論文 - 今泉 忠淳
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Chloroquine attenuates TLR3-mediated plasminogen activator inhibitor-1 expression in cultured human glomerular endothelial cells.
Tomomi Aizawa, Tadaatsu Imaizumi, Koji Hirono, Shojiro Watanabe, Koji Tsugawa, Hiroshi Tanaka
Clinical and experimental nephrology 2018年10月
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Gnetin C suppresses double-stranded RNA-induced C-C motif chemokine ligand 2 (CCL2) and CCL5 production by inhibiting Toll-like receptor 3 signaling pathway.
Hidemi Yoshida, Tadaatsu Imaizumi, Tomoh Matsumiya, Kazuhiko Seya, Shogo Kawaguchi, Hiroshi Tanaka
Biomedical research (Tokyo, Japan) 39 ( 5 ) 231 - 240 2018年10月
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The Essential Role of Double-Stranded RNA-Dependent Antiviral Signaling in the Degradation of Nonself Single-Stranded RNA in Nonimmune Cells.
Sayaka Kimura, Tomoh Matsumiya, Yuko Shiba, Michi Nakanishi, Ryo Hayakari, Shogo Kawaguchi, Hidemi Yoshida, Tadaatsu Imaizumi
Journal of immunology (Baltimore, Md. : 1950) 201 ( 3 ) 1044 - 1052 2018年08月
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Retinoic acid-inducible gene-I, melanoma differentiation-associated gene 5 and CXCL10 are induced by a TLR3 agonist in human brain microvascular endothelial cells.
Imaizumi T, Arai A, Kawaguchi S, Hayakari R, Matsumiya T, Seya K, Yoshida H, Tanaka H.
clinical and experimental neuroimmunology 9 189 - 97 2018年08月
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Gnetin C, a resveratrol dimer, reduces amyloid-β 1-42 (Aβ42) production and ameliorates Aβ42-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells.
Syota Seino, Takeru Kimoto, Hidemi Yoshida, Kunikazu Tanji, Tomoh Matsumiya, Ryo Hayakari, Kazuhiko Seya, Shogo Kawaguchi, Kazushi Tsuruga, Hiroshi Tanaka, Tadaatsu Imaizumi
Biomedical research (Tokyo, Japan) 39 ( 3 ) 105 - 115 2018年06月
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Matrix Gla protein negatively regulates calcification of human aortic valve interstitial cells isolated from calcified aortic valves.
Mari Chiyoya, Kazuhiko Seya, Zaiqiang Yu, Kazuyuki Daitoku, Shigeru Motomura, Tadaatsu Imaizumi, Ikuo Fukuda, Ken-Ichi Furukawa
Journal of pharmacological sciences 136 ( 4 ) 257 - 265 2018年04月
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Toll-Like Receptor 3 Signaling Contributes to Regional Neutrophil Recruitment in Cultured Human Glomerular Endothelial Cells.
Qiang Liu, Tadaatsu Imaizumi, Shogo Kawaguchi, Tomomi Aizawa, Tomoh Matsumiya, Shojiro Watanabe, Koji Tsugawa, Hidemi Yoshida, Kazushi Tsuruga, Kensuke Joh, Hiroshi Kijima, Hiroshi Tanaka
Nephron 139 ( 4 ) 349 - 358 2018年
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Expression of CCL5 is induced by polyinosinic-polycytidylic acid in cultured hCMEC/D3 human brain microvascular endothelial cells
Arai A, Imaizumi T, et al.
Clinical and Experimental Neuroimmunology 2017年10月
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DEC1 negatively regulates the expression of CXCL10 and CCL5 induced by poly IC in normal human mesangial cells.
Liu Q, Imaizumi T., et al
Biomedical Research 2017年08月
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DEC1 promotes hypoxia-induced epithelial-mesenchymal transition (EMT) in human hepatocellular carcinoma cells.
Murakami K, Imaizumi T., et al.
Biomedical Research 2017年08月
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Cylindromatosis (CYLD), a deubiquitinase, attenuates inflammatory signaling pathway by activating Toll-like receptor 3 in human mesangial cells.
Imaizumi T, Hayakari Y., et al.
Kidney & blood pressure research 2017年08月
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CCL5 is induced by TLR3 signaling in HuCCT1 human bile duct carcinoma cells: possible involvement in the pathogenesis of biliary atresia.
Shimada T, Imaizumi T, et al
Biomedical Research 2017年08月
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Urinary excretion of SMPDL-3b in children with intractable nephrotic syndrome.
Watanabe S, Imaizumi T., et al
Pediatrics international 2017年07月
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Rebamipide reduces amyloid-β 1–42 (Aβ42) production and ameliorates Aβ43-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells.
Fukui K., Imaizumi T., et al
Neuroscience research 2017年06月
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Clarithromycin attenuates the expression of monocyte chemoattractant protein-1 by activating toll-like receptor 4 in human mesangial cells.
Koji Tsugawa, Tadaatsu Imaizumi, Shojiro Watanabe, Kazushi Tsuruga, Hidemi Yoshida, Hiroshi Tanaka
Clinical and experimental nephrology 2017年04月
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Simultaneous measurement of adenosine 3’,5’-cyclic monophosphate and guanosine 3’,5’-cyclic monophosphate in biological samples.
Seya K., Imaizumi T., et al.
Hirosaki Medical Journal 2017年04月
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Interferon (IFN)-induced protein 35 (IFI35) negatively regulates IFN-β-phosphorylated STAT1-RIG-I-CXCL10/CCL5 axis in U373MG astrocytoma cells treated with polyinosinic-polycytidylic acid.
Kyogo Shirai, Taku Shimada, Hidemi Yoshida, Ryo Hayakari, Tomoh Matsumiya, Kunikazu Tanji, Manabu Murakami, Hiroshi Tanaka, Tadaatsu Imaizumi
Brain research 1658 60 - 67 2017年03月
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Chloroquine attenuates TLR3/IFN-β signaling in cultured normal human mesangial cells: A possible protective effect against renal damage in lupus nephritis.
Tadaatsu Imaizumi, Ryo Hayakari, Tomoh Matsumiya, Hidemi Yoshida, Kazushi Tsuruga, Shojiro Watanabe, Shogo Kawaguchi, Hiroshi Tanaka
Modern rheumatology 1 - 18 2017年02月
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Regression of atherosclerosis with apple procyanidins by activating the ATP-binding cassette subfamily A member 1 in a rabbit model.
Liang Wang, Toshio Fumoto, Saeko Masumoto, Toshihiko Shoji, Tomisato Miura, Masato Naraoka, Naoya Matsuda, Tadaatsu Imaizumi, Hiroki Ohkuma
Atherosclerosis 258 56 - 64 2017年01月
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Critical Role of IRF-3 in the Direct Regulation of dsRNA-Induced Retinoic Acid-Inducible Gene-I (RIG-I) Expression.
Ryo Hayakari, Tomoh Matsumiya, Fei Xing, Hidemi Yoshida, Makoto Hayakari, Tadaatsu Imaizumi
PloS one 11 ( 9 ) e0163520 - e0163520 2016年09月