論文 - 水上 浩哉
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RAGE activation in macrophages and development of experimental diabetic polyneuropathy.
Osonoi S, Mizukami H, Takeuchi Y, Sugawa H, Ogasawara S, Takaku S, Sasaki T, Kudoh K, Ito K, Sango K, Nagai R, Yamamoto Y, Daimon M, Yamamoto H, Yagihashi S.
JCI Insight 7 ( 23 ) e160555. 2022年12月
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Dual epigenetic changes in diabetes mellitus-associated pancreatic ductal adenocarcinoma correlate with downregulation of E-cadherin and worsened prognosis.
1. Hara Y, Mizukami H, Yamazaki K, Yamada T, Igawa A, Takeuchi Y, Sasaki T, Kushibiki H, Murakami K, Kudoh K, Ishido K, Hakamada K.
J Pathol Clin Res. 9 ( 5 ) 354 - 366. 2023年09月
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Diabetes mellitus impacts on expression of DNA mismatch repair protein PMS2 and tumor microenvironment in pancreatic ductal adenocarcinoma.
Pan X, Mizukami H, Hara Y, Yamada T, Yamazaki K, Kudoh K, Takeuchi Y, Sasaki T, Kushibiki H, Igawa A, Hakamada K.
J Diabetes Investig. 14 ( 1 ) 132 - 144 2023年01月
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Pathological substrate of memory impairment in multiple system atrophy.
Miki Y, Tanji K, Shinnai K, Tanaka MT, Altay F, Foti SC, Strand C, Sasaki T, Kon T, Shimoyama S, Furukawa T, Nishijima H, Yamazaki H, Asi YT, Bettencourt C, Jaunmuktane Z, Tada M, Mori F, Mizukami H, Tomiyama M, Lashuel HA, Lashley T, Kakita A, Ling H, Lees AJ, Holton JL, Warner TT, Wakabayashi K.
Neuropathol Appl Neurobiol. 48 ( 7 ) e12844 2022年12月
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The diversity and abundance of gut microbiota are associated with the pain sensation threshold in the Japanese population.
Takeuchi Y, Mizukami H, Kudoh K, Osonoi S, Sasaki T, Kushibiki H, Ogasawara S, Hara Y, Igawa A, Pan X, Yamada T, Yamazaki K, Mikami T, Daimon M, Yagihashi S, Hakamada K, Nakaji S.
Neurobiol Dis. 173 105839. 2022年10月
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Perivascular infiltration reflects subclinical lymph node metastasis in invasive lobular carcinoma.
Igawa A, Mizukami H, Kudoh K, Takeuchi Y, Sasaki T, Pan X, Hakamada K.
Virchows Arch. 481 ( 4 ) 533 - 543 2022年10月
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Protocol to image and analyze the morphology of mouse peripheral nerves using transmission electron microscopy.
Nakai-Shimoda H, Himeno T, Motegi M, Ozeki N, Inoue R, Hayami T, Miura-Yura E, Yamada Y, Morishita Y, Tsunekawa S, Kato Y, Seino Y, Kondo M, Naruse K, Kato K, Mizukami H, Nakamura J, Kamiya H.
STAR Protoc 3 ( 3 ) 101591 2022年08月
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Cumulative autophagy insufficiency in mice leads to progression of β-cell failure.
Suzuki L, Miyatsuka T, Himuro M, Wakabayashi Y, Osonoi S, Miura M, Katahira T, Fujitani Y, Iida H, Mizukami H, Nishida Y, Watada H.
Biochem Biophys Res Commun. 611 38 - 45 2022年06月
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糖尿病性神経障害UPDATE:基礎と臨床の融合
水上浩哉，遲野井祥
糖尿病合併症 36 258 - 261 2022年06月
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Inducible Systemic Gcn1 Deletion in Mice Leads to Transient Body Weight Loss upon Tamoxifen Treatment Associated with Decrease of Fat and Liver Glycogen Storage.
Liu J, Kasai S, Tatara Y, Yamazaki H, Mimura J, Mizuno S, Sugiyama F, Takahashi S, Sato T, Ozaki T, Tanji K, Wakabayashi K, Maeda H, Mizukami H, Shinkai Y, Kumagai Y, Tomita H, Itoh K.
Int J Mol Sci. 23 ( 6 ) 3201 2022年03月
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Kir6.2-deficient mice develop somatosensory dysfunction and axonal loss in the peripheral nerves.
Nakai-Shimoda H, Himeno T, Okawa T, Miura-Yura E, Sasajima S, Kato M, Yamada Y, Morishita Y, Tsunekawa S, Kato Y, Seino Y, Inoue R, Kondo M, Seino S, Naruse K, Kato K, Mizukami H, Nakamura J, Kamiya H.
iScience. 25 ( 1 ) 103609 2021年12月
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A case of dermatofibrosarcoma protuberans with neurofibromatous change.
2021 ( 11 ) rjab472 2021年12月
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Islet microangiopathy and augmented β-cell loss in Japanese non-obese type 2 diabetes patients who died of acute myocardial infarction.
4. Takahashi K, Mizukami H, Osonoi S, Takeuchi Y, Kudoh K, Sasaki T, Daimon M, Yagihashi S.
J Diabetes Investig. 12 ( 12 ) 2149 - 2161 2021年12月
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Diabetes in Humans Activates Pancreatic Stellate Cells via RAGE in Pancreatic Ductal Adenocarcinoma.
Uchida C, Mizukami H, Hara Y, Saito T, Umetsu S, Igawa A, Osonoi S, Kudoh K, Yamamoto Y, Yamamoto H, Yagihashi S, Hakamada K.
Int J Mol Sci. 22 ( 21 ) 11716 2021年10月
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Inhibitory effects of xanthine oxidase inhibitor, topiroxostat, on development of neuropathy in db/db mice
Takahashi K, Mizukami H, Osonoi S, Ogasawara S, Hara Y, Kudoh K, Takeuchi Y, Sasaki T, Daimon M, Yagihashi S
Neurobiol Dis. 155 105392 2021年07月
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MEK/ERK Signaling in β-Cells Bifunctionally Regulates β-Cell Mass and Glucose-Stimulated Insulin Secretion Response to Maintain Glucose Homeostasis.
Diabetes 70 ( 7 ) 1519 - 1535 2021年07月
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Detection of nerve enlargement with ultrasound and correlation with skin biopsy findings in painful sensory neuropathy associated with Sjögren's syndrome.
Yoshida T, Nodera H, Kumon Y, Osanai S, Izumi Y, Mizukami H
Modern rheumatology 31 ( 4 ) 849 - 855 2021年07月
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Inhibitory effects of xanthine oxidase inhibitor, topiroxostat, on development of neuropathy in db/db mice.
Takahashi K, Mizukami H, Osonoi S, Ogasawara S, Hara Y, Kudoh K, Takeuchi Y, Sasaki T, Daimon M, Yagihashi S
Neurobiology of disease 155 105392 2021年07月
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MEK/ERK Signaling in β-Cells Bifunctionally Regulates β-Cell Mass and Glucose-Stimulated Insulin Secretion Response to Maintain Glucose Homeostasis.
Ikushima YM, Awazawa M, Kobayashi N, Osonoi S, Takemiya S, Kobayashi H, Suwanai H, Morimoto Y, Soeda K, Adachi J, Muratani M, Charron J, Mizukami H, Takahashi N, Ueki K
Diabetes 70 ( 7 ) 1519 - 1535 2021年07月
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Islet microangiopathy and augmented β-cell loss in Japanese non-obese type 2 diabetes patients who died of acute myocardial infarction.
Takahashi K, Mizukami H, Osonoi S, Takeuchi Y, Kudoh K, Sasaki T, Daimon M, Yagihashi S
Journal of diabetes investigation 2021年05月