日本小児血液学会

難治性ランゲルハンス細胞組織球症に対するvemurafenib治療症例における測定可能残存病変

工藤 耕, 金崎 里香, 小野 林太郎, 坂本 謙一, 辻本 信一, 市川 貴之, 長谷川 大一郎, 渡邉 健一郎, 田中 龍彦, 土岐 力, 伊藤 悦朗, 加藤 元博, 塩田 曜子

日本血液学会学術集会   86回   O1 - 5   2024.10

結節性硬化症11例における原因遺伝子変異の検討

山本 洋平, 山本 達也, 工藤 耕, 土岐 力, 金崎 里香, 伊東 竜也, 品川 友江, 浅利 有紗, 梅津 英典, 伊藤 悦朗, 照井 君典

弘前医学   75 ( 1 )   81 - 81   2024.10

ダウン症候群の骨髄性白血病における体細胞変異の全体像とその臨床的影響

佐藤 知彦, 吉田 健一, 土岐 力, 金崎 理香, 照井 君典, 佐伯 龍之介, 小島 正美, 越智 陽太郎, 上地 珠代, 剣持 直哉, 田中 司朗, 松林 潤, 工藤 耕, 湯沢 健太郎, 高橋 佑果, 村松 秀城, 長谷川 大輔, 出口 隆生, 松尾 英将, 足立 壯一, 林 泰秀, 多賀 崇, 齋藤 明子, 堀部 敬三, 渡邉 健一郎, 富澤 大輔, 宮野 悟, 高橋 智, 小川 誠司, 伊藤 悦朗

日本血液学会学術集会   86回   O1 - 6   2024.10

Mutational analysis by targeted sequencing in 11 cases of tuberous sclerosis

Yamamoto Yohei, Yamamoto Tatsuya, Kudo Ko, Toki Tsutomu, Kanezaki Rika, Ito Tatsuya, Shinagawa Tomoe, Asari Arisa, Umetsu Hidenori, Fujita Hiroshi, Ito Etsuro, Terui Kiminori

Hirosaki Medical Journal   74 ( 1-4 )   17 - 27   2024.3

Landscape of driver mutations and their clinical effects on Down syndrome-related myeloid neoplasms

Tomohiko Sato, Kenichi Yoshida, Tsutomu Toki, Rika Kanezaki, Kiminori Terui, Ryunosuke Saiki, Masami Ojima, Yotaro Ochi, Seiya Mizuno, Masaharu Yoshihara, Tamayo Uechi, Naoya Kenmochi, Shiro Tanaka, Jun Matsubayashi, Kenta Kisai, Ko Kudo, Kentaro Yuzawa, Yuka Takahashi, Tatsuhiko Tanaka, Yohei Yamamoto, Akie Kobayashi, Takuya Kamio, Shinya Sasaki, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Hideki Muramatsu, Asahito Hama, Daisuke Hasegawa, Atsushi Sato, Katsuyoshi Koh, Shuhei Karakawa, Masao Kobayashi, Junichi Hara, Yuichi Taneyama, Chihaya Imai, Daiichiro Hasegawa, Naoto Fujita, Masahiro Yoshitomi, Shotaro Iwamoto, Genki Yamato, Satoshi Saida, Nobutaka Kiyokawa, Takao Deguchi, Masafumi Ito, Hidemasa Matsuo, Souichi Adachi, Yasuhide Hayashi, Takashi Taga, Akiko Moriya Saito, Keizo Horibe, Kenichiro Watanabe, Daisuke Tomizawa, Satoru Miyano, Satoru Takahashi, Seishi Ogawa, Etsuro Ito

Blood Journal   143 ( 25 )   2627 - 2643   2024.3

Transient erythroblastopenia due to a <i>GATA1</i> variant in an infant female

Motoi Yamashita, Takahiro Tomoda, Ami Mizuo, Takeshi Isoda, Makiko Egawa, Masayuki Yoshida, Tsutomu Toki, Ko Kudo, Kiminori Terui, Etsuro Ito, Tomohiro Morio, Masatoshi Takagi

Pediatric Blood &amp; Cancer   71 ( 3 )   e30834   2024.3

Antileukemic effect of azacitidine, a DNA methyltransferase inhibitor, on cell lines of myeloid leukemia associated with Down syndrome.

Tatsuhiko Tanaka, Ko Kudo, Rika Kanezaki, Kentaro Yuzawa, Tsutomu Toki, Ryo Okuse, Akie Kobayashi, Tomohiko Sato, Takuya Kamio, Kiminori Terui, Etsuro Ito

Experimental hematology   132   104179 - 104179   2024.2

Early-onset Marfan syndrome with a novel missense mutation: A case report.

Kana Soma, Yosuke Kitagawa, Tsutomu Toki, Fumitake Miura, Jun Shimada, Tomohiko Sato, Ko Kudo, Katsuki Otani, Toru Takahashi, Kiminori Terui

Journal of cardiology cases   27 ( 6 )   283 - 286   2023.6

グルココルチコイド受容体point mutationによるグルココルチコイド抵抗症二家系の解析

高安 忍, 浅利 ゆう子, 崎原 哲, 須田 俊宏, 臼谷 真理, 中田 有紀, 綿貫 裕, 土岐 力, 金崎 里香, 蔭山 和則, 大門 眞

日本内分泌学会雑誌   99 ( 1 )   301 - 301   2023.5

グルココルチコイド受容体point mutationによるグルココルチコイド抵抗症二家系の解析

高安 忍, 浅利 ゆう子, 崎原 哲, 須田 俊宏, 臼谷 真理, 中田 有紀, 綿貫 裕, 土岐 力, 金崎 里香, 蔭山 和則, 大門 眞

日本内分泌学会雑誌   99 ( 1 )   301 - 301   2023.5

次世代シークエンサーを用いた結節性硬化症の遺伝学的検討

山本 洋平, 山本 達也, 土岐 力, 奥瀬 諒, 伊東 竜也, 梅津 英典, 工藤 耕, 伊藤 悦朗, 照井 君典, 品川 友江, 浅利 有紗, 藤田 浩史

日本小児科学会雑誌   127 ( 4 )   664 - 664   2023.4

Dyserythropoietic anaemia with an intronic GATA1 splicing mutation in patients suspected to have Diamond-Blackfan anaemia

Akie Kobayashi, Ryusei Ohtaka, Tsutomu Toki, Junichi Hara, Hideki Muramatsu, Rika Kanezaki, Yuka Takahashi, Tomohiko Sato, Takuya Kamio, Ko Kudo, Shinya Sasaki, Taro Yoshida, Taiju Utsugisawa, Hitoshi Kanno, Kenichi Yoshida, Yasuhito Nannya, Yoshiyuki Takahashi, Seiji Kojima, Satoru Miyano, Seishi Ogawa, Kiminori Terui, Etsuro Ito

eJHaem   3   163 - 167   2022.12

Mechanism of KIT gene regulation by GATA1 lacking the N-terminal domain in Down syndrome-related myeloid disorders.

Rika Kanezaki, Tsutomu Toki, Kiminori Terui, Tomohiko Sato, Akie Kobayashi, Ko Kudo, Takuya Kamio, Shinya Sasaki, Koji Kawaguchi, Kenichiro Watanabe, Etsuro Ito

Scientific reports   12 ( 1 )   20587 - 20587   2022.11

NTRK1遺伝子変異を認めた先天性無痛無汗症の1例

黒瀧 奎吾, 梅津 英典, 伊東 竜也, 八木 弘子, 山本 達也, 土岐 力, 照井 君典, 町田 佳織

日本小児科学会雑誌   126 ( 4 )   734 - 735   2022.4

BRAFV600E-positive cells as molecular markers of bone marrow disease in pediatric Langerhans cell histiocytosis.

Kudo K, Toki T, Kanezaki R, Tanaka T, Kamio T, Sato T, Sasaki S, Imamura M, Imai C, Ando K, Kakuda H, Doi T, Kawaguchi H, Irie M, Sasahara Y, Tamura A, Hasegawa D, Itakura Y, Watanabe K, Sakamoto K, Shioda Y, Kato M, Kudo K, Fukano R, Sato A, Yagasaki H, Kanegane H, Kato I, Umeda K, Adachi S, Kataoka T, Kurose A, Nakazawa A, Terui K, Ito E

Haematologica   - ( 7 )   1719 - 1725   2022.3

Childhood acute myeloid leukemia with 5q deletion and HNRNPH1-MLLT10 fusion: the first case report.

Ko Kudo, Yasuo Kubota, Tsutomu Toki, Rika Kanezaki, Akie Kobayashi, Tomohiko Sato, Takuya Kamio, Shinya Sasaki, Norio Shiba, Daisuke Tomizawa, Souichi Adachi, Kenichi Yoshida, Seishi Ogawa, Masafumi Seki, Junko Takita, Etsuro Ito, Kiminori Terui

Blood advances   6 ( 10 )   3162 - 3166   2022.2

A Case of Congenital Leukemia With MYB-GATA1 Fusion Gene in a Female Patient.

Shuichi Ozono, Shoichiro Yano, Saori Oishi, Miho Mitsuo, Shinichiro Nakagawa, Tsutomu Toki, Kiminori Terui, Etsuro Ito

Journal of pediatric hematology/oncology   44 ( 1 )   e250 - e252   2022.1

Erythromelalgia presenting as recurrent purpura and hypogammaglobulinemia: A case report

Karasawa Takao, Hashimoto Shun, Sato Riko, Fujita Masashi, Aizawa Tomomi, Tsugawa Koji, Toki Tsutomu, Kanezaki Rika, Sato Tomohiko, Kudo Ko, Terui Kiminori, Tanaka Hiroshi

Hirosaki Medical Journal   72 ( 1-4 )   80 - 83   2022

Ribosomal protein L5 facilitates rDNA-bundled condensate and nucleolar assembly

伊藤 由馬, 徳永 万喜洋, 原口 徳子, 粟津 暁紀, 落合 博, 土岐 力, 伊藤 悦朗, 中尾 光善, 斉藤 典子

Life Sci Alliance   5 ( 7 )   2022

Correction to: Post-induction MRD by FCM and GATA1-PCR are significant prognostic factors for myeloid leukemia of Down syndrome (Leukemia, (2021), 35, 9, (2508-2516), 10.1038/s41375-021-01157-w)

Takashi Taga, Shiro Tanaka, Daisuke Hasegawa, Kiminori Terui, Tsutomu Toki, Shotaro Iwamoto, Hidefumi Hiramatsu, Takako Miyamura, Yoshiko Hashii, Hiroshi Moritake, Hideki Nakayama, Hiroyuki Takahashi, Akira Shimada, Tomohiko Taki, Etsuro Ito, Asahito Hama, Masafumi Ito, Katsuyoshi Koh, Daiichiro Hasegawa, Akiko M. Saito, Souichi Adachi, Daisuke Tomizawa

Leukemia   35 ( 12 )   3622 - 3624   2021.12

Association of Multiple Gene Polymorphisms Including Homozygous NUDT15 R139C With Thiopurine Intolerance During the Treatment of Acute Lymphoblastic Leukemia.

Kudo K, Sato T, Takahashi Y, Yuzawa K, Kobayashi A, Kamio T, Sasaki S, Shimada J, Otani K, Tusjimoto S, Kato M, Toki T, Terui K, Ito E

Journal of pediatric hematology/oncology   43 ( 8 )   e1173 - e1176   2021.11

Post-induction MRD by FCM and GATA1-PCR are significant prognostic factors for myeloid leukemia of Down syndrome.

Takashi Taga, Shiro Tanaka, Daisuke Hasegawa, Kiminori Terui, Tsutomu Toki, Shotaro Iwamoto, Hidefumi Hiramatsu, Takako Miyamura, Yoshiko Hashii, Hiroshi Moritake, Hideki Nakayama, Hiroyuki Takahashi, Akira Shimada, Tomohiko Taki, Etsuro Ito, Asahito Hama, Masafumi Ito, Katsuyoshi Koh, Daiichiro Hasegawa, Akiko M Saito, Souichi Adachi, Daisuke Tomizawa

Leukemia   35 ( 9 )   2508 - 2516   2021.9

Usefulness of functional splicing analysis to confirm precise disease pathogenesis in Diamond-Blackfan anemia caused by intronic variants in RPS19.

Satoru Takafuji, Takeshi Mori, Noriyuki Nishimura, Nobuyuki Yamamoto, Suguru Uemura, Kandai Nozu, Kiminori Terui, Tsutomu Toki, Etsuro Ito, Hideki Muramatsu, Yoshiyuki Takahashi, Masafumi Matsuo, Tomohiko Yamamura, Kazumoto Iijima

Pediatric hematology and oncology   38 ( 6 )   515 - 527   2021.9

BRAFV600E-positive precursors as molecular markers of bone marrow disease in LCH(和訳中)

工藤 耕, 土岐 力, 金崎 里香, 小林 明恵, 佐藤 知彦, 神尾 卓哉, 佐々木 伸也, 今村 勝, 今井 千速, 安藤 久美子, 角田 治美, 土居 岳彦, 川口 浩史, 入江 正寛, 笹原 洋二, 田村 彰広, 長谷川 大一郎, 板倉 陽介, 渡邉 健一郎, 深野 玲司, 坂本 謙一, 塩田 曜子, 加藤 元博, 工藤 寿子, 金兼 弘和, 伊藤 悦朗, 照井 君典

日本血液学会学術集会   83回   OS2 - 2   2021.9

Predictive factors for the development of leukemia in patients with transient abnormal myelopoiesis and Down syndrome.

Genki Yamato, Takao Deguchi, Kiminori Terui, Tsutomu Toki, Tomoyuki Watanabe, Takahiro Imaizumi, Asahito Hama, Shotaro Iwamoto, Daisuke Hasegawa, Takahiro Ueda, Tomoko Yokosuka, Shiro Tanaka, Ryu Yanagisawa, Katsuyoshi Koh, Akiko M Saito, Keizo Horibe, Yasuhide Hayashi, Souichi Adachi, Shuki Mizutani, Takashi Taga, Etsuro Ito, Kenichiro Watanabe, Hideki Muramatsu

Leukemia   35 ( 5 )   1480 - 1484   2021.5

Reduced-intensity conditioning is effective for hematopoietic stem cell transplantation in young pediatric patients with Diamond-Blackfan anemia.

Shun Koyamaishi, Takuya Kamio, Akie Kobayashi, Tomohiko Sato, Ko Kudo, Shinya Sasaki, Rika Kanezaki, Daiichiro Hasegawa, Hideki Muramatsu, Yoshiyuki Takahashi, Yoji Sasahara, Hidefumi Hiramatsu, Harumi Kakuda, Miyuki Tanaka, Masataka Ishimura, Masanori Nishi, Akira Ishiguro, Hiromasa Yabe, Takeo Sarashina, Masaki Yamamoto, Yuki Yuza, Nobuyuki Hyakuna, Kenichi Yoshida, Hitoshi Kanno, Shouichi Ohga, Akira Ohara, Seiji Kojima, Satoru Miyano, Seishi Ogawa, Tsutomu Toki, Kiminori Terui, Etsuro Ito

Bone marrow transplantation   56 ( 5 )   1013 - 1020   2021.5

Correction: Reduced-intensity conditioning is effective for hematopoietic stem cell transplantation in young pediatric patients with Diamond-Blackfan anemia (Bone Marrow Transplantation, (2021), 56, 5, (1013-1020), 10.1038/s41409-020-01056-1)

Shun Koyamaishi, Takuya Kamio, Akie Kobayashi, Tomohiko Sato, Ko Kudo, Shinya Sasaki, Rika Kanezaki, Daiichiro Hasegawa, Hideki Muramatsu, Yoshiyuki Takahashi, Yoji Sasahara, Hidefumi Hiramatsu, Harumi Kakuda, Miyuki Tanaka, Masataka Ishimura, Masanori Nishi, Akira Ishiguro, Hiromasa Yabe, Takeo Sarashina, Masaki Yamamoto, Yuki Yuza, Nobuyuki Hyakuna, Kenichi Yoshida, Hitoshi Kanno, Shouichi Ohga, Akira Ohara, Seiji Kojima, Satoru Miyano, Seishi Ogawa, Tsutomu Toki, Kiminori Terui, Etsuro Ito

Bone Marrow Transplantation   56 ( 5 )   1218 - 1219   2021.5

Correction: Reduced-intensity conditioning is effective for hematopoietic stem cell transplantation in young pediatric patients with Diamond-Blackfan anemia.

Shun Koyamaishi, Takuya Kamio, Akie Kobayashi, Tomohiko Sato, Ko Kudo, Shinya Sasaki, Rika Kanezaki, Daiichiro Hasegawa, Hideki Muramatsu, Yoshiyuki Takahashi, Yoji Sasahara, Hidefumi Hiramatsu, Harumi Kakuda, Miyuki Tanaka, Masataka Ishimura, Masanori Nishi, Akira Ishiguro, Hiromasa Yabe, Takeo Sarashina, Masaki Yamamoto, Yuki Yuza, Nobuyuki Hyakuna, Kenichi Yoshida, Hitoshi Kanno, Shouichi Ohga, Akira Ohara, Seiji Kojima, Satoru Miyano, Seishi Ogawa, Tsutomu Toki, Kiminori Terui, Etsuro Ito

Bone marrow transplantation   56 ( 5 )   1218 - 1219   2021.5

Down syndrome-related transient abnormal myelopoiesis is attributed to a specific erythro-megakaryocytic subpopulation with GATA1 mutation.

Yoko Nishinaka-Arai, Akira Niwa, Shiori Matsuo, Yasuhiro Kazuki, Yuwna Yakura, Takehiko Hiroma, Tsutomu Toki, Tetsushi Sakuma, Takashi Yamamoto, Etsuro Ito, Mitsuo Oshimura, Tatsutoshi Nakahata, Megumu K Saito

Haematologica   106 ( 2 )   635 - 640   2021.2

New insights into inherited bone marrow failure syndrome

ITO Etsuro, TOKI Tsutomu, KAMIO Takuya, TERUI Kiminori

Rinsho Ketsueki   62 ( 10 )   1455 - 1464   2021

Enzymatic Changes in Red Blood Cells of Diamond-Blackfan Anemia

Utsugisawa Taiju, Uchiyama Toshitaka, Toki Tsutomu, Shimojima-Yamamoto Keiko, Ohga Shouichi, Ito Etsuro, Kanno Hitoshi

The Tohoku Journal of Experimental Medicine   255 ( 1 )   49 - 55   2021

Outcome of colorectal cancer in Diamond-Blackfan syndrome with a ribosomal protein S19 mutation.

Kazuya Kimura, Kazuhiro Shimazu, Tsutomu Toki et al.

Clinical journal of gastroenterology   13 ( 6 )   1173 - 1177   2020.12

Clinical, cytogenetic, and molecular analyses of 17 neonates with transient abnormal myelopoiesis and nonconstitutional trisomy 21.

Kentaro Yuzawa, Kiminori Terui, Tsutomu Toki, Rika Kanezaki, Akie Kobayashi, Tomohiko Sato, Takuya Kamio, Ko Kudo, Shinya Sasaki, Mikiya Endo, Shuichi Ozono, Keiko Nomura, Etsuro Ito

Pediatric blood & cancer   67 ( 4 )   e28188   2020.2

BRAFV600E-Positive Precursors as Molecular Markers of Bone Marrow Involvement in Pediatric Langerhans Cell Histiocytosis

Kudo Ko, Kanezaki Rika, Masaru Imamura, Imai Chihaya, Irie Masahiro, Sasahara Yoji, Ando Kumiko, Kakuda Harumi, Doi Takehiko, Kawaguchi Hiroshi, Kudo Kazuko, Kanegane Hirokazu, Kobayashi Akie, Sato Tomohiko, Kamio Takuya, Sasaki Shinya, Terui Kiminori, Toki Tsutomu, Ito Etsuro

PEDIATRIC BLOOD & CANCER   66   S47   2019.12

Clinical and Molecular Cytogenetic Analysis of 15 Mosaic/Non-Down Syndrome Neonates With Transient Abnormal Myelopoiesis

Yuzawa Kentaro, Terui Kimnori, Toki Tsutomu, Kanezaki Rika, Kobayashi Akie, Sato Tomohiko, Kamio Takuya, Kudo Ko, Sasaki Shinya, Endo Mikiya, Ozono Shuichi, Ito Etsuro

PEDIATRIC BLOOD & CANCER   66   S35   2019.12

HNRNPH1-MLLT10 Fusion in Childhood Acute Myeloid Leukemia with 5q Abnormalities; A Case Report

Kudo Ko, Kobayashi Akie, Sato Tomohiko, Kamio Takuya, Sasaki Shinya, Kanezaki Rika, Toki Tsutomu, Terui Kiminori, Ito Etsuro

PEDIATRIC BLOOD & CANCER   66   S20 - S21   2019.12

小児における前駆B細胞急性リンパ芽球性白血病の再発例を対象とした網羅的遺伝子解析(Comprehensive genetic analyses of relapsed B-cell precursor acute lymphoblastic leukemia in children)

Kubo Kaori, Kudo Ko, Toki Tsutomu, Kanezaki Rika, Ikeda Fumika, Ito Tatsuya, Kobayashi Akie, Sato Tomohiko, Kamio Takuya, Sasaki Shinya, Terui Kiminori, Ito Etsuro

弘前医学   70 ( 1 )   13 - 23   2019.11

Highly sensitive detection of GATA1 mutations in patients with myeloid leukemia associated with Down syndrome by combining Sanger and targeted next generation sequencing.

Terui K, Toki T, Taga T, Iwamoto S, Miyamura T, Hasegawa D, Moritake H, Hama A, Nakashima K, Kanezaki R, Kudo K, Saito AM, Horibe K, Adachi S, Tomizawa D, Ito E

Genes, chromosomes & cancer   59 ( 3 )   160 - 167   2019.10

Integrated genetic and epigenetic analysis revealed heterogeneity of acute lymphoblastic leukemia in Down syndrome.

Yasuo Kubota, Kumiko Uryu, Tatsuya Ito, Masafumi Seki, Tomoko Kawai, Tomoya Isobe, Tadayuki Kumagai, Tsutomu Toki, Kenichi Yoshida, Hiromichi Suzuki, Keisuke Kataoka, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Kentaro Ohki, Nobutaka Kiyokawa, Jiro Kagawa, Satoru Miyano, Akira Oka, Yasuhide Hayashi, Seishi Ogawa, Kiminori Terui, Atsushi Sato, Kenichiro Hata, Etsuro Ito, Junko Takita

Cancer science   110 ( 10 )   3358 - 3367   2019.9

Resistance of t(17;19)-acute lymphoblastic leukemia cell lines to multiagents in induction therapy.

Atsushi Watanabe, Takeshi Inukai, Keiko Kagami, Masako Abe, Masatoshi Takagi, Takashi Fukushima, Hiroko Fukushima, Toru Nanmoku, Kiminori Terui, Tatsuya Ito, Tsutomu Toki, Etsuro Ito, Junya Fujimura, Hiroaki Goto, Mikiya Endo, Thomas Look, Mark Kamps, Masayoshi Minegishi, Junko Takita, Toshiya Inaba, Hiroyuki Takahashi, Akira Ohara, Daisuke Harama, Tamao Shinohara, Shinpei Somazu, Hiroko Oshiro, Koshi Akahane, Kumiko Goi, Kanji Sugita

Cancer Med   8 ( 11 )   5274 - 5288   2019.7

MYH7 mutation identified by next-generation sequencing in three infant siblings with bi-ventricular noncompaction presenting with restrictive hemodynamics: A report of three siblings with a severe phenotype and poor prognosis.

Fumitake Miura, Jun Shimada, Yosuke Kitagawa, Katsuki Otani, Takumi Sato, Tsutomu Toki, Toru Takahashi, Susumu Yonesaka, Hiroki Mizukami, Etsuro Ito

Journal of cardiology cases   19 ( 4 )   140 - 143   2019.4

5歳で顕性化して遺伝子診断した橈尺骨癒合症を伴うDBA男児

松岡 正樹, 羽賀 洋一, 高橋 浩之, 村松 秀城, 土岐 力, 照井 君典, 伊藤 悦朗, 小原 明

日本小児科学会雑誌   123 ( 2 )   491 - 491   2019.2

Comprehensive genetic analyses of relapsed B-cell precursor acute lymphoblastic leukemia in children

Kubo Kaori, Kudo Ko, Toki Tsutomu, Ito Etsuro, Ikeda Fumika, Ito Tatsuya, Kobayashi Akie, Sato Tomohiko, Kamio Takuya, Sasaki Shinya

Hirosaki Medical Journal   70 ( 1 )   13 - 23   2019

Effective response to azacitidine in a child with a second relapse of myeloid leukemia associated with Down syndrome after bone marrow transplantation.

S. Uemura, T. Mori, C. Nagano, S. Takafuji, N. Nishimura, T. Toki, K. Terui, E. Ito, K. Iijima

Pediatric blood & cancer   65 ( 12 )   e27414 - e27414   2018.12

Two siblings with familial neuroblastoma with distinct clinical phenotypes harboring an ALK germline mutation.

Ko Kudo, Hiroo Ueno, Tomohiko Sato, Kaori Kubo, Rika Kanezaki, Akie Kobayashi, Takuya Kamio, Shinya Sasaki, Kiminori Terui, Akira Kurose, Kenichi Yoshida, Yusuke Shiozawa, Tsutomu Toki, Seishi Ogawa, Etsuro Ito

Genes, chromosomes & cancer   57 ( 12 )   665 - 669   2018.10

Effective response to azacitidine in a child with a second relapse of myeloid leukemia associated with Down syndrome after bone marrow transplantation.

Suguru Uemura, Takeshi Mori, China Nagano, Satoru Takafuji, Noriyuki Nishimura, Tsutomu Toki, Kiminori Terui, Etsuro Ito, Kazumoto Iijima

Pediatric blood & cancer   65 ( 12 )   e27414   2018.9

De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome.

Tsutomu Toki, Kenichi Yoshida, RuNan Wang, Sou Nakamura, Takanobu Maekawa, Kumiko Goi, Megumi C Katoh, Seiya Mizuno, Fumihiro Sugiyama, Rika Kanezaki, Tamayo Uechi, Yukari Nakajima, Yusuke Sato, Yusuke Okuno, Aiko Sato-Otsubo, Yusuke Shiozawa, Keisuke Kataoka, Yuichi Shiraishi, Masashi Sanada, Kenichi Chiba, Hiroko Tanaka, Kiminori Terui, Tomohiko Sato, Takuya Kamio, Hirotoshi Sakaguchi, Shouichi Ohga, Madoka Kuramitsu, Isao Hamaguchi, Akira Ohara, Hitoshi Kanno, Satoru Miyano, Seiji Kojima, Akira Ishiguro, Kanji Sugita, Naoya Kenmochi, Satoru Takahashi, Koji Eto, Seishi Ogawa, Etsuro Ito

American journal of human genetics   103 ( 3 )   440 - 447   2018.9

Atypical erythroblastosis in a patient with Diamond-Blackfan anemia who developed del(20q) myelodysplasia.

Sonoda M, Ishimura M, Ichimiya Y, Terashi E, Eguchi K, Sakai Y, Takada H, Hama A, Kanno H, Toki T, Ito E, Ohga S

International journal of hematology   108 ( 2 )   228 - 231   2018.8

Correction to: Atypical erythroblastosis in a patient with Diamond-Blackfan anemia who developed del(20q) myelodysplasia.

Motoshi Sonoda, Masataka Ishimura, Yuko Ichimiya, Eiko Terashi, Katsuhide Eguchi, Yasunari Sakai, Hidetoshi Takada, Asahito Hama, Hitoshi Kanno, Tsutomu Toki, Etsuro Ito, Shouichi Ohga

International journal of hematology   108 ( 2 )   236 - 236   2018.8

Diamond‐Blackfan貧血の診断的ターゲットおよびエクソームシーケンス解析

土岐力, 伊藤悦朗

小児科   59 ( 8 )   1203 - 1212   2018.7

Diagnostic targets and exosome sequence analysis of Diamond-Blackfan anemia in Japan

TOKI Tsutomu, ITO Etsuro

Rinsho Ketsueki   59 ( 7 )   945 - 952   2018

Purification of leukemic blast cells from blood smears using laser microdissection

Hidemasa Matsuo, Shuichi Shiga, Tsuyoshi Imai, Yasuhiko Kamikubo, Tsutomu Toki, Kiminori Terui, Etsuro Ito, Souichi Adachi

INTERNATIONAL JOURNAL OF HEMATOLOGY   106 ( 1 )   55 - 59   2017.7

Diagnostic challenge of Diamond-Blackfan anemia in mothers and children by whole-exome sequencing

Takuya Ichimura, Kenichi Yoshida, Yusuke Okuno, Toshiaki Yujiri, Kozo Nagai, Masanori Nishi, Yuichi Shiraishi, Hiroo Ueno, Tsutomu Toki, Kenichi Chiba, Hiroko Tanaka, Hideki Muramatsu, Toshiro Hara, Hitoshi Kanno, Seiji Kojima, Satoru Miyano, Etsuro Ito, Seishi Ogawa, Shouichi Ohga

INTERNATIONAL JOURNAL OF HEMATOLOGY   105 ( 4 )   515 - 520   2017.4

Exome sequencing identified RPS15A as a novel causative gene for Diamond-Blackfan anemia

Fumika Ikeda, Kenichi Yoshida, Tsutomu Toki, Tamayo Uechi, Shiori Ishida, Yukari Nakajima, Yoji Sasahara, Yusuke Okuno, Rika Kanezaki, Kiminori Terui, Takuya Kamio, Akie Kobayashi, Takashi Fujita, Aiko Sato-Otsubo, Yuichi Shiraishi, Hiroko Tanaka, Kenichi Chiba, Hideki Muramatsu, Hitoshi Kanno, Shouichi Ohga, Akira Ohara, Seiji Kojima, Naoya Kenmochi, Satoru Miyano, Seishi Ogawa, Etsuro Ito

HAEMATOLOGICA   102 ( 3 )   e93 - e96   2017.3

感染を契機に診断に至ったRPL11の遺伝子変異陽性Diamond-Blackfan anemiaの11歳男児例(原著論文/症例報告)

新居 敏, 藤野 寿典, 赤澤 嶺, 田尻 雄二朗, 高野 良彦, 土岐 力, 他

小児科臨床   69 ( 8 )   1416 - 1420   2016.8

Erythrocyte glutathione is a novel biomarker of Diamond-Blackfan anemia

Taiju Utsugisawa, Toshitaka Uchiyama, Tsutomu Toki, Hiromi Ogura, Takako Aoki, Isao Hamaguchi, Akira Ishiguro, Akira Ohara, Seiji Kojima, Shouichi Ohga, Etsuro Ito, Hitoshi Kanno

BLOOD CELLS MOLECULES AND DISEASES   59   31 - 36   2016.7

Systematic Cellular Disease Models Reveal Synergistic Interaction of Trisomy 21 and GATA1 Mutations in Hematopoietic Abnormalities

Kimihiko Banno, Sayaka Omori, Katsuya Hirata, Nobutoshi Nawa, Natsuki Nakagawa, Ken Nishimura, Manami Ohtaka, Mahito Nakanishi, Tetsushi Sakuma, Takashi Yamamoto, Tsutomu Toki, Etsuro Ito, Toshiyuki Yamamoto, Chikara Kokubu, Junji Takeda, Hidetoshi Taniguchi, Hitomi Arahori, Kazuko Wada, Yasuji Kitabatake, Keiichi Ozono

CELL REPORTS   15 ( 6 )   1228 - 1241   2016.5

ALDH2 polymorphism in patients with Diamond-Blackfan anemia in Japan

Fumika Ikeda, Tsutomu Toki, Rika Kanezaki, Kiminori Terui, Kenichi Yoshida, Hitoshi Kanno, Shouichi Ohga, Akira Ohara, Seiji Kojima, Seishi Ogawa, Etsuro Ito

INTERNATIONAL JOURNAL OF HEMATOLOGY   103 ( 1 )   112 - 114   2016.1

Recent advances in inherited bone marrow failure syndrome research

ITO Etsuro, TOKI Tsutomu, TERUI Kiminori

Rinsho Ketsueki   57 ( 7 )   882 - 890   2016

Transient myeloproliferative disorder with partial trisomy 21.

Takahide Takahashi, Akira Inoue, Junko Yoshimoto, Kiichiro Kanamitsu, Tomohiko Taki, Masahide Imada, Mutsuko Yamada, Shinsuke Ninomiya, Tsutomu Toki, Kiminori Terui, Etsuro Ito, Akira Shimada

Pediatric blood & cancer   62 ( 11 )   2021 - 2024   2015.11

Preserved High Probability of Overall Survival with Significant Reduction of Chemotherapy for Myeloid Leukemia in Down Syndrome: A Nationwide Prospective Study in Japan

Takashi Taga, Tomoyuki Watanabe, Daisuke Tomizawa, Kazuko Kudo, Kiminori Terui, Hiroshi Moritake, Akitoshi Kinoshita, Shotaro Iwamoto, Hideki Nakayama, Hiroyuki Takahashi, Akira Shimada, Tomohiko Taki, Tsutomu Toki, Etsuro Ito, Hiroaki Goto, Katsuyoshi Koh, Akiko M. Saito, Keizo Horibe, Tatsutoshi Nakahata, Akio Tawa, Souichi Adachi

PEDIATRIC BLOOD & CANCER   63 ( 2 )   248 - 254   2015.10

Transient Myeloproliferative Disorder With Partial Trisomy 21

Takahide Takahashi, Akira Inoue, Junko Yoshimoto, Kiichiro Kanamitsu, Tomohiko Taki, Masahide Imada, Mutsuko Yamada, Shinsuke Ninomiya, Tsutomu Toki, Kiminori Terui, Etsuro Ito, Akira Shimada

PEDIATRIC BLOOD & CANCER   62 ( 11 )   2021 - 2024   2015.7

Acute megakaryoblastic leukemia with acquired trisomy 21 and GATA1 mutations in phenotypically normal children

Rintaro Ono, Daisuke Hasegawa, Shinsuke Hirabayashi, Takahiro Kamiya, Kenichi Yoshida, Satoko Yonekawa, Chitose Ogawa, Ryota Hosoya, Tsutomu Toki, Kiminori Terui, Etsuro Ito, Atsushi Manabe

EUROPEAN JOURNAL OF PEDIATRICS   174 ( 4 )   525 - 531   2015.4

ダウン症候群に伴うTAM発症の分子機構

金崎 里香, 土岐 力, 伊藤 悦朗

日本産婦人科・新生児血液学会誌   25   49 - 54   2015

Molecular mechanisms underlying the pathology of Diamond-Blackfan anemia

TOKI Tsutomu, ITO Etsuro

Rinsho Ketsueki   56 ( 7 )   867 - 876   2015

Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia

RuNan Wang, Kenichi Yoshida, Tsutomu Toki, Takafumi Sawada, Tamayo Uechi, Yusuke Okuno, Aiko Sato-Otsubo, Kazuko Kudo, Isamu Kamimaki, Rika Kanezaki, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Kiminori Terui, Tomohiko Sato, Yuji Iribe, Shouichi Ohga, Madoka Kuramitsu, Isao Hamaguchi, Akira Ohara, Junichi Hara, Kumiko Goi, Kousaku Matsubara, Kenichi Koike, Akira Ishiguro, Yasuhiro Okamoto, Kenichiro Watanabe, Hitoshi Kanno, Seiji Kojima, Satoru Miyano, Naoya Kenmochi, Seishi Ogawa, Etsuro Ito

BRITISH JOURNAL OF HAEMATOLOGY   168 ( 6 )   854 - 864   2014.11

Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies

Yasuhiro Kazuki, Yuwna Yakura, Satoshi Abe, Mitsuhiko Osaki, Naoyo Kajitani, Kanako Kazuki, Shoko Takehara, Kazuhisa Honma, Hirofumi Suemori, Satoshi Yamazaki, Tetsushi Sakuma, Tsutomu Toki, Ritsuko Shimizu, Hiromitsu Nakauchi, Takashi Yamamoto, Mitsuo Oshimura

SCIENTIFIC REPORTS   4   6136   2014.8

Gene Alterations Involving the CRLF2-JAK Pathway and Recurrent Gene Deletions in Down Syndrome-Associated Acute Lymphoblastic Leukemia in Japan

Isamu Hanada, Kiminori Terui, Fumika Ikeda, Tsutomu Toki, Rika Kanezaki, Tomohiko Sato, Takuya Kamio, Ko Kudo, Shinya Sasaki, Yoshihiro Takahashi, Yasuhide Hayashi, Takeshi Inukai, Seiji Kojima, Kenichi Koike, Yoshiyuki Kosaka, Masao Kobayashi, Masue Imaizumi, Tetsuo Mitsui, Hiroki Hori, Junichi Hara, Keizo Horibe, Jun-ichi Nagai, Hiroaki Goto, Etsuro Ito

GENES CHROMOSOMES & CANCER   53 ( 11 )   902 - 910   2014.7

Novel in-frame deletion of <i>GATA1</i> observed in pediatric acute megakaryoblastic leukemia without down syndrome

Wang RuNan, Kanezaki Rika, Toki Tsutomu, Terui Kiminori, Sasaki Shinya, Kudo Ko, Kamio Takuya, Sato Tomohiko, Ikeda Fumika, Araki Ryo, Ochiai Hidetoshi, Ito Etsuro

Hirosaki Medical Journal   65 ( 2-4 )   227 - 237   2014

特集 造血器腫瘍のゲノム解析 ４.Down syndrome associated myeloid disorders

伊藤悦朗, 土岐力

血液フロンティア   24 ( 1 )   47 - 53   2013.12

The landscape of somatic mutations in Down syndrome-related myeloid disorders

Kenichi Yoshida, Tsutomu Toki, Yusuke Okuno, Rika Kanezaki, Yuichi Shiraishi, Aiko Sato-Otsubo, Masashi Sanada, Myoung-ja Park, Kiminori Terui, Hiromichi Suzuki, Ayana Kon, Yasunobu Nagata, Yusuke Sato, RuNan Wang, Norio Shiba, Kenichi Chiba, Hiroko Tanaka, Asahito Hama, Hideki Muramatsu, Daisuke Hasegawa, Kazuhiro Nakamura, Hirokazu Kanegane, Keiko Tsukamoto, Souichi Adachi, Kiyoshi Kawakami, Koji Kato, Ryosei Nishimura, Shai Izraeli, Yasuhide Hayashi, Satoru Miyano, Seiji Kojima, Etsuro Ito, Seishi Ogawa

NATURE GENETICS   45 ( 11 )   1293 - +   2013.11

Clonal selection in xenografted TAM recapitulates the evolutionary process of myeloid leukemia in Down syndrome

Satoshi Saida, Ken-ichiro Watanabe, Aiko Sato-Otsubo, Kiminori Terui, Kenichi Yoshida, Yusuke Okuno, Tsutomu Toki, RuNan Wang, Yuichi Shiraishi, Satoru Miyano, Itaru Kato, Tatsuya Morishima, Hisanori Fujino, Katsutsugu Umeda, Hidefumi Hiramatsu, Souichi Adachi, Etsuro Ito, Seishi Ogawa, Mamoru Ito, Tatsutoshi Nakahata, Toshio Heike

BLOOD   121 ( 21 )   4377 - 4387   2013.5

Naturally occurring oncogenic GATA1 mutants with internal deletions in transient abnormal myelopoiesis in Down syndrome

Tsutomu Toki, Rika Kanezaki, Eri Kobayashi, Hiroshi Kaneko, Mikiko Suzuki, RuNan Wang, Kiminori Terui, Hirokazu Kanegane, Miho Maeda, Mikiya Endo, Tatsuki Mizuochi, Souichi Adachi, Yasuhide Hayashi, Masayuki Yamamoto, Ritsuko Shimizu, Etsuro Ito

Blood   121 ( 16 )   3181 - 3184   2013.4

Down syndrome associated myeloid disorders

土岐 力

血液フロンティア   24   47 - 53   2013

新生児科医のためのTAM診療ガイドラインTAM発症の分子機構

照井 君典, 土岐 力

日本周産期・新生児医学会雑誌   49   20 - 22   2013

ダウン症候群関連急性リンパ性白血病におけるJAK2およびCRLF2遺伝子異常

照井 君典, 土岐 力

日本小児血液・がん学会雑誌   50   11 - 14   2013

A Novel Mutation of Ribosomal Protein S10 Gene in a Japanese Patient With Diamond-Blackfan Anemia

Makoto Yazaki, Michi Kamei, Yasuhiko Ito, Yuki Konno, RuNan Wang, Tsutomu Toki, Etsuro Ito

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY   34 ( 4 )   293 - 295   2012.5

[Transient myeloproliferative disorder in Down syndrome].

Ito E, Toki T

Nihon rinsho. Japanese journal of clinical medicine   70 Suppl 2   687 - 91   2012.4

Identification of TRIB1 R107L gain-of-function mutation in human acute megakaryocytic leukemia

Takashi Yokoyama, Tsutomu Toki, Yoshihiro Aoki, Rika Kanezaki, Myoung-ja Park, Yohei Kanno, Tomoko Takahara, Yukari Yamazaki, Etsuro Ito, Yasuhide Hayashi, Takuro Nakamura

BLOOD   119 ( 11 )   2608 - 2611   2012.3

Extensive gene deletions in Japanese patients with Diamond-Blackfan anemia

Madoka Kuramitsu, Aiko Sato-Otsubo, Tomohiro Morio, Masatoshi Takagi, Tsutomu Toki, Kiminori Terui, RuNan Wang, Hitoshi Kanno, Shouichi Ohga, Akira Ohara, Seiji Kojima, Toshiyuki Kitoh, Kumiko Goi, Kazuko Kudo, Tadashi Matsubayashi, Nobuo Mizue, Michio Ozeki, Atsuko Masumi, Haruka Momose, Kazuya Takizawa, Takuo Mizukami, Kazunari Yamaguchi, Seishi Ogawa, Etsuro Ito, Isao Hamaguchi

BLOOD   119 ( 10 )   2376 - 2384   2012.3

Down症に伴う骨髄増殖症

土岐 力

日本臨床   70   687 - 91   2012

Nrf2 regulates ferroportin 1-mediated iron efflux and counteracts lipopolysaccharide-induced ferroportin 1 mRNA suppression in macrophages

Nobuhiko Harada, Masaya Kanayama, Atsushi Maruyama, Aruto Yoshida, Kyoko Tazumi, Tomonori Hosoya, Junsei Mimura, Tsutomu Toki, Jonathan M. Maher, Masayuki Yamamoto, Ken Itoh

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS   508 ( 1 )   101 - 109   2011.4

一過性骨髄異常増殖症(TAM)発症の分子機構

土岐 力

日本小児血液学会雑誌   25   171 - 8   2011

Down syndrome and GATA1 mutations in transient abnormal myeloproliferative disorder: mutation classes correlate with progression to myeloid leukemia

Rika Kanezaki, Tsutomu Toki, Kiminori Terui, Gang Xu, RuNan Wang, Akira Shimada, Asahito Hama, Hirokazu Kanegane, Kiyoshi Kawakami, Mikiya Endo, Daisuke Hasegawa, Kazuhiro Kogawa, Souichi Adachi, Yasuhiko Ikeda, Shotaro Iwamoto, Takashi Taga, Yoshiyuki Kosaka, Seiji Kojima, Yasuhide Hayashi, Etsuro Ito

BLOOD   116 ( 22 )   4631 - 4638   2010.11

Selective KIT inhibitor KI-328 and HSP90 inhibitor show different potency against the type of KIT mutations recurrently identified in acute myeloid leukemia

Akane Tsujimura, Hitoshi Kiyoi, Yukimasa Shiotsu, Yuichi Ishikawa, Yumiko Mori, Hiroshi Ishida, Tsutomu Toki, Etsuro Ito, Tomoki Naoe

INTERNATIONAL JOURNAL OF HEMATOLOGY   92 ( 4 )   624 - 633   2010.11

Molecular pathogenesis in Diamond-Blackfan anemia

Etsuro Ito, Yuki Konno, Tsutomu Toki, Kiminori Terui

INTERNATIONAL JOURNAL OF HEMATOLOGY   92 ( 3 )   413 - 418   2010.10

典型例とは異なる緩徐な臨床経過を示し、リボソームタンパク遺伝子RPL11の変異の検出により診断したDiamond-Blackfan貧血の1例

佐野 弘純, 朴 明子, 外松 学, 今野 友貴, 土岐 力, 伊藤 悦朗, 林 泰秀

日本小児血液学会雑誌   24 ( 4 )   225 - 228   2010.8

Mutations in the ribosomal protein genes in Japanese patients with Diamond-Blackfan anemia

Yuki Konno, Tsutomu Toki, Satoru Tandai, Gang Xu, RuNan Wang, Kiminori Terui, Shouichi Ohga, Toshiro Hara, Asahito Hama, Seiji Kojima, Daiichiro Hasegawa, Yoshiyuki Kosaka, Ryu Yanagisawa, Kenichi Koike, Rie Kanai, Tsuyoshi Imai, Teruaki Hongo, Myoung-Ja Park, Kanji Sugita, Etsuro Ito

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL   95 ( 8 )   1293 - 1299   2010.8

Exposure to a MRI-Type High-Strength Static Magnetic Field Stimulates Megakaryocytic/Erythroid Hematopoiesis in CD34(+) Cells From Human Placental and Umbilical Cord Blood

Satoru Monzen, Kenji Takahashi, Tsutomu Toki, Etsuro Ito, Tomonori Sakurai, Junji Miyakoshi, Ikuo Kashiwakura

BIOELECTROMAGNETICS   30 ( 4 )   280 - 285   2009.5

小児科領域の血液疾患 一過性骨髄増殖性疾患

土岐 力, 照井 君典

日本検査血液学会雑誌 10   457 - 464   2009

一過性骨髄増殖症.小児疾患診療のための病態生理

土岐 力, 照井 君典

小児内科増刊号 41   1183 - 1186   2009

一過性骨髄増殖症

土岐 力

小児疾患診療のための病態生理小児内科増刊号 41   1183 - 1186   2009

The key role of stem cell factor/KIT signaling in the proliferation of blast cells from Down syndrome-related leukemia

土岐 力

Leukemia   23 ( 1 )   95 - 103   2009

Construction of an expression system for aqualysin I in Escherichia coli that gives a markedly improved yield of the enzyme protein

Masayoshi Sakaguchi, Keisuke Niimiya, Makoto Takezawa, Tsutomu Toki, Yasusato Sugahara, Masao Kawakita

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   72 ( 8 )   2012 - 2018   2008.8

Functional analysis of JAK3 mutations in transient myeloproliferative disorder and acute megakaryoblastic leukaemia accompanying Down syndrome

Tomohiko Sato, Tsutomu Toki, Rika Kanezaki, Gang Xu, Kiminori Terui, Hirokazu Kanegane, Masayoshi Miura, Souichi Adachi, Masahiro Migita, Shingo Morinaga, Takahide Nakano, Mikiya Endo, Seiji Kojima, Hitoshi Kiyoi, Hiroyuki Mano, Etsuro Ito

BRITISH JOURNAL OF HAEMATOLOGY   141 ( 5 )   681 - 688   2008.6

Edaravone inhibits the expression of vascular endothelial growth factor in human astrocytes exposed to hypoxia

Akira Ishikawa, Hidemi Yoshida, Norifumi Metoki, Tsutomu Toki, Tadaatsu Imaizumi, Tomoh Matsumiya, Koji Yamashita, Kageaki Taima, Kei Satoh

NEUROSCIENCE RESEARCH   59 ( 4 )   406 - 412   2007.12

Correction of immunodeficiency associated with NEMO mutation by umbilical cord blood transplantation using a reduced-intensity conditioning regimen.

Tono C, Takahashi Y, Terui K, Sasaki S, Kamio T, Tandai S, Sato T, Kudo K, Toki T, Tachibana N, Yoshioka T, Nakahata T, Morio T, Nishikomori R, Ito E.

Bone Marrow Transplantation   39 ( 12 )   801 - 804   2007.4

[The molecular mechanism of leukemogenesis in Down syndrome-related acute megakaryocytic leukemia].

Ito E, Toki T

Nihon rinsho. Japanese journal of clinical medicine   65 Suppl 1   136 - 140   2007.1

Development of acute megakaryoblastic leukemia from a minor clone in a Down syndrome patient with clinically overt transient myeloproliferative disorder

Gang Xu, Koji Kato, Tsutomu Toki, Yoshihiro Takahashi, Kiminori Terui, Etsuro Ito

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY   28 ( 10 )   696 - 698   2006.10

Physical association of the patient-specific GATA1 mutants with RUNX1 in acute megakaryoblastic leukemia accompanying Down syndrome.

Xu G, Kanezaki R, Toki T, Watanabe S, Takahashi Y, Terui K, Kitabayashi I, Ito E.

Leukemia   20 ( 6 )   1002 - 1008   2006.6

Cloning and Characterization of the Novel Chimeric Gene p53/FXR2 in the Acute Megakaryoblastic Leukemia Cell Line CMK11-5

Kanezaki Rika, Toki Tsutomu, Xu Gang, Narayanan Ramswamy, Ito Etsuro

The Tohoku Journal of Experimental Medicine   209 ( 3 )   169 - 180   2006

JAK2 Val617Phe activating tyrosine kinase mutation in juvenile myelomonocytic leukemia.

Tono C, Xu G, Toki T, Takahashi Y, Sasaki S, Terui K, Ito E.

Leukemia   19 ( 10 )   1843 - 1844   2005.10

The proto-oncogene ERG in megakaryoblastic leukemias

L Rainis, T Toki, JE Pimanda, E Rosenthal, K Machol, S Strehl, B Gottgens, E Ito, S Izraeli

CANCER RESEARCH   65 ( 17 )   7596 - 7602   2005.9

Roxithromycin is an inhibitor of human coronary artery smooth muscle cells proliferation: a potential ability to prevent coronary heart disease

H Tomita, T Osanai, T Toki, N Maeda, R Murakami, ZN Chen, H Yamabe, H Osawa, M Yasujima, K Okumura

ATHEROSCLEROSIS   182 ( 1 )   87 - 95   2005.9

Troglitazone and 15-deoxy-Delta(12,14)-prostaglandin J(2) inhibit shear-induced coupling factor 6 release in endothelial cells

H Tomita, T Osanai, T Toki, S Sasaki, N Maeda, R Murakami, K Magota, M Yasujima, K Okumura

CARDIOVASCULAR RESEARCH   67 ( 1 )   134 - 141   2005.7

KCNJ2 mutation in intractable ventricular arrhythmia with Andersen's syndrome.

Takahashi T, Tandai S, Toki T, Sato T, Eto S, Sato A, Ueda T, Sato S, Ichinose K, Ito E, Yonesaka S

Pediatrics international : official journal of the Japan Pediatric Society   47 ( 2 )   220 - 223   2005.4

Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment

T Toki, F Katsuoka, F Kanezaki, G Xu, H Kurotaki, JY Sun, T Kamio, S Watanabe, S Tandai, K Terui, S Yagihashi, N Komatsu, K Igarashi, M Yamamoto, E Ito

BLOOD   105 ( 8 )   3100 - 3108   2005.4

The GATA1 mutation in an adult patient with acute megakaryoblastic leukemia not accompanying Down syndrome.

Harigae H, Xu G, Sugawara T, Ishikawa I, Toki T, Ito E

Blood   103 ( 8 )   3242 - 3243   2004.4

21q11-21領域からの一過性骨髄異常増殖症の原因遺伝子単離の試み

石崎典子, 金崎里香, 土岐力, 伊藤悦朗

弘前医学   55 ( 3-4 )   83 - 94   2004.3

Fetal origin of the GATA1 mutation in identical twins with transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down syndrome.

Shimada A, Xu G, Toki T, Kimura H, Hayashi Y, Ito E

Blood   103 ( 1 )   366   2004.1

Three novel mutations of the fibrillin-1 gene and ten single nucleotide polymorphisms of the fibrillin-3 gene in Marfan syndrome patients

Tomomi Uyeda, Toru Takahashi, Shuji Eto, Takumi Sato, Gang Xu, Rika Kanezaki, Tsutomu Toki, Susumu Yonesaka, Etsuro Ito

Journal of Human Genetics   49 ( 8 )   404 - 407   2004

A trial of isolating the novel genes on 21q11-21 to elucidate the gene responsible for transient abnormal myelopoiesis

Ishizaki Noriko, Kanezaki Rika, Toki Tsutomu, Ito Etsuro

Hirosaki Medical Journal   55 ( 3-4 )   83 - 94   2004

B-cell-specific transcription factor BACH2 modifies the cytotoxic effects of anticancer drugs.

Kamio T, Toki T, Kanezaki R, Sasaki S, Tandai S, Terui K, Ikebe D, Igarashi K, Ito E

Blood   102 ( 9 )   3317 - 3322   2003.11

Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome

G Xu, M Nagano, R Kanezaki, T Toki, Y Hayashi, T Taketani, T Taki, T Mitui, K Koike, K Kato, M Imaizumi, Sekine, I, Y Ikeda, R Hanada, M Sako, K Kudo, S Kojima, O Ohneda, M Yamamoto, E Ito

BLOOD   102 ( 8 )   2960 - 2968   2003.10

Glycogen synthase kinase-3 beta phosphorylates synphilin-1 in vitro

K Tanji, T Toki, W Tamo, T Imaizumi, T Matsumiya, F Mori, H Takahashi, K Satoh, K Wakabayashi

NEUROPATHOLOGY   23 ( 3 )   199 - 202   2003.9

B Cell Specific Transcription Factor BACH2 Negatively Regulates Expression of BCL-2 Related A1 Gene

TANDAI Satoru, SATO Hideko, KANEZAKI Rika, TOKI Tsutomu, IGARASHI Kazuhiko, ITO Etsuro

The Hirosaki medical journal   54 ( 1 )   8 - 20   2002

Transcription factor BACH1 is recruited to the nucleus by its novel alternative spliced isoform.

R Kanezaki, T Toki, M Yokoyama, K Yomogida, K Sugiyama, M Yamamoto, K Igarashi, E Ito

The Journal of biological chemistry   276 ( 10 )   7278 - 7284   2001.3

Desferrioxamine, an iron chelator, upregulates cyclooxygenase-2 expression and prostaglandin production in a human macrophage cell line.

K Tanji, T Imaizumi, T Matsumiya, H Itaya, K Fujimoto, X Cui, T Toki, E Ito, H Yoshida, K Wakabayashi, K Satoh

Biochimica et biophysica acta   1530 ( 2-3 )   227 - 235   2001.2

Identification of the Target Genes for B Cell Specific Transcription Factor BACH2

SATO Hideko, SASAKI Shinya, KANEZAKI Rika, TOKI Tsutomu, ITO Etsuro

The Hirosaki medical journal   53 ( 2 )   73 - 81   2001

Expression of transcription factors during megakaryocytic differentiation of CD34+ cells from human cord blood induced by thrombopoietin.

K Terui, Y Takahashi, J Kitazawa, T Toki, M Yokoyama, E Ito

The Tohoku journal of experimental medicine   192 ( 4 )   259 - 273   2000.12

Functional characterization of the two alternative promoters of human p45 NF-E2 gene.

T Toki, K Arai, K Terui, N Komatsu, M Yokoyama, F Katsuoka, M Yamamoto, E Ito

Experimental hematology   28 ( 10 )   1113 - 1119   2000.10

Cloning and expression of human B cell-specific transcription factor BACH2 mapped to chromosome 6q15.

S Sasaki, E Ito, T Toki, T Maekawa, R Kanezaki, T Umenai, A Muto, H Nagai, T Kinoshita, M Yamamoto, J Inazawa, M M Taketo, T Nakahata, K Igarashi, M Yokoyama

Oncogene   19 ( 33 )   3739 - 3749   2000.8

Expression of Transcription Factors during Megakaryocytic Differentiation of CD34+ Cells from Human Cord Blood Induced by Thrombopoietin

Terui Kiminori, Takahashi Yoshihiro, Kitazawa Junichi, Toki Tsutomu, Yokoyama Masaru, Ito Etsuro

The Tohoku Journal of Experimental Medicine   192 ( 4 )   259 - 273   2000

Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3.

A Kobayashi, E Ito, T Toki, K Kogame, S Takahashi, K Igarashi, N Hayashi, M Yamamoto

The Journal of biological chemistry   274 ( 10 )   6443 - 6452   1999.3

Erythroid accelerating factor detected in serum from rats with drug induced hemolysis.

M Kasai, M Yokoyama, T Toki, H Maruyama, K Satoh, E Itoh

The Tohoku journal of experimental medicine   186 ( 4 )   279 - 289   1998.12

Progression from myelodysplastic syndrome with monosomy 7 to acute monoblastic leukemia with MLL gene rearrangement.

J Kitazawa, T Umenai, E Ito, K Arai, H Otomo, T Toki, M Seto, R Ueda, M Yokoyama

International journal of hematology   67 ( 1 )   23 - 26   1998.1

Structure and chromosome mapping of the human small maf-genes MAFG and MAFK.

T Iwata, K Kogame, T Toki, M Yokoyama, M Yamamoto, E Ito

Cytogenetics and cell genetics   82 ( 1-2 )   88 - 90   1998

Erythroid Accelerating Factor Detected in Serum from Rats with Drug Induced Hemolysis.

Kasai Mikio, Yokoyama Masaru, Toki Tsutomu, Maruyama Hidekazu, Satoh Kei, Itoh Etsuro

The Tohoku Journal of Experimental Medicine   186 ( 4 )   279 - 289   1998

Study on Prognostic Factor in the Children with Aplastic Anemia

KAIZUKA Michiko, INOUE Sinjo R., TOKI Tsutomu, et al.

11 ( 2 )   84 - 87   1997.4

Study on Prognosis and Prognostic Factor in Children with Aplastic Anemia, Experienced for Past 3 Decades

KAIZUKA Michiko, INOUE Sinjo R., TOKI Tsutomu, ITO Etsuro, YOKOYAMA Masaru

11 ( 2 )   79 - 83   1997.4

Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif.

T Toki, J Itoh, J Kitazawa, K Arai, K Hatakeyama, J Akasaka, K Igarashi, N Nomura, M Yokoyama, M Yamamoto, E Ito

Oncogene   14 ( 16 )   1901 - 1910   1997.4

Study on Prognostic Factor in the Children with Aplastic Anemia.

KAIZUKA Michiko, INOUE Sinjo R., TOKI Tsutomu, ITO Etsuro, YOKOYAMA Masaru

The Japanese Journal of Pediatric Hematology   11 ( 2 )   84 - 87   1997

Study on Prognosis and Prognostic Factor in Children with Aplastic Anemia, Experienced for Past 3 Decades.

KAIZUKA Michiko, INOUE Sinjo R., TOKI Tsutomu, ITO Etsuro, YOKOYAMA Masaru

The Japanese Journal of Pediatric Hematology   11 ( 2 )   79 - 83   1997

Expression of erythroid-specific genes in megakaryoblastic disorders.

E Ito, M Kasai, T Toki, K Arai, M Yokoyama

Leukemia & lymphoma   23 ( 5-6 )   545 - 550   1996.11

Analysis of Clinical Characteristics on Infantile Leukemia

ARAI Koji, ITO Etsuro, TOKI Tsutomu, et al.

The Japanese Journal of Pediatric Hematology   10 ( 5 )   344 - 350   1996.10

Abundant expression of erythroid transcription factor P45 NF-E2 mRNA in human peripheral granurocytes.

T Toki, J Itoh, K Arai, J Kitazawa, M Yokoyama, K Igarashi, M Yamamoto, E Ito

Biochemical and biophysical research communications   219 ( 3 )   760 - 765   1996.2

Analysis of Clinical Characteristics on Infantile Leukemia.

ARAI Koji, ITO Etsuro, TOKI Tsutomu, TERUI Kiminori, ANZAI Yukiko, OKA Toshiaki, ISHIKAWA Yorikazu, KUDO Toru, TAKEDA Takeo, TACHIBANA Naoki, TAKANO Nagakuni, WATANABE Arata, YOKOYAMA Shinkichi, IMAIZUMI Masue, KIKUTA Atsushi, TANAKA Atsushi, YOKOYAMA Masaru

The Japanese Journal of Pediatric Hematology   10 ( 5 )   344 - 350   1996

Erythroid Transcription Factors in Hematopoietic Cells.

ITO Etsuro, TOKI Tsutomu

The Japanese Journal of Pediatric Hematology   10 ( 1 )   8 - 17   1996

Anemia in Children with Neurological Diseases - Influence of Antiepileptic Drugs -

Mutsuko Shiotani, Norio Onodera, Tsutomu Toki, et al.

Hirosaki Medical Journal   46   254 - 259   1995.12

Expression of erythroid-specific genes in acute megakaryoblastic leukaemia and transient myeloproliferative disorder in Down's syndrome.

E Ito, M Kasai, Y Hayashi, T Toki, et al

British journal of haematology   90 ( 3 )   607 - 614   1995.7

Erythroid transcription factor GATA-1 is abundantly transcribed in mouse testis.

E Ito, T Toki, H Ishihara, et al.

Nature   362 ( 6419 )   466 - 468   1993.4

Expression of a lineage specific transcriptional factor GATA-1 in leukaemic blasts from patients with infantile leukaemia.

E Ito, T Toki, K Arai, K Kawauchi, H Tsuda, M Yokoyama

British journal of haematology   80 ( 4 )   561 - 563   1992.4

The Alteration of Intracellular Enzyme Activities during Stimulation on Erythropoiesis. In vivo and in vitro Studies

Tsutomu Toki, Masaru Yokoyama

The Japanese Journal of Pediatric Hematology   5 ( 2 )   145 - 150   1991.5

The Alteration of Intracellular Enzyme Activities during Stimulation on Erythropoiesis. In vivo and in vitro Studies.

TOKI Tsutomu, YOKOYAMA Masaru

The Japanese Journal of Pediatric Hematology   5 ( 2 )   145 - 150   1991

The frequency of platelet count abnormality among junior high school students and quantitative, qualiative changes of platelets during treatment for adolescent iron deficiency anemia.

Yoshimasa Suto, Taketora Echizenya, Hiroyuki Kasetani, et al.

The Japanese Journal of Pediatric Hematology   4 ( 4 )   342 - 347   1990.4

The frequency of platelet count abnormality among junior high school students and quantitative, qualiative changes of platelets during treatment for adolescent iron deficiency anemia.

SUTO Yoshimasa, ECHIZENYA Taketora, KASETANI Hiroyuki, ARAI Kouji, TOKI Tsutomu, KAWAUCHI Kyouichi, SATO Yuichi, YOKOYAMA Masaru

The Japanese Journal of Pediatric Hematology   4 ( 4 )   342 - 347   1990

Severe Aplastic Anemia Successfully Treated with Cyclosporin A and Prednisolone

Ryousuke Ito, Kyoichi Kawauchi, Tsutomu Toki, et al.

The Japanese Journal of Clinical Hematology   30 ( 12 )   2157 - 2162   1989.12

The Effect of Hormones on Erythropoiesis

Hiroyuki Kasetani, Tsutomu Toki, Masaru Yokoyama

The Japanese Journal of Pediatric Hematology   3 ( 4 )   325 - 332   1989.4

The Alteration of Erythrocyte-GOT Activity and Erythropoietic Status in Various Blood Diseases

Tsutomu Toki, Ryosuke Ito, Hiroyuki Kasetani, et al.

The Japanese Journal of Pediatric Hematology   2   325 - 330   1989.1

Severe Aplastic Anemia Successfully Treated with Cyclosporin A and Prednisolone

ITO Ryosuke, KAWAUCHI Kyoichi, TOKI Tsutomu, KASAI Mikio, ARAI Koji, SAITO Tosimitu, MIYANO Takakazu, SATO Yuichi, YOKOYAMA Masaru

Rinsho Ketsueki   30 ( 12 )   2157 - 2162   1989

The Alteration of Intracellular Cyclic Nucleotides Levels during Stimulation on Erythropoiesis

TOKI Tsutomu, KASETANI Hiroyuki, ARAI Kouji, YOKOYAMA Masaru

The Japanese Journal of Pediatric Hematology   3 ( 4 )   345 - 350   1989

The Effect of Hormones on Erythropoiesis

KASETANI Hiroyuki, TOKI Tsutomu, YOKOYAMA Masaru

The Japanese Journal of Pediatric Hematology   3 ( 4 )   325 - 332   1989

一過性骨髄異常増殖症の寛解を経ずにDown症候群関連骨髄性白血病を発症した1例

小林明恵, 梅津英典, 遅野井香純, 佐藤知彦, 神尾卓哉, 工藤耕, 佐々木伸也, 土岐力, 照井君典, 伊藤悦朗

日本小児科学会雑誌   124 ( 7 )   2020

一過性骨髄異常増殖症の寛解を経ずにDown症候群関連骨髄性白血病を発症した1例

小林明恵, 佐藤知彦, 神尾卓哉, 工藤耕, 佐々木伸也, 土岐力, 照井君典, 伊藤悦朗

日本小児科学会雑誌   124 ( 2 )   2020

Predictive Factors of the Development of Leukemia in Patients with Transient Abnormal Myelopoiesis and Down Syndrome: The Jccg Study JPLSG TAM-10

Genki Yamato, Hideki Muramatsu, Tomoyuki Watanabe, Takao Deguchi, Shotaro Iwamoto, Daisuke Hasegawa, Kiminori Terui, Takahiro Ueda, Tomoko Yokosuka, Tsutomu Toki, Shiro Tanaka, Ryu Yanagisawa, Katsuyoshi Koh, Akiko M. Saito, Keizo Horibe, Yasuhide Hayashi, Souichi Adachi, Shuki Mizutani, Takashi Taga, Etsuro Ito, Kenichiro Watanabe

BLOOD   134   2019.11

先天性骨髄不全症の診断基準・重症度分類・診療ガイドラインの確立に関する研究 DBAの遺伝子診断・診療ガイドラインの作成

伊藤悦朗, 土岐力, 神尾卓哉, 佐藤知彦

先天性骨髄不全症の診断基準・重症度分類・診療ガイドラインの確立に関する研究 平成30年度 総括・分担研究報告書(Web)   2019

Diamond-Blackfan貧血の診断的ターゲットおよびエクソームシーケンス解析

土岐力, 伊藤悦朗

小児科   59 ( 8 )   1203 - 1212   2018.12

【小児疾患診療のための病態生理　3　改訂第5版】 血液・腫瘍性疾患　一過性異常骨髄増殖症

照井 君典, 土岐 力, 伊藤 悦朗

小児内科   48   953 - 956   2018.7

Diagnostic target and exosome sequence analysis of Diamond-Blackfan anemia in Japan

Tsutomu Toki, Etsuro Ito

The Japanese Journal of Clinical Hematology   59 ( 7 )   945 - 952   2018.7

Down syndrome

Esturo Ito, Tsutomu Toki, Kiminori Teruii

74 ( 8 )   97 - 102   2016.10

白血病の疫学と危険因子　白血病発症の危険因子　先天性染色体異常症と家族性腫瘍症候群　Down症候群

伊藤悦朗, 土岐力, 照井君典

[白血病学(上)-最新の基礎、臨床研究-]   74 ( 8 )   97 - 102   2016.10

【小児血液疾患における遺伝子変異の探索】 遺伝性骨髄不全症研究の最近の進歩(解説/特集)

伊藤 悦朗, 土岐 力, 照井 君典

臨床血液   57 ( 7 )   882 - 890   2016.7

Recent advances in inherited bone marrow failure syndrome research

Ito E, Toki T, Terui K.

Rinsho Ketueki   57 ( 7 )   882 - 890   2016.7

Molecular mechanisms underlying the pathology of Diamond-Blackfan anemia

Tsutomu Toki, Etsurou Ito

The Japanese Journal of Clinical Hematology   56 ( 7 )   867 - 876   2015.7

ダウン症候群に伴うTAM発症の分子機構

照井君典, 金崎里香, 土岐　力, 伊藤悦朗

日本産婦人科・新生児血液学会誌   25 ( 1 )   49 - 54   2015.5

Molecular pathogenesis of myeloid proliferations related to Down syndrome

Hematology   69 ( 2 )   200 - 206   2014.8

【造血器腫瘍のゲノム解析】 Down syndrome associated myeloid disorders

伊藤悦朗, 土岐　力

血液フロンティア   24 ( 1 )   47 - 53   2013.12

TAM発症の分子機構

伊藤 悦朗, 金崎 理香, 王 汝南, 照井 君典, 土岐 力

日本周産期・新生児医学会雑誌 = Journal of Japan Society of Perinatal and Neonatal Medicine   49 ( 1 )   20 - 22   2013.5

新生児科医のためのTAM診療ガイドライン TAM発症の分子機構

伊藤悦朗, 金崎里香, 王　汝南, 照井君典, 土岐　力

日本周産期・新生児医学会雑誌   49 ( 1 )   20 - 22   2013.5

小児ALLにおけるCRLF2、IKZF1、JAK2遺伝子の臨床的意義 ダウン症候群関連急性リンパ性白血病におけるJAK2およびCRLF2遺伝子異常

照井君典, 花田　勇, 土岐　力, 他

日本小児血液・がん学会雑誌   50 ( 1 )   11 - 14   2013.4

本邦における骨髄不全症候群の現況 先天性赤芽球癆(Diamond-Blackfan貧血)の効果的診断法の確立に関する研究

伊藤悦朗, 照井君典, 土岐　力, 他

日本小児血液・がん学会雑誌   49 ( 3 )   256 - 263   2012.10

Transient myeloproliferative disorder in Down syndrome

Nihon Rinsho   70 ( S2 )   687 - 691   2012.4

一過性骨髄異常増殖症（TAM）発症の分子機構(総論).

土岐力、伊藤悦朗

日本小児血液学会雑誌   25   171 - 178   2011.9

Molecular pathogenesis in Diamond-Blackfan anemia

Ito E, Konno Y, Toki T, Terui K.

Int J Hematol.   92 ( 3 )   413 - 418   2010.8

小児科領域の血液疾患 一過性骨髄増殖性疾患(解説)

伊藤悦朗, 土岐力, 金崎理香, 佐藤知彦, 照井君典, 足立壮一

日本検査血液学会雑誌   10 ( 3 )   457 - 464   2009.11

【小児疾患診療のための病態生理】 血液・腫瘍性疾患　一過性異常骨髄増殖症(解説/特集)

土岐力, 照井君典, 伊藤悦朗

小児内科   41 ( 増刊 )   1183 - 1186   2009.8

The molecular mechanism of leukemogenesis in Down syndrome-related acute megakaryocytic leukemia

65 ( 増刊1 )   136 - 140   2007.1

【そこが知りたい小児臨床検査のポイント】　血液一般検査　赤血球検査　赤血球浸透圧抵抗試験,自己溶血試験(解説/特集)

土岐　力, 伊藤悦朗

小児内科   37 ( 増刊 )   72 - 74   2005.11

赤血球造血と疾患

伊藤 悦朗, 土岐 力

日本小児科学会雑誌   109 ( 5 )   605 - 613   2005.5

赤血球造血と疾患(総説)

伊藤悦朗, 土岐　力

日本小児科学会雑誌   109 ( 5 )   605 - 613   2005.5

C1-1 TAMの病態(委員会セッション 骨髄異形成症候群,第21回日本小児がん学会 第47回日本小児血液学会 同時期開催)

伊藤 悦朗, 土岐 力

小児がん : 小児悪性腫瘍研究会記録   42 ( 3 )   2005

【造血器腫瘍における転写因子研究の進歩】　GATA転写因子と白血病(解説/特集)

伊藤悦朗, 土岐　力

血液・腫瘍科   49 ( 1 )   42 - 49   2004.7

A TRIAL OF ISOLATING THE NOVEL GENES ON 21q11-21 TO ELUCIDATE THE GENE RESPONSIBLE FOR TRANSIENT ABNORMAL MYELOPOIESIS

Ishizaki Noriko, Kanezaki Rika, Toki Tsutomu, Ito Etsuro

The Hirosaki medical journal   55 ( 3 )   83 - 94   2004

B Cell Specific Transcription Factor BACH2 Negatively Regulates Expression of BCL-2 Related A1 Gene

TANDAI Satoru, SATO Hideko, KANEZAKI Rika, TOKI Tsutomu, IGARASHI Kazuhiko, ITO Etsuro

The Hirosaki medical journal   54 ( 1 )   8 - 20   2002

Function of Tissue Specific Transcription Factors in Proliferation and Differentiation of Hematopoietic Cells (Scientific Achievement Award, Hirosaki University School of Medicine, 2001. For Distinguished Scholars.)

TOKI Tsutomu

The Hirosaki medical journal   53 ( 3 )   126 - 128   2002

BACH転写因子群と小児白血病

伊藤 悦朗, 土岐 力

日本小児科学会雑誌   105 ( 10 )   1037 - 1042   2001.10

Identification of the Target Genes for B Cell Specific Transcription Factor BACH2

SATO Hideko, SASAKI Shinya, KANEZAKI Rika, TOKI Tsutomu, ITO Etsuro

The Hirosaki medical journal   53 ( 2 )   73 - 81   2001

Roles of NF-E2 related transcription factors in hematopoietic cell differentiation

Etsuro Ito, Tsutomu Toki

Hematology & Oncology   40 ( 6 )   535 - 540   2000.6

Study on Prognosis and Prognostic Factor in Children with Aplastic Anemia, Experienced for Past 3 Decades.

KAIZUKA Michiko, INOUE Sinjo R, TOKI Tsutomu, ITO Etsuro, YOKOYAMA Masaru

The Japanese Journal of Pediatric Hematology   11 ( 2 )   79 - 83   1997

Study on Prognostic Factor in the Children with Aplastic Anemia.

KAIZUKA Michiko, INOUE Sinjo R, TOKI Tsutomu, ITO Etsuro, YOKOYAMA Masaru

The Japanese Journal of Pediatric Hematology   11 ( 2 )   84 - 87   1997

Erythroid Transcription Factors in Hematopoietic Cells

Etsuro Ito, Tsutomu Toki

The Japanese Journal of Pediatric Hematology   10 ( 1 )   8 - 17   1996.2

Analysis of Clinical Characteristics on Infantile Leukemia.

ARAI Koji, TACHIBANA Naoki, TAKANO Nagakuni, WATANABE Arata, YOKOYAMA Shinkichi, IMAIZUMI Masue, KIKUTA Atsushi, TANAKA Atsushi, YOKOYAMA Masaru, ITO Etsuro, TOKI Tsutomu, TERUI Kiminori, ANZAI Yukiko, OKA Toshiaki, ISHIKAWA Yorikazu, KUDO Toru, TAKEDA Takeo

The Japanese Journal of Pediatric Hematology   10 ( 5 )   344 - 350   1996

Erythroid Transcription Factors in Hematopoietic Cells.

ITO Etsuro, TOKI Tsutomu

The Japanese Journal of Pediatric Hematology   10 ( 1 )   8 - 17   1996

Anemia in Children with Neurological Diseases: Influence of Antiepileptic Drugs

SHIOTANI Mutsuko, ONODERA Norio, TOKI Chikara, KANDORI Michiko, YOKOYAMA Masaru

The Hirosaki medical journal   46 ( 3 )   254 - 259   1995.2

Erythroid transcription factor GATA-1

Tsutomu Toki, Etsuro Ito

Hematology & Oncology   26 ( 3 )   227 - 233   1993.3