日本生殖医学会

DNA damage in human sperm: The sperm chromosome assay

Seiji Watanabe

Reproductive Medicine and Biology   21 ( 1 )   2022.4

A detailed pathway and termination of thoracic duct in a Japanese female cadaver with situs inversus totalis.

Narita H, Watanabe S, Umemura K, Shimoda H

Anatomical science international   95 ( 3 )   425 - 428   2020.6

Modified permeable cryoprotectant-free vitrification method for three or fewer ejaculated spermatozoa from cryptozoospermic men and 7-year follow-up study of 14 children born from this method.

Ohno M, Tanaka A, Nagayoshi M, Yamaguchi T, Takemoto Y, Tanaka I, Watanabe S, Itakura A

Human reproduction (Oxford, England)   35 ( 5 )   1019 - 1028   2020.5

Can cytoplasmic donation rescue aged oocytes?

Atsushi Tanaka, Seiji Watanabe

Reproductive Medicine and Biology   18   128 - 139   2019

Widespread anorectal lymphovascular networks and tissue drainage: analyses from submucosal India ink injection and indocyanine green fluorescence imaging.

Sato K, Shimoda H, Miura T, Sakamoto Y, Morohashi H, Watanabe S, Narita H, Mitsuhashi Y, Umemura K, Hakamada K

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland   23 ( 6 )   1334 - 1345   2021.6

Where does extra X in klinefelter syndrome come from?

A Tanaka, M Nagayoshi, I Tanaka, T Yamaguchi, M Ohno, S Watanabe

Fertility and Sterility   112   e256 - e256   2019.12

受精の異常

米本昌平、田中　温、渡邉誠二、大野基晴、市山卓彦、山口貴史、永吉　基

臨床産婦人科   73 ( 3 )   317 - 323   2019.4

Ninety babies born after round spermatid injection into oocytes: survey of their development from fertilization to 2 years of age

A Tanaka, K Suzuki, M Nagayoshi, A Tanaka, Y Takemoto, S Watanabe, S Takeda, M Irahara, N Kuji, Z Yamagata, R Yanagimachi

Fertility and Sterility   110 ( 3 )   443 - 451   2018.8

〈一般演題抄録〉血管網含有ヒトiPS 細胞由来３次元心筋組織の生体移植における分子形態学的解析

成田 大一, 横山 淳也, 宮川 繁, 渡邉 誠二, 澤 芳樹, 明石 満, 下田 浩

弘前医学   68 ( 2 )   2018

The inability of human sperm with chromosomal abnormalities to penetrate the oocyte in assisted reproductive technology (ART): risk factors and the role of seminal plasma

Seiji Watanabe*, Atsushi Fukui, Rika Nakamura, Rie Fukuhara and Ayano Funamizu

Journal of Mammalian Ova Research   34 ( 2 )   65 - 73   2017.11

Engraftment and morphological development of vascularized human iPS cell-derived 3D-cardiomyocyte tissue after xenotransplantation

Hirokazu Narita, Fumiaki Shima, Junya Yokoyama, Shigeru Miyagawa, Yoshinari Tsukamoto, Yasushi Takamura, Ayami Hiura, Ken Fukumoto, Tomohiro Chiba, Seiji Watanabe, Yoshiki Sawa, Mitsuru Akashi & Hiroshi Shimoda

Scientific reports   7 ( 13708 )   1 - 9   2017.10

Engraftment and morphological development of vascularized human iPS cell-derived 3D-cardiomyocyte tissue after xenotransplantation.

Narita H, Shima F, Yokoyama J, Miyagawa S, Tsukamoto Y, Takamura Y, Hiura A, Fukumoto K, Chiba T, Watanabe S, Sawa Y, Akashi M, Shimoda H

Scientific reports   7 ( 1 )   13708   2017.10

Genetical analysis of extra X in Klinefelter Syndrome:47XXY

Tanaka A, Nagayoshi M, Yamaguchi T, Ichiyama T, Ohno M, Watanabe S

Human Reproduction   32   i420 - i420   2017.10

Microanatomical profiles on the lymphatic system in the human ampulla of Vater (immunohistochemistry and scanning electron microscopy).

Kagiya T, Shimoda H, Narita H, Odagiri T, Watanabe S, Ishido K, Kudo D, Kimura N, Wakiya T, Hakamada K

Journal of hepato-biliary-pancreatic sciences   24 ( 10 )   570 - 575   2017.10

Does the extra X in Klinefelter Syndrome (KS) patients originate only paternally?

A. Tanaka, M. Nagayoshi, I. Tanaka, T. Yamaguchi, T. Ichiyama, M. Ohno, S. Watanabe

Fertility and Sterility   108 ( 3 )   e128 - e128   2017.9

Microanatomical profiles on the lymphatic system in the human ampulla of Vater (immunohistochemistry and scanning electron microscopy)

Takuji Kagiya, Hiroshi Shimoda, Hirokazu Narita, Tadashi Odagiri, Seiji Watanabe, Keinosuke Ishido, Daisuke Kudo, Norihisa Kimura, Taiichi Wakiya, Kenichi Hakamada

Journal Hepatobiliary Pancreatic Science   24 ( 10 )   570 - 575   2017.8

Genetical analysis of extra X in Klinefelter Syndrome:47XXY

A. Tanaka, M. Nagayoshi, T. Yamaguchi, T. Ichiyama, M. Ohno, S. Watanabe

Human Reproduction   32   i420 - i420   2017.7

Genetic risk of Klinefelter Syndrome in ART

Miki, Tamito; Nagayoshi, Motoi; Takemoto, Yoichi; Yamaguchi, Takashi; Takeda, Satoru; Watanabe, Seiji; Tanaka, Atsushi

Reproductive Medicine and Biology   16 ( 2 )   188 - 195   2017.4

Genetic risk of Klinefelter's syndrome in assisted reproductive technology.

Miki T, Nagayoshi M, Takemoto Y, Yamaguchi T, Takeda S, Watanabe S, Tanaka A

Reproductive medicine and biology   16 ( 2 )   188 - 195   2017.4

Hereditary risk in icsi with sperm from non-mosaic Klinefelter syndrome patients

T. Miki, A. Tanaka, M. Nagayoshi, S. Watanabe

Fertility and Sterility   106 ( 3 )   e64 - e64   2016.10

Reconsidering of human round spermatid injection into the oocyte (ROSI)

A. Tanaka, M. Nagayoshi, Y. Takemoto, I. Tanaka, T. Miki, T. Yamaguchi, H. Kusunoki, S. Watanabe

Human Reproduction   31   i161 - i161   2016.7

Fourteen babies born after round spermatid injection into human oocytes

Atsushi Tanaka, Motoi Nagayoshi, Youichi Takemoto, Izumi Tanaka, Hiroshi Kusunoki, Seiji Watanabe, Keiji Kuroda, Satoru Takeda, Masahiko Ito, Ryuzo Yanagimachi

PNAS   112   14629 - 14634   2015.12

Fourteen babies born after round spermatid injection into human oocytes.

Tanaka A, Nagayoshi M, Takemoto Y, Tanaka I, Kusunoki H, Watanabe S, Kuroda K, Takeda S, Ito M, Yanagimachi R

Proceedings of the National Academy of Sciences of the United States of America   112 ( 47 )   14629 - 34   2015.11

Development of new procedure to reduce the amount of recipient cytoplasm (mitochondria) at the M-II karyoplast transfer for the treatment of mitochondrial diseases

A. Tanaka, M. Nagayoshi, Y. Takemoto, H. Kusunoki, S. Watanabe

Fertility and Sterility   104   e182 - e182   2015.10

Clinical outcome of treatments for azoospermia

A. Tanaka, M. Nagayoshi, Y. Takemoto, H. Kusunoki, S. Watanabe

Fertility and Sterility   104   e237 - e238   2015.10

Risk level of intracytoplasmic sperm/spermatid injection for 115 non-mosaic Klinefelter syndrome (KS) patients

T. Miki, A. Tanaka, M. Nagayoshi, I. Tanaka, Y. Takemoto, H. Kusunoki, S. Watanabe

Human Reproduction   30   i101 - i101   2015.7

Development of new procedure to reduce the amount of recipient cytoplasm (mitochondria) at the M-II karyoplast transfer for the treatment of mitochondrial diseases

Tanaka, A. Tanaka, M. Nagayoshi, Y. Takemoto, H. Kusunoki, S. Watanabe

Human Reproduction   30   i143 - i143   2015.7

Is there a future for human round spermatid injection (ROSI)?

A. Tanaka, M. Nagayoshi, Y. Takemoto, I. Tanaka, H. Kusunoki, S. Watanabe

Human Reproduction   30   i143 - i143   2015.7

3. Clinical outcome of spinal cord injured patients with ejaculatory dysfunction.

A. Tanaka, I. Tanaka, M. Nagayoshi, H. Kusunoki and S. Watanabe

Fertility and Sterility   100   S217 - S217   2013.10

8. Higher success rates in thawed embryo transfer during natural cycle after cryopreservation of all fresh embryos.

A. Tanaka, I. Tanaka, M. Nagayoshi, H. Kusunoki and S. Watanabe

Fertility and Sterility   100   S214 - S215   2013.10

7. Rescue of aged oocytes using metaphase-II nuclear transfer with various kinds of fusion techniques.

A. Tanaka, I. Tanaka, M. Nagayoshi, H. Kusunoki and S. Watanabe

Fertility and Sterility   100   S232 - S232   2013.10

6. Risk level of intracytoplasmic sperm/spermatid injection for 115 non-mosaic Klinefelter Syndrome patients.

A. Tanaka, I. Tanaka, M. Nagayoshi, H. Kusunoki and S. Watanabe

Fertility and Sterility   100   S71 - S71   2013.10

5. A comparison of a newly developed round spermatid injection (ROSI) and classical ROSI –reproductive health study on 51　newborn babies

A. Tanaka, I. Tanaka, M. Nagayoshi, H. Kusunoki and S. Watanabe

Fertility and Sterility   100   S29 - S29   2013.10

PGD OR NATURAL CONCEPTION? Recommendations for couples with recurrent miscarriages caused by translocation chromosomal aberrations.

A. Tanaka, I. Tanaka, M. Nagayoshi, H. Kusunoki and S. Watanabe

Fertility and Sterility   100   S203 - S203   2013.10

Clinical comparison of the embryonic development between electrofusion group and no electrofusion group (Transfaction with JSV and Direct injection into the oocyte)

TANAKA Atsushi, TANAKA Izumi, NAGAYOSHI Motoi, KUSUNOKI Hiroshi, WATANABE Seiji

30 ( 2 )   2013.4

Does the Location of the Motor Point Identified with Electrical Stimulation Correspond to that Identified with the Gross Anatomical Method?

NARITA HIROKAZU, YOSHIDA HIDEKI, CHIBA SHOJI, ODA ATSUSHI, ISHIKAWA TAKAAKI, TAKAHASHI NOBUTO, TANI TOSHIKI, WATANABE SEIJI, TONOSAKI YOSHIKAZU

Journal of physical therapy science   23 ( 5 )   737 - 739   2011.10

Syntheses of 2-NBDG analogues for monitoring stereoselective uptake of D-glucose.

Yamamoto T, Tanaka S, Suga S, Watanabe S, Nagatomo K, Sasaki A, Nishiuchi Y, Teshima T, Yamada K

Bioorganic & medicinal chemistry letters   21 ( 13 )   4088 - 96   2011.7

An investigation of the potential effect of vacuoles in human sperm on DNA damage using a chromosome assay and the TUNEL assay.

Watanabe S, Tanaka A, Fujii S, Mizunuma H, Fukui A, Fukuhara R, Nakamura R, Yamada K, Tanaka I, Awata S, Nagayoshi M

Human reproduction (Oxford, England)   26 ( 5 )   978 - 86   2011.5

Syntheses of 2-NBDG analogues for monitoring stereoselective uptake of D-glucose

Yamamoto T, Tanaka S, Suga S, Watanabe S, Nagatomo K, Sasaki A, Nishiuchi Y, Teshima T, Yamada K

Bioorganic & Medical Chemistry Letters   21   4088 - 4096   2011.4

An investigation of the potential effect of vacuoles in human sperm on DNA damage using a chromosome assay and the TUNEL assay

Seiji Watanabe, Atsushi Tanaka, Shunsaku Fujii , Hideki Mizunuma, Atsushi Fukui, Rie Fukuhara, Rika Nakamura, Kenichi Yamada, Izumi Tanaka, Shoichiro Awata, Motoi Nagayoshi

Human Reproduction   26 ( 5 )   978 - 986   2011.2

Does the Location of the Motor Point Identified with Electrical Stimulation Correspond to that Identified with the Gross Anatomical Method?

Narita Hirokazu, Yoshida Hideki, Chiba Shoji, Oda Atsushi, Ishikawa Takaaki, Takahashi Nobuto, Tani Toshiki, Watanabe Seiji, Tonosaki Yoshikazu

Journal of Physical Therapy Science   23 ( 5 )   737 - 739   2011

肉眼解剖による前脛骨筋のモーターポイントの位置の特定

成田 大一, 千葉 正司, 外崎 敬和, 吉田 英樹, 溝畑 日出昌, 渡邉 誠二, 一戸 紀孝

理学療法学Supplement   2009 ( 0 )   A4P2071 - A4P2071   2010

＜Symposium I＞A new imaging method of glucose transport in live cells

Yamada Katsuya, Yamamoto Toshihiro, Watanabe Seiji, Nishiuchi Yuji, Teshima Tadashi, Matsuoka Hideaki, Suga Sechiko

弘前医学   61 ( 0 )   S23 - 25   2010

＜Poster＞Synthesis of 2-NBDLG, the antipode of fluorescent D-glucose tracer 2-NBDG

Yamamoto Toshihiro, Nishiuchi Yuji, Teshima Tadashi, Watanabe Seiji, Suga Sechiko, Matsuoka Hideaki, Yamada Katsuya

弘前医学   61 ( 0 )   S187 - 191   2010

Metaphase II karyoplast transfer from human in-vitro matured oocytes to enucleated mature oocytes.

Tanaka A, Nagayoshi M, Awata S, Himeno N, Tanaka I, Watanabe S, Kusunoki H

Reproductive biomedicine online   19 ( 4 )   514 - 20   2009.10

Metaphase-II karyoplast transfer from human in-vitro matured oocytes to enuclueated mature oocytes

18. A Tanaka, M Nagayoshi, S Awata, N Himeno, I Tanaka, S Watanabe, H Kusunok

Reproductive BioMedicine Online   19 ( 4 )   514 - 520   2009.8

Are Crater Defects in Human Sperm Heads Physiological Changes during Spermiogenesis and Epididymal Maturation?

25   259 - 265   2008.10

非モザイク型クラインフェルター症候群に対する後期精子細胞を用いた顕微授精のリスク

田中温，永吉基，粟田松一郎，姫野憲雄，田中威づみ，竹本洋一，鍬田恵里，渡邉誠二，楠比呂志

産婦人科の実際   57 ( 10 )   1587 - 1595   2008.10

核置換卵子の活性化と染色体分配

渡邉誠二，田中温，田中威づみ，粟田松一郎，永吉基，姫野憲雄，鍬田恵里，竹本洋一

産婦人科の実際   57 ( 10 )   1615 - 1623   2008.10

Are Crater Defects in Human Sperm Heads Physiological Changes during Spermiogenesis and Epididymal Maturation?

TANAKA Atsushi, TANAKA Izumi, NAGAYOSHI Motoi, AWATA Shoichiro, HIMENO Norio, TAKEMOTO Yoichi, KUWATA Eri, AKAHOSHI Takako, WATANABE Seiji, KUSUNOKI Hiroshi

Journal of mammalian ova research   25 ( 4 )   259 - 265   2008.10

No Increased Incidence of Chromosomal Aberrations in Human Spermatozoa with Large Vacuoles by Injection into Mouse Oocytes

WATANABE Seiji, MIZUNUMA Hideki, FUJII Shunsaku, FUKUI Atsushi, KIMURA Hidenori, FUKUHARA Rie, NAKAMURA Rika, YAMADA Takeshi

Journal of mammalian ova research   25 ( 4 )   240 - 245   2008.10

強拡大下で観察される精子頭部空胞様構造と染色体異常の関連性

渡邉誠二，水沼英樹，藤井俊策，福井淳史，木村秀崇，福原理恵，中村理果，山田健市

Journal of Mammalian Ova Research   25   240 - 245   2008.9

核置換卵子の染色体異常

渡邉誠二

日本生殖医療エンジニアリング   2 ( 4 )   4 - 4   2007.2

Embryonic development following the nuclear transfer of in vitro matured metaphase-II oocytes into enucleated freshly ovulated metaphase-II oocytes

A. Tanaka, M. Nagayoshi, S. Awata, N. Himeno, H. Kusunoki and S. Watanabe

Fertility and Sterility   86 ( 3 )   S172 - S172   2006.7

A human blastomere chromosome assay system using electro-fusion with in vitro matured human oocytes

A. Tanaka, M. Nagayoshi, S. Awata, N. Himeno, H. Kusunoki and S. Watanabe

Fertility and Sterility   86 ( 3 )   S481 - S481   2006.7

Physical association of the patient-specific GATA-1 mutants with RUNX1 in acute megakaryo-blastic leukemia accompanying Down syndrome

Gu X, Kanezaki R, Toki T, Watanabe S, Takahashi Y, Terui K, Kitabayashi I, Ito E

Leukemia   20 ( 1 )   1002 - 1008   2006.4

Physiological pineal effect on female reproductive function of laboratory rats: prenatal development of pups, litter size and estrous cycle in middle age

Kachi T. Tanaka D. Watanabe S. Suzuki R. Tonosaki Y. Fujieda H

Chronobiology International   23 ( 1 )   289 - 300   2006.4

Relationship between chromosomal abnormality and head morphology and motility of human spermatozoa

KAMIGUCHI Yujiroh, WATANABE Seiji

23 ( 2 )   2006.4

Physiological pineal effects on female reproductive function of laboratory rats: prenatal development of pups, litter size and estrous cycle in middle age.

Kachi T, Tanaka D, Watanabe S, Suzuki R, Tonosaki Y, Fujieda H

Chronobiology international   23 ( 1-2 )   289 - 300   2006

着床前胚スクリーニングの必要性

竹本洋一，田中温，永吉基，粟田松一郎，姫野憲雄，田中威づみ，鍬田恵理，楠比呂志，渡邉誠二

産婦人科治療   91 ( 6 )   643 - 648   2005.12

Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment

Toki T, Katsuoka F, Kanezaki R, Xu G, Kurotaki H, Sun J, Kamio T, Watanabe S, Tandai S, Terui K, Yagihashi S, Komatsu N, Igarashi K, Yamamoto M, Ito E

Blood   105 ( 8 )   3100 - 3108   2005.4

Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment.

Toki T, Katsuoka F, Kanezaki R, Xu G, Kurotaki H, Sun J, Kamio T, Watanabe S, Tandai S, Terui K, Yagihashi S, Komatsu N, Igarashi K, Yamamoto M, Ito E

Blood   105 ( 8 )   3100 - 8   2005.4

Increased incidence of spontaneous malformations in pups and increased litter size from pinealectomized dams

Takashi K, Tanaka D, Watanabe S, Suzuki R, Tonosaki Y

Anatomical Science International   79 ( 1 )   62 - 71   2004.11

Chromosome analysis of human spermatozoa with morphologically abnormal heads by injection into mouse oocytes

WATANABE SEIJI

Reproductive medicine and biology   3 ( 3 )   147 - 152   2004.9

Chromosome analysis of human spermatozoa with morphologically abnormal heads by injection into mouse oocytes.

Watanabe S

Reproductive medicine and biology   3 ( 3 )   147 - 152   2004.9

Increased incidence of spontaneous malformations in pups and increased litter size from pinealectomized dams

KACHI Takashi, TANAKA Dai, WATANABE Seiji, SUZUKI Reiko, TONOSAKI Yoshikazu

Anatomical science international   79 ( 2 )   62 - 71   2004.6

Increased incidence of spontaneous malformations in pups and increased litter size from pinealectomized dams.

Kachi T, Tanaka D, Watanabe S, Suzuki R, Tonosaki Y

Anatomical science international   79 ( 2 )   62 - 71   2004.6

Chromosome analysis of human spermatozoa with morphologically abnormal heads by injection into mouse oocytes

Watanabe S

Reproductive Medicine and Biology   3 ( 1 )   147 - 152   2004.4

Frequent structural chromosome aberrations in immotile human sperm exposed to culture media.

Watanabe S

Human reproduction (Oxford, England)   19 ( 4 )   940 - 7   2004.4

Frequent structural chromosome aberrations in immotile human sperm exposed to culture media

Watanabe S

Human Reproduction   19 ( 4 )   940 - 947   2004.2

A detailed cytogenetic analysis of large numbers of fresh and frozen-thawed human sperm after ICSI into mouse oocytes.

Watanabe S

Human reproduction (Oxford, England)   18 ( 6 )   1150 - 7   2003.6

A detailed cytogenetic analysis of large numbers of fresh and frozen-thawed human sperm after ICSI into mouse oocytes

Watanabe S

Human Reproduction   18 ( 6 )   1150 - 1157   2003.2