Desumoylation Activity of Axam, a Novel Axin-Binding Protein, Is Involved in Downregulation of β-Catenin

Takayuki Kadoya, Hideki Yamamoto, Toshiaki Suzuki, Akira Yukita, Akimasa Fukui, Tatsuo Michiue, Toshimasa Asahara, Keiji Tanaka, Makoto Asashima, Akira Kikuchi

Molecular and Cellular Biology   22 ( 11 )   3803 - 3819   2002.6

Etiology, pathogenesis, and genetics of Parkinson's disease

Y Mizuno, N Hattori, H Shimura, T Kitada, S Kubo, M Wang, K Sato, T Suzuki, T Chiba, K Tanaka, S Asakawa, S Minoshima, N Shimizu

MAPPING THE PROGRESS OF ALZHEIMER'S AND PARKINSON'S DISEASE   51   239 - 244   2002

Ubiquitin-proteasome pathway is a key to understanding of nigral degeneration in autosomal recessive juvenile Parkinson's disease

N Hattori, S Asakawa, H Shimura, S Kubo, K Sato, T Kitami, Y Chikaoka-Kwamura, Y Imai, R Takahashi, T Suzuki, K Tanaka, N Shimizu, Y Mizuno

MAPPING THE PROGRESS OF ALZHEIMER'S AND PARKINSON'S DISEASE   51   291 - 296   2002

Anti-atherogenic Antioxidants Regulate the Expression and Function of Proteasome α-Type Subunits in Human Endothelial Cells

Wakako Takabe, Tatsuhiko Kodama, Takao Hamakubo, Keiji Tanaka, Toshiaki Suzuki, Hiroyuki Aburatani, Naeko Matsukawa, Noriko Noguchi

Journal of Biological Chemistry   276 ( 44 )   40497 - 40501   2001.11

Parkin is linked to the ubiquitin pathway

K Tanaka, T Suzuki, T Chiba, H Shimura, N Hattori, Y Mizuno

JOURNAL OF MOLECULAR MEDICINE-JMM   79 ( 9 )   482 - 494   2001.9

NEDD8 recruits E2-ubiquitin to SCF E3 ligase

T Kawakami, T Chiba, T Suzuki, K Iwai, K Yamanaka, N Minato, H Suzuki, N Shimbara, Y Hidaka, F Osaka, M Omata, K Tanaka

EMBO JOURNAL   20 ( 15 )   4003 - 4012   2001.8

Parkin and Parkinson's disease

Y Mizuno, N Hattori, H Mori, T Suzuki, K Tanaka

CURRENT OPINION IN NEUROLOGY   14 ( 4 )   477 - 482   2001.8

Developmental changes in the expression of parkin and UbcR7, a parkin-interacting and ubiquitin-conjugating enzyme, in rat brain

M Wang, T Suzuki, T Kitada, S Asakawa, S Minoshima, N Shimizu, K Tanaka, Y Mizuno, N Hattori

JOURNAL OF NEUROCHEMISTRY   77 ( 6 )   1561 - 1568   2001.6

Rma1, a novel type of RING finger protein conserved from <i>Arabidopsis</i> to human, is a membrane-bound ubiquitin ligase

Matsuda N, Suzuki T, Tanaka K, Nakano A

JOURNAL OF CELL SCIENCE   114 ( 10 )   1949 - 1957   2001.5

Rma1, a novel type of RING finger protein conserved from Arabidopsis to human, is a membrane-bound ubiquitin ligase

N Matsuda, T Suzuki, K Tanaka, A Nakano

JOURNAL OF CELL SCIENCE   114 ( 10 )   1949 - 1957   2001.5

A novel centrosomal RING-finger protein, Dorfin, mediates ubiquitin ligase activity

J Niwa, S Ishigaki, M Doyu, T Suzuki, K Tanaka, G Sobue

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   281 ( 3 )   706 - 713   2001.3

Autosomal recessive juvenile parkinsonism: A key to understanding nigral degeneration in sporadic Parkinson's disease

N Hattori, H Shimura, S Kubo, T Kitada, M Wang, S Asakawa, S Minashima, N Shimizu, T Suzuki, K Tanaka, Y Mizuno

NEUROPATHOLOGY   20   S85 - S90   2000.9

Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast

F Osaka, M Saeki, S Katayama, N Aida, A Toh-e, K Kominami, T Toda, T Suzuki, T Chiba, K Tanaka, S Kato

EMBO JOURNAL   19 ( 13 )   3475 - 3484   2000.7

Tissue-specificity, functional characterization and subcellular localization of a rat ubiquitin-specific processing protease, UBP109, whose mRNA expression is developmentally regulated

KC Park, EJ Choi, SW Min, SS Chung, H Kim, T Suzuki, K Tanaka, CH Chung

BIOCHEMICAL JOURNAL   349 ( Pt 2 )   443 - 453   2000.7

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

H Shimura, N Hattori, S Kubo, Y Mizuno, S Asakawa, S Minoshima, N Shimizu, K Iwai, T Chiba, K Tanaka, T Suzuki

NATURE GENETICS   25 ( 3 )   302 - 305   2000.7

A new SUMO-1-specific protease, SUSP1, that is highly expressed in reproductive organs

KI Kim, SH Baek, YJ Jeon, S Nishimori, T Suzuki, S Uchida, N Shimbara, H Saitoh, K Tanaka, CH Chung

JOURNAL OF BIOLOGICAL CHEMISTRY   275 ( 19 )   14102 - 14106   2000.5

Homodimer of two F-box proteins beta TrCP1 or beta TrCP2 binds to I kappa B alpha for signal-dependent ubiquitination

H Suzuki, T Chiba, T Suzuki, T Fujita, T Ikenoue, M Omata, K Furuichi, H Shikama, K Tanaka

JOURNAL OF BIOLOGICAL CHEMISTRY   275 ( 4 )   2877 - 2884   2000.1

Autosomal recessive juvenile parkinsonism: Its pathogenesis is involved in the ubiquitin-proteasome pathway

N. Hattori, H. Shimura, S. I. Kubo, T. Suzuki, K. Tanaka, Y. Mizuno

Clinical Neurology   40 ( 12 )   1293 - 1296   2000

A new 30-kDa ubiquitin-related SUMO-1 hydrolase from bovine brain

T Suzuki, A Ichiyama, H Saitoh, T Kawakami, M Omata, CH Chung, M Kimura, N Shimbara, K Tanaka

JOURNAL OF BIOLOGICAL CHEMISTRY   274 ( 44 )   31131 - 31134   1999.10

Isolation and characterization of cytosolic and membrane-bound deubiquitinylating enzymes from bovine brain

T Kawakami, T Suzuki, SH Baek, CH Chung, H Kawasaki, H Hirano, A Ichiyama, M Omata, K Tanaka

JOURNAL OF BIOCHEMISTRY   126 ( 3 )   612 - 623   1999.9

IκBα ubiquitination is catalyzed by an SCF-like complex containing Skp1, cullin-1, and two F-box/WD40-repeat proteins, βTrCP1 and βTrCP2

Suzuki H, Chiba T, Kobayashi M, Takeuchi M, Suzuki T, Ichiyama A, Ikenoue T, Omata M, Furuichi K, Tanaka K

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   256 ( 1 )   127 - 132   1999.3

I kappa B alpha ubiquitination is catalyzed by an SCF-like complex containing Skp1, cullin-1, and two F-box/WD40-repeat proteins, beta TrCP1 and beta TrCP2

H Suzuki, T Chiba, M Kobayashi, M Takeuchi, T Suzuki, A Ichiyama, T Ikenoue, M Omata, K Furuichi, K Tanaka

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   256 ( 1 )   127 - 132   1999.3

Identification and chromosomal assignment of USP1, a novel gene encoding a human ubiquitin-specific protease

T Fujiwara, A Saito, M Suzuki, H Shinomiya, T Suzuki, E Takahashi, A Tanigami, A Ichiyama, CH Chung, Y Nakamura, K Tanaka

GENOMICS   54 ( 1 )   155 - 158   1998.11

The ligation systems for ubiquitin and ubiquitin-like proteins

K Tanaka, T Suzuki, T Chiba

MOLECULES AND CELLS   8 ( 5 )   503 - 512   1998.10

Energy-dependent degradation of a mutant serine: Pyruvate alanin: Glyoxylate aminotransferase in a primary hyperoxaluria type 1 case

T Suzuki, K Nishiyama, T Funai, K Tanaka, A Ichihara, A Ichiyama

INTRACELLULAR PROTEIN CATABOLISM   389   137 - 140   1996

Parkin ubiquitination activity in vitro: From a study using CDCrel-I

T Kitami, K Sato, T Suzuki, N Hattori, K Tanaka, Y Mizuno

MOVEMENT DISORDERS   17   S153 - S153   2002

ユビキチンリガーゼとしてのparkinとParkinson病--家族性Parkinson病から孤発型Parkinson病へ (〔2001年8月〕第1土曜特集 神経疾患の分子医学) -- (神経変性疾患)

服部 信孝, 鈴木 俊顕, 高橋 良輔

医学のあゆみ   198 ( 5 )   383 - 388   2001.8

ユビキチン類似タンパク質(SUMO-1とRub1)細胞機能を制御する新しい修飾分子 (特集 ユビキチンシステムと癌)

鈴木 俊顕, 高橋 芳充, 田中 克典

モレキュラ-メディシン   37 ( 2 )   216 - 227   2000.2