American Association for Cancer Research ; Active membership

The Japan Society of Clinical Immunology

The Japanese Gastroenterological Association

The Japanese Association for Capsule Endoscopy

Japanese Society for Inflammatory Bowel Disease

The Japanese Society for Mucosal Immunology

The Japanese Society of Small Intestinal Disease

The Japanese Society of Geriatric Gastroenterology

Japan Rheumatism Foundation

Japanese Board of Cancer Therapy

Solitary Peutz-Jeghers polyp harboring a focus of high-grade dysplasia in the colon: a case report and literature review.

Takato Maeda, Tadashi Yoshizawa, Takao Oyama, Satoru Nakagawa, Yasuhisa Murai, Ryuma Machida, Nao Ishidoya, Juichi Sakamoto, Hideki Iwamura, Hirotake Sakuraba

Clinical journal of gastroenterology   18 ( 1 )   89 - 94   2025.2

Colorectal Post-polypectomy Bleeding in Outpatient versus Inpatient Treatment: Propensity Score Matching Analysis

Maeda Takato, Sakuraba Hirotake, Oyama Takao, Nakagawa Satoru, Ota Shinji, Murai Yasuhisa, Machida Ryuma, Ishidoya Nao, Kikuchi Hidezumi, Chinda Daisuke, Sakamoto Juichi, Iwamura Hideki

Journal of the Anus, Rectum and Colon   8 ( 3 )   204 - 211   2024.7

Author Correction: ATR inhibition augments the efficacy of lurbinectedin in small-cell lung cancer

Christopher W Schultz, Yang Zhang, Rajaa Elmeskini, Astrid Zimmermann, Haiqing Fu, Yasuhisa Murai, Darawalee Wangsa, Suresh Kumar, Nobuyuki Takahashi, Devon Atkinson, Liton Kumar Saha, Chien-Fei Lee, Brian Elenbaas, Parth Desai, Robin Sebastian, Ajit Kumar Sharma, Melissa Abel, Brett Schroeder, Manan Krishnamurthy, Laurel L Bassel, Rajesh Kumar, Nitin Roper, Mirit Aladjem, Frank T Zenke, Zoe Weaver Ohler, Yves Pommier, Anish Thomas

EMBO Molecular Medicine   16 ( 3 )   664 - 664   2024.2

A Logistic Regression Model for Predicting the Risk of Subsequent Surgery among Patients with Newly Diagnosed Crohn’s Disease Using a Brute Force Method

Kohei Ogasawara, Hiroto Hiraga, Yoshihiro Sasaki, Noriko Hiraga, Naoki Higuchi, Keisuke Hasui, Shinji Ota, Takato Maeda, Yasuhisa Murai, Tetsuya Tatsuta, Hidezumi Kikuchi, Daisuke Chinda, Tatsuya Mikami, Masashi Matsuzaka, Hirotake Sakuraba, Shinsaku Fukuda

Diagnostics   13 ( 23 )   3587 - 3587   2023.12

Schlafen 11 (SLFN11) Kills Cancer Cells Undergoing Unscheduled Re-replication

Junko Murai, Michele Ceribelli, Haiqing Fu, Christophe E. Redon, Ukhyun Jo, Yasuhisa Murai, Mirit I. Aladjem, Craig J. Thomas, Yves Pommier

Molecular Cancer Therapeutics   22 ( 8 )   985 - 995   2023.5

Vitamin A Promotes the Fusion of Autophagolysosomes and Prevents Excessive Inflammasome Activation in Dextran Sulfate Sodium-Induced Colitis

Hiroto Hiraga, Daisuke Chinda, Takato Maeda, Yasuhisa Murai, Kohei Ogasawara, Ryutaro Muramoto, Shinji Ota, Keisuke Hasui, Hirotake Sakuraba, Yoh Ishiguro, Shukuko Yoshida, Krisana Asano, Akio Nakane, Shinsaku Fukuda

International Journal of Molecular Sciences   24 ( 10 )   8684 - 8684   2023.5

Evaluation of Crohn’s Disease Small-Bowel Mucosal Healing Using Capsule Endoscopy and Usefulness of Leucine-Rich α2-Glycoprotein

Hiroto Hiraga, Daisuke Chinda, Keisuke Hasui, Yasuhisa Murai, Takato Maeda, Naoki Higuchi, Kohei Ogasawara, Sae Kudo, Yohei Sawada, Tetsuya Tatsuta, Hidezumi Kikuchi, Mami Ebina, Noriko Hiraga, Tatsuya Mikami, Hirotake Sakuraba, Shinsaku Fukuda

Diagnostics   13 ( 4 )   626 - 626   2023.2

Bacterial exposure risk to the endoscopist's face while performing endoscopy

Kentaro Hoshi, Hidezumi Kikuchi, Koji Narita, Yukari Fukutoku, Taka Asari, Kuniaki Miyazawa, Yasuhisa Murai, Yohei Sawada, Tetsuya Tatsuta, Keisuke Hasui, Hiroto Hiraga, Daisuke Chinda, Tatsuya Mikami, Phawinee Subsomwong, Krisana Asano, Akio Nakane, Shinsaku Fukuda, Hirotake Sakuraba

DEN Open   3 ( 1 )   e209   2023.1

Tacrolimus Up-regulates Expression of TGFβ Receptor Type II via ERK, Providing Protection Against Intestinal Epithelial Injury.

Satake M, Sakuraba H, Hiraga H, Yoshida S, Akemoto Y, Ota S, Murai Y, Hasui K, Kawaguchi S, Kikuchi H, Fukuda S

In vivo (Athens, Greece)   36 ( 4 )   1684 - 1693   2022.7

Polygonum tinctorium leaves suppress sodium dextran sulfate-induced colitis through interleukin-10-related pathway

Taka Asari, Hidezumi Kikuchi, Shogo Kawaguchi, Hirotake Sakuraba, Shukuko Yoshida, Yui Akemoto, Takato Maeda, Ota Shinji, Yasuhisa Murai, Naoki Higuchi, Kentaro Hoshi, Yukari Fukutoku, Hiroto Hiraga, Kenroh Sasaki, Shinsaku Fukuda

Biochemistry and Biophysics Reports   30   101272 - 101272   2022.7

Automated evaluation of colon capsule endoscopic severity of ulcerative colitis using ResNet50

Naoki Higuchi,Hiroto Hiraga,Yoshihiro Sasaki,Noriko Hiraga,Shohei Igarashi,Keisuke Hasui,Kohei Ogasawara,Takato Maeda,Yasuhisa Murai,Tetsuya Tatsuta,Hidezumi Kikuchi,Daisuke Chinda,Tatsuya Mikami,Masashi Matsuzaka,Hirotake Sakuraba,Shinsaku Fukuda

PLOS ONE   17 ( 6 )   e0269728   2022.6

TOP1-DNA trapping by exatecan and combination therapy with ATR inhibitor

Ukhyun Jo, Yasuhisa Murai, Keli K. Agama, Yilun Sun, Liton Kumar Saha, Xi Yang, Yasuhiro Arakawa, Sophia Gayle, Kelli Jones, Vishwas Paralkar, Ranjini K. Sundaram, Jinny Van Doorn, Juan C. Vasquez, Ranjit S. Bindra, Woo Suk Choi, Yves Pommier

Molecular Cancer Therapeutics   21 ( 7 )   1090 - 1102   2022.4

Endoscopic and histopathologic features of Anti-PD-1-related collagenous colitis

Hidezumi Kikuchi, Hirotake Sakuraba, Yui Akemoto, Kazuhiro Hosoi, Yasuhisa Murai, Kentaro Hoshi, Yukari Fukutoku, Taka Asari, Yohei Sawada, Keisuke Hasui, Tetsuya Tatsuta, Hiroto Hiraga, Daisuke Chinda, Tatsuya Mikami, Shinsaku Fukuda

DEN Open   2 ( e92 )   2022.1

Replication-dependent cytotoxicity and Spartan-mediated repair of trapped PARP1–DNA complexes

Liton Kumar Saha, Yasuhisa Murai, Sourav Saha, Ukhyun Jo, Masataka Tsuda, Shunichi Takeda, Yves Pommier

Nucleic Acids Research   49 ( 18 )   10493 - 10506   2021.9

Precision Oncology with Drugs Targeting the Replication Stress, ATR, and Schlafen 11

Ukhyun Jo, Yasuhisa Murai, Naoko Takebe, Anish Thomas, Yves Pommier

Cancers   13 ( 18 )   4601 - 4601   2021.9

Novel and highly potent ATR inhibitor M4344 kills cancer cells with replication stress and enhances the chemotherapeutic activity of widely used DNA damaging agents

Ukhyun Jo, Ilya S Senatorov, Astrid Zimmermann, Liton Kumar Saha, Yasuhisa Murai, Se Hyun Kim, Vinodh N. Rajapakse, Fathi Elloumi, Nobuyuki Takahashi, Christopher W. Schultz, Anish Thomas, Frank T. Zenke, Yves Pommier

Molecular Cancer Therapeutics   20 ( 8 )   1431 - 1441   2021.5

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors

Ukhyun Jo, Yasuhisa Murai, Sirisha Chakka, Lu Chen, Ken Cheng, Junko Murai, Liton Kumar Saha, Lisa M. Miller Jenkins, Yves Pommier

Proceedings of the National Academy of Sciences   118 ( 6 )   e2015654118 - e2015654118   2021.2

Cyclosporine protects from intestinal epithelial injury by modulating butyrate uptake via upregulation of membrane monocarboxylate transporter 1 levels.

Shinji Ota, Hirotake Sakuraba, Hiroto Hiraga, Shukuko Yoshida, Miwa Satake, Yui Akemoto, Nahoko Tanaka, Rina Watanabe, Maeda Takato, Yasuhisa Murai, Kayo Ueno, Takenori Niioka, Makoto Hayakari, Yoh Ishiguro, Shinsaku Fukuda

Biochemistry and biophysics reports   24   100811 - 100811   2020.12

Diagnostic approach for patients with unidentified fever according to the classical criteria of fever of unknown origin in the field of autoimmune disorders.

Rina Watanabe, Hirotake Sakuraba, Hiroto Hiraga, Dai Kishida, Shinji Ota, Keisuke Hasui, Hidezumi Kikuchi, Yui Akemoto, Nahoko Tanaka, Takato Maeda, Yasuhisa Murai, Shukuko Yoshida, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Yoh Ishiguro, Shinsaku Fukuda

Immunological medicine   42 ( 4 )   176 - 184   2019.12

Long-term maintenance of the mucosal healing induced by azacitidine therapy in a patient with intestinal Behçet's-like disease accompanied with myelodysplastic syndrome involving trisomy 8.

Nahoko Tanaka, Hirotake Sakuraba, Hiroto Hiraga, Ko Mayama, Hidezumi Kikuchi, Dai Kishida, Yui Akemoto, Keisuke Hasui, Shinji Ota, Rina Watanabe, Yasuhisa Murai, Takato Maeda, Kosuke Kamata, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Kazufumi Yamagata, Yoh Ishiguro, Masanori Tanaka, Shinsaku Fukuda

Immunological medicine   42 ( 3 )   135 - 141   2019.11

A case of nivolumab-associated colitis, which relapsed after mucosal healing and was then successfully treated with mesalazine.

Hidezumi Kikuchi, Hirotake Sakuraba, Yui Akemoto, Yasuhisa Murai, Yukari Fukutoku, Taka Asari, Tetsuya Tatsuta, Keisuke Hasui, Hiroto Hiraga, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Masanori Tanaka, Shinsaku Fukuda

Immunological medicine   42 ( 1 )   39 - 44   2019.3

Vitamin A Deficiency Impairs Host Resistance to <i>Listeria Monocytogenes</i> Infection Through Excessive Apoptosis of Macrophages

Tanaka Nahoko, Yoshida Shukuko, Asano Krisana, Murai Yasuhisa, Fukuda Shinsaku, Watanabe Rina, Ota Shinji, Akemoto Yui, Hasui Keisuke

Hirosaki Medical Journal   69 ( 1-4 )   163 - 171   2019.3

Vitamin A deficiency impairs host resistance to Listeria Monocytogenes infection through excessive apoptosis of macrophages

Nahoko Tanaka, Hiroto Hiraga, Hirotake Sakuraba, Yasuhisa Murai, Takato Maeda, Rina Watanabe, Shinji Ota, Yui Akemoto, Keisuke Hasui, Shukuko Yoshida, Krisana Asano, Akio Nakane, Shinsaku Fukuda

Hirosaki Medical Journal   69   163 - 171   2019.3