米国癌学会（American Association for Cancer Research）; Active membership

日本臨床免疫学会

日本消化管学会

日本カプセル内視鏡学会

日本炎症性腸疾患学会

日本消化器免疫学会

日本小腸学会

日本高齢消化器病学会

日本リウマチ財団

日本がん治療認定医機構

Solitary Peutz-Jeghers polyp harboring a focus of high-grade dysplasia in the colon: a case report and literature review.

Maeda T, Yoshizawa T, Oyama T, Nakagawa S, Murai Y, Machida R, Ishidoya N, Sakamoto J, Iwamura H, Sakuraba H

Clinical journal of gastroenterology   18 ( 1 )   89 - 94   2025年02月

Colorectal Post-polypectomy Bleeding in Outpatient versus Inpatient Treatment: Propensity Score Matching Analysis.

Maeda T, Sakuraba H, Oyama T, Nakagawa S, Ota S, Murai Y, Machida R, Ishidoya N, Kikuchi H, Chinda D, Sakamoto J, Iwamura H

Journal of the Anus, Rectum and Colon   8 ( 3 )   204 - 211   2024年07月

Author Correction: ATR inhibition augments the efficacy of lurbinectedin in small-cell lung cancer

Christopher W Schultz, Yang Zhang, Rajaa Elmeskini, Astrid Zimmermann, Haiqing Fu, Yasuhisa Murai, Darawalee Wangsa, Suresh Kumar, Nobuyuki Takahashi, Devon Atkinson, Liton Kumar Saha, Chien-Fei Lee, Brian Elenbaas, Parth Desai, Robin Sebastian, Ajit Kumar Sharma, Melissa Abel, Brett Schroeder, Manan Krishnamurthy, Laurel L Bassel, Rajesh Kumar, Nitin Roper, Mirit Aladjem, Frank T Zenke, Zoe Weaver Ohler, Yves Pommier, Anish Thomas

EMBO Molecular Medicine   16 ( 3 )   664 - 664   2024年02月

A Logistic Regression Model for Predicting the Risk of Subsequent Surgery among Patients with Newly Diagnosed Crohn's Disease Using a Brute Force Method.

Ogasawara K, Hiraga H, Sasaki Y, Hiraga N, Higuchi N, Hasui K, Ota S, Maeda T, Murai Y, Tatsuta T, Kikuchi H, Chinda D, Mikami T, Matsuzaka M, Sakuraba H, Fukuda S

Diagnostics (Basel, Switzerland)   13 ( 23 )   3587 - 3587   2023年12月

Schlafen 11 (SLFN11) Kills Cancer Cells Undergoing Unscheduled Re-replication

Junko Murai, Michele Ceribelli, Haiqing Fu, Christophe E. Redon, Ukhyun Jo, Yasuhisa Murai, Mirit I. Aladjem, Craig J. Thomas, Yves Pommier

Molecular Cancer Therapeutics   22 ( 8 )   985 - 995   2023年05月

Vitamin A Promotes the Fusion of Autophagolysosomes and Prevents Excessive Inflammasome Activation in Dextran Sulfate Sodium-Induced Colitis.

Hiraga H, Chinda D, Maeda T, Murai Y, Ogasawara K, Muramoto R, Ota S, Hasui K, Sakuraba H, Ishiguro Y, Yoshida S, Asano K, Nakane A, Fukuda S

International journal of molecular sciences   24 ( 10 )   8684 - 8684   2023年05月

Evaluation of Crohn's Disease Small-Bowel Mucosal Healing Using Capsule Endoscopy and Usefulness of Leucine-Rich α2-Glycoprotein.

Hiraga H, Chinda D, Hasui K, Murai Y, Maeda T, Higuchi N, Ogasawara K, Kudo S, Sawada Y, Tatsuta T, Kikuchi H, Ebina M, Hiraga N, Mikami T, Sakuraba H, Fukuda S

Diagnostics (Basel, Switzerland)   13 ( 4 )   626 - 626   2023年02月

Bacterial exposure risk to the endoscopist's face while performing endoscopy.

Hoshi K, Kikuchi H, Narita K, Fukutoku Y, Asari T, Miyazawa K, Murai Y, Sawada Y, Tatsuta T, Hasui K, Hiraga H, Chinda D, Mikami T, Subsomwong P, Asano K, Nakane A, Fukuda S, Sakuraba H

DEN open   3 ( 1 )   e209   2023年01月

Tacrolimus Up-regulates Expression of TGFβ Receptor Type II via ERK, Providing Protection Against Intestinal Epithelial Injury.

Satake M, Sakuraba H, Hiraga H, Yoshida S, Akemoto Y, Ota S, Murai Y, Hasui K, Kawaguchi S, Kikuchi H, Fukuda S

In vivo (Athens, Greece)   36 ( 4 )   1684 - 1693   2022年07月

Polygonum tinctorium leaves suppress sodium dextran sulfate-induced colitis through interleukin-10-related pathway.

Asari T, Kikuchi H, Kawaguchi S, Sakuraba H, Yoshida S, Akemoto Y, Maeda T, Shinji O, Murai Y, Higuchi N, Hoshi K, Fukutoku Y, Hiraga H, Sasaki K, Fukuda S

Biochemistry and biophysics reports   30   101272 - 101272   2022年07月

Automated evaluation of colon capsule endoscopic severity of ulcerative colitis using ResNet50.

Higuchi N, Hiraga H, Sasaki Y, Hiraga N, Igarashi S, Hasui K, Ogasawara K, Maeda T, Murai Y, Tatsuta T, Kikuchi H, Chinda D, Mikami T, Matsuzaka M, Sakuraba H, Fukuda S

PloS one   17 ( 6 )   e0269728   2022年06月

TOP1-DNA trapping by exatecan and combination therapy with ATR inhibitor.

Jo U, Murai Y, Agama KK, Sun Y, Saha LK, Yang X, Arakawa Y, Gayle S, Jones K, Paralkar V, Sundaram RK, Van Doorn J, Vasquez JC, Bindra RS, Choi WS, Pommier Y

Molecular cancer therapeutics   21 ( 7 )   1090 - 1102   2022年04月

Endoscopic and histopathologic features of Anti-PD-1-related collagenous colitis

Hidezumi Kikuchi, Hirotake Sakuraba, Yui Akemoto, Kazuhiro Hosoi, Yasuhisa Murai, Kentaro Hoshi, Yukari Fukutoku, Taka Asari, Yohei Sawada, Keisuke Hasui, Tetsuya Tatsuta, Hiroto Hiraga, Daisuke Chinda, Tatsuya Mikami, Shinsaku Fukuda

DEN Open   2 ( e92 )   2022年01月

Replication-dependent cytotoxicity and Spartan-mediated repair of trapped PARP1-DNA complexes.

Saha LK, Murai Y, Saha S, Jo U, Tsuda M, Takeda S, Pommier Y

Nucleic acids research   49 ( 18 )   10493 - 10506   2021年09月

Precision Oncology with Drugs Targeting the Replication Stress, ATR, and Schlafen 11.

Jo U, Murai Y, Takebe N, Thomas A, Pommier Y

Cancers   13 ( 18 )   4601 - 4601   2021年09月

Novel and highly potent ATR inhibitor M4344 kills cancer cells with replication stress and enhances the chemotherapeutic activity of widely used DNA damaging agents.

Ukhyun Jo, Ilya S Senatorov, Astrid Zimmermann, Liton Kumar Saha, Yasuhisa Murai, Se Hyun Kim, Vinodh N Rajapakse, Fathi Elloumi, Nobuyuki Takahashi, Christopher W Schultz, Anish Thomas, Frank T Zenke, Yves Pommier

Molecular cancer therapeutics   20 ( 8 )   1431 - 1441   2021年05月

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

Ukhyun Jo, Yasuhisa Murai, Sirisha Chakka, Lu Chen, Ken Cheng, Junko Murai, Liton Kumar Saha, Lisa M Miller Jenkins, Yves Pommier

Proceedings of the National Academy of Sciences of the United States of America   118 ( 6 )   e2015654118 - e2015654118   2021年02月

Cyclosporine protects from intestinal epithelial injury by modulating butyrate uptake via upregulation of membrane monocarboxylate transporter 1 levels.

Ota S, Sakuraba H, Hiraga H, Yoshida S, Satake M, Akemoto Y, Tanaka N, Watanabe R, Takato M, Murai Y, Ueno K, Niioka T, Hayakari M, Ishiguro Y, Fukuda S

Biochemistry and biophysics reports   24   100811 - 100811   2020年12月

Diagnostic approach for patients with unidentified fever according to the classical criteria of fever of unknown origin in the field of autoimmune disorders.

Rina Watanabe, Hirotake Sakuraba, Hiroto Hiraga, Dai Kishida, Shinji Ota, Keisuke Hasui, Hidezumi Kikuchi, Yui Akemoto, Nahoko Tanaka, Takato Maeda, Yasuhisa Murai, Shukuko Yoshida, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Yoh Ishiguro, Shinsaku Fukuda

Immunological medicine   42 ( 4 )   176 - 184   2019年12月

Long-term maintenance of the mucosal healing induced by azacitidine therapy in a patient with intestinal Behçet's-like disease accompanied with myelodysplastic syndrome involving trisomy 8.

Nahoko Tanaka, Hirotake Sakuraba, Hiroto Hiraga, Ko Mayama, Hidezumi Kikuchi, Dai Kishida, Yui Akemoto, Keisuke Hasui, Shinji Ota, Rina Watanabe, Yasuhisa Murai, Takato Maeda, Kosuke Kamata, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Kazufumi Yamagata, Yoh Ishiguro, Masanori Tanaka, Shinsaku Fukuda

Immunological medicine   42 ( 3 )   135 - 141   2019年11月

A case of nivolumab-associated colitis, which relapsed after mucosal healing and was then successfully treated with mesalazine.

Hidezumi Kikuchi, Hirotake Sakuraba, Yui Akemoto, Yasuhisa Murai, Yukari Fukutoku, Taka Asari, Tetsuya Tatsuta, Keisuke Hasui, Hiroto Hiraga, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Masanori Tanaka, Shinsaku Fukuda

Immunological medicine   42 ( 1 )   39 - 44   2019年03月

Vitamin a Deficiency Impairs Host Resistance to Listeria Monocytogenes Infection Through Excessive Apoptosis of macrophages

弘前医学   69 ( 1-4 )   163 - 171   2019年03月

Vitamin A deficiency impairs host resistance to Listeria Monocytogenes infection through excessive apoptosis of macrophages

Nahoko Tanaka, Hiroto Hiraga, Hirotake Sakuraba, Yasuhisa Murai, Takato Maeda, Rina Watanabe, Shinji Ota, Yui Akemoto, Keisuke Hasui, Shukuko Yoshida, Krisana Asano, Akio Nakane, Shinsaku Fukuda

Hirosaki Medical Journal   69   163 - 171   2019年03月

2021年度，特別教育科目（研究室研修），専門教育科目（学部）

2021年度，臨床実習Ⅰ（学内BSL），専門教育科目（学部）

2021年度，臨床実習Ⅱ（クリニカルクラークシップ），専門教育科目（学部）