論文 - 三村 純正
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Phosphorylation of serine 349 of p62 in Alzheimer's disease brain.
Kunikazu Tanji, Yasuo Miki, Taku Ozaki, Atsushi Maruyama, Hidemi Yoshida, Junsei Mimura, Tomoh Matsumiya, Fumiaki Mori, Tadaatsu Imaizumi, Ken Itoh, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi
Acta neuropathologica communications 2 50 - 50 2014年05月
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Carnosic acid suppresses the production of amyloid-β 1-42 and 1-43 by inducing an α-secretase TACE/ADAM17 in U373MG human astrocytoma cells.
Hidemi Yoshida, Pengfei Meng, Tomoh Matsumiya, Kunikazu Tanji, Ryo Hayakari, Fei Xing, Liang Wang, Kazushi Tsuruga, Hiroshi Tanaka, Junsei Mimura, Kunio Kosaka, Ken Itoh, Ippei Takahashi, Tadaatsu Imaizumi
Neuroscience research 79 83 - 93 2014年02月
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Nrf2 activation is associated with Z-DNA formation in the human HO-1 promoter.
Atsushi Maruyama, Junsei Mimura, Nobuhiko Harada, Ken Itoh
Nucleic acids research 41 ( 10 ) 5223 - 5234 2013年05月
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Carnosic acid suppresses the production of amyloid-β 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells.
Pengfei Meng, Hidemi Yoshida, Tomoh Matsumiya, Tadaatsu Imaizumi, Kunikazu Tanji, Fei Xing, Ryo Hayakari, Junichi Dempoya, Tetsuya Tatsuta, Tomomi Aizawa-Yashiro, Junsei Mimura, Kunio Kosaka, Ken Itoh, Kei Satoh
Neuroscience research 75 ( 2 ) 94 - 102 2013年02月
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Carnosic acid suppresses the production of amyloid-β 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells.
Meng P, Yoshida H, Matsumiya T, Imaizumi T, Tanji K, Xing F, Hayakari R, Dempoya J, Tatsuta T, Aizawa-Yashiro T, Mimura J, Kosaka K, Itoh K, Satoh K
Neuroscience research 75 ( 2 ) 94 - 102 2013年02月
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Nrf2 in bone marrow-derived cells positively contributes to the advanced stage of atherosclerotic plaque formation.
Nobuhiko Harada, Koichi Ito, Tomonori Hosoya, Junsei Mimura, Atsushi Maruyama, Noriko Noguchi, Ken-Ichi Yagami, Naoki Morito, Satoru Takahashi, Jon M Maher, Masayuki Yamamoto, Ken Itoh
Free radical biology & medicine 53 ( 12 ) 2256 - 2262 2012年10月
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Methylation of the KEAP1 gene promoter region in human colorectal cancer.
Naoyuki Hanada, Takenori Takahata, Qiliang Zhou, Xulu Ye, Ruowen Sun, Jugoh Itoh, Atsushi Ishiguro, Hiroshi Kijima, Junsei Mimura, Ken Itoh, Shinsaku Fukuda, Yasuo Saijo
BMC cancer 12 66 - 66 2012年02月
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Synphilin-1-binding protein NUB1 is colocalized with nonfibrillar, proteinase K-resistant α-synuclein in presynapses in Lewy body disease.
Kunikazu Tanji他
Journal of neuropathology and experimental neurology 70 ( 10 ) 879 - 889 2011年10月
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Nrf2 regulates NGF mRNA induction by carnosic acid in T98G glioblastoma cells and normal human astrocytes.
Junsei Mimura他
Journal of Biochemistry 150 ( 2 ) 209 - 217 2011年08月
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The novel Nrf2-interacting factor KAP1 regulates susceptibility to oxidative stress by promoting the Nrf2-mediated cytoprotective response.
Atsushi Maruyama他
Biochemical Journal 436 ( 2 ) 387 - 397 2011年06月
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Nrf2 regulates ferroportin 1-mediated iron efflux and counteracts lipopolysaccharide-induced ferroportin 1 mRNA suppression in macrophages.
Nobuhiko Harada他
Archives of Biochemistry and Biophysics 508 ( 1 ) 101 - 109 2011年04月
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Edaravone and carnosic acid synergistically enhance the expression of nerve growth factor in human astrocytes under hypoxia/reoxygenation.
Hidemi Yoshida他
Neuroscience Research 69 ( 4 ) 291 - 298 2011年04月
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Edaravone and carnosic acid synergistically enhance the expression of nerve growth factor in human astrocytes under hypoxia/reoxygenation.
Yoshida H, Mimura J, Imaizumi T, Matsumiya T, Ishikawa A, Metoki N, Tanji K, Ota K, Hayakari R, Kosaka K, Itoh K, Satoh K
Neuroscience research 69 ( 4 ) 291 - 8 2011年04月
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Discovery of the negative regulator of Nrf2, Keap1: a historical overview.
Itoh K, Mimura J, Yamamoto M
Antioxidants & redox signaling 13 ( 11 ) 1665 - 78 2010年12月
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Suppression of AhR signaling pathway is associated with the down-regulation of UDP-glucuronosyltransferases during BBN-induced urinary bladder carcinogenesis in mice. （共著）
Iida K, Mimura J, Itoh K, Ohyama C, Fujii-Kuriyama Y, Shimazui T, Akaza H, Yamamoto M.
Journal of Biochemistry 147 ( 3 ) 353 - 360 2010年03月
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Role of Nrf2 and p62/ZIP in the neurite outgrowth by carnosic acid in PC12h cells. （共著）
Kosaka K, Mimura J, Itoh K, Satoh T, Shimojo Y, Kitajima C, Maruyama A, Yamamoto M, Shirasawa T.
Journal of Biochemistry 147 ( 1 ) 73 - 81 2010年01月
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＜Symposium III＞Role of Nrf2 in the neurotrophic action of the electrophiles
Itoh Ken, Kosaka Kunio, Mimura Junsei, Satoh Takumi
弘前医学 61 ( 0 ) S63 - 69 2010年
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＜Symposium V＞Edaravone and Nrf2-inducers as neuroprotective agents in human astrocytes exposed to hypoxia/reoxygenation
Yoshida Hidemi, Mimura Junsei, Imaizumi Tadaatsu, Matsumiya Tomoh, Ishikawa Akira, Metoki Norifumi, Tanji Kunikazu, Ota Ken, Kosaka Kunio, Itoh Ken, Satoh Kei
弘前医学 61 ( 0 ) S147 - 156 2010年
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Hypersensitivity of aryl hydrocarbon receptor-deficient mice to lipopolysaccharide-induced septic shock.
Sekine H, Mimura J, Oshima M, Okawa H, Kanno J, Igarashi K, Gonzalez FJ, Ikuta T, Kawajiri K, Fujii-Kuriyama Y
Molecular and cellular biology 29 ( 24 ) 6391 - 400 2009年12月
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Hypersensitivity of aryl hydrocarbon receptor-deficient mice to lipopolysaccharide-induced septic shock. （共著）
Hiroki Sekine, Junsei Mimura, Motohiko Oshima, Hiromi Okawa, Jun Kanno, Katsuhide Igarashi, Frank J. Gonzalez, Togo Ikuta, Kaname Kawajiri, and Yoshiaki Fujii-Kuriyama
Molecular and Cellular Biology 29 ( 24 ) 6391 - 6400 2009年10月