論文 - 坂元 君年
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Design syntheses and mitochondrial complex I inhibitory activity of novel acetogenin mimics
K Kuwabara, M Takada, J Iwata, K Tatsumoto, K Sakamoto, H Iwamura, H Miyoshi
EUROPEAN JOURNAL OF BIOCHEMISTRY 267 ( 9 ) 2538 - 2546 2000年05月
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Defining the structural domain of subunit II of the heme-copper terminal oxidase using chimeric enzymes constructed from the Escherichia coli bo-type ubiquinol oxidase and the thermophilic Bacillus caa(3)-type cytochrome c oxidase
K Sakamoto, T Mogi, S Noguchi, N Sone
JOURNAL OF BIOCHEMISTRY 126 ( 5 ) 934 - 939 1999年11月
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Characterization of the ubiquinol oxidation sites in cytochromes bo and bd from Escherichia coli using aurachin C analogues
H Miyoshi, K Takegami, K Sakamoto, T Mogi, H Iwamura
JOURNAL OF BIOCHEMISTRY 125 ( 1 ) 138 - 142 1999年01月
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The quinohemoprotein alcohol dehydrogenase of Gluconobacter suboxydans has ubiquinol oxidation activity at a site different from the ubiquinone reduction site
K Matsushita, T Yakushi, H Toyama, O Adachi, H Miyoshi, E Tagami, K Sakamoto
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1409 ( 3 ) 154 - 164 1999年01月
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Role of the isoprenyl tail of ubiquinone in reaction with respiratory enzymes: Studies with bovine heart mitochondrial complex I and Escherichia coli bo-type ubiquinol oxidase
K Sakamoto, H Miyoshi, M Ohshima, K Kuwabara, K Kano, T Akagi, T Mogi, H Iwamura
BIOCHEMISTRY 37 ( 43 ) 15106 - 15113 1998年10月
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Isolation and characterizations of quinone analogue-resistant mutants of bo-type ubiquinol oxidase from Escherichia coli
M Sato-Watanabe, T Mogi, K Sakamoto, H Miyoshi, Y Anraku
BIOCHEMISTRY 37 ( 37 ) 12744 - 12752 1998年09月
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Specificity of pyridinium inhibitors of the ubiquinone reduction sites in mitochondrial complex I
H Miyoshi, J Iwata, K Sakamoto, H Furukawa, M Takada, H Iwamura, T Watanabe, Y Kodama
JOURNAL OF BIOLOGICAL CHEMISTRY 273 ( 28 ) 17368 - 17374 1998年07月
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Characterization of the ubiquinone reduction site of mitochondrial complex I using bulky synthetic ubiquinones
M Ohshima, H Miyoshi, K Sakamoto, K Takegami, J Iwata, K Kuwabara, H Iwamura, T Yagi
BIOCHEMISTRY 37 ( 18 ) 6436 - 6445 1998年05月
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Probing the ubiquinone reduction site of mitochondrial complex I using novel cationic inhibitors
H Miyoshi, M Inoue, S Okamoto, M Ohshima, K Sakamoto, H Iwamura
JOURNAL OF BIOLOGICAL CHEMISTRY 272 ( 26 ) 16176 - 16183 1997年06月
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Probing substrate binding site of the Escherichia coli quinol oxidases using synthetic ubiquinol analogues
K Sakamoto, H Miyoshi, K Takegami, T Mogi, Y Anraku, H Iwamura
JOURNAL OF BIOLOGICAL CHEMISTRY 271 ( 47 ) 29897 - 29902 1996年11月
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Comparison of the inhibitory action of synthetic capsaicin analogues with various NADH-ubiquinone oxidoreductases
T Satoh, H Miyoshi, K Sakamoto, H Iwamura
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1273 ( 1 ) 21 - 30 1996年01月
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Comparison of the structural features of ubiquinone reduction sites between glucose dehydrogenase in Escherichia coli and bovine heart mitochondrial complex I
Kimitoshi Sakamoto, Hideto Miyoshi, Kazunobu Matsushita, Masato Nakagawa, Junko Ikeda, Michiyo Ohshima, Osao Adachi, Toshio Akagi, Hajime Iwamura
European Journal of Biochemistry 237 ( 1 ) 128 - 135 1996年