ライフサイエンス / 外科系歯学

ライフサイエンス / 膠原病、アレルギー内科学

ライフサイエンス / 人体病理学

日本免疫学会

米国免疫学会

日本歯周病学会

アメリカ免疫学会

日本口腔外科学会

日本総合歯科学会

日本神経科学会

日本生化学会

日本口腔外科学会

日本免疫学会

アメリカ微生物学会

Effect of bisphosphonate alendronate on ERK-dependent growth in human gingival fibroblasts

Akiyama Natsumi, Kubota Kosei, Komatsu Shotaro, Itoh Ryohei, Chang Hao Chi, Yamazaki Shunya, Imaizumi Tadaatsu, Matsumiya Tomoh, Kobayashi Wataru

2023年03月

The double-stranded RNA-dependent protein kinase PKR negatively regulates the protein expression of IFN-β induced by RIG-I signaling.

Matsumiya T, Shiba Y, Ding J, Kawaguchi S, Seya K, Imaizumi T

FASEB journal : official publication of the Federation of American Societies for Experimental Biology   37 ( 2 )   e22780   2023年02月

Tryptanthrin attenuates TLR3-mediated STAT1 activation in THP-1 cells.

Numao N, Kawaguchi S, Ding J, Karasawa T, Seya K, Matsumiya T, Kikuchi H, Sakuraba H, Fukuda S, Imaizumi T

Immunologic research   70 ( 5 )   688 - 697   2022年10月

Porphyromonas gingivalis lipopolysaccharide induces interleukin-6 and c-c motif chemokine ligand 2 expression in cultured hCMEC/D3 human brain microvascular endothelial cells

Sato N, Matsumoto T, Kawaguchi S, Seya K, Matsumiya T, Ding J, Aizawa T, Imaizumi T.

2022年06月

大動脈弁狭窄症の弁石灰化に寄与する大動脈弁間質細胞の性状解析

于 在強, 劉 旭, 大徳 和之, 松宮 朋穂, 今泉 忠淳, 福田 幾夫, 瀬谷 和彦

弘前医学   72 ( 1-4 )   96   2022年

Expression of Zinc-Finger Antiviral Protein in hCMEC/D3 Human Cerebral Microvascular Endothelial Cells: Effect of a Toll-Like Receptor 3 Agonist.

Okudera M, Odawara M, Arakawa M, Kawaguchi S, Seya K, Matsumiya T, Sato R, Ding J, Morita E, Imaizumi T

Neuroimmunomodulation   29 ( 4 )   1 - 10   2021年12月

Inhibitory effect of anti-malarial agents on the expression of proinflammatory chemokines via Toll-like receptor 3 signaling in human glomerular endothelial cells.

Sato R, Imaizumi T, Aizawa T, Watanabe S, Tsugawa K, Kawaguchi S, Seya K, Matsumiya T, Tanaka H

Renal failure   43 ( 1 )   643 - 650   2021年12月

Hepatic Macrophages Express Melanoma Differentiation-Associated Gene 5 in Nonalcoholic Steatohepatitis.

Kawaguchi S, Sakuraba H, Horiuchi M, Ding J, Matsumiya T, Seya K, Iino C, Endo T, Kikuchi H, Yoshida S, Hiraga H, Fukuda S, Imaizumi T

Inflammation   45 ( 1 )   343 - 355   2021年09月

Expression of IFN-induced transmembrane protein 1 in glomerular endothelial cells.

Hashimoto S, Imaizumi T, Watanabe S, Aizawa T, Tsugawa K, Kawaguchi S, Seya K, Matsumiya T, Tanaka H

Pediatrics international : official journal of the Japan Pediatric Society   63 ( 9 )   1075 - 1081   2021年09月

Daily Brazilian green propolis intake elevates blood artepillin C levels in humans.

Ding J, Matsumiya T, Hayakari R, Shiba Y, Kawaguchi S, Seya K, Ueno K, Imaizumi T

Journal of the science of food and agriculture   101 ( 11 )   4855 - 4861   2021年08月

Porphyromonas gingivalis lipopolysaccharide induces interleukin-6 and c-c motif chemokine ligand 2 expression in cultured hCMEC/D3 human brain microvascular endothelial cells.

Sato N, Matsumoto T, Kawaguchi S, Seya K, Matsumiya T, Ding J, Aizawa T, Imaizumi T

Gerodontology   39 ( 2 )   139 - 147   2021年02月

Daily Brazilian green propolis intake elevates blood artepillin C levels in humans.

Jiangli Ding, Tomoh Matsumiya, Ryo Hayakari, Yuko Shiba, Shogo Kawaguchi, Kazuhiko Seya, Kayo Ueno, Tadaatsu Imaizumi

Journal of the science of food and agriculture   2021年02月

Human aortic valve interstitial cells obtained from patients with aortic valve stenosis are vascular endothelial growth factor receptor 2 positive and contribute to ectopic calcification.

Liu X, Yu Z, Daitoku K, Fukuda I, Motomura S, Matsumiya T, Imaizumi T, Furukawa KI, Seya K

Journal of pharmacological sciences   145 ( 2 )   213 - 221   2021年02月

Role of MDA5 in regulating CXCL10 expression induced by TLR3 signaling in human rheumatoid fibroblast-like synoviocytes.

Tatsuro Saruga, Tadaatsu Imaizumi, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Eiji Sasaki, Norihiro Sasaki, Ryoko Uesato, Yasuyuki Ishibashi

Molecular biology reports   2021年01月

Tryptanthrin suppresses double-stranded RNA-induced CXCL10 expression via inhibiting the phosphorylation of STAT1 in human umbilical vein endothelial cells.

Shogo Kawaguchi, Hirotake Sakuraba, Hidezumi Kikuchi, Noriyuki Numao, Taka Asari, Hiroto Hiraga, Jiangli Ding, Tomoh Matsumiya, Kazuhiko Seya, Shinsaku Fukuda, Tadaatsu Imaizumi

Molecular immunology   129   32 - 38   2021年01月

Tryptanthrin suppresses double-stranded RNA-induced CXCL10 expression via inhibiting the phosphorylation of STAT1 in human umbilical vein endothelial cells.

Kawaguchi S, Sakuraba H, Kikuchi H, Numao N, Asari T, Hiraga H, Ding J, Matsumiya T, Seya K, Fukuda S, Imaizumi T

Molecular immunology   129   32 - 38   2021年01月

IFIT Proteins Are Involved in CXCL10 Expression in Human Glomerular Endothelial Cells Treated with a Toll-Like Receptor 3 Agonist.

Imaizumi T, Hashimoto S, Sato R, Umetsu H, Aizawa T, Watanabe S, Kawaguchi S, Matsumiya T, Seya K, Ding J, Tanaka H

Kidney & blood pressure research   46 ( 1 )   74 - 83   2021年

Interleukin-6 via Toll-Like Receptor 3 Signaling Attenuates the Expression of Proinflammatory Chemokines in Human Podocytes.

Umetsu H, Watanabe S, Imaizumi T, Aizawa T, Tsugawa K, Kawaguchi S, Seya K, Matsumiya T, Tanaka H

Kidney & blood pressure research   46 ( 2 )   207 - 218   2021年

Expression of IFN-induced Transmembrane Protein 1 in Glomerular Endothelial Cells.

Shun Hashimoto, Tadaatsu Imaizumi, Shojiro Watanabe, Tomomi Aizawa, Koji Tsugawa, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Hiroshi Tanaka

Pediatrics international : official journal of the Japan Pediatric Society   2020年12月

IFIT Proteins Are Involved in CXCL10 Expression in Human Glomerular Endothelial Cells Treated with a Toll-Like Receptor 3 Agonist.

Tadaatsu Imaizumi, Shun Hashimoto, Riko Sato, Hidenori Umetsu, Tomomi Aizawa, Shojiro Watanabe, Shogo Kawaguchi, Tomoh Matsumiya, Kazuhiko Seya, Jiangli Ding, Hiroshi Tanaka

Kidney & blood pressure research   1 - 12   2020年12月

Endothelial expression of fractalkine (CX3CL1) is induced by Toll-like receptor 3 signaling in cultured human glomerular endothelial cells

Koji Hirono, Tadaatsu Imaizumi, Tomomi Aizawa, Shojiro Watanabe, Koji Tsugawa, Toshihiro Shiratori, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Etsuro Ito, Hiroshi Tanaka

Modern Rheumatology   30 ( 6 )   1074 - 1081   2020年11月

Toll-Like Receptor 3 as a Recurrence Risk Factor and a Potential Molecular Therapeutic Target in Colorectal Cancer.

Tatsuya Yoshida, Takuya Miura, Tomoh Matsumiya, Hidemi Yoshida, Hajime Morohashi, Yoshiyuki Sakamoto, Akira Kurose, Tadaatsu Imaizumi, Kenichi Hakamada

Clinical and experimental gastroenterology   13   427 - 438   2020年10月

ISG56 is involved in CXCL10 expression induced by TLR3 signaling in BEAS-2B bronchial epithelial cells.

Shiratori T, Imaizumi T, Hirono K, Kawaguchi S, Matsumiya T, Seya K, Tasaka S

Experimental lung research   46 ( 6 )   1 - 8   2020年05月

Polyinosinic-Polycytidylic Acid Induces CXCL1 Expression in Cultured hCMEC/D3 Human Cerebral Microvascular Endothelial Cells.

Li Y, Imaizumi T, Matsumiya T, Seya K, Kawaguchi S, Ding J, Ohkuma H

Neuroimmunomodulation   27 ( 1 )   1 - 10   2020年04月

Polyinosinic-Polycytidylic Acid Induces CXCL1 Expression in Cultured hCMEC/D3 Human Cerebral Microvascular Endothelial Cells.

Yuchen Li, Tadaatsu Imaizumi, Tomoh Matsumiya, Kazuhiko Seya, Shogo Kawaguchi, Jiangli Ding, Hiroki Ohkuma

Neuroimmunomodulation   27 ( 1 )   38 - 47   2020年04月

Interferon-induced transmembrane protein 1 and Myxovirus resistance protein 1 are induced by polyinosinic-polycytidylic acid in cultured hCMEC/D3 human cerebral microvascular endothelial cells.

Tadaatsu Imaizumi, Urara Satake, Ruri Miyashita, Shogo Kawaguchi, Tomoh Matsumiya, Kazuhiko Seya, Jiangli Ding, Hiroshi Tanaka

Journal of neuroimmunology   337   577047 - 577047   2019年12月

Interferon-induced transmembrane protein 1 and Myxovirus resistance protein 1 are induced by polyinosinic-polycytidylic acid in cultured hCMEC/D3 human cerebral microvascular endothelial cells.

Imaizumi T, Satake U, Miyashita R, Kawaguchi S, Matsumiya T, Seya K, Ding J, Tanaka H

Journal of neuroimmunology   337   577047 - 577047   2019年12月

Melanoma Differentiation-Associated Gene 5 Positively Modulates TNF-α-Induced CXCL10 Expression in Cultured HuH-7 and HLE Cells.

Shogo Kawaguchi, Hirotake Sakuraba, Toshihiro Haga, Tomoh Matsumiya, Kazuhiko Seya, Tetsu Endo, Naoya Sawada, Chikara Iino, Hidezumi Kikuchi, Hiroto Hiraga, Shinsaku Fukuda, Tadaatsu Imaizumi

Inflammation   42 ( 6 )   2095 - 2104   2019年12月

Melanoma Differentiation-Associated Gene 5 Positively Modulates TNF-α-Induced CXCL10 Expression in Cultured HuH-7 and HLE Cells.

Kawaguchi S, Sakuraba H, Haga T, Matsumiya T, Seya K, Endo T, Sawada N, Iino C, Kikuchi H, Hiraga H, Fukuda S, Imaizumi T

Inflammation   42 ( 6 )   2095 - 2104   2019年12月

Endothelial expression of fractalkine (CX3CL1) is induced by Toll-like receptor 3 signaling in cultured human glomerular endothelial cells.

Koji Hirono, Tadaatsu Imaizumi, Tomomi Aizawa, Shojiro Watanabe, Koji Tsugawa, Toshihiro Shiratori, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Etsuro Ito, Hiroshi Tanaka

Modern rheumatology   1 - 8   2019年11月

〈一般演題抄録〉一本鎖RNA ウイルスのゲノムRNA 分解機構解明へ向けた基礎検討

木村 紗也佳, 松宮 朋穂, 吉田 秀見, 瀬谷 和彦, 川口 章吾, 今泉 忠淳

弘前医学   69 ( 1-4 )   207   2019年03月

〈一般演題抄録〉胆道閉鎖症におけるウイルス感染の関与に関する分子生物学的検討

木村 俊郎, 今泉 忠淳, 吉田 秀見, 松宮 朋穂, 瀬谷 和彦, 川口 章吾, 早狩 亮, 島田 拓, 吉田 達哉, 小林 完, 平林 健, 袴田 健一

弘前医学   69 ( 1-4 )   201   2019年03月

Cytosolic Sensors of Viral RNA Are Involved in the Production of Interleukin-6 via Toll-Like Receptor 3 Signaling in Human Glomerular Endothelial Cells.

Qiang Liu, Tadaatsu Imaizumi, Tomomi Aizawa, Koji Hirono, Shogo Kawaguchi, Shojiro Watanabe, Koji Tsugawa, Tomoh Matsumiya, Kazuhiko Seya, Hidemi Yoshida, Hiroshi Tanaka

Kidney & blood pressure research   44 ( 1 )   62 - 71   2019年02月

Cytosolic Sensors of Viral RNA Are Involved in the Production of Interleukin-6 via Toll-Like Receptor 3 Signaling in Human Glomerular Endothelial Cells.

Liu Q, Imaizumi T, Aizawa T, Hirono K, Kawaguchi S, Watanabe S, Tsugawa K, Matsumiya T, Seya K, Yoshida H, Tanaka H

Kidney & blood pressure research   44 ( 1 )   62 - 71   2019年

Role of the ISR-ATF4 pathway and its cross talk with Nrf2 in mitochondrial quality control

Shuya Kasai, Hiromi Yamazaki, Kunikazu Tanji, Máté János Engler, Tomoh Matsumiya, Ken Itoh

Journal of Clinical Biochemistry and Nutrition   64 ( 1 )   1 - 12   2019年

Effect of low-concentration amyloid-β 1–42 (Aβ42) on human neuroblastoma SH-SY5Y cell viability: neuroprotective potential of combination use with carnosic acid, rebamipide, edaravone, and resveratrol

Yoshida Hidemi, Hashimoto Yuko, Fukushima Takashi, Tanji Kunikazu, Matsumiya Tomoh, Seya Kazuhiko, Kawaguchi Shogo, Imaizumi Tadaatsu

Hirosaki Medical Journal   70 ( 1 )   24 - 38   2019年

〈一般抄録演題〉パーキンソン病患者の末梢血単核球におけるオートファジーの変化

三木 康生, 下山 修司, 早狩 亮, 今 智矢, 上野達哉 達哉, 丹治 邦和, 松宮 朋穂, 対馬 栄輝, 森 文秋, 冨山 誠彦, 若林 孝一

弘前医学   69 ( 1-4 )   201   2019年

Interferon-stimulated gene 60 (ISG60) constitutes a negative feedback loop in the downstream of TLR3 signaling in hCMEC/D3 cells.

Tadaatsu Imaizumi, Naoko Sassa, Shogo Kawaguchi, Tomoh Matsumiya, Hidemi Yoshida, Kazuhiko Seya, Toshihiro Shiratori, Koji Hirono, Hiroshi Tanaka

Journal of neuroimmunology   324   16 - 21   2018年11月

Interferon-stimulated gene 60 (ISG60) constitutes a negative feedback loop in the downstream of TLR3 signaling in hCMEC/D3 cells.

Imaizumi T, Sassa N, Kawaguchi S, Matsumiya T, Yoshida H, Seya K, Shiratori T, Hirono K, Tanaka H

Journal of neuroimmunology   324   16 - 21   2018年11月

<b>Gnetin C suppresses double-stranded RNA-induced C-C motif chemokine ligand 2 (CCL2) and CCL5 production by inhibiting Toll-like receptor 3 signaling </b><b>pathway </b>

Hidemi YOSHIDA, Tadaatsu IMAIZUMI, Tomoh MATSUMIYA, Kazuhiko SEYA, Shogo KAWAGUCHI, Hiroshi TANAKA

Biomedical Research   39 ( 5 )   231 - 240   2018年10月

The Essential Role of Double-Stranded RNA-Dependent Antiviral Signaling in the Degradation of Nonself Single-Stranded RNA in Nonimmune Cells.

Sayaka Kimura, Tomoh Matsumiya, Yuko Shiba, Michi Nakanishi, Ryo Hayakari, Shogo Kawaguchi, Hidemi Yoshida, Tadaatsu Imaizumi

Journal of immunology (Baltimore, Md. : 1950)   201 ( 3 )   1044 - 1052   2018年08月

The Essential Role of Double-Stranded RNA-Dependent Antiviral Signaling in the Degradation of Nonself Single-Stranded RNA in Nonimmune Cells.

Kimura S, Matsumiya T, Shiba Y, Nakanishi M, Hayakari R, Kawaguchi S, Yoshida H, Imaizumi T

Journal of immunology (Baltimore, Md. : 1950)   201 ( 3 )   1044 - 1052   2018年08月

<b>Gnetin C, a resveratrol dimer, reduces amyloid-β 1–42 (Aβ42) production and ameliorates Aβ42-lowered cell viability in cultured SH-SY5Y human neuroblastoma </b><b>cells </b>

Syota SEINO, Takeru KIMOTO, Hidemi YOSHIDA, Kunikazu TANJI, Tomoh MATSUMIYA, Ryo HAYAKARI, Kazuhiko SEYA, Shogo KAWAGUCHI, Kazushi TSURUGA, Hiroshi TANAKA, Tadaatsu IMAIZUMI

Biomedical Research   39 ( 3 )   105 - 115   2018年06月

Retinoic acid-inducible gene-I, melanoma differentiation-associated gene 5 and C-X-C motif chemokine ligand 10 are induced by a Toll-like receptor 3 agonist in human brain microvascular endothelial cells

Tadaatsu Imaizumi, Akine Arai, Shogo Kawaguchi, Ryo Hayakari, Tomoh Matsumiya, Kazuhiko Seya, Hidemi Yoshida, Hiroshi Tanaka

Clinical and Experimental Neuroimmunology   9 ( 3 )   189 - 197   2018年05月

Alteration of autophagy-related proteins in peripheral blood mononuclear cells of patients with Parkinson's disease.

Yasuo Miki, Shuji Shimoyama, Tomoya Kon, Tatsuya Ueno, Ryo Hayakari, Kunikazu Tanji, Tomoh Matsumiya, Eiki Tsushima, Fumiaki Mori, Koichi Wakabayashi, Masahiko Tomiyama

Neurobiology of aging   63   33 - 43   2018年03月

Alteration of autophagy-related proteins in peripheral blood mononuclear cells of patients with Parkinson's disease.

Miki Y, Shimoyama S, Kon T, Ueno T, Hayakari R, Tanji K, Matsumiya T, Tsushima E, Mori F, Wakabayashi K, Tomiyama M

Neurobiology of aging   63   33 - 43   2018年03月

Toll-Like Receptor 3 Signaling Contributes to Regional Neutrophil Recruitment in Cultured Human Glomerular Endothelial Cells.

Qiang Liu, Tadaatsu Imaizumi, Shogo Kawaguchi, Tomomi Aizawa, Tomoh Matsumiya, Shojiro Watanabe, Koji Tsugawa, Hidemi Yoshida, Kazushi Tsuruga, Kensuke Joh, Hiroshi Kijima, Hiroshi Tanaka

Nephron   139 ( 4 )   349 - 358   2018年

Gnetin C, a resveratrol dimer, reduces amyloid-β 1-42 (Aβ42) production and ameliorates Aβ42-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells.

Syota Seino, Takeru Kimoto, Hidemi Yoshida, Kunikazu Tanji, Tomoh Matsumiya, Ryo Hayakari, Kazuhiko Seya, Shogo Kawaguchi, Kazushi Tsuruga, Hiroshi Tanaka, Tadaatsu Imaizumi

Biomedical research (Tokyo, Japan)   39 ( 3 )   105 - 115   2018年

Gnetin C suppresses double-stranded RNA-induced C-C motif chemokine ligand 2 (CCL2) and CCL5 production by inhibiting Toll-like receptor 3 signaling pathway.

Hidemi Yoshida, Tadaatsu Imaizumi, Tomoh Matsumiya, Kazuhiko Seya, Shogo Kawaguchi, Hiroshi Tanaka

Biomedical research (Tokyo, Japan)   39 ( 5 )   231 - 240   2018年

Toll-Like Receptor 3 Signaling Contributes to Regional Neutrophil Recruitment in Cultured Human Glomerular Endothelial Cells.

Liu Q, Imaizumi T, Kawaguchi S, Aizawa T, Matsumiya T, Watanabe S, Tsugawa K, Yoshida H, Tsuruga K, Joh K, Kijima H, Tanaka H

Nephron   139 ( 4 )   349 - 358   2018年

Rebamipide reduces amyloid-β 1-42 (Aβ42) production and ameliorates Aβ43-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells.

Kenta Fukui, Kazuma Yachi, Hidemi Yoshida, Kunikazu Tanji, Tomoh Matsumiya, Ryo Hayakari, Kazushi Tsuruga, Hiroshi Tanaka, Tadaatsu Imaizumi

Neuroscience research   124   40 - 50   2017年11月

Rebamipide reduces amyloid-β 1-42 (Aβ42) production and ameliorates Aβ43-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells.

Fukui K, Yachi K, Yoshida H, Tanji K, Matsumiya T, Hayakari R, Tsuruga K, Tanaka H, Imaizumi T

Neuroscience research   124   40 - 50   2017年11月

Expression of CCL5 is induced by polyinosinic : polycytidylic acid in cultured hCMEC/D3 human brain microvascular endothelial cells

Akine Arai, Hidemi Yoshida, Ryo Hayakari, Tomoh Matsumiya, Shogo Kawaguchi, Kazuhiko Seya, Hiroshi Tanaka, Tadaatsu Imaizumi

Clinical and Experimental Neuroimmunology   8 ( 4 )   331 - 340   2017年09月

Interferon (IFN)-induced protein 35 (IFI35) negatively regulates IFN-β-phosphorylated STAT1-RIG-I-CXCL10/CCL5 axis in U373MG astrocytoma cells treated with polyinosinic-polycytidylic acid.

Kyogo Shirai, Taku Shimada, Hidemi Yoshida, Ryo Hayakari, Tomoh Matsumiya, Kunikazu Tanji, Manabu Murakami, Hiroshi Tanaka, Tadaatsu Imaizumi

Brain research   1658   60 - 67   2017年03月

Interferon (IFN)-induced protein 35 (IFI35) negatively regulates IFN-β-phosphorylated STAT1-RIG-I-CXCL10/CCL5 axis in U373MG astrocytoma cells treated with polyinosinic-polycytidylic acid.

Shirai K, Shimada T, Yoshida H, Hayakari R, Matsumiya T, Tanji K, Murakami M, Tanaka H, Imaizumi T

Brain research   1658   60 - 67   2017年03月

Chloroquine attenuates TLR3/IFN-β signaling in cultured normal human mesangial cells: A possible protective effect against renal damage in lupus nephritis

Tadaatsu Imaizumi, Ryo Hayakari, Tomoh Matsumiya, Hidemi Yoshida, Kazushi Tsuruga, Shojiro Watanabe, Shogo Kawaguchi, Hiroshi Tanaka

Modern Rheumatology   27 ( 6 )   1004 - 1009   2017年02月

Chloroquine attenuates TLR3/IFN-β signaling in cultured normal human mesangial cells: A possible protective effect against renal damage in lupus nephritis.

Tadaatsu Imaizumi, Ryo Hayakari, Tomoh Matsumiya, Hidemi Yoshida, Kazushi Tsuruga, Shojiro Watanabe, Shogo Kawaguchi, Hiroshi Tanaka

Modern rheumatology   1 - 18   2017年02月

Cylindromatosis (CYLD), a Deubiquitinase, Attenuates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells.

Tadaatsu Imaizumi, Ryo Hayakari, Shojiro Watanabe, Tomomi Aizawa, Tomoh Matsumiya, Hidemi Yoshida, Kazushi Tsuruga, Shogo Kawaguchi, Hiroshi Tanaka

Kidney & blood pressure research   42 ( 5 )   942 - 950   2017年

CCL5 is induced by TLR 3 signaling in HuCCT1 human biliary epithelial cells: possible involvement in the pathogenesis of biliary atresia.

Taku Shimada, Tadaatsu Imaizumi, Kyogo Shirai, Tetsuya Tatsuta, Toshiro Kimura, Ryo Hayakari, Hidemi Yoshida, Tomoh Matsumiya, Hiroshi Kijima, Hiroki Mizukami, Kenichi Hakamada

Biomedical research (Tokyo, Japan)   38 ( 5 )   269 - 276   2017年

CCL5 is induced by TLR 3 signaling in HuCCT1 human biliary epithelial cells: possible involvement in the pathogenesis of biliary atresia.

Shimada T, Imaizumi T, Shirai K, Tatsuta T, Kimura T, Hayakari R, Yoshida H, Matsumiya T, Kijima H, Mizukami H, Hakamada K

Biomedical research (Tokyo, Japan)   38 ( 5 )   269 - 276   2017年

〈一般演題抄録〉鉄キレーターdesferrioxamineは培養アス トロサイト細胞株におけるCXCL8発現を誘導する

恩田 郁, 吉田 秀見, 松宮 朋穂, 早狩 亮, 今泉 忠淳

弘前医学   67 ( 2-4 )   185   2017年

〈一般演題抄録〉ウィルス感染と胆道閉鎖症－CCL5 の意義－

島田 拓, 木村 俊郎, 早狩 亮, 松宮 朋穂, 吉田 秀見, 今泉 忠淳, 袴田 健一

弘前医学   68 ( 1 )   89   2017年

Cylindromatosis (CYLD), a Deubiquitinase, Attenuates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells.

Imaizumi T, Hayakari R, Watanabe S, Aizawa T, Matsumiya T, Yoshida H, Tsuruga K, Kawaguchi S, Tanaka H

Kidney & blood pressure research   42 ( 5 )   942 - 950   2017年

Non-Canonical Role of IKKα in the Regulation of STAT1 Phosphorylation in Antiviral Signaling.

Fei Xing, Tomoh Matsumiya, Yuko Shiba, Ryo Hayakari, Hidemi Yoshida, Tadaatsu Imaizumi

PloS one   11 ( 12 )   e0168696 - e0168696   2016年12月

Critical Role of IRF-3 in the Direct Regulation of dsRNA-Induced Retinoic Acid-Inducible Gene-I (RIG-I) Expression.

Ryo Hayakari, Tomoh Matsumiya, Fei Xing, Hidemi Yoshida, Makoto Hayakari, Tadaatsu Imaizumi

PloS one   11 ( 9 )   e0163520 - e0163520   2016年09月

Interferon (IFN)-Induced Protein 35 (IFI35), a Type I Interferon-Dependent Transcript, Upregulates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells.

Tadaatsu Imaizumi, Chikashi Yano, Akiko Numata, Koji Tsugawa, Ryo Hayakari, Tomoh Matsumiya, Hidemi Yoshida, Shojiro Watanabe, Kazushi Tsuruga, Shogo Kawaguchi, Manabu Murakami, Hiroshi Tanaka

Kidney & blood pressure research   41 ( 5 )   635 - 642   2016年09月

Critical Role of IRF-3 in the Direct Regulation of dsRNA-Induced Retinoic Acid-Inducible Gene-I (RIG-I) Expression.

Hayakari R, Matsumiya T, Xing F, Yoshida H, Hayakari M, Imaizumi T

PloS one   11 ( 9 )   e0163520   2016年09月

Interferon-stimulated gene (ISG) 60, as well as ISG56 and ISG54, positively regulates TLR3/IFN-β/STAT1 axis in U373MG human astrocytoma cells.

Imaizumi T, Yoshida H, Hayakari R, Xing F, Wang L, Matsumiya T, Tanji K, Kawaguchi S, Murakami M, Tanaka H

Neuroscience research   105   35 - 41   2016年04月

Clock Gene Expressions are Altered by Co-culture of Gingival Fibroblasts and Oral Cancer Cells

Ken Furudate, Tomoh Matsumiya, Kosei Kubota, Hirotaka Sakaki, Yoshihiro Tamura, Hiroshi Kijima, Tadaatsu Imaizumi, Hiroto Kimura, Wataru Kobayashi.

Hirosaki Medical Journal   66 ( 2-4 )   135 - 142   2016年03月

Desferrioxamine, An Iron Chelator, Induces CXCL8 Expression in U373MG Human Astrocytoma Cells

Onda K, Yoshida H, Hayakari R, Xing F, Lian W, Matsumiya T, Kawaguchi S, Murakami M, Imaizumi T

Hirosaki Medical Journal   2016年03月

Alteration of Antiviral Signalling by Single Nucleotide Polymorphisms (SNPs) of Mitochondrial Antiviral Signalling Protein (MAVS).

Fei Xing, Tomoh Matsumiya, Ryo Hayakari, Hidemi Yoshida, Shogo Kawaguchi, Ippei Takahashi, Shigeyuki Nakaji, Tadaatsu Imaizumi

PloS one   11 ( 3 )   e0151173 - e0151173   2016年03月

Interferon-Stimulated Gene 15, a Type I Interferon-Dependent Transcript, Is Involved in a Negative Feedback Loop in Innate Immune Reactions in Human Mesangial Cells.

Tadaatsu Imaizumi, Taku Shimada, Tomoh Matsumiya, Hidemi Yoshida, Shojiro Watanabe, Kazushi Tsuruga, Shogo Kawaguchi, Manabu Murakami, Kensuke Joh, Hiroshi Tanaka

Nephron   132 ( 2 )   144 - 152   2016年02月

Alteration of Antiviral Signalling by Single Nucleotide Polymorphisms (SNPs) of Mitochondrial Antiviral Signalling Protein (MAVS).

Xing F, Matsumiya T, Hayakari R, Yoshida H, Kawaguchi S, Takahashi I, Nakaji S, Imaizumi T

PloS one   11 ( 3 )   e0151173   2016年

〈一般演題抄録〉下気道におけるレチノイン酸誘導遺伝子-Ⅰ様受容体を介した抗ウイルス自然免疫応答

千葉 友揮, 松宮 朋穂, 佐藤 次生, 早狩 亮, 邢 飛, 吉田 秀見, 丹治 邦和, 水上 浩哉, 今泉 忠淳, 伊藤 悦朗

弘前医学   67 ( 1 )   112   2016年

Non-Canonical Role of IKKα in the Regulation of STAT1 Phosphorylation in Antiviral Signaling.

Xing F, Matsumiya T, Shiba Y, Hayakari R, Yoshida H, Imaizumi T

PloS one   11 ( 12 )   e0168696   2016年

Interferon-Stimulated Gene 15, a Type I Interferon-Dependent Transcript, Is Involved in a Negative Feedback Loop in Innate Immune Reactions in Human Mesangial Cells.

Imaizumi T, Shimada T, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Kawaguchi S, Murakami M, Joh K, Tanaka H

Nephron   132 ( 2 )   144 - 52   2016年

Interferon (IFN)-Induced Protein 35 (IFI35), a Type I Interferon-Dependent Transcript, Upregulates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells.

Imaizumi T, Yano C, Numata A, Tsugawa K, Hayakari R, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Kawaguchi S, Murakami M, Tanaka H

Kidney & blood pressure research   41 ( 5 )   635 - 642   2016年

Interferon (IFN)-Induced Protein 35 (IFI35), a Type I Interferon-Dependent Transcript, Upregulates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells.

Tadaatsu Imaizumi, Chikashi Yano, Akiko Numata, Koji Tsugawa, Ryo Hayakari, Tomoh Matsumiya, Hidemi Yoshida, Shojiro Watanabe, Kazushi Tsuruga, Shogo Kawaguchi, Manabu Murakami, Hiroshi Tanaka

Kidney & blood pressure research   41 ( 5 )   635 - 642   2016年

Desferrioxamine, an iron chelator, induces CXCL8 expression in U373MG human astrocytoma cells

Onda Kaoru, Yoshida Hidemi, Hayakari Ryo, Xing Fei, Wang Lian, Matsumiya Tomoh, Kawaguchi Shogo, Murakami Manabu, Imaizumi Tadaatsu

Hirosaki Medical Journal   66 ( 2-4 )   127 - 134   2016年

Clock gene expressions are altered by co-culture of gingival fibroblasts and oral cancer cells

Furudate Ken, Matsumiya Tomoh, Hayakari Ryo, Xing Fei, Kubota Kosei, Sakaki Hirotaka, Tamura Yoshihiro, Kijima Hiroshi, Imaizumi Tadaatsu, Kimura Hiroto, Kobayashi Wataru

Hirosaki Medical Journal   66 ( 2-4 )   135 - 142   2016年

Retinoic acid-inducible gene-I-like receptor (RLR)-mediated antiviral innate immune responses in the lower respiratory tract: Roles of TRAF3 and TRAF5.

Yuki Chiba, Tomoh Matsumiya, Tsugumi Satoh, Ryo Hayakari, Ken Furudate, Fei Xing, Hidemi Yoshida, Kunikazu Tanji, Hiroki Mizukami, Tadaatsu Imaizumi, Etsuro Ito

Biochemical and biophysical research communications   467 ( 2 )   191 - 196   2015年11月

Retinoic acid-inducible gene-I-like receptor (RLR)-mediated antiviral innate immune responses in the lower respiratory tract: Roles of TRAF3 and TRAF5.

Chiba Y, Matsumiya T, Satoh T, Hayakari R, Furudate K, Xing F, Yoshida H, Tanji K, Mizukami H, Imaizumi T, Ito E

Biochemical and biophysical research communications   467 ( 2 )   191 - 6   2015年11月

Identification of a point mutation in the SH3BP2 gene in cherubism

Hirotaka Sakaki, Tomoh Matsumiya, Ken Furudate, Wataru Kobayashi, Takao Kon, Ryohei Itoh, Hiroto Kimura

Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology   27 ( 6 )   880 - 883   2015年11月

Identification of a point mutation in the SH3BP2 gene in cherubism

Sakaki H, Matsumiya T, Furudate K, Kobayashi Y, Kon T, Itoh R, and Kimura H

Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology   27 ( 6 )   880 - 883   2015年11月

Toll-like receptor 3 signaling contributes to the expression of a neutrophil chemoattractant, CXCL1 in human mesangial cells.

Tadaatsu Imaizumi, Tomomi Aizawa, Chihiro Segawa, Michiko Shimada, Kazushi Tsuruga, Shogo Kawaguchi, Tomoh Matsumiya, Hidemi Yoshida, Kensuke Joh, Hiroshi Tanaka

Clinical and experimental nephrology   2015年10月

Trehalose intake induces chaperone molecules along with autophagy in a mouse model of Lewy body disease.

Kunikazu Tanji, Yasuo Miki, Atsushi Maruyama, Junsei Mimura, Tomoh Matsumiya, Fumiaki Mori, Tadaatsu Imaizumi, Ken Itoh, Koichi Wakabayashi

Biochemical and biophysical research communications   465 ( 4 )   746 - 752   2015年10月

Trehalose intake induces chaperone molecules along with autophagy in a mouse model of Lewy body disease.

Tanji K, Miki Y, Maruyama A, Mimura J, Matsumiya T, Mori F, Imaizumi T, Itoh K, Wakabayashi K

Biochemical and biophysical research communications   465 ( 4 )   746 - 52   2015年10月

Molecular mechanism of clock genes in tumor microenvironment

K. Furudate, T Matsumiiya, K Kubota, H Sakaki, T Kon, W Kobayashi, H Kimura

International Journal of Oral and Maxillofacial Surgery   2015年10月

Toll-like receptor 3 signaling contributes to the expression of a neutrophil chemoattractant, CXCL1 in human mesangial cells.

Imaizumi T, Aizawa T, Segawa C, Shimada M, Tsuruga K, Kawaguchi S, Matsumiya T, Yoshida H, Joh K, Tanaka H

Clinical and experimental nephrology   19 ( 5 )   761 - 70   2015年10月

Interferon-stimulated gene (ISG) 60, as well as ISG56 and ISG54, positively regulates TLR3/IFN-β/STAT1 axis in U373MG human astrocytoma cells.

Tadaatsu Imaizumi, Hidemi Yoshida, Ryo Hayakari, Fei Xing, Lian Wang, Tomoh Matsumiya, Kunikazu Tanji, Shogo Kawaguchi, Manabu Murakami, Hiroshi Tanaka

Neuroscience research   2015年09月

Desferrioxamine, an iron chelator, inhibits CXCL10 expression induced by polyinosinic-polycytidylic acid in U373MG human astrocytoma cells.

Tadaatsu Imaizumi, Nina Sakashita, Yasuaki Mushiga, Hidemi Yoshida, Ryo Hayakari, Fei Xing, Liang Wang, Tomoh Matsumiya, Kunikazu Tanji, Yuki Chiba, Ken Furudate, Shogo Kawaguchi, Manabu Murakami, Hiroshi Tanaka

Neuroscience research   94   10 - 16   2015年05月

Carnosic acid attenuates apoptosis induced by amyloid-β 1-42 or 1-43 in SH-SY5Y human neuroblastoma cells.

Pengfei Meng, Hidemi Yoshida, Kunikazu Tanji, Tomoh Matsumiya, Fei Xing, Ryo Hayakari, Liang Wang, Kazushi Tsuruga, Hiroshi Tanaka, Junsei Mimura, Kunio Kosaka, Ken Itoh, Ippei Takahashi, Shogo Kawaguchi, Tadaatsu Imaizumi

Neuroscience research   94   1 - 9   2015年05月

Carnosic acid attenuates apoptosis induced by amyloid-β 1-42 or 1-43 in SH-SY5Y human neuroblastoma cells.

Meng P, Yoshida H, Tanji K, Matsumiya T, Xing F, Hayakari R, Wang L, Tsuruga K, Tanaka H, Mimura J, Kosaka K, Itoh K, Takahashi I, Kawaguchi S, Imaizumi T

Neuroscience research   94   1 - 9   2015年05月

Desferrioxamine, an iron chelator, inhibits CXCL10 expression induced by polyinosinic-polycytidylic acid in U373MG human astrocytoma cells.

Imaizumi T, Sakashita N, Mushiga Y, Yoshida H, Hayakari R, Xing F, Wang L, Matsumiya T, Tanji K, Chiba Y, Furudate K, Kawaguchi S, Murakami M, Tanaka H

Neuroscience research   94   10 - 6   2015年05月

Tumor necrosis factor-α synergistically enhances polyinosinic-polycytidylic acid-induced toll-like receptor 3 signaling in cultured normal human mesangial cells: possible involvement in the pathogenesis of lupus nephritis.

Tadaatsu Imaizumi, Tomomi Aizawa, Ryo Hayakari, Fei Xing, Pengfei Meng, Kazushi Tsuruga, Tomoh Matsumiya, Hidemi Yoshida, Liang Wang, Tetsuya Tatsuta, Hiroshi Tanaka

Clinical and experimental nephrology   2015年02月

Tumor necrosis factor-α synergistically enhances polyinosinic-polycytidylic acid-induced toll-like receptor 3 signaling in cultured normal human mesangial cells: possible involvement in the pathogenesis of lupus nephritis.

Imaizumi T, Aizawa T, Hayakari R, Xing F, Meng P, Tsuruga K, Matsumiya T, Yoshida H, Wang L, Tatsuta T, Tanaka H

Clinical and experimental nephrology   19 ( 1 )   75 - 81   2015年02月

Emerging functional cross-talk between the Keap1-Nrf2 system and mitochondria.

Itoh K, Ye P, Matsumiya T, Tanji K, Ozaki T

Ｊｏｕｒｎａｌ　ｏｆ　Ｃｌｉｎｉｃａｌ　Ｂｉｏｃｈｅｍｉｓｔｒｙ　ａｎｄ　Ｎｕｔｒｉｔｉｏｎ   56 ( 2 )   91 - 97   2015年

ISG54 and ISG56 are induced by TLR3 signaling in U373MG human astrocytoma cells: Possible involvement in CXCL10 expression.

Tadaatsu Imaizumi, Akiko Numata, Chikashi Yano, Hidemi Yoshida, Pengfei Meng, Ryo Hayakari, Fei Xing, Lian Wang, Tomoh Matsumiya, Kunikazu Tanji, Tetsuya Tatsuta, Manabu Murakami, Hiroshi Tanaka

Neuroscience research   2014年07月

ISG54 and ISG56 are induced by TLR3 signaling in U373MG human astrocytoma cells: possible involvement in CXCL10 expression.

Imaizumi T, Numata A, Yano C, Yoshida H, Meng P, Hayakari R, Xing F, Wang L, Matsumiya T, Tanji K, Tatsuta T, Murakami M, Tanaka H

Neuroscience research   84   34 - 42   2014年07月

Phosphorylation of serine 349 of p62 in Alzheimer's disease brain.

Tanji K, Miki Y, Ozaki T, Maruyama A, Yoshida H, Mimura J, Matsumiya T, Mori F, Imaizumi T, Itoh K, Kakita A, Takahashi H, Wakabayashi K

Acta neuropathologica communications   2   50 - 50   2014年05月

Phosphorylation of serine 349 of p62 in Alzheimer's disease brain.

Kunikazu Tanji, Yasuo Miki, Taku Ozaki, Atsushi Maruyama, Hidemi Yoshida, Junsei Mimura, Tomoh Matsumiya, Fumiaki Mori, Tadaatsu Imaizumi, Ken Itoh, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi

Acta neuropathologica communications   2   50 - 50   2014年05月

Carnosic acid suppresses the production of amyloid-β 1-42 and 1-43 by inducing an α-secretase TACE/ADAM17 in U373MG human astrocytoma cells.

Hidemi Yoshida, Pengfei Meng, Tomoh Matsumiya, Kunikazu Tanji, Ryo Hayakari, Fei Xing, Liang Wang, Kazushi Tsuruga, Hiroshi Tanaka, Junsei Mimura, Kunio Kosaka, Ken Itoh, Ippei Takahashi, Tadaatsu Imaizumi

Neuroscience research   79   83 - 93   2014年02月

Role of type I- and type II-interferon in expression of melanoma differentiation-associated gene-5 in HSC-3 oral squamous carcinoma cells.

Tomoh Matsumiya, Ryo Hayakari, Norihiko Narita, Ryohei Ito, Takao Kon, Kosei Kubota, Hirotaka Sakaki, Hidemi Yoshida, Tadaatsu Imaizumi, Wataru Kobayashi, Hiroto Kimura

Biomedical research (Tokyo, Japan)   35 ( 1 )   9 - 16   2014年02月

Periosteum-derived cells respond to mechanical stretch and activate Wnt and BMP signaling pathways.

Ryohei Ito, Tomoh Matsumiya, Takao Kon, Norihiko Narita, Kosei Kubota, Hirotaka Sakaki, Taku Ozaki, Tadaatsu Imaizumi, Wataru Kobayashi, Hiroto Kimura

Biomedical research (Tokyo, Japan)   35 ( 1 )   69 - 79   2014年02月

Carnosic acid suppresses the production of amyloid-β 1-42 and 1-43 by inducing an α-secretase TACE/ADAM17 in U373MG human astrocytoma cells.

Yoshida H, Meng P, Matsumiya T, Tanji K, Hayakari R, Xing F, Wang L, Tsuruga K, Tanaka H, Mimura J, Kosaka K, Itoh K, Takahashi I, Imaizumi T

Neuroscience research   79   83 - 93   2014年02月

Mizoribine selectively attenuates monocyte chemoattractant protein-1 production in cultured human glomerular mesangial cell: a possible benefit of its use in the treatment of lupus nephritis.

Tomomi Aizawa, Tadaatsu Imaizumi, Kazushi Tsuruga, Shojiro Watanabe, Yuki Chiba, Tomoh Matsumiya, Hidemi Yoshida, Hiroshi Tanaka

Nephrology (Carlton, Vic.)   19 ( 1 )   47 - 52   2014年01月

Periosteum-derived cells respond to mechanical stretch and activate Wnt and BMP signaling pathways.

Ito R, Matsumiya T, Kon T, Narita N, Kubota K, Sakaki H, Ozaki T, Imaizumi T, Kobayashi W, Kimura H

Biomedical research (Tokyo, Japan)   35 ( 1 )   69 - 79   2014年

培養ヒト口腔扁平上皮癌細胞におけるTNF-α 依存的なGRO-α の誘導： GRO-α による血管新生作用と腫瘍増殖作用について

成田 紀彦, 松宮 朋穂, 今 敬生, 早狩 亮, 伊藤 良平, 久保田 耕世, 榊 宏剛, 古舘 健, 吉田 秀見, 今泉 忠淳, 小林 恒, 木村 博人

弘前医学   65 ( 2-4 )   147 - 155   2014年

Role of type I- and type II-interferon in expression of melanoma differentiation-associated gene-5 in HSC-3 oral squamous carcinoma cells.

Matsumiya T, Hayakari R, Narita N, Ito R, Kon T, Kubota K, Sakaki H, Yoshida H, Imaizumi T, Kobayashi W, Kimura H

Biomedical research (Tokyo, Japan)   35 ( 1 )   9 - 16   2014年

Mizoribine selectively attenuates monocyte chemoattractant protein-1 production in cultured human glomerular mesangial cell: A possible benefit of its use in the treatment of lupus nephritis

Tomomi Aizawa, Tadaatsu Imaizumi, Kazushi Tsuruga, Shojiro Watanabe, Yuki Chiba, Tomoh Matsumiya, Hidemi Yoshida, Hiroshi Tanaka

Nephrology   19 ( 1 )   47 - 52   2013年12月

Glomerular expression of myxovirus resistance protein 1 in human mesangial cells: possible activation of innate immunity in the pathogenesis of lupus nephritis.

Shojiro Watanabe, Tadaatsu Imaizumi, Kazushi Tsuruga, Tomomi Aizawa, Tatsuya Ito, Tomoh Matsumiya, Hidemi Yoshida, Kensuke Joh, Etsuro Ito, Hiroshi Tanaka

Nephrology (Carlton, Vic.)   18 ( 12 )   833 - 837   2013年12月

Glomerular expression of myxovirus resistance protein 1 in human mesangial cells: Possible activation of innate immunity in the pathogenesis of lupus nephritis

Shojiro Watanabe, Tadaatsu Imaizumi, Kazushi Tsuruga, Tomomi Aizawa, Tatsuya Ito, Tomoh Matsumiya, Hidemi Yoshida, Kensuke Joh, Etsuro Ito, Hiroshi Tanaka

Nephrology   18 ( 12 )   833 - 837   2013年11月

TLR4 signaling induces retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5 in mesangial cells.

Tadaatsu Imaizumi, Tomomi Aizawa-Yashiro, Shojiro Watanabe, Tomoh Matsumiya, Hidemi Yoshida, Tetsuya Tatsuta, Fei Xing, Pengfei Meng, Ryo Hayakari, Kazushi Tsuruga, Hiroshi Tanaka

Journal of nephrology   26 ( 5 )   886 - 893   2013年09月

TLR4 signaling induces retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5 in mesangial cells.

Imaizumi T, Aizawa-Yashiro T, Watanabe S, Matsumiya T, Yoshida H, Tatsuta T, Xing F, Meng P, Hayakari R, Tsuruga K, Tanaka H

Journal of nephrology   26 ( 5 )   886 - 893   2013年09月

Novel role for molecular transporter importin 9 in posttranscriptional regulation of IFN-ε expression.

Tomoh Matsumiya, Fei Xing, Masayuki Ebina, Ryo Hayakari, Tadaatsu Imaizumi, Hidemi Yoshida, Hideaki Kikuchi, Matthew K Topham, Kei Satoh, Diana M Stafforini

Journal of immunology (Baltimore, Md. : 1950)   191 ( 4 )   1907 - 1915   2013年08月

Novel role for molecular transporter importin 9 in posttranscriptional regulation of IFN-ε expression.

Matsumiya T, Xing F, Ebina M, Hayakari R, Imaizumi T, Yoshida H, Kikuchi H, Topham MK, Satoh K, Stafforini DM

Journal of immunology (Baltimore, Md. : 1950)   191 ( 4 )   1907 - 15   2013年08月

MDA5 and ISG56 mediate CXCL10 expression induced by toll-like receptor 4 activation in U373MG human astrocytoma cells.

Tadaatsu Imaizumi, Keishu Murakami, Kasumi Ohta, Hirotaka Seki, Tomoh Matsumiya, Pengfei Meng, Ryo Hayakari, Fei Xing, Tomomi Aizawa-Yashiro, Tetsuya Tatsuta, Hidemi Yoshida, Hiroshi Kijima

Neuroscience research   76 ( 4 )   195 - 206   2013年08月

MDA5 and ISG56 mediate CXCL10 expression induced by toll-like receptor 4 activation in U373MG human astrocytoma cells.

Imaizumi T, Murakami K, Ohta K, Seki H, Matsumiya T, Meng P, Hayakari R, Xing F, Aizawa-Yashiro T, Tatsuta T, Yoshida H, Kijima H

Neuroscience research   76 ( 4 )   195 - 206   2013年08月

How are STAT1 and cholesterol metabolism associated in antiviral responses?

Matsumiya T, Imaizumi T

JAK-STAT   2 ( 3 )   e24189   2013年07月

Interaction between interferon-stimulated gene 56 and melanoma differentiation-associated gene 5 in Toll-like receptor 3 signaling in normal human mesangial cells.

Tadaatsu Imaizumi, Tomomi Aizawa-Yashiro, Tomoh Matsumiya, Hidemi Yoshida, Shojiro Watanabe, Kazushi Tsuruga, Tetsuya Tatsuta, Fei Xing, Ryo Hayakari, Pengfei Meng, Hiroshi Tanaka

American journal of nephrology   37 ( 2 )   118 - 125   2013年06月

Effects of Brazilian green propolis on double-stranded RNA-mediated induction of interferon-inducible gene and inhibition of recruitment of polymorphonuclear cells.

Ryo Hayakari, Tomoh Matsumiya, Fei Xing, Janeth C Tayone, Junichi Dempoya, Tetsuya Tatsuta, Tomomi Aizawa-Yashiro, Tadaatsu Imaizumi, Hidemi Yoshida, Kei Satoh

Journal of the science of food and agriculture   93 ( 3 )   646 - 651   2013年02月

Carnosic acid suppresses the production of amyloid-β 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells.

Pengfei Meng, Hidemi Yoshida, Tomoh Matsumiya, Tadaatsu Imaizumi, Kunikazu Tanji, Fei Xing, Ryo Hayakari, Junichi Dempoya, Tetsuya Tatsuta, Tomomi Aizawa-Yashiro, Junsei Mimura, Kunio Kosaka, Ken Itoh, Kei Satoh

Neuroscience research   75 ( 2 )   94 - 102   2013年02月

Glomerular expression of fractalkine is induced by polyinosinic-polycytidylic acid in human mesangial cells: possible involvement of fractalkine after viral infection.

Tomomi Aizawa-Yashiro, Tadaatsu Imaizumi, Kazushi Tsuruga, Shojiro Watanabe, Tomoh Matsumiya, Ryo Hayakari, Hidemi Yoshida, Kei Satoh, Etsuro Ito, Hiroshi Tanaka

Pediatric research   73 ( 2 )   180 - 186   2013年02月

Carnosic acid suppresses the production of amyloid-β 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells.

Meng P, Yoshida H, Matsumiya T, Imaizumi T, Tanji K, Xing F, Hayakari R, Dempoya J, Tatsuta T, Aizawa-Yashiro T, Mimura J, Kosaka K, Itoh K, Satoh K

Neuroscience research   75 ( 2 )   94 - 102   2013年02月

Glomerular expression of fractalkine is induced by polyinosinic-polycytidylic acid in human mesangial cells: possible involvement of fractalkine after viral infection.

Aizawa-Yashiro T, Imaizumi T, Tsuruga K, Watanabe S, Matsumiya T, Hayakari R, Yoshida H, Satoh K, Ito E, Tanaka H

Pediatric research   73 ( 2 )   180 - 6   2013年02月

Interaction between interferon-stimulated gene 56 and melanoma differentiation-associated gene 5 in Toll-like receptor 3 signaling in normal human mesangial cells.

Imaizumi T, Aizawa-Yashiro T, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Tatsuta T, Xing F, Hayakari R, Meng P, Tanaka H

American journal of nephrology   37 ( 2 )   118 - 25   2013年

Double-stranded RNA induces biphasic STAT1 phosphorylation by both type I interferon (IFN)-dependent and type I IFN-independent pathways.

Junichi Dempoya, Tomoh Matsumiya, Tadaatsu Imaizumi, Ryo Hayakari, Fei Xing, Hidemi Yoshida, Ken Okumura, Kei Satoh

Journal of virology   86 ( 23 )   12760 - 12769   2012年12月

Double-stranded RNA induces biphasic STAT1 phosphorylation by both type I interferon (IFN)-dependent and type I IFN-independent pathways.

Dempoya J, Matsumiya T, Imaizumi T, Hayakari R, Xing F, Yoshida H, Okumura K, Satoh K

Journal of virology   86 ( 23 )   12760 - 9   2012年12月

Effects of Brazilian green propolis on double-stranded RNA-mediated induction of interferon-inducible gene and inhibition of recruitment of polymorphonuclear cells

Ryo Hayakari, Tomoh Matsumiya, Fei Xing, Janeth C Tayone, Junichi Dempoya, Tetsuya Tatsuta, Tomomi Aizawa-Yashiro, Tadaatsu Imaizumi, Hidemi Yoshida, Kei Satoh

Journal of the Science of Food and Agriculture   93 ( 3 )   646 - 651   2012年09月

Expression of melanoma differentiation associated gene 5 is increased in human gastric mucosa infected with Helicobacter pylori.

Tetsuya Tatsuta, Tadaatsu Imaizumi, Tadashi Shimoyama, Manabu Sawaya, Tanji Kunikazu, Tomoh Matsumiya, Hidemi Yoshida, Kei Satoh, Shinsaku Fukuda

Journal of clinical pathology   65 ( 9 )   839 - 843   2012年09月

Foreign RNA induces the degradation of mitochondrial antiviral signaling protein (MAVS): the role of intracellular antiviral factors.

Fei Xing, Tomoh Matsumiya, Koji Onomoto, Ryo Hayakari, Tadaatsu Imaizumi, Hidemi Yoshida, Mitsutoshi Yoneyama, Takashi Fujita, Kei Satoh

PloS one   7 ( 9 )   e45136 - e45136   2012年09月

Melanoma differentiation-associated gene 5 regulates the expression of a chemokine CXCL10 in human mesangial cells: implications for chronic inflammatory renal diseases.

Tadaatsu Imaizumi, Tomomi Aizawa-Yashiro, Kazushi Tsuruga, Hiroshi Tanaka, Tomoh Matsumiya, Hidemi Yoshida, Tetsuya Tatsuta, Fei Xing, Ryo Hayakari, Kei Satoh

The Tohoku journal of experimental medicine   228 ( 1 )   17 - 26   2012年09月

Expression of melanoma differentiation associated gene 5 is increased in human gastric mucosa infected with Helicobacter pylori.

Tatsuta T, Imaizumi T, Shimoyama T, Sawaya M, Kunikazu T, Matsumiya T, Yoshida H, Satoh K, Fukuda S

Journal of clinical pathology   65 ( 9 )   839 - 43   2012年09月

Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity.

Koji Onomoto, Michihiko Jogi, Ji-Seung Yoo, Ryo Narita, Shiho Morimoto, Azumi Takemura, Suryaprakash Sambhara, Atushi Kawaguchi, Suguru Osari, Kyosuke Nagata, Tomoh Matsumiya, Hideo Namiki, Mitsutoshi Yoneyama, Takashi Fujita

PloS one   7 ( 8 )   e43031 - e43031   2012年08月

Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity.

Onomoto K, Jogi M, Yoo JS, Narita R, Morimoto S, Takemura A, Sambhara S, Kawaguchi A, Osari S, Nagata K, Matsumiya T, Namiki H, Yoneyama M, Fujita T

PloS one   7 ( 8 )   e43031   2012年

Melanoma differentiation-associated gene 5 regulates the expression of a chemokine CXCL10 in human mesangial cells: implications for chronic inflammatory renal diseases.

Imaizumi T, Aizawa-Yashiro T, Tsuruga K, Tanaka H, Matsumiya T, Yoshida H, Tatsuta T, Xing F, Hayakari R, Satoh K

The Tohoku journal of experimental medicine   228 ( 1 )   17 - 26   2012年

Foreign RNA induces the degradation of mitochondrial antiviral signaling protein (MAVS): the role of intracellular antiviral factors.

Xing F, Matsumiya T, Onomoto K, Hayakari R, Imaizumi T, Yoshida H, Yoneyama M, Fujita T, Satoh K

PloS one   7 ( 9 )   e45136   2012年

Basic-helix-loop-helix transcription factor DEC2 constitutes negative feedback loop in IFN-β-mediated inflammatory responses in human mesangial cells.

Imaizumi T, Sato F, Tanaka H, Matsumiya T, Yoshida H, Yashiro-Aizawa T, Tsuruga K, Hayakari R, Kijima H, Satoh K

Immunology Letters   2011年12月

Polyinosinic-polycytidylic acid induces the expression of interferon-stimulated gene 20 in mesangial cells.

Imaizumi T, Tanaka H, Mechti N, Matsumiya T, Yoshida H, Sato F, Aizawa-Yashiro T, Tsuruga K, Hayakari R, Satoh K.

Nephron. Experimental nephrology   2011年08月

Polyinosinic-polycytidylic acid induces the expression of interferon-stimulated gene 20 in mesangial cells.

Tadaatsu Imaizumi, Hiroshi Tanaka, Nadir Mechti, Tomoh Matsumiya, Hidemi Yoshida, Fuyuki Sato, Tomomi Aizawa-Yashiro, Kazushi Tsuruga, Ryo Hayakari, Kei Satoh

Nephron. Experimental nephrology   119 ( 2 )   e40 - e48   2011年08月

Basic-helix-loop-helix transcription factor DEC2 constitutes negative feedback loop in IFN-β-mediated inflammatory responses in human mesangial cells.

Imaizumi T, Sato F, Tanaka H, Matsumiya T, Yoshida H, Yashiro-Aizawa T, Tsuruga K, Hayakari R, Kijima H, Satoh K

Immunology letters   136 ( 1 )   37 - 43   2011年04月

Edaravone and carnosic acid synergistically enhance the expression of nerve growth factor in human astrocytes under hypoxia/reoxygenation.

Hidemi Yoshida, Junsei Mimura, Tadaatsu Imaizumi, Tomoh Matsumiya, Akira Ishikawa, Norifumi Metoki, Kunikazu Tanji, Ken Ota, Ryo Hayakari, Kunio Kosaka, Ken Itoh, Kei Satoh

Neuroscience research   69 ( 4 )   291 - 298   2011年04月

Edaravone and carnosic acid synergistically enhance the expression of nerve growth factor in human astrocytes under hypoxia/reoxygenation.

Yoshida H, Mimura J, Imaizumi T, Matsumiya T, Ishikawa A, Metoki N, Tanji K, Ota K, Hayakari R, Kosaka K, Itoh K, Satoh K

Neuroscience research   69 ( 4 )   291 - 8   2011年04月

Antiviral signaling through retinoic acid-inducible gene-I-like receptors.

Tomoh Matsumiya, Tadaatsu Imaizumi, Hidemi Yoshida, Kei Satoh

Archivum immunologiae et therapiae experimentalis   59 ( 1 )   41 - 48   2011年02月

Antiviral signaling through retinoic acid-inducible gene-I-like receptors.

Matsumiya T, Imaizumi T, Yoshida H, Satoh K

Archivum immunologiae et therapiae experimentalis   59 ( 1 )   41 - 8   2011年02月

Edaravone and carnosic acid synergistically enhance the expression of nerve growth factor in human astrocytes under hypoxia/reoxygenation.

Yoshida H, Mimura J, Imaizumi T, Matsumiya T, Ishikawa A, Metoki N, Tanji K, Ota K, Hayakari R, Kosaka K, Itoh K, Satoh K.

Neuroscience Research   2011年01月

Polyinosinic-Polycytidylic Acid Induces the Expression of Interferon-Stimulated Gene 20 in Mesangial Cells

Tadaatsu Imaizumi, Hiroshi Tanaka, Nadir Mechti, Tomoh Matsumiya, Hidemi Yoshida, Fuyuki Sato, Tomomi Aizawa-Yashiro, Kazushi Tsuruga, Ryo Hayakari, Kei Satoh

NEPHRON EXPERIMENTAL NEPHROLOGY   119 ( 2 )   E40 - E48   2011年

Polyinosinic-polycytidylic acid induces the expression of interferon-stimulated gene 20 in mesangial cells.

Imaizumi T, Tanaka H, Mechti N, Matsumiya T, Yoshida H, Sato F, Aizawa-Yashiro T, Tsuruga K, Hayakari R, Satoh K

Nephron. Experimental nephrology   119 ( 2 )   e40 - 8   2011年

Polyinosinic-polycytidylic acid induces the expression of interferon-stimulated gene 20 in mesangial cells.

Tadaatsu Imaizumi, Hiroshi Tanaka, Nadir Mechti, Tomoh Matsumiya, Hidemi Yoshida, Fuyuki Sato, Tomomi Aizawa-Yashiro, Kazushi Tsuruga, Ryo Hayakari, Kei Satoh

Nephron. Experimental nephrology   119 ( 2 )   e40-8 - 8   2011年

Edaravone improves the expression of nerve growth factor in human astrocytes subjected to hypoxia/reoxygenation.

Yoshida H, Metoki N, Ishikawa A, Imaizumi T, Matsumiya T, Tanji K, Ota K, Ohyama C, Satoh K

Neuroscience Research   2010年11月

Retinoic acid-inducible gene-I is induced by double-stranded RNA and regulates the expression of CC chemokine ligand (CCL) 5 in human mesangial cells.

Tadaatsu Imaizumi, Hiroshi Tanaka, Tomoh Matsumiya, Hidemi Yoshida, Kunikazu Tanji, Kazushi Tsuruga, Eishin Oki, Tomomi Aizawa-Yashiro, Etsuro Ito, Kei Satoh

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association   25 ( 11 )   3534 - 3539   2010年11月

Retinoic acid-inducible gene-I is induced by double-stranded RNA and regulates the expression of CC chemokine ligand (CCL) 5 in human mesangial cells.

Imaizumi T, Tanaka H, Matsumiya T, Yoshida H, Tanji K, Tsuruga K, Oki E, Aizawa-Yashiro T, Ito E, Satoh K

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association   25 ( 11 )   3534 - 9   2010年11月

IFN-γ and TNF-α synergistically induce microRNA-155 which regulates TAB2/IP-10 expression in human mesangial cells.

Imaizumi T, Tanaka H, Tajima A, Yokono Y, Matsumiya T, Yoshida H, Tsuruga K, Aizawa-Yashiro T, Hayakari R, Inoue I, Ito E, Satoh K.

American journal of nephrology.   2010年10月

Function and regulation of retinoic acid-inducible gene-I.

Tomoh Matsumiya, Diana M Stafforini

Critical reviews in immunology   30 ( 6 )   489 - 513   2010年10月

IFN-γ and TNF-α synergistically induce microRNA-155 which regulates TAB2/IP-10 expression in human mesangial cells.

Tadaatsu Imaizumi, Hiroshi Tanaka, Atsushi Tajima, Yoshikazu Yokono, Tomoh Matsumiya, Hidemi Yoshida, Kazushi Tsuruga, Tomomi Aizawa-Yashiro, Ryo Hayakari, Ituro Inoue, Etsuro Ito, Kei Satoh

American journal of nephrology   32 ( 5 )   462 - 468   2010年08月

Retinoic acid-inducible gene-I (RIG-I) is induced by IFN-γ in human mesangial cells in culture: Possible involvement of RIG-I in the inflammation in lupus nephritis.

Imaizumi T, Tanaka H, Tajima A, Tsuruga K, Oki E, Sashinami H, Matsumiya T, Yoshida H, Inoue I, Ito E

Lupus   19 ( 7 )   830 - 836   2010年06月

Retinoic acid-inducible gene-I is induced by double-stranded RNA and regulates the expression of CC chemokine ligand (CCL) 5 in human mesangial cells.

Imaizumi T, Tanaka H, Matsumiya T, Yoshida H, Tanji K, Tsuruga K, Oki E, Aizawa-Yashiro T, Ito E, Satoh K.

Nephrology, dialysis, transplantation   2010年05月

Characterization of Synergistic Induction of CX3CL1/Fractalkine by TNF-alpha and IFN-gamma in Vascular Endothelial Cells: An Essential Role for TNF-alpha in Post-Transcriptional Regulation of CX3CL1 （共著）

Matsumiya T, Ota K, Imaizumi T, Yoshida H and Satoh K.

The Journal of Immunology   184 ( 8 )   4205 - 4214   2010年04月

Characterization of synergistic induction of CX3CL1/fractalkine by TNF-alpha and IFN-gamma in vascular endothelial cells: an essential role for TNF-alpha in post-transcriptional regulation of CX3CL1.

Matsumiya T, Ota K, Imaizumi T, Yoshida H, Kimura H, Satoh K

Journal of immunology (Baltimore, Md. : 1950)   184 ( 8 )   4205 - 14   2010年04月

今月の主題 広義のアポリポ蛋白 各論 〈臨床検査への応用の可能性〉 Lp-PLA2 (PAF acetylhydrolase)

今泉 忠淳, 吉田 秀見, 松宮 朋穂, 佐藤 敬

臨床検査   54 ( 4 )   389 - 393   2010年04月

Edaravone improves the expression of nerve growth factor in human astrocytes subjected to hypoxia/reoxygenation.

Hidemi Yoshida, Norifumi Metoki, Akira Ishikawa, Tadaatsu Imaizumi, Tomoh Matsumiya, Kunikazu Tanji, Ken Ota, Chikara Ohyama, Kei Satoh

Neuroscience research   66 ( 3 )   284 - 289   2010年03月

Interferon-alpha2b induces p21cip1/waf1 degradation and cell proliferation in HeLa cells.

Ken Ota, Tomoh Matsumiya, Hirotake Sakuraba, Tadaatsu Imaizumi, Hidemi Yoshida, Shogo Kawaguchi, Shinsaku Fukuda, Kei Satoh

Cell cycle (Georgetown, Tex.)   9 ( 1 )   131 - 139   2010年01月

Interferon-alpha2b induces p21cip1/waf1 degradation and cell proliferation in HeLa cells.

Ken Ota, Tomoh Matsumiya, Hirotake Sakuraba, Tadaatsu Imaizumi, Hidemi Yoshida, Shogo Kawaguchi, Shinsaku Fukuda, Kei Satoh

Cell cycle (Georgetown, Tex.)   9 ( 1 )   131 - 9   2010年01月

Interferon-alpha2b induces p21cip1/waf1 degradation and cell proliferation in HeLa cells.

Ota K, Matsumiya T, Sakuraba H, Imaizumi T, Yoshida H, Kawaguchi S, Fukuda S, Satoh K

Cell cycle (Georgetown, Tex.)   9 ( 1 )   131 - 9   2010年01月

Function and regulation of retinoic acid-inducible gene-I.

Tomoh Matsumiya, Diana M Stafforini

Critical reviews in immunology   30 ( 6 )   489 - 513   2010年

IFN-γ and TNF-α synergistically induce microRNA-155 which regulates TAB2/IP-10 expression in human mesangial cells.

Imaizumi T, Tanaka H, Tajima A, Yokono Y, Matsumiya T, Yoshida H, Tsuruga K, Aizawa-Yashiro T, Hayakari R, Inoue I, Ito E, Satoh K

American journal of nephrology   32 ( 5 )   462 - 8   2010年

Function and regulation of retinoic acid-inducible gene-I.

Matsumiya T, Stafforini DM

Critical reviews in immunology   30 ( 6 )   489 - 513   2010年

Retinoic acid-inducible gene-I is constitutively expressed and involved in IFN-gamma-stimulated CXCL9-11 production in intestinal epithelial cells.

Kawaguchi S, Ishiguro Y, Imaizumi T, Mori F, Matsumiya T, Yoshida H, Ota K, Sakuraba H, Yamagata K, Sato Y, Tanji K, Haga T, Wakabayashi K, Fukuda S, Satoh K

Immunology letters   123 ( 1 )   9 - 13   2009年03月

The levels of retinoic acid-inducible gene I are regulated by heat shock protein 90-alpha.

Matsumiya T, Imaizumi T, Yoshida H, Satoh K, Topham MK, Stafforini DM

Journal of immunology (Baltimore, Md. : 1950)   182 ( 5 )   2717 - 25   2009年03月

Tumor-necrosis factor-alpha induces retinoic acid-inducible gene-I in rheumatoid fibroblast-like synoviocytes.

Imaizumi T, Matsumiya T, Yoshida H, Naraoka T, Uesato R, Ishibashi Y, Ota K, Toh S, Fukuda S, Satoh K

Immunology letters   122 ( 1 )   89 - 93   2009年01月

Retinoic acid-inducible gene-I is induced by interferon-gamma and regulates CXCL11 expression in HeLa cells.

Yuzawa E, Imaizumi T, Matsumiya T, Yoshida H, Fukuhara R, Kimura H, Fukui A, Tanji K, Mori F, Wakabayashi K, Fujii S, Mizunuma H, Satoh K

Life sciences   82 ( 11-12 )   670 - 5   2008年03月

Retinoic acid-inducible gene-I is induced by interferon-gamma and regulates CXCL11 expression in HeLa cells (共著）

Yuzawa E, et al.

Life sciences   82 ( 11-12 )   670 - 675   2008年01月

IFN-epsilon mediates TNF-alpha-induced STAT1 phosphorylation and induction of retinoic acid-inducible gene-I in human cervical cancer cells.

Tomoh Matsumiya, Stephen M Prescott, Diana M Stafforini

Journal of immunology (Baltimore, Md. : 1950)   179 ( 7 )   4542 - 9   2007年10月

IFN-epsilon mediates TNF-alpha-induced STAT1 phosphorylation and induction of retinoic acid-inducible gene-I in human cervical cancer cells.

Matsumiya T, Prescott SM, Stafforini DM

Journal of immunology (Baltimore, Md. : 1950)   179 ( 7 )   4542 - 9   2007年10月

Expression of vascular endothelial growth factor by photodynamic therapy with mono-L-aspartyl chlorin e6 (NPe6) in oral squamous cell carcinoma.

Nakagawa H, Matsumiya T, Sakaki H, Imaizumi T, Kubota K, Kusumi A, Kobayashi W, Kimura H

Oral oncology   43 ( 6 )   544 - 50   2007年07月

Photodynamic therapy with mono-L-aspartyl chlorin e6 can cause necrosis of squamous cell carcinoma of tongue: experimental study on an animal model of nude mouse.

Kobayashi W, Liu Q, Nakagawa H, Sakaki H, Teh B, Matsumiya T, Yoshida H, Imaizumi T, Satoh K, Kimura H

Oral oncology   42 ( 1 )   46 - 50   2006年01月

Listeria monocytogenes induces the expression of retinoic acid-inducible gene-I.

Imaizumi T, Sashinami H, Mori F, Matsumiya T, Yoshida H, Nakane A, Wakabayashi K, Oyama C, Satoh K

Microbiology and immunology   50 ( 10 )   811 - 5   2006年

Photodynamic therapy upregulates expression of Mac-1 and generation of leukotriene B(4) by human polymorphonuclear leukocytes.

Kobayashi W, Liu Q, Matsumiya T, Nakagawa H, Yoshida H, Imaizumi T, Satoh K, Kimura H

Oral oncology   40 ( 5 )   506 - 10   2004年05月

Effect of MG132, a proteasome inhibitor, on the expression of growth related oncogene protein-alpha in human umbilical vein endothelial cells.

Shibata T, Imaizumi T, Matsumiya T, Tamo W, Hatakeyama M, Yoshida H, Munakata H, Fukuda I, Satoh K

Cytokine   24 ( 3 )   67 - 73   2003年11月

15-Deoxy-D12,14-prostaglandin J2 inhibits CX3CL1/fractalkine expression in human endothelial cells.

Imaizumi T, Matsumiya T, Tamo W, Shibata T, Fujimoto K, Kumagai M, Yoshida H, Cui XF, Tanji K, Hatakeyama M, Wakabayashi K, Satoh K

Immunology and cell biology   80 ( 6 )   531 - 6   2002年12月

Interferon-gamma stimulates the expression of galectin-9 in cultured human endothelial cells.

Tadaatsu Imaizumi, Mika Kumagai, Naoko Sasaki, Hidekachi Kurotaki, Fumiaki Mori, Masako Seki, Nozomu Nishi, Koji Fujimoto, Kunikazu Tanji, Takeo Shibata, Wakako Tamo, Tomoh Matsumiya, Hidemi Yoshida, Xue-Fan Cui, Shingo Takanashi, Katsumi Hanada, Ken Okumura, Soroku Yagihashi, Koichi Wakabayashi, Takanori Nakamura, Mitsuomi Hirashima, Kei Satoh

Journal of leukocyte biology   72 ( 3 )   486 - 91   2002年09月

Interferon-gamma stimulates the expression of galectin-9 in cultured human endothelial cells.

Imaizumi T, Kumagai M, Sasaki N, Kurotaki H, Mori F, Seki M, Nishi N, Fujimoto K, Tanji K, Shibata T, Tamo W, Matsumiya T, Yoshida H, Cui XF, Takanashi S, Hanada K, Okumura K, Yagihashi S, Wakabayashi K, Nakamura T, Hirashima M, Satoh K

Journal of leukocyte biology   72 ( 3 )   486 - 91   2002年09月

Platelet-activating factor enhances the expression of vascular endothelial growth factor in normal human astrocytes.

Yoshida H, Imaizumi T, Tanji K, Matsumiya T, Sakaki H, Kimura D, Cui XF, Kumagai M, Tamo W, Shibata T, Hatakeyama M, Sato Y, Satoh K

Brain research   944 ( 1-2 )   65 - 72   2002年07月

Proteasome inhibitor MG-132 enhances the expression of interleukin-6 in human umbilical vein endothelial cells: Involvement of MAP/ERK kinase.

Shibata T, Imaizumi T, Tamo W, Matsumiya T, Kumagai M, Cui XF, Yoshida H, Takaya S, Fukuda I, Satoh K

Immunology and cell biology   80 ( 3 )   226 - 30   2002年06月

Production of growth related oncogene protein-alpha in human umbilical vein endothelial cells stimulated with soluble interleukin-6 receptor-alpha: role of signal transducers, janus kinase 2 and mitogen-activated kinase kinase.

Matsumiya T, Imaizumi T, Itaya H, Shibata T, Yoshida H, Sakaki H, Kimura H, Satoh K

Life sciences   70 ( 26 )   3179 - 90   2002年05月

Retinoic acid-inducible gene-I is induced in endothelial cells by LPS and regulates expression of COX-2.

Imaizumi T, Aratani S, Nakajima T, Carlson M, Matsumiya T, Tanji K, Ookawa K, Yoshida H, Tsuchida S, McIntyre TM, Prescott SM, Zimmerman GA, Satoh K

Biochemical and biophysical research communications   292 ( 1 )   274 - 9   2002年03月

Desferrioxamine, an iron chelator, upregulates cyclooxygenase-2 expression and prostaglandin production in a human macrophage cell line

K Tanji, T Imaizumi, T Matsumiya, H Itaya, K Fujimoto, CF Cui, T Toki, E Ito, H Yoshida, K Wakabayashi, K Satoh

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS   1530 ( 2-3 )   227 - 235   2001年02月

Cisplatin inhibits the expression of X-chromosome-linked inhibitor of apoptosis protein in an oral carcinoma cell line

T. Matsumiya, T. Imaizumi, H. Yoshida, H. Kimura, K. Satoh

Oral Oncology   37 ( 3 )   296 - 300   2001年

遊離空腸移植による口腔再建術の臨床的検討

小林 恒, 小林 慎, 廣田 和香, 福井 朗, 佐藤 寿, 八木橋 靖子, 遠藤 有美, 松宮 朋穂, 木村 博人

日本口腔外科学会雑誌   47 ( 12 )   778 - 786   2001年

Interferon-γ Stimulates the Expression of CX3CL1/Fractalkine in Cultured Human Endothelial Cells

IMAIZUMI TADAATSU, MATSUMIYA TOMOH, FUJIMOTO KOJI, OKAMOTO KAORI, CUI XUEFAN, OHTAKI USHIO, YOSHIDA HIDEMI, SATOH KEI

THE TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE   192 ( 2 )   127 - 139   2000年

口腔へん平上皮癌における組織学的悪性度の検討　　予後および術後頚部リンパ節転移について

中野 靖子, 小林 恒, 虻川 東嗣, 遠藤 有美, 松宮 朋穂, 木村 博人

日本口腔腫瘍学会誌   9 ( 3 )   93 - 100   1997年

培養ヒト脳微小血管内皮細胞におけるinterferon-stimulated gene 60(ISG60)の発現に対するToll様受容体3アゴニストの影響

今泉 忠淳, 松宮 朋穂, 吉田 秀見

日本生化学会大会プログラム・講演要旨集   91回   [2P - 341]   2018年9月

Lp-PLA2の遺伝子多型と疾患

吉田秀見，今泉忠淳，松宮朋穂，瀬谷和彦

臨床化学   47 ( 2 )   122 - 127   2018年4月

【Lp-PLA2研究の進歩】Lp-PLA2の遺伝子多型と疾患

吉田 秀見, 今泉 忠淳, 松宮 朋穂, 瀬谷 和彦

臨床化学   47 ( 2 )   122 - 127   2018年4月

培養ヒト脳微小血管内皮細胞におけるToll様受容体3とケモカイン発現

荒井 玲音, 島田 拓, 松宮 朋穂, 吉田 秀見, 早狩 亮, 川口 章吾, 瀬谷 和彦, 今泉 忠淳

弘前医学   68 ( 2-4 )   188 - 188   2018年3月

Toll様受容体3のアゴニストは培養ヒト脳微小血管内皮細胞におけるCCL5発現を誘導する

今泉 忠淳, 松宮 朋穂, 吉田 秀見

生命科学系学会合同年次大会   2017年度   [2P - 1199]   2017年12月

ウイルス感染と胆道閉鎖症 CCL5の意義

島田 拓, 木村 俊郎, 早狩 亮, 松宮 朋穂, 吉田 秀見, 今泉 忠淳, 袴田 健一

弘前医学   68 ( 1 )   89 - 89   2017年10月

Involvement of IKK alpha in STATI phosphorylation in antiviral signaling

Tomoh Matsumiya, Fei Xing, Yuko Shiba, Ryo Hayakari, Hidemi Yoshida, Tadaatsu Imaizumi

JOURNAL OF IMMUNOLOGY   198 ( 1 )   2017年5月

脳卒中回復期患者の口腔衛生評価法確立に向けた基礎検討

清水 瞳, 小堀 文美子, 松山 哲子, 工藤 瑞葵, 木村 ゆか子, 五十嵐 緑, 久保田 耕世, 木村 典子, 松宮 朋穂, 小林 恒

日本口腔ケア学会雑誌   11 ( 3 )   202 - 202   2017年4月

鉄キレーターdesferrioxamineは培養アストロサイト細胞株におけるCXCL8発現を誘導する

恩田 郁, 吉田 秀見, 松宮 朋穂, 早狩 亮, 今泉 忠淳

弘前医学   67 ( 2-4 )   185 - 185   2017年2月

Trehalose administration inhibits inflammatory responses in the brain of Lewy body disease model mice

K. Tanji, A. Maruyama, T. Matsumiya, Y. Miki, J. Mimura, F. Mori, K. Itoh, K. Wakabayashi

EUROPEAN JOURNAL OF IMMUNOLOGY   46   164 - 164   2016年8月

パーキンソン病におけるオートファジー関連因子に関する研究

冨山 誠彦, 今 智矢, 三木 康生, 松宮 朋穂

青森県立中央病院医誌   61 ( 2 )   87 - 87   2016年6月

インターフェロン調節因子-3を介したレチノイン酸誘導遺伝子-Iの新規転写調節機構

早狩 亮, 松宮 朋穂, けい 飛, 吉田 秀見, 今泉 忠淳

弘前医学   66 ( 2-4 )   190 - 190   2016年3月

メトトレキセート関連のリンパ増殖性疾患と顎骨壊死を併発した2例

古舘健, 古舘健, 松宮朋穂, 伊藤良平, 田村好拡, 佐竹杏奈, 今敬生, 中川祥, 久保田耕世, 佐藤寿, 小林恒

日本口腔科学会学術集会プログラム・抄録集   70th   2016年

抗ウイルス因子MAVSの一塩基多型

Xing Fei, 松宮 朋穂, 早狩 亮, 吉田 秀見, 高橋 一平, 中路 重之, 今泉 忠淳

日本生化学会大会・日本分子生物学会年会合同大会講演要旨集   88回・38回   [1P0775] - [1P0775]   2015年12月

カルノシン酸はヒトアストロサイトのアミロイドβ(1-42/43)分泌を抑制する

吉田 秀見, 松宮 朋穂, 丹治 邦和, 早狩 亮, けい 飛, 三村 純正, 伊東 健, 今泉 忠淳

弘前医学   66 ( 1 )   94 - 94   2015年4月

Emerging functional cross-talk between the Keap1-Nrf2 system and mitochondria.

Itoh K, Ye P, Matsumiya T, Tanji K, Ozaki T.

Journal of clinical biochemistry and nutrition   2015年3月

Cell differentiation modulates intracellular antiviral responses in neuronal cells

Tomoh Matsumiya, Ryo Hayakari, Fei Xing, Hidemi Yoshida, Tadaatsu Imaizumi

JOURNAL OF NEUROIMMUNOLOGY   275 ( 1-2 )   89 - 89   2014年10月

Double-stranded RNA induces the expression of type I interferon-stimulated genes 54 and 56 in human astrocyte cell line

Fei Xing, Tomoh Matsumiya, Ryo Hayakari, Hidemi Yoshida, Tadaatsu Imaizumi

JOURNAL OF NEUROIMMUNOLOGY   275 ( 1-2 )   94 - 94   2014年10月

リポ蛋白関連ホスホリパーゼA2

今泉忠淳，吉田秀見，松宮朋穂

The Lipid   2013年10月

How are STAT1 and cholesterol metabolism associated in antiviral responses?

Matsumiya T, Imaizumi T

JAK-STAT   2013年6月

Type I IFN-independent RIG-I expression in response to double-stranded RNA

Ryo Hayakari, Tomoh Matsumiya, Fei Xing, Tadaatsu Imaizumi, Hidemi Yoshida

JOURNAL OF IMMUNOLOGY   190   2013年5月

【リパーゼの臨床的意義】 脂質代謝、動脈硬化における機能と臨床的意義　リポ蛋白関連 ホスホリパーゼＡ２

今泉忠淳, 吉田秀見, 松宮朋穂

The LIpids   2013年4月

Innate Immune Reactions against RNA Viruses in Renal Mesangial Cells [Innovation in Transplant and Regenerative Medicine. The 13th Meeting of Hirosaki International Forum of Medical Science. Communication Center of Hirosaki University School of Medicine. September 9, 2011, Hirosaki, Japan]

Imaizumi Tadaatsu, Aizawa Tomomi, Tanaka Hiroshi, Sato Fuyuki, Xing Fei, Matsumiya Tomoh, Yoshida Hideki, Satoh Kei

弘前醫學   64   S70 - S73   2013年

RIG-Iは口腔癌由来細胞株において細胞周期の制御に関与する

榊 宏剛, 松宮 朋穂, 久保田 耕世, 中川 祥, 小林 恒, 木村 博人

日本口腔外科学会雑誌   57 ( Suppl. )   241 - 241   2011年9月

Antiviral signaling through retinoic acid-inducible gene-I-like receptors.

Matsumiya T, Imaizumi T, Yoshida H, Satoh K.

Archivum immunologiae et therapiae experimentalis   2011年1月

Edaravoneは低酸素・再酸素化ヒトアストロサイトの神経成長因子発現を改善する

吉田 秀見, 目時 典文, 石川 玲, 今泉 忠淳, 松宮 朋穂, 丹治 邦和, 太田 健, 大山 力, 佐藤 敬

弘前医学   61 ( 2-4 )   170 - 170   2011年1月

口腔癌由来細胞株における新規遺伝子RIG-Iを用いた細胞周期制御の検討

榊 宏剛, 松宮 朋穂, 久保田 耕世, 中川 祥, 木村 博人

日本口腔外科学会雑誌   56 ( Suppl. )   255 - 255   2010年9月

Function and regulation of retinoic acid-inducible gene-I

Matsumiya T., Stafforini D.M.

Critical reviews in immunology   2010年5月

Edaravone improves the expression of nerve growth factor in human astrocytes subjected to hypoxia/reoxygenation.

Yoshida H, Metoki N, Ishikawa A, Imaizumi T, Matsumiya T, Tanji K, Ota K, Ohyama C, Satoh K

Neuroscience research   66 ( 3 )   284 - 9   2010年3月

Heat shock protein 90 protects degradation of retinoic acid-inducible gene-I

Tomoh Matsumiya, Tadaatsu Imaizumi, Hidemi Yoshida, Matthew K. Topham, Diana M. Stafforini, Kei Satoh

JOURNAL OF IMMUNOLOGY   182   2009年4月

Involvement of retinoic acid-inducible gene-I in inflammation of rheumatoid fibroblast-like synoviocytes

T. Imaizumi, T. Arikawa, T. Sato, R. Uesato, T. Matsumiya, H. Yoshida, M. Ueno, S. Yamasaki, T. Nakajima, M. Hirashima, K. Sakata, Y. Ishibashi, S. Toh, C. Ohyama, K. Satoh

CLINICAL AND EXPERIMENTAL IMMUNOLOGY   153 ( 2 )   240 - 244   2008年8月

Expression of interferon-stimulated gene 20 in vascular endothelial cells.

Imaizumi T, Mechti N, Matsumiya T, Sakaki H, Kubota K, Yoshida H, Kimura H, Satoh K

Microbiology and immunology   52 ( 1 )   30 - 5   2008年1月

Edaravone inhibits the expression of vascular endothelial growth factor in human astrocytes exposed to hypoxia.

Ishikawa A, Yoshida H, Metoki N, Toki T, Imaizumi T, Matsumiya T, Yamashita K, Taima K, Satoh K

Neuroscience research   59 ( 4 )   406 - 12   2007年12月

Retinoic acid-inducible gene-I mediates RANTES/CCL5 expression in U373MG human astrocytoma cells stimulated with double-stranded RNA.

Yoshida H, Imaizumi T, Lee SJ, Tanji K, Sakaki H, Matsumiya T, Ishikawa A, Taima K, Yuzawa E, Mori F, Wakabayashi K, Kimura H, Satoh K

Neuroscience research   58 ( 2 )   199 - 206   2007年6月

Listeria monocytogenes induces the expression of retinoic acid-inducible gene-I.

Tadaatsu Imaizumi, Hiroshi Sashinami, Fumiaki Mori, Tomoh Matsumiya, Hidemi Yoshida, Akio Nakane, Koichi Wakabayashi, Chikara Oyama, Kei Satoh

Microbiology and immunology   50 ( 10 )   811 - 5   2006年

光線力学的治療によるVEGF発現に対する検討

中川 祥, 松宮 朋穂, 榊 宏剛, 久保田 耕世, 小林 恒, 木村 博人

日本口腔外科学会雑誌   51 ( Suppl. )   169 - 169   2005年9月

Retinoic acid-inducible gene-I is induced by interleukin-β in cultured human gingival fibroblasts

Hirotaka Sakaki, T. Imaizumi, T. Matsumiya, A. Kusumi, H. Nakagawa, K. Kubota, N. Nishi, T. Nakamura, M. Hirashima, K. Satoh, H. Kimura

Oral Microbiology and Immunology   20 ( 1 )   47 - 50   2005年2月

マウス舌癌に対する光線力学療法の実験的研究

小林 恒, 中川 祥, 榊 宏剛, 久保田 耕世, 松宮 朋穂, 木村 博人

日本口腔外科学会雑誌   50 ( 13 )   895 - 895   2004年12月

nterleukin-1β induces matrix metalloproteinase-1 expression in cultured human gingival fibroblasts: role of cyclooxygenase-2 and prostaglandin E2.

共著

Oral Dis   10 ( 2 )   87 - 93   2004年3月

Mono-L-aspartyl chlorin e 6(NPe6)を用いたマウス舌癌に対する光線力学的治療に関する研究

小林 恒, 松宮 朋穂, 中川 祥, 榊 宏剛, 木村 博人

日本口腔外科学会雑誌   49 ( 13 )   826 - 827   2003年12月

Glycogen synthase kinase-3β phosphorylates synphilin-1 in vitro

TANJI Kunikazu, TOKI Tsutomu, TAMO Wakako, IMAIZUMI Tadaatsu, MATSUMIYA Tomoh, MORI Fumiaki, TAKAHASHI Hitoshi, SATOH Kei, WAKABAYASHI Koichi

Neuropathology : official journal the Japanese Society of Neuropathology   23 ( 3 )   199 - 202   2003年9月

NPe6を用いた光線力学的治療におけるc-jun/c-fos遺伝子の発現

松宮 朋穂, 小林 恒, 中川 祥, 木村 博人

日本口腔腫瘍学会誌   14 ( 4 )   124 - 124   2002年12月

Upregulation of α-synuclein by lipopolysaccharide and interleukin-1 in human macrophages

TANJI Kunikazu, MORI Fumiaki, IMAIZUMI Tadaatsu, YOSHIDA Hidemi, MATSUMIYA Tomoh, TAMO Wakako, YOSHIMOTO Makoto, ODAGIRI Hiroki, SASAKI Mutsuo, TAKAHASHI Hitoshi, SATOH Kei, WAKABAYASHI Koichi

Pathology international   52 ( 9 )   572 - 7   2002年9月

Interleukin-1 beta stimulates galectin-9 expressions in human astrocytes

H Yoshida, T Imaizumi, M Kumagai, K Kimura, C Satoh, N Hanada, K Fujimoto, N Nishi, K Tanji, T Matsumiya, F Mori, XF Cui, W Tamo, T Shibata, S Takanashi, K Okumura, T Nakamura, K Wakabayashi, M Hirashima, Y Sato, K Satoh

NEUROREPORT   12 ( 17 )   3755 - 3758   2001年12月

Soluble interleukin-6 receptor a inhibits the cytokine-induced fractalkine/CX3CL1 expression in human vascular endothelial cells in culture

T Matsumiya, T Imaizumi, K Fujimoto, XF Cui, T Shibata, W Tamo, M Kumagai, K Tanji, H Yoshida, H Kimura, K Satoh

EXPERIMENTAL CELL RESEARCH   269 ( 1 )   35 - 41   2001年9月

Synergistic stimulation, by tumor necrosis factor-alpha and interferon-gamma, of fractalkine expression in human astrocytes

H Yoshida, T Imaizumi, K Fujimoto, N Matsuo, K Kimura, XF Cui, T Matsumiya, K Tanji, T Shibata, W Tamo, M Kumagai, K Satoh

NEUROSCIENCE LETTERS   303 ( 2 )   132 - 136   2001年5月

Cisplatin inhibits the expression of X-chromosome-linked inhibitor of apoptosis protein in an oral carcinoma cell line

T Matsumiya, T Imaizumi, H Yoshida, H Kimura, K Satoh

ORAL ONCOLOGY   37 ( 3 )   296 - 300   2001年4月

Lipopolysaccharide induces the expression of cellular inhibitor of apoptosis protein-2 in human macrophages

XF Cui, T Imaizumi, H Yoshida, K Tanji, T Matsumiya, K Satoh

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS   1524 ( 2-3 )   178 - 182   2000年12月

白色海綿様母斑の3例 姉弟例

佐藤 寿, 福井 朗, 小原 はるみ, 松宮 朋穂, 木村 博人, 秋田谷 徹

日本口腔外科学会雑誌   46 ( 13 )   896 - 896   2000年12月

口腔癌手術患者におけるチタンプレート破折症例の検討

工藤 方子, 小原 はるみ, 松宮 朋穂, 佐藤 寿, 小林 恒, 木村 博人

日本口腔外科学会雑誌   46 ( 11 )   731 - 731   2000年11月

Expression of vascular endothelial growth factor in human umbilical vein endothelial cells stimulated with interleukin-1 alpha - An autocrine regulation of angiogenesis and inflammatory reactions

T Imaizumi, H Itaya, S Nasu, H Yoshida, Y Matsubara, K Fujimoto, T Matsumiya, H Kimura, D Satoh

THROMBOSIS AND HAEMOSTASIS   83 ( 6 )   949 - 955   2000年6月

Expression of tumor-necrosis factor-α(TNF-α)in cultured human endothelial cells with lipopolysacchride or interleukin-1α.

共著

Arteriosclerosis, Thrombosis, and Vascular Biology   20 ( 2 )   410 - 415   2000年2月

過去10年間に外科的矯正手術を施行した顎変形症症例の検討

福井 朗, 五十嵐 恵一, 小林 恒, 角 邦子, 松宮 朋穂, 木村 博人

弘前医学   50 ( 4 )   249 - 249   1999年3月

2023年度，臨床検査総合演習Ⅱ，専門教育科目（学部）

2023年度，臨床生理学実習，専門教育科目（学部）

2023年度，臨床生理検査学Ⅰ，専門教育科目（学部）

2023年度，臨床生理検査学Ⅱ，専門教育科目（学部）

2023年度，臨床生理検査学Ⅲ，専門教育科目（学部）

2023年度，国際保健医療学，修士課程・博士前期課程

2023年度，医学研究基礎技術実習，博士一貫課程・博士後期課程

2023年度，顎口腔腫瘍病態学演習，博士一貫課程・博士後期課程

2023年度，医学・医療の世界－感染症から身を守る－，教養教育科目

2023年度，基礎ゼミナール【M保検査】，教養教育科目

2023年度，生物学の世界－生命の起源と進化－，教養教育科目

2022年度，卒業研究（検査）〔前期〕，専門教育科目（学部）

2022年度，卒業研究（検査）〔後期〕，専門教育科目（学部）

2022年度，生理検査学総論，専門教育科目（学部）

2022年度，神経・筋・感覚機能検査学，専門教育科目（学部）

2022年度，臨地実習，専門教育科目（学部）

2022年度，臨床検査総合演習Ⅱ，専門教育科目（学部）

2022年度，臨床生理学，専門教育科目（学部）

2022年度，臨床生理学実習，専門教育科目（学部）

2022年度，臨床生理学演習，専門教育科目（学部）

2022年度，臨床生理検査学Ⅰ，専門教育科目（学部）

2022年度，細胞生理学特論，修士課程・博士前期課程

2022年度，医学研究基礎技術実習，博士一貫課程・博士後期課程

2022年度，顎口腔腫瘍病態学演習，博士一貫課程・博士後期課程

2022年度，医学・医療の世界－感染症から身を守る－，教養教育科目

2022年度，基礎ゼミナール【M保検査】，教養教育科目

2022年度，生物学の世界－生命の起源と進化－，教養教育科目

2021年度，神経・筋・感覚機能検査学，専門教育科目（学部）

2021年度，臨地実習，専門教育科目（学部）

2021年度，臨床検査総合演習Ⅱ，専門教育科目（学部）

2021年度，臨床生理学，専門教育科目（学部）

2021年度，臨床生理学実習，専門教育科目（学部）

2021年度，臨床生理学演習，専門教育科目（学部）

2021年度，医学研究基礎技術実習，博士一貫課程・博士後期課程

2021年度，顎口腔腫瘍病態学演習，博士一貫課程・博士後期課程

2021年度，医学・医療の世界－感染症から身を守る－，教養教育科目

2021年度，生物学の世界－生命の起源と進化－，教養教育科目

2020年度，免疫学，専門教育科目（学部）

2020年度，研究室研修，専門教育科目（学部）

2020年度，医学研究基礎技術実習，博士一貫課程・博士後期課程

2020年度，脳血管病態学実験実習，博士一貫課程・博士後期課程

2020年度，脳血管病態学演習，博士一貫課程・博士後期課程

2020年度，医学・医療の世界－感染症から身を守る－，教養教育科目

2020年度，基礎ゼミナール，教養教育科目

2020年度，生物学の世界－生命の起源と進化－，教養教育科目

2019年度，最新医学の現状（Ｒ），21世紀教育科目

2019年度，研究室研修，専門教育科目（学部）

2019年度，神経科学，専門教育科目（学部）

2019年度，大学院特別研究セミナー，博士一貫課程・博士後期課程

2019年度，医学・医療の世界－感染症から身を守る－，教養教育科目

2019年度，基礎ゼミナール，教養教育科目

2019年度，生物学の世界－生命の起源と進化－，教養教育科目

2018年度，最新医学の現状（Ｒ），21世紀教育科目

2018年度，生物の科学・技術（Ａ），21世紀教育科目

2018年度，PBL，専門教育科目（学部）

2018年度，研究室研修，専門教育科目（学部）

2018年度，神経科学，専門教育科目（学部）

2018年度，医学・医療の世界－感染症から身を守る－，教養教育科目

2018年度，生物学の世界－生命の起源と進化－，教養教育科目

2017年度，化学の基礎Ⅱ（Ｃ），21世紀教育科目

2017年度，最新医学の現状（Ｒ），21世紀教育科目

2017年度，生物の科学・技術（Ａ），21世紀教育科目

2017年度，PBL，専門教育科目（学部）

2017年度，研究室研修，専門教育科目（学部）

2017年度，神経科学，専門教育科目（学部）

2017年度，医学・医療の世界－感染症から身を守る－，教養教育科目

2017年度，生物学の世界－生命の起源と進化－，教養教育科目

2016年度，化学の基礎Ⅱ（Ｃ），21世紀教育科目

2016年度，最新医学の現状（Ｒ），21世紀教育科目

2016年度，生物の科学・技術（Ａ），21世紀教育科目

2016年度，研究室研修，専門教育科目（学部）

2016年度，神経科学，専門教育科目（学部）

2016年度，医学・医療の世界－感染症から身を守る－，教養教育科目

2016年度，生物学の世界－生命の起源と進化－，教養教育科目

2015年度，研究室研修，専門教育科目（学部）

2015年度，神経科学，専門教育科目（学部）

2015年度，特別研究セミナー，博士一貫課程・博士後期課程

2014年度，研究室研修，専門教育科目（学部）

2014年度，医学研究概論Ｉ，博士一貫課程・博士後期課程

2014年度，特別研究セミナー，博士一貫課程・博士後期課程

2013年度，PBL，専門教育科目（学部）

2013年度，研究室研修，専門教育科目（学部）

2013年度，神経科学，専門教育科目（学部）

2013年度，医学研究概論Ｉ，博士一貫課程・博士後期課程

2013年度，特別研究セミナー，博士一貫課程・博士後期課程

2012年度，PBL，専門教育科目（学部）

2012年度，研究室研修，専門教育科目（学部）

2012年度，神経科学，専門教育科目（学部）

2012年度，医学研究概論Ｉ，博士一貫課程・博士後期課程

2012年度，特別研究セミナー，博士一貫課程・博士後期課程

2011年度，PBL，専門教育科目（学部）

2011年度，神経科学，専門教育科目（学部）

2011年度，医学研究概論Ｉ，博士一貫課程・博士後期課程

2011年度，特別研究セミナー，博士一貫課程・博士後期課程

2009年度，基礎生物実習（血液），21世紀教育科目

2009年度，チュートリアル，専門教育科目（学部）

2009年度，研究室研修，専門教育科目（学部）

2008年度，基礎生物実習（血液），21世紀教育科目

2008年度，チュートリアル，専門教育科目（学部）

2008年度，研究室研修，専門教育科目（学部）

2007年度，基礎生物実習（血液），21世紀教育科目

2007年度，チュートリアル，専門教育科目（学部）

2007年度，研究室研修，専門教育科目（学部）