Establishment of a recessive mutant small-eye rat with lens involution and retinal detachment associated with partial deletion and rearrangement of the Cryba1 gene.

Toshiyuki Yamada, Naoki Nanashima, Takeshi Shimizu, Yosuke Nakazawa, Mitsuru Nakazawa, Shigeki Tsuchida

The Biochemical journal   471 ( 2 )   293 - 305   2015.10

Deletion of phospholipase A2 group IVc induces apoptosis in rat mammary tumour cells by the nuclear factor-κB/lipocalin 2 pathway.

Naoki Nanashima, Toshiyuki Yamada, Takeshi Shimizu, Shigeki Tsuchida

The Biochemical journal   469 ( 2 )   315 - 324   2015.7

Fatty acid synthase-positive hepatocytes and subsequent steatosis in rat livers by irinotecan.

Takeyuki Sawano, Takeshi Shimizu, Toshiyuki Yamada, Naoki Nanashima, Takuya Miura, Satoko Morohashi, Daisuke Kudo, Feng Mao Hui, Hiroshi Kijima, Kenichi Hakamada, Shigeki Tsuchida

Oncology reports   33 ( 5 )   2151 - 2160   2015.5

Angiogenesis of interlobular hepatic arteries and veins and the expression of 15-hydroxyprostaglandin dehydrogenase in peroxisome proliferator-induced rat hepatomegaly

Shimizu T, Nanashima N, Yamada T, Tsuchida S.

Molecular Tumor Marker Research   2015.3

Variation of Kupffer cells and expression of phospholipase A2 during peroxisome proliferator-induced rat hepatocarcinogenesis.

Shimizu T, Nanashima N, Sawano T, Yamada T, Tsuchida S.

Molecular Tumor Marker Research   2014.4

Homologous pairing activities of two rice RAD51 proteins, RAD51A1 and RAD51A2.

Yuichi Morozumi, Ryohei Ino, Shukuko Ikawa, Naozumi Mimida, Takeshi Shimizu, Seiichi Toki, Hiroaki Ichikawa, Takehiko Shibata, Hitoshi Kurumizaka

PloS one   8 ( 10 )   e75451 - e75451   2013.10

Lectin-like receptor Ly49s3 on dendritic cells contributes to the differentiation of regulatory T cells in the rat thymus.

Toshiyuki Yamada, Naoki Nanashima, Miki Akita, Takeshi Shimizu, Takuya Miura, Daisuke Yamana, Takeyuki Sawano, Takuya Sakurai, Shigeki Tsuchida

Journal of immunology (Baltimore, Md. : 1950)   191 ( 7 )   3799 - 3809   2013.10

The relationship between the appearance of CD34-positive cells and the loss of hepatic stellate cells in peroxisome proliferator-treated rat livers.

Shimizu T, Nanashima N, Sawano T, Yamada T, Tsuchida S.

Molecular Tumor Marker Research   2013.3

The appearance of CD34-positive progenitor cells during rat hepatocarcinogenesis induced by peroxisome proliferator.

Shimizu T, Nanashima N, Yamada T, Tsuchida S.

Molecular Tumor Marker Research   2012.2

Sustained repression and translocation of Ntcp and expression of Mrp4 for cholestasis after rat 90% partial hepatectomy.

Miura T, Kimura N, Yamada T, Shimizu T, Nanashima N, Yamana D, Hakamada K, Tsuchida S.

J. Hepatol.   2011.8

Decrease of hepatic stellate cells in rats with enhanced sensitivity to clofibrate-induced hepatocarcinognenesis.（共著）

Yamana D, Shimizu T, Fan Y, Miura T, Nanashima N, Yamada T, Hakamada K, Tsuchida S.

Cancer Sci.   2011.4

The multistep carcinogenesis for rat livers induced by a peroxisome proliferator clofibrate. "jointly worked"

Shimizu T, Yamana D, Nanashima N, Yamada T, Miura T, Tsuchida S.

Molecular Tumor Marker Research   2011.1

Glutathione S-transferase A4 is a positive marker for rat hepatic foci induced by clofibrate and genotoxic carcinogens.（共著）

Shimizu T, Fan Y, Yamana D, Miura T, Nanashima N, Yamada T, Tsuchida S.

Cancer Sci.   2010.5

Histone acetylation and steroid receptor coactivator expression during clofibrate-induced rat hepatocarcinogenesis.（共著）

Asano J, Kudo T, Shimizu T, Fan Y, Nanashima N, Yamana D, Miura T, Yamada T, Tsuchida S.

Cancer Sci.   2010.4

The analysis of transcription factors involved in GSTA4-4 expression in rat hepatic preneoplastic lesions induced by genotoxic and non-genotoxic carcinogens. "jointly worked"

Shimizu T, Nanashima N, Yamada T, Miura T, Yamana D, Tsuchida S.

Molecular Tumor Marker Research   2010.2

Physical and functional interactions between hematopoietic cell-specific ETS transcription factors and homeodomain proteins.

Yamada T, Shimizu T, Sakurai T, Nanashima N, Kihara-Negishi F, Suzuki M, Fan Y, Akita M, Oikawa T, Tsuchida S.

Leuk. Res.   2009.3

Characterization of hair follicles in Hirosaki Hairless Rats with deletion of basic hair keratin genes. Enlarged medulla, loss of cuticle and long catagen.

Akita M, Nanashima N, Yamada T, Nakano H, Shimizu T, Fan Y, Tsuchida S.

Hirosaki Med. J.   2009.3

Ferritin expression in rat hepatocytes and Kupffer cells after lead nitrate treatment.

Fan Y, Yamada T, Shimizu T, Nanashima N, Akita M, Suto K, Tsuchida S.

Toxicol. Pathol.   2009.3

Glutathione S-transferase (GST) A4-4 is a positive marker for rat hepatic foci induced by non-genotoxic and genotoxic carcinogens. "jointly worked"

Shimizu T, Fan Y, Nanashima N, Akita M, Yamada T, Tsuchida S.

Molecular Tumor Marker Research   2009.2

The hairless phenotype of the Hirosaki Hairless Rat is due to the deletion of an 80-kb genomic DNA containing five basic keratin genes.

Nanashima N, Akita M, Yamada T, Shimizu T, Nakano H, Fan Y, Tsuchida S.

J. Biol. Chem.   2008.6

Glutathione S-transferase (GST) A4-4 is a possile positive marker for preneoplastic lesions induced by peroxisome proliferators (PP). "jointly worked"

Shimizu T, Nanashima N, Fan Y, Akita M, Yamada T, Tsuchida S.

Journal of Japan Society for Molecular Tumor Marker Research   2008.3

Development of glutathione S-transferase-P-negative foci accompanying nuclear factor-erythroid 2-related factor 2 expression during early stage of rat hepatocarcinogenesis.（共著）

Fan Y, Shimizu T, Yamada T, Nanashima N, Akita M, Asano J, Tsuchida S.

Cancer Sci.   2008.3

Interaction between the homeodomain protein HOXC13 and ETS family transcription factor PU.1 and its implication in the differentiation of murine erythroleukemia cells.（共著）

Yamada T, Shimizu T, Suzuki M, Kihara-Negishi F, Nanashima N, Sakurai T, Fan Y, Akita M, Oikawa T, Tsuchida S.

Exp. Cell Res.   2008.2

Factors involved in different inducibilities of hepatic bifunctional enzyme by peroxisome proliferators in rats with polymorphic glutathione transferase gene. "jointly worked"

Shimizu T, Asano J, Nanashima N, Fan Y, Akita M, Yamada T, Tsuchida S.

Journal of Japan Society for Molecular Tumor Marker Research   2007.4

Different susceptibility to peroxisome proliferators induced hepatocarcinogenesis in rats with polymorphic glutathione transferase genes.（共著）

Kudo T, Asano J, Shimizu T, Nanashima N, Fan Y, Akita M, Ookawa K, Hayakari M, Yokoyama Y, Suto K, Tsuchida S.

Cancer Sci.   2006.8

Loss of carbonic anhydrase 3 expression in rat preneoplastic hepatic lesions induced by peroxisome proliferator. "jointly worked"

Shimizu T, Kudo T, Asano J, Nanashima N, Fan Y, Yamada T, Tsuchida S.

Journal of Japan Society for Molecular Tumor Marker Research   2006.5

Nuclear localization of STAT5A modified with O-linked N-acetylglucosamine and early involution in the mammary gland of hirosaki hairless rat.（共著）

Nanashima N, Asano J, Hayakari M, Nakamura T, Nakano H, Yamada T, Shimizu T, Akita M, Fan Y, Tsuchida S.

J. Biol. Chem.   2005.12

Different susceptibility to clofibrate-induced hepatocarcinogenesis in rats with genetic polymorphism of Mu-class glutathione transferases. "jointly worked"

Tsuchida S, Kudo T, Asano J, Mayama J, Shimizu T, Fan Y, Hayakari M.

Journal of Japan Society for Molecular Tumor Marker Research   2005.8

High-throughput in planta expression screening identifies a class II ethylene-responsive element binding factor-like protein that regulates plant cell death and non-host resistance.（共著）

Nasir KH, Takahashi Y, Ito A, Saitoh H, Matsumura H, Kanzaki H, Shimizu T, Ito M, Fujisawa S, Sharma PC, Ohme-Takagi M, Kamoun S, Terauchi R.

Plant J.   2005.8

Virus-induced silencing of WIPK and SIPK genes reduces resistance against a bacterial pathogen but no effect on INF1-induced HR in Nicotiana benthamiana.（共著）

Sharma PC, Ito A, Shimizu T, Terauchi R, Kamoun S, Saitoh H.

Mol. Gen. Genomics   2003.8