association of Biological and EPR Radiation Dosimetry (IABERD)

  • The Japanese Radiation Research Society

Papers

  • Potential radiosensitive germline biomarkers in the testes of wild mice after the Fukushima accident

    Tokita S, Nakayama R, Fujishima Y, Goh VST, Anderson D, Uemura I, Ikema H, Shibata J, Kinoshita Y, Shimizu Y, Shinoda H, Goto J, Palmerini MG, Hatha AM, Satoh T, Nakata A, Fukumoto M, Miura T, Yamashiro H

    FEBS open bio   15 ( 2 )   296 - 310   2025.2

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    PubMed

  • An efficient and simple method for enriching metaphase cells for dicentric chromosome assay

    Nakayama R, Tran TM, Anderson D, Takebayashi K, Goh VST, Fujishima Y, Miura T

    Radiation Protection Dosimetry   200 ( 16-18 )   1641 - 1646   2024.11

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    PubMed

  • Optimizing chemical-induced premature chromosome condensation assay for rapid estimation of high-radiation doses

    Nakayama R, Anderson D, Goh VST, Fujishima Y, Yanagidate K, Ariyoshi K, Kasai K, Yoshida MA, Blakely WF, Miura T

    Radiation Protection Dosimetry   200 ( 5 )   448 - 458   2024.4

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    PubMed

  • Ultrastructural Analysis of Large Japanese Field Mouse (Apodemus speciosus) Testes Exposed to Low-Dose-Rate (LDR) Radiation after the Fukushima Nuclear Power Plant Accident

    Gatti M, Belli M, De Rubeis M, Tokita S, Ikema H, Yamashiro H, Fujishima Y, Anderson D, Goh VST, Shinoda H, Nakata A, Fukumoto M, Miura T, Nottola SA, Macchiarelli G, Palmerini MG

    Biology   13 ( 4 )   239   2024.4

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    PubMed

  • AMPK/FOXO3a pathway increases activity and/or expression of ATM, DNA-PKcs, Src, EGFR, PDK1, and SOD2 and induces radioresistance under nutrient starvation

    Urushihara Y, Hashimoto T, Fujishima Y, Hosoi Y

    International Journal of Molecular Sciences   24 ( 16 )   12828   2023.8

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    PubMed

  • Mitotic index maximization with no effect on radiation-induced dicentric chromosome frequency

    Takebayashi K, Echizenya K, Kameya Y, Nakajima D, Nakayama R, Fujishima Y, Goh VST, Abe Y, Kasai K, Anderson D, Blakely WF, Miura T

    International Journal of Radiation Biology   99 ( 5 )   750 - 759   2023.5

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    PubMed

  • Manual scoring with shortened 48 h cytokinesis-block micronucleus assay feasible for triage in the event of a mass-casualty radiation accident

    Goh VST, Fujishima Y, Nakayama R, Takebayashi K, Yoshida MA, Kasai K, Ariyoshi K, Miura T

    Radiation Research   199 ( 4 )   385 - 395   2023.4

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    PubMed

  • Exosome-like vesicles released from ob/ob mouse adipose tissue enhance cell survival of cells with radiation-induced genomic instability

    Ariyoshi K, Fujishima Y, Goh VST, Nakata A, Kasai K, Yoshida MA, Miura T

    Journal of Radiation Research   64 ( 2 )   352 - 357   2023.3

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  • Evaluation of sperm fertilization capacity of large Japanese field mice (Apodemus speciosus) exposed to chronic low dose-rate radiation after the Fukushima accident

    Nihei K, Tokita S, Yamashiro H, Goh VST, Nakayama R, Fujishima Y, Kino Y, Shimizu Y, Shinoda H, Ariyoshi K, Kasai K, Abe Y, Fukumoto M, Nakata A, Miura T

    Journal of Radiation Research and Applied Sciences   15 ( 3 )   186 - 190   2022.9

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  • Environmental radiation on large Japanese field mice in Fukushima reduced colony forming potential in hematopoietic progenitor cells without inducing genomic instability

    Ariyoshi K, Miura T, Kasai K, Goh VST, Fujishima Y, Nakata A, Takahashi A, Shimizu Y, Shinoda H, Yamashiro H, Seymour C, Mothersill C, Yoshida MA

    International Journal of Radiation Biology   98 ( 6 )   1159 - 1167   2022.6

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  • Assessment of chromosome aberrations in large Japanese field mice (Apodemus speciosus) in Namie Town, Fukushima

    Fujishima Y, Nakata A, Ujiie R, Kasai K, Ariyoshi K, Goh VST, Suzuki K, Tazoe H, Yamada M, Yoshida MA, Miura T

    International Journal of Radiation Biology   98 ( 6 )   1159 - 1167   2022.6

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  • Changes in ovarian morphology and hormone concentrations associated with reproductive seasonality in wild large Japanese field mice (Apodemus speciosus)

    Komatsu K, Murata K, Iwasaki T, Tokita S, Yonekura S, Sugimura S, Fujishima Y, Nakata A, Miura T, Yamashiro H

    Animal Reproduction   18 ( 4 )   e20210067   2022.1

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    PubMed

  • AMPK increases expression of ATM through transcriptional factor Sp1 and induces radioresistance under severe hypoxia in glioblastoma cell lines

    Hashimoto T, Urushihara Y, Murata Y, Fujishima Y, Hosoi Y

    Biochemical and Biophysical Research Communications   590   82 - 88   2022.1

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    PubMed

  • Cytokinesis-block micronucleus assay performed in 0 and 2 Gy irradiated whole blood and isolated PBMCs in a six-well transwell co-culture system

    Goh VST, Takebayashi K, Nakayama R, Fujishima Y, Yoshida MA, Kasai K, Ariyoshi K, Miura T

    International Journal of Radiation Biology   97 ( 12 )   1631 - 1640   2021.12

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    PubMed

  • Evaluation of global DNA methylation and gene expression of Izumo1 and Izumo1r in gonads after high- and low-dose radiation in neonatal mice

    Nakata A, Sato K, Fujishima Y, Goh VST, Nakayama K, Ariyoshi K, Tsuruoka C, Shang Y, Iizuka D, Kakinuma S, Yamashiro H, Miura T

    Biology   10 ( 12 )   1270   2021.12

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    PubMed

  • Morphological reproductive characteristics of testes and fertilization capacity of cryopreserved sperm after the Fukushima accident in raccoon (Procyon lotor)

    Komatsu K, Iwasaki T, Murata K, Yamashiro H, Goh VST, Nakayama R, Fujishima Y, Ono T, Kino Y, Simizu Y, Takahashi A, Shinoda H, Ariyoshi K, Kasai K, Suzuki M, Palmerini MG, Belli M, Macchiarelli G, Oka T, Fukumoto M, Yoshida MA, Nakata A, Miura T

    Reproduction in Domestic Animals   56 ( 3 )   484 - 497   2021.3

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  • Contribution of light and electron microscopy in the identification of morphological alterations in large Japanese field mouse (Apodemus speciosus) testes exposed to low-dose-rate radiations

    Gatti M, Palmerini MG, Belli M, Nottola SA, Fujishima Y, Yamashiro H, Nakata A, Miura T, Macchiarelli G

    Microscopie   31 ( 2 )   56 - 63   2021.3

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  • Transition of radioactive cesium deposition in reproductive organs of free-roaming cats in Namie Town, Fukushima.

    Fujishima Y, Kino Y, Ono T, Goh VST, Nakata A, Ariyoshi K, Kasai K, Toyoda T, Akama T, Tazoe H, Yamada M, Yoshida MA, Miura T

    International Journal of Environmental Research and Public Health   18 ( 4 )   1772   2021.2

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  • Improved harvest and fixation methodology for isolated human peripheral blood mononuclear cells in cytokinesis-block micronucleus assay

    Goh VST, Nakayama R, Blakely WF, Abe Y, Chua CEL, Chew ZH, Nakata A, Fujishima Y, Yoshida MA, Kasai K, Ariyoshi K, Miura T

    International Journal of Radiation Biology   97 ( 2 )   194 - 207   2021.2

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  • Extracellular vesicles released from irradiated neonatal mouse cheek tissue increased cell survival after radiation

    Ariyoshi K, Hiroyama Y, Fujiwara N, Miura T, Kasai K, Nakata A, Fujishima Y, Goh VST, Yoshida MA

    Journal of Radiation Research   62 ( 1 )   73 - 78   2021.1

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  • Seasonal changes in the spermatogenesis of the large Japanese field mice (Apodemus speciosus) controlled by proliferation and apoptosis of germ cells

    Ito J, Meguro K, Komatsu K, Ohdaira T, Shoji R, Yamada T, Sugimura S, Fujishima Y, Nakata A, Fukumoto M, Miura T, Yamashiro H

    Animal Reproduction Science   214   106288   2020.3

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  • Analysis of radioactive elements in testes of large Japanese field mice using an electron probe micro-analyser after the Fukushima accident

    Ohdaira T, Meguro K, Komatsu K, Syoji R, Fujishima Y, Goh VST, Kasai K, Ariyoshi K, Nakata A, Urushihara Y, Koarai K, Kino Y, Sekine T, Suzuki M, Takahashi A, Shimizu Y, Shinoda H, Yoshida MA, Fukumoto M, Yamashiro H, Miura T

    Ionizing and Non-ionizing Radiation (London: IntechOpen)   1 - 9   2020.1

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  • DNA-PKcs is activated under nutrient starvation and activates Akt, MST1, FoxO3a, and NDR1

    Shiga S, Murata Y, Hashimoto T, Urushihara Y, Fujishima Y, Kudo K, Sonohara Y, Kurusu M, Takeda K, Jingu K, Hosoi Y

    Biochemical and Biophysical Research Communications   521 ( 3 )   668 - 673   2020.1

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  • Construction of fluorescence in situ hybridization (FISH) translocation dose-response calibration curve with multiple donor data sets using R, based on ISO 20046:2019 recommendations

    Goh VST, Fujishima Y, Abe Y, Sakai A, Yoshida MA, Ariyoshi K, Kasai K, Wilkins RC, Blakely WF, Miura T

    International Journal of Radiation Biology   95 ( 12 )   1668 - 1684   2019.12

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  • Chromosome studies in peripheral lymphocytes obtained from the orthopaedic surgeons received partial exposure

    Miura T, Echigoya N, Goh VST, Ito K, Mikami S, Yanagidate K, Fujishima Y, Ariyoshi K, Kasai K, Nakata A, Ishibashi Y, Yoshida MA

    The Journal of the Japanese Orthopaedic Association   93 ( 10 )   774 - 779   2019.10

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Precision of scoring radiation-induced chromosomal aberrations and micronuclei by unexperienced scorers

    Gałecki M, Tartas A, Szymanek A, Sims E, Lundholm L, Sollazzo A, Cheng L, Fujishima Y, Yoshida MA, Żygierewicz J, Wojcik A, Brzozowska-Wardecka B

    International Journal of Radiation Biology   95 ( 9 )   1251 - 1258   2019.9

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  • Radiation-induced bystander effect is mediated by mitochondrial DNA in exosome-like vesicles

    Ariyoshi K, Miura T, Kasai K, Fujishima Y, Nakata A, Yoshida MA

    Scientific Reports   9 ( 1 )   9103   2019.6

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  • Influence of anticoagulants and storage temperatures on blood counts and mitotic index of blood samples collected for cytogenetic biodosimetry

    Fujishima Y, Kanahama S, Hagino S, Natsubori S, Saito H, Azumaya A, Ariyoshi K, Nakata A, Kasai K, Yamada K, Mariya Y, Yoshida MA, Miura T

    International Journal of Radiation Biology   95 ( 2 )   186 - 192   2019.2

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  • Age dependence of radiation-induced genomic instability in mouse hematopoietic stem cells

    Ariyoshi K, Miura T, Kasai K, Akifumi N, Fujishima Y, Shinagawa M, Kadono K, Nishimura M, Kakinuma S, Yoshida MA

    Radiation Research   190 ( 6 )   623 - 633   2018.10

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  • Radiation-induced bystander effect in large Japanese field mouse (Apodemus speciosus) embryonic cells

    Ariyoshi K, Miura T, Kasai K, Akifumi N, Fujishima Y, Yoshida MA

    Radiation and Environmental Biophysics   57 ( 3 )   223 - 231   2018.8

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  • Possibility of inhibiting arthritis and joint destruction by SSEA-3 positive cells derived from synovial tissue in rheumatoid arthritis

    Kurose R, Sawai T, Oishi K, Liu X, Sasaki A, Kurose A, Kumagai N, Fujishima Y, Ishibashi Y

    Regenerative Therapy   7   82 - 88   2017.12

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  • Rapid isolation of murine primary hepatocytes for chromosomal analysis

    Ariyoshi K, Fujishima Y, Miura T, Shang Y, Kakinuma S, Yoshiya S, Kasai K, Nakata A, Tachibana A, Yoshida MA

    In Vitro Cellular & Developmental Biology - Animal   53 ( 5 )   474 - 478   2017.5

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  • Analysis of the Effect of Chronic and Low-Dose Radiation Exposure on Spermatogenic Cells of Male Large Japanese Field Mice (Apodemus speciosus) after the Fukushima Daiichi Nuclear Power Plant Accident

    Takino S, Yamashiro H, Sugano Y, Fujishima Y, Nakata A, Kasai K, Hayashi G, Urushihara Y, Suzuki M, Shinoda H, Miura T, Fukumoto M

    Radiation Research   187 ( 2 )   161 - 168   2017.2

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  • 細胞遺伝学的被ばく線量評価における抗凝固剤および血液保存温度の影響

    金浜朱希,藤嶋洋平,川森詩織,成田房恵,萩野繁樹,有吉健太郎,吉田光明,山田恭吾,真里谷靖,三浦富智

    青臨技会誌   41   24 - 27   2016.12

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  • Induction of genomic instability and activation of autophagy in artificial human aneuploid cells

    Ariyoshi K, Miura T, Kasai K, Fujishima Y, Oshimura M, and Yoshida MA

    Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis   790   19 - 30   2016.8

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Review Papers

  • Cytogenetic biodosimetry in radiation emergency medicine: 6. Cytokinesis-block micronucleus assay and its role in biodosimetry

    Goh VST, Anderson D, Fujishima Y, Nakayama T, Tran TM, Takebayashi K, Abe Y, Kasai K, Ariyoshi K, Nakata A, Yoshida MA, Miura T

    Radiation Environment and Medicine   14 ( 1 )   17 - 36   2025.3

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    Language:English   Publishing type:Article, review, commentary, editorial, etc. (bulletin of university, research institution)   Kind of work:Joint Work  

  • Meeting report on the EPRBioDose 2024, Hirosaki

    Fujishima Y, Anderson D, Abe Y, Lobna A, Oka T, Tani A, Chutima K, Toyoda S, Hamasaki K, Hirota S, Yasuda H, Yamaguchi I, Yamanaka C, Miura T

    Journal of Japanese Association for Radiation Accident/Disaster Medicine   7 ( 1 )   21 - 26   2024.12

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    Language:Japanese   Publishing type:Meeting report   Kind of work:Joint Work  

  • Cytogenetic biodosimetry in radiation emergency medicine: 5. The dicentric chromosome and its role in biodosimetry

    Anderson D, Abe Y, Goh VST, Nakayama R, Takebayashi K, Tran TM, Fujishima Y, Nakata A, Ariyoshi K, Kasai K, Yoshida MA, Miura T

    Radiation Environment and Medicine   12 ( 2 )   121 - 139   2023.8

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  • Cytogenetic biodosimetry in radiation emergency medicine: 3. The basics of chromosomes for biodosimetry.

    Nakata A, Ariyoshi K, Abe Y, Fujishima Y, Goh VST, Nakayama R, Takebayashi K, Tran TM, Kasai K, Yoshida MA, Miura T

    Radiation Environment and Medicine   11 ( 2 )   82 - 90   2022.8

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  • Cytogenetic biodosimetry in radiation emergency medicine: 4. Overview of cytogenetic biodosimetry.

    Nakayama R, Abe Y, Goh VST, Takebayashi K, Tran TM, Fujishima Y, Nakata A, Ariyoshi K, Kasai K, Anderson D, Hanada H, Yoshida MA, Ito K, Miura T

    Radiation Environment and Medicine   11 ( 2 )   91 - 103   2022.8

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  • Cytogenetic biodosimetry in radiation emergency medicine: 1. Blood collection and its management.

    Fujishima Y, Abe Y, Goh VST, Nakayama R, Takebayashi K, Nakata A, Ariyoshi K, Tran T, M, Kasai K, Hanada H, Yoshida MA, Ito K, Miura T

    Radiation Environment and Medicine   11 ( 1 )   25 - 33   2022.2

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  • Cytogenetic biodosimetry in radiation emergency medicine: 2. Biosafety and chemical safety in biodosimetry laboratory.

    Kasai K, Abe Y, Goh VST, Tran T, M, Fujishima Y, Nakayama R, Takebayashi K, Nakata A, Ariyoshi K, Hanada H, Yoshida MA, Ito K, Miura T

    Radiation Environment and Medicine   11 ( 1 )   34 - 39   2022.2

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  • Radiation emergency medical preparedness for cytogenetic biodosimetry in Hirosaki University, Japan.

    Miura T, Goh VST, Fujishima Y, Takebayashi K, Nakayama R, Kasai K, Ariyoshi K, Tsujiguchi T, Yoshida MA

    AIP Conference Proceedings   2381   020041   2021.11

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  • Human resource development for cytogenetic biodosimetry at Hirosaki University.

    Miura T, Kasai K, Abe Y, Fujishima Y, Goh VST, Nakayama R, Takebayashi K, Sasaki N, Ariyoshi K, Nakata A, Tsujiguchi T, Ito K, Hanada H, Yoshida MA

    Radiation Environment and Medicine   10 ( 2 )   102 - 107   2021.8

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  • Support activities in Namie Town, Fukushima undertaken by Hirosaki University

    Tokonami S, Miura T, Akata N, Tazoe H, Hosoda M, Chutima K, Kudo H, Ogura K, Fujishima Y, Tamakuma Y, Shimizu M, Kikuchi K, Kashiwakura I

    Annals of the ICRP   50 ( 1_suppl )   102 - 108   2021.7

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  • International Activities on Radiation Emergency Medical Personnel Training : Reports of Japan-Korea Joint Radiation Emergency Medicine Winter Training 2019

    Tsujiguchi T, Cha S, Lee J, Cho M, Fujishima Y, Tanaka K, Yamaguchi M, Itaki C

    Radiation Environment and Medicine   9 ( 1 )   35 - 40   2020.2

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  • Meeting report on "The 4th Educational Symposium on Radiation and Health (ESRAH) by Young Scientists in 2017"

    Saga R, Tsujiguchi T, Yamaguchi M, Fukushi Y, Fujishima Y, Matsuya Y, Oikawa J, Terashima M, Date H, Nakamura T, Hosokawa Y

    Radiation Environment and Medicine   7 ( 2 )   121 - 124   2018.9

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  • Educational activity for the radiation emergency system in the northern part of Japan: Meeting report on "The 3rd Educational Symposium on Radiation and Health (ESRAH) by Young Scientists in 2016"

    Matsuya Y, Kimura T, Yamada R, Mori T, Tsujiguchi T, Yamaguchi M, Saga R, Fujishima Y, Date H

    Radiation Research   187 ( 6 )   641 - 646   2017.6

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  • Report on the 2nd Educational Symposium on RADIATION AND HEALTH by Young Scientists (ESRAH2015)

    Tsujiguchi T, Yamaguchi M, Nanashima N, Chiba M, Terashima S, Fujishima Y, Matsuya Y, Kwon J, Nakamura T

    Radiation Environment and Medicine   5 ( 1 )   65 - 71   2016.1

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  • The Report of the 2nd Educational Symposium on Radiation and Health by Young Scientists (ESRAH2015)

    Tsujiguchi T, Yamaguchi M, Nanashima N, Chiba M, Terashima S, Fujishima Y, Matsuya Y, Kwon J, Nakamura T

    Japanese Journal of Radiological Technology   71 ( 11 )   1132 - 1137   2015.11

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Awards

  • Young Scientist Poster Prize (EPR BioDose 2018)

    2018.06

  • Kato Memorial Bioscience Foundation

    2018.03

Social Activities

  • 令和5年度高度専門染色体分析研修

    2023.12.08