論文 - 村井 康久
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Precision Oncology with Drugs Targeting the Replication Stress, ATR, and Schlafen 11.
Jo U, Murai Y, Takebe N, Thomas A, Pommier Y
Cancers 13 ( 18 ) 4601 - 4601 2021年09月
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Novel and highly potent ATR inhibitor M4344 kills cancer cells with replication stress and enhances the chemotherapeutic activity of widely used DNA damaging agents.
Ukhyun Jo, Ilya S Senatorov, Astrid Zimmermann, Liton Kumar Saha, Yasuhisa Murai, Se Hyun Kim, Vinodh N Rajapakse, Fathi Elloumi, Nobuyuki Takahashi, Christopher W Schultz, Anish Thomas, Frank T Zenke, Yves Pommier
Molecular cancer therapeutics 20 ( 8 ) 1431 - 1441 2021年05月
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SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.
Ukhyun Jo, Yasuhisa Murai, Sirisha Chakka, Lu Chen, Ken Cheng, Junko Murai, Liton Kumar Saha, Lisa M Miller Jenkins, Yves Pommier
Proceedings of the National Academy of Sciences of the United States of America 118 ( 6 ) e2015654118 - e2015654118 2021年02月
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Cyclosporine protects from intestinal epithelial injury by modulating butyrate uptake via upregulation of membrane monocarboxylate transporter 1 levels.
Ota S, Sakuraba H, Hiraga H, Yoshida S, Satake M, Akemoto Y, Tanaka N, Watanabe R, Takato M, Murai Y, Ueno K, Niioka T, Hayakari M, Ishiguro Y, Fukuda S
Biochemistry and biophysics reports 24 100811 - 100811 2020年12月
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Diagnostic approach for patients with unidentified fever according to the classical criteria of fever of unknown origin in the field of autoimmune disorders.
Rina Watanabe, Hirotake Sakuraba, Hiroto Hiraga, Dai Kishida, Shinji Ota, Keisuke Hasui, Hidezumi Kikuchi, Yui Akemoto, Nahoko Tanaka, Takato Maeda, Yasuhisa Murai, Shukuko Yoshida, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Yoh Ishiguro, Shinsaku Fukuda
Immunological medicine 42 ( 4 ) 176 - 184 2019年12月
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Long-term maintenance of the mucosal healing induced by azacitidine therapy in a patient with intestinal Behçet's-like disease accompanied with myelodysplastic syndrome involving trisomy 8.
Nahoko Tanaka, Hirotake Sakuraba, Hiroto Hiraga, Ko Mayama, Hidezumi Kikuchi, Dai Kishida, Yui Akemoto, Keisuke Hasui, Shinji Ota, Rina Watanabe, Yasuhisa Murai, Takato Maeda, Kosuke Kamata, Tetsuya Tatsuta, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Kazufumi Yamagata, Yoh Ishiguro, Masanori Tanaka, Shinsaku Fukuda
Immunological medicine 42 ( 3 ) 135 - 141 2019年11月
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Long-term maintenance of the mucosal healing induced by azacitidine therapy in a patient with intestinal Behçet's-like disease accompanied with myelodysplastic syndrome involving trisomy 8.
Tanaka N, Sakuraba H, Hiraga H, Mayama K, Kikuchi H, Kishida D, Akemoto Y, Hasui K, Ota S, Watanabe R, Murai Y, Maeda T, Kamata K, Tatsuta T, Sawaya M, Chinda D, Mikami T, Yamagata K, Ishiguro Y, Tanaka M, Fukuda S
Immunological medicine 42 ( 3 ) 135 - 141 2019年09月
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A case of nivolumab-associated colitis, which relapsed after mucosal healing and was then successfully treated with mesalazine.
Hidezumi Kikuchi, Hirotake Sakuraba, Yui Akemoto, Yasuhisa Murai, Yukari Fukutoku, Taka Asari, Tetsuya Tatsuta, Keisuke Hasui, Hiroto Hiraga, Manabu Sawaya, Daisuke Chinda, Tatsuya Mikami, Masanori Tanaka, Shinsaku Fukuda
Immunological medicine 42 ( 1 ) 39 - 44 2019年03月
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Vitamin a Deficiency Impairs Host Resistance to Listeria Monocytogenes Infection Through Excessive Apoptosis of macrophages
弘前医学 69 ( 1-4 ) 163 - 171 2019年03月
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Vitamin A deficiency impairs host resistance to Listeria Monocytogenes infection through excessive apoptosis of macrophages
Nahoko Tanaka, Hiroto Hiraga, Hirotake Sakuraba, Yasuhisa Murai, Takato Maeda, Rina Watanabe, Shinji Ota, Yui Akemoto, Keisuke Hasui, Shukuko Yoshida, Krisana Asano, Akio Nakane, Shinsaku Fukuda
Hirosaki Medical Journal 69 163 - 171 2019年03月
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A case of nivolumab-associated colitis, which relapsed after mucosal healing and was then successfully treated with mesalazine.
Kikuchi H, Sakuraba H, Akemoto Y, Murai Y, Fukutoku Y, Asari T, Tatsuta T, Hasui K, Hiraga H, Sawaya M, Chinda D, Mikami T, Tanaka M, Fukuda S
Immunological medicine 42 ( 1 ) 39 - 44 2019年03月
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‹一般演題抄録›潰瘍性大腸炎の難治化における Schlafen11発現の臨床的意義
村井 康久, 櫻庭 裕丈, 蓮井 桂介, 平賀 寛人, 菊池 英純, 太田 真二, 澤田 洋平, 立田 哲也, 川口 章吾, 明本 由衣, 珍田 大輔, 黒瀬 顕, 三上 達也, 福田 眞作
弘前医学 75 ( 1 ) 79 2024年10月
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‹一般演題抄録›当科の潰瘍性大腸炎の5-アミノサリチル酸製剤の不耐症例の特徴について
福德 友香理, 蓮井 桂介, 平賀 寛人, 小笠原 公平, 珍田 大輔, 村井 康久, 澤田 洋平, 太田 真二, 明本 由衣, 福田 眞作, 速水 史郎, 櫻庭 裕丈, 立田 哲也, 菊池 英純
弘前医学 74 ( 1-4 ) 142 2024年03月
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成人発症IgA血管炎消化管病変評価における小腸カプセル内視鏡の有用性
平賀 寛人, 蓮井 桂介, 小笠原 公平, 村井 康久, 樋口 直樹, 澤田 洋平, 立田 哲也, 平賀 典子, 菊池 英純, 珍田 大輔, 海老名 麻美, 櫻庭 裕丈
日本小腸学会学術集会プログラム・抄録集 6 ( 0 ) 44 - 44 2022年