Affiliation
Graduate School of Medicine Medical Science Course F
HIRAGA Hiroto
Degree
-
医学博士（細菌学）
Education
-
Hirosaki University 大学院（専攻：細菌学）
2003.04 ～ 2007.03
Country： Japan
-
Hirosaki University 医学部 医学科
1995.04 ～ 2001.03
Country： Japan
Campus Career
-
Hirosaki University Graduate School of Medicine Medical Science Course F Associate Professor
2022.08 ～ Now
-
Hirosaki University University Hospital Gastroenterology,Hematology and Rheumatology Lecturer
2020.04 ～ 202207
-
Hirosaki University Graduate School of Medicine Endowed Course Community Healthcare Department in Oodate and North-Akita Assistant Professor
2016.04 ～ 202003
Papers
-
Anti-integrin αvβ6 antibody as a biomarker for diagnosing ulcerative colitis: a nationwide multicenter validation study.
Okabe M, Yamamoto S, Shiokawa M, Hisamatsu T, Yamazaki H, Nakanishi R, Hamada K, Kitamoto H, Kuwada T, Uza N, Sakatani A, Fujii T, Ohno M, Matsuura M, Shibuya T, Ohmiya N, Ooi M, Hoshi N, Moriya K, Tsuchiya K, Yamaguchi Y, Kunisaki R, Takahara M, Takagi T, Takehara T, Hirai F, Kakimoto K, Esaki M, Nakase H, Kinjo F, Torisu T, Kanmura S, Narimatsu K, Matsuoka K, Hiraga H, Yokoyama K, Honzawa Y, Naganuma M, Saruta M, Kodama Y, Chiba T, Seno H
Journal of gastroenterology 60 ( 1 ) 86 - 95 2025.1
-
Publisher Correction: Anti-integrin αvβ6 antibody as a biomarker for diagnosing ulcerative colitis: a nationwide multicenter validation study.
Okabe M, Yamamoto S, Shiokawa M, Hisamatsu T, Yamazaki H, Nakanishi R, Hamada K, Kitamoto H, Kuwada T, Uza N, Sakatani A, Fujii T, Ohno M, Matsuura M, Shibuya T, Ohmiya N, Ooi M, Hoshi N, Moriya K, Tsuchiya K, Yamaguchi Y, Kunisaki R, Takahara M, Takagi T, Takehara T, Hirai F, Kakimoto K, Esaki M, Nakase H, Kinjo F, Torisu T, Kanmura S, Narimatsu K, Matsuoka K, Hiraga H, Yokoyama K, Honzawa Y, Naganuma M, Saruta M, Kodama Y, Chiba T, Seno H
Journal of gastroenterology 60 ( 2 ) 263 - 264 2024.12
-
Nationwide multicenter prospective study on the usefulness, safety, and acceptability of colon capsule endoscopy in Japan.
Hotta N, Ohmiya N, Hiraga H, Nakaji K, Osawa S, Omori T, Mitsufuji S, Hosoe N, Nouda S, Kobayashi T, Nakamura M, Oka S, Nonogaki K, Baba Y, Mukai R, Matsumoto H, Ikebuchi Y, Shimada M, Togashi K, Katsuki S, Sasaki Y, Sawada R, Kawano S, Furuta T, Tajiri H, Tanaka S, ColoCam-J Study Group
Gastrointestinal endoscopy 2024.11
-
A Logistic Regression Model for Predicting the Risk of Subsequent Surgery among Patients with Newly Diagnosed Crohn's Disease Using a Brute Force Method.
Ogasawara K, Hiraga H, Sasaki Y, Hiraga N, Higuchi N, Hasui K, Ota S, Maeda T, Murai Y, Tatsuta T, Kikuchi H, Chinda D, Mikami T, Matsuzaka M, Sakuraba H, Fukuda S
Diagnostics (Basel, Switzerland) 13 ( 23 ) 2023.12
-
Multicenter prospective registration study of efficacy and safety of capsule endoscopy in Crohn's disease in Japan (SPREAD-J study).
Toshiyuki Sakurai, Teppei Omori, Hiroki Tanaka, Takahiro Ito, Katsuyoshi Ando, Takeshi Yamamura, Sohachi Nanjjo, Satoshi Osawa, Teruyuki Takeda, Kenji Watanabe, Hiroto Hiraga, Shuji Yamamoto, Keiji Ozeki, Shinji Tanaka, Hisao Tajiri, Masayuki Saruta
Journal of gastroenterology 58 ( 10 ) 1003 - 1014 2023.7
-
Vitamin A Promotes the Fusion of Autophagolysosomes and Prevents Excessive Inflammasome Activation in Dextran Sulfate Sodium-Induced Colitis.
Hiroto Hiraga, Daisuke Chinda, Takato Maeda, Yasuhisa Murai, Kohei Ogasawara, Ryutaro Muramoto, Shinji Ota, Keisuke Hasui, Hirotake Sakuraba, Yoh Ishiguro, Shukuko Yoshida, Krisana Asano, Akio Nakane, Shinsaku Fukuda
International journal of molecular sciences 24 ( 10 ) 2023.5
-
Evaluation of Crohn's Disease Small-Bowel Mucosal Healing Using Capsule Endoscopy and Usefulness of Leucine-Rich α2-Glycoprotein.
Hiroto Hiraga, Daisuke Chinda, Keisuke Hasui, Yasuhisa Murai, Takato Maeda, Naoki Higuchi, Kohei Ogasawara, Sae Kudo, Yohei Sawada, Tetsuya Tatsuta, Hidezumi Kikuchi, Mami Ebina, Noriko Hiraga, Tatsuya Mikami, Hirotake Sakuraba, Shinsaku Fukuda
Diagnostics (Basel, Switzerland) 13 ( 4 ) 2023.2
-
特集 大腸の炎症を内視鏡で診る [IBD以外の大腸の炎症性疾患の内視鏡診療] 薬剤起因性腸炎
菊池 英純, 櫻庭 裕丈, 明本 由衣, 野宮 洋樹, 松岡 祐介, 相馬 郷, 太田 真二, 蓮井 桂介, 平賀 寛人
消化器内視鏡 36 ( 11 ) 1545 - 1548 2024.11
-
特集 炎症性腸疾患update [Chapter 1] IBDの病態・診断・病勢評価のupdate IBDとはどのような病気か
櫻庭 裕丈, 平賀 寛人, 菊池 英純, 蓮井 桂介, 太田 真二
内科 134 ( 5 ) 988 - 991 2024.11
-
‹一般演題抄録›潰瘍性大腸炎の難治化における Schlafen11発現の臨床的意義
村井 康久, 櫻庭 裕丈, 平賀 寛人, 蓮井 桂介, 太田 真二, 菊池 英純, 澤田 洋平, 立田 哲也, 川口 章吾, 明本 由衣, 珍田 大輔, 三上 達也, 黒瀬 顕, 福田 眞作
弘前医学 75 ( 1 ) 79 2024.10
-
増大号 炎症性腸疾患2024 主題 炎症性腸疾患の長期経過 潰瘍性大腸炎の長期予後
蓮井 桂介, 平賀 寛人, 太田 真二, 浅利 享, 澤田 洋平, 立田 哲也, 川口 章吾, 菊池 英純, 珍田 大輔, 明本 由衣, 坂本 義之, 袴田 健一, 福田 眞作, 櫻庭 裕丈
胃と腸 59 ( 10 ) 1521 - 1530 2024.10
-
Toll-Like Receptor 7-Expressed Macrophages Are Involved in the Pathogenesis of Esophageal Achalasia and Esophagogastric Junction Outflow Obstruction.
Kaizuka M, Tatsuta T, Kawaguchi S, Yoshizawa T, Yoshida S, Tateda T, Sawada Y, Ota S, Hayamizu S, Hasui K, Kikuchi H, Hiraga H, Chinda D, Muroya T, Hakamada K, Kijima H, Mikami T, Fukuda S, Sakuraba H
Digestion 105 ( 6 ) 1 - 12 2024.8
-
The new 222-nm far ultraviolet-C lowers bacterial contamination to endoscopists during esophagogastroduodenoscopy.
Fukutoku Y, Kikuchi H, Hoshi K, Narita K, Asari T, Miyazawa K, Sawada Y, Hayamizu S, Tatsuta T, Oota S, Hasui K, Hiraga H, Chinda D, Mikami T, Subsomwong P, Asano K, Yamane K, Ogawa Y, Sasaki M, Koi T, Ohashi H, Nakane A, Sakuraba H
DEN open 4 ( 1 ) e292 2024.4
-
‹一般演題抄録›当科の潰瘍性大腸炎の5-アミノサリチル酸製剤の不耐症例の特徴について
蓮井 桂介, 平賀 寛人, 小笠原 公平, 福德 友香理, 村井 康久, 澤田 洋平, 太田 真二, 速水 史郎, 立田 哲也, 菊池 英純, 珍田 大輔, 明本 由衣, 福田 眞作, 櫻庭 裕丈
弘前医学 74 ( 1-4 ) 142 2024.3
-
例会講座「大腸カプセル内視鏡を用いた全腸観察の有用性～TOTALStudy を中心に～」
平賀 寛人
弘前医学 74 ( 1-4 ) 139 - 140 2024.3
-
Heat-killed <i>Lactococcus lactis</i> subsp. <i>lactis</i> L8 ameliorates dextran sulfate sodium-induced colitis in mice
Kawaguchi Shogo, Chinda Daisuke, Ota Shinji, Tonouchi Akio, Maeda Hayato, Miura Kazuhide, Soma Go, Hiraga Hiroto, Ueno Kayo, Niioka Takenori, Tachizaki Mayuki, Seya Kazuhiko, Imaizumi Tadaatsu, Fukuda Shinsaku, Sakuraba Hirotake
Journal of Clinical Biochemistry and Nutrition advpub ( 0 ) 2024
-
Bacterial exposure risk to the endoscopist's face while performing endoscopy.
Kentaro Hoshi, Hidezumi Kikuchi, Koji Narita, Yukari Fukutoku, Taka Asari, Kuniaki Miyazawa, Yasuhisa Murai, Yohei Sawada, Tetsuya Tatsuta, Keisuke Hasui, Hiroto Hiraga, Daisuke Chinda, Tatsuya Mikami, Phawinee Subsomwong, Krisana Asano, Akio Nakane, Shinsaku Fukuda, Hirotake Sakuraba
DEN open 3 ( 1 ) e209 2023.4
-
Polygonum tinctorium leaf extract ameliorates high-fat diet-induced intestinal epithelial damage in mice.
Shogo Kawaguchi, Hirotake Sakuraba, Hidezumi Kikuchi, Kota Matsuki, Yudai Hayashi, Jiangli Ding, Yusuke Tanaka, Kazuhiko Seya, Tomoh Matsumiya, Hiroto Hiraga, Shinsaku Fukuda, Kenroh Sasaki, Tadaatsu Imaizumi
Experimental and therapeutic medicine 25 ( 3 ) 112 - 112 2023.3
-
Evaluation of Crohn's Disease Small-Bowel Mucosal Healing Using Capsule Endoscopy and Usefulness of Leucine-Rich α2-Glycoprotein.
Hiraga H, Chinda D, Hasui K, Murai Y, Maeda T, Higuchi N, Ogasawara K, Kudo S, Sawada Y, Tatsuta T, Kikuchi H, Ebina M, Hiraga N, Mikami T, Sakuraba H, Fukuda S.
Diagnostics (Basel). 2023.2
-
Polygonum tinctorium leaves suppress sodium dextran sulfate-induced colitis through interleukin-10-related pathway.
Asari T, Kikuchi H, Kawaguchi S, Sakuraba H, Yoshida S, Akemoto Y, Maeda T, Ota S, Murai Y, Higuchi N, Hoshi K, Fukutoku Y, Hiraga H, Sasaki K, Fukuda S.
Biochemistry and Biophysics Reports. 2022.7
-
Tacrolimus Up-regulates Expression of TGFβ Receptor Type II via ERK, Providing Protection Against Intestinal Epithelial Injury.
Satake M, Sakuraba H, Hiraga H, Yoshida S, Akemoto Y, Ota S, Murai Y, Hasui K, Kawaguchi S, Kikuchi H, Fukuda S.
In Vivo. 2022.7
-
Polygonum tinctorium leaves suppress sodium dextran sulfate-induced colitis through interleukin-10-related pathway.
Taka Asari, Hidezumi Kikuchi, Shogo Kawaguchi, Hirotake Sakuraba, Shukuko Yoshida, Yui Akemoto, Takato Maeda, Ota Shinji, Yasuhisa Murai, Naoki Higuchi, Kentaro Hoshi, Yukari Fukutoku, Hiroto Hiraga, Kenroh Sasaki, Shinsaku Fukuda
Biochemistry and biophysics reports 30 101272 - 101272 2022.7
-
27. Automated evaluation of colon capsule endoscopic severity of ulcerative colitis using ResNet50.
Higuchi N, Hiraga H, Sasaki Y, Hiraga N, Igarashi S, Hasui K, Ogasawara K, Maeda T, Murai Y, Tatsuta T, Kikuchi H, Chinda D, Mikami T, Matsuzaka M, Sakuraba H, Fukuda S
PLoS One. 2022.6
-
Influence of Esophageal Endoscopic Submucosal Dissection on the Changes of Energy Metabolism during the Perioperative Period.
Sae Kudo, Daisuke Chinda, Tadashi Shimoyama, Kohei Yasuda, Kazuki Akitaya, Tetsu Arai, Kuniaki Miyazawa, Shiro Hayamizu, Miyuki Yanagimachi, Toshiaki Tsukamoto, Masatoshi Kaizuka, Yohei Sawada, Tetsuya Tatsuta, Keisuke Hasui, Hidezumi Kikuchi, Hiroto Hiraga, Hirotake Sakuraba, Tatsuya Mikami, Shinsaku Fukuda
Cancers 14 ( 8 ) 2022.4
-
Endoscopic and histopathologic features of Anti-PD-1-related collagenous colitis.
Hidezumi Kikuchi, Hirotake Sakuraba, Yui Akemoto, Kazuhiro Hosoi, Yasuhisa Murai, Kentaro Hoshi, Yukari Fukutoku, Taka Asari, Yohei Sawada, Keisuke Hasui, Tetsuya Tatsuta, Hiroto Hiraga, Daisuke Chinda, Tatsuya Mikami, Shinsaku Fukuda
DEN open 2 ( 1 ) e92 2022.4
-
Hepatic Macrophages Express Melanoma Differentiation-Associated Gene 5 in Nonalcoholic Steatohepatitis.
Shogo Kawaguchi, Hirotake Sakuraba, Momone Horiuchi, Jiangli Ding, Tomoh Matsumiya, Kazuhiko Seya, Chikara Iino, Tetsu Endo, Hidezumi Kikuchi, Shukuko Yoshida, Hiroto Hiraga, Shinsaku Fukuda, Tadaatsu Imaizumi
Inflammation 45 ( 1 ) 343 - 355 2022.2
-
＜一般演題抄録＞ 当科における関節リウマチに合併した医原性免疫不全関連リンパ増殖性疾患の解析
小笠原 公平, 髙畑 武功, 立田 卓登, 鎌田 耕輔, 蓮井 桂介, 平賀 寛人, 櫻庭 裕丈, 山形 和史, 玉井 佳子, 福田 眞作
弘前医学 72 ( 1-4 ) 102 2022
-
成人発症IgA血管炎消化管病変評価における小腸カプセル内視鏡の有用性
平賀 寛人, 蓮井 桂介, 村井 康久, 小笠原 公平, 樋口 直樹, 澤田 洋平, 立田 哲也, 菊池 英純, 平賀 典子, 珍田 大輔, 海老名 麻美, 櫻庭 裕丈
日本小腸学会学術集会プログラム・抄録集 6 ( 0 ) 44 - 44 2022
-
Tacrolimus Up-regulates Expression of TGFβ Receptor Type II via ERK, Providing Protection Against Intestinal Epithelial Injury.
Miwa Satake, Hirotake Sakuraba, Hiroto Hiraga, Shukuko Yoshida, Yui Akemoto, Shinji Ota, Yasuhisa Murai, Keisuke Hasui, Shogo Kawaguchi, Hidezumi Kikuchi, Shinsaku Fukuda
In vivo (Athens, Greece) 36 ( 4 ) 1684 - 1693 2022
-
Automated evaluation of colon capsule endoscopic severity of ulcerative colitis using ResNet50.
Naoki Higuchi, Hiroto Hiraga, Yoshihiro Sasaki, Noriko Hiraga, Shohei Igarashi, Keisuke Hasui, Kohei Ogasawara, Takato Maeda, Yasuhisa Murai, Tetsuya Tatsuta, Hidezumi Kikuchi, Daisuke Chinda, Tatsuya Mikami, Masashi Matsuzaka, Hirotake Sakuraba, Shinsaku Fukuda
PloS one 17 ( 6 ) e0269728 2022
-
今月の主題 炎症性腸疾患の鑑別診断 主題 炎症性腸疾患の画像所見と鑑別診断-びまん性炎症
菊池 英純, 三上 達也, 櫻庭 裕丈, 平賀 寛人, 蓮井 桂介, 村井 康久, 星 健太郎, 浅利 享, 澤田 洋平, 宮澤 邦昭, 立田 哲也, 珍田 大輔, 澤谷 学, 花畑 憲洋, 明本 由衣, 福田 眞作
胃と腸 56 ( 12 ) 1547 - 1553 2021.11
-
特集 消化管内視鏡治療-基本から高難度まで 捻転に対する内視鏡的整復術 胃軸捻転
三上 達也, 相原 智之, 笹田 貴史, 五十嵐 崇徳, 立田 哲也, 菊池 英純, 珍田 大輔, 平賀 寛人, 櫻庭 裕丈, 坂本 十一, 東野 博, 福田 眞作
消化器内視鏡 33 ( 13 ) 384 - 386 2021.11
-
特集 炎症性腸疾患の分子標的治療を総括する Ⅳ.接着分子阻害薬─ ベドリズマブの特性を生かしたIBD 治療
櫻庭 裕丈, 平賀 寛人, 蓮井 桂介, 菊池 英純, 村井 康久, 川口 章吾, 樋口 直樹, 明本 由衣, 福田 眞作
INTESTINE 25 ( 3 ) 267 - 274 2021.9
-
Esophageal achalasia with mucosal damage due to enteric-coated aspirin.
Tetsuya Tatsuta, Daisuke Chinda, Tatsuya Mikami, Shinya Suto, Kazuki Akitaya, Shohei Igarashi, Keisuke Hasui, Hidezumi Kikuchi, Hiroto Hiraga, Manabu Sawaya, Hirotake Sakuraba, Tadashi Shimoyama, Shinsaku Fukuda
Clinical journal of gastroenterology 14 ( 6 ) 1598 - 1601 2021.8
-
Long-term efficacy and tolerability of dose-adjusted thiopurine treatment in maintaining remission in inflammatory bowel disease patients with NUDT15 heterozygosity.
Takato Maeda, Hirotake Sakuraba, Hiroto Hiraga, Shukuko Yoshida, Yoichi Kakuta, Hidezumi Kikuchi, Shogo Kawaguchi, Keisuke Hasui, Tetsuya Tatsuta, Daisuke Chinda, Tatsuya Mikami, Shinsaku Fukuda
Intestinal research 20 ( 1 ) 90 - 100 2021.1
-
Tryptanthrin suppresses double-stranded RNA-induced CXCL10 expression via inhibiting the phosphorylation of STAT1 in human umbilical vein endothelial cells.
Shogo Kawaguchi, Hirotake Sakuraba, Hidezumi Kikuchi, Noriyuki Numao, Taka Asari, Hiroto Hiraga, Jiangli Ding, Tomoh Matsumiya, Kazuhiko Seya, Shinsaku Fukuda, Tadaatsu Imaizumi
Molecular immunology 129 32 - 38 2021.1
-
Cyclosporine protects from intestinal epithelial injury by modulating butyrate uptake via upregulation of membrane monocarboxylate transporter 1 levels.
12. Ota S, Sakuraba H, Hiraga H, Yoshida S, Satake M, Akemoto Y, Tanaka N, Watanabe R, Maeda T, Murai Y, Ueno K, Niioka T, Hayakari M, Ishiguro Y, Fukuda S
Biochem Biophys Rep. 2020.12
-
Cyclosporine protects from intestinal epithelial injury by modulating butyrate uptake via upregulation of membrane monocarboxylate transporter 1 levels.
Shinji Ota, Hirotake Sakuraba, Hiroto Hiraga, Shukuko Yoshida, Miwa Satake, Yui Akemoto, Nahoko Tanaka, Rina Watanabe, Maeda Takato, Yasuhisa Murai, Kayo Ueno, Takenori Niioka, Makoto Hayakari, Yoh Ishiguro, Shinsaku Fukuda
Biochemistry and biophysics reports 24 100811 - 100811 2020.12
-
Usefulness of serum opsonic activity measured by chemiluminescence method to assess the invasiveness of colorectal endoscopic mucosal dissection.
Daisuke Chinda, Tadashi Shimoyama, Tetsu Arai, Kaori Sawada, Kazuki Akitaya, Sae Kudo, Kohei Yasuda, Kuniaki Miyazawa, Naoki Akimoto, Satoshi Sato, Shiro Hayamizu, Tetsuya Tatsuta, Hidezumi Kikuchi, Hiroto Hiraga, Manabu Sawaya, Hirotake Sakuraba, Tatsuya Mikami, Shigeyuki Nakaji, Shinsaku Fukuda
Free radical research 54 ( 11-12 ) 810 - 817 2020.12
-
Case report of lanthanum deposition in the esophagus.
Tetsuya Tatsuta, Tatsuya Mikami, Daisuke Chinda, Kazuki Akitaya, Shohei Igarashi, Keisuke Hasui, Hidezumi Kikuchi, Hiroto Hiraga, Manabu Sawaya, Hirotake Sakuraba, Tadashi Shimoyama, Tosihiro Haga, Hiroshi Kijima, Shinsaku Fukuda
Clinical journal of gastroenterology 13 ( 5 ) 683 - 687 2020.10
-
Sa1653 THE USEFULNESS OF TOTAL INTESTINAL SURVEY USING COLON CAPSULE ENDOSCOPY~A FINAL REPORT ON THE TOTAL (TOTAL OBSERVATION FROM INTESTINE TO ANAL LESION) STUDY~
Hiroto Hiraga, Hirotake Sakuraba, Naoki Higuchi, Takato Maeda, Yasuhisa Murai, Rina Watanabe, Tetsuya Tatsuta, Keisuke Hasui, Hidezumi Kikuchi, Manabu Sawaya, Noriko Hiraga, Daisuke Chinda, Tatsuya Mikami, Shinsaku Fukuda
Gastroenterology 158 ( 6 ) S - 370 2020.5
-
Melanoma Differentiation-Associated Gene 5 Positively Modulates TNF-α-Induced CXCL10 Expression in Cultured HuH-7 and HLE Cells.
Shogo Kawaguchi, Hirotake Sakuraba, Toshihiro Haga, Tomoh Matsumiya, Kazuhiko Seya, Tetsu Endo, Naoya Sawada, Chikara Iino, Hidezumi Kikuchi, Hiroto Hiraga, Shinsaku Fukuda, Tadaatsu Imaizumi
Inflammation 42 ( 6 ) 2095 - 2104 2019.12
-
Diagnostic approach for patients with unidentified fever according to the classical criteria of fever of unknown origin in the field of autoimmune disorders.
Rina Watanabe, Hirotake Sakuraba, Hiroto Hiraga, Dai Kishida, Shinji Ota, Keisuke Hasui, Hidezumi Kikuchi, Yui Akemoto, Nahoko Tanaka, Takato Maeda, Yasuhisa Murai, Shukuko Yoshida, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Yoh Ishiguro, Shinsaku Fukuda
Immunological medicine 42 ( 4 ) 176 - 184 2019.12
-
Diagnostic approach for patients with unidentified fever according to the classical criteria of fever of unknown origin in the field of autoimmune disorders.
Rina Watanabe, Hirotake Sakuraba, Hiroto Hiraga, Dai Kishida, Shinji Ota, Keisuke Hasui, Hidezumi Kikuchi, Yui Akemoto, Nahoko Tanaka, Takato Maeda, Yasuhisa Murai, Shukuko Yoshida, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Yoh Ishiguro, Shinsaku Fukuda
Immunological medicine 42 ( 4 ) 176 - 184 2019.12
-
Melanoma Differentiation-Associated Gene 5 Positively Modulates TNF-α-Induced CXCL10 Expression in Cultured HuH-7 and HLE Cells.
Shogo Kawaguchi, Hirotake Sakuraba, Toshihiro Haga, Tomoh Matsumiya, Kazuhiko Seya, Tetsu Endo, Naoya Sawada, Chikara Iino, Hidezumi Kikuchi, Hiroto Hiraga, Shinsaku Fukuda, Tadaatsu Imaizumi
Inflammation 42 ( 6 ) 2095 - 2104 2019.12
-
Long-term maintenance of the mucosal healing induced by azacitidine therapy in a patient with intestinal Behçet's-like disease accompanied with myelodysplastic syndrome involving trisomy 8.
Nahoko Tanaka, Hirotake Sakuraba, Hiroto Hiraga, Ko Mayama, Hidezumi Kikuchi, Dai Kishida, Yui Akemoto, Keisuke Hasui, Shinji Ota, Rina Watanabe, Yasuhisa Murai, Takato Maeda, Kosuke Kamata, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Kazufumi Yamagata, Yoh Ishiguro, Masanori Tanaka, Shinsaku Fukuda
Immunological medicine 42 ( 3 ) 135 - 141 2019.9
-
A case of celiac disease with type I enteropathy-associated T-cell lymphoma in a Japanese male patient.
Hiroto Hiraga, Hirotake Sakuraba, Nahoko Tanaka, Rina Watanabe, Yui Akemoto, Shinji Ota, Hidezumi Kikuchi, Manabu Sawaya, Noriko Hiraga, Daisuke Chinda, Norihiro Hanabata, Tatsuya Mikami, Tadashi Shimoyama, Takenori Takahata, Masanori Tanaka, Shinsaku Fukuda
Immunological medicine 42 ( 3 ) 142 - 147 2019.9
-
Long-term maintenance of the mucosal healing induced by azacitidine therapy in a patient with intestinal Behçet's-like disease accompanied with myelodysplastic syndrome involving trisomy 8.
Nahoko Tanaka, Hirotake Sakuraba, Hiroto Hiraga, Ko Mayama, Hidezumi Kikuchi, Dai Kishida, Yui Akemoto, Keisuke Hasui, Shinji Ota, Rina Watanabe, Yasuhisa Murai, Takato Maeda, Kosuke Kamata, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Kazufumi Yamagata, Yoh Ishiguro, Masanori Tanaka, Shinsaku Fukuda
Immunological medicine 42 ( 3 ) 135 - 141 2019.9
-
A case of celiac disease with type I enteropathy-associated T-cell lymphoma in a Japanese male patient.
Hiroto Hiraga, Hirotake Sakuraba, Nahoko Tanaka, Rina Watanabe, Yui Akemoto, Shinji Ota, Hidezumi Kikuchi, Manabu Sawaya, Noriko Hiraga, Daisuke Chinda, Norihiro Hanabata, Tatsuya Mikami, Tadashi Shimoyama, Takenori Takahata, Masanori Tanaka, Shinsaku Fukuda
Immunological medicine 42 ( 3 ) 142 - 147 2019.9
-
Successful adalimumab treatment and usefulness of capsule endoscopy for gut inflammation concomitant with ankylosing spondylitis.
Shinji Ota, Hirotake Sakuraba, Hiroto Hiraga, Keisuke Hasui, Miwa Satake, Norihiro Hanabata, Yui Akemoto, Rina Watanabe, Nahoko Tanaka, Yoh Ishiguro, Masanori Tanaka, Shinsaku Fukuda
Modern rheumatology 29 ( 4 ) 708 - 713 2019.7
-
A case of nivolumab-associated colitis, which relapsed after mucosal healing and was then successfully treated with mesalazine.
Hidezumi Kikuchi, Hirotake Sakuraba, Yui Akemoto, Yasuhisa Murai, Yukari Fukutoku, Taka Asari, Tetsuya Tatsuta, Keisuke Hasui, Hiroto Hiraga, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Masanori Tanaka, Shinsaku Fukuda
Immunological medicine 42 ( 1 ) 39 - 44 2019.3
-
A case of nivolumab-associated colitis, which relapsed after mucosal healing and was then successfully treated with mesalazine.
Hidezumi Kikuchi, Hirotake Sakuraba, Yui Akemoto, Yasuhisa Murai, Yukari Fukutoku, Taka Asari, Tetsuya Tatsuta, Keisuke Hasui, Hiroto Hiraga, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Masanori Tanaka, Shinsaku Fukuda
Immunological medicine 42 ( 1 ) 39 - 44 2019.3
-
Gastric Focal Neutrophil Infiltration and Wide Duodenal Gastric Foveolar Metaplasia Are Histologic Discriminative Markers for Crohn's Disease and Behçet's Disease.
Yui Akemoto, Hirotake Sakuraba, Masanori Tanaka, Hiroto Hiraga, Hidezumi Kikuchi, Satoko Morohashi, Shinji Ota, Keisuke Hasui, Miwa Satake, Rina Watanabe, Nahoko Tanaka, Shogo Kawaguchi, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Yoh Ishiguro, Hiroshi Kijima, Shinsaku Fukuda
Digestion 100 ( 3 ) 210 - 219 2019
-
Vitamin A Deficiency Impairs Host Resistance to <i>Listeria Monocytogenes</i> Infection Through Excessive Apoptosis of Macrophages
Tanaka Nahoko, Hiraga Hiroto, Sakuraba Hirotake, Murai Yasuhisa, Maeda Takato, Watanabe Rina, Ota Shinji, Akemoto Yui, Hasui Keisuke, Yoshida Shukuko, Asano Krisana, Nakane Akio, Fukuda Shinsaku
Hirosaki Medical Journal 69 ( 1 ) 163 - 171 2019
-
Influence of gastric endoscopic submucosal dissection on serum opsonic activity measured by chemiluminescence
Arai Tetsu, Chinda Daisuke, Shimoyama Tadashi, Sawada Kaori, Akitaya Kazuki, Miyazawa Kuniaki, Akimoto Naoki, Sato Satoshi, Hayamizu Shiro, Tatsuta Tetsuya, Kikuchi Hidezumi, Hiraga Hiroto, Sawaya Manabu, Sakuraba Hirotake, Mikami Tatsuya, Nakaji Shigeyuki, Fukuda Shinsaku
Journal of Clinical Biochemistry and Nutrition 64 ( 2 ) 180 - 185 2019
-
Gastric Focal Neutrophil Infiltration and Wide Duodenal Gastric Foveolar Metaplasia Are Histologic Discriminative Markers for Crohn's Disease and Behçet's Disease.
Yui Akemoto, Hirotake Sakuraba, Masanori Tanaka, Hiroto Hiraga, Hidezumi Kikuchi, Satoko Morohashi, Shinji Ota, Keisuke Hasui, Miwa Satake, Rina Watanabe, Nahoko Tanaka, Shogo Kawaguchi, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Yoh Ishiguro, Hiroshi Kijima, Shinsaku Fukuda
Digestion 100 ( 3 ) 210 - 219 2019
-
クローン病小腸病変のMRI拡散強調画像による炎症線維化バランス評価の有用性
蓮井 桂介, 樋口 直樹, 有明 千鶴, 立田 哲也, 澤谷 学, 珍田 大輔, 三上 達也, 石黒 陽, 田中 正則, 福田 眞作, 櫻庭 裕丈, 平賀 寛人, 菊池 英純, 明本 由衣, 浅利 享, 渡邊 里奈, 前田 高人, 星 健太郎
日本小腸学会学術集会プログラム・抄録集 3 ( 0 ) 63_1 - 63_1 2019
-
大腸カプセル内視鏡による全腸観察を利用したNSAIDs起因性腸病変評価の有用性
平賀 寛人, 澤谷 学, 平賀 典子, 珍田 大輔, 三上 達也, 海老名 麻美, 福田 眞作, 櫻庭 裕丈, 有明 千鶴, 前田 高人, 村井 康久, 渡邊 里奈, 立田 哲也, 蓮井 桂介, 菊池 英純
日本小腸学会学術集会プログラム・抄録集 3 ( 0 ) 41_2 - 41_2 2019
-
免疫チェックポイント阻害剤投与後に発症した小腸炎の3例
菊池 英純, 三上 達也, 福田 眞作, 櫻庭 裕丈, 明本 由衣, 浅利 享, 蓮井 桂介, 立田 哲也, 平賀 寛人, 澤谷 学, 珍田 大輔
日本小腸学会学術集会プログラム・抄録集 3 ( 0 ) 43_1 - 43_1 2019
-
Successful treatment with tacrolimus of refractory pyoderma gangrenosum with pouchitis after restorative proctocolectomy for ulcerative colitis.
Satake M, Sakuraba H, Hiraga H, Tarakita N, Akemoto Y, Ota S, Hasui K, Nishiya D, Hayamizu S, Kikuchi H, Sawaya M, Chinda D, Mikami T, Shimoyama T, Fukuda S
Immunological medicine 41 ( 3 ) 142 - 146 2018.9
-
Estimation of perioperative invasiveness of colorectal endoscopic submucosal dissection evaluated by energy metabolism
Chinda Daisuke, Kawaguchi Shogo, Kikuchi Hidezumi, Hiraga Hiroto, Sawaya Manabu, Sakuraba Hirotake, Mikami Tatsuya, Fukuda Shinsaku, Shimoyama Tadashi, Miyazawa Kuniaki, Arai Tetsu, Hayamizu Shiro, Yanagimachi Miyuki, Tsukamoto Toshiaki, Akitaya Kazuki, Tatsuta Tetsuya
Ｊｏｕｒｎａｌ ｏｆ Ｃｌｉｎｉｃａｌ Ｂｉｏｃｈｅｍｉｓｔｒｙ ａｎｄ Ｎｕｔｒｉｔｉｏｎ 63 ( 2 ) 164 - 167 2018
-
Prediction of maintained mucosal healing in patients with Crohn's disease under treatment with infliximab using diffusion-weighted magnetic resonance imaging.
Sakuraba H, Ishiguro Y, Hasui K, Hiraga H, Fukuda S, Shibutani K, Takai Y
Digestion 89 ( 1 ) 49 - 54 2014
-
関節リウマチ患者に対する生物学的製剤による治療は臨床的寛解時における MRI で検出される潜在的関節炎を抑制する
蓮井 桂介, 櫻庭 裕丈, 石黒 陽, 平賀 寛人, 福田 眞作
弘前医学 64 ( 2 ) 119 - 126 2014
-
A case of pancreatic serous cystadenoma diagnosed as IPMN origin invasive pancreatic carcinoma by preoperative imaging
27 ( 1 ) 59 - 61 2011.6
-
Cyclosporine regulates intestinal epithelial apoptosis via TGF-beta-related signaling.
Yuki Satoh, Yoh Ishiguro, Hirotake Sakuraba, Shogo Kawaguchi, Hiroto Hiraga, Shinsaku Fukuda, Akio Nakane
American journal of physiology. Gastrointestinal and liver physiology 297 ( 3 ) G514 - G519 2009.9
-
Cyclosporine regulates intestinal epithelial apoptosis via TGF-beta-related signaling.
Satoh Y, Ishiguro Y, Sakuraba H, Kawaguchi S, Hiraga H, Fukuda S, Nakane A
American journal of physiology. Gastrointestinal and liver physiology 297 ( 3 ) G514 - 9 2009.9
-
Transforming growth factor (TGF)-β receptors are suppressed in the refractory cases with ulcerative colitis
Shimaya Koji, Ishiguro Yoh, Kawaguchi Shogo, Sato Yuki, Hiraga Hiroto, Yamaguchi Satoko, Sakuraba Hirotake, Fujita Hitoshi, Yamagata Kazufumi, Fukuda Shinsaku
Hirosaki medical journal 59 ( 2 ) 90 - 97 2008
-
All-trans-retinoic acid (atRA) increases host resistance to Listeria monocytogenes infection
Hiraga Hiroto, Sashinami Hiroshi, Hu Dong-Liang, Ishiguro Yoh, Wakabayashi Koichi, Munakata Akihiro, Nakane Akio
弘前医学 59 ( 0 ) S244 - 252 2007
-
Pollution of enteropathogenic bacteria in meats and egg in Japan and China
Hu Dong-Liang, Qian Ai-Dong, San Xiao-Feng, Narita Kouji, Sashinami Hiroshi, Osanai Arihiro, Abe Yukiko, Hiraga Hiroto, Kudo Kohsei, Liu Yong, Nakane Akio
Hirosaki medical journal 59 ( 1 ) 1 - 6 2007
-
Macrophage migration inhibitory factor has a proinflammatory activity via the p38 pathway in glucocorticoid-resistant ulcerative colitis.
Ishiguro Y, Ohkawara T, Sakuraba H, Yamagata K, Hiraga H, Yamaguchi S, Fukuda S, Munakata A, Nakane A, Nishihira J
Clinical immunology (Orlando, Fla.) 120 ( 3 ) 335 - 41 2006.9
-
[Successful treatment of 5-FU intraarterial infusion on the third postoperative day for a patient with multiple liver metastases from colon cancer and high risk of liver failure].
Mori T, Munakata M, Kasai M, Nozaki T, Kawamura S, Sawamura N, Hiraga H, Sakata Y
Gan to kagaku ryoho. Cancer & chemotherapy 31 ( 7 ) 1101 - 3 2004.7