Papers - MAEDA HAYATO
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Apple pomace extract induces type II collagen and proteoglycan production in human chondrocytes
Nanashima Naoki, Maeda Hayato, Nakajima Akira, Nishizuka Makoto, Narumi Tsuyoshi, Ichita Junji, Itoku Koh
Food Science and Technology Research advpub ( 0 ) 2026.6
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Isopropylated phenyl phosphate, an organophosphorus flame retardant, induces depressive- and anxiety-like behaviors in mice.
Inoue Y, Chiba S, Maeda H, Nakajima A
Toxicology and applied pharmacology 510 117758 2026.5
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Antifungal Cyclic Peptides Dinemasporins from the Culture of Dinemasporium parastrigosum KT4144.
Kirisawa K, Kanehara R, Tanaka K, Sato S, Maeda H, Konno K, Minami A, Hashimoto M
Journal of natural products 2026.3
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Funginocarterphenyls A-C: Thiazole-Containing p-Terphenyls from Paulkirkia sp. KT4190.
Kanehira R, Maeda H, Tanaka K, Hashimoto M
Bioscience, biotechnology, and biochemistry 2026.3
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Nutty-flavour compound 3-methylbutanal production in milk by Lactococcus cremoris: biosynthesis pathway and role of pyruvate dehydrogenase.
Hayashizaki N, Ogura A, Maeda H, Tsuda H
The Journal of dairy research 1 - 8 2026.1
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Phytochemical composition, antioxidant, and antibacterial potential of three brown seaweeds from Japan
Afrin, F; Dulal, MA; Maeda, H; Rasul, MG; Shah, AKMA; Yuan, CH
FOOD AND HUMANITY 5 2025.12
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Immunostimulatory activity of blackcurrant polysaccharide hydrolysate in mouse macrophage-like RAW264.7 cells
Maeda Hayato, Hayashi Misaki, Konishi Teruko, Matsukawa Nanaka, Tahara Momoka, Daimon Riku, Takata Ryoji, Kato Yoji
Food Science and Technology Research 32 ( 2 ) 191 - 202 2025.11
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Total synthesis of quasi-symmetric dihydrofuran lignans (-)-ribesin A and B isolated from<i> Ribes</i><i> nigrum</i> leaves
Horio, K; Maeda, H; Horie, K; Nanashima, N; Nihei, KI
TETRAHEDRON 181 2025.8
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Isolation and Identification of Xanthone, Benzofuran, and Spirolactone Derivatives from Dinemasporium parastrigosum KT4144 and Their Plausible Biosynthetic Pathways.
Kirisawa K, Sato S, Minami A, Maeda H, Tanaka K, Hashimoto M
Journal of natural products 2025.5
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Isolation of 6,7-iso-Felinone A: A Configurational Reinvestigation of Related Fungal Metabolites.
Kanehira R, Abe H, Ito H, Kanehara R, Maeda H, Tanaka K, Hashimoto M
Journal of natural products 2025.3
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COMBINED EFFECTS OF VACUUM PACKAGING AND MORINGA LEAF POWDER ON THE QUALITY AND STORABILITY OF NILE TILAPIA (Oreochromis niloticus) PICKLE DURING STORAGE
Akter, R; Shah, AKMA; Maeda, H; Hossain, MA; Yuan, CH; Rasul, MG
JOURNAL OF MICROBIOLOGY BIOTECHNOLOGY AND FOOD SCIENCES Vol. 14 ( No. 5 ) 2025.2
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Editorial: Transdisciplinary communication for sustainable food systems
Watabe, S; Hu, YQ; Maeda, H; Yuan, CH
FRONTIERS IN SUSTAINABLE FOOD SYSTEMS 9 2025.2
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Heat-killed Lactococcus lactis subsp. lactis L8 ameliorates dextran sulfate sodium-induced colitis in mice
Kawaguchi Shogo, Chinda Daisuke, Ota Shinji, Tonouchi Akio, Maeda Hayato, Miura Kazuhide, Soma Go, Hiraga Hiroto, Ueno Kayo, Niioka Takenori, Tachizaki Mayuki, Seya Kazuhiko, Imaizumi Tadaatsu, Fukuda Shinsaku, Sakuraba Hirotake
Journal of Clinical Biochemistry and Nutrition advpub ( 0 ) 2024.12
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Triantaspirols A-C and Paraphaeolactone Cs from Paraphaeosphaeria sp. KT4192: Sensitivity of CP3 in Distinguishing Close NMR Signals.
Kanehara R, Oinuma Y, Maeda H, Tanaka K, Hashimoto M
2024.10
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Detecting Phytoestrogens and Mammalian Estrogens in Blackcurrants (Ribes nigrum)
Nanashima N, Horie K, Maeda H, Kato Y.
34 ( 5 ) 1196 - 1199 2024.10
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Metabolic syndrome preventive effects of fucoxanthin and paprika carotenoids
Maeda Hayato
VITAMINS 98 ( 9 ) 421 - 426 2024.9
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Highly Functionalized Spirobisnaphthalenes from Roussoella sp. KT4147.
Taichiro Tokizaki, Ryuhi Kanehara, Hayato Maeda, Kazuaki Tanaka, Masaru Hashimoto
Journal of natural products 87 ( 7 ) 1798 - 1807 2024.7
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Apple Pomace Extract Induces Cell Proliferation and Increases Type I Collagen and Hyaluronan Production in Human Skin Fibroblasts In Vitro.
Naoki Nanashima, Hayato Maeda, Akira Nakajima, Makoto Nishizuka, Tsuyoshi Narumi, Junji Ichita, Koh Itoku
Plant foods for human nutrition (Dordrecht, Netherlands) 2024.7
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Stereoselective Preparation of the Tricyclic Hexasubstituted Spirocyclopropane Core of Cyclohelminthol X
Kazuki Hashimoto, Hayato Maeda, Masaru Hashimoto
Organic Letters 2024.4
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Isolation of Paraphaeoketones: A Plausible Biosynthetic Explanation for Paraphaeolactones via a Benzilic Acid Rearrangement Rather than a Favorskii Rearrangement.
Oinuma Y, Kanehara R, Maeda H, Nishikawa T, Konno K, Tanaka K, Hashimoto M
Journal of natural products 2024.3
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Ishimozuku (Sphaerotrichia firma) lipids containing fucoxanthin suppress fatty liver and improve short chain fatty acid production in obese model mice
Masaki Shibata, Satoru Fukuda, Masaru Terasaki, Hayato Maeda
Frontiers in Sustainable Food Systems 7 2024.1
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Apple Pomace Extract Improves MK-801-Induced Memory Impairment in Mice
Ayako Watanabe, Minori Shimada, Hayato Maeda, Tsuyoshi Narumi, Junji Ichita, Koh Itoku, Akira Nakajima
Nutrients 16 ( 2 ) 194 - 194 2024.1
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Evaluation of eating quality of white rice using Raman spectroscopy with multivariate analysis
Sohei Yamada, Kohei Saito, Hayato Maeda, Shinichiro Kanda, Toyokazu Uemura, Takayo Ogawa, Satoshi Wada, Yasutaka Hanada
Journal of Raman Spectroscopy 1 - 7 2023.12
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Fucoxanthin Inhibits Development of Sigmoid Colorectal Cancer in a PDX Model With Alterations of Growth, Adhesion, and Cell Cycle Signals.
Terasaki M, Tsuruoka K, Tanaka T, Maeda H, Shibata M, Miyashita K, Kanemitsu Y, Sekine S, Takahashi M, Yagishita S, Hamada A
Cancer genomics & proteomics 20 ( 6suppl ) 686 - 705 2023.12
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Effects of extraction techniques on antioxidant and antibacterial activity of stevia (Stevia rebaudiana Bertoni) leaf extracts
A. Chakma, F. Afrin, M.G. Rasul, H. Maeda, C. Yuan, A.K.M.A. Shah
Food Chemistry Advances 3 ( 100494 ) 2023.10
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Effects of different tomato products on the lipid oxidation, color, and texture of uncured cooked pork sausages in storage
Mikami Nana, Yamashiro Yoshitaka, Nagaoka Shiho, Akamatsu Yuzuki, Maeda Hayato, Shimada Kenichiro
Food Science and Technology Research 29 ( 5 ) 433 - 440 2023.9
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Anticancer Effects of Fucoxanthin in a PDX Model of Advanced Stage Pancreatic Cancer with Alteration of Several Multifunctional Molecules
Masaru Terasaki, Sally Suzuki, Takuji Tanaka, Hayato Maeda, Masaki Shibata, Kazuo Miyashita, Yasuhiro Kuramitsu, Junichi Hamada, Tohru Ohta, Shigehiro Yagishita, Akinobu Hamada, Yasunari Sakamoto, Susumu Hijioka, Chigusa Morizane, Mami Takahashi
Onco 3 ( 4 ) 217 - 236 2023.9
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Mouse Model of Anti-Obesity Effects of Blautia hansenii on Diet-Induced Obesity.
Shibata M, Ozato N, Tsuda H, Mori K, Kinoshita K, Katashima M, Katsuragi Y, Nakaji S, Maeda H
Current issues in molecular biology 45 ( 9 ) 7147 - 7160 2023.8
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Pseudo-Enantiomeric Paraphaeolactones and Their Biosynthetic Derivatives from Paraphaeosphaeria sp. KT4192: A Proposition of a Favorskii Rearrangement for Their Biosynthesis.
Kanehara R, Oinuma Y, Maeda H, Okazaki M, Konno K, Tanaka K, Hashimoto M
Journal of natural products 2023.6
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Anthocyanin-rich blackcurrant extract improves long-term memory impairment and emotional abnormality in senescence-accelerated mice.
Shimada M, Maeda H, Nanashima N, Yamada K, Nakajima A
Journal of food biochemistry 46 ( 10 ) e14295 2022.10
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Fucoxanthinol Promotes Apoptosis in MCF-7 and MDA-MB-231 Cells by Attenuating Laminins–Integrins Axis
A Yasuda, M. Wagatsuma, W. Murase, A. Kubota, H. Kojima, T. Ohta, J. Hamada, H. Maeda, M. Terasaki
2 ( 3 ) 145 - 163 2022.7
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Requirement of CLIC4 Expression in Human Colorectal Cancer Cells for Sensitivity to Growth Inhibition by Fucoxanthinol.
Yokoyama R, Kushibiki A, Yamada S, Kubota A, Kojima H, Ohta T, Hamada J, Maeda H, Mutoh M, Terasaki M
Cancer genomics & proteomics 19 ( 4 ) 428 - 444 2022.7
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A Biscuit Containing Fucoxanthin Prevents Colorectal Carcinogenesis in Mice.
Terasaki M, Murase W, Kamakura Y, Kawakami S, Kubota A, Kojima H, Ohta T, Tanaka T, Maeda H, Miyashita K, Mutoh M
74 ( 10 ) 3651 - 3661 2022.6
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Inducible Systemic Gcn1 Deletion in Mice Leads to Transient Body Weight Loss upon Tamoxifen Treatment Associated with Decrease of Fat and Liver Glycogen Storage.
Liu J, Kasai S, Tatara Y, Yamazaki H, Mimura J, Mizuno S, Sugiyama F, Takahashi S, Sato T, Ozaki T, Tanji K, Wakabayashi K, Maeda H, Mizukami H, Shinkai Y, Kumagai Y, Tomita H, Itoh K
International journal of molecular sciences 23 ( 6 ) 2022.3
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Fucoxanthin Prevents Pancreatic Tumorigenesis in C57BL/6J Mice That Received Allogenic and Orthotopic Transplants of Cancer Cells
Murase Wataru, Kamakura Yukino, Kawakami Serina, Yasuda Ayaka, Wagatsuma Momoka, Kubota Atsuhito, Kojima Hiroyuki, Ohta Tohru, Takahashi Mami, Mutoh Michihiro, Tanaka Takuji, Maeda Hayato, Miyashita Kazuo, Terasaki Masaru
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 ( 24 ) 13620 2021.12
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Potential Vasculoprotective Effects of Blackcurrant (Ribes nigrum) Extract in Diabetic KK-Ay Mice.
Horie K, Maeda H, Nanashima N, Oey I
Molecules (Basel, Switzerland) 26 ( 21 ) 2021.10
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Comparative Analysis of Nutritional Compounds in Frozen Farmed Scallop and Bottom-Cultured Japanese Scallop in Mutsu Bay
Transactions of the Japan Society of Refrigerating and Air Conditioning Engineers 38 ( 3 ) 269 - 276 2021.9
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Suppression of C-C chemokine receptor 1 is a key regulation for colon cancer chemoprevention in AOM/DSS mice by fucoxanthin.
Masaru Terasaki, Shion Ono, Saki Hashimoto, Atsuhito Kubota, Hiroyuki Kojima, Tohru Ohta, Takuji Tanaka, Hayato Maeda, Kazuo Miyashita, Michihiro Mutoh
The Journal of nutritional biochemistry 99 108871 - 108871 2021.9
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Promotion of export and market evaluation of salmon trout from Aomori prefecture, Japan
Journal of the Japan Society for Intellectual Production 17 ( 2 ) 113 - 125 2021.6
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Quantitative prediction of a functional ingredient in apple using Raman spectroscopy and multivariate calibration analysis
Shinsaku Tsuyama, Akinori Taketani, Takeharu Murakami, Michio Sakashita, Saki Miyajima, Takayo Ogawa, Satoshi Wada, Hayato Maeda, Yasutaka Hanada
Applied Physics B 127 92 2021.5
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Fucoxanthin and Colorectal Cancer Prevention.
Masaru Terasaki, Atsuhito Kubota, Hiroyuki Kojima, Hayato Maeda, Kazuo Miyashita, Chikara Kawagoe, Michihiro Mutoh, Takuji Tanaka
Cancers 13 ( 10 ) 2379 - 2379 2021.5
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Effect of Fucoxanthinol on Pancreatic Ductal Adenocarcinoma Cells from an N-Nitrosobis(2-oxopropyl)amine-initiated Syrian Golden Hamster Pancreatic Carcinogenesis Model
MASARU TERASAKI, YUSAKU NISHIZAKA, WATARU MURASE, ATSUHITO KUBOTA, HIROYUKI KOJIMA, MARESHIGE KOJOMA, TAKUJI TANAKA, HAYATO MAEDA, KAZUO MIYASHITA, MICHIHIRO MUTOH, MAMI TAKAHASHI
Cancer Genomics - Proteomics 18 ( 3 Suppl ) 407 - 423 2021.3
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Fucoxanthin Prevents Colorectal Cancer Development in Dextran Sodium Sulfate-treated Apc<sup>Min/+</sup> Mice
Terasaki, M., Hamoya, T., Kubota, A., Kojima, H., Tanaka, T., Maeda, H., Miyashita, K., Mutoh, M.
Anticancer research 41 ( 3 ) 1299 - 1305 2021.3
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Fucoxanthinol Induces Apoptosis in a Pancreatic Intraepithelial Neoplasia Cell Line
Terasaki, M., Inoue, T., Murase, W., Kubota, A., Kojima, H., Kojoma, M., Ohta, T., Maeda, H., Miyashita, K., Mutoh, M., Takahashi, M.
Cancer Genomics and Proteomics 18 ( 2 ) 133 - 146 2021.3
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Alteration of fecal microbiota by fucoxanthin results in prevention of colorectal cancer in AOM/DSS-treated mice.
Masaru Terasaki, Osamu Uehara, Shinya Ogasa, Taishi Sano, Atsuhito Kubota, Hiroyuki Kojma, Takuji Tanaka, Hayato Maeda, Kazuo Miyashita, Michihiro Mutoh
Carcinogenesis 42 ( 2 ) 210 - 219 2021.2
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A Marine Carotenoid of Fucoxanthinol Accelerates the Growth of Human Pancreatic Cancer PANC-1 Cells
Masaru Terasaki , Shouta Takahashi , Ryuta Nishimura , Atsuhito Kubota , Hiroyuki Kojima , Tohru Ohta , Junichi Hamada , Yasuhiro Kuramitsu , Hayato Maeda , Kazuo Miyashita , Mami Takahashi, Michihiro Mutoh
Nutrition and Cancer 2021 1 - 16 2021.2
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Blackcurrant ( Ribes nigrum L.) Extract Exerts Potential Vasculoprotective Effects in Ovariectomized Rats, Including Prevention of Elastin Degradation and Pathological Vascular Remodeling
Kayo Horie, Naoki Nanashima, Hayato Maeda, Toshiko Tomisawa, Indrawati Oey
Nutrients 13 ( 2 ) 560 - 560 2021.2
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Ethnomedicinal Knowledge Verification for the Antidiarrheal and Antioxidant Effects of Rhus chinensis Mill. Fruits with Identification of Thirty Constituents
Chandra Mohini Nemkul, Gan B Bajracharya, Hayato Maeda, Ila Shrestha
Pharmacognosy Journal 13 ( 1 ) 37 - 43 2021.1
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Dietary Alaska pollock protein attenuates liver steatosis and alters gut microbiota in leptin-deficient ob/ob mice
H Maeda, R Hosomi, T Yokoyama, Y Ikeda, A Nishimoto, G Tanaka, T Shimono, S Kanda, T Nishiyama, M Yoshida, K Fukunaga
Journal of Functional Foods 75 104266 2020.11
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Continuity of Tumor Microenvironmental Suppression in AOM/DSS Mice by Fucoxanthin May Be Able to Track With Salivary Glycine.
Masaru Terasaki, Ryota Kimura, Atsuhito Kubota, Hiroyuki Kojima, Takuji Tanaka, Hayato Maeda, Kazuo Miyashita, Michihiro Mutoh
In vivo (Athens, Greece) 34 ( 6 ) 3205 - 3215 2020.11
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Maillard Reaction Intermediates and Related Phytochemicals in Black Garlic Determined by EPR and HPLC Analyses.
Kouichi Nakagawa, Hayato Maeda, Yoshifumi Yamaya, Yudai Tonosaki
Molecules (Basel, Switzerland) 25 ( 19 ) E4578 2020.10
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Effects of CLIC4 on Fucoxanthinol-Induced Apoptosis in Human Colorectal Cancer Cells
R Yokoyama, H Kojima, R Takai, T Ohta, H Maeda, K Miyashita, M Mutoh, M Terasaki
Nutrition and Cancer 2021 ( 73 ) 889 - 898 2020.7
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DFT Supported Structural Revision of Seiricardines
Mami Nishiyama, Wilanfranco C. Tayone, Hayato Maeda, Kazuaki Tanaka, Masaru Hashimoto
Bulletin of the Chemical Society of Japan 93 ( 6 ) 768 - 775 2020.6
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Blackcurrant ( Ribes nigrum) Extract Prevents Dyslipidemia and Hepatic Steatosis in Ovariectomized Rats.
Naoki Nanashima, Kayo Horie, Kanako Yamanouchi, Toshiko Tomisawa, Maiko Kitajima, Indrawati Oey, Hayato Maeda
Nutrients 12 ( 5 ) E1541 - 1541 2020.5
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DFT supported structural elucidations of seiridiasteriscane A, unique 15-nor-asteriscane and novel pestalotiopsin Congeners from Seiridium sp. KT3957
Wilanfranco C. Tayone, Mami Nishiyama, Kazuaki Tanaka, Maeda Hayato, Masaru Enomoto, Masaru Hashimoto
Tetrahedron 76 ( 20 ) 131197 2020.5
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Condition-dependent adenosine monophosphate decomposition pathways in striated adductor muscle from Japanese scallop (Patinopecten yessoensis).
Huamao Wei, Yuanyong Tian, Yumeng Lin, Hayato Maeda, Tetsuro Yamashita, Kefeng Yu, Koichi Takaki, Chunhong Yuan
Journal of food science 85 ( 5 ) 1462 - 1469 2020.5
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High fucoxanthin wakame (Undaria pinnatifida) prevents tumor microenvironment formation in an AOM/DSS mouse carcinogenic model.
M Terasaki, Y Kuramitsu, M Kojoma, Sang-Yong Kim, T Tanaka, H Maeda, K Miyashita, C Kawagoe, S Kohno, M Mutoh
Journal of Functional Foods 64 103709 2020.1
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Dietary Fucoxanthin Induces Anoikis in Colorectal Adenocarcinoma by Suppressing Integrin Signaling in a Murine Colorectal Cancer Model.
Journal of clinical medicine 9 ( 1 ) 90 2019.12
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Effects of Blackcurrant Anthocyanin on Endothelial Function and Peripheral Temperature in Young Smokers.
T Tomisawa, N Nanashima, M Kitajima, K Mikami, S Takamagi, H Maeda, K Horie, F Lai, T Osanai
Molecules (Basel, Switzerland) 24 ( 23 ) E4295 - 4295 2019.11
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DFT calculation-assisted stereo-structural assignment of arundifungin.
M Nishiyama, A Tonouchi, H Maeda, M Hashimoto
Chirality 32 ( 1 ) 17 - 31 2019.11
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Neomacrophorin and premacrophorin congeners from Trichoderma sp. 1212-03
Mami Nishiyama, Hayato Maeda, Akio Tonouchi, Masaru Hashimoto
Tetrahedron 75 ( 22 ) 2993 - 3000 2019.5
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Structure-activity relationships of trichothecenes against COLO201 cells and Cochliobolus miyabeanus: The role of 12-epoxide and macrocyclic moieties.
Manami Matsumoto, Mami Nishiyama, Hayato Maeda, Akio Tonouchi, Katsuhiro Konno, Masaru Hashimoto
Bioorganic & medicinal chemistry letters 29 ( 8 ) 982 - 985 2019.4
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RNAi-Mediated Down-Regulation of Dicer-Like 2 and 4 Changes the Response of 'Moneymaker' Tomato to Potato Spindle Tuber Viroid Infection from Tolerance to Lethal Systemic Necrosis, Accompanied by Up-Regulation of miR398, 398a-3p and Production of Excessive Amount of Reactive Oxygen Species.
Takahiro Suzuki, Sho Ikeda, Atsushi Kasai, Akito Taneda, Misato Fujibayashi, Kohei Sugawara, Maki Okuta, Hayato Maeda, Teruo Sano
Viruses 11 ( 4 ) 344 2019.4
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Phytoestrogenic Effects of Blackcurrant Anthocyanins Increased Endothelial Nitric Oxide Synthase (eNOS) Expression in Human Endothelial Cells and Ovariectomized Rats.
Kayo Horie, Naoki Nanashima, Hayato Maeda
Molecules (Basel, Switzerland) 24 ( 7 ) E1259 2019.3
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Salivary Glycine Is a Significant Predictor for the Attenuation of Polyp and Tumor Microenvironment Formation by Fucoxanthin in AOM/DSS Mice.
Masaru Terasaki, Saki Masaka, Chinami Fukada, Mayu Houzaki, Tetsuya Endo, Takuji Tanaka, Hayato Maeda, Kazuo Miyashita, Michihiro Mutoh
In vivo (Athens, Greece) 33 ( 2 ) 365 - 374 2019.3
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Fucoxanthin administration delays occurrence of tumors in xenograft mice by colonospheres, with an anti-tumor predictor of glycine.
Masaru Terasaki, Naoya Matsumoto, Ryuichi Hashimoto, Tetsuya Endo, Hayato Maeda, Junichi Hamada, Kazumi Osada, Kazuo Miyashita, Michihiro Mutoh
Journal of clinical biochemistry and nutrition 64 ( 1 ) 52 - 58 2019.1
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Fucoxanthin potentiates anoikis in colon mucosa and prevents carcinogenesis in AOM/DSS model mice.
Masaru Terasaki, Tatsuya Iida, Fubuki Kikuchi, Kanae Tamura, Tetsuya Endo, Yasuhiro Kuramitsu, Takuji Tanaka, Hayato Maeda, Kazuo Miyashita, Michihiro Mutoh
The Journal of nutritional biochemistry 64 198 - 205 2018.10
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Effects of paprika xanthophyll on chronic inflammation in adipocyte
Maeda H, Mikami S, Hokari S, Nishino A, Takaha T, Maoka T.
Carotenoid Science 22 45 - 46 2018.9
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Anti-Oxidant and Fucoxanthin Contents of Brown Alga Ishimozuku (Sphaerotrichia divaricata) from the West Coast of Aomori, Japan.
Hayato Maeda, Satoru Fukuda, Hikari Izumi, Naotsune Saga
Marine drugs 16 ( 8 ) E255 - E255 2018.7
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Cyclohelminthols Y1-Y4 Metabolites Possessing Two Spirocyclopropanes in Their Structure.
Shizuya Tanaka, Kazuaki Tanaka, Hayato Maeda, Masaru Hashimoto
The Journal of organic chemistry 83 ( 10 ) 5688 - 5697 2018.5
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Occurrence and tolerance mechanisms of seed cracking under low temperatures in soybean (Glycine max).
Mineo Senda, Michio Kawasaki, Miho Hiraoka, Kazuki Yamashita, Hayato Maeda, Naoya Yamaguchi
Planta 248 ( 2 ) 369 - 379 2018.5
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Glycine and succinic acid are effective indicators of the suppression of epithelial-mesenchymal transition by fucoxanthinol in colorectal cancer stem-like cells.
Masaru Terasaki, Masatoshi Mima, Satoki Kudoh, Tetsuya Endo, Hayato Maeda, Junichi Hamada, Kazumi Osada, Kazuo Miyashita, Michihiro Mutoh
Oncology reports 40 ( 1 ) 414 - 424 2018.4
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Blackcurrant Anthocyanins Increase the Levels of Collagen, Elastin, and Hyaluronic Acid in Human Skin Fibroblasts and Ovariectomized Rats.
Naoki Nanashima, Kayo Horie, Hayato Maeda, Toshiko Tomisawa, Maiko Kitajima, Toshiya Nakamura
Nutrients 10 ( 4 ) E495 2018.4
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Glycine Is a Predictor for a Suppressive Effect of Fucoxanthinol on Colonosphere Formation Under Hypoxia.
Masaru Terasaki, Yuki Ogawa, Tetsuya Endo, Hayato Maeda, Junichi Hamada, Kazumi Osada, Kazuo Miyashita, Michihiro Mutoh
Anticancer research 38 ( 4 ) 2169 - 2179 2018.4
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Effects of level of fresh apple pomace in mixed silage on growth performance, meat quality and serum metabolites in finishing pigs
The Japanese journal of swine science 55 ( 1 ) 1 - 11 2018.3
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Single Oral Administration of Anthocyanin Rescues Smoking-Induced Endothelial Dysfunction in Young Smokers but Facilitates Oxidative Stress in Non-Smokers
Akane Yoshizaki, Toshiko Tomisawa, Tomohiro Osanai, Naoki Nanashima, Maiko Kitajima, Kasumi Mikami, Toshifumi Fujita, Hayato Maeda, Yoji Kato
Food and Nutrition Sciences 9 179 - 190 2018.3
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Phytoestrogenic Activity of Blackcurrant Anthocyanins Is Partially Mediated through Estrogen Receptor Beta.
Naoki Nanashima, Kayo Horie, Hayato Maeda
Molecules 23 ( 1 ) E74 2017.12
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Induction of Anoikis in Human Colorectal Cancer Cells by Fucoxanthinol.
Masaru Terasaki, Hayato Maeda, Kazuo Miyashita, Michihiro Mutoh
Nutrition and cancer 69 ( 7 ) 1043 - 1052 2017.10
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Anthocyanin-rich blackcurrant extract inhibits proliferation of the MCF10A healthy human breast epithelial cell line through induction of G0/G1 arrest and apoptosis.
Naoki Nanashima, Kayo Horie, Mitsuru Chiba, Manabu Nakano, Hayato Maeda, Toshiya Nakamura
Molecular medicine reports 16 ( 5 ) 6134 - 6141 2017.8
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Cyclohelminthol X, a Hexa-Substituted Spirocyclopropane from Helminthosporium velutinum yone96: Structural Elucidation, Electronic Circular Dichroism Analysis, and Biological Properties.
Shizuya Tanaka, Yuna Honmura, Shota Uesugi, Eri Fukushi, Kazuaki Tanaka, Hayato Maeda, Ken-Ichi Kimura, Tatsuo Nehira, Masaru Hashimoto
The Journal of organic chemistry 82 ( 11 ) 5574 - 5582 2017.6
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Differential Effects of Cod Proteins and Tuna Proteins on Serum and Liver Lipid Profiles in Rats Fed Non-Cholesterol- and Cholesterol-Containing Diets.
Ryota Hosomi, Hayato Maeda, Yuki Ikeda, Yuko Toda, Munehiro Yoshida, Kenji Fukunaga
Preventive nutrition and food science 22 ( 2 ) 90 - 99 2017.6
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Neomacrophorin X, a [4.4.3]Propellane-Type Meroterpenoid from Trichoderma sp 1212-03
Kazuaki Kusakabe, Yuna Honmura, Shota Uesugi, Akio Tonouchi, Hayato Maeda, Ken-ichi Kimura, Hiroyuki Koshino, Masaru Hashimoto
JOURNAL OF NATURAL PRODUCTS 80 ( 5 ) 1484 - 1492 2017.5
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A marine bio-functional lipid, fucoxanthinol, attenuates human colorectal cancer stem-like cell tumorigenicity and sphere formation
Masaru Terasaki, Hayato Maeda, Kazuo Miyashita, Takuji Tanaka, Shingo Miyamoto, Michihiro Mutoh
Journal of Clinical Biochemistry and Nutrition 61 ( 1 ) 25 - 31 2017.5
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Dietary Tuna Dark Muscle Protein Attenuates Hepatic Steatosis and Increases Serum High-Density Lipoprotein Cholesterol in Obese Type-2 Diabetic/Obese KK-Ay Mice.
Hayato Maeda, Ryota Hosomi, Mari Fukuda, Yuki Ikeda, Munehiro Yoshida, Kenji Fukunaga
Journal of food science 82 ( 5 ) 1231 - 1238 2017.5
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Accumulation of proanthocyanidins and/or lignin deposition in buff-pigmented soybean seed coats may lead to frequent defective cracking.
M Senda, N Yamaguchi, M Hiraoka, S Kawada, R Iiyoshi, K Yamashita, T Sonoki, H Maeda, M Kawasaki
Planta 245 ( 3 ) 659 - 670 2017.3
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EPR imaging and HPLC characterization of the pigment-based organic free radical in black soybean seeds.
Kouichi Nakagawa, Hayato Maeda
FREE RADICAL RESEARCH 51 ( 2 ) 187 - 192 2017.2
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Investigating Pigment Radicals in Black Rice Using HPLC and Multi-EPR.
Kouichi Nakagawa, Hayato Maeda
Journal of oleo science 66 ( 5 ) 543 - 547 2017.1
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Apple breeding programs at Hirosaki University, Japan:yellow skin, red flesh, and large size
Matsumoto K, Maeda H, Fujita T, Sato S, Shiozaki Y.
ISHS Acta Horticulturae 1127 29 - 33 2016.11
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Homopetasinic acid isolated from Diaporthe sp. strain 1308-05
Atsushi Ito, Ikuya Kumagai, Miku Maruyama, Hayato Maeda, Akio Tonouchi, Tatsuo Nehira, Ken-ichi Kimura, Masaru Hashimoto
Tetrahedron Letters 57 ( 10 ) 1117 - 1119 2016.3
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Homojesterones: vinylogous analogues of jesterone from Helminthosporium velutinum TS28
Miki Arayama, Shota Uesugi, Kazuaki Tanaka, Hayato Maeda, Tatsuo Nehira, Ken-ichi Kimura, Masaru Hashimoto
Tetrahedron 72 ( 7 ) 1031 - 1035 2016.2
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Isolation, absolute structures, and biological properties of cyclohelminthols I-IV from Helminthosporium velutinum yone96
Yuna Honmura, Shota Uesugi, Hayato Maeda, Kazuaki Tanaka, Tatsuo Nehira, Ken-ichi Kimura, Masaaki Okazaki, Masaru Hashimoto
Tetrahedron 72 ( 10 ) 1400 - 1405 2016.1
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Achaetolide-II isolated from Helminthosporium velutinum TS28
Miki Arayama, Hayato Maeda, Kazuaki Tanaka, Noboru Takada, Tatsuo Nehira, Masaru Hashimoto
Tetrahedron 71 ( 41 ) 7900 - 7905 2015.10
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Phytoestrogenic activity of blackcurrant (Ribes nigrum) anthocyanins is mediated through estrogen receptor alpha
Naoki Nanashima, Kayo Horie, Toshiko Tomisawa, Mitsuru Chiba, Manabu Nakano, Toshifumi Fujita, Hayato Maeda, Maiko Kitajima, Shizuka Takamagi, Daishi Uchiyama, Jun Watanabe, Toshiya Nakamura, Yoji Kato
Molecular nutrition & food research 59 ( 12 ) 2419 - 2431 2015.9
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Fucoxanthinol, Metabolite of Fucoxanthin, Improves Obesity-Induced Inflammation in Adipocyte Cells
Hayato Maeda, Shogo Kanno, Mei Kodate, Masashi Hosokawa, Kazuo Miyashita
Marine drugs 13 ( 8 ) 4799 - 4813 2015.8
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Isolation, ECD assisted structural analyses, biosynthetic discussions, and biological activities of epi-cochlioquinones D and its derivatives
Arayama M, Nehira T, Maeda H, Tanaka K, Miyagawa H, Ueno T, Hosokawa S, Hashimoto M
Tetrahedron 71 ( 29 ) 4788 - 4794 2015.7
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Relative and absolute structure of phomolide C
Atsushi Ito, Hyato Maeda, Akio Tonouchi, Masaru Hashimoto
Biosci Biotechnol Biochem. 79 ( 7 ) 1067 - 1069 2015.7
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Computation-Assisted Structural Elucidation of Epoxyroussoeone and Epoxyroussoedione Isolated from Roussoella japanensis KT1651
Yuna Honmura, Hiroto Takekawa, Kazuaki Tanaka, Hayato Maeda, Tatsuo Nehira, Warren Hehre, Masaru Hashimoto
JOURNAL OF NATURAL PRODUCTS 78 ( 7 ) 1505 - 1510 2015.6
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Effect of Calcium Concentration in Growth Medium on Oxalate Content and Evaluation of the Role of Guttation in the Regulation of Oxalate in Eddo
Mohammad Nazrul Islam, Hayato Maeda, Michio Kawasaki
Plant Production Science 18 ( 4 ) 464 - 470 2015.5
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Isolation of stress tolerant microalgae in Aomori area: its morphological and physiological characteristics Ⅰ.
SHIRAKAMI KENKYU ( 10 ) 3 - 10 2015.3
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Nutraceutical effects of fucoxanthin for obesity and diabetes therapy: A Review
Journal of Oleo Science 64 ( 2 ) 125 - 132 2015.1
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Dietary cod protein decreases triacylglycerol accumulation and fatty acid desaturase indices in the liver of obese type-2 diabetic KK-Ay mice
Maeda H, Hosomi R, Koizumi M, Toda Y, Mitsui M, Fukunaga K.
Journal of Functional Foods 14 87 - 94 2015.1
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Neomacrophorin I, II, and III, novel drimenyl cyclohexanes with hydroxylated butanoates from Trichoderma sp. 1212-03
Tetrahedron 70 ( 7 ) 1458 - 1463 2014.2
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Chemical Composition of Salmon Ovary Outer Membrane and Its Protein Increases Fecal Mucins Content in C57BL/6J and Type 2 Diabetic/Obese KK-Ay Mice
Maeda H, Hosomi R, Chiba U, Fukunaga K
Foods 2 ( 3 ) 415 - 429 2013.9
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Paprika Pigments Attenuate Obesity-Induced Inflammation in 3T3-L1 Adipocytes
Maeda H, Saito S, Nakamura N, Maoka T
ISRN Inflammation 2013 ( 763758 ) 9 2013.3
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Kuromoji (Lindera umbellata) Essential Oil Inhibits LPS-Induced Inflammation in RAW 264.7 Cells.
Maeda H, Yamazaki M, Katagaya Y
Bioscience, biotechnology, and biochemistry 77 ( 3 ) 482 - 486 2013.3
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Fucoxanthin as potential nutraceutical for obesity therapy : A Review
Miyashita K, Maeda H, Nishikawa S, Tsukui T, TWidjaja-Adhi M A, Hosokawa H
Carotenoid Science 17 1 - 7 2012.12
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Combined antiproliferative effect of dietary PPARγ suppressing lipids fucoxanthinol and 1,25-dihydroxyvitamin D3 in human colon cancer cells.
Teraski M, Nagao A, Maeda H, Miyashita K, Masuda S
Carotenoid Science 17 40 - 43 2012.12
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Neoxanthin in Komatsuna improves lipid metabolism in adipocyte cells
Maeda H, Abe M, Hosokawa M, Miyashita K, Katagata Y.
Carotenoid Science 17 51 - 52 2012.12
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Kuromoji (Lindera umbellata) essential oil-induced apoptosis and differentiation in human leukemia HL-60 cells
Maeda H, Yamazaki M, Katagata Y.
EXPERIMENTAL AND THERAPEUTIC MEDICINE 3 49 - 52 2012.1
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Anti-obesity and anti-diabetic effects of allenic carotenoid, fucoxanthin
Miyashit K , Maeda H , Okada T, Abe M, Hosokawa M
agro Food industry hi-tech 21 ( 6 ) 24 - 27 2010.12
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Anti-obesity and anti-diabetic effects of fucoxanthin on diet induced obesity conditions in murine model.
Maeda H, Hosokawa M, Sashima T, Murakami-Funayama K, Miyashita K.
Molecular Medicine Reports 2 897 - 902 2009.11
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Suppressive Effect of Neoxanthin on the Differentiation of 3T3-L1 Adipose Cells
Tomoko Okada, Miho Nakai, Hayato Maeda, Masashi Hosokawa, Tokutake Sashima, Kazuo Miyashita
JOURNAL OF OLEO SCIENCE 57 ( 6 ) 345 - 351 2008.6
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フコキサンチンの抗肥満効果に関する研究
前多隼人
博士論文 （北海道大学）甲第8690号 2008.3
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Seaweed carotenoid, fucoxanthin, as a multi-functional nutrient
Maeda H, Tsukui T, Sashima T, Hosokawa M, Miyashita K
Asia Pacific journal of clinical nutrition 17 ( S1 ) 196 - 199 2008.1
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Effect of medium-chain triacylglycerols on anti-obesity effect of fucoxanthin.
Maeda H, Hosokawa M, Sashima T, Funayama K, Miyashita K
Journal of oleo science 56 ( 12 ) 615 - 621 2007.12
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Radical scavenging and singlet oxygen quenching activity of marine carotenoid fucoxanthin and its metabolites.
Sachindra NM, Sato E, Maeda H, Hosokawa M, Niwano Y, Kohno M, Miyashita K
Journal of agricultural and food chemistry 55 ( 21 ) 8516 - 8522 2007.10
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Dietary combination of fucoxanthin and fish oil attenuates the weight gain of white adipose tissue and decreases blood glucose in obese/diabetic KK-Ay mice.
Maeda H, Hosokawa M, Sashima T, Miyashita K
Journal of agricultural and food chemistry 55 ( 19 ) 7701 - 7706 2007.9
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Effect of medium-chain triacylglycerols on anti-obesity effect of fucoxanthin.
Maeda H, Hosokawa M, Sashima T, Funayama K, Miyashita K
Journal of oleo science 56 ( 12 ) 615 - 621 2007.8
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Fucoxanthin and fucoxanthinol enhance the amount of docosahexaenoic acid in the liver of KKAy obese/diabetic mice.
Tsukui T, Konno K, Hosokawa M, Maeda H, Sashima T, Miyashita K
Journal of agricultural and food chemistry 55 ( 13 ) 5025 - 5029 2007.6
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Fucoxanthin and its metabolite, fucoxanthinol, suppress adipocyte differentiation in 3T3-L1 cells.
Maeda H, Hosokawa M, Sashima T, Takahashi N, Kawada T, Miyashita K
International journal of molecular medicine 18 ( 1 ) 147 - 152 2006.7
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Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues.
Maeda H, Hosokawa M, Sashima T, Funayama K, Miyashita K
Biochemical and biophysical research communications 332 ( 2 ) 392 - 397 2005.7
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Fucoxanthin induces apoptosis and enhances the antiproliferative effect of the PPARg ligand, troglitazone, on colon cancer cells.
Hosokawa M, Kudo M, Maeda H, Kohno H, Tanaka T, Miyashita K
Biochimica et biophysica acta 1675 ( 1-3 ) 113 - 119 2004.11