Papers - TAKAHATA Takenori
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Influence of CYP3A5 and ABCB1 polymorphisms on the pharmacokinetics of vincristine in adult patients receiving CHOP therapy
Junichi Nakagawa, Takenori Takahata et al
Cancer Chemother Pharmacol 92 ( 5 ) 391 - 398 2023.5
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アントラサイクリン系抗がん剤の血管外漏出にデクスラゾキサンを使用した4例の検討
高畑武功、佐藤温、照井一史、中川潤一、兵藤塁、粟津朱美、阿保恵美子、蓮井研悟、陳豫、斎藤絢介、佐々木洸太
癌と化学療法 50 ( 4 ) 2023.4
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Newly diagnosed extranodal NK/T-cell lymphoma, nasal type, at the injected left arm after BNT162b2 mRNA COVID-19 vaccination
Takuto Tachita, Takenori Takahata et al
Int J Hematol 118 ( 4 ) 503 - 507 2023.4
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Impact of polymorphisms of pharmacokinetics-related genes and the inflammatory response on the metabolism of voriconazole.
Aiuchi N, Nakagawa J, Sakuraba H, Takahata T, Kamata K, Saito N, Ueno K, Ishiyama M, Yamagata K, Kayaba H, Niioka T
Pharmacology research & perspectives 10 ( 2 ) e00935 2022.3
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Enteral lorlatinib after alectinib as a treatment option in anaplastic lymphoma kinase-positive non-small cell lung cancer with triple problems: carcinomatous meningitis, poor performance status, and dysphagia-a case report.
Sasaki K, Yokota Y, Isojima T, Fujii M, Hasui K, Chen Y, Saito K, Takahata T, Kindaichi S, Sato A
Respirology case reports 9 ( 7 ) e00796 2021.7
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Disseminated carcinomatosis of the bone marrow from rectal cancer: A case report.
Yoshida K, Oyama T, Takahata T, Kudo S, Sato Y, Saito T, Mikami T, Itabashi C, Soma Y, Fukuda S
Clinical case reports 9 ( 3 ) 1483 - 1489 2021.3
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Evaluation for pharmacokinetic exposure of cytotoxic anticancer drugs in elderly patients receiving (R-)CHOP therapy.
Nakagawa J, Takahata T, Hyodo R, Chen Y, Hasui K, Sasaki K, Saito K, Ueno K, Hosoi K, Terui K, Sato A, Niioka T
Scientific reports 11 ( 1 ) 785 2021.1
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多発肝転移を伴う切除不能膵癌に対してFOLFIRINOX療法が著効しConversion Surgeryを施行しえた1例
赤石隆信、高畑武功他
癌と化学療法 46 ( 13 ) 2551 - 2553 2019.12
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A case of celiac disease with type I enteropathy-associated T-cell lymphoma in a Japanese male patient.
Hiraga H, Sakuraba H, Tanaka N, Watanabe R, Akemoto Y, Ota S, Kikuchi H, Sawaya M, Hiraga N, Chinda D, Hanabata N, Mikami T, Shimoyama T, Takahata T, Tanaka M, Fukuda S
Immunological medicine 42 ( 3 ) 142 - 147 2019.9
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胸水細胞診で診断しえたALK陽性未分化大細胞型リンパ腫の1例
小林弘実、小島啓子ら
青森県臨床細胞学会雑誌 36 26 - 29 2019
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<一般演題抄録>多発肝転移を伴う切除不能膵癌に対してFOLFIRINOX療法が著効しconversion surgeryを施行し得た1例
小笠原 宏一, 石戸 圭之輔, 原 裕太郎, 赤石 隆信, 工藤 大輔, 木村 憲央, 米内山 真之介, 陳 豫, 斎藤 絢介, 高畑 武功, 佐藤 温, 袴田 健一
弘前医学 70 ( 1 ) 94 - 94 2019
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癌化学療法施行患者における安全性評価と苦痛度評価の差異に関する患者因子の検討
田中康平、佐藤温、高畑武功、工藤文子、齋藤絢介、陳豫
癌と化学療法 2018.6
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A case of inhibitor-positive acquired von Willebrand syndrome that developed during treatment for cancer of esophagogastric junction
NAKATA Ryoko, KUSHIBIKI Mihoko, OGASAWARA Shu, TAKAHATA Takenori, SAITO Kensuke, SATO Atsushi, SHIMA Midori, KAYABA Hiroyuki
Japanese Journal of Medical Technology 67 ( 3 ) 379 - 383 2018.5
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GemcitabineおよびS-1治療抵抗性膵癌に対するWeekly Paclitaxel療法の後方視的検討
高畑武功、佐藤温、陳豫、齋藤絢介
癌と化学療法 2018.5
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Thymus and activation-regulated chemokine elevation and lymphocytosis in a case of diffuse large B-cell lymphoma
Satoko Minakawa et al
Journal of Cutaneous Immunology and Allergy 2018.4
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Intermittent withdrawal of oxaliplatin for alleviating neurotoxicity during oxaliplatin-based chemotherapy for Japanese patients with inoperable or metastatic colorectal cancer: A phase 2 multicenter study
Shunsuke Kato et al.
Tohoku J Exp Med 2018.4
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食道胃接合部癌の治療中に発症したインヒビター陽性後天性von Willebrand症候群の一例
中田良子ら
医学検査 2018.3
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〈一般演題抄録〉悪性腫瘍後の二次性造血器悪性腫瘍と、造血器悪性腫瘍後の二次性固形がん発症例の検討
間山 恒, 山形 和史, 高畑 武功, 鎌田 耕輔, 陳 豫, 斎藤 絢介, 玉井 佳子, 佐藤 温, 福田 眞作, 髙見 秀樹
弘前医学 68 ( 2-4 ) 190 2018
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A diagnostically challenging case of tuberculosis lymphadenitis
Satoko Minakawa, Takahide Kaneko, Chihiro Hagiwara, Takenori Takahata, Daisuke Sawamura
Dermatologica Sinica 34 217 - 218 2016.4
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肝転移を伴う切除不能胆管癌に対して化学療法が著効した1例
脇屋太一、豊木嘉一、石戸圭之輔、工藤大輔、木村憲央、矢越雄太、石黒敦、高畑武功、佐藤温、袴田健一
癌と化学療法 2013.12
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A change in the number of CCSPpos/SPCpos cells in mouse lung during development, growth, and repair
Ruowen Sun, Qiliang Zhou, Xulu Ye, Takenori Takahata, Atsushi Ishiguro, Hiroshi Kijima, Toshihiro Nukiwa, Yasuo Saijo
Respiratory Investigation 51 229 - 240 2013.4
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mDCF療法が奏効し治癒手術を施行し得た経口摂取不能胃癌の1例
石黒敦、高畑武功ら
癌と化学療法 2012.3
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Methylation of the KEAP1 gene promoter region in human colorectal cancer
Naoyuki Hanada, Takenori Takahata et al
BMC Cancer 2012.3
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Resveratrol selectively induces DNA damage, independent of Smad4 expression, in its efficacy against human head and neck squamous cell carcinoma
Tyagi Alpna, Takenori Takahata et al
Clinical Cancer Research 2011.8
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Plasmablastic lymphomaの1例
廣瀬 千穂, 石黒 敦, 高畑 武功, 伊東 重豪, 西條 康夫
内科 108 ( 1 ) 152 - 155 2011.7
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Sequential irinotecan hydrochloride/S-1 for S-1-resistant gastric cancer: A feasible study
Takenori Takahata et al
Oncolgy Letter 2011.6
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Mesenchymal stromal cells promote tumor growth through the enhancement of neovasculization
Kazuhiro Suzuki et al
Molecular Medicine 2011.4
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A case of gastric cancer with Trousseau syndrome
Shogo Kawaguchi et al
Gan To Kagaku Ryoho 36 ( 2 ) 317 - 320 2009.2
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20-P2-294 ワーファリンとTS-1を含む癌化学療法の併用により相互作用が疑われた症例(がん薬物療法(その他),来るべき時代への道を拓く)
照井 一史, 小田桐 奈央, 細井 一広, 佐藤 淳也, 高畑 武功, 早狩 誠
日本医療薬学会年会講演要旨集 18 ( 0 ) 331 2008.9
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Influence of cancer-related gene polymorphisms on clinicopathological features in colorectal cancer
Gen Yoshiya, Takenori Takahata,et al
Journal of Gastroenterology and Hepatology 23 ( 6 ) 948 - 953 2008.4
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[A case of unresectable advanced gallbladder cancer treated by systemic chemotherapy combined with hepatic arterial infusion].
Ishiguro A, Munakata M, Shitara K, Suzuki K, Takahata T, Itoh J, Sakata Y, Munakata A
Gan to kagaku ryoho. Cancer & chemotherapy 34 ( 7 ) 1127 - 30 2007.7
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[A case of unresectable advanced pancreatic cancer treated by S-1 with concurrent radiotherapy].
Ishiguro A, Munakata M, Shitara K, Suzuki K, Takahata T, Itoh J, Aoki M, Sakata Y, Munakata A
Gan to kagaku ryoho. Cancer & chemotherapy 34 ( 6 ) 937 - 40 2007.6
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Simvastatin inactivates beta 1-integrin and extracellular signal-related kinase signaling and inhibits cell proliferation in head and neck squamous cell carcinoma cells
Ikuko Takeda, Shin-ichiro Maruya, Takashi Shirasaki, Hiroki Mizukami, Takenori Takahata, Jeffrey N. Myers, Seiji Kakehata, Soroku Yagihashi, Hideichi Shinkawa
CANCER SCIENCE 98 ( 6 ) 890 - 899 2007.6
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Chemosensitivity determinantsof CPT-11 in hepatocellular carcinoma cell lines
Takenori Takahata, Keizou Ookawa,et al
Basic Clinlcal Pharmacology &Toxicology 102 39 - 407 2007.4
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高濃度酸素療法が有効であった高齢者腸管嚢腫様気腫症の1例
佐々木聡,高畑武功、他
市立三沢病院医誌 15 ( 1 ) 33 - 36 2007.4
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Abnormality of growth hormone and insulin–like growth factor I axis in advanced cancer patients
Takenori Takahata, Masaki Munakata,
Journal of Clinical Oncolory 25 ( 18S ) 721s 2007.4
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早期胃癌を合併したマントル細胞リンパ腫の1例
花畑憲洋、高畑武功、他
日本消化器内視鏡学会雑誌 49 ( 7 ) 1674 - 1680 2007.4
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S-1単剤および肝動注化学療法が奏功している切除不能進行胆のう癌の1例
石黒敦、高畑武功、他
癌と化学療法 34 ( 7 ) 1127 - 1130 2007.4
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Simvastatin inactivates beta1-integrin and extracellular signal-related kinase signaling and inhibits cell proliferation in head and neck squamous cell carcinoma cells
Ikuko Takeda, Shin-ichiro Maruya,Takenori Takahata,et al
Cancer Science 98 ( 6 ) 890 - 899 2007.4
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Pharmacokinetics of low-dose nedaplatin and validation of AUC prediction in pati ents with non-small-cell lung carcinoma
Takenori Niioka, Tsukasa Uno,Takenori Takahata,et al
Cancer Chemotherapy and Pharmacology 59 ( 5 ) 575 - 580 2007.4
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Pharmacokinetics of low-dose nedaplatin and validation of AUC prediction in patients with non-small-cell lung carcinoma
Takenori Niioka, Tsukasa Uno, Norio Yasui-Furukori, Takenori Takahata, Mikiko Shimizu, Kazunobu Sugawara, Tomonori Tateishi
CANCER CHEMOTHERAPY AND PHARMACOLOGY 59 ( 5 ) 575 - 580 2007.4
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A CASE OF MANTLE CELL LYMPHOMA WITH EARLY GASTRIC CANCER
HANABATA Norihiro, MIKAMI Tatsuya, FUKUDA Shinsaku, NISHIYA Daisuke, SASAKI Satoshi, TAKAHATA Takenori, ITOH Jugoh, SASAKI Yoshihiro, KIJIMA Hiroshi, MUNAKATA Akihiro
GASTROENTEROLOGICAL ENDOSCOPY 49 ( 7 ) 1674 - 1680 2007
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The influence of methylated p15INK4b and p16INK4a genes on clinicopathological features in colorectal cancer
Atsushi Ishiguro, Takenori Takahata et al
Journal of Gastroenterology and Hepatology 21 ( 8 ) 1334 - 1339 2006.4
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経過中にmultiple lymphomatous polyposisを大腸に認めた悪性リンパ腫の一例
吉谷元、鈴木一広、高畑武功、他
青森県立中央病院医誌 51 ( 4 ) 126 - 131 2006.4
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日本人高齢者におけるCYP2C19変異遺伝子頻度とオメプラゾール薬物動態を指標とした生体内CYP2C19活性の検討
石澤幸男、高畑武功、他
臨床薬理の進歩 ( 27 ) 82 - 87 2006.4
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Sensitive determination of omeprazole and its two main metabolites in human plasma by column-switching high-performance liquid chromatography: application to pharmacokinetic study in relation to CYP2C19 genotype
Mikiko Shimizu,Takenori Takahata et al
Journal of Chromatography B Amalyt Technol Biomed Life Science 832 ( 2 ) 241 - 218 2006.4
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Lack of significant effect of grapefruit juice on the pharmacokinetics of lansoprazole and its metabolites in subjects with different CYP2C19 genotypes.
Uno T, Yasui-Furukori N, Takahata T, Sugawara K, Tateishi T
Journal of clinical pharmacology 45 ( 6 ) 690 - 4 2005.6
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S-1/CDDP併用化学療法が奏功した進行低分化型胃癌の1例
佐々木聡、高畑武功,他
青森県立中央病院医誌 50 ( 4 ) 137 - 141 2005.4
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露出腫瘤型乳頭癌の診断にて切除後、病理学的検索にて膵頭部癌と診断された1例の考察
加藤幸三、須藤晃司、高畑武功 他
弘前市立病院医誌 14 ( 1 ) 19 - 24 2005.4
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合流部結石の2症例
木村由佳、須藤晃司,高畑武功 他
弘前市立病院医誌 14 ( 1 ) 25 - 29 2005.4
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C型慢性肝炎にみられたhypovascularな脂肪原性肝腫瘍の1例
高畑武功、須藤晃司,他
弘前市立病院医誌 14 ( 1 ) 35 - 40 2005.4
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The effect of aging on the relationship between the cytochrome P450 2C19 genotype and omeprazole pharmacokinetics
Yukio Ishizawa, Norio Yasui-Furukori, Takenori Takahata et al
Clin Pharmacokinet 44 ( 11 ) 1179 - 1189 2005.4
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Influence of hepatic impairment on the pharmacokinetics and pharmacodynamics of landiolol hydrochloride, an ultra-short-acting beta1-blocker
Takenori Takahata et al
Drugs RD 6(6) 385 - 394 2005.4
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Lack of significant effect of grapefruit juice on the pharmacokinetics of lansoprazole and itsmetabolites in subjects with different CYP2C19 genotypes
Tsukasa Uno, Norio Yasui-Furukori, Takenori Takahata et al
Journal of Clinical Pharmacology 45 690 - 694 2005.4
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Determination of lansoprazole and two of its metabolites by liquid-liquid extraction and automated column-switching high-performance liquid chromatography: application to measuring CYP2C19 activity
Tsukasa Uno, Norio Yasui-Furukori, Takenori Takahata at al
Journal of Chromatography B 816 309 - 314 2005.4
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Effects of clarithromycin on lansoprazole pharmacokinetics between CYP2C19 genotypes
Masato Saito, Norio Yasui-Furukori, Tsukasa Uno, Takenori Takahata et al
British Journal of Clinical Pharmacology 59 302 - 309 2005.4
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Effects of clarithromycin on lansoprazole pharmacokinetics between CYP2C19 genotypes
M Saito, N Yasui-Furukori, T Uno, T Takahata, K Sugawara, A Munakata, T Tateishi
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 59 ( 3 ) 302 - 309 2005.3
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The effect of aging on the relationship between the cytochrome P450 2C19 genotype and omeprazole pharmacokinetics.
Ishizawa Y, Yasui-Furukori N, Takahata T, Sasaki M, Tateishi T
Clinical pharmacokinetics 44 ( 11 ) 1179 - 89 2005
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Effects of fluvoxamine on lansoprazole pharmacokinetics in relation to CYP2C19 genotypes
N Yasui-Furukori, M Saito, T Uno, T Takahata, K Sugawara, T Tateishi
JOURNAL OF CLINICAL PHARMACOLOGY 44 ( 11 ) 1223 - 1229 2004.11
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Effects of various factors on steady-state plasma concentrations of risperidone and 9-hydroxyrisperidone: lack of impact of MDR-1 genotypes
N Yasui-Furukori, K Mihara, T Takahata, A Suzuki, T Nakagami, R De Vries, T Tateishi, T Kondo, S Kaneko
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 57 ( 5 ) 569 - 575 2004.5
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Weekly paclitaxel and nedaplatin with concurrent radiotherapy for locally advanced non-small-cell lung cancer: a phase I/II study
Yukihiro Hasegawa, Shingo Takanashi,Takenori Takahata et al
Japanese Journal of Clinical Oncology 34 647 - 653 2004.4
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Phase I study of 24-hr continuous hepatic arterial infusion of irinotecan (24hr HAI CPT-11) for patients with hepatocellular carcinoma (HCC)
Koji Suto, Yuh Sakata, Takenori Takahata et al
Annals of Oncology 15 106 2004.4
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Liquid chromatographic determination of fexofenadine in human plasma with fluorescence detection
Tsukasa Uno, Norio Yasui-Furukori, Takenori Takahata et al
Journal of Pharmaceutical Biomedical Analysis 35 937 - 942 2004.4
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Effect of fluvoxamine on lansoprazole pharmacokinetics in relation to CYP2C19 genotypes
Norio Yasui-Furukori, Masato Saito, Takenori Takahata et al
Journal of Clinical Pharmacology 44 1223 - 1229 2004.4
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Effects of various factors on steady-state plasma concentrations of risperidone and 9-hydroxyrisperidone: lack of impact of MDR-1 genotypes
Norio Yasui-Furukori, Kazuo Mihara, Takenori Takahata et al
British Journal of Clinical Pharmacology 57 569 - 575 2004.4
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Fexofenadine does not affect omeprazple pharmacokinetics: both are putative P-glycoprotein substrates
Takenori Takahata et al
Basic and Clinical Pharmacology and Toxicology 94 252 - 256 2004.4
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Inhibition of 3T3-L1 adipocyte differentiation by 6-ethoxyzolamide: repressed peroxysome proliferator-activated receptor gamma mRNA and enhanced CCAAT/enhancer binding protein beta mRNA levels
Takenori Takahata et al
Biochemical Pharmacology 67 1667 - 1675 2004.4
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Different inhibitory effect of fluvoxamine on omeprazole metabolism between CYP2C19 genotypes.
Yasui-Furukori N, Takahata T, Nakagami T, Yoshiya G, Inoue Y, Kaneko S, Tateishi T
British journal of clinical pharmacology 57 ( 4 ) 487 - 94 2004.4
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CYP2C19遺伝子型別にみたオメプラゾールの代謝に与えるフルボキサミンの影響
古郡 規雄, 高畑 武功, 中神 卓, 兼子 直, 立石 智則
臨床薬理 35 ( 1 ) 223S - 223S 2004
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Lansoprazoleの薬物相互作用とCYP2C19遺伝子多型の関連性の検討
齋藤 正人, 古郡 規雄, 宇野 司, 高畑 武功, 菅原 和信, 棟方 昭博, 立石 智則
臨床薬理 35 ( 1 ) 222S - 222S 2004
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健康成人を対照とした肝硬変患者における塩酸ランジオロール臨床薬理試験
高畑 武功, 古郡 規雄, 立石 智則, 須藤 晃司, 須藤 俊之, 棟方 昭博
臨床薬理 35 ( 1 ) 191S - 191S 2004
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Nucleotide changes in the translated region of SCN5A from Japanese patients with Brugada syndrome and control subjects.
Takahata T, Yasui-Furukori N, Sasaki S, Igarashi T, Okumura K, Munakata A, Tateishi T
Life sciences 72 ( 21 ) 2391 - 9 2003.4
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CYP2C19 mutation frequency in elderly subjects living in a sparsely populated area of Shimokita peninsula (jointly worked)
Yukio Ishizawa, Takenori Takahata et al
Hirosaki Medical Journal 55 18 - 22 2003.4
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Time effects of food intake on the pharmacokinetics and pharmacodynamics of quazepam
N Yasui-Furukori, T Takahata, T Kondo, K Mihara, S Kaneko, T Tateishi
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 55 ( 4 ) 382 - 388 2003.4
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CYP2C19 mutation frequency in elderly subjects living in a sparsely populated area of Shimokita peninsula
Ishizawa Yukio, Takahata Takenori, Yasui-Furukori Norio, Saito Masato, Sasaki Mutsuo, Tateishi Tomonori
Hirosaki Medical Journal 55 ( 1 ) 18 - 22 2003
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クアゼパムの吸収過程における食事摂取時間と食事中の脂肪量の影響について
古郡 規雄, 高畑 武功, 近藤 毅, 三原 一雄, 小野 真吾, 兼子 直, 立石 智則
臨床薬理 34 ( 2 ) 293S - 294S 2003
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Effect of dietary fat content in meals on pharmacokinetics of quazepam.
Yasui-Furukori N, Kondo T, Takahata T, Mihara K, Ono S, Kaneko S, Tateishi T
Journal of clinical pharmacology 42 ( 12 ) 1335 - 40 2002.12
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Determination of donepezil, an acetylcholinesterase inhibitor, in human plasma by high-performance liquid chromatography with ultraviolet absorbance detection
N Yasui-Furukori, R Furuya, T Takahata, T Tateishi
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 768 ( 2 ) 261 - 265 2002.3
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Carbamazepine併用によってNilvadipineの降圧効果の減弱をみた症例
古郡 規雄, 高畑 武功, 立石 智則
臨床薬理 33 ( 1 ) 143S - 144S 2002
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Metabolism of glucocorticoid hormone by macrophage migration inhibitory factor
M Hayakari, J Kimura, T Kumano, T Takahata, S Suzuki, K Satoh, S Tsuchida
NEW DIRECTIONS FOR CELLULAR AND ORGAN TRANSPLANTATION 1210 31 - 35 2000
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Pi-class glutathione transferase expression and function in mouse neoplasia
S Tsuchida, H Nakano, K Ookawa, Kakizaki, I, Hatayama, I, T Kumano, T Takahata, J Kimura, M Hayakari, K Satoh
MOLECULAR MEDICINE: NOVEL FINDINGS OF GENE DIAGNOSIS, REGULATION OF GENE EXPRESSION, AND GENE THERAPY 1172 113 - 122 1999
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Identification of Glutathione S-Transferase p-1 as the Class Pi Form Dominantly Expressed in Mouse Hepatic Adenomas 共著
Ookawa K, Nakano H, Kakizaki I, Hatayama I, Kajihara-Kano H, Kimura J, Hayakari M, Takahata T, Satoh K, Tsuchida S
Jpn. Cancer Res. 89 ( 6 ) 641 - 648 1998
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A case of nodular transformation of the liver with idiopathic portal hypertension.
TAKAHATA Takenori, SASAKI Yoshio, HIRANO Kazuhito, ISHIGURO Yoh, TAKAHASHI Toshiyuki, SUTO Koji, SUTO Toshiyuki, MUNAKATA Akihiro, YODONO Hiraku, TANAKA Masanori, KUDO Hajime, KAGE Masayoshi
Nippon Shokakibyo Gakkai Zasshi 94 ( 9 ) 615 - 621 1997