論文 - 花田 賢二
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Overexpression of coupling factor 6 attenuates exercise-induced physiological cardiac hypertrophy by inhibiting PI3K/Akt signaling in mice
Sagara Shigeki, Osanai Tomohiro, Itoh Taihei, Izumiyama Kei, Shibutani Shuji, Hanada Kenji, Yokoyama Hiroaki, Yamamoto Yuko, Yokota Takashi, Tomita Hirofumi, Magota Koji, Okumura Ken
JOURNAL OF HYPERTENSION 30 ( 4 ) 778 - 786 2012年04月
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Coronary vasospasm induced in transgenic mouse with increased phospholipase C-δ1 activity.
Shuji Shibutani, Tomohiro Osanai, Toshihiro Ashitate, Shigeki Sagara, Kei Izumiyama, Yuko Yamamoto, Kenji Hanada, Takashi Echizen, Hirofumi Tomita, Takeshi Fujita, Takeshi Miwa, Hiroaki Matsubara, Yoshimi Homma, Ken Okumura
Circulation 125 ( 8 ) 1027 - 1036 2012年02月
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Coronary Vasospasm Induced in Transgenic Mouse With Increased Phospholipase C-delta 1 Activity
Shibutani Shuji, Osanai Tomohiro, Ashitate Toshihiro, Sagara Shigeki, Izumiyama Kei, Yamamoto Yuko, Hanada Kenji, Echizen Takashi, Tomita Hirofumi, Fujita Takeshi, Miwa Takeshi, Matsubara Hiroaki, Homma Yoshimi, Okumura Ken
CIRCULATION 125 ( 8 ) 1027 - 1036 2012年02月
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Randomized study on the efficacy and safety of landiolol, an ultra-short-acting β1-adrenergic blocker, in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention
Hanada Kenji, Higuma Takumi, Nishizaki Fumie, Sukekawa Takanori, Yokota Takashi, Yamada Masahiro, Saito Shin, Kushibiki Motoi, Oikawa Koichi, Abe Naoki, Tomita Hirofumi, Osanai Tomohiro, Okumura Ken
日本循環器學誌 76 ( 2 ) 439 - 445 2012年
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Overexpression of Coupling Factor 6 Attenuates Exercise-Induced Physiological Cardiac Hypertrophy By Inhibiting Pi3k/akt Signaling in Mice
Sagara Shigeki, Osanai Tomihiro, Suzuki Akiko, Nishizaki Fumie, Sukekawa Takanori, Itoh Taihei, Izumiyama Kei, Shibutani Shuji, Hanada Kenji, Yamamoto Yuko, Yokoyama Hiroaki, Yokota Takashi, Tomita Hirofumi, Okumura Ken
CIRCULATION 124 ( 21 ) 2011年11月
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Inhibition of P38 MAP Kinase Attenuates Left Ventricular Hypertrophy and Inhibits Progression of Systolic Dysfunction on Pressure-Overload Induced Pathological Cardiac Hypertrophy in Mice
Hanada Kenji, Osanai Tomohiro, Sukekawa Takanori, Ohya Fumie, Izumiyama Kei, Sagara Shigeki, Ito Taihei, Yamamoto Yuko, Shibutani Shuji, Tomita Hirofumi, Okumura Ken
弘前醫學 62 ( 1 ) 18 - 26 2011年04月
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Mutation Analysis ABCC9 Gene in Japanese Patients with Coronary Spastic Angina
Shibutani Shuji, Osanai Tomohiro, Oya Humie, Sagara Shigeki, Izumiyama Kei, Yamamoto Yuko, Hanada Kenji, Tomita Hirofumi, Okumura Ken
弘前醫學 62 ( 1 ) 27 - 33 2011年04月
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p38 MAP kinase の抑制はマウスの圧負荷による病的心肥大を軽減し心機能低下を抑制する
花田 賢二, 長内 智宏, 祐川 誉徳, 大矢 史恵, 泉山 圭, 相樂 繁樹, 伊藤 太平, 山本 祐子, 渋谷 修司, 富田 泰史, 奥村 謙
弘前医学 62 ( 1 ) 18 - 26 2011年
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日本人冠攣縮性狭心症患者における ABCC9遺伝子変異の有無の解析
渋谷 修司, 長内 智宏, 大矢 史恵, 相樂 繁樹, 泉山 圭, 山本 祐子, 花田 賢二, 富田 泰史, 奥村 謙
弘前医学 62 ( 1 ) 27 - 33 2011年
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Overexpression of Coupling Factor 6 Attenuates Physiological Cardiac Hypertrophy Induced by Swimming and Causes Systolic Cardiac Dysfunction in Mice
Sagara Shigeki, Osanai Tomohiro, Itoh Taihei, Izumiyama Kei, Shibutani Shuji, Hanada Kenji, Yamamoto Yuko, Okumura Ken
CIRCULATION 122 ( 21 ) 2010年11月
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Overexpression of Coupling Factor 6 Causes Salt-Sensitive Hypertension and Systolic Cardiac Dysfunction: Gender as an Important Modulator
Izumiyama Kei, Osanai Tomohiro, Ashitate Toshihiro, Sagara Shigeki, Itoh Taihei, Shibutani Shuji, Hanada Kenji, Yamamoto Yuko, Okumura Ken
CIRCULATION 122 ( 21 ) 2010年11月
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Overexpression of coupling factor 6 causes cardiac dysfunction under high-salt diet in mice.
Toshihiro Ashitate, Tomohiro Osanai, Makoto Tanaka, Koji Magota, Takashi Echizen, Kei Izumiyama, Hiroaki Yokoyama, Shuji Shibutani, Kenji Hanada, Hirofumi Tomita, Ken Okumura
Journal of hypertension 28 ( 11 ) 2243 - 2251 2010年11月
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Effects of telmisartan on markers of ventricular remodeling in patients with acute myocardial infarction: comparison with enalapril.
Takashi Yokota, Tomohiro Osanai, Kenji Hanada, Motoi Kushibiki, Naoki Abe, Koichi Oikawa, Hirofumi Tomita, Takumi Higuma, Jin Yokoyama, Hiroyuki Hanada, Ken Okumura
Heart and vessels 25 ( 6 ) 460 - 468 2010年11月
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Effects of telmisartan on markers of ventricular remodeling in patients with acute myocardial infarction: comparison with enalapril
Yokota Takashi, Osanai Tomohiro, Hanada Kenji, Kushibiki Motoi, Abe Naoki, Oikawa Koichi, Tomita Hirofumi, Higuma Takumi, Yokoyama Jin, Hanada Hiroyuki, Okumura Ken
HEART AND VESSELS 25 ( 6 ) 460 - 468 2010年11月
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Overexpression of coupling factor 6 causes cardiac dysfunction under high-salt diet in mice
Ashitate Toshihiro, Osanai Tomohiro, Tanaka Makoto, Magota Koji, Echizen Takashi, Izumiyama Kei, Yokoyama Hiroaki, Shibutani Shuji, Hanada Kenji, Tomita Hirofumi, Okumura Ken
JOURNAL OF HYPERTENSION 28 ( 11 ) 2243 - 2251 2010年11月
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OE-070 Plasma Soluble Lectin-like Oxidized Low-density Lipoprotein Receptor-1 Level at Admission can Predict In-hospital Prognosis in Patients with Acute Myocardial Infarction(OE12,ACS/AMI (Clinical/Pathophysiology) (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
Higuma Takumi, Hanada Kenji, Abe Naoki, Oikawa Koichi, Kushibiki Motoi, Yokota Takashi, Yamamoto Yuko, Ohya Fumie, Hanada Hiroyuki, Osanai Tomohiro, Kume Noriaki, Okumura Ken
Circulation journal : official journal of the Japanese Circulation Society 73 ( 0 ) 191 2009年03月
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OJ-186 Efficacy and Safety of Landiolol, an Ultra Short-acting, β 1-selective Adrenergic Blocker, in Patients with Acute Myocardial Infarction Undergoing PCI(OJ31,ACS/AMI (Clinical/Treatment) (IHD),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
Hanada Kenji, Abe Naoki, Ohya Fumie, Sekiguchi Yuko, Yokota Takashi, Kushibiki Motoi, Oikawa Koichi, Higuma Takumi, Hanada Hiroyuki, Osanai Tomohiro, Okumura Ken
Circulation journal : official journal of the Japanese Circulation Society 73 ( 0 ) 332 - 333 2009年03月
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アミオダロンのマトリックスメタロプロテイナーゼ-2 活性に対する作用：ラット心筋梗塞モデルでの検討
堀内 大輔, 長内 智宏, 越前 崇, 芦立 俊宗, 加藤 千里, 横山 公章, 花田 賢二, 澁谷 修司, 伊藤 太平, 奥村 謙
弘前医学 60 ( 1-4 ) 45 - 53 2009年
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低酸素による心筋細胞 Insulin-like growth factor-1 遺伝子発現亢進の役割：心保護作用の機序について
加藤 千里, 長内 智宏, 渋谷 修司, 花田 賢二, 奥村 謙
弘前医学 60 ( 1-4 ) 36 - 44 2009年
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20)高度房室ブロックならびに流出路圧較差を生じたたこつぼ型心筋障害の一例(第144回日本循環器学会東北地方会)
相楽 繁樹, 樋熊 拓未, 花田 賢二, 澁谷 修司, 横田 貴志, 藤原 崇之, 阿部 直樹, 及川 広一, 富田 泰史, 木村 正臣, 佐々木 真吾, 横山 仁, 花田 裕之, 長内 智宏, 奥村 謙
71 ( 0 ) 984 2007年10月