Papers - HARA Yutaro
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Type 2 diabetes alters quiescent pancreatic stellate cells to tumor-prone state.
Yutaro Hara, Hiroki Mizukami, Takahiro Yamada, Shuji Shimoyama, Keisuke Yamazaki, Takanori Sasaki, Zhenchao Wang, Hanae Kushibiki, Masaki Ryuzaki, Saori Ogasawara, Hiroaki Tamba, Akiko Itaya, Norihisa Kimura, Keinosuke Ishido, Shinya Ueno, Kenichi Hakamada
JCI insight 10 ( 12 ) 2025.6
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MEG3 Promoter Methylation and F11 Receptor (F11R) Overexpression Define a High-Risk Subtype of Diabetic Pancreatic Cancer.
Yamazaki K, Mizukami H, Yamada T, Hara Y, Tamba H, Tatara Y, Wang Z, Itaya A, Kushibiki H, Ryuzaki M, Sasaki T, Ruike H, Ogasawara S, Tu Y, Ishido K, Itoh K, Hakamada K
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 39 ( 2 ) 100953 2026.2
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Esophageal Rupture in Recessive Dystrophic Epidermolysis Bullosa.
Hara Y, Muroya T, Hakamada K
Gastro hep advances 5 ( 4 ) 100885 2026
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Dual epigenetic changes in diabetes mellitus-associated pancreatic ductal adenocarcinoma correlate with downregulation of E-cadherin and worsened prognosis.
Yutaro Hara, Hiroki Mizukami, Keisuke Yamazaki, Takahiro Yamada, Akiko Igawa, Yuki Takeuchi, Takanori Sasaki, Hanae Kushibiki, Kotaro Murakami, Kazuhiro Kudoh, Keinosuke Ishido, Kenichi Hakamada
The journal of pathology. Clinical research 9 ( 5 ) 354 - 366 2023.9
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Dual epigenetic changes in diabetes mellitus-associated pancreatic ductal adenocarcinoma correlate with downregulation of E-cadherin and worsened prognosis
Yutaro Hara , Hiroki Mizukami, Keisuke Yamazaki , Takahiro Yamada, Akiko Igawa , Yuki Takeuchi, Takanori Sasaki, Hanae Kushibiki, Kotaro Murakami, Kazuhiro Kudoh, Keinosuke Ishido, Kenichi Hakamada
The Journal of Pathology: Clinical Research 2023.7
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Diabetes mellitus impacts on expression of DNA mismatch repair protein PMS2 and tumor microenvironment in pancreatic ductal adenocarcinoma
Xuekai Pan, Hiroki Mizukami, Yutaro Hara , Takahiro Yamada , Keisuke Yamazaki , Kazuhiro Kudoh, Yuki Takeuchi, Takanori Sasaki, Hanae Kushibiki, Akiko Igawa, Kenichi Hakamada
2023.1
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The diversity and abundance of gut microbiota are associated with the pain sensation threshold in the Japanese population
Yuki Takeuchi, Hiroki Mizukami, Kazuhiro Kudoh, Sho Osonoi, Takanori Sasaki, Hanae Kushibiki, Saori Ogasawara, Yutaro Hara, Akiko Igawa, Xuekai Pan, Takahiro Yamada, Keisuke Yamazaki, Tatsuya Mikami, Makoto Daimon, Soroku Yagihashi, Kenichi Hakamada, Shigeyuki Nakaji
2022.10
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Development of a Biomarker-Based Scoring System Predicting Early Recurrence of Resectable Pancreatic Duct Adenocarcinoma.
Keinosuke Ishido, Norihisa Kimura, Taiichi Wakiya, Hayato Nagase, Yutaro Hara, Taishu Kanda, Hiroaki Fujita, Kenichi Hakamada
Annals of surgical oncology 29 ( 2 ) 1281 - 1293 2022.2
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Diabetes in Humans Activates Pancreatic Stellate Cells via RAGE in Pancreatic Ductal Adenocarcinoma
Chiaki Uchida, Hiroki Mizukami, Yutaro Hara, Takeshi Saito, Satoko Umetsu, Akiko Igawa , Sho Osonoi, Kazuhiro Kudoh, Yasuhiko Yamamoto, Hiroshi Yamamoto, Soroku Yagihashi, Kenichi Hakamada
2021.10
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Short-term outcomes of robotic-assisted laparoscopic versus laparoscopic lateral lymph node dissection for advanced lower rectal cancer.
Hajime Morohashi, Yoshiyuki Sakamoto, Takuya Miura, Takuji Kagiya, Kenta Ogasawara, Yoshiya Takahashi, Kentaro Sato, Yutaro Hara, Hirokazu Ogasawara, Kenichi Hakamada
Surgical endoscopy 35 ( 9 ) 5001 - 5008 2021.9
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Inhibitory effects of xanthine oxidase inhibitor, topiroxostat, on development of neuropathy in db/db mice.
Kazuhisa Takahashi, Hiroki Mizukami, Sho Osonoi, Saori Ogasawara, Yutaro Hara, Kazuhiro Kudoh, Yuki Takeuchi, Takanori Sasaki, Makoto Daimon, Soroku Yagihashi
Neurobiology of disease 155 105392 - 105392 2021.7
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[A Case of Descending Colon and Rectal Cancer with Acute Myeloid Leukemia Performed Robot‒Assisted Hartmann's Procedure].
Hiroaki Fujita, Hajime Morohashi, Yoshiyuki Sakamoto, Takuya Miura, Kentaro Sato, Yuto Mitsuhashi, Kotaro Umemura, Hirokazu Ogasawara, Yutaro Hara, Taishu Kanda, Shunsuke Kubota, Yusuke Hagiwara, Kenichi Hakamada
Gan to kagaku ryoho. Cancer & chemotherapy 48 ( 4 ) 599 - 601 2021.4
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Organ/space infection is a common cause of high output stoma and outlet obstruction in diverting ileostomy.
Yutaro Hara, Takuya Miura, Yoshiyuki Sakamoto, Hajime Morohashi, Hayato Nagase, Kenichi Hakamada
BMC surgery 20 ( 1 ) 83 - 83 2020.4
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[Gallbladder Cancer with Multiple Liver Metastases Completely Responding to Gemcitabile plus Cisplatin Chemotherapy-A Case Report].
Hiroyuki Jin, Aika Ichisawa, Yusuke Hagiwara, Yutaro Hara, Toshiro Kimura, Shinnosuke Yonaiyama, Toru Yoshikawa, Makoto Nakai, Tomohisa Tokura, Kazunori Aoki, Hiroaki Kawashima, Yoshikazu Toyoki, Masaaki Endo
Gan to kagaku ryoho. Cancer & chemotherapy 47 ( 2 ) 364 - 366 2020.2
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A Case of Preserved Anorectal Function Even with Significant Defects of the Perianal Soft Tissue Induced by Aggressive Debridement for Fournier's Gangrene
Umemura Kotaro, Miura Takuya, Sakamoto Yoshiyuki, Morohash Hajime, Nagase Hayato, Hara Yutaro, Hakamada Kenichi
Nihon Fukubu Kyukyu Igakkai Zasshi (Journal of Abdominal Emergency Medicine) 40 ( 6 ) 787 - 790 2020
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[Successful Treatment of Necrotizing Fasciitis Due to Ascending Colon Cancer-A Case Report].
Aika Ichisawa, Hiroyuki Jin, Yusuke Hagiwara, Yutaro Hara, Toshiro Kimura, Shinnosuke Yonaiyama, Toru Yoshikawa, Makoto Nakai, Tomohisa Tokura, Kazunori Aoki, Hiroaki Kawashima, Yoshikazu Toyoki, Masaaki Endoh
Gan to kagaku ryoho. Cancer & chemotherapy 46 ( 13 ) 2574 - 2576 2019.12
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[A Case of Liver Recurrence of Choriocarcinoma and AFP-Producing Carcinoma of the Stomach Showing a Complete Histological Response after Chemotherapy].
Nakai M, Hara Y, Yonaiyama S, Jin H, Tokura T, Aoki K, Kawashima H, Toyoki Y, Endo M
Gan to kagaku ryoho. Cancer & chemotherapy 46 ( 1 ) 151 - 153 2019.1
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＜一般演題抄録＞多発肝転移を伴う切除不能膵癌に対してFOLFIRINOX療法が著効しconversion surgeryを施行し得た１例
小笠原 宏一, 高畑 武功, 佐藤 温, 袴田 健一, 石戸 圭之輔, 原 裕太郎, 赤石 隆信, 工藤 大輔, 木村 憲央, 米内山 真之介, 陳 豫, 斎藤 絢介
弘前医学 70 ( 1 ) 94 - 94 2019
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〈一般演題抄録〉骨格筋量の推移からみた胸腔鏡下食道切除術の有用性の検討
原 裕太郎, 室谷 隆裕, 和嶋 直紀, 久保 寛仁, 吉田 枝里, 袴田 健一
弘前医学 69 ( 1 ) 2019
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[A Case of Advanced Gastric Cancer with Peritoneal Dissemination after Gastrectomy Effectively Treated with Combination Chemotherapy of Ramucirumab and Paclitaxel].
Muroya T, Wajima N, Kubo N, Yoshida E, Akaishi T, Umetsu S, Yoshida T, Wakasa Y, Sato K, Mitsuhashi Y, Umemura K, Ogasawara H, Hara Y, Hakamada K
Gan to kagaku ryoho. Cancer & chemotherapy 45 ( 13 ) 2066 - 2068 2018.12
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[Outcomes of Total Mesorectal Excision and Lateral Lymph Node Dissection following Neoadjuvant Chemotherapy for Lower Rectal Cancer with Lateral Lymph Node Metastasis].
Morohashi H, Uchida C, Ogasawara H, Hara Y, Akaishi T, Yachi T, Wakasa Y, Mitsuhashi Y, Tsuruta S, Sato K, Yoshida T, Umetsu S, Hasebe T, Suto A, Hakamada K
Gan to kagaku ryoho. Cancer & chemotherapy 45 ( 13 ) 1803 - 1805 2018.12
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[A Case of Perforated Gastric Cancer Treated with Curative Resection Following Conservative Medical Management and Chemotherapy].
Mitsuhashi Y, Muroya T, Wajima N, Kubo N, Yoshida E, Hara Y, Hakamada K
Gan to kagaku ryoho. Cancer & chemotherapy 45 ( 13 ) 1836 - 1838 2018.12