論文 - 橋本 勝
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Fentanyl-Type Antagonist of the μ-Opioid Receptor: Important Role of Axial Chirality in the Active Conformation.
Arita H, Tanaka R, Kikukawa S, Tomizawa T, Sakata H, Funada M, Tomiyama K, Hashimoto M, Tasaka T, Tabata H, Nakamura K, Makino K, Oshitari T, Natsugari H, Takahashi H
Journal of medicinal chemistry 67 ( 12 ) 10447 - 10463 2024年06月
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Proposal for structure revision of pinofuranoxin A through total syntheses of stereoisomers.
Ujiie K, Tanaka C, Arai M, Hashimoto M, Yoshida Y, Kawano T, Tamura S
Journal of natural medicines 78 ( 3 ) 608 - 617 2024年06月
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Stereoselective Preparation of the Tricyclic Hexasubstituted Spirocyclopropane Core of Cyclohelminthol X.
Hashimoto K, Maeda H, Hashimoto M
Organic letters 2024年04月
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In vitro synthesis of oryzamutaic acid H using recombinant L-lysine ε-dehydrogenase from Agrobacterium tumefaciens.
Horie Y, Uchikata M, Ueda S, Yamahira G, Hashimoto M, Sakamoto K, Ito H, Hamada S
Journal of biotechnology 385 42 - 48 2024年04月
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Isolation of Paraphaeoketones: A Plausible Biosynthetic Explanation for Paraphaeolactones via a Benzilic Acid Rearrangement Rather than a Favorskii Rearrangement.
Oinuma Y, Kanehara R, Maeda H, Nishikawa T, Konno K, Tanaka K, Hashimoto M
Journal of natural products 87 ( 4 ) 1159 - 1170 2024年03月
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"Fruiting Liquid" of Mushroom-Forming Fungi, A Novel Source of Bioactive Compounds - Fruiting-Body Inducer and HIF and Axl Inhibitors.
Wu J, Uchida K, Yoshikawa A, Hashimoto M, Kondo M, Nihei K, Ishii M, Choi JH, Miwa Y, Shoda C, Lee D, Nakai A, Kurihara T, D'Alessandro-Gabazza CN, Toda M, Yasuma T, Gabazza EC, Hirai H, Kawagishi H
Journal of agricultural and food chemistry 71 ( 36 ) 13338 - 13345 2023年09月
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“Fruiting Liquid”of Mushroom-Forming Fungi,A Novel Source of Bioactive Compounds−Fruiting-Body Inducer and HIF and Axl Inhibitors
J. Wu, K. Uchida, A. Yoshikawa, M. Hashimoto, M. Kondo, K. Nihei, M. Ishii, J.-H. Choi, Y. Miwa, C. Shoda, D. Lee, A. Nakai, T. Kurihara, C. N. D’Alessandro-Gabazza, M. Toda, T. Yasuma, E. C. Gabazza, H. Hirai, H. Kawagishi
Agricultural Food Chemistry 71 ( 36 ) 13338 - 13345 2023年08月
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HIV-1 Integrase Inhibitor, Dihydroobionin B, and the Investigation of Its Extraordinary Specific Rotation
K. Hashimoto, K. Kimura, K. Ishida, E. Morita, K. Tanaka. M. Hashimoto
Journal of Natural Products 86 ( 9 ) 2139 - 2144 2023年08月
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Pseudo-Enantiomeric Paraphaeolactones and Their Biosynthetic Derivatives from Paraphaeosphaeria sp. KT4192: A Proposition of a Favorskii Rearrangement for Their Biosynthesis
R. Kanehara, Y. Oinuma, H. Maeda, M. Okazaki, K. Konno, K. Tanaka, M. Hashimoto
Journal of Natural Products 86 ( 7 ) 1832 - 1843 2023年06月
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Novel Cyclopropyl Compounds, Cyclopropylvirgines A to G, from the Fruiting Bodies of Amanita Virgineoides
J. Wu, Y. Kamiishi, K. Shimozaki, M. Kondo, M. Hashimoto, J.-H. Choi, C. N D’Alessandro-Gabazza, M. Toda, T. Yasuma, E. C Gabazza, H. Hirai, H. Kawagishi
Bulletin of the Chemical Society of Japan 96 ( 6 ) 503 - 509 2023年05月
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Integrasone Derivatives Isolated from Lepteutypa sp. KT4162 and Their Anti-HIV-1 Integrase Activity
S. Miura, K. Ishida, K. Tanaka, E. Morita and M. Hashimoto
Journal of Natural Products 86 ( 4 ) 1019 - 1024 2023年05月
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Isolation of cyclohumulanoids from Daedaleopsis tricolor and their biosynthesis based on in silico simulations.
R. Kanehara, A. Tonouchi, K. Konno, H. Koshino, M. Hashimoto
Tetrahedron 123 133006 2022年08月
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Structural Determination, Total Synthesis, and Biological Activity of Iezoside, a Highly Potent Ca2+-ATPase Inhibitor from the Marine Cyanobacterium Leptochromothrix valpauliae
N. Kurisawa, A. Iwasaki, K. Teranuma, S. Dan, C. Toyoshima, M. Hashimoto, Kiyotake Suenaga
Journal of American Chemical Society 144 ( 24 ) 11019 - 11032 2022年07月
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Isolation, Identification, and DFT-based Conformational Analysis of Sesquikarahanadienone and its Congeners from Freshwater Dothideomycetes Neohelicascus aquaticus KT4120
Ayane Hayasaka, Kazuki Hashimoto, Katsuhiro Konno, Kazuaki Tanaka, Masaru Hashimoto
Bulletin of the Chemical Society of Japan 95 ( 5 ) 833 - 845 2022年05月
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Biochemistry-Guided Prediction of the Absolute Configuration of Fungal Reduced Polyketides
Takino, Junya, Kotani, Akari, Ozaki, Taro, Peng, Wenquan, Yu, Jie, Guo, Yian, Mochizuki, Susumu, Akimitsu, Kazuya, Hashimoto, Masaru, Ye, Tao, Minami, Atsushi, Oikawa, Hideaki
Angewandte Chemie International Edition 60 ( 43 ) 23403 - 23411 2021年08月
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Isolation and Structural Elucidation of Novel Fusicoccan Dehydroxypericonicin A from Roussoella sp.
Ayane Hayasaka, Kazuaki Tanaka, and Masaru Hashimoto
Biosci. Biotech. Biochem. 85 ( 8 ) 1798 - 1801 2021年08月
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Semipinacol rearrangement of a bicyclo [7.2. 0] undecane framework into a bicyclo [6.3. 0] undecane skeleton: A model study on the biosynthesis of seiridiasteriscane A
Osamu Ishibashi, Mami Nishiyama, Eunsang Kwon, Masaru Hashimoto, Shigefumi Kuwahara, Masaru Enomoto
Biosci. Biotech. Biochem. 85 ( 7 ) 1621 - 1627 2021年07月
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Cyclohumulanoid Sesquiterpenes from the Culture Broth of the Basidiomycetous Fungus Daedaleopsis tricolor
Ryuhi Kanehara, Akio Tonouchi, Katsuhiro Konno, and Masaru Hashimoto
Molecules 26 ( 14 ) 4364 2021年06月
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Decaspirones and Palmarumycins from Phaeoseptum sp. KT4106: Chirality Reinvestigation of Palmarumycins CP4a and CP5
Ryuhi Kanehara, Ayane Hayasaka, Kota Inose, Takeshi Okamura, Satomi Miura, Kazuaki Tanaka, and Masaru Hashimoto
Tetrahedron Lett. 92 132251 2021年06月
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Oxidative Ring Contraction by a Multifunctional Dioxygenase Generates the Core Cycloocatadiene in the Biosynthesis of Fungal Dimeric Anhydride Zopfiellin
Tetsuya ShiinaTaro OzakiYusuke MatsuShota NagamineChengwei LiuMasaru HashimotoAtsushi Minami, Hideaki Oikawa
Organic Letters 22 ( 5 ) 1997 - 2001 2020年02月
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Anti-Japanese Encephalitis Virus (JEV) Activity of Triterpenes and Flavonoids from Euphorbia hirta
Wilanfranco C. Tayone, Kotaro Ishida, Simon Goto, Janeth C. Tayone, Masashi Arakawa, Eiji Morita, Masaru Hashimoto
Philipp J. Sci. 149 ( 3 ) 603 - 613 2020年02月
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Identification of neomacrophorins isolated from Trichoderma sp. 1212-03 as proteasome inhibitors.
Uesugi S, Honmura Y, Nishiyama M, Kusakabe K, Tonouchi A, Yamashita T, Hashimoto M, Kimura K-i.
Bioorganic & Medicinal Chemistry 27 ( 24 ) 115161 2019年11月
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DFT calculation–assisted stereo‐structural assignment of arundifungin
Mami Nishiyama Akio Tonouchi Hayato Maeda Masaru Hashimoto
Chirality 32 ( 1 ) 17 - 31 2019年11月
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DFT計算支援による天然物のNMR解析
橋本勝、福士江里、Warren Hehre
日本核磁気共鳴学会機関紙 10 31 - 41 2019年11月
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Cyclopericodiol and Novel Chlorinated Melleins Isolated from Periconia macrospinosa KT3863
Kota Inose, Kazuaki Tanaka, Hiroyuki Koshino, Masaru Hashimoto
Tetrahedron 75 ( 35 ) 130470 2019年08月
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An Efficient Protocol for Accurately Calculating 13C Chemical Shifts of Conformationally Flexible Natural Products: Scope, Assessment and Limitations.
Warren Hehre, Phillip Klunzinger, Bernard Deppmeier, Andy Driessen, Noritaka Uchida, Masaru Hashimoto, Eri Fukushi, Yusuke Takata
Journal of Natural Products 82 ( 8 ) 2299 - 2306 2019年08月
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Cyclopericodiol and new chlorinated melleins isolated from Periconia macrospinosa KT3863.
Inose K, Tanaka K, Koshino H, Hashimoto, M
Tetrahedron Letters 75 ( 35 ) 130470 2019年07月
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Biosynthetic machinery of 6‐hydroxymellein derivatives leading to cyclohelminthols and palmaenones
Takahiro Ugai, Atsushi MInami, Shizuya Tanaka, Raro Ozaki, Chengwei Liu, Hideyuki Shigemori, Masaru Hashimoto, Hideaki Oikawa
ChemBioChem 20 ( 1 ) 1 - 9 2019年06月
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Neomacrophorin and Premacrophorin Congeners from Trichoderma sp. 1212-03
Mami NIshiyama, Hayato Maeda, Akito Tonouchi, Masaru Hashimoto
Tetrahedron 75 ( 22 ) 2993 - 3000 2019年05月
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Isolation of Peribysins O, P, and Q from Periconia macrospinosa KT3863 and Configurational Reinvestigation of Peribysin E Diacetate from Periconia byssoides OUPS-N133
2.Kota Inose, Kazuaki Tanaka, Takeshi Yamada, Hiroyuki Koshino, Masaru Hashimoto
Journal of Natural Products 2019年02月
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Structure-Activity Relationships of Trichothecenes against COLO201 Cells and Cochliobolus miyabeanus: The Role of 12-Epoxide and Macrocyclic Moieties
1.Manami Matsumoto, Mami Nishiyama, Hayato Maeda, Akio Tonouchi, Katsuhiro Konno, Masaru Hashimoto
Bioorganic and Medicinal Chemistry Letters 29 982 - 985 2019年02月
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Structure of two purple pigments, catechiopyranocyanidins A and B from the seed-coat of the small red bean, Vigna angularis
3.Yoshida, K.; Nagai, N.; Ichikawa, Y.; Goto, M.; Kazuma, K.; Oyama, K.-i.; Koga, K.; Hashimoto, M.; Iuchi, S.; Takaya, Y.; Kondo, T.,
Scientific Reports 9 1484 2019年02月
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Biosynthetic study of conidiation-inducing factor conidiogenone: heterologous production and cyclization mechanism of a key bifunctional diterpene synthase.
4.Shiina, T.; Nakagawa, K.; Fujisaki, Y.; Ozaki, T.; Liu, C.; Toyomasu, T.; Hashimoto, M.; Koshino, H.; Minami, A.; Kawaide, H.; Oikawa, H.
Biosci. Biotech. Biochem. 83 ( 2 ) 192 - 201 2019年02月
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Isolation of Peribysins O, P, and Q from Periconia macrospinosa KT3863, and Configurational Reinvestigation of Peribysin E Diacetate from Periconia byssoides OUPS-N133
Kota Inose, Kazuaki Tanaka, Takeshi Yamada, Hiroyuki Koshino, Masaru Hashimoto
J. Nat. Prod. 82 ( 4 ) 911 - 918 2019年
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Synthesis of Chiral Nonracemic α-Difluoromethylthio Compounds with Tetrasubstituted Stereogenic Centers via a Palladium-Catalyzed Decarboxylative Asymmetric Allylic Alkylation
Hiroya Kondo, Mayaka Maeno, Kenta Sasaki, Ming Guo, Masaru Hashimoto, Motoo Shiro, Norio Shibata
Organic Letters 20 ( 22 ) 7044 - 7048 2018年11月
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天然物構造決定におけるDFT計算の活用
橋本勝
有機合成化学協会誌 76 ( 8 ) 842 - 850 2018年08月
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リンゴ果実におけるマイコパラサイト現象の生物有機化学
橋本勝
日本農薬学会誌 43 ( 2 ) 101 - 108 2018年08月
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12-Deoxyroridin J and 12-Deoxyepiisororidin E from Calcarisporium arbuscular
Manami Matsumoto, Shizuya Tanaka, Akio Tonouchi, Masaru Hashimoto
Tetrahedron Letters 59 ( 21 ) 1992 - 1995 2018年05月
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Cyclohelminthols Y1-Y4 Metabolites Possessing Two Spirocyclopropanes in their Structure
Shizuya Tanaka, Kazuaki Tanaka, Hayato Maeda, Masaru Hashimoto
Journal of Organic Chemistry 83 ( 10 ) 5688 - 5697 2018年05月
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Stereochemical Correction and Total Structure of Roridin J
Manami Matsumoto, Atsushi Ito, Akio Tonouchi, Masaaki Okazaki, Masaru Hashimoto
Tetrahedron 73 ( 36 ) 5430 - 5435 2017年06月
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Cyclohelminthol X, a Hexa-substituted Spirocyclopropane from Helminthosporium velutinum yone96: Structural Elucidation, Electronic Circular Dichroism Analysis, and Biological Properties
Shizuya Tanaka, Yuna Honmura, Shota Uesugi, Eri Fukushi, Kazuaki Tanaka, Hayato Maeda, Ken-ichi Kimura, Tatsuo Nehira, Masaru Hashimoto
Journal of Organic Chemistry 82 ( 11 ) 5574 - 5582 2017年05月
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Neomacrophorin X, a [4.4.3]Propellane-typed Meroterpenoid from Trichoderma sp. 1212-03
Kazuaki Kusakabe, Yuna Honmura, Shota Uesugi, Akio Tonouchi, Hayato Maeda, Ken-ichi Kimura, Hiroyuki Koshino, and Masaru Hashimoto
Journal of Natural Products 80 ( 5 ) 1484 - 1492 2017年04月
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29 Practical Protocol for Calculationg <SUP>13</SUP>C Chemical Shifts for Conformationally Flexible Natural Products; Scope and Limitations (口頭発表の部)
Warren Hehre, Philip Klunzinger, Bernard Deppmeier, 内田 典孝, 橋本 勝, 福士 江里, 高田 祐輔
天然有機化合物討論会講演要旨集 59 ( 0 ) 169 - 174 2017年
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Homopetasinic acid isolated from Diaporthe sp. strain 1308-05
1.Atsushi Ito, Ikuya Kumagai, Miku Maruyama, Hayato Maeda, Akio Tonouchi, Tatsuo Nehira, Ken-ichi Kimura, and Masaru Hashimoto
Tetrahedron Letters 57 ( 10 ) 1117 - 1119 2016年01月
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Isolation, absolute structures, and biological properties of cyclohelminthols I–IV from Helminthosporium velutinum yone96
2.Yuna Honmura, Shota Uesugi, Hayato Maeda, Kazuaki Tanaka, Tatsuo Nehira, Ken-ichi Kimura, Masaaki Okazaki, Masaru Hashimoto
Tetrahedron 72 ( 10 ) 1400 - 1405 2016年01月
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Homojesterones: vinylogous analogues of jesterone from Helminthosporium velutinum TS28
3.Miki Arayama, Shota Uesugi, Kazuaki Tanaka, Hayato Maeda, Tatsuo Nehira, Ken-ichi Kimura, Masaru Hashimoto
Tetrahedron Letters 57 ( 7 ) 1031 - 1035 2015年12月
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4.Miki Arayama, Hayato Maeda, Kazuaki Tanaka, Noboru Takada, Tatsuo Nehira, Masaru Hashimoto
4.Miki Arayama, Hayato Maeda, Kazuaki Tanaka, Noboru Takada, Tatsuo Nehira, Masaru Hashimoto
Tetrahedron 71 ( 41 ) 7900 - 7905 2015年08月
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Isolation, ECD assisted structural analyses, biosynthetic discussions, and biological activities of epi-cochlioquinones D and its derivatives
2.Miki Arayama, Tatsuo Nehira, Hayato Maeda, Kazuaki Tanaka, Hisashi Miyagawa, Tamio Ueno, Seijiro Hosokawa, Masaru Hashimoto
Tetrahedron 71 ( 29 ) 4788 - 4794 2015年05月
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リンゴ果実上におけるマイコパラサイト現象の分子機構
橋本勝
有機合成化学協会誌 73 ( 3 ) 230 - 240 2015年03月
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Isotopic Differentiation Protocol, a Selective Extraction of C- and N-Terminal Ions in ESI-Ms/Ms De Novo Peptide Sequencing
Mako Fujii, Hiroshi Chiba, Noriko Tamayama, Saki Kanamaru, and Masaru Hashimoto
Natural Products Chemistry & Research 3 ( 1 ) 1000164 - 1000164 2015年01月
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Computation-Assisted Structural Elucidation of Epoxyroussoeone and Epoxyroussoedione Isolated from Roussoella japanensis KT1651
Yuna Honmura, Hiroto Takekawa, Kazuaki Tanaka, Hayato Maeda, Tatsuo Nehira, Warren Hehre, and Masaru Hashimoto
J. Nat. Products 2015年
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Relative and absolute structure of phomolide C
4.Ito, A.; Maeda, H.; Tonouchi, A.; Hashimoto, M.
Biosci. Biotech. Biochem, 2015年
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Lambertellin System, the mechanism for fungal replacement of Moniliniafructigena with Lambertellacorni-maris without competitive inhibition on ager media
Akane Hirose, Shinji Kudo, Takanori Murakami, Kazuaki Tanaka, Yukio Harada, Masaru Hashimoto
Bioorg. Med. Chem. 22 ( 8 ) 2489 - 2495 2014年03月
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Neomacrophorin I, II, and III, novel drimenyl cyclohexanes with hydroxylated butanoates from Trichoderma sp. 1212-03
Akane, Hirose, Hayato, Maeda, Akio, Tonouchi, Masaru Hashimoto
Tetrahedron 70 ( 7 ) 1458 - 1463 2014年01月
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リンゴ果実におけるマイコパラサイト現象の生物有機化学的研究
橋本勝
日本化学会生体機能関連部会ニュースレター 28 ( 3 ) 3 - 6 2013年12月
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PlipastatinとFengucinにおける構造混乱の終結
橋本勝
化学と生物 51 ( 12 ) 840 - 843 2013年12月
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7-b- and 10-b-Hydroxylated Congeners of CAF-603; Elucidation of Absolute Configuration of CAF-603 Family, and their SAR Studies in the Antifungal Activity
Hiroto Takekawa, Kazuaki Tanaka, Eri Fukushi, Koichi Matsuo, Tatsuo Nehira, Masaru Hashimoto
Tetrahedron Letters 69 ( 6 ) 1047 - 1051 2013年09月
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Roussoellols A and B, Tetracyclic Fusicoccanes from Roussoella hysterioides
Hiroto Takekawa, Kazuaki Tanaka, Eri Fukushi, Koichi Matsuo, Tatsuo Nehira, Masaru Hashimoto
Journal of Natural Products 76 ( 6 ) 1047 - 1051 2013年05月
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Structural corrections of photinides A, B and their novel derivatives
R. Yasumura; K. Tanaka.; T. Nehira; M. Hashimoto
Tetrahedron 38 ( 23 ) 7991 - 7996 2012年06月
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Termination of the structural confusion between plipastatin A1 and fengycin IX
M. Honma, K. Tanaka, K. Konno, K. Tsuge, T. Okuno, M. Hashimoto
Bioorg. Med. Chem. 20 3793 - 3798 2012年04月
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Absolute Stereochemistry of Altersolanol A and Alterporriols
S. Kanamaru, M. Honma, T. Murakami, T. Tsushima, S. Kudo, K. Tanaka, K. Nihei, T. Nehira, M. Hashimoto
Chirality 24 137 - 146 2011年12月
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Absolute Stereochemistry of Novel Isochromanone Derivatives from Leptosphaeria sp. KTC 727
W. C. Tayone, S. Kanamaru, M. Honma, K. Tanaka, T. Nehira, M. Hashimoto
Biosci. Biotech. Biochem, 75 ( 12 ) 2390 - 2393 2011年12月
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A novel bisretinoid of retina is an Adduct on Glycerophosphoetanolamine
K. Yamamoto, K. Yoon, K. Ueda, M. Hashimoto, J. R. Sparrow
Investigative Ophthalmology & Visual Science 52 ( 12 ) 9084 - 9090 2011年11月
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Syntheses of cellotriose and cellotetraose analogues as transition state mimics for mechanistic studies of cellulases
1. S. Noguchi, S. Takemoto, S. Kidokoro, K.. Yamamoto, M. Hashimoto
Bioorg. Med. Chem, 19 3812 - 3830 2011年05月
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Stereochemical investigations of isochromenone and isobenzofuranone isolated from Leptosphaeria sp. KTC 727
Wilanfranco T. C.; Honma, M.; Kanamaru S.; Noguchi, S.; Tanaka, K.; Nehira, T.; Hashimoto, M.
J. Nat. Products 74 ( 0 ) 425 - 429 2011年03月
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Stereochemical differentiation in the Simmons-Smith reaction for cyclopropanated glucopyranose derivatives as molecular probes for glycosidases
N. Akiyama, S. Noguchi, M. Hashimoto
Biosci. Biotech. Biochem 75 ( 7 ) 1380 - 1382 2011年03月
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Bunodosine 391: a new analgesic acylamino acid from the venom of the sea anemone Bunodosoma cangicum
4. Wilanfranco T. C.; Honma, M.; Kanamaru S.; Noguchi, S.; Tanaka, K.; Nehira, T.; Hashimoto, M.
J. Nat. Products 74 ( 0 ) 378 - 382 2011年03月
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Synthesis of a trigalacturonic acid analogue mimicking the expected transition state in the glycosidases
Yamamoto, K.; Noguchi, S.; Takada, N.; Miyairi, K.; Hashimoto, M.
Crabohydr. Res. 345 ( 0 ) 572 - 585 2009年12月
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Four Analogues of Spiroleptosphol isolated from Leptosphaeria doliolum
T. Murakami, T. Tsushima, N. Takada, K. Tanaka, K. Nihei, T. Miura, M. Hashimoto
Bioorg. Med. Chem. 19 ( 0 ) 1122 - 1125 2009年12月
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Novel Neofusapyrones Isolated from Verticillium dahliae as Potent Antifungal Substances
Honma, M.; Kudo, S.; Takada, N.; Miura, T.; Hashimoto, M.
Bioorg. Med. Chem. Lett. 20 ( 0 ) 709 - 712 2009年12月
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Absolute stereochemistry and conformational analysis of achaetolide isolated from Ophiobolus sp
Tayone, W. C.; Shindo, S.; Murakami, T.; Hashimoto, M.; Tanaka, K.; Takada, N.
Tetrahedron 65 ( 0 ) 7464 - 7467 2009年07月
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Isolation and absolute stereochemistry of optically active sydonic acid from from Glonium sp. (Hysteriales, Ascomycota)"
T. Murakami, T. Tsushima, N. Takada, K. Tanaka, K. Nihei, T. Miura, M. Hashimoto
Bioorg. Med. Chem. 19 ( NA ) 492 - 495 2009年03月
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Spartan Essentialを導入して ~演習講義「コンピュータ分子設計学」への展開
橋本勝
日本化学会情報化学部会誌 26 ( NA ) 106 - 112 2009年03月
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Syntheses of Lambertellols and Their Stable Analogues; Investigation of the Real Active Species in the Mycoparasitism by Lambertella Speciese
Nomiya, M., Murakami, T., Takada, N., Okuno, T., Harada, Y., Hashimoto, M.
J. Org. Chem 73 5039 - 5047 2008年07月
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Structure and Biosynthesis of Norneolambertellin Produced by Lambertella sp.1346
Hashimoto, M.; Tsushima, T.; Murakami, T.; Nomiya, M.; Takada, N.; Tanaka, K
Bioorg. Med. Chem. Lett. 18 ( 14 ) 4228 - 4231 2008年06月
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Rdc-enhanced NMR spectroscopy in structure elucidation of natural products/small molecules: Sucro-neolambertellin as a testcase
Schuetz, A.; Murakami, T.; Takada, N.; Junker, J.; Hashimoto, M.; Griesinger, C.
Angew. Chem. Int. Ed. 47 ( 11 ) 2032 - 2033 2008年02月
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Stimulation of the Biosynthesis of the Antibiotics Lambertellols by the Mycoparasitic Fungus Lambertella corni-maris under the Acidic Conditions Produced by Its Host Fungus in Vitro
Murakami, T.; Takada, N.; Harada, Y.; Okuno, T.; Hashimoto, M.
Biosci. Biotech. Biochem. 71 ( 7 ) 1230 - 1235 2007年07月
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An RNA polymerase inhibitor, cyclothiazomycin B1, and its isomer.
Hashimoto, M., Murakami, T., Funahashi, K.., Tokunaga, T., Nihei, K.., Okuno, T.,,Kimura, T., Naoki, H., Himeno, H.
Bioorg. Med. Chem, 14 ( 24 ) 8259 - 8270 2006年12月
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ピラノース環酸素を硫黄原子で置換したチオオリゴサッカリドの合成研究
橋本勝
有機合成化学協会誌 64 ( 7 ) 766 - 777 2006年07月
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Synthetic Studies of Oligogalacturonate as Molecular Probes for endo-PG1
M. Hashimoto, K., Yamamoto, M. Saito, K. Miyairi, T. Okuno,
ICOB-5 & ISCNP-25 IUPAC International conference on Biodiversity and Natural Products NA ( NA ) P41 - P41 2006年01月
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Isolation, structure determination, and biological properties of cyclothiazomycins B1 and B2
T. Murakami, T. Kimura T. Okuno, H. Himeno, M. Hashimoto
ICOB-5 & ISCNP-25 IUPAC International conference on Biodiversity and Natural Products NA ( NA ) P48 - P48 2006年01月
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Design, synthesis, and enzymatic property of a sulfur-substituted analogueof trigalacturonic acid
Yamamoto, K., Watanabe, N., Matsuda, H., Oohara, K., Araya, T., Hashimoto, M., Miyairi, K., Okazaki, I., Saito, M., Shimizu, T., Kato, H., Okuno, T.
Bioorg. Med. Chem, Lett. 15 ( 22 ) 4932 - 4935 2005年11月
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Isolation, structure elucidation, preparation,and biological properties of neolambertellin
Murakami, T., Hashimoto, M., Okuno, T.
Bioorg. Med. Chem, Lett. 15 ( 19 ) 4185 - 4188 2005年10月
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Synthetic studies on oligosaccharides composed of 5-thioglucopyranose units
Morii, Y., Matsuda, Y., Ohara, K., Hashimoto, M., Miyairi, K., Okuno, T.
Bioorg. Med. Chem. 13 ( 17 ) 5113 - 5144 2005年09月
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Lambertellol C, a labile and novel biosynthetic congener of lambertellols A and B
Murakami T., Sasaki A.., Fukushi E., Kawabata J., Hashimoto M., Okuno T.
Bioorg. Med. Chem. Lett., 15 ( 10 ) 2587 - 2590 2005年05月
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Optimization of isotope-labeling conditions for lambertellin based on isotope patterns observed by mass spectrometry
Murakami T., Sasaki A.., Fukushi E., Kawabata J., Hashimoto M., Okuno T.
Bioorg. Med. Chem. Lett. 15 ( 10 ) 2591 - 2594 2005年05月
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Pachyelasides A-D, Novel Molluscicidal Triterpene Saponins from Pachyelasma Tessmannii
Nihei K., YING B.-P., Murakami T., Matsuda H., Hashimoto M. & Kubo I.
J. Agric. Food Chem., 53 ( 3 ) 608 - 613 2005年01月
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Synthesis of thiosaccharides employing the Pummerer rearrangement of tetrahydrothiopyran oxides
Fujita J., Matsuda H., Yamamoto K., Morii Y., Hashimoto M., Okuno T.& Hashimoto K.
Tetrahedron 60 ( 32 ) 6829 - 6851 2004年08月
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Biosynthesis of Lambertellols Based on the High Specific Incorporation of the 13C-Labeled Acetates and Their Biological Properties
Murakami T., Takahashi Y., Fukushi E., Kawabata J., Hashimoto M., Okuno T.& Harada Y.
J, Am. Chem. Soc. 126 ( 30 ) 9214 - 9220 2004年07月
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Lambertellols A and B, Novel 3,4-Dihydronaphthalen-1(2H)-ones with Spiro-butenolide Produced by Lambertella sp.1346.
Murakami, T., Morikawa, Y., Hashimoto, M., Okuno, T. & Harada, Y.
Org. Lett. 6 ( 2 ) 157 - 160 2003年12月
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Pummerer rearrangement of 1-deoxy-5-thioglucopyranose oxides; novel synthesis of 5-thioglucopyranose derivatives.
Matsuda, H., Fujita, J., Morii, Y., Hashimoto, M., Okuno, T. & Hashimoto, K.
Tetrahedron Letters 44 ( 21 ) 4089 - 4093 2003年05月
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α-Selective Glycosylation with 5-thioglucopyranosyl Donnors; Synthesis of an Isomaltotetraoside mimic Composed of 5-thioglucopyranose Units.
Matsuda, H., Ohara, K., Morii, Y., Hashimoto, M., Miyairi, K. & Okuno, T.
Bioorg. Med. Chem. Lett. 13 ( 21 ) 1063 - 1066 2003年04月
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Synthetic studies of carzinophilin. Part 4: Chemical and biological properties of carzinophilin analogues.
Hashimoto, M., Matsumoto, M., Yamada, K. & Terashima,S.
Tetrahedron 59 ( 17 ) 3089 - 3097 2003年04月
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Synthetic studies of carzinophilin. Part 1: Synthesis of 2-methylidene-1-azabicyclo[3.1.0]hexane systems related to carzinophilin.
Hashimoto, M., Matsumoto, M. & Terashima, S.
Tetrahedron 59 ( 17 ) 3019 - 3040 2003年04月
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Synthetic studies of carzinophilin. Part 2: Synthesis of 3,4-dibenzyloxy-2-methylidene-1-azabicyclo[3.1.0]hexane systems corresponding to the C1-17 fragment of carzinophilin.
Hashimoto, M., Matsumoto, M. & Terashima, S.
Tetrahedron 59 ( 17 ) 3041 - 3062 2003年04月
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Synthetic studies of carzinophilin. Part 3: Synthetic approach toward carzinophilin and successful synthesis of 13-O-desacetyl-12,13-di-O-benzyl-4-O-methylcarzinophilin
Hashimoto, M., Sugiura, M. & Terashima, S.
Tetrahedron 59 ( 17 ) 3063 - 3087 2003年04月
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b-Selective Glycosylation of 5-Thioglucopyranose Derivatives: Synthesis of b-(1-6)Linked 5'-Thioglucopyranosyl Disaccharides.
Ohara, K., Matsuda, H., Hashimoto, M., Miyairi, K. & Okuno, T
Chemistry Letters 2002 ( 00 ) 626 - 627 2002年01月
-
Total Synthesis of Both Enantiomers of Dictyochromenol and their (Z)-Isomers.
Aoki, K., Takahashi, M., Hashimoto, M., Okuno, T., Kurata, K. & Suzuki, M.
Biosci. Biotech. Biochem. 66 ( 00 ) 1915 - 1924 2002年01月
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Novel Preparation of (2-Azidomethyl)benzoic Acid and an Application as a Protective Group
Matsuda, H., Hashimoto, M. & Okuno, T.
Syn. Commun. 32 ( 00 ) 347 - 345 2002年01月
-
100(P-48) 環内に硫黄原子を有するオリゴサッカリドの合成研究(ポスター発表の部)
松田 寛子, 大原 啓一郎, 藤田 純次, 橋本 勝, 宮入 一夫, 奥野 智旦
天然有機化合物討論会講演要旨集 44 ( 0 ) 587 - 592 2002年
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Fluorescent Pigments if the Retinal Pigment Epithelium and Age-related Macular Degeneration.
Ben-Shabat, S., Craig, P., A, Hashimoto, M., Liu, J., Koji, N. & Sparrow, J.
Bioorg. Med. Chem. Lett. 11 ( 00 ) 1533 - 1540 2001年01月
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Design and Synthesis of a novel Photoaffinity Taxoid as a Potential Probe for the Study of Paclitaxel-microtubules Interactions.
Lin, S., Fang, K., Hashimoto, M., Nakanishi, K. & Ojima, I.
Tetrahedron Lett., 41 ( 00 ) 4287 - 4290 2000年01月
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A2E, a Lipofuscin Fluorophore, in Human Retinal Pigmented Epithelial Cells in Culture
Sparrow, J., Craig, P., A, Hashimoto, M. & Nakanishi, K.
IVOS 40 ( 00 ) 2988 - 1995 2000年01月
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Enantioselective Binding of an 11-cis-Locked Cyclopropyl Retinal. The Conformation of Retinal in Bovine Rhodopsin
Hashimoto, M. & Fujimoto, Y.
Syn. Commun. 29 ( 00 ) 3793 - 3797 1999年01月
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Preparation and Biological Properties of Biotinylated PhTX Derivatives.
Hashimoto, M., Liu, Y., Fang, K., Li, H.-y. & Nakanishi, K.
Bioorg. Med. Chem. 7 ( NA ) 1181 - 1194 1999年01月
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A Stereoselective Synthesis of 4-O-methyl-13-Desacetyl-12,13-di-O-benzylcarzinophilin.
Hashimoto, M. & Terashima, S.
Heterocycles 47 ( NA ) 59 - 64 1998年01月
-
Isolation and One-step Preparation of A2E and Iso-A2E, Fluorophores from Human Retinal Epithelium.
Craig, P., A, Hashimoto, M., Nakanishi, K., Dillon, J. & Sparrow, J.
Proc. Nat. Acd. Sci. USA, 95 ( NA ) 14609 - 14613 1998年01月
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A Bifunctional Photoaffinity Probe for Ligand/Receptor Interaction Studies.
Fang, K.; Hashimoto, M.; Jockusch, S.; Turro, N. J.; Nakanishi, K.
J, Am. Chem. Soc., 120 ( NA ) 8543 - 8544 1998年01月
-
Total Synthesis of an Enantiomeric Pair of Fr900482. 2. Synthesis of the Aromatic and Optically Active Aliphatic Segments.
Yoshino, T., Nagata, Y., Itoh, E., Hashimoto, M., Katoh, T. & Terashima, S.
Tetrahedron 53 ( NA ) 10239 - 10252 1997年01月
-
Total Synthesis of Natural (+)-FR-900482. 2. Efficient Synthesis of the Aromatic and Optically Active Aliphatic Fragments.
Yoshino, T., Nagata, Y., Itoh, E., Hashimoto, M., Katoh, T. & Terashima, S.
Tetrahedron Letters 37 ( NA ) 3475 - 3478 1996年01月
-
Novel Synthesis of (+)-Hydantocidin Based on the Plausible Biosynthetic Pathway.
Nakajima, N., Matsumoto, M., Kirihara, M., Hashimoto, M., Katoh, T. & Terashima, S.
Tetrahedron 52 ( NA ) 1177 - 1194 1996年01月
-
One-step Synthesis of (5)-Epi-Hydantocidin.
Nakajima, N., Kirihara, M., Matsumoto, M., Hashimoto, M., Katoh, T. & Terashima, S.
Heterocycle 42 ( NA ) 503 - 508 1996年01月
-
Synthetic Studies on the Key Component of the New Generation of Quinolonecarboxylic Acid, DU-6859. 2. Asymmetric Synthesis of (1R,2S)-2-Fluorocyclopropylamine.
Tamura, O., Hashimoto, M., Kobayashi, Y., Katoh, T., Nakatani, K., Kamada, M., Hayakawa, I., Akiba, T. & Terashima, S.
Tetrahedron 50 ( NA ) 3905 - 3914 1994年01月
-
Synthesis, Chemical Reactivity, and Cytotoxicity of Carzinophilin Congeners Carrying a 2-(Acylamino-1-alkoxycarbonyl)methylidene-1-azabicyclo[3.1.0]hexane System.
Hashimoto, M., Matsumoto, M., Yamada, K. & Terashima, S.
Tetrahedron Letters 35 ( NA ) 2207 - 2210 1994年01月
-
A Stereoselective Synthesis of a Novel Model Compound of Carzinophilin Carrying the C6-C13 Unit with Correct Stereochemistry.
Hashimoto, M. & Terashima, S.
Chemistry Letters 1994 ( NA ) 1101 - 1104 1994年01月
-
A Novel Synthesis of the C1-C17 Fragment of Carzinophilin.
Hashimoto, M. & Terashima, S.
Tetrahedron Letters 35 ( NA ) 9409 - 9412 1994年01月
-
Synthetic Studies on the Key Component of the New Generation of Quinolonecarboxylic Acid, DU-6859. 1. Synthesis of (1R,2S)-2-Fluorocyclopropylamine by the Use of Optical Resolution.
Tamura, O., Hashimoto, M., Kobayashi, Y., Katoh, T., Nakatani, K., Kamada, M., Hayakawa, I., Akiba, T. & Terashima, S.
Tetrahedron 50 ( NA ) 3889 - 3904 1994年01月
-
Asymmetric Synthesis of (1R,2S)-2-Fluorocyclopropylamine. the Key Intermediate of the New Generation of quinolonecarboxylic acid, DU-6859.
Tamura, O., Hashimoto, M., Kobayashi, Y., Katoh, T., Nakatani, K., Kamada, M., Hayakawa, I., Akiba, T. & Terashima, S.
Tetrahedron Letters 33 ( NA ) 3487 - 3490 1992年01月
-
Chemical Reactivity, and Cytotoxicity of 2-Bis(alkoxycarbonyl)methylidene-1-azabicyclo[3.1.0]hexane Systems Related to Antitumor Antibiotic Carzinophilin A.
Hashimoto, M., Yamada, K. & Terashima, S.
Chemistry Letters 1992 ( NA ) 975 - 978 1992年01月
-
Synthesis and Optical Resolution of dl-cis-2-Fluorocyclopropylamine, the Key Component of the New Generation of Quinolonecarboxylic acid, DU-6859.
Tamura, O., Hashimoto, M., Kobayashi, Y., Katoh, T., Nakatani, K., Kamada, M., Hayakawa, I., Akiba, T. & Terashima, S.
TetrahedronLetters 34 ( NA ) 3483 - 3486 1992年01月
-
Total Synthesis of the meso-Triterpene Polyether Teurilene.
Hashimoto, M., Harigaya, H., Yanagiya, M. & Shirahama, H.
J. Org. Chem. 56 ( NA ) 2299 - 2311 1991年01月
-
Total Synthesis of (+)-Thyrsiferol, (+)-Thyrsiferyl 23-Acetate, and Teurilene.
Hashimoto, M., Kan, T., Nozaki, K., Yanagiya, M., Shirahama, H. & Matsumoto, T.
J. Org. Chem. 55 ( NA ) 5088 - 5107 1990年01月
-
The Absolute Configuration of 4,6-decadiyne-1,3,8-triol Isolated from Gymnopiliun spectabilis.
Hashimoto, M., Yanagiya, M., Okuno, T. & Shirahama, H.
Bull. Chem. Soc. Jpn. 62 ( NA ) 2751 - 2752 1989年01月
-
Total Synthesis of (+)-Thyrsiferol and (+)-Venustatriol
Hashimoto, M., Kan, T., Nozaki, K., Yanagiya, M., Shirahama, H. & Matsumoto, T.
Tetrahedron Letters 29 ( 00 ) 1143 - 1144 1988年01月
-
A Short Step Synthesis of Teurilene. Stereocontrolled Sequential Double Cyclization of the C30-Tetraenetetraol to the Tandem Tetrahydrofurane System.
Hashimoto, M., Harigaya, H., Yanagiya, M. & Shirahama, H.
Tetrahedron Letters 29 ( NA ) 5947 - 5948 1988年01月
-
Effective Deprotection of 2-(Trimethylsilylethoxy)methylated Alcohols (SEM Ethers). Synthesis of Thyrsiferyl-23 Acetate.
Kan, T., Hashimoto, M., Yanagiya, M. & Shirahama, H.
Tetrahedron Letters 29 ( NA ) 5417 - 5418 1988年01月
-
Total Synthesis of meso-Triterpene Ether, Teurilene
Hashimoto, M., Yanagiya, M. & Shirahama, H.
Chemistry Letters 1988 ( 00 ) 645 - 646 1988年01月
-
Synthesis of A-B-C-ring Segment of Thyrsiferol: Construction of a Strained Tetrahydropyrane Ring Existing as a Boat Form.
Hashimoto, M., Kan, T., Yanagiya, M., Shirahama, H. & Matsumoto, T.
Tetrahedron Lettres 28 5665 - 5668 1987年01月