研究者詳細 - 藤嶋　洋平

論文 - 藤嶋　洋平

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Effective centrifugation techniques for improving the frequency of metaphase spreads in lymphocytopenic patients

Yoon HJ, Ko HY, Yang SS, Kwon SW, Cho M, Lee JK, Miura T, Fujishima Y, Anderson D, Lee YH

International Journal of Radiation Biology 102 ( 7 ) 813 - 820 2026年07月

Feasibility study on automated cytokinesis-block micronucleus assay analysis in cytogenetic biodosimetry using YOLOv5 object detection

Fujishima Y, Goh VST, Anderson D, Miura T

International Journal of Radiation Biology 102 ( 7 ) 821 - 830 2026年07月

Image selection is critical in the dicentric chromosome assay in cytogenetic biodosimetry

Okimoto A, Anderson D, Fujishima Y, Kadowaki Y, Suzuki H, Miura T

International Journal of Radiation Biology 102 ( 7 ) 806 - 812 2026年07月

Radiation research at Hirosaki University after the Fukushima accident: Contributions to public health, education, and community resilience

Hosoda M., Anderson D, Yamada R, Fujishima Y, Tanaka K, Kudo H, Omori Y, Kuranrod C, Tazoe H, Akata N, Itaki C, Miura T, Kashiwakura I, Tokonami S

Radiation Medicine and Protection 7 ( 3 ) 124 - 136 2026年06月

Cytotoxic and genotoxic responses of human lung adenocarcinoma cells to sequential exposure to household dust extract and indoor radon

Autsavapromporn N., Duangya A., Kawichai S., Bootdee S., Sillapapiromsuk S., Kranrod C., Anderson D., Fujishima Y., Miura T., Tokonami S.

Environments 13 ( 5 ) 280 2026年05月

Animal-origin-free culture improves mitotic response for chromosome aberration analysis of human peripheral blood

Fujishima Y, Anderson D, Kamakura S, Saito R, Tsushima Y, Okimoto A, Goh VST, Miura T

PNAS Nexus 5 ( 4 ) pgag120 2026年04月

MaksChroms: An open-source CNN-based tool for dose prediction based on dicentric chromosome assay

Głowacki M, Bucher M, Endesfelder D, Szoła M, Tartas A, Fujishima Y, Oestreicher U, Kowalska M, Kotowski P, Borkowski J, Pszczółkowska-Kępa B, Ginter J, Wojcik A, Brzozowska B

Radiation Physics and Chemistry 239 113329 2026年02月

Occupational radiation exposure indicated by increased chromosomal damage in lymphocytes of orthopaedic surgeons in Japan

Anderson D, Goh VST, Fujishima Y, Nakayama R, Echigoya N, Ishibashi Y, Miura T

Journal of Radiation Research 67 ( 1 ) 68 - 77 2026年01月

Estimated radiation doses to potential adoptive-owners of dogs and cats rescued from Chernobyl and Fukushima

Harshman AM, Fujishima Y, Anderson D

Journal of Environmental Radioactivity 290 107786 2025年11月

Nuclear factor erythroid 2-related factor 2 (NRF2) as a biomarker for radiation dosimetry and health risk assessment: A review

Moloudi K, Sangsuwan T, Monzen S, Fujishima Y, Anderson D, Frey B, Miura T, Azariasl S, Yasuda H, Haghdoost S

Antioxidants 14 ( 12 ) 1393 - 1393 2025年11月

Potential radiosensitive germline biomarkers in the testes of wild mice after the Fukushima accident

Tokita S, Nakayama R, Fujishima Y, Goh VST, Anderson D, Uemura I, Ikema H, Shibata J, Kinoshita Y, Shimizu Y, Shinoda H, Goto J, Palmerini MG, Hatha AM, Satoh T, Nakata A, Fukumoto M, Miura T, Yamashiro H

FEBS open bio 15 ( 2 ) 296 - 310 2025年02月

An efficient and simple method for enriching metaphase cells for dicentric chromosome assay

Nakayama R, Tran TM, Anderson D, Takebayashi K, Goh VST, Fujishima Y, Miura T

Radiation Protection Dosimetry 200 ( 16-18 ) 1641 - 1646 2024年11月

Ultrastructural Analysis of Large Japanese Field Mouse (Apodemus speciosus) Testes Exposed to Low-Dose-Rate (LDR) Radiation after the Fukushima Nuclear Power Plant Accident

Gatti M, Belli M, De Rubeis M, Tokita S, Ikema H, Yamashiro H, Fujishima Y, Anderson D, Goh VST, Shinoda H, Nakata A, Fukumoto M, Miura T, Nottola SA, Macchiarelli G, Palmerini MG

Biology 13 ( 4 ) 239 2024年04月

Optimizing chemical-induced premature chromosome condensation assay for rapid estimation of high-radiation doses

Nakayama R, Anderson D, Goh VST, Fujishima Y, Yanagidate K, Ariyoshi K, Kasai K, Yoshida MA, Blakely WF, Miura T

Radiation Protection Dosimetry 200 ( 5 ) 448 - 458 2024年04月

AMPK/FOXO3a pathway increases activity and/or expression of ATM, DNA-PKcs, Src, EGFR, PDK1, and SOD2 and induces radioresistance under nutrient starvation

Urushihara Y, Hashimoto T, Fujishima Y, Hosoi Y

International Journal of Molecular Sciences 24 ( 16 ) 12828 2023年08月

Mitotic index maximization with no effect on radiation-induced dicentric chromosome frequency

Takebayashi K, Echizenya K, Kameya Y, Nakajima D, Nakayama R, Fujishima Y, Goh VST, Abe Y, Kasai K, Anderson D, Blakely WF, Miura T

International Journal of Radiation Biology 99 ( 5 ) 750 - 759 2023年05月

Manual scoring with shortened 48 h cytokinesis-block micronucleus assay feasible for triage in the event of a mass-casualty radiation accident

Goh VST, Fujishima Y, Nakayama R, Takebayashi K, Yoshida MA, Kasai K, Ariyoshi K, Miura T

Radiation Research 199 ( 4 ) 385 - 395 2023年04月

Exosome-like vesicles released from ob/ob mouse adipose tissue enhance cell survival of cells with radiation-induced genomic instability

Ariyoshi K, Fujishima Y, Goh VST, Nakata A, Kasai K, Yoshida MA, Miura T

Journal of Radiation Research 64 ( 2 ) 352 - 357 2023年03月

Evaluation of sperm fertilization capacity of large Japanese field mice (Apodemus speciosus) exposed to chronic low dose-rate radiation after the Fukushima accident

Nihei K, Tokita S, Yamashiro H, Goh VST, Nakayama R, Fujishima Y, Kino Y, Shimizu Y, Shinoda H, Ariyoshi K, Kasai K, Abe Y, Fukumoto M, Nakata A, Miura T

Journal of Radiation Research and Applied Sciences 15 ( 3 ) 186 - 190 2022年09月

Environmental radiation on large Japanese field mice in Fukushima reduced colony forming potential in hematopoietic progenitor cells without inducing genomic instability

Ariyoshi K, Miura T, Kasai K, Goh VST, Fujishima Y, Nakata A, Takahashi A, Shimizu Y, Shinoda H, Yamashiro H, Seymour C, Mothersill C, Yoshida MA

International Journal of Radiation Biology 98 ( 6 ) 1159 - 1167 2022年06月

Assessment of chromosome aberrations in large Japanese field mice (Apodemus speciosus) in Namie Town, Fukushima

Fujishima Y, Nakata A, Ujiie R, Kasai K, Ariyoshi K, Goh VST, Suzuki K, Tazoe H, Yamada M, Yoshida MA, Miura T

International Journal of Radiation Biology 98 ( 6 ) 1159 - 1167 2022年06月

Changes in ovarian morphology and hormone concentrations associated with reproductive seasonality in wild large Japanese field mice (Apodemus speciosus)

Komatsu K, Murata K, Iwasaki T, Tokita S, Yonekura S, Sugimura S, Fujishima Y, Nakata A, Miura T, Yamashiro H

Animal Reproduction 18 ( 4 ) e20210067 2022年01月

AMPK increases expression of ATM through transcriptional factor Sp1 and induces radioresistance under severe hypoxia in glioblastoma cell lines

Hashimoto T, Urushihara Y, Murata Y, Fujishima Y, Hosoi Y

Biochemical and Biophysical Research Communications 590 82 - 88 2022年01月

Cytokinesis-block micronucleus assay performed in 0 and 2 Gy irradiated whole blood and isolated PBMCs in a six-well transwell co-culture system

Goh VST, Takebayashi K, Nakayama R, Fujishima Y, Yoshida MA, Kasai K, Ariyoshi K, Miura T

International Journal of Radiation Biology 97 ( 12 ) 1631 - 1640 2021年12月

Evaluation of global DNA methylation and gene expression of Izumo1 and Izumo1r in gonads after high- and low-dose radiation in neonatal mice

Nakata A, Sato K, Fujishima Y, Goh VST, Nakayama K, Ariyoshi K, Tsuruoka C, Shang Y, Iizuka D, Kakinuma S, Yamashiro H, Miura T

Biology 10 ( 12 ) 1270 2021年12月

Morphological reproductive characteristics of testes and fertilization capacity of cryopreserved sperm after the Fukushima accident in raccoon (Procyon lotor)

Komatsu K, Iwasaki T, Murata K, Yamashiro H, Goh VST, Nakayama R, Fujishima Y, Ono T, Kino Y, Simizu Y, Takahashi A, Shinoda H, Ariyoshi K, Kasai K, Suzuki M, Palmerini MG, Belli M, Macchiarelli G, Oka T, Fukumoto M, Yoshida MA, Nakata A, Miura T

Reproduction in Domestic Animals 56 ( 3 ) 484 - 497 2021年03月

Contribution of light and electron microscopy in the identification of morphological alterations in large Japanese field mouse (Apodemus speciosus) testes exposed to low-dose-rate radiations

Gatti M, Palmerini MG, Belli M, Nottola SA, Fujishima Y, Yamashiro H, Nakata A, Miura T, Macchiarelli G

Microscopie 31 ( 2 ) 56 - 63 2021年03月

Transition of radioactive cesium deposition in reproductive organs of free-roaming cats in Namie Town, Fukushima.

Fujishima Y, Kino Y, Ono T, Goh VST, Nakata A, Ariyoshi K, Kasai K, Toyoda T, Akama T, Tazoe H, Yamada M, Yoshida MA, Miura T

International Journal of Environmental Research and Public Health 18 ( 4 ) 1772 2021年02月

Improved harvest and fixation methodology for isolated human peripheral blood mononuclear cells in cytokinesis-block micronucleus assay

Goh VST, Nakayama R, Blakely WF, Abe Y, Chua CEL, Chew ZH, Nakata A, Fujishima Y, Yoshida MA, Kasai K, Ariyoshi K, Miura T

International Journal of Radiation Biology 97 ( 2 ) 194 - 207 2021年02月

Extracellular vesicles released from irradiated neonatal mouse cheek tissue increased cell survival after radiation

Ariyoshi K, Hiroyama Y, Fujiwara N, Miura T, Kasai K, Nakata A, Fujishima Y, Goh VST, Yoshida MA

Journal of Radiation Research 62 ( 1 ) 73 - 78 2021年01月

Seasonal changes in the spermatogenesis of the large Japanese field mice (Apodemus speciosus) controlled by proliferation and apoptosis of germ cells

Ito J, Meguro K, Komatsu K, Ohdaira T, Shoji R, Yamada T, Sugimura S, Fujishima Y, Nakata A, Fukumoto M, Miura T, Yamashiro H

Animal Reproduction Science 214 106288 2020年03月

Analysis of radioactive elements in testes of large Japanese field mice using an electron probe micro-analyser after the Fukushima accident

Ohdaira T, Meguro K, Komatsu K, Syoji R, Fujishima Y, Goh VST, Kasai K, Ariyoshi K, Nakata A, Urushihara Y, Koarai K, Kino Y, Sekine T, Suzuki M, Takahashi A, Shimizu Y, Shinoda H, Yoshida MA, Fukumoto M, Yamashiro H, Miura T

Ionizing and Non-ionizing Radiation (London: IntechOpen) 1 - 9 2020年01月

DNA-PKcs is activated under nutrient starvation and activates Akt, MST1, FoxO3a, and NDR1

Shiga S, Murata Y, Hashimoto T, Urushihara Y, Fujishima Y, Kudo K, Sonohara Y, Kurusu M, Takeda K, Jingu K, Hosoi Y

Biochemical and Biophysical Research Communications 521 ( 3 ) 668 - 673 2020年01月

Construction of fluorescence in situ hybridization (FISH) translocation dose-response calibration curve with multiple donor data sets using R, based on ISO 20046:2019 recommendations

Goh VST, Fujishima Y, Abe Y, Sakai A, Yoshida MA, Ariyoshi K, Kasai K, Wilkins RC, Blakely WF, Miura T

International Journal of Radiation Biology 95 ( 12 ) 1668 - 1684 2019年12月

超局所慢性被曝を受けた整形外科医の末梢血リンパ球における染色体異常解析 (シンポジウム整形外科医の医療被曝の現状と対策)

三浦富智，越後谷直樹，Valerie Swee Ting Goh，伊東杏，三上紗季，柳舘快利，藤嶋洋平，有吉健太郎，葛西宏介，中田章史，石橋恭之，吉田光明

日本整形外科学会雑誌 93 ( 10 ) 774 - 779 2019年10月

Precision of scoring radiation-induced chromosomal aberrations and micronuclei by unexperienced scorers

Gałecki M, Tartas A, Szymanek A, Sims E, Lundholm L, Sollazzo A, Cheng L, Fujishima Y, Yoshida MA, Żygierewicz J, Wojcik A, Brzozowska-Wardecka B

International Journal of Radiation Biology 95 ( 9 ) 1251 - 1258 2019年09月

Radiation-induced bystander effect is mediated by mitochondrial DNA in exosome-like vesicles

Ariyoshi K, Miura T, Kasai K, Fujishima Y, Nakata A, Yoshida MA

Scientific Reports 9 ( 1 ) 9103 2019年06月

Influence of anticoagulants and storage temperatures on blood counts and mitotic index of blood samples collected for cytogenetic biodosimetry

Fujishima Y, Kanahama S, Hagino S, Natsubori S, Saito H, Azumaya A, Ariyoshi K, Nakata A, Kasai K, Yamada K, Mariya Y, Yoshida MA, Miura T

International Journal of Radiation Biology 95 ( 2 ) 186 - 192 2019年02月

Age dependence of radiation-induced genomic instability in mouse hematopoietic stem cells

Ariyoshi K, Miura T, Kasai K, Akifumi N, Fujishima Y, Shinagawa M, Kadono K, Nishimura M, Kakinuma S, Yoshida MA

Radiation Research 190 ( 6 ) 623 - 633 2018年10月

Radiation-induced bystander effect in large Japanese field mouse (Apodemus speciosus) embryonic cells

Ariyoshi K, Miura T, Kasai K, Akifumi N, Fujishima Y, Yoshida MA

Radiation and Environmental Biophysics 57 ( 3 ) 223 - 231 2018年08月

Possibility of inhibiting arthritis and joint destruction by SSEA-3 positive cells derived from synovial tissue in rheumatoid arthritis

Kurose R, Sawai T, Oishi K, Liu X, Sasaki A, Kurose A, Kumagai N, Fujishima Y, Ishibashi Y

Regenerative Therapy 7 82 - 88 2017年12月

Rapid isolation of murine primary hepatocytes for chromosomal analysis

Ariyoshi K, Fujishima Y, Miura T, Shang Y, Kakinuma S, Yoshiya S, Kasai K, Nakata A, Tachibana A, Yoshida MA

In Vitro Cellular & Developmental Biology - Animal 53 ( 5 ) 474 - 478 2017年05月

Analysis of the Effect of Chronic and Low-Dose Radiation Exposure on Spermatogenic Cells of Male Large Japanese Field Mice (Apodemus speciosus) after the Fukushima Daiichi Nuclear Power Plant Accident

Takino S, Yamashiro H, Sugano Y, Fujishima Y, Nakata A, Kasai K, Hayashi G, Urushihara Y, Suzuki M, Shinoda H, Miura T, Fukumoto M

Radiation Research 187 ( 2 ) 161 - 168 2017年02月

細胞遺伝学的被ばく線量評価における抗凝固剤および血液保存温度の影響

金浜朱希，藤嶋洋平，川森詩織，成田房恵，萩野繁樹，有吉健太郎，吉田光明，山田恭吾，真里谷靖，三浦富智

青臨技会誌 41 24 - 27 2016年12月

Induction of genomic instability and activation of autophagy in artificial human aneuploid cells

Ariyoshi K, Miura T, Kasai K, Fujishima Y, Oshimura M, and Yoshida MA

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis 790 19 - 30 2016年08月

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論文 - 藤嶋　洋平