Papers - MURAI Yasuhisa
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VEXAS syndrome with eosinophilia and pathologically mimicking histiocytosis: A case report
Yasuhisa Murai, Rina Watanabe, Tatsuya Tsurumoto, Hidekachi Kurotaki, Takuto Tachita, Noriko Takiyoshi, Takahiko Nagaki, Naruki Kurosaka, Ren Yanagida, Ryoichi Kikuchi, Kaori Takasugi, Yoshitaka Zaimoku, Kyoko Amenomori, Shinji Ota, Keisuke Hasui, Satoko Yamaguchi, Hiroto Hiraga, Hiroshi Kanazawa, Hirotake Sakuraba
Modern Rheumatology Case Reports 2025.11
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Schlafen 11 expression in human acute leukemia cells with gain-of-function mutations in the interferon-JAK signaling pathway
Yasuhisa Murai, Ukhyun Jo, Junko Murai, Shinsaku Fukuda, Naoko Takebe, Yves Pommier
iScience 24 ( 10 ) 103173 - 103173 2021.10
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SLFN11 Inactivation Induces Proteotoxic Stress and Sensitizes Cancer Cells to Ubiquitin Activating Enzyme Inhibitor TAK-243
Yasuhisa Murai, Ukhyun Jo, Junko Murai, Lisa M. Jenkins, Shar-Yin N. Huang, Sirisha Chakka, Lu Chen, Ken Cheng, Shinsaku Fukuda, Naoko Takebe, Yves Pommier
Cancer Research 81 ( 11 ) 3067 - 3078 2021.6
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A case of radiotherapy concurrent with S-1 for bleeding at the progressive gastric cancer treated by Ramucirumab and Paclitaxel
Yasuhisa MURAI , Shohei IGARASHI , Keisuke HASUI , Koji SHIMAYA , Norihiro HANABATA , Kosuke KANAZAWA , Hiroshi NUMAO , Masaki MUNAKATA
Medical Journal Aomori 61 ( 4 ) 149 - 154 2016.12
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Coexistence of plasmablastic lymphoma and adenocarcinoma in the stomach: a case report and literature review.
Takato Maeda, Takenori Takahata, Shintaro Goto, Takao Oyama, Satoru Nakagawa, Yasuhisa Murai, Ryuma Machida, Nao Ishidoya, Juichi Sakamoto, Hideki Iwamura, Hirotake Sakuraba
International cancer conference journal 14 ( 2 ) 155 - 162 2025.4
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Solitary Peutz-Jeghers polyp harboring a focus of high-grade dysplasia in the colon: a case report and literature review.
Takato Maeda, Tadashi Yoshizawa, Takao Oyama, Satoru Nakagawa, Yasuhisa Murai, Ryuma Machida, Nao Ishidoya, Juichi Sakamoto, Hideki Iwamura, Hirotake Sakuraba
Clinical journal of gastroenterology 18 ( 1 ) 89 - 94 2025.2
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Colorectal Post-polypectomy Bleeding in Outpatient versus Inpatient Treatment: Propensity Score Matching Analysis
Maeda Takato, Sakuraba Hirotake, Oyama Takao, Nakagawa Satoru, Ota Shinji, Murai Yasuhisa, Machida Ryuma, Ishidoya Nao, Kikuchi Hidezumi, Chinda Daisuke, Sakamoto Juichi, Iwamura Hideki
Journal of the Anus, Rectum and Colon 8 ( 3 ) 204 - 211 2024.7
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Author Correction: ATR inhibition augments the efficacy of lurbinectedin in small-cell lung cancer
Christopher W Schultz, Yang Zhang, Rajaa Elmeskini, Astrid Zimmermann, Haiqing Fu, Yasuhisa Murai, Darawalee Wangsa, Suresh Kumar, Nobuyuki Takahashi, Devon Atkinson, Liton Kumar Saha, Chien-Fei Lee, Brian Elenbaas, Parth Desai, Robin Sebastian, Ajit Kumar Sharma, Melissa Abel, Brett Schroeder, Manan Krishnamurthy, Laurel L Bassel, Rajesh Kumar, Nitin Roper, Mirit Aladjem, Frank T Zenke, Zoe Weaver Ohler, Yves Pommier, Anish Thomas
EMBO Molecular Medicine 16 ( 3 ) 664 - 664 2024.2
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A Logistic Regression Model for Predicting the Risk of Subsequent Surgery among Patients with Newly Diagnosed Crohn’s Disease Using a Brute Force Method
Kohei Ogasawara, Hiroto Hiraga, Yoshihiro Sasaki, Noriko Hiraga, Naoki Higuchi, Keisuke Hasui, Shinji Ota, Takato Maeda, Yasuhisa Murai, Tetsuya Tatsuta, Hidezumi Kikuchi, Daisuke Chinda, Tatsuya Mikami, Masashi Matsuzaka, Hirotake Sakuraba, Shinsaku Fukuda
Diagnostics 13 ( 23 ) 3587 - 3587 2023.12
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Schlafen 11 (SLFN11) Kills Cancer Cells Undergoing Unscheduled Re-replication
Junko Murai, Michele Ceribelli, Haiqing Fu, Christophe E. Redon, Ukhyun Jo, Yasuhisa Murai, Mirit I. Aladjem, Craig J. Thomas, Yves Pommier
Molecular Cancer Therapeutics 22 ( 8 ) 985 - 995 2023.5
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Vitamin A Promotes the Fusion of Autophagolysosomes and Prevents Excessive Inflammasome Activation in Dextran Sulfate Sodium-Induced Colitis
Hiroto Hiraga, Daisuke Chinda, Takato Maeda, Yasuhisa Murai, Kohei Ogasawara, Ryutaro Muramoto, Shinji Ota, Keisuke Hasui, Hirotake Sakuraba, Yoh Ishiguro, Shukuko Yoshida, Krisana Asano, Akio Nakane, Shinsaku Fukuda
International Journal of Molecular Sciences 24 ( 10 ) 8684 - 8684 2023.5
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Evaluation of Crohn’s Disease Small-Bowel Mucosal Healing Using Capsule Endoscopy and Usefulness of Leucine-Rich α2-Glycoprotein
Hiroto Hiraga, Daisuke Chinda, Keisuke Hasui, Yasuhisa Murai, Takato Maeda, Naoki Higuchi, Kohei Ogasawara, Sae Kudo, Yohei Sawada, Tetsuya Tatsuta, Hidezumi Kikuchi, Mami Ebina, Noriko Hiraga, Tatsuya Mikami, Hirotake Sakuraba, Shinsaku Fukuda
Diagnostics 13 ( 4 ) 626 - 626 2023.2
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Bacterial exposure risk to the endoscopist's face while performing endoscopy
Kentaro Hoshi, Hidezumi Kikuchi, Koji Narita, Yukari Fukutoku, Taka Asari, Kuniaki Miyazawa, Yasuhisa Murai, Yohei Sawada, Tetsuya Tatsuta, Keisuke Hasui, Hiroto Hiraga, Daisuke Chinda, Tatsuya Mikami, Phawinee Subsomwong, Krisana Asano, Akio Nakane, Shinsaku Fukuda, Hirotake Sakuraba
DEN Open 3 ( 1 ) e209 2023.1
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Tacrolimus Up-regulates Expression of TGFβ Receptor Type II via ERK, Providing Protection Against Intestinal Epithelial Injury.
Satake M, Sakuraba H, Hiraga H, Yoshida S, Akemoto Y, Ota S, Murai Y, Hasui K, Kawaguchi S, Kikuchi H, Fukuda S
In vivo (Athens, Greece) 36 ( 4 ) 1684 - 1693 2022.7
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Polygonum tinctorium leaves suppress sodium dextran sulfate-induced colitis through interleukin-10-related pathway
Taka Asari, Hidezumi Kikuchi, Shogo Kawaguchi, Hirotake Sakuraba, Shukuko Yoshida, Yui Akemoto, Takato Maeda, Ota Shinji, Yasuhisa Murai, Naoki Higuchi, Kentaro Hoshi, Yukari Fukutoku, Hiroto Hiraga, Kenroh Sasaki, Shinsaku Fukuda
Biochemistry and Biophysics Reports 30 101272 - 101272 2022.7
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Automated evaluation of colon capsule endoscopic severity of ulcerative colitis using ResNet50
Naoki Higuchi,Hiroto Hiraga,Yoshihiro Sasaki,Noriko Hiraga,Shohei Igarashi,Keisuke Hasui,Kohei Ogasawara,Takato Maeda,Yasuhisa Murai,Tetsuya Tatsuta,Hidezumi Kikuchi,Daisuke Chinda,Tatsuya Mikami,Masashi Matsuzaka,Hirotake Sakuraba,Shinsaku Fukuda
PLOS ONE 17 ( 6 ) e0269728 2022.6
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TOP1-DNA trapping by exatecan and combination therapy with ATR inhibitor
Ukhyun Jo, Yasuhisa Murai, Keli K. Agama, Yilun Sun, Liton Kumar Saha, Xi Yang, Yasuhiro Arakawa, Sophia Gayle, Kelli Jones, Vishwas Paralkar, Ranjini K. Sundaram, Jinny Van Doorn, Juan C. Vasquez, Ranjit S. Bindra, Woo Suk Choi, Yves Pommier
Molecular Cancer Therapeutics 21 ( 7 ) 1090 - 1102 2022.4
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Endoscopic and histopathologic features of Anti-PD-1-related collagenous colitis
Hidezumi Kikuchi, Hirotake Sakuraba, Yui Akemoto, Kazuhiro Hosoi, Yasuhisa Murai, Kentaro Hoshi, Yukari Fukutoku, Taka Asari, Yohei Sawada, Keisuke Hasui, Tetsuya Tatsuta, Hiroto Hiraga, Daisuke Chinda, Tatsuya Mikami, Shinsaku Fukuda
DEN Open 2 ( e92 ) 2022.1
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Replication-dependent cytotoxicity and Spartan-mediated repair of trapped PARP1–DNA complexes
Liton Kumar Saha, Yasuhisa Murai, Sourav Saha, Ukhyun Jo, Masataka Tsuda, Shunichi Takeda, Yves Pommier
Nucleic Acids Research 49 ( 18 ) 10493 - 10506 2021.9
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Precision Oncology with Drugs Targeting the Replication Stress, ATR, and Schlafen 11
Ukhyun Jo, Yasuhisa Murai, Naoko Takebe, Anish Thomas, Yves Pommier
Cancers 13 ( 18 ) 4601 - 4601 2021.9
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Novel and highly potent ATR inhibitor M4344 kills cancer cells with replication stress and enhances the chemotherapeutic activity of widely used DNA damaging agents
Ukhyun Jo, Ilya S Senatorov, Astrid Zimmermann, Liton Kumar Saha, Yasuhisa Murai, Se Hyun Kim, Vinodh N. Rajapakse, Fathi Elloumi, Nobuyuki Takahashi, Christopher W. Schultz, Anish Thomas, Frank T. Zenke, Yves Pommier
Molecular Cancer Therapeutics 20 ( 8 ) 1431 - 1441 2021.5
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SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors
Ukhyun Jo, Yasuhisa Murai, Sirisha Chakka, Lu Chen, Ken Cheng, Junko Murai, Liton Kumar Saha, Lisa M. Miller Jenkins, Yves Pommier
Proceedings of the National Academy of Sciences 118 ( 6 ) e2015654118 - e2015654118 2021.2
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Cyclosporine protects from intestinal epithelial injury by modulating butyrate uptake via upregulation of membrane monocarboxylate transporter 1 levels.
Shinji Ota, Hirotake Sakuraba, Hiroto Hiraga, Shukuko Yoshida, Miwa Satake, Yui Akemoto, Nahoko Tanaka, Rina Watanabe, Maeda Takato, Yasuhisa Murai, Kayo Ueno, Takenori Niioka, Makoto Hayakari, Yoh Ishiguro, Shinsaku Fukuda
Biochemistry and biophysics reports 24 100811 - 100811 2020.12
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Diagnostic approach for patients with unidentified fever according to the classical criteria of fever of unknown origin in the field of autoimmune disorders.
Rina Watanabe, Hirotake Sakuraba, Hiroto Hiraga, Dai Kishida, Shinji Ota, Keisuke Hasui, Hidezumi Kikuchi, Yui Akemoto, Nahoko Tanaka, Takato Maeda, Yasuhisa Murai, Shukuko Yoshida, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Yoh Ishiguro, Shinsaku Fukuda
Immunological medicine 42 ( 4 ) 176 - 184 2019.12
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Long-term maintenance of the mucosal healing induced by azacitidine therapy in a patient with intestinal Behçet's-like disease accompanied with myelodysplastic syndrome involving trisomy 8.
Nahoko Tanaka, Hirotake Sakuraba, Hiroto Hiraga, Ko Mayama, Hidezumi Kikuchi, Dai Kishida, Yui Akemoto, Keisuke Hasui, Shinji Ota, Rina Watanabe, Yasuhisa Murai, Takato Maeda, Kosuke Kamata, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Kazufumi Yamagata, Yoh Ishiguro, Masanori Tanaka, Shinsaku Fukuda
Immunological medicine 42 ( 3 ) 135 - 141 2019.11
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A case of nivolumab-associated colitis, which relapsed after mucosal healing and was then successfully treated with mesalazine.
Hidezumi Kikuchi, Hirotake Sakuraba, Yui Akemoto, Yasuhisa Murai, Yukari Fukutoku, Taka Asari, Tetsuya Tatsuta, Keisuke Hasui, Hiroto Hiraga, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Masanori Tanaka, Shinsaku Fukuda
Immunological medicine 42 ( 1 ) 39 - 44 2019.3
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Vitamin A Deficiency Impairs Host Resistance to <i>Listeria Monocytogenes</i> Infection Through Excessive Apoptosis of Macrophages
Tanaka Nahoko, Yoshida Shukuko, Asano Krisana, Murai Yasuhisa, Fukuda Shinsaku, Watanabe Rina, Ota Shinji, Akemoto Yui, Hasui Keisuke
Hirosaki Medical Journal 69 ( 1-4 ) 163 - 171 2019.3
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Vitamin A deficiency impairs host resistance to Listeria Monocytogenes infection through excessive apoptosis of macrophages
Nahoko Tanaka, Hiroto Hiraga, Hirotake Sakuraba, Yasuhisa Murai, Takato Maeda, Rina Watanabe, Shinji Ota, Yui Akemoto, Keisuke Hasui, Shukuko Yoshida, Krisana Asano, Akio Nakane, Shinsaku Fukuda
Hirosaki Medical Journal 69 163 - 171 2019.3