Papers - SEYA KAZUHIKO
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The inhibitory effect of DIF-3 on polyinosinic-polycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells.
Araya R, Men S, Uekusa Y, Yu Z, Kikuchi H, Daitoku K, Minakawa M, Kawaguchi S, Furukawa KI, Oshima Y, Imaizumi T, Seya K
Journal of pharmacological sciences 154 ( 3 ) 157 - 165 2024.3
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Resiquimod induces C-C motif chemokine ligand 2 via nuclear factor-kappa B in SH-SY5Y human neuroblastoma cells
Masatoshi Kaizuka, Shogo Kawaguchi, Tetsuya Tatsuta, Mayuki Tachizaki, Yuri Kobori, Yusuke Tanaka, Kazuhiko Seya, Tomoh Matsumiya, Tadaatsu Imaizumi, Hirotake Sakuraba
NeuroMolecular Medicine 2024.3
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Possible involvement of DExD/H box helicase 60 in synovial inflammation of rheumatoid arthritis: role of toll-like receptor 3 signaling.
Nakamura Y, Ishibashi HK, Saruga T, Imaizumi T, Kurose A, Tachizaki M, Kawaguchi S, Seya K, Sasaki E, Ishibashi Y
Molecular biology reports 51 ( 1 ) 131 2024.1
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Expression of interferon-stimulated gene 20 (ISG20), an antiviral effector protein, in glomerular endothelial cells: possible involvement of ISG20 in lupus nephritis.
Karasawa T, Sato R, Imaizumi T, Fujita M, Aizawa T, Tsugawa K, Mattinzoli D, Kawaguchi S, Seya K, Terui K, Joh K, Tanaka H
Renal failure 45 ( 1 ) 2224890 2023.12
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Wnt5a pathway was not involved in the progression of valve calcification in calcific aortic valve stenosis
Yu, Zaiqiang ; Daitoku, Kazuyuki ; Fukuda, Ikuo ; Imaizumi, Tadaatsu ; Minakawa, Masahito ; Furukawa, Ken-Ichi ; Seya, Kazuhiko
Hirosaki Medical Journal 2023.3
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Polygonum tinctorium leaf extract ameliorates high-fat diet-induced intestinal epithelial damage in mice.
Kawaguchi S, Sakuraba H, Kikuchi H, Matsuki K, Hayashi Y, Ding J, Tanaka Y, Seya K, Matsumiya T, Hiraga H, Fukuda S, Sasaki K, Imaizumi T
Experimental and therapeutic medicine 25 ( 3 ) 112 2023.3
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The double-stranded RNA-dependent protein kinase PKR negatively regulates the protein expression of IFN-β induced by RIG-I signaling.
Matsumiya T, Shiba Y, Ding J, Kawaguchi S, Seya K, Imaizumi T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 37 ( 2 ) e22780 2023.2
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Corrigendum to "Elucidation of the inhibitory effect of (+)-hopeaphenol on polyinosinicepolycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells" [Journal of Pharmacological Sciences 149 (2022) 147-157].
Xu L, Yu Z, Uekusa Y, Kawaguchi S, Kikuchi H, Daitoku K, Minakawa M, Motomura S, Furukawa KI, Oshima Y, Seya K, Imaizumi T
Journal of pharmacological sciences 151 ( 1 ) 63 - 64 2023.1
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ER export signals mediate plasma membrane localization of transmembrane protein TMEM72.
Ding J, Matsumiya T, Miki Y, Hayakari R, Shiba Y, Kawaguchi S, Seya K, Imaizumi T
The FEBS journal 2022.12
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Glomerular endothelial expression of type I IFN-stimulated gene, DExD/H-Box helicase 60 via toll-like receptor 3 signaling: possible involvement in the pathogenesis of lupus nephritis.
Karasawa T, Sato R, Imaizumi T, Hashimoto S, Fujita M, Aizawa T, Tsugawa K, Kawaguchi S, Seya K, Terui K, Tanaka H
Renal failure 44 ( 1 ) 137 - 145 2022.12
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Toll-like receptor 3 signaling induces interferon-induced transmembrane protein 1 in BEAS-2B cells.
Dobashi M, Shiratori T, Imaizumi T, Hashimoto S, Kawaguchi S, Seya K, Tasaka S
Experimental biology and medicine (Maywood, N.J.) 247 ( 21 ) 1917 - 1922 2022.11
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Tryptanthrin attenuates TLR3-mediated STAT1 activation in THP-1 cells.
Numao N, Kawaguchi S, Ding J, Karasawa T, Seya K, Matsumiya T, Kikuchi H, Sakuraba H, Fukuda S, Imaizumi T
Immunologic research 70 ( 5 ) 688 - 697 2022.10
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Elucidation of the inhibitory effect of (+)-hopeaphenol on polyinosinic-polycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells.
Xu L, Yu Z, Uekusa Y, Kawaguchi S, Kikuchi H, Daitoku K, Minakawa M, Motomura S, Furukawa KI, Oshima Y, Seya K, Imaizumi T
Journal of pharmacological sciences 149 ( 3 ) 147 - 157 2022.7
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Porphyromonas gingivalis lipopolysaccharide induces interleukin-6 and c-c motif chemokine ligand 2 expression in cultured hCMEC/D3 human brain microvascular endothelial cells.
Sato N, Matsumoto T, Kawaguchi S, Seya K, Matsumiya T, Ding J, Aizawa T, Imaizumi T
Gerodontology 39 ( 2 ) 139 - 147 2022.6
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Hepatic Macrophages Express Melanoma Differentiation-Associated Gene 5 in Nonalcoholic Steatohepatitis.
Kawaguchi S, Sakuraba H, Horiuchi M, Ding J, Matsumiya T, Seya K, Iino C, Endo T, Kikuchi H, Yoshida S, Hiraga H, Fukuda S, Imaizumi T
Inflammation 45 ( 1 ) 343 - 355 2022.2
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Effect of sera from lupus patients on the glomerular endothelial fibrinolysis system.
Sato R, Aizawa T, Imaizumi T, Tsugawa K, Kawaguchi S, Seya K, Terui K, Tanaka H
Pediatrics international : official journal of the Japan Pediatric Society 64 ( 1 ) e15099 2022.1
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Ketamine Does Not Change Natural Killer Cell Cytotoxicity in Patients Undergoing Cancer Surgery: Basic Experiment and Clinical Trial.
Kubota M, Niwa H, Seya K, Kawaguchi J, Kushikata T, Hirota K
Journal of oncology 2022 8946269 2022
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Expression of Zinc-Finger Antiviral Protein in hCMEC/D3 Human Cerebral Microvascular Endothelial Cells: Effect of a Toll-Like Receptor 3 Agonist.
Okudera M, Odawara M, Arakawa M, Kawaguchi S, Seya K, Matsumiya T, Sato R, Ding J, Morita E, Imaizumi T
Neuroimmunomodulation 29 ( 4 ) 1 - 10 2021.12
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Inhibitory effect of anti-malarial agents on the expression of proinflammatory chemokines via Toll-like receptor 3 signaling in human glomerular endothelial cells.
Sato R, Imaizumi T, Aizawa T, Watanabe S, Tsugawa K, Kawaguchi S, Seya K, Matsumiya T, Tanaka H
Renal failure 43 ( 1 ) 643 - 650 2021.12
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Expression of IFN-induced transmembrane protein 1 in glomerular endothelial cells.
Hashimoto S, Imaizumi T, Watanabe S, Aizawa T, Tsugawa K, Kawaguchi S, Seya K, Matsumiya T, Tanaka H
Pediatrics international : official journal of the Japan Pediatric Society 63 ( 9 ) 1075 - 1081 2021.9
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Daily Brazilian green propolis intake elevates blood artepillin C levels in humans.
Ding J, Matsumiya T, Hayakari R, Shiba Y, Kawaguchi S, Seya K, Ueno K, Imaizumi T
Journal of the science of food and agriculture 101 ( 11 ) 4855 - 4861 2021.8
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Interleukin-6 via Toll-Like Receptor 3 Signaling Attenuates the Expression of Proinflammatory Chemokines in Human Podocytes.
Umetsu H, Watanabe S, Imaizumi T, Aizawa T, Tsugawa K, Kawaguchi S, Seya K, Matsumiya T, Tanaka H
Kidney & blood pressure research 46 ( 2 ) 207 - 218 2021
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Preliminary study on local medical treatment of aortic valve calcification: Drug delivery to aortic valve in rat
Yu Zaiqiang, Liu Xu, Daitoku Kazuyuki, Furukawa Ken-Ichi, Fukuda Ikuo, Motomura Shigeru, Seya Kazuhiko
Hirosaki Medical Journal 71 ( 2-4 ) 101 - 107 2021
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Expression of IFN-induced Transmembrane Protein 1 in Glomerular Endothelial Cells.
Shun Hashimoto, Tadaatsu Imaizumi, Shojiro Watanabe, Tomomi Aizawa, Koji Tsugawa, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Hiroshi Tanaka
Pediatrics international : official journal of the Japan Pediatric Society 2020.12
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Endothelial expression of fractalkine (CX3CL1) is induced by Toll-like receptor 3 signaling in cultured human glomerular endothelial cells.
Hirono K, Imaizumi T, Aizawa T, Watanabe S, Tsugawa K, Shiratori T, Kawaguchi S, Seya K, Matsumiya T, Ito E, Tanaka H
Modern rheumatology 30 ( 6 ) 1074 - 1081 2020.11
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Correction to: Warfarin calcifies human aortic valve interstitial cells at high-phosphate conditions via pregnane X receptor.
Yu Z, Seya K, Chiyoya M, Daitoku K, Motomura S, Imaizumi T, Fukuda I, Furukawa KI
Journal of bone and mineral metabolism 38 ( 3 ) 418 - 419 2020.5
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ISG56 is involved in CXCL10 expression induced by TLR3 signaling in BEAS-2B bronchial epithelial cells.
Shiratori T, Imaizumi T, Hirono K, Kawaguchi S, Matsumiya T, Seya K, Tasaka S
Experimental lung research 46 ( 6 ) 195 - 202 2020.5
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Menaquinone-4 Accelerates Calcification of Human Aortic Valve Interstitial Cells in High-Phosphate Medium through PXR.
Yang W, Yu Z, Chiyoya M, Liu X, Daitoku K, Motomura S, Imaizumi T, Fukuda I, Furukawa KI, Tsuji M, Seya K
The Journal of pharmacology and experimental therapeutics 372 ( 3 ) 277 - 284 2020.3
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Interferon-induced transmembrane protein 1 and Myxovirus resistance protein 1 are induced by polyinosinic-polycytidylic acid in cultured hCMEC/D3 human cerebral microvascular endothelial cells.
Imaizumi T, Satake U, Miyashita R, Kawaguchi S, Matsumiya T, Seya K, Ding J, Tanaka H
Journal of neuroimmunology 337 577047 2019.12
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Melanoma Differentiation-Associated Gene 5 Positively Modulates TNF-α-Induced CXCL10 Expression in Cultured HuH-7 and HLE Cells.
Kawaguchi, Sakuraba H, Haga T, Matsumiya T, Seya K, Endo T, Sawada N, Iino C, Kikuchi H, Hiraga H, Fukuda S, Imaizumi
Inflammation 2019.12
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Endothelial expression of fractalkine (CX3CL1) is induced by Toll-like receptor 3 signaling in cultured human glomerular endothelial cells.
Hirono K, Imaizumi T, Aizawa T, Watanabe S, Tsugawa K, Shiratori T, Kawaguchi S, Seya K, Matsumiya T, Ito E, Tanaka H.
Modern Rheumatology 2019.11
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Warfarin calcifies human aortic valve interstitial cells at high-phosphate conditions via pregnane X receptor.
Yu Z, Seya K, Chiyoya M, Daitoku K, Motomura S, Imaizumi T, Fukuda I, Furukawa KI
Journal of bone and mineral metabolism 37 ( 6 ) 944 - 956 2019.11
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Cytosolic Sensors of Viral RNA Are Involved in the Production of Interleukin-6 via Toll-Like Receptor 3 Signaling in Human Glomerular Endothelial Cells.
Qiang Liu, Tadaatsu Imaizumi, Tomomi Aizawa, Koji Hirono, Shogo Kawaguchi, Shojiro Watanabe, Koji Tsugawa, Tomoh Matsumiya, Kazuhiko Seya, Hidemi Yoshida, Hiroshi Tanaka
Kidney & blood pressure research 44 ( 1 ) 62 - 71 2019.1
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Effect of low-concentration amyloid-β 1–42 (Aβ42) on human neuroblastoma SH-SY5Y cell viability: neuroprotective potential of combination use with carnosic acid, rebamipide, edaravone, and resveratrol
Yoshida Hidemi, Hashimoto Yuko, Fukushima Takashi, Tanji Kunikazu, Matsumiya Tomoh, Seya Kazuhiko, Kawaguchi Shogo, Imaizumi Tadaatsu
Hirosaki Medical Journal 70 ( 1 ) 24 - 38 2019
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Interferon-stimulated gene 60 (ISG60) constitutes a negative feedback loop in the downstream of TLR3 signaling in hCMEC/D3 cells.
Tadaatsu Imaizumi, Naoko Sassa, Shogo Kawaguchi, Tomoh Matsumiya, Hidemi Yoshida, Kazuhiko Seya, Toshihiro Shiratori, Koji Hirono, Hiroshi Tanaka
Journal of neuroimmunology 324 16 - 21 2018.11
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Interferon-stimulated gene 60 (ISG60) constitutes a negative feedback loop in the downstream of TLR3 signaling in hCMEC/D3 cells.
Imaizumi T, Sassa N, Kawaguchi S, Matsumiya T, Yoshida H, Seya K, Shiratori T, Hirono K, Tanaka H
Journal of neuroimmunology 324 16 - 21 2018.11
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<b>Gnetin C suppresses double-stranded RNA-induced C-C motif chemokine ligand 2 (CCL2) and CCL5 production by inhibiting Toll-like receptor 3 signaling </b><b>pathway </b>
YOSHIDA Hidemi, IMAIZUMI Tadaatsu, MATSUMIYA Tomoh, SEYA Kazuhiko, KAWAGUCHI Shogo, TANAKA Hiroshi
Biomedical Research 39 ( 5 ) 231 - 240 2018.10
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<b>Gnetin C, a resveratrol dimer, reduces amyloid-β 1–42 (Aβ42) production and ameliorates Aβ42-lowered cell viability in cultured SH-SY5Y human neuroblastoma </b><b>cells </b>
SEINO Syota, KIMOTO Takeru, YOSHIDA Hidemi, TANJI Kunikazu, MATSUMIYA Tomoh, HAYAKARI Ryo, SEYA Kazuhiko, KAWAGUCHI Shogo, TSURUGA Kazushi, TANAKA Hiroshi, IMAIZUMI Tadaatsu
Biomedical Research 39 ( 3 ) 105 - 115 2018.6
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Gnetin C suppresses double-stranded RNA-induced C-C motif chemokine ligand 2 (CCL2) and CCL5 production by inhibiting Toll-like receptor 3 signaling pathway.
Hidemi Yoshida, Tadaatsu Imaizumi, Tomoh Matsumiya, Kazuhiko Seya, Shogo Kawaguchi, Hiroshi Tanaka
Biomedical research (Tokyo, Japan) 39 ( 5 ) 231 - 240 2018.5
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Matrix Gla protein negatively regulates calcification of human aortic valve interstitial cells isolated from calcified aortic valves.
Mari Chiyoya, Kazuhiko Seya, Zaiqiang Yu, Kazuyuki Daitoku, Shigeru Motomura, Tadaatsu Imaizumi, Ikuo Fukuda, Ken-Ichi Furukawa
Journal of pharmacological sciences 136 ( 4 ) 257 - 265 2018.4
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Matrix Gla protein negatively regulates calcification of human aortic valve interstitial cells isolated from calcified aortic valves.
Chiyoya M, Seya K, Yu Z, Daitoku K, Motomura S, Imaizumi T, Fukuda I, Furukawa KI
Journal of pharmacological sciences 136 ( 4 ) 257 - 265 2018.4
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Gnetin C, a resveratrol dimer, reduces amyloid-β 1-42 (Aβ42) production and ameliorates Aβ42-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells.
Syota Seino, Takeru Kimoto, Hidemi Yoshida, Kunikazu Tanji, Tomoh Matsumiya, Ryo Hayakari, Kazuhiko Seya, Shogo Kawaguchi, Kazushi Tsuruga, Hiroshi Tanaka, Tadaatsu Imaizumi
Biomedical research (Tokyo, Japan) 39 ( 3 ) 105 - 115 2018.3
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ネパールにおける文字情報サービスに関する支援
瀬谷和彦
ノーマライゼーション: 障害者の福祉 2018.2
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〈一般演題抄録〉ワルファリンによる大動脈弁異所性石灰化促進作用
于 在強, 千代谷 真理, 大徳 和之, 瀬谷 和彦, 古川 賢一, 福田 幾夫
弘前医学 68 ( 2-4 ) 188 2018
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TNF-α induces calcification of cultured human aortic valve interstitial cells obtained from patients with calcific aortic stenosis: involvement of BMP2
Seya Kazuhiko, Yu Zaiqiang, Chiyoya Mari, Daitoku Kazuyuki, Motomura Shigeru, Imaizumi Tadaatsu, Fukuda Ikuo, Furukawa Ken-Ichi
Proceedings for Annual Meeting of The Japanese Pharmacological Society WCP2018 ( 0 ) PO2-3-12 2018
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Ketamine suppresses the proliferation of rat C6 glioma cells.
Hideyuki Niwa, Ken-Ichi Furukawa, Kazuhiko Seya, Kazuki Hirota
ONCOLOGY LETTERS 2017.10
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Simultaneous Measurement of Adenosine 3’,5’-Cyclic Monophosphate and Guanosine 3’,5’-Cyclic Monophosphate in Biological Samples.
Kazuhiko Seya, Shigeru Motomura, Tadaatsu Imaizumi, Ken-Ichi Furukawa
Hirosaki Medical Journal 2017.10
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Ketamine suppresses the proliferation of rat C6 glioma cells.
Niwa H, Furukawa KI, Seya K, Hirota K
Oncology letters 14 ( 4 ) 4911 - 4917 2017.10
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Expression of CCL5 is induced by polyinosinic : polycytidylic acid in cultured hCMEC/D3 human brain microvascular endothelial cells.
Akine Arai, Hidemi Yoshida, Ryo Hayakari, Tomoh Matsumiya, Shogo Kawaguchi, Kazuhiko Seya, Hiroshi Tanak, Tadaatsu Imaizumi
CLINICAL AND EXPERIMENTAL NEUROIMMUNOLOGY 2017.9
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新生仔マウス初代培養心筋細胞の単離培養法
韓沖, 瀬谷和彦, 小潟佳輝, 野崎修平, 米倉学, 村上 学
Hirosaki Medical Journal 2017.2
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Effects of Enflurane on Cardiac Autonomic Nervous Activity in Mice.
Yoshiki Ogata, Manabu Yonekura, Rouichi Yamaki, Chong Han, Tomonori Fujiwara, Kazuhiko Seya, Hidetoshi Niwa, Tetsuya Kushikata, Tadaatsu Imaizumi, Kazuyoshi Hirota, Hirofumi Tomita, Manabu Murakami
Hirosaki Medical Journal 2017.2
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Effects of enflurane on cardiac autonomic nervous activity in mice
Ogata Yoshiki, Hirota Kazuyoshi, Yamaki Rouichi, Han Chong, Fujiwara Tomonori, Seya Kazuhiko, Niwa Hidetoshi, Kushikata Tetsuya, Imaizumi Tadaatsu
Hirosaki Medical Journal 67 ( 2-4 ) 153 - 157 2017
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新生仔マウス初代培養心筋細胞の単離培養法
韓 沖, 瀬谷 和彦, 小潟 佳輝, 野崎 修平, 米倉 学, 村上 学
弘前医学 67 ( 2-4 ) 147 - 152 2017
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〈一般演題抄録〉大動脈弁異所性石灰化のキーレギュレーター： マトリックスグラタンパク質
于 在強, 千代谷 真理, 大徳 和之, 瀬谷 和彦, 古川 賢一, 福田 幾夫
弘前医学 67 ( 2-4 ) 186 2017
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Simultaneous measurement of adenosine 3’,5’-cyclic monophosphate and guanosine 3’,5’-cyclic monophosphate in biological samples.
瀬谷 和彦
Hirosaki Med J 68 52 - 61 2017
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Simultaneous measurement of adenosine 3’,5’-cyclic monophosphate and guanosine 3’,5’-cyclic monophosphate in biological samples
Seya Kazuhiko, Motomura Shigeru, Imaizumi Tadaatsu, Furukawa Ken-Ichi
Hirosaki Medical Journal 68 ( 1 ) 52 - 61 2017
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1-Methyl-2-undecyl-4(1H)-quinolone, a derivative of quinolone alkaloid evocarpine, attenuates high phosphate-induced calcification of human aortic valve interstitial cells by inhibiting phosphate cotransporter PiT-1.
Seya K, Furukawa K, Chiyoya M, Yu Z, Kikuchi H, Daitoku K, Motomura S, Murakami M, Oshima Y, Fukuda I
Journal of pharmacological sciences 131 ( 1 ) 51 - 7 2016.5
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8-Methyltryptanthrin-induced differentiation of P19CL6 embryonal carcinoma cells into spontaneously beating cardiomyocyte-like cells.
Seya K, Yamaya A, Kamachi S, Murakami M, Kitahara H, Kawakami J, Okumura K, Murakami M, Motomura S, Furukawa K
Journal of natural products 77 ( 6 ) 1413 - 9 2014.6
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8‑Methyltryptanthrin-Induced Differentiation of P19CL6 Embryonal Carcinoma Cells into Spontaneously Beating Cardiomyocyte-like Cells
Kazuhiko Seya, Asako Yamaya, Sayuri Kamachi, Mana Murakami, Haruo Kitahara, Jun Kawakami, Ken Okumura, Manabu Murakami, Shigeru Motomura, and Ken-Ichi Furukawa
Journal of Natural Products 77 1413 - 1419 2014.6
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CD34-negative mesenchymal stem-like cells may act as the cellular origin of human aortic valve calcification.
Nomura A, Seya K, Yu Z, Daitoku K, Motomura S, Murakami M, Fukuda I, Furukawa K
Biochemical and biophysical research communications 440 ( 4 ) 780 - 5 2013.11
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CD34-negative mesenchymal stem-like cells may act as the cellular origin of human aortic valve calcification
Anan Nomura, Kazuhiko Seya, Zaiqiang Yu, Kazuyuki Daitoku, Shigeru Motomura,Manabu Murakami, Ikuo Fukuda, Ken-Ichi Furukawa
Biochemical and Biophysical Research Communications 440 ( 780 ) 785 2013.11
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Cytosolic Ca2+-induced apoptosis in rat cardiomyocytes via mitochondrial NO-cGMP-protein kinase G pathway.
Kazuhiko Seya, Kyoichi Ono, Susumu Fujisawa, Ken Okumura, Shigeru Motomura, and Ken-Ichi Furukawa
Journal of Pharmacological and Experimental Therapy 2013.4
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Cytosolic Ca2+-induced apoptosis in rat cardiomyocytes via mitochondrial NO-cGMP-protein kinase G pathway.
Seya K, Ono K, Fujisawa S, Okumura K, Motomura S, Furukawa K
The Journal of pharmacology and experimental therapeutics 344 ( 1 ) 77 - 84 2013.1
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Br-DIF-1 accelerates 1% dimethyl sulfoxide-induced cardiomyocyte differentiation from P19CL6 embryonic carcinoma cells
Kazuhiko Seya他
British Journal of Pharmacology 2012.4
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Tumor Necrosis Factor-{alpha} Accelerates the Calcification of Human Aortic Valve Interstitial Cells Obtained from Patients with Calcific Aortic Valve Stenosis via the BMP2-Dlx5 Pathway.
「Zaiqiang Yu」「Kazuhiko Seya他」
Journal of Pharmacological and Experimental Therapy 2011.4
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Tumor necrosis factor-α accelerates the calcification of human aortic valve interstitial cells obtained from patients with calcific aortic valve stenosis via the BMP2-Dlx5 pathway.
Yu Z, Seya K, Daitoku K, Motomura S, Fukuda I, Furukawa K
The Journal of pharmacology and experimental therapeutics 337 ( 1 ) 16 - 23 2011.4
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Contribution of bone morphogenetic protein-2 to aortic valve calcification in aged rat.
Kazuhiko Seya他
Journal of Pharmacological Sciences 2011.1
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Contribution of Bone Morphogenetic Protein-2 to Aortic Valve Calcification in Aged Rat
Seya Kazuhiko, Yu Zaiqiang, Kanemaru Kouta, Daitoku Kazuyuki, Akemoto Yui, Shibuya Hiroyuki, Fukuda Ikuo, Okumura Ken, Motomura Shigeru, Furukawa Ken-Ichi
Journal of Pharmacological Sciences 115 ( 1 ) 8 - 14 2011
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Opposite effects of two resveratrol (trans-3,5,4'-trihydroxystilbene) tetramers, vitisin A and hopeaphenol, on apoptosis of myocytes isolated from adult rat heart.
Kazuhiko Seya, Kouta Kanemaru, Chiharu Sugimoto, Megumi Suzuki, Teruko Takeo, Shigeru Motomura, Haruo Kitahara, Masatake Niwa, Yoshiteru Oshima, Ken-Ichi Furukawa
Journal of Pharmacology and Experimental Therapy 328 90 - 98 2009.1
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Opposite effects of two resveratrol (trans-3,5,4'-trihydroxystilbene) tetramers, vitisin A and hopeaphenol, on apoptosis of myocytes isolated from adult rat heart.
Seya K, Kanemaru K, Sugimoto C, Suzuki M, Takeo T, Motomura S, Kitahara H, Niwa M, Oshima Y, Furukawa K
The Journal of pharmacology and experimental therapeutics 328 ( 1 ) 90 - 8 2009.1
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Intracellular calcium ion regulates myocardial apoptosis induced by mitochondrial NO-cGMP pathway.
Kazuhiko Seya, Kyoichi Ono, Susumu Fujisawa, Shigeru Motomura, Ken-Ichi Furukawa
Journal of Molecular and Cellular Cardiology 45 S30 - S31 2008.12
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高齢者にはどう聞こえる? (薬局のための 高齢者ケアガイドブック) -- (高齢者の特徴を知ろう)
瀬谷和彦
調剤と情報 14 ( 10 ) 1183 - 1188 2008.9
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Calcification of aortic smooth muscle cells isolated from spontaneously hypertensive rats.
Kouta Kanemaru, Kazuhiko Seya, Izumi Miki, Shigeru Motomura, Ken-Ichi Furukawa
Journal of Pharmacological Sciences 106 280 - 286 2008.2
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Possible role of extracellular nucleotides in ectopic ossification of human spinal ligaments.
Toshikazu Sawada, Masaki Kishiya, Kouta Kanemaru, Kazuhiko Seya, Toru Yokoyama, Kazumasa Ueyama, Shigeru Motomura, Satoshi Toh, Ken-Ichi Furukawa
Journal of Pharmacological Sciences 106 152 - 161 2008.1
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Calcification of Aortic Smooth Muscle Cells Isolated From Spontaneously Hypertensive Rats
Kanemaru Kouta, Seya Kazuhiko, Miki Izumi, Motomura Shigeru, Furukawa Ken-Ichi
Journal of Pharmacological Sciences 106 ( 2 ) 280 - 286 2008
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Possible Role of Extracellular Nucleotides in Ectopic Ossification of Human Spinal Ligaments
Sawada Toshitada, Kishiya Masaki, Kanemaru Kouta, Seya Kazuhiko, Yokoyama Toru, Ueyama Kazumasa, Motomura Shigeru, Toh Satoshi, Furukawa Ken-Ichi
Journal of Pharmacological Sciences 106 ( 1 ) 152 - 161 2008
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Assessment of the effects of L- and N-Type Ca2+ channel blocking drugs using canine isolated blood-perfused papillary muscle preparation.
Kazuyuki Daitoku, Kazuhiko Seya, Ken-Ichi Furukawa, Shigeru Motomura
The Tohoku Journal of Experimental Medicine 212 415 - 422 2007.8
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Cardiac mitochondrial cGMP stimulates cytochrome c release.
Kazuhiko Seya, Shigeru Motomura, Ken-Ichi Furukawa
Clinical Science 112 113 - 121 2007.1
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Cardiac mitochondrial cGMP stimulates cytochrome c release.
Seya K, Motomura S, Furukawa K
Clinical science (London, England : 1979) 112 ( 2 ) 113 - 21 2007.1
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Assessment of the Effects of L- and N-Type Ca2+ Channel Blocking Drugs Using Canine Blood-Perfused Papillary Muscle Preparations
Daitoku Kazuyuki, Seya Kazuhiko, Furukawa Ken-Ichi, Motomura Shigeru
The Tohoku Journal of Experimental Medicine 212 ( 4 ) 415 - 422 2007
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P-28 Scale and Peel of a Garlic as Functional Materials
Kitahara Haruo, Sugimoto Chiharu, Sasaki Narutoshi, Kanemaru Kouta, Togawa Kazuhiro, Handa Tomokazu, Harada Yukio, Sano Teruo, Seya Kazuhiko, Furukawa Ken-ichi, Motomura Shigeru, Ouchi Akihiko
Symposium on the Chemistry of Natural Products, symposium papers 48 ( 0 ) 529 - 534 2006
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Cardiac mitochondrial nitric oxide-cGMP pathway regulates myocardial apoptosis.
Kazuhiko Seya, Ken-Ichi Furukawa, Shigeru Motomura
Mitochondria and Life 2005 110 - 110 2005.12
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Nifedipine enhances cGMP production through the activation of soluble guanylyl cyclase in rat ventricular papillary muscle.
Kazuhiko Seya, Ken-Ichi Furukawa, Kazuhiko Yoshida, Reina Narita, Shigeru Motomura
Journal of Pharmacy and Pharmacology 57 511 - 514 2005.4
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Nifedipine enhances cGMP production through the activation of soluble guanylyl cyclase in rat ventricular papillary muscle.
Seya K, Furukawa K, Yoshida K, Narita R, Motomura S
The Journal of pharmacy and pharmacology 57 ( 4 ) 511 - 4 2005.4
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心筋ミトコンドリア一酸化窒素-cGMP経路によるアポトーシス誘導機構の解明と創薬
瀬谷 和彦, 古川 賢一, 元村 成
日本薬理学雑誌 : FOLIA PHARMACOLOGICA JAPONICA 124 83P - 84P 2004.11
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Role of Corticotropin-Releasing Factor Receptor Type 2βin Urocortin-Induced Vasodilation of Rat Aortas
MIKI Izumi, SEYA Kazuhiko, MOTOMURA Shigeru, FURUKAWA Ken-Ichi
Journal of pharmacological sciences 96 ( 2 ) 170 - 176 2004.10
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Role of Corticotropin Releasing Factor Receptor Type 2beta in Urocortin-Induced Vasodilation of Rat Aortas.
Izumi Miki, Kazuhiko Seya, Shigeru Motomura, Ken-Ichi Furukawa
Journal of Pharmacological Sciences 96 170 - 176 2004.10
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Regulation of cytochrome c release via mitochondrial NO-cGMP pathway in rat cardiac myocytes.
Kazuhiko Seya, Ken-Ichi Furukawa, Shigeru Motomura
Biochimica et Biophysica Acta, Euromit6 Abstract book 69 - 69 2004.7
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For the realization of comfortable medical treatments for hard of hearing and late-deafened people in Japan
Kazuhiko Seya, Tadashi Takaoka
THE PAPERS AND PRESENTATIONS OF THE 7TH IFHOH WORLD CONGRES 2004.7
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Gene expression and functional activity of sodium/calcium exchanger enhanced in vascular smooth muscle cells of spontaneously hypertensive rats.
Satoshi Taniguchi S, Ken-Ichi Furukawa, Satoshi Sasamura, Yasushi Ohizumi, Kazuhiko Seya, Shigeru Motomura
Journal of Cardiovascular Pharmacology 43 629 - 637 2004.5
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Gene expression and functional activity of sodium/calcium exchanger enhanced in vascular smooth muscle cells of spontaneously hypertensive rats.
Taniguchi S, Furukawa K, Sasamura S, Ohizumi Y, Seya K, Motomura S
Journal of cardiovascular pharmacology 43 ( 5 ) 629 - 37 2004.5
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Role of Corticotropin-Releasing Factor Receptor Type 2.BETA. in Urocortin-Induced Vasodilation of Rat Aortas
Miki Izumi, Seya Kazuhiko, Motomura Shigeru, Furukawa Ken-Ichi
Journal of Pharmacological Sciences 96 ( 2 ) 170 - 176 2004
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Endothelium-dependent vasodilatory effect of vitisin C, a novel plant oligostilbene from Vitis Plants (Vitaceae) in rabbit aorta
Kazuhiko Seya, Ken-Ichi Furukawa, Satoshi Taniguchi, Genji Kodzuka, Yoshiteru Oshima, Masatake Niwa, and Shigeru Motomura
Clinical Science 105 73 - 79 2003.7
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Endothelium-dependent vasodilatory effect of vitisin C, a novel plant oligostilbene from Vitis plants (Vitaceae), in rabbit aorta.
Seya K, Furukawa K, Taniguchi S, Kodzuka G, Oshima Y, Niwa M, Motomura S
Clinical science (London, England : 1979) 105 ( 1 ) 73 - 9 2003.7
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Chemiluminescent Assay for Phosphatidylcholine Hydroperoxide.
SEYA Kazuhiko, OHKOHCHI Nobuhiro, SHIBUYA Hiroshi, SATOMI Susumu, MOTOMURA Shigeru
Analytical Sciences 13 ( 2 ) 311 - 314 1997
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Pharmacological properties of pteleprenine, a quinoline alkaloid from <I>Orixa japonica</I> (Rutaceae), in guinea pig ileum and canine left atrium
MURATA Kiyoshi, SEYA Kazuhiko, MIKI Izumi, JUNKE Hisae, MOTOMURA Shigeru, OSHIMA Yoshiteru
Folia Pharmacologica Japonica 110 ( supplement ) 148 - 152 1997