Updated on 2021/12/08

写真a

 
TANJI KUNIKAZU
 
Affiliation
Division of Medical Science Basic Medicine Section
Full-time staff
Graduate School of Medicine Institute for Brain Science Neuropathology

Degree

  • 博士(医学)

Research Areas

  • Life Science / Anatomy and histopathology of nervous system

Professional Memberships

  • 日本神経病理学会

  • 日本神経科学会

Papers

  • Accumulation of the sigma-1 receptor is common to neuronal nuclear inclusions in various neurodegenerative diseases.

    Yasuo Miki, Fumiaki Mori, Tomoya Kon, Kunikazu Tanji, Yasuko Toyoshima, Mari Yoshida, Hidenao Sasaki, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi

    Neuropathology : official journal of the Japanese Society of Neuropathology   34 ( 2 )   148 - 158   2014.4

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  • Novel tankyrase inhibitors suppress TDP-43 aggregate formation.

    Kunikazu Tanji, Fumiaki Mori, Fumiyuki Shirai, Takehiro Fukami, Hiroyuki Seimiya, Jun Utsumi, Akiyoshi Kakita, Koichi Wakabayashi

    Biochemical and biophysical research communications   537   85 - 92   2021.1

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  • Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice.

    Hiromi Yamazaki, Shuya Kasai, Junsei Mimura, Peng Ye, Atsushi Inose-Maruyama, Kunikazu Tanji, Koichi Wakabayashi, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, Tsubasa Sato, Taku Ozaki, Douglas R Cavener, Masayuki Yamamoto, Ken Itoh

    PLoS genetics   16 ( 4 )   e1008693 - e1008693   2020.4

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  • Nrp1 is Activated by Konjac Ceramide Binding-Induced Structural Rigidification of the a1a2 Domain.

    Seigo Usuki, Yoshiaki Yasutake, Noriko Tamura, Tomohiro Tamura, Kunikazu Tanji, Takashi Saitoh, Yuta Murai, Daisuke Mikami, Kohei Yuyama, Kenji Monde, Katsuyuki Mukai, Yasuyuki Igarashi

    Cells   9 ( 2 )   2020.2

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  • Effects of voluntary and forced exercises on motor function recovery in intracerebral hemorrhage rats.

    Chihiro Sato, Kunikazu Tanji, Shuji Shimoyama, Mitsuru Chiba, Misaki Mikami, Shuhei Koeda, Koshi Sumigawa, Kazuki Akahira, Junko Yamada

    Neuroreport   31 ( 2 )   189 - 196   2020.1

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  • Autophagy Is a Common Degradation Pathway for Bunina Bodies and TDP-43 Inclusions in Amyotrophic Lateral Sclerosis.

    Fumiaki Mori, Yasuo Miki, Tomoya Kon, Kunikazu Tanji, Koichi Wakabayashi

    Journal of neuropathology and experimental neurology   78 ( 10 )   910 - 921   2019.10

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  • Immunoreactivity of myelin-associated oligodendrocytic basic protein in Lewy bodies.

    Tomoya Kon, Kunikazu Tanji, Fumiaki Mori, Akari Kimura, Akiyoshi Kakita, Koichi Wakabayashi

    Neuropathology : official journal of the Japanese Society of Neuropathology   39 ( 4 )   279 - 285   2019.8

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  • Phosphorylated TDP-43 aggregates in skeletal and cardiac muscle are a marker of myogenic degeneration in amyotrophic lateral sclerosis and various conditions.

    Fumiaki Mori, Mari Tada, Tomoya Kon, Yasuo Miki, Kunikazu Tanji, Hidekachi Kurotaki, Masahiko Tomiyama, Tomohiko Ishihara, Osamu Onodera, Akiyoshi Kakita, Koichi Wakabayashi

    Acta neuropathologica communications   7 ( 1 )   165 - 165   2019.7

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  • Phosphorylated NUB1 distinguishes α-synuclein in Lewy bodies from that in glial cytoplasmic inclusions in multiple system atrophy.

    Kunikazu Tanji, Yasuo Miki, Fumiaki Mori, Tomoya Kon, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi

    Brain pathology (Zurich, Switzerland)   29 ( 6 )   803 - 812   2019.7

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  • Trehalose intake and exercise upregulate a glucose transporter, GLUT8, in the brain.

    Hidemi Narita, Kunikazu Tanji, Yasuo Miki, Fumiaki Mori, Koichi Wakabayashi

    Biochemical and biophysical research communications   514 ( 3 )   672 - 677   2019.6

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  • An autopsy case of early-stage amyotrophic lateral sclerosis with TDP-43 immunoreactive neuronal, but not glial, inclusions.

    Tomoya Kon, Fumiaki Mori, Yoshinobu Oyama, Kunikazu Tanji, Tamaki Kimura, Shirushi Takahashi, Koichi Wakabayashi

    Neuropathology : official journal of the Japanese Society of Neuropathology   39 ( 3 )   224 - 230   2019.6

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  • A mouse model of adult-onset multiple system atrophy.

    Kunikazu Tanji, Yasuo Miki, Fumiaki Mori, Yoshikazu Nikaido, Hidemi Narita, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi

    Neurobiology of disease   127   339 - 349   2019.4

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  • Neurite Outgrowth and Morphological Changes Induced by 8-trans Unsaturation of Sphingadienine in kCer Molecular Species.

    Seigo Usuki, Noriko Tamura, Tomohiro Tamura, Kunikazu Tanji, Daisuke Mikami, Katsuyuki Mukai, Yasuyuki Igarashi

    International journal of molecular sciences   20 ( 9 )   2019.4

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  • Atypical globular glial tauopathy with a combination of types I and II pathology.

    Tomoya Kon, Fumiaki Mori, Akira Arai, Yasuo Miki, Kunikazu Tanji, Hidekachi Kurotaki, Masahiko Tomiyama, Koichi Wakabayashi

    Neuropathology : official journal of the Japanese Society of Neuropathology   39 ( 2 )   127 - 134   2019.4

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  • Konjac ceramide (kCer) regulates keratinocyte migration by Sema3A-like repulsion mechanism.

    Seigo Usuki, Noriko Tamura, Tomohiro Tamura, Shigeki Higashiyama, Kunikazu Tanji, Susumu Mitsutake, Asuka Inoue, Junken Aoki, Katsuyuki Mukai, Yasuyuki Igarashi

    Biochemistry and biophysics reports   17   132 - 138   2019.3

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  • TRIM9 and TRIM67 Are New Targets in Paraneoplastic Cerebellar Degeneration.

    Le Duy Do, Stephanie L Gupton, Kunikazu Tanji, Joubert Bastien, Sabine Brugière, Yohann Couté, Isabelle Quadrio, Veronique Rogemond, Nicole Fabien, Virginie Desestret, Jerome Honnorat

    Cerebellum (London, England)   2018.10

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  • Colocalization of Bunina bodies and TDP-43 inclusions in a case of sporadic amyotrophic lateral sclerosis with Lewy body-like hyaline inclusions.

    Yasuo Miki, Fumiaki Mori, Yusuke Seino, Kunikazu Tanji, Tadashi Yoshizawa, Hiroshi Kijima, Mikio Shoji, Koichi Wakabayashi

    Neuropathology : official journal of the Japanese Society of Neuropathology   38 ( 5 )   521 - 528   2018.10

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  • Autophagy mediators (FOXO1, SESN3 and TSC2) in Lewy body disease and aging.

    Yasuo Miki, Kunikazu Tanji, Fumiaki Mori, Jun Utsumi, Hidenao Sasaki, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi

    Neuroscience letters   684   35 - 41   2018.9

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  • Gnetin C, a resveratrol dimer, reduces amyloid-β 1-42 (Aβ42) production and ameliorates Aβ42-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells.

    Syota Seino, Takeru Kimoto, Hidemi Yoshida, Kunikazu Tanji, Tomoh Matsumiya, Ryo Hayakari, Kazuhiko Seya, Shogo Kawaguchi, Kazushi Tsuruga, Hiroshi Tanaka, Tadaatsu Imaizumi

    Biomedical research (Tokyo, Japan)   39 ( 3 )   105 - 115   2018.6

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  • YOD1 attenuates neurogenic proteotoxicity through its deubiquitinating activity.

    Kunikazu Tanji, Fumiaki Mori, Yasuo Miki, Jun Utsumi, Hidenao Sasaki, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi

    Neurobiology of disease   112   14 - 23   2018.4

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  • Alteration of autophagy-related proteins in peripheral blood mononuclear cells of patients with Parkinson's disease.

    Yasuo Miki, Shuji Shimoyama, Tomoya Kon, Tatsuya Ueno, Ryo Hayakari, Kunikazu Tanji, Tomoh Matsumiya, Eiki Tsushima, Fumiaki Mori, Koichi Wakabayashi, Masahiko Tomiyama

    Neurobiology of aging   63   33 - 43   2018.3

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  • Immunohistochemical localization of exoribonucleases (DIS3L2 and XRN1) in intranuclear inclusion body disease.

    Fumiaki Mori, Kunikazu Tanji, Yasuo Miki, Yasuko Toyoshima, Hidenao Sasaki, Mari Yoshida, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi

    Neuroscience letters   662   389 - 394   2018.1

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  • Status epilepticus causing extensive microvacuolar change with astrocytosis and diffusion MRI abnormalities in the subcortical white matter.

    Yasuo Miki, Kunikazu Tanji, Kensuke Kimura, Nobuhisa Yajima, Fumiaki Mori, Koichi Wakabayashi

    Journal of the neurological sciences   382   55 - 57   2017.11

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  • Rebamipide reduces amyloid-β 1-42 (Aβ42) production and ameliorates Aβ43-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells.

    Kenta Fukui, Kazuma Yachi, Hidemi Yoshida, Kunikazu Tanji, Tomoh Matsumiya, Ryo Hayakari, Kazushi Tsuruga, Hiroshi Tanaka, Tadaatsu Imaizumi

    Neuroscience research   124   40 - 50   2017.11

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  • Alteration of mitochondrial protein PDHA1 in Lewy body disease and PARK14.

    Yasuo Miki, Kunikazu Tanji, Fumiaki Mori, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi

    Biochemical and biophysical research communications   489 ( 4 )   439 - 444   2017.6

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  • PLA2G6 accumulates in Lewy bodies in PARK14 and idiopathic Parkinson's disease.

    Yasuo Miki, Kunikazu Tanji, Fumiaki Mori, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi

    Neuroscience letters   645   40 - 45   2017.4

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  • Interferon (IFN)-induced protein 35 (IFI35) negatively regulates IFN-β-phosphorylated STAT1-RIG-I-CXCL10/CCL5 axis in U373MG astrocytoma cells treated with polyinosinic-polycytidylic acid.

    Kyogo Shirai, Taku Shimada, Hidemi Yoshida, Ryo Hayakari, Tomoh Matsumiya, Kunikazu Tanji, Manabu Murakami, Hiroshi Tanaka, Tadaatsu Imaizumi

    Brain research   1658   60 - 67   2017.3

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  • AMBRA1, a novel α-synuclein-binding protein, is implicated in the pathogenesis of multiple system atrophy.

    Yasuo Miki, Kunikazu Tanji, Fumiaki Mori, Yota Tatara, Jun Utsumi, Hidenao Sasaki, Akiyoshi Kakita, Hitoshi Takahashi, Gian Maria Fimia, Koichi Wakabayashi

    Brain pathology (Zurich, Switzerland)   2016.11

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  • Novel eosinophilic neuronal cytoplasmic inclusions in the external cuneate nucleus of humans.

    Masako Ito, Keiko Nakamura, Fumiaki Mori, Yasuo Miki, Kunikazu Tanji, Koichi Wakabayashi

    Neuropathology : official journal of the Japanese Society of Neuropathology   2016.3

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  • The role of NUB1 in α-synuclein degradation in Lewy body disease model mice.

    Kunikazu Tanji, Yasuo Miki, Atsushi Maruyama, Fumiaki Mori, Junsei Mimura, Ken Itoh, Tetsu Kamitani, Koichi Wakabayashi

    Biochemical and biophysical research communications   470 ( 3 )   635 - 642   2016.2

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  • G protein-coupled receptor 26 immunoreactivity in intranuclear inclusions associated with polyglutamine and intranuclear inclusion body diseases.

    Fumiaki Mori, Kunikazu Tanji, Yasuo Miki, Yasuko Toyoshima, Mari Yoshida, Akiyoshi Kakita, Hitoshi Takahashi, Jun Utsumi, Hidenao Sasaki, Koichi Wakabayashi

    Neuropathology : official journal of the Japanese Society of Neuropathology   36 ( 1 )   50 - 55   2016.2

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  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

    Daniel J Klionsky, Kotb Abdelmohsen, Kunikazu Tanji, Susu M Zughaier

    Autophagy   12 ( 1 )   1 - 222   2016.1

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  • Retinoic acid-inducible gene-I-like receptor (RLR)-mediated antiviral innate immune responses in the lower respiratory tract: Roles of TRAF3 and TRAF5.

    Yuki Chiba, Tomoh Matsumiya, Tsugumi Satoh, Ryo Hayakari, Ken Furudate, Fei Xing, Hidemi Yoshida, Kunikazu Tanji, Hiroki Mizukami, Tadaatsu Imaizumi, Etsuro Ito

    Biochemical and biophysical research communications   467 ( 2 )   191 - 196   2015.11

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  • α-Synuclein pathology in the cranial and spinal nerves in Lewy body disease.

    Keiko Nakamura, Fumiaki Mori, Kunikazu Tanji, Yasuo Miki, Yasuko Toyoshima, Akiyoshi Kakita, Hitoshi Takahashi, Masahito Yamada, Koichi Wakabayashi

    Neuropathology : official journal of the Japanese Society of Neuropathology   2015.11

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  • Sortilin-related receptor CNS expressed 2 (SorCS2) is localized to Bunina bodies in amyotrophic lateral sclerosis.

    Fumiaki Mori, Yasuo Miki, Kunikazu Tanji, Akiyoshi Kakita, Hitoshi Takahashi, Jun Utsumi, Hidenao Sasaki, Koichi Wakabayashi

    Neuroscience letters   608   6 - 11   2015.11

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  • Trehalose intake induces chaperone molecules along with autophagy in a mouse model of Lewy body disease.

    Kunikazu Tanji, Yasuo Miki, Atsushi Maruyama, Junsei Mimura, Tomoh Matsumiya, Fumiaki Mori, Tadaatsu Imaizumi, Ken Itoh, Koichi Wakabayashi

    Biochemical and biophysical research communications   465 ( 4 )   746 - 752   2015.10

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  • Interferon-stimulated gene (ISG) 60, as well as ISG56 and ISG54, positively regulates TLR3/IFN-β/STAT1 axis in U373MG human astrocytoma cells.

    Tadaatsu Imaizumi, Hidemi Yoshida, Ryo Hayakari, Fei Xing, Lian Wang, Tomoh Matsumiya, Kunikazu Tanji, Shogo Kawaguchi, Manabu Murakami, Hiroshi Tanaka

    Neuroscience research   2015.9

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  • Accumulation of phosphorylated α-synuclein in subpial and periventricular astrocytes in multiple system atrophy of long duration.

    Keiko Nakamura, Fumiaki Mori, Tomoya Kon, Kunikazu Tanji, Yasuo Miki, Masahiko Tomiyama, Hidekachi Kurotaki, Yasuko Toyoshima, Akiyoshi Kakita, Hitoshi Takahashi, Masahito Yamada, Koichi Wakabayashi

    Neuropathology : official journal of the Japanese Society of Neuropathology   2015.8

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  • Alteration of Upstream Autophagy-Related Proteins (ULK1, ULK2, Beclin1, VPS34 and AMBRA1) in Lewy Body Disease.

    Yasuo Miki, Kunikazu Tanji, Fumiaki Mori, Jun Utsumi, Hidenao Sasaki, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi

    Brain pathology (Zurich, Switzerland)   2015.8

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  • Localization of nuclear receptor subfamily 4, group A, member 3 (NR4A3) in Lewy body disease and multiple system atrophy.

    Tomoya Kon, Yasuo Miki, Kunikazu Tanji, Fumiaki Mori, Masahiko Tomiyama, Yasuko Toyoshima, Akiyoshi Kakita, Hitoshi Takahashi, Jun Utsumi, Hidenao Sasaki, Koichi Wakabayashi

    Neuropathology : official journal of the Japanese Society of Neuropathology   2015.6

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  • An autopsy case of refractory epilepsy due to unilateral polymicrogyria in a 65-year-old man: Histogenesis of four-layered polymicrogyric cortex.

    Yasuo Miki, Kunikazu Tanji, Fumiaki Mori, Namiko Sakamoto, Koichi Wakabayashi

    Neuropathology : official journal of the Japanese Society of Neuropathology   2015.6

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  • Isopentenyl diphosphate isomerase, a cholesterol synthesizing enzyme, is localized in Lewy bodies.

    Keiko Nakamura, Fumiaki Mori, Kunikazu Tanji, Yasuo Miki, Masahito Yamada, Akiyoshi Kakita, Hitoshi Takahashi, Jun Utsumi, Hidenao Sasaki, Koichi Wakabayashi

    Neuropathology : official journal of the Japanese Society of Neuropathology   2015.5

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  • Carnosic acid attenuates apoptosis induced by amyloid-β 1-42 or 1-43 in SH-SY5Y human neuroblastoma cells.

    Pengfei Meng, Hidemi Yoshida, Kunikazu Tanji, Tomoh Matsumiya, Fei Xing, Ryo Hayakari, Liang Wang, Kazushi Tsuruga, Hiroshi Tanaka, Junsei Mimura, Kunio Kosaka, Ken Itoh, Ippei Takahashi, Shogo Kawaguchi, Tadaatsu Imaizumi

    Neuroscience research   94   1 - 9   2015.5

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  • Desferrioxamine, an iron chelator, inhibits CXCL10 expression induced by polyinosinic-polycytidylic acid in U373MG human astrocytoma cells.

    Tadaatsu Imaizumi, Nina Sakashita, Yasuaki Mushiga, Hidemi Yoshida, Ryo Hayakari, Fei Xing, Liang Wang, Tomoh Matsumiya, Kunikazu Tanji, Yuki Chiba, Ken Furudate, Shogo Kawaguchi, Manabu Murakami, Hiroshi Tanaka

    Neuroscience research   94   10 - 16   2015.5

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  • Role of the Keap1/Nrf2 pathway in neurodegenerative diseases.

    Hiromi Yamazaki, Kunikazu Tanji, Koichi Wakabayashi, Shin Matsuura, Ken Itoh

    Pathology international   65 ( 5 )   210 - 219   2015.5

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  • Sigma-1 receptor is involved in degradation of intranuclear inclusions in a cellular model of Huntington's disease.

    Yasuo Miki, Kunikazu Tanji, Fumiaki Mori, Koichi Wakabayashi

    Neurobiology of disease   74   25 - 31   2015.2

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  • Filamentous aggregations of phosphorylated α-synuclein in Schwann cells (Schwann cell cytoplasmic inclusions) in multiple system atrophy.

    Keiko Nakamura, Fumiaki Mori, Tomoya Kon, Kunikazu Tanji, Yasuo Miki, Masahiko Tomiyama, Hidekachi Kurotaki, Yasuko Toyoshima, Akiyoshi Kakita, Hitoshi Takahashi, Masahito Yamada, Koichi Wakabayashi

    Acta neuropathologica communications   3   29 - 29   2015

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  • p62 Deficiency Enhances α-Synuclein Pathology in Mice.

    Kunikazu Tanji, Saori Odagiri, Yasuo Miki, Atsushi Maruyama, Yoshikazu Nikaido, Junsei Mimura, Fumiaki Mori, Eiji Warabi, Toru Yanagawa, Shinya Ueno, Ken Itoh, Koichi Wakabayashi

    Brain pathology (Zurich, Switzerland)   2014.10

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  • An autopsy case of incipient Pick's disease: Immunohistochemical profile of early-stage Pick body formation.

    Yasuo Miki, Fumiaki Mori, Kunikazu Tanji, Hidekachi Kurotaki, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi

    Neuropathology : official journal of the Japanese Society of Neuropathology   34 ( 4 )   386 - 391   2014.8

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  • Phosphorylation of serine 349 of p62 in Alzheimer's disease brain.

    Kunikazu Tanji, Yasuo Miki, Taku Ozaki, Atsushi Maruyama, Hidemi Yoshida, Junsei Mimura, Tomoh Matsumiya, Fumiaki Mori, Tadaatsu Imaizumi, Ken Itoh, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi

    Acta neuropathologica communications   2   50 - 50   2014.6

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  • Ubiquitin-negative, eosinophilic neuronal cytoplasmic inclusions associated with stress granules and autophagy: an immunohistochemical investigation of two cases.

    Fumiaki Mori, Yuka Watanabe, Yasuo Miki, Kunikazu Tanji, Saori Odagiri, Komyo Eto, Koichi Wakabayashi

    Neuropathology : official journal of the Japanese Society of Neuropathology   34 ( 2 )   140 - 147   2014.4

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  • ISG54 and ISG56 are induced by TLR3 signaling in U373MG human astrocytoma cells: Possible involvement in CXCL10 expression.

    Tadaatsu Imaizumi, Akiko Numata, Chikashi Yano, Hidemi Yoshida, Pengfei Meng, Ryo Hayakari, Fei Xing, Lian Wang, Tomoh Matsumiya, Kunikazu Tanji, Tetsuya Tatsuta, Manabu Murakami, Hiroshi Tanaka

    Neuroscience research   2014.3

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  • Carnosic acid suppresses the production of amyloid-β 1-42 and 1-43 by inducing an α-secretase TACE/ADAM17 in U373MG human astrocytoma cells.

    Hidemi Yoshida, Pengfei Meng, Tomoh Matsumiya, Kunikazu Tanji, Ryo Hayakari, Fei Xing, Liang Wang, Kazushi Tsuruga, Hiroshi Tanaka, Junsei Mimura, Kunio Kosaka, Ken Itoh, Ippei Takahashi, Tadaatsu Imaizumi

    Neuroscience research   79   83 - 93   2014.2

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  • ALS-associated protein FIG4 is localized in Pick and Lewy bodies, and also neuronal nuclear inclusions, in polyglutamine and intranuclear inclusion body diseases.

    Tomoya Kon, Fumiaki Mori, Kunikazu Tanji, Yasuo Miki, Yasuko Toyoshima, Mari Yoshida, Hidenao Sasaki, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi

    Neuropathology : official journal of the Japanese Society of Neuropathology   34 ( 1 )   19 - 26   2014.2

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  • [Multiple system atrophy and autophagy].

    Koichi Wakabayashi, Kunikazu Tanji

    Rinshō shinkeigaku = Clinical neurology   54 ( 12 )   966 - 968   2014

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  • Valosin-containing protein immunoreactivity in tauopathies, synucleinopathies, polyglutamine diseases and intranuclear inclusion body disease.

    Fumiaki Mori, Kunikazu Tanji, Yasuko Toyoshima, Hidenao Sasaki, Mari Yoshida, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi

    Neuropathology : official journal of the Japanese Society of Neuropathology   33 ( 6 )   637 - 644   2013.12

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  • Giant cell polymyositis and myocarditis associated with myasthenia gravis and thymoma.

    Tomoya Kon, Fumiaki Mori, Kunikazu Tanji, Yasuo Miki, Tamaki Kimura, Koichi Wakabayashi

    Neuropathology : official journal of the Japanese Society of Neuropathology   33 ( 3 )   281 - 287   2013.6

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  • The Lewy body in Parkinson's disease and related neurodegenerative disorders.

    Koichi Wakabayashi, Kunikazu Tanji, Saori Odagiri, Yasuo Miki, Fumiaki Mori, Hitoshi Takahashi

    Molecular neurobiology   47 ( 2 )   495 - 508   2013.4

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    Language:English   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Carnosic acid suppresses the production of amyloid-β 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells.

    Pengfei Meng, Hidemi Yoshida, Tomoh Matsumiya, Tadaatsu Imaizumi, Kunikazu Tanji, Fei Xing, Ryo Hayakari, Junichi Dempoya, Tetsuya Tatsuta, Tomomi Aizawa-Yashiro, Junsei Mimura, Kunio Kosaka, Ken Itoh, Kei Satoh

    Neuroscience research   75 ( 2 )   94 - 102   2013.2

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  • Brain expression level and activity of HDAC6 protein in neurodegenerative dementia.

    Saori Odagiri, Kunikazu Tanji, Fumiaki Mori, Yasuo Miki, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi

    Biochemical and biophysical research communications   430 ( 1 )   394 - 399   2013.1

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  • Keap1 is localized in neuronal and glial cytoplasmic inclusions in various neurodegenerative diseases.

    Kunikazu Tanji, Atsushi Maruyama, Saori Odagiri, Fumiaki Mori, Ken Itoh, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi

    Journal of neuropathology and experimental neurology   72 ( 1 )   18 - 28   2013.1

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  • Endosomal sorting related protein CHMP2B is localized in Lewy bodies and glial cytoplasmic inclusions in α-synucleinopathy.

    Satoshi Tanikawa, Fumiaki Mori, Kunikazu Tanji, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi

    Neuroscience letters   527 ( 1 )   16 - 21   2012.10

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  • Alteration of autophagosomal proteins in the brain of multiple system atrophy.

    Kunikazu Tanji, Saori Odagiri, Atsushi Maruyama, Fumiaki Mori, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi

    Neurobiology of disease   49C   190 - 198   2012.8

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  • Autophagy-related proteins (p62, NBR1 and LC3) in intranuclear inclusions in neurodegenerative diseases

    Mori, F.,Tanji, K.,Odagiri, S.,Toyoshima, Y.,Yoshida, M.,Kakita, A.,Takahashi, H.,Wakabayashi, K.

    Neurosci Lett   522 ( 2 )   134 - 138   2012.6

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  • p62/sequestosome 1 binds to TDP-43 in brains with frontotemporal lobar degeneration with TDP-43 inclusions

    Tanji K, Zhang HX, Mori F, Kakita A, Takahashi H, Wakabayashi K

    Jounal of Neuroscience Research   90 ( 10 )   2034 - 2042   2012.6

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  • Ubiquilin immunoreactivity in cytoplasmic and nuclear inclusions in synucleinopathies, polyglutamine diseases and intranuclear inclusion body disease

    Mori, F.,Tanji, K.,Odagiri, S.,Toyoshima, Y.,Yoshida, M.,Ikeda, T.,Sasaki, H.,Kakita, A.,Takahashi, H.,Wakabayashi, K.

    Acta Neuropathologica   124 ( 1 )   149 - 151   2012.6

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  • Ubiquitin-related proteins in neuronal and glial intranuclear inclusions in intranuclear inclusion body disease

    Mori, F.,Tanji, K.,Odagiri, S.,Hattori, M.,Hoshikawa, Y.,Kono, C.,Yasui, K.,Yokoi, S.,Hasegawa, Y.,Kamitani, T.,Yoshida, M.,Wakabayashi, K.

    Pathol Int   62 ( 6 )   407 - 411   2012.5

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  • Autophagic adapter protein NBR1 is localized in Lewy bodies and glial cytoplasmic inclusions and is involved in aggregate formation in alpha-synucleinopathy

    Odagiri, S.,Tanji K., Mori, F.,Kakita, A.,Takahashi H.,Wakabayashi K.

    Acta Neuropathologica   124 ( 2 )   173 - 186   2012.4

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  • Optineurin immunoreactivity in neuronal nuclear inclusions of polyglutamine diseases (Huntington's, DRPLA, SCA2, SCA3) and intranuclear inclusion body disease

    Mori, F.,Tanji, K.,Toyoshima, Y.,Yoshida, M.,Kakita, A.,Takahashi, H.,Wakabayashi, K.

    Acta Neuropathologica   123 ( 5 )   747 - 749   2012.2

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  • Immunohistochemical analysis of Marinesco bodies, using antibodies against proteins implicated in the ubiquitin-proteasome system, autophagy and aggresome formation

    Odagiri, S.,Tanji, K.,Mori, F.,Kakita, A.,Takahashi, H.,Kamitani, T.,Wakabayashi, K.

    Neuropathology   32 ( 3 )   261 - 266   2011.11

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  • Immunohistochemical study of microscopic globular bodies of normal human brain

    Odagiri, S.,Mori, F.,Tanji, K.,Kuroda, N.,Wakabayashi, K.

    Biomedical Research   32 ( 5 )   337 - 342   2011.10

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  • Status epilepticus associated with extensive axonal swelling in the unilateral cerebral cortex and hippocampus

    Mori, F.,Tanji, K.,Miki, Y.,Nishijima, H.,Baba, M.,Kurotaki, H.,Wakabayashi, K.

    Neuropathol Appl Neurobiol   38 ( 4 )   387 - 390   2011.10

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  • Synphilin-1-Binding Protein NUB1 is Colocalized With Nonfibrillar, Proteinase K-Resistant alpha-Synuclein in Presynapses in Lewy Body Disease

    Tanji K, Mori F, Kito K, Kakita A, Mimura J, Itoh K, Takahashi H, Kamitani T, Wakabayashi K

    Journal of Neuropathology & Experimental Neurology   70 ( 10 )   879 - 889   2011.9

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  • FUS immunoreactivity of neuronal and glial intranuclear inclusions in intranuclear inclusion body disease

    Mori, F.,Tanji, K.,Kon, T.,Odagiri, S.,Hattori, M.,Hoshikawa, Y.,Kono, C.,Yasui, K.,Yokoi, S.,Hasegawa, Y.,Yoshida, M.,Wakabayashi, K.

    Neuropathol Appl Neurobiol   38 ( 4 )   322 - 328   2011.9

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  • Abnormal tau deposition in neurons, but not in glial cells in the cerebral tissue surrounding arteriovenous malformation

    Kon, T.,Mori, F.,Tanji, K.,Miki, Y.,Tomiyama, M.,Baba, M.,Umehara, Y.,Kurotaki, H.,Wakabayashi, K.

    Neuropathology   32 ( 3 )   267 - 271   2011.8

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  • Alteration of autophagosomal proteins (LC3, GABARAP and GATE-16) in Lewy body disease

    Tanji K, Mori F, Kakita A, Takahashi H, Wakabayashi K

    Neurobiology of disease   43 ( 3 )   690 - 697   2011.6

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  • Accumulation of histone deacetylase 6, an aggresome-related protein, is specific to Lewy bodies and glial cytoplasmic inclusions

    Miki, Y.,Mori, F.,Tanji, K.,Kakita, A.,Takahashi H.,Wakabayashi, K.

    Neuropathology   31 ( 6 )   561 - 568   2011.2

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  • Edaravone and carnosic acid synergistically enhance the expression of nerve growth factor in human astrocytes under hypoxia/reoxygenation

    Yoshida, H.,Mimura, J.,Imaizumi, T.,Matsumiya, T.,Ishikawa, A.,Metoki, N.,Tanji, K., et al

    Neuroscience Research   69 ( 4 )   291 - 298   2011.1

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  • Enhancement of native and phosphorylated TDP-43 immunoreactivity by proteinase K treatment following autoclave heating

    Mori, F.,Tanji, K.,Kakita, A.,Takahashi, H.,Wakabayashi, K.

    Neuropathology   31 ( 4 )   401 - 404   2010.12

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  • Proteinase K-resistant alpha-synuclein is deposited in presynapses in human Lewy body disease and A53T alpha-synuclein transgenic mice. Acta Neuropathol, 120: 145-154, 2010.

    Tanji, K., Mori, F., Mimura, J., Itoh, K., Kakita, A., Takahashi, H. & Wakabayashi, K.

    Acta Neuropathologica   120 ( 2 )   145 - 154   2010.8

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  • Incipient intranuclear inclusion body disease in a 78-year-old woman

    Mori, F.,Miki, Y.,Tanji, K.,Ogura, E.,Yagihashi, N.,Jensen, P. H.,Wakabayashi, K.

    Neuropathology   31 ( 2 )   188 - 193   2010.7

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  • Alteration of biochemical and pathological properties of TDP-43 protein by a lipid mediator, 15-deoxy-Delta(12,14)-prostaglandin J(2).

    Hai-Xin Zhang, Kunikazu Tanji, Hidemi Yoshida, Makoto Hayakari, Takahiro Shibata, Fumiaki Mori, Koji Uchida, Koichi Wakabayashi

    Experimental neurology   222 ( 2 )   296 - 303   2010.4

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  • TRIM9, a novel brain-specific E3 ubiquitin ligase, is repressed in the brain of Parkinson's disease and dementia with Lewy bodies

    Tanji, K.,Kamitani, T.,Mori, F.,Kakita, A.,Takahashi, H.,Wakabayashi, K.

    Neurobiology of disease   38 ( 2 )   210 - 217   2010.1

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  • Epitope mapping of 2E2-D3, a monoclonal antibody directed against human TDP-43.

    Hai-Xin Zhang, Kunikazu Tanji, Fumiaki Mori, Koichi Wakabayashi

    Neuroscience letters   434 ( 2 )   170 - 174   2008.3

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  • Immunohistochemical localization of NUB1, a synphilin-1-binding protein, in neurodegenerative disorders.

    Tanji K, Mori F, Kakita A, Zhang H, Kito K, Kamitani T, Takahashi H, Wakabayashi K

    Acta Neuropathol   114 ( 4 )   365 - 371   2007.10

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Books

  • かぐわしき植物たちの秘密 香りとヒトの科学

    丹治邦和, 田中修( Role: Joint author)

    山と渓谷社  2021.3 

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    Language:Japanese Book type:General book, introductory book for general audience

  • 植物はなぜ毒があるのか 草・木・花のしたたかな生存戦略.

    丹治邦和, 田中修( Role: Joint author)

    幻冬舎新書  2020.4 

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    Language:Japanese Book type:General book, introductory book for general audience

  • Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

    Tanji K, Mori F, Wakabayashi K.( Role: Joint author)

    Elsevier  2013.9 

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    Language:English Book type:Scholarly book

Review Papers

  • Role of the ISR-ATF4 pathway and its cross talk with Nrf2 in mitochondrial quality control

    Kasai, S. Yamazaki, H. Tanji, K. Engler, M. J. Matsumiya, T. Itoh, K.

    J Clin Biochem Nutr   64 ( 1 )   1 - 12   2019.2

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  • Emerging functional cross-talk between the Keap1-Nrf2 system and mitochondria

    Itoh, K. Ye, P. Matsumiya, T. Tanji, K. Ozaki, T.

    J Clin Biochem Nutr   2015.3

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  • Role of the Keap1/Nrf2 pathway in neurodegenerative diseases

    Yamazaki, H. Tanji, K. Wakabayashi, K. Matsuura, S. Itoh, K.

    Pathol Int   2015.2

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Awards

  • 第36回唐牛記念医学研究基金(助成金A)

    2018.01

  • 弘前大学医学部学術特別賞

    2012.01