Updated on 2024/11/05

写真a

 
MURAKAMI Manabu
 
Affiliation
Graduate School of Medicine F F

Degree

  • 医学博士(内科学)

Research Areas

  • Life Science / Pharmacology

Professional Memberships

  • 日本生理学会

  • 日本薬理学会

Papers

  • A novel binding site between the voltage-dependent calcium channel CaV1.2 subunit and Cavβ2 subunit discovered using a new analysis method for protein-protein interactions.

    Murakami AM, Nagatomo K, Miyoshi I, Itagaki S, Niwa Y, Murakami M.

    Sci Rep   13   13986   2023.9

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    Language:English   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • A simple, dual direct expression plasmid system in prokaryotic and mammalian cells

    Murakami M, Murakami AM, Yonekura M, Miyoshi I, Itagaki S, Niwa Y.

    PNAS Nexus   2   1 - 3   2023.6

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  • Enhanced β-adrenergic response in mice with dominant-negative expression of the PKD2L1 channel

    Murakami M, Murakami AM, Nemoto T, Ohba T, Yonekura M, Toyama Y, Tomita H, MatsuzakiY, Sawamura D, Hirota K, Itagaki S, Asada Y, Miyoshi I.

    PLoS One   17 ( 1 )   e0261668   2022.4

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  • Rapid method for plasmid DNA recombination (Murakami-system)

    Murakami AM, Yonekura M, Nagatomo K, Niwa Y, Itagaki S, Murakami M.

    MethodsX   10 ( 1 )   102167 - 102167   2023.4

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  • A dual prokaryotic (E.coli) expression system (pdMAX)

    Murakami M, Murakami AM, Itagaki S.

    PLoS One   16 ( 10 )   e0258553   2021.11

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  • Decreased cardiac pacemaking and attenuated β-adrenergic response in TRIC-A knockout mice.

    15 ( 12 )   e0244254   2020.12

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  • Molecular cloning of medaka orexin and orexin receptor and decreased spontaneous movement in response to an orexin inhibitor

    71   55 - 64   2020.9

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    Language:English   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Establishment of cardiac action potential recording using a membrane potential indicator in the mouse sinoatrial node

    70   163 - 171   2020.2

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    Language:English   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • A simple and dual expression plasmid system in prokaryotic (E. coli) and mammalian cells

    14 ( 5 )   e0216169   2019.5

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    Language:English   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Protocols with pgMAX plasmid

    2019.5

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    Language:English   Publishing type:Research paper (scientific journal)   Kind of work:Single Work  

  • Medaka as a model for ECG analysis and the effect of verapamil

    Yonekura M, Kondoh N, Han C, Ohba T, Ono K, Itagaki S, Tomita H, Murakami M.

    Journal of Pharmacological Sciences   2018.2

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  • Stromal interaction molecule 1 haploinsufficiency causes maladaptive response to pressure overload

    Ohba T, Watanabe H, Murakami M, Iino K, Adachi T, Baba Y, Kurosaki T, Ono K, Ito H.

    PLOS ONE   16   e0187950   2017.11

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  • A comparative study of the internal ribosome entry site-containing expression system

    Murakami M, Murakami AM, Ohba T

    Hirosaki Medical Journal   68   44 - 51   2017.9

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  • β-arrestins negatively control human adrenomedullin type 1-receptor internalization

    Kuwasako K, Kitamura K, Nagata S, Sekiguchi T, Danfeng Z, Murakami M, Hattori Y, Kato J.

    Biochem Biophys Res Commun.   ( 487 )   438 - 443   2017.5

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  • Interferon (IFN)-induced protein 35 (IFI35) negatively regulates IFN-b-phosphorylated STAT1-RIG-I-CXCL10/CCL5 axis in U373MG astrocytoma cells treated with polyinosinic-polycytidylic acid.

    Shirai K , Shimada T, Yoshida H, Hayakari R, Matsumiya T, Tanji K, Murakami M, Tanaka H, Imaizumi T

    Brain Res   658   60 - 67   2017.3

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  • Modified parasympathetic nervous system in Goto-Kakizaki diabetic rats.

    Han C, Inaba W, Yonekura M, Ogata Y, Ohba T, Kushikata T, Niwa H, Yanagisawa T, Tomita H, Itagaki S, Hirota K, Akai H, Mizukami H, and Murakami M.

    Hirosaki Medical Journal   68   1 - 5   2017.3

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  • A convenient isolation and culture method of neonatal mouse cardiomyocytes.

    67   147 - 152   2017.1

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Effects of enflurane on cardiac nervous activety in mice.

    Ogata Y, Yonekura M, Yamaki R, Han C, Fujiwara T, Seya K, Niwa H, Kushikata T, Imaizumi T, Hirota K, Tomita H, Murakami M.

    Hirosaki Medical Journal   67   153 - 157   2017.1

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  • Effects of halothane anesthesia on electrocardiogram parameters in mice.

    Nozaki S, Ogata Y, Yonekura M, Han C, Niwa H, Kushikata T, Hirota K, Matsuzaki Y, Tomita H, Imaizumi T, Itagaki S, Sawamura D, Murakami M.

    Hirosaki Medical Journal   67   129 - 135   2017.1

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  • Stromal interaction molecule 1 haploinsufficiency causes maladaptive response to pressure overload.

    Ohba T, Watanabe H, Murakami M, Iino K, Adachi T, Baba Y, Kurosaki T, Ono K, Ito H.

    PLoS One   12   1 - 14   2017

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  • Interferon (IFN)-induced protein 35 (IFI35), a type I interferon-dependent transcript, upregulates inflammatory signaling pathways by activating Toll-like receptor 3 in human mesangial cells.

    Imaizumi T, Yano C, Numata A, Tsugawa K, Hayakari R, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Kawaguchi S, Murakami M, Tanaka H. 

    Kidney Blood Press Res.   2016.10

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  • Inhibitory effects of two G protein-coupled receptor kinases on the cell surface expression and signaling of the human adrenomedullin receptor.

    Kuwasako K, Sekiguchi T, Nagata S, Danfeng Z, Hayashi H, Murakami M, Hattori Y, Kitamura K, Kato J.

    Biochem Biophys Res Commun.   470   894 - 899   2016.10

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  • The cardiorespiratory responses to inhalation and pentobarbital anesthesia in the mouse.

    Han C, Ogata Y, Niwa H, Kushikata T, Watanabe H, Imizumi T, Hirota K, Ono K, Ohba T, Murakami M.

    Hirosaki Medical Journal   67   77 - 85   2016.10

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  • Interferon-stimulated gene 15, a type I interferon-dependent transcript, is involved in the negative feedback loop regulating inflammatory cascades via Toll-like receptor 3 activation in human mensangial cells.

    Imaizumi T, Shimada T, Matsumiya T, Yoshida H, Tsugawa K, Watanabe S, Tsuruga K, Kawaguchi S, Murakami M, Joh K, Tanaka H.

    Nephron Experimental Nephrology   2016

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  • Modified sympathetic nerve regulation in AKAP5-null mice

    Han C, Tomita H, Ohba T, Nishizaki K, Ogata Y, Matsuzaki Y, Sawamura D, Yanagisawa T, Osanai T, Imaizumi T, Matsubara A, Adachi T, Ono K, Okumura K, Murakami M.

    Biochemical and Biophysical Research Communications   ( 469 )   897 - 902   2016

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  • Desferrioxamine, an iron chelator, induces CXCL8 expression in U373MG Human astrocytoma cells.

    Onda K, Yoshida H, Hayakari R, Xing F, Wang L, Matsumiya T, Kawaguchi S, Murakami M, Imaizumi T.

    Hirosaki Medical Journal   2016

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  • Inhibitory effects of two G protein-coupled receptor kinases on the cell surface expression and signaling of the human adrenomedullin receptor.

    Kuwasako K, Sekiguchi T, Nagata S, Danfeng Z, Hayashi H, Murakami M, Hattori Y, Kitamura K, Kato J.

    Biochemical and Biophysical Research Communications   2016

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  • 1-Methyl-2-undecyl-4(1H)-quinolone, a derivative of quinolone alkaloid evocarpine, attenuates high phosphate-induced calcification of human aortic valve interstitial cells by inhibiting phosphate cotransporter PiT-1

    Seya K, Furukawa K, Chiyoya M, Yu Z, Kikuchi H, Daitoku K, Motomura S, Murakami M, Oshima Y, Fukuda I

    Journal of Pharmacological Science   2016

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  • Involvement of the orexin system in sympathetic nerve regulation

    Murakami M, Ohba T, Kushikata T, Niwa H, Kurose A, Imaizumi T, Watanabe H, Yanagisawa T, Nakaji S, Ono K, Hirota K

    Biochemical and Biophysical Research Communications   2015.10

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  • Desferrioxamine, an iron chelator, inhibits CXCL10 expressioninduced by polyinosinic–polycytidylic acid in U373MG humanastrocytoma cells

    Imaizumi T, Sakashita N, Mushiga Y, Yoshida H, Hayakari R, Xing F, Wang L, Matsumiya T, Tanji K, Chiba Y, Furudate K, Kawaguchi S, Murakami M, Tanaka H

    Neurosciense Research   2015.10

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  • Modified autonomic regulation in mice mutated in the beta4 subunit of the lh/lh calcium channel

    Murakami M, Suzuki T, Wu T-W, Kuwasako K, Takahashi E, Watanabe H, Murakami AM, Miyoshi I, Yanagisawa T, Sasano H, Ono K, Ohba T

    Biochemical and Biophysical Research Communications   2015.10

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  • Involvement of the histamine H1 receptor in the regulation of sympathetic nerve activity

    Murakami M, Yoshikawa T, Nakamura T, Ohba T, Matsuzaki Y, Sawamura D, Kuwasako K, Yanagisawa T, Ono K, Nakaji S, Yanai K

    Biochemical and Biophysical Research Communications   2015.10

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  • Desferrioxamine, an iron chelator, inhibits CXCL10 expression induced by polyinosinic-polycytidylic acidin U373MG human astrocytoma cells

    Imaizumi T, Sakashita N, Mushiga Y, Yoshida H, Hayakari R, Xing F, Wang L, Matsumiya T, Tanji K, Chiba Y, Furudate K, Kawaguchi S, Murakami M, Tanaka H

    Neuroscience Research   2015.10

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  • Comparison of the Effects of Isoflurane Inhalation, Pentobarbital and a Medetomidine-Midazolam-Butorphanol Combination Anesthesia on Electrocardiograms in Mice

    Shintaku T, Ohba T, Niwa H, Kushikata T, Hirota K, Ono K, Matsuzaki Y, Imaizumi T, Sawamura D, Murakami M

    2015.10

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  • Effects of isoflurane inhalation anesthesia on mouse ECG

    Shintaku T, Ohba T, Niwa H, Kushikata T, Hirota K, Ono K, Matsuzaki Y, Imaizumi T, Sawamura D, Murakami M

    2015.10

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  • Effects of Propofol on Electrocardiogram Measures in Mice

    Shintaku T, Ohba T, Niwa H, Kushikata T, Hirota K, Ono K, Matsuzaki Y, Imaizumi T, Kuwasako K, Sawamura D, Murakami M

    Journal of Pharmacological Science   2014.12

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  • Involvement of endothelin-1 in adrenal catecholamine regulation

    Murakami M, Nemoto T, Ohba T, Niwa H, Kushikata T, Ono K, Watanabe H, Hirota K

    Hirosaki Medical Journal   2014.10

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  • Inhalation anesthesia is preferable for recording rat cardiac function using an electrocardiogram

    Murakami M, Niwa H, Kushikata T, Watanabe H, Hirota K, Ono K, Ohba T

    2014.10

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  • Up-Regulation of NaV1.7 Sodium Channels Expression by Tumor Necrosis Factor-α in Cultured Bovine Adrenal Chromaffin Cells and Rat Dorsal Root Ganglion Neurons.

    Tamura R, Nemoto T, Maruta T, Onizuka S, Yanagita T, Wada A, Murakami M, Tsuneyoshi I

    2014.9

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Books

  • New Pharmacology

    Manabu Murakami( Role: Joint author)

    Nishimura Syuppann  2018 

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    Language:Japanese Book type:Textbook, survey, introduction

Awards

  • 弘前医学優秀論文賞

    2015.06